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Plasma electrolytes in elderly patients taking fixed combination diuretic

Bayer, Antony James, Farag, R., Browne, S. and Pathy, M. S. 1986. Plasma electrolytes in elderly patients taking fixed combination diuretic. Postgraduate Medical Journal 62 (725) , pp. 159-162. 10.1136/pgmj.62.725.159

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Plasma potassium and sodium concentrations were measured in a group of elderly patients taking maintenance thiazide diuretic therapy alone, with a potassium supplement or in combination with a potassium sparing diuretic. Fixed dose combinations of a thiazide and potassium sparing diuretic did not significantly reduce the prevalence of hypokalaemia and the combination of amiloride-hydrochlorothiazide was associated with a disproportionate number of cases of hyponatraemia. The desirability of the current widespread use of fixed dose combination diuretics over less expensive single agents is questioned.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: BMJ Publishing Group
ISSN: 0032-5473
Last Modified: 04 Jun 2017 05:11

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