Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Schools (complete)

Group by: Creators | Item Type | Date of Publication | No Grouping
Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1990 | 1989 | 1988 | 1985
Number of items at this level: 569.

2024

Seaton, Gillian, Smith, Hannah, Brancale, Andrea, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2024. Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age. Molecular Cancer 23 (1) , 7. 10.1186/s12943-023-01922-8
file

Tornillo, Giusy, Warrington, Lauren, Kendrick, Howard, Higgins, Adam T. ORCID: https://orcid.org/0000-0002-2906-8151, Hay, Trevor, Beck, Sam and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2024. Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model. Disease Models and Mechanisms 17 (1) , dmm050211. 10.1242/dmm.050211
filefilefile

2023

Almotiri, Alhomidi, Boyd, Ashleigh S. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2023. Zeb1 Regulates the function of lympho-myeloid primed progenitors after transplantation. Biomolecules 13 (9) , 1386. 10.3390/biom13091386
file

Alshahrany, Nawal, Begum, Ayesha, Siebzehnrubl, Dorit, Jimenez-Pascual, Ana and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2023. Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion. Cancer Letters 571 , 216349. 10.1016/j.canlet.2023.216349
file

Arana Echarri, Ainhoa, Struszczak, Lauren, Beresford, Mark, Campbell, John P., Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Thompson, Dylan and Turner, James E. 2023. Immune cell status, cardiorespiratory fitness and body composition among breast cancer survivors and healthy women: a cross sectional study. Frontiers in Physiology 14 , 1107070. 10.3389/fphys.2023.1107070
file

Bates, Emily A., Lovatt, Charlotte, Plein, Alice R., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Engineering adenoviral vectors with improved GBM selectivity. Viruses 15 (5) , 1086. 10.3390/v15051086
file

Brown, J.M.C., Zaben, M. ORCID: https://orcid.org/0000-0002-7446-4532, Ormonde, C., Sharouf, F. ORCID: https://orcid.org/0000-0002-3034-3392, Spencer, R., Bhatt, H., Siebzehnrubl, F.A. ORCID: https://orcid.org/0000-0001-8411-8775 and Gray, W.P. ORCID: https://orcid.org/0000-0001-7595-8887 2023. A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance. Biochemical Pharmacology 208 , 115410. 10.1016/j.bcp.2023.115410
file

Chan, Yee-Hung, Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Ferekidis, Nele, Alshehri, Nouf, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez Gonzalez, Juan B., Plummer, Sue F., Michael, Daryn R., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2023. (+)-catechin attenuates multiple atherosclerosis-associated processes in vitro, modulates disease-associated risk factors in C57BL/6J mice and reduces atherogenesis in LDL receptor deficient mice by inhibiting inflammation and increasing markers of plaque stability. Molecular Nutrition & Food Research 67 (14) , 2200716. 10.1002/mnfr.202200716
file

Edmunds, Grace, Beck, Sam, Umakant Kale, Kedar, Spasic, Irena ORCID: https://orcid.org/0000-0002-8132-3885, O'Neill, Dan, Brodbelt, David and Smalley, Matthew J ORCID: https://orcid.org/0000-0001-9540-1146 2023. Associations between dog breed and clinical features of mammary epithelial neoplasia in bitches: an epidemiological study of submissions to a single diagnostic pathology centre between 2008-2021. Journal of Mammary Gland Biology and Neoplasia 28 (6) 10.1007/s10911-023-09531-3
file

Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Plummer, Ruth, Moreno, Victor, Carter, Louise, Roda, Desamparados, Garralda, Elena, Kristeleit, Rebecca, Sarker, Debashis, Arkenau, Tobias, Roxburgh, Patricia, Walter, Harriet S., Blagden, Sarah, Anthoney, Alan, Klencke, Barbara J., Kowalski, Mark M. and Banerji, Udai 2023. A Phase I/II trial of Oral SRA737 (a Chk1 Inhibitor) given in combination with low-dose gemcitabine in patients with advanced cancer. Clinical Cancer Research 29 (2) , pp. 331-340. 10.1158/1078-0432.CCR-22-2074
file

Kristeleit, Rebecca, Plummer, Ruth, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Carter, Louise, Blagden, Sarah, Sarker, Debashis, Arkenau, Tobias, Evans, Thomas R. Jeffry, Danson, Sarah, Symeonides, Stefan N., Veal, Gareth J., Klencke, Barbara J., Kowalski, Mark M. and Banerji, Udai 2023. A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer. British Journal of Cancer 10.1038/s41416-023-02279-x
file

Michael, D. R., Kerry-Smith, J., Webberley, T. S., Murphy, K.R., Plummer, S. F., Parry, L. ORCID: https://orcid.org/0000-0002-4467-9196 and Marchesi, J. R. ORCID: https://orcid.org/0000-0002-7994-5239 2023. Does flow culture impact upon gut-probiotic interactions: a comparison with static culture. Journal of Functional Foods 104 , 105519. 10.1016/j.jff.2023.105519
file

Moore, Joshua W., Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 and Woolley, Thomas E. ORCID: https://orcid.org/0000-0001-6225-5365 2023. Modelling polarity-driven laminar patterns in bilayer tissues with mixed signalling mechanisms. SIAM Journal on Applied Dynamical Systems 22 (4) , pp. 2945-2990. 10.1137/22M1522565
file

Ordonez, Liliana, Tornillo, Giusy, Kendrick, Howard, Hay, Trevor and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2023. NOTCH and AKT signalling interact to drive mammary tumour heterogeneity. Cancers 15 (17) , 4324. 10.3390/cancers15174324
filefile

Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O'Neill, Niamh S., Gilkes, Amanda, Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 , pp. 276-287. 10.1038/s41375-022-01801-z
file

Sanz-Castillo, Belén, Hurtado, Begoña, Vara-Ciruelos, Diana, El Bakkali, Aicha, Hermida, Dario, Salvador-Barbero, Beatriz, Martínez-Alonso, Diego, González-Martínez, José, Santiveri, Clara, Campos-Olivas, Ramón, Ximénez-Embún, Pilar, Muñoz, Javier, Álvarez-Fernández, Mónica and Malumbres, Marcos 2023. The MASTL/PP2A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner. The EMBO Journal 42 (2) , e110833. 10.15252/embj.2022110833

Shorning, Boris, Trent, Neil, Griffiths, David F., Worzfeld, Thomas, Offermanns, Stefan, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Williamson, Magali 2023. Plexin-B1 mutation drives metastasis in prostate cancer mouse models. Cancer Research Communications 3 (3) , pp. 444-458. 10.1158/2767-9764.CRC-22-0480
file

Singh, Niharika, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Martinez Garay, Isabel ORCID: https://orcid.org/0000-0001-6849-7496 2023. Transcriptional control of embryonic and adult neural progenitor activity. Frontiers in Neuroscience 17 , 1217596. 10.3389/fnins.2023.1217596
file

Varney, Danielle, O'Neill, Dan, O'Neill, Maeve, Church, David, Stell, Anneliese, Beck, Sam, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Brodbelt, David 2023. Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016. Veterinary Record 193 (5) , e3054. 10.1002/vetr.3054
file

2022

Almotiri, Alhomidi, Abdelfattah, Ali and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2022. Flow cytometry analysis of hematopoietic stem/progenitor cells and mature blood cell subsets in atherosclerosis. Ramji, Dipak, ed. Atherosclerosis, Vol. 2419. Methods in Molecular Biology, Springer, pp. 583-595. (10.1007/978-1-0716-1924-7_36)

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Buettner, Florian, Mian, Syed A., Rhys, Hefin, Perez-Lloret, Jimena, Garcia-Albornoz, Manuel, Rastogi, Namrata, Ariza-McNaughton, Linda and Bonnet, Dominique 2022. Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population. Nature Communications 13 , 2048. 10.1038/s41467-022-29675-w
file

Banerjee, Susana, Michalarea, Vasiliki, Ang, Joo Ern, Ingles Garces, Alvaro, Biondo, Andrea, Funingana, Ionut-Gabriel, Little, Martin, Ruddle, Ruth, Raynaud, Florence, Riisnaes, Ruth, Gurel, Bora, Chua, Sue, Tunariu, Nina, Porter, Joanna C., Prout, Toby, Parmar, Mona, Zachariou, Anna, Turner, Alison, Jenkins, Ben, McIntosh, Stuart, Ainscow, Edward, Minchom, Anna, Lopez, Juanita, de Bono, Johann, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Hall, Emma, Cook, Natalie, Basu, Bristi and Banerji, Udai 2022. A phase I trial of CT900, a novel α-folate receptor-mediated thymidylate synthase inhibitor, with expansion cohorts in patients with high grade serous ovarian cancer. Clinical Cancer Research 22 , 1268. 10.1158/1078-0432.CCR-22-1268

Bates, Emily A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Vánová, Jana, Nestic, Davor, Meniel, Valerie S., Koushyar, Sarah, Cunliffe, Tabitha G., Mundy, Rosie M., Moses, Elise, Uusi-Kerttula, Hanni K., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Majhen, Dragomira, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2022. Development of a low seroprevalence, αvβ6 integrin selective virotherapy based on human adenovirus type 10. Molecular Therapy - Oncolytics 25 , pp. 43-56. 10.1016/j.omto.2022.03.007
file

D'Ambrogio, Joshua, Hill, Liam and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2022. Cell competition: Clonal competition protects against early tumorigenesis. Current Biology 32 (1) , PR52-R54. 10.1016/j.cub.2021.11.029
file

Dimitriou, Pantelitsa, Li, Jin ORCID: https://orcid.org/0000-0002-4672-6806, Tornillo, Giusy, Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 and Barrow, David ORCID: https://orcid.org/0000-0003-2096-7262 2022. Droplet incubator: a new droplet-based model to investigate living cell-synthetic cell interactions. Presented at: MicroTAS 2022, Hangzhou, China, 23-27 October 2022.

Engel, Rebekah M., Jardé, Thierry, Oliva, Karen, Kerr, Genevieve, Chan, Wing Hei, Hlavca, Sara, Nickless, David, Archer, Stuart K., Yap, Raymond, Ranchod, Pravin, Bell, Stephen, Niap, Ann, Koulis, Christine, Chong, Ashley, Wilkins, Simon, Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963, Hollins, Andrew J. ORCID: https://orcid.org/0000-0002-0324-9376, McMurrick, Paul J. and Abud, Helen E. 2022. Modeling colorectal cancer: A bio-resource of 50 patient-derived organoid lines. Journal of Gastroenterology and Hepatology 37 (5) , pp. 898-907. 10.1111/jgh.15818
file

Hidalgo, Manuel, Garcia-Carbonero, Rocio, Lim, Kian-Huat, Messersmith, Wells A., Garrido-Laguna, Ignacio, Borazanci, Erkut, Lowy, Andrew M., Medina Rodriguez, Laura, Laheru, Daniel, Salvador-Barbero, Beatriz, Malumbres, Marcos, Shields, David J., Grossman, Joseph E., Huang, Xin, Tammaro, Meggan, Martini, Jean-François, Yu, Yanke, Kern, Kenneth and Macarulla, Teresa 2022. A preclinical and phase Ib study of palbociclib plus nab-paclitaxel in patients with metastatic adenocarcinoma of the pancreas. Cancer Research Communications 2 (11) , 1326–1333. 10.1158/2767-9764.CRC-22-0072
file

Howell, Sacha J., Casbard, Angela ORCID: https://orcid.org/0000-0001-6241-3052, Carucci, Margherita, Ingarfield, Kate, Butler, Rachel, Morgan, Sian, Meissner, Magdalena, Bale, Catherine, Bezecny, Pavel, Moon, Sarah, Twelves, Chris, Venkitaraman, Ramachandran, Waters, Simon, De Bruin, Elza C., Schiavon, Gaia, Foxley, Andrew and Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496 2022. Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial. The Lancet Oncology 23 (7) , pp. 851-864. 10.1016/s1470-2045(22)00284-4
file

Koushyar, Sarah, Meniel, Valerie S., Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2022. Exploring the Wnt pathway as a therapeutic target for prostate cancer. Biomolecules 12 (2) , 309. 10.3390/biom12020309
file

May, Stephanie, Greenow, Kirsty, Higgins, Adam ORCID: https://orcid.org/0000-0002-2906-8151, Derrick, Anna, Taylor, Elaine, Pan, Pan, Konstantinou, Maria, Nixon, Colin, Woolley, Thomas ORCID: https://orcid.org/0000-0001-6225-5365, Sansom, Owen, Wang, Li-Shu and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2022. Modification of diet to reduce the stemness and tumourigenicity of murine and human intestinal cells. Molecular Nutrition & Food Research 66 (19) , 2200234. 10.1002/mnfr.202200234
file

Menendez-Gonzalez, Juan Bautista, Strange, Kathryn E., Bassetto, Marcella, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ferla, Salvatore 2022. Ligand-based discovery of a novel GATA2 inhibitor targeting acute myeloid leukemia cells. Frontiers In Drug Discovery 2 , 1013229. 10.3389/fddsv.2022.1013229
file

Menendez-Gonzalez, Juan Bautista and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2022. Exploring the associations between clonal hematopoiesis of indeterminate potential, myeloid malignancy, and atherosclerosis. Ramji, Dipak, ed. Atherosclerosis, Vol. 2419. Methods in Molecular Biology, Springer, pp. 73-88. (10.1007/978-1-0716-1924-7_5)

Moore, Joshua W., Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 and Woolley, Thomas E. ORCID: https://orcid.org/0000-0001-6225-5365 2022. Polarity driven laminar pattern formation by lateral-inhibition in 2D and 3D bilayer geometries. IMA Journal of Applied Mathematics 87 (4) , pp. 568-606.
file

Morgan, Huw J., Rees, Elise, Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Powell, Kate A., Gore, Jasmine, Gibbs, Alex, Lovatt, Charlotte, Davies, Gemma E., Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Shorning, Boris Y., Tornillo, Giusy, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Patel, Girish K. 2022. CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation 132 (21) , e150750. 10.1172/JCI150750
file

Owen, Jasmine S., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2022. Cancer-associated fibroblast heterogeneity, activation and function: implications for prostate cancer. Biomolecules 13 (1) , 67. 10.3390/biom13010067
file

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2022. Stemming the flow toward disease: A research profile of Lee Parry. eFood 3 (6) , e46. 10.1002/efd2.46
file

Petrik, David ORCID: https://orcid.org/0000-0003-3026-0770, Jorgensen, Sara, Eftychidis, Vasileios and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2022. Singular adult neural stem cells do not exist. Cells 11 (4) , 722. 10.3390/cells11040722
file

Routledge, Daniel, Rogers, Sally, Ono, Yosuke, Brunt, Lucy, Meniel, Valerie, Tornillo, Giusy, Ashktorab, Hassan, Phesse, Toby J ORCID: https://orcid.org/0000-0001-9568-4916 and Scholpp, Steffen 2022. The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer. eLife 11 , e77376. 10.7554/elife.77376
filefile

Saad, Fred, Thiery-Vuillemin, Antoine, Wiechno, Pawel, Alekseev, Boris, Sala, Nuria, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Kocak, Ivo, Chiuri, Vincenzo Emanuele, Jassem, Jacek, Fléchon, Aude, Redfern, Charles, Kang, Jinyu, Burgents, Joseph, Gresty, Christopher, Degboe, Arnold and Clarke, Noel W 2022. Patient-reported outcomes with olaparib plus abiraterone versus placebo plus abiraterone for metastatic castration-resistant prostate cancer: a randomised, double-blind, phase 2 trial. The Lancet Oncology 23 (10) , pp. 1297-1307. 10.1016/S1470-2045(22)00498-3
file

Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2022. Isolating and culturing of precursor cells from the adult human brain. Deleyrolle, Loic P., ed. Neural Progenitor Cells: Methods and Protocols, Vol. 2389. Methods in Molecular Biology, New York, NY: Springer, pp. 95-102. (10.1007/978-1-0716-1783-0_9)

Williams, Non G. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2022. Balancing the scales: Do healthy lifestyle choices offset the colorectal cancer risk of unhealthy choices? eFood 3 (6) , e45. 10.1002/efd2.45
file

Woolley, Thomas ORCID: https://orcid.org/0000-0001-6225-5365, Hill, William and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2022. Accounting for dimensional differences in stochastic domain invasion with applications to precancerous cell removal. Journal of Theoretical Biology 541 , 111024. 10.1016/j.jtbi.2022.111024
file

2021

Abdelfattah, Ali Mahmoud, Hughes-Davies, Antonia, Clayfield, Liam Daniel, Menendez-Gonzalez, Juan Bautista, Almotiri, Alhomidi, Alotaibi, Badi, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Rodrigues, Neil P ORCID: https://orcid.org/0000-0002-1925-7733 2021. Gata2 haploinsufficiency promotes proliferation and functional decline of HSCs with myeloid bias during aging. Blood Advances 5 (20) , pp. 4285-4290. 10.1182/bloodadvances.2021004726
file

Almotiri, Alhomidi, Alzahrani, Hamed Ahmad A., Menendez-Gonzalez, Juan Bautista, Abdelfattah, Ali, Alotaibi, Badi, Saleh, Lubaid, Greene, Adelle, Georgiou, Mia R. F., Gibbs, Alex, Alsayari, Amani Salem, Taha, Sarab, Thomas, Leigh-Anne, Shah, Dhruv, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Boyd, Ashleigh S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2021. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. Journal of Clinical Investigation 131 (1) , e129115. 10.1172/JCI129115
file

Arana Echarri, Ainhoa, Beresford, Mark, Campbell, John P., Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Butler, Rachel, Gollob, Kenneth J., Brum, Patricia C., Thompson, Dylan and Turner, James E. 2021. A phenomic perspective on factors influencing breast cancer treatment: integrating aging and lifestyle in blood and tissue biomarker profiling. Frontiers in Immunology 11 , 616188. 10.3389/fimmu.2020.616188
file

Castro, Jessica, Tornillo, Giusy, Ceada, Gerardo, Ramos-Neble, Beatriz, Bravo, Marlon, Ribo', Marc, Vilanova, Maria, Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 and Benito, Antoni 2021. A nuclear-directed ribonuclease variant targets cancer stem cells and inhibits migration and invasion of breast cancer cells. Cancers 13 (17) , 4350. 10.3390/cancers13174350
file

Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Uusi-Kerttula, Hanni K., Seaton, Gillian, Piggott, Luke, Badder, Luned M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20. Viruses 13 (5) , 864. 10.3390/v13050864
file

Dimitriou, Pantelitsa, Li, Jin ORCID: https://orcid.org/0000-0002-4672-6806, Tornillo, Giusy, McCloy, Thomas and Barrow, David ORCID: https://orcid.org/0000-0003-2096-7262 2021. Droplet microfluidics for tumor drug-related studies and programmable artificial cells. Global Challenges 5 (7) , 2000123. 10.1002/gch2.202000123
file

Edmunds, Grace L., Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Beck, Sam, Errington, Rachel J. ORCID: https://orcid.org/0000-0002-8016-4376, Gould, Sara, Winter, Helen, Brodbelt, David and O'Neill, Dan 2021. Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine Medicine and Genetics 8 , 2. 10.1186/s40575-021-00100-7
file

Gupta, Bhavana, Errington, Adam C. ORCID: https://orcid.org/0000-0002-2171-389X, Jimenez-Pascual, Ana, Eftychidis, Vasileios, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas, Petrik, David ORCID: https://orcid.org/0000-0003-3026-0770 and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2021. The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus. Cell Reports 36 (8) , 109588. 10.1016/j.celrep.2021.109588
file

Hill, William, Zaragkoulias, Andreas, Salvador-Barbero, Beatriz, Parfitt, Geraint ORCID: https://orcid.org/0000-0002-8704-7906, Alatsatianos, Markella, Padilha, Ana, Porazinski, Sean, Woolley, Thomas E. ORCID: https://orcid.org/0000-0001-6225-5365, Morton, Jennifer P., Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2021. EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neigbors in the adult pancreas. Current Biology 31 (12) , pp. 2550-2560. 10.1016/j.cub.2021.03.094
file

Jukes, Zoe, Freier, Anne, Glymenaki, Maria, Brown, Richard, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Want, Elizabeth, Vorkas, Panagiotis A. and Li, Jia V. 2021. Lipid profiling of mouse intestinal organoids for studying APC mutations. Bioscience Reports 41 (3) , BSR20202915. 10.1042/BSR20202915
file

Kermanizadeh, Ali, Jacobsen, Nicklas Raus, Murphy, Fiona, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Zhang, Haiyuan and Møller, Peter 2021. A review of the current state of nanomedicines for targeting and treatment of cancers - achievements and future challenges. Advanced Therapeutics 4 (2) , 2000186. 10.1002/adtp.202000186
file

Lawson, Hannah, Sepulveda, Catarina, van de Latemaat, Louie N., Durko, Jozef, Barile, Melania, Tavosanis, Andrea, Georges, Elise, Shmakova, Alena, Timms, Penny, Carter, Roderick N., Allen, Lewis, Campos, Joana, Vukovic, Milica, Guitart, Amelie V., Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, O'Shea, Marie, Vernimmen, Douglas, Morton, Nicholas M., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Gottgens, Berthold, Schofield, Christopher J., Lengeling, Andreas, O'Carroll, Donal and Kranc, Kamil R. 2021. JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells. Blood Advances 5 (3) , pp. 889-899. 10.1182/bloodadvances.2020002702
file

Lawson, Hannah, van de Lagemaat, Louie N., Barile, Melania, Tavosanis, Andrea, Durko, Jozef, Villacreces, Arnaud, Bellani, Aarushi, Mapperley, Christopher, Georges, Elise, Martins-Costa, Catarina, Sepulveda, Catarina, Allen, Lewis, Campos, Joana, Campbell, Kirsteen J., O'Carroll, Donal, Gottgens, Berthold, Cory, Suzanne, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Guitart, Amelie V. and Kranc, Kamil R. 2021. CITED2 coordinates key haematopoietic regulatory pathways to maintain the HSC pool in both steady-state haematopoiesis and transplantation. Stem Cell Reports 16 (11) , pp. 2784-2797. 10.1016/j.stemcr.2021.10.001
file

Mian, Syed A., Dos Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2021. Advances in human immune system mouse models for studying human hematopoiesis and cancer immunotherapy. Frontiers in Immunology 11 , 619236. 10.3389/fimmu.2020.619236
file

Moore, Joshua W., Lau, Zechariah, Kaouri, Katerina ORCID: https://orcid.org/0000-0002-9850-253X, Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 and Woolley, Thomas E. ORCID: https://orcid.org/0000-0001-6225-5365 2021. A general computational framework for COVID-19 modelling with applications to testing varied interventions in education environments. COVID 1 (4) , pp. 674-703. 10.3390/covid1040055
file

Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Al-Ahmadi, Wijdan, O'Morain, Victoria, Chan, Yee-Hung, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez-Gonzalez, Juan B., Almotiri, Alhomidi, Plummer, Sue F., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Michael, D. R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. Food and Function 12 (8) , pp. 3657-3671. 10.1039/D0FO02867C
file

O'Morain, Victoria L., Chan, Yee-Hung, Williams, Jessica O., Alotibi, Reem, Alahmadi, Alaa, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Plummer, Sue F., Hughes, Timothy R., Michael, Daryn R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. The Lab4P consortium of probiotics attenuates atherosclerosis in LDL receptor deficient mice fed a high fat diet and causes plaque stabilization by inhibiting inflammation and several pro-atherogenic processes. Molecular Nutrition & Food Research 65 (17) , 2100214. 10.1002/mnfr.202100214
file

Ordonez, Liliana D., Melchor, Lorenzo, Greenow, Kirsty R., Kendrick, Howard, Tornillo, Giusy, Bradford, James, Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854 and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2021. Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model. Disease Models and Mechanisms 14 (5) , dmm048736. 10.1242/dmm.048736
file

Pope, Iestyn ORCID: https://orcid.org/0000-0002-4104-0389, Masia, Francesco ORCID: https://orcid.org/0000-0003-4958-410X, Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Jimenez-Pascual, Ana, Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 and Langbein, Wolfgang ORCID: https://orcid.org/0000-0001-9786-1023 2021. Identifying subpopulations in multicellular systems by quantitative chemical imaging using label-free hyperspectral CARS microscopy. Analyst 146 (7) , pp. 2277-2291. 10.1039/D0AN02381G
file

Rastogi, Namrata, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Uger, Robert A., Wong, Mark, Coles, Steve J., Hodges, Marie, Gilkes, Amanda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2021. Use of an anti-CD200 blocking antibody improves immune responses to AML in vitro and in vivo. British Journal of Haematology 193 (1) , pp. 155-159. 10.1111/bjh.17125
file

Seligmann, Jenny F., Fisher, David J., Brown, Louise C., Adams, Richard A. ORCID: https://orcid.org/0000-0003-3915-7243, Graham, Janet, Quirke, Philip, Richman, Susan D., Butler, Rachel, Domingo, Enric, Blake, Andrew, Yates, Emma, Braun, Michael, Collinson, Fiona, Jones, Rob ORCID: https://orcid.org/0000-0003-3576-9496, Brown, Ewan, de Winton, Emma, Humphrey, Timothy C., Parmar, Mahesh, Kaplan, Richard, Wilson, Richard H., Seymour, Matthew and Maughan, Timothy S. 2021. Inhibition of WEE1 is effective in TP53- and RAS-mutant metastatic colorectal cancer: a randomized trial (FOCUS4-C) comparing adavosertib (AZD1775) with active monitoring. Journal of Clinical Oncology 39 (33) , pp. 3705-3715. 10.1200/JCO.21.01435
file

Soukupova, Jitka, Bordoni, Cinzia, Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Yang, William W., Seaton, Gillian, Gruca, Aleksandra, French, Rhiannon, Lee, Kok Yung, Varnava, Athina, Piggott, Luke, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2021. The discovery of a novel anti-metastatic Bcl3 inhibitor. Molecular Cancer Therapeutics 10 (5) , pp. 775-786. 10.1158/1535-7163.MCT-20-0283
file

Stott, Katie J., Phillips, Bethan, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and May, Stephanie 2021. Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer. Bioscience Reports 41 (7) , BSR20204113. 10.1042/BSR20204113
file

Tran, Bang Manh, Flanagan, Dustin James, Phesse, Toby James ORCID: https://orcid.org/0000-0001-9568-4916, Vincan, Elizabeth and Phesse, Toby 2021. Frizzled7 activates β-catenin-dependent and β-catenin-independent Wnt signalling pathways during developmental morphogenesis: implications for therapeutic targeting in colorectal cancer. Handbook of Experimental Pharmacology,

2020

Adams-Smith, Rebecca, Colmont, C., Mukhtar, A., Morgan, H. and Patel, G. K. 2020. A novel oncostatin M/interleukin-31 receptor mutation in familial primary localized cutaneous amyloidosis. Clinical and Experimental Dermatology 45 (2) , pp. 254-256. 10.1111/ced.14059
file

Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Gilkes, Amanda F., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2020. Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. Leukemia 34 (2) , pp. 427-440. 10.1038/s41375-019-0596-4
file

Badder, Luned M., Hollins, Andrew J. ORCID: https://orcid.org/0000-0002-0324-9376, Herpers, Bram, Yan, Kuan, Ewan, Kenneth B. ORCID: https://orcid.org/0000-0001-6622-9009, Thomas, Mairian, Shone, Jennifer R., Badder, Delyth A., Naven, Marc ORCID: https://orcid.org/0000-0002-6339-3257, Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X, Esdar, Christina, Buchstaller, Hans-Peter, Treherne, J. Mark, Boj, Sylvia, Ramezanpour, Bahar, Wienke, Dirk, Price, Leo S., Shaw, Paul H. ORCID: https://orcid.org/0000-0002-7467-0619 and Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 2020. 3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors. PLoS ONE 15 (8) , e0235319. 10.1371/journal.pone.0235319
file

Badr, Christian E., Silver, Daniel J., Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Deleyrolle, Loic P. 2020. Metabolic heterogeneity and adaptability in brain tumors. Cellular and Molecular Life Sciences 77 , pp. 5101-5119. 10.1007/s00018-020-03569-w
file

Caye, Aurélie, Rouault-Pierre, Kevin, Strullu, Marion, Lainey, Elodie, Abarrategi, Ander, Fenneteau, Odile, Arfeuille, Chloé, Osman, Jennifer, Cassinat, Bruno, Pereira, Sabrina, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Currie, Erin, Ariza-McNaughton, Linda, Barlogis, Vincent, Dalle, Jean-Hugues, Baruchel, André, Chomienne, Christine, Cavé, Hélène and Bonnet, Dominique 2020. Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment. Leukemia 34 , pp. 1658-1668. 10.1038/s41375-019-0662-y
file

Hong, David S., Concin, Nicole, Vergote, Ignace, de Bono, Johann S., Slomovitz, Brian M, Drew, Yvette, Arkenau, Hendrik-Tobias, Machiels, Jean-Pascal, Spicer, James, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Forster, Martin, Cornez, Nathalie, Gennigens, Christine, Johnson, Melissa L, Thistlethwaite, Fiona C, Rangwala, Reshma A, Ghatta, Srinivas, Windfeld, Kristian, Harris, Jeffrey R, Lassen, Ulrik Niels and Coleman, Robert L. 2020. Tisotumab vedotin in previously treated recurrent or metastatic cervical cancer. Clinical Cancer Research 26 (6) , pp. 1220-1228. 10.1158/1078-0432.CCR-19-2962
file

Jardé, Thierry, Chan, Wing Hei, Rossello, Fernando J., Kaur Kahlon, Tanvir, Theocharous, Mandy, Kurian Arackal, Teni, Flores, Tracey, Giraud, Mégane, Richards, Elizabeth, Chan, Eva, Kerr, Genevieve, Engel, Rebekah M., Prasko, Mirsada, Donoghue, Jacqueline F., Abe, Shin-ichi, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Nefzger, Christian M., McMurrick, Paul J., Powell, David R., Daly, Roger J., Polo, Jose M. and Abud, Helen E. 2020. Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium. Cell Stem Cell 27 (4) , 646-662.E7. 10.1016/j.stem.2020.06.021
file

Jimenez-Pascual, Ana, Mitchell, Kelly, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Lathia, Justin D. 2020. FGF2: a novel druggable target for glioblastoma? Expert Opinion on Therapeutic Targets 24 (4) , pp. 311-318. 10.1080/14728222.2020.1736558
file

Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Casbard, Angela ORCID: https://orcid.org/0000-0001-6241-3052, Carucci, Margherita, Cox, Catrin, Butler, Rachel, Alchami, Fouad, Madden, Tracie-Ann ORCID: https://orcid.org/0000-0001-7880-7873, Bale, Catherine, Bezecny, Pavel, Joffe, Johnathan, Moon, Sarah, Twelves, Chris, Venkitaraman, Ramachandran, Waters, Simon, Foxley, Andrew and Howell, Sacha J. 2020. Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial. Lancet Oncology 21 (3) , pp. 345-347. 10.1016/S1470-2045(19)30817-4
file

Kiraga, Lukasz, Cerutti, Gabriele, Braniewska, Agata, Strzemecki, Damian, Sas, Zuzanna, Boffi, Alberto, Savino, Carmelinda, Montemiglio, Linda Celeste, Turnham, Daniel ORCID: https://orcid.org/0000-0002-2540-7363, Seaton, Gillian, Bonamore, Alessandra, Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673, Dabkowski, Adam M., Paisey, Stephen J., Taciak, Bartlomiej, Kucharzewska, Paulina, Rygiel, Tomasz P. and Król, Magdalena 2020. Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice. International Journal of Molecular Sciences 21 (14) , 4991. 10.3390/ijms21144991
file

Koushyar, Sarah, Powell, Arfon G. ORCID: https://orcid.org/0000-0002-3740-8275, Vincan, Elizabeth and Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 2020. Targeting Wnt signaling for the treatment of gastric cancer. International Journal of Molecular Sciences 21 (11) , 3927. 10.3390/ijms21113927
file

May, Stephanie, McDermott, Grace, Marchesi, Julian ORCID: https://orcid.org/0000-0002-7994-5239 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2020. Impact of black raspberries on the normal and malignant Apc deficient murine gut microbiome. Journal of Berry Research 10 (1) , pp. 61-76. 10.3233/JBR-180372
file

May, Stephanie, Parry, Connor and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2020. Berry chemoprevention: do berries decrease the window of opportunity for tumourigenesis. Food Frontiers 1 (3) 10.1002/fft2.32
file

Morgan, H. J., Benketah, A., Olivero, C. ORCID: https://orcid.org/0000-0002-8961-6703, Rees, E., Ziaj, S., Mukhtar, A., Lanfredini, S. ORCID: https://orcid.org/0000-0002-3160-5120 and Patel, G. K. 2020. Human basal cell carcinoma: the induction of anagen hair follicle differentiation. Clinical and Experimental Dermatology 45 (3) , pp. 309-317. 10.1111/ced.14108
file

Peltola, Katriina J., Bono, Petri, Jones, Robert Hugh ORCID: https://orcid.org/0000-0003-3576-9496, Vjaters, Egils, Nykänen, Pirjo, Vuorela, Annamari, Oksala, Riikka, Pohjanjousi, Pasi, Mustonen, Mika V.J., Fizazi, Karim and Massard, Christopher 2020. ODM-204, a novel dual Inhibitor of CYP17A1 and androgen receptor: early results from phase I dose escalation in men with castration-resistant prostate cancer. European Urology Focus 6 (1) , pp. 63-70. 10.1016/j.euf.2018.08.022
file

Pires, Ana, Greenshields Watson, Alexander, Jones, Emma, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Kendrick, Howard, Hindley, James P., French, Rhiannon, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Watkins, William John ORCID: https://orcid.org/0000-0003-3262-6588, Andrews, Robert, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8 (12) , 1520 - 1531. 10.1158/2326-6066.CIR-20-0070
file

Queiroz, Cleberson J.S., Song, Fei, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Al-Khafaji, Nadeem, Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X, Vimalachandran, Dale, Miyajima, Fabio, Pritchard, D. Mark and Jenkins, John R. 2020. NAP1L1: a novel human colorectal cancer biomarker derived from animal models of Apc inactivation. Frontiers in Oncology 10 , 1565. 10.3389/fonc.2020.01565
filefile

Regan, Joseph L and Smalley, Matthew J ORCID: https://orcid.org/0000-0001-9540-1146 2020. Integrating single-cell RNA-sequencing and functional assays to decipher mammary cell states and lineage hierarchies. NPJ Breast Cancer 6 , 32. 10.1038/s41523-020-00175-8
file

Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader, Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2020. Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3. Cancer Research 80 (5) , pp. 937-949. 10.1158/0008-5472.CAN-19-1920
file

Salvador, Beatriz, Álvarez-Fernández, Mónica, Zapatero-Solana, Elisabet, El Bakkali, Aicha, Menéndez, María del Camino, López-Casas, Pedro P., Di Domenico, Tomas, Xie, Tao, VanArsdale, Todd, Shields, David J., Hidalgo, Manuel and Malumbres, Marcos 2020. CDK4/6 inhibitors impair recovery from cytotoxic chemotherapy in pancreatic adenocarcinoma. Cancer Cell 37 (3) , pp. 340-353. 10.1016/j.ccell.2020.01.007

Scholz, Nico, Kurian, Kathreena M., Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Licchesi, Julien D. F. 2020. Targeting the ubiquitin system in glioblastoma. Frontiers in Oncology 10 , 574011. 10.3389/fonc.2020.574011
file

Shorning, Boris Y., Dass, Manisha S., Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2020. The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT signaling. International Journal of Molecular Sciences 21 (12) , 4507. 10.3390/ijms21124507
file

Tran, Bang Manh, Flanagan, Dustin James, Ebert, Gregor, Warner, Nadia, Tran, Hoanh, Fifis, Theodora, Kastrappis, Georgios, Christophi, Christopher, Pellegrini, Marc, Torresi, Joseph, Phesse, Toby James ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2020. The hepatitis B virus pre-core protein p22 activates Wnt sgnaling. Cancers 12 (6) , 1435. 10.3390/cancers12061435
file

Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Bullock, Nicholas, Dass, Manisha S., Staffurth, John N. ORCID: https://orcid.org/0000-0002-7834-3172 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2020. The PTEN conundrum: how to target PTEN-deficient prostate cancer. Cells 9 (11) , 2342. 10.3390/cells9112342
file

Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Yang, William W., Davies, Julia, Varnava, Athina, Ridley, Anne J., Conlan, R. Steven and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2020. Bcl-3 promotes multi-modal tumour cell migration via NF-kB1 mediated regulation of Cdc42. Carcinogenesis 41 (10) , pp. 1432-1443. 10.1093/carcin/bgaa005
file

Valle-Encinas, Eider and Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 2020. Wnt ligand and receptor patterning in the liver. Current Opinion in Cell Biology 62 , pp. 17-25. 10.1016/j.ceb.2019.07.014
file

2019

de Bono, Johann S., Concin, Nicole, Hong, David S., Thistlethwaite, Fiona C., Machiels, Jean-Pascal, Arkenau, Hendrik-Tobias, Plummer, Ruth, Jones, Robert Hugh ORCID: https://orcid.org/0000-0003-3576-9496, Nielsen, Dorte, Windfeld, Kristian, Ghatta, Srinivas, Slomovitz, Brian M., Spicer, James F., Yachnin, Jeffrey, Ang, Joo Ern, Mau-Sørensen, Paul Morten, Forster, Martin David, Collins, Dearbhaile, Dean, Emma, Rangwala, Reshma A. and Lassen, Ulrik 2019. Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial. Lancet Oncology 20 (3) , pp. 383-393. 10.1016/S1470-2045(18)30859-3
file

Eissman, Moritz F, Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Brunnberg, Jamina, Poh, Ashleigh R, Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas H, Hibbs, Margaret L, Boussioutas, Alex, Grimbaldeston, Michele A, Buchert, Michael, O'Donoghue, Robert J J, Masson, Frederick and Ernst, Matthias 2019. IL-33 mediated mast cell activation promotes gastric cancer through macrophage mobilization. Nature Communications 10 , 2735. 10.1038/s41467-019-10676-1
filefile

Flanagan, Dustin, Barker, Nick, Ernst, Matthias, Vincan, Elizabeth and Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 2019. The function of Lgr5+ cells in the gastric antrum does not require Fzd7 or Myc in vivo. Biomedicines 7 (3) , 50. 10.3390/biomedicines7030050
file

Flanagan, Dustin J., Barker, Nick, Di Costanzo, Natasha S., Mason, Elizabeth A., Gurney, Austin, Meniel, Valerie S., Koushyar, Sarah, Austin, Chloe R., Ernst, Matthias, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Boussioutas, Alex, Clevers, Hans, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2019. Frizzled-7 is required for Wnt signaling in gastric tumours with and without Apc mutations. Cancer Research 79 (5) , pp. 970-981. 10.1158/0008-5472.CAN-18-2095
filefilefilefilefilefilefilefilefile

Flanagan, Dustin J, Vincan, Elizabeth and Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 2019. Wnt signaling in cancer: not a binary ON:OFF switch. Cancer Research 10.1158/0008-5472.CAN-19-1362
file

French, Rhiannon and Tornillo, Giusy 2019. Heterogeneity of mammary stem cells. Advances in Experimental Medicine and Biology 1169 , pp. 119-140. 10.1007/978-3-030-24108-7_7

Healey, Gareth D., Pan-Castillo, Belen, Garcia-Parra, Jezabel, Davies, Julia, Roberts, Shaun, Jones, Eilir, Dhar, Kalyan, Nandanan, Sarika, Tofazzal, Nasima, Piggott, Luke, Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673, Seaton, Gillian, Frostell, Asa, Fagge, Tim, McKee, Colin, Margarit, Lavinia, Conlan, R. Steven and Gonzalez, Deyarina 2019. Antibody drug conjugates against the receptor for advanced glycation end products (RAGE), a novel therapeutic target in endometrial cancer. Journal for ImmunoTherapy of Cancer 7 (1) , 280. 10.1186/s40425-019-0765-z
file

Hill, William and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2019. Normal epithelial cells trigger EphA2-dependent RasV12 cell repulsion at the single cell level. Small GTPases 10 (4) , pp. 305-310. 10.1080/21541248.2017.1324940
file

Jimenez-Pascual, Ana, Lathia, Justin D. and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2019. ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells. Molecular & Cellular Oncology 7 (1) , 1684787. 10.1080/23723556.2019.1684787
file

Jimenez-Pascual, Ana, Hale, James S., Kordowski, Anja, Pugh, Jamie, Silver, Daniel J., Bayik, Defne, Roversi, Gustavo, Alban, Tyler J., Rao, Shilpa, Chen, Rui, McIntyre, Thomas M., Colombo, Giorgio, Taraboletti, Giulia, Holmberg, Karl O., Forsberg-Nilsson, Karin, Lathia, Justin D. and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2019. ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells. Cancer Discovery 9 (11) , pp. 1574-1589. 10.1158/2159-8290.CD-18-1308
filefilefilefilefilefilefile

Jimenez-Pascual, Ana and Siebzehnrubl, Florian A ORCID: https://orcid.org/0000-0001-8411-8775 2019. Fibroblast growth factor receptor functions in glioblastoma. Cells 8 (7) , 715. 10.3390/cells8070715
file

Kannen, Vinicius, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Martin, Francis L. 2019. Phages enter the fight against colorectal cancer. Trends in Cancer 5 (10) , pp. 577-579. 10.1016/j.trecan.2019.08.002
file

Legge, Danny N., Shephard, Alex P., Collard, Tracey J., Greenhough, Alexander, Chambers, Adam C., Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Paraskeva, Christos and Williams, Ann C. 2019. BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells. Disease Models and Mechanisms 12 (3) , 037697. 10.1242/dmm.037697
file

Menendez Gonzalez, Juan Bautista, Sinnadurai, Samantha, Gibbs, Alex, Thomas, Leigh-anne, Konstantinou, Maria, Garcia Valverde, Alfonso, Boyer, Magali, Wang, Zhengke, Boyd, Ashleigh S., Blair, Allison, Morgan, Rhys G. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2019. Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. Scientific Reports 9 , 12212. 10.1038/s41598-019-48589-0
file

Menendez Gonzalez, Juan Bautista, Vukovic, Milica, Abdelfattah, Ali, Saleh, Lubaid, Almotiri, Alhomidi, Thomas, Leigh-anne, Agirre-Lizaso, Alona, Azevedo, Aleksandra, Menezes, Ana Catarina, Tornillo, Giusy, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Kong, Kay, Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, Anjos-Afonso, Fernando, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Boyd, Ashleigh S., Kranc, Kamil R. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2019. Gata2 as a crucial regulator of stem cells in adult hematopoiesis and acute myeloid leukemia. Stem Cell Reports 13 (2) , pp. 291-306. 10.1016/j.stemcr.2019.07.005
file

Menendez-Gonzalez, Juan Bautista, Saleh, Lubaid, Feng, Gui Jie and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2019. Isolation of murine hematopoietic stem cells. Boyd, Ashleigh S., ed. Immunological Tolerance: Methods and Protocols, Vol. 1899. Methods in Molecular Biology, New York: Humana Press, pp. 15-23. (10.1007/978-1-4939-8938-6_2)

Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19 , 677. 10.1186/s12885-019-5867-y
filefilefilefilefilefilefilefilefile

Ordonez, Liliana D, Hay, Trevor, McEwen, Robert, Polanska, Urszula M, Hughes, Adina, Delpuech, Oona, Cadogan, Elaine, Powell, Steve, Dry, Jonathan, Tornillo, Giusy, Silcock, Lucy, Leo, Elisabetta, O'Connor, Mark J, Clarke, Alan R ORCID: https://orcid.org/0000-0002-4281-426X and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2019. Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours. Oncotarget 10 (27) , pp. 2586-2606. 10.18632/oncotarget.26830
file

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Phesse, Toby J ORCID: https://orcid.org/0000-0001-9568-4916 2019. FXR regulates intestinal stem cells response to bile acids in a high fat diet. Biotarget 3 (12) 10.21037/biotarget.2019.07.01
file

Young, Madeleine A., May, Stephanie, Damo, Angelos, Yoon, Young So, Hur, Man-Wook, Swat, Wojiech and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2019. Epigenetic regulation of Dlg1, via Kaiso, alters mitotic spindle polarity and promotes intestinal tumourigenesis. Molecular Cancer Research 17 (3) , pp. 686-696. 10.1158/1541-7786.MCR-18-0280
file

Young, Rodrigo M., Ewan, Kenneth B. ORCID: https://orcid.org/0000-0001-6622-9009, Ferrer, Veronica P., Allende, Miguel L., Godovac-Zimmermann, Jasminka, Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 and Wilson, Stephen W. 2019. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. eLife 8 , e51447. 10.7554/eLife.51447
file

2018

Basu, B., Krebs, M. G., Sundar, R., Wilson, R. H., Spicer, J., Jones, R. ORCID: https://orcid.org/0000-0003-3576-9496, Brada, M., Talbot, D. C., Steele, N., Ingles Garces, A. H., Brugger, W., Harrington, E. A., Evans, J., Hall, E., Tovey, H., de Oliveira, F. M., Carreira, S., Swales, K., Ruddle, R., Raynaud, F. I., Purchase, B., Dawes, J. C., Parmar, M., Turner, A. J., Tunariu, N., Banerjee, S., de Bono, J. S. and Banerji, U. 2018. Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer. Annals of Oncology 29 (9) , pp. 1918-1925. 10.1093/annonc/mdy245
file

Borgogna, Cinzia, Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Calati, Federica, De Andrea, Marco, Zavattaro, Elisa, Savoia, Paola, Trisolini, Elena, Boldorini, Renzo, Patel, Girish K. and Gariglio, Marisa 2018. β-HPV infection correlates with early stages of carcinogenesis in skin tumors and patient-derived xenografts from a kidney transplant recipient cohort. Frontiers in Microbiology 9 , 117. 10.3389/fmicb.2018.00117
file

Boyd, Ashleigh S. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2018. Stem cells cycle toward immune surveillance. Immunity 48 (2) , pp. 187-190. 10.1016/j.immuni.2018.02.006
file

Burke, Zoe D., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Yeh, Sheng-Wen, Meniel, Valerie S., Sansom, Owen J., Clarke, Alan R. and Tosh, David 2018. Spatiotemporal regulation of liver development by the Wnt/β- catenin pathway. Scientific Reports 8 , 2735. 10.1038/s41598-018-20888-y
file

Clarke, Noel, Wiechno, Pawel, Alekseev, Boris, Sala, Nuria, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Kocak, Ivo, Chiuri, Vincenzo Emanuele, Jassem, Jacek, Fléchon, Aude, Redfern, Charles, Goessl, Carsten, Burgents, Joseph, Kozarski, Robert, Hodgson, Darren, Learoyd, Maria and Saad, Fred 2018. Olaparib combined with abiraterone in patients with metastatic castration-resistant prostate cancer: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Oncology 19 (7) , pp. 975-986. 10.1016/S1470-2045(18)30365-6
file

Flanagan, Dustin, Austin, Chloe, Vincan, Elizabeth and Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 2018. Wnt Signalling in gastrointestinal epithelial stem cells. Genes 9 (4) , 178. 10.3390/genes9040178
file

Greenow, Kristy R., Zverev, Matthew, May, Stephanie, Kendrick, Howard, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2018. Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis. Oncotarget 9 (92) , pp. 36430-36443. 10.18632/oncotarget.26335
file

Hill, William 2018. Heterotypic cell-cell interactions between KrasG12D cells and normal neighbours in early pancreatic cancer. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Hoang-Minh, Lan B., Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775, Yang, Changlin, Suzuki-Hatano, Silveli, Dajac, Kyle, Loche, Tyler, Andrews, Nicholas, Massari, Michael Schmoll, Patel, Jaimin, Amin, Krisha, Vuong, Alvin, Jimenez Pascual, Ana, Kubilis, Paul, Garrett, Timothy J., Moneypenny, Craig, Pacak, Christina A., Huang, Jianping, Sayour, Elias J., Mitchell, Duane A., Sarkisian, Matthew R., Reynolds, Brent . and Deleyrolle, Loic P. 2018. Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. EMBO Journal 37 (23) , e98772. 10.15252/embj.201798772
filefile

Lopez-Millan, Belen, Diaz de la Guardia, Rafael, Roca-Ho, Heleia, Anguita, Eduardo, Islam, Abul B. M. M. K., Romero-Moya, Damia, Prieto, Cristina, Gutierrez-Agüera, Francisco, Bejarano-Garcia, Jose Antonio, Perez-Simon, Jose Antonio, Costales, Paula, Rovira, Montse, Marín, Pedro, Menendez, Silvia, Iglesias, Mar, Fuster, Jose Luis, Urbano-Ispizua, Alvaro, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Bueno, Clara and Menendez, Pablo 2018. IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML. OncoImmunology 7 (9) , e1477460. 10.1080/2162402X.2018.1477460
file

May, Stephanie, Owen, Heather, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Greenow, Kristy R., Jones, Gareth-Rhys, Blackwood, Adam, Cook, Peter C., Towers, Christopher, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Williams, Geraint T., Sturzl, Michael, Britzen-Laurent, Nathalie, Sansom, Owen J., MacDonald, Andrew S., Bird, Adrian P., Clarke, Alan R. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2018. Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation. Journal of Pathology 245 (3) , pp. 270-282. 10.1002/path.5074
filefilefile

Morgan, Huw 2018. Elucidating the role of TGFβ signalling in drug resistant Hh driven cancers. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Borgogna, Cinzia, Gariglio, Marisa and Patel, Girish K. 2018. HPV-induced field cancerisation: Transformation of adult tissue stem cell into cancer stem cell. Frontiers in Microbiology 9 , 546. 10.3389/fmicb.2018.00546
file

Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Morgan, Huw and Patel, Girish K. 2018. Identification of human cutaneous squamous cell carcinoma cancer stem cells. Turksen, Kursad, ed. Skin Stem Cells, Vol. 1879. Methods in Molecular Biology, Humana Press, pp. 415-433. (10.1007/7651_2018_134)

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Li, Jason, Meniel, Valerie S., Fennell, Christina M., Waring, Paul, Montgomery, Karen G., Rebello, Richard J., Macpherson, Arthi A., Koushyar, Sarah, Furic, Luc, Cullinane, Carleen, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Simpson, Kaylene J., Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Shepherd, Peter R., Humbert, Patrick O., Sansom, Owen J. and Phillips, Wayne A. 2018. Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth. Cancer Discovery 8 (6) , pp. 764-779. 10.1158/2159-8290.CD-17-0867
file

Piggott, Luke, Silva, Ana ORCID: https://orcid.org/0000-0002-1184-4909, Robinson, Timothy, Santiago-Gomez, Angelica, Simoes, Bruno M., Becker, Michael, Fichtner, Iduna, Andera, Ladislav, Young, Philippa, Morris, Christine, Barret-Lee, Peter, Alchami, Fouad, Piva, Marco, Vivanco, Maria d. M., Clarke, Robert B., Gee, Julia ORCID: https://orcid.org/0000-0001-6483-2015 and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2018. Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through post-translational downregulation of c-FLIP. Clinical Cancer Research 24 (10) , pp. 2452-2463. 10.1158/1078-0432.CCR-17-1381
filefilefilefilefilefilefile

Pope, I. ORCID: https://orcid.org/0000-0002-4104-0389, Masia, F. ORCID: https://orcid.org/0000-0003-4958-410X, Bradley, J., Ewan, K. ORCID: https://orcid.org/0000-0001-6622-9009, Karuna, A., Payne, L., Guschina, I., Harwood, J. ORCID: https://orcid.org/0000-0003-2377-2612, Swann, K. ORCID: https://orcid.org/0000-0002-4355-1449, Dale, T. ORCID: https://orcid.org/0000-0002-4880-9963, Watson, P. ORCID: https://orcid.org/0000-0003-0250-7852, Langbein, W. ORCID: https://orcid.org/0000-0001-9786-1023 and Borri, P. ORCID: https://orcid.org/0000-0002-7873-3314 2018. Coherent Raman Scattering microscopy: technology developments and biological applications. Presented at: 20th International Conference on Transparent Optical Networks (ICTON), Bucharest, Romania, 1-5 Jul 2018. 20th International Conference on Transparent Optical Networks (ICTON). IEEE, 10.1109/ICTON.2018.8473706
file

Prim Padilha, Ana 2018. Molecular and functional characterization of the role of Foxp3+ regulatory T (Treg) cells in the development of intestinal cancer. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Puig Barbe, Aleix 2018. A network of bHLH factors controls self-renewal and bipotential differentiation in the Drosophila intestine. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775, Raber, Kerstin A., Urbach, Yvonne K., Schulze-Krebs, Anja, Canneva, Fabio, Moceri, Sandra, Habermeyer, Johanna, Achoui, Dalila, Gupta, Bhavana, Steindler, Dennis A., Stephan, Michael, Nguyen, Huu Phuc, Bonin, Michael, Riess, Olaf, Bauer, Andreas, Aigner, Ludwig, Couillard-Despres, Sebastien, Paucar, Martin Arce, Svenningsson, Per, Osmand, Alexander, Andreew, Alexander, Zabel, Claus, Weiss, Andreas, Kuhn, Rainer, Moussaoui, Saliha, Blockx, Ines, Van der Linden, Annemie, Cheong, Rachel Y., Roybon, Laurent, Petersén, Åsa and von Hörsten, Stephan 2018. Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition. Proceedings of the National Academy of Sciences 115 (37) , E8765-E8774. 10.1073/pnas.1807962115
file

Tornillo, Giusy, Knowlson, Catherine, Kendrick, Howard, Cooke, Joe, Mirza, Hasan, Aurrekoetxea-Rodriguez, Iskander, d.M. Vivanco, Maria, Buckley, Niamh E., Grigoriadis, Anita and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2018. Dual mechanisms of LYN kinase dysregulation drive aggressive behaviour in breast cancer cells. Cell Reports 25 (13) , pp. 3674-3692. 10.1016/j.celrep.2018.11.103
file

Vincan, Elizabeth, Schwab, Renate H.M., Flanagan, Dustin J., Moselen, Jean M., Tran, Bang M., Barker, Nick and Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 2018. The central role of Wnt signaling and organoid technology in personalizing anticancer therapy. Progress in Molecular Biology and Translational Science 153 , pp. 299-319. 10.1016/bs.pmbts.2017.11.009
filefilefilefilefilefile

2017

Badder, Luned 2017. Developing stem-cell containing organoids as a pre-clinical model for colorectal cancer therapeutics. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Berenjeno, Inma M., Piñeiro, Roberto, Castillo, Sandra D., Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M., Meniel, Valerie, Birkbak, Nicolai J., Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E. R., Montgomery, Karen G., Moniz, Larissa S., Scudamore, Cheryl L., Phillips, Wayne A., Semple, Robert K., Clarke, Alan, Swanton, Charles and Vanhaesebroeck, Bart 2017. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications 8 (1) , 1773. 10.1038/s41467-017-02002-4
file

Carotenuto, Pietro, Fassan, Matteo, Pandolfo, Rosantony, Lampis, Andrea, Vicentini, Caterina, Cascione, Luciano, Paulus-Hock, Viola, Boulter, Luke, Guest, Rachel, Quagliata, Luca, Hahne, Jens Claus, Ridgway, Rachel, Jamieson, Tam, Athineos, Dimitris, Veronese, Angelo, Visone, Rosa, Murgia, Claudio, Ferrari, Giulia, Guzzardo, Vincenza, Evans, Thomas Ronald Jeffry, MacLeod, Martin, Feng, Gui Ji, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Negrini, Massimo, Forbes, Stuart J, Terracciano, Luigi, Scarpa, Aldo, Patel, Tushar, Valeri, Nicola, Workman, Paul, Sansom, Owen and Braconi, Chiara 2017. Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers. Gut 66 (7) , pp. 1268-1277. 10.1136/gutjnl-2016-312278
file

Chen, Hung-Chang, Joalland, Noémie, Bridgeman, John S, Alchami, Fouad S, Jarry, Ulrich, Khan, Mohd Wajid A, Piggott, Luke, Shanneik, Yasmin, Li, Jianqiang, Herold, Marco J, Herrmann, Thomas, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Scotet, Emmanuel, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7) , pp. 620-629. 10.1038/icb.2017.21
file

Chiang, Kelly, Zielinska, Agnieszka E., Shaaban, Abeer M., Sanchez-Bailon, Maria Pilar, Jarrold, James, Clarke, Thomas L, Zhang, Jingxian, Francis, Adele, Jones, Louise J., Smith, Sally, Barbash, Olena, Guccione, Ernesto, Farnie, Gillian, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Davies, Clare C. 2017. PRMT5 is a critical regulator of breast cancer stem cell function via Histone Methylation and FOXP1 expression. Cell Reports 21 (12) , pp. 3498-3513. 10.1016/j.celrep.2017.11.096
file

Colbeck, Emily J., Jones, Emma, Hindley, James P., Smart, Kathryn, Schulz, Ralph, Browne, Molly, Cutting, Scott, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ware, Carl F., Ager, Ann and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2017. Treg depletion licenses T cell-driven HEV neogenesis and promotes tumor destruction. Cancer Immunology Research 5 (11) , pp. 1005-1015. 10.1158/2326-6066.CIR-17-0131
file

Dietrich, Laura, Rathmer, Bernd, Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Bange, Tanja, Stefan, Heinrichs, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Dennis, Schade and Grossmann, Tom N. 2017. Cell permeable stapled peptide inhibitor of Wnt signaling that targets β-catenin protein‒protein interactions. Cell Chemical Biology 24 (8) , pp. 958-968. 10.1016/j.chembiol.2017.06.013
file

Flanagan, Dustin J, Vincan, Elizabeth and Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 2017. Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers. British Journal of Pharmacology 174 (24) , pp. 4666-4683. 10.1111/bph.13890
Item availability restricted.
file

Flanagan, Dustin J., Barker, Nick, Nowell, Cameron, Clevers, Hans, Ernst, Matthias, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2017. Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo. Disease Models and Mechanisms 10 (8) , pp. 971-980. 10.1242/dmm.029876
file

Garcia Martin, Isabel, Janssen, A.B., Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Grimstead, Julia W., Penketh, Richard J. A., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and John, Rosalind M. ORCID: https://orcid.org/0000-0002-3827-7617 2017. Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis. Placenta 59 , pp. 61-68. 10.1016/j.placenta.2017.09.007
file

Guitart, Amelie V, Panagopoulou, Theano I, Villacreces, Arnaud, Vukovic, Milica, Sepulveda, Catarina, Allen, Lewis, Carter, Roderick N, Lagemaat, Louie N van de, Morgan, Marcos, Giles, Peter, Sas, Zuzanna, Gonzalez, Marta Vila, Lawson, Hannah, Paris, Jasmin, Edwards-Hicks, Joy, Schaak, Katrin, Subramani, Chithra, Gezer, Deniz, Armesilla-Diaz, Alejandro, Wills, Jimi Carlo, Easterbrook, Aaron, Coman, David, Wai, Chi, So, Eric, O'Carroll, Donal, Vernimmen, Douglas, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Pollard, Patrick J, Morton, Nicholas M, Finch, Andrew and Kranc, Kamil R 2017. Fumarate hydratase is a critical regulator of hematopoietic stem cell functions. Journal of Experimental Medicine 214 (3) , -. 10.1084/jem.20161087
file

Helft, Julie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, van der Veen, Annemarthe G., Chakravarty, Probir, Bonnet, Dominique and Reis e Sousa, Caetano 2017. Dendritic cell lineage potential in human early hematopoietic progenitors. Cell Reports 20 (3) , pp. 529-537. 10.1016/j.celrep.2017.06.075
file

Hwang, Ho Sik, Parfitt, Geraint J. ORCID: https://orcid.org/0000-0002-8704-7906, Brown, Donald J. and Jester, James V. 2017. Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD). Experimental Eye Research 163 , pp. 37-45. 10.1016/j.exer.2017.02.008
file

Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G. ORCID: https://orcid.org/0000-0003-1902-9930, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. 2017. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis. Journal of Pathology 243 (4) , pp. 442-456. 10.1002/path.4977
filefilefilefilefile

Kay, Sophie K., Harrington, Heather A., Shepherd, Sarah, Brennan, Keith, Dale, Trevor ORCID: https://orcid.org/0000-0002-4880-9963, Osborne, James M., Gavaghan, David J. and Byrne, Helen M. 2017. The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt. PLoS Computational Biology 13 (2) , e1005400. 10.1371/journal.pcbi.1005400
file

Konstantinou, Maria 2017. Characterising In-111-anti-γH2AX-TAT in targeting the DNA damage signal associated with Wnt activated colorectal cancer. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Lampreia, Fabio Pereira, Carmelo, Joana Gonçalves and Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X 2017. Notch signaling in the regulation of hematopoietic stem cell. Current Stem Cell Reports 10.1007/s40778-017-0090-8
file

Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Borgogna, Cinzia, Calati, Federica, Powell, Kathryn, Davies, Kelli-Jo, De Andrea, Marco, Harries, Sarah, Tang, Hiu, Pfister, Herbert, Gariglio, Marisa and Patel, Girish K 2017. HPV8 field cancerization in a transgenic mouse model is due to Lrig1+Keratinocyte stem cell expansion. Journal of Investigative Dermatology 137 (10) , pp. 2208-2216. 10.1016/j.jid.2017.04.039
file

Liu, David S., Duong, Cuong P., Haupt, Sue, Montgomery, Karen G., House, Colin M., Azar, Walid J., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Fisher, Oliver M., Read, Matthew, Guerra, Glen R., Haupt, Ygal, Cullinane, Carleen, Wiman, Klas G., Abrahmsen, Lars, Phillips, Wayne A. and Clemons, Nicholas J. 2017. Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation. Nature Communications 8 , 14844. 10.1038/ncomms14844
file

Martin, Ana Carolina B.M., Fuzer, Angelina M., Becceneri, Amanda B., da Silva, James Almada, Tomasin, Rebeka, Denoyer, Delphine, Kim, Soo-Hyun, McIntyre, Katherine A., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Yeo, Belinda, Nagpal, Aadya, Ling, Xiawei, Selistre-de-Araújo, Heloisa S., Vieira, Paulo Cézar, Cominetti, Marcia R. and Pouliot, Normand 2017. [10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo. Oncotarget 8 (42) , pp. 72260-72271. 10.18632/oncotarget.20139
file

May, Stephanie, Evans, Samantha and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2017. Organoids, organs-on-chips and other systems, and microbiota. Emerging Topics in Life Sciences 1 (4) , pp. 385-400. 10.1042/ETLS20170047
file

Menendez Gonzalez, Juan Bautista 2017. Exploring the role of GATA2 in normal and malignant haematopoiesis. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Mohamed, Noha-Ehssan 2017. Characterizing the roles of APC2 protein in ovarian homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
file

Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Sansom, Owen J. 2017. Lgr5 joins the club of gastric stem cell markers in the corpus. Nature Cell Biology 19 (7) , pp. 752-754. 10.1038/ncb3567
file

Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Marsh Durban, Victoria and Sansom, Owen J. 2017. Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models. Carcinogenesis 38 (10) , pp. 953-965. 10.1093/carcin/bgx080
file

Planells-Palop, Vicente, Hazazi, Ali, Feichtinger, Julia, Jezkova, Jana, Thallinger, Gerhard, Alsiwiehri, Naif O., Almutairi, Mikhlid, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Wakeman, Jane A. and McFarlane, Ramsay J. 2017. Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Molecular Cancer 16 , 84. 10.1186/s12943-017-0653-4
file

Portero Migueles, Rosa, Shaw, Louise, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, May, Gillian, Henseleit, Korinna, Anderson, Kathryn G. V., Goker, Hakan, Jones, C. Michael, de Bruijn, Marella F. T. R., Brickman, Joshua M. and Enver, Tariq 2017. Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny. Developmental Biology 424 (2) , pp. 236-245. 10.1016/j.ydbio.2016.12.021
file

Roy, Ananya, Attarha, Sanaz, Weishaupt, Holger, Edqvist, Per-Henrik, Swartling, Fredrik J., Bergqvist, Michael, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Smits, Anja, Pontén, Fredrik and Tchougounova, Elena 2017. Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression. Oncotarget 8 , pp. 24815-24827. 10.18632/oncotarget.15820
file

Schwab, Renate H.M., Amin, Nancy, Flanagan, Dustin J., Johanson, Timothy M., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2017. Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells. Developmental Dynamics 247 (3) , pp. 521-530. 10.1002/dvdy.24527
file

Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Blount, Daniel, Brewster, Alison, Gwynne, Sarah, Harrop, Richard, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. MVA-5T4 immunotherapy and low-dose cyclophosphamide for advanced colorectal cancer (TaCTiCC): An open-label, randomized phase I/II trial. Journal of Clinical Oncology 35 (7) , p. 154. 10.1200/JCO.2017.35.7_suppl.154
file

Scurr, Martin J ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom, Bloom, Anja, Roberts, David J, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard A ORCID: https://orcid.org/0000-0003-3915-7243, Brewster, Alison E, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. Low-dose cyclophosphamide induces anti-tumor T-cell responses which associate with survival in metastatic colorectal cancer. Clinical Cancer Research , clincanres.0895.2017. 10.1158/1078-0432.CCR-17-0895
file

Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom ORCID: https://orcid.org/0000-0002-2600-2034, Bloom, Anja, Roberts, David, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Brewster, Alison, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Wright, Melissa ORCID: https://orcid.org/0000-0002-1011-4795, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. Effect of modified vaccinia Ankara–5T4 and low-dose cyclophosphamide on antitumor immunity in metastatic colorectal cancer: A randomized clinical trial. JAMA Oncology 3 (10) , e172579. 10.1001/jamaoncol.2017.2579
file

Soady, Kelly J., Tornillo, Giusy, Kendrick, Howard, Meniel, Valerie, Olijnyk-Dallis, Daria, Morris, Joanna S., Stein, Torstein, Gusterson, Barry A., Isacke, Clare M. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2017. Receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis. Development 144 (20) , pp. 3777-3788. 10.1242/dev.149120
filefilefilefilefilefile

Tang, Hiu Kwan Carolyn, Lee, Doreen Yin Hui, Thompson, Ian, Ingram, John R. ORCID: https://orcid.org/0000-0002-5257-1142, Stone, Natalie and Patel, Girish K. 2017. Delayed and localized pemphigus vulgaris after breast cancer radiotherapy. The Breast Journal 23 (6) , pp. 747-749. 10.1111/tbj.12910
file

Yeo, Syn Kok, French, Rhiannon, Filomena, Spada and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2017. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment 162 (3) , pp. 465-477. 10.1007/s10549-017-4149-0
file

2016

Abraham, Thomas, Barbier, Michaël, Jaensch, Steffen, Cornelissen, Frans, Vidic, Suzana, Gjerde, Kjersti, de Hoogt, Ronald, Graeser, Ralph, Gustin, Emmanuel, Chong, Yolanda T. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2016. Ellipsoid segmentation model for analyzing light-attenuated 3D confocal image stacks of fluorescent multi-cellular spheroids. PLoS ONE 11 (6) , e0156942. 10.1371/journal.pone.0156942
file

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Loizou, Joanna I., Bradburn, Amy, Kanu, Nnennaya, Purewal, Sukhveer, Da Costa, Clive, Bonnet, Dominique and Behrens, Axel 2016. Perturbed hematopoiesis in mice lacking ATMIN. Blood 128 (16) , pp. 2017-2021. 10.1182/blood-2015-09-672980
file

Clarke, Paul A., Ortiz-Ruiz, Maria-Jesus, TePoele, Robert, Adeniji-Popoola, Olajumoke, Box, Gary, Court, Will, Czasch, Stefanie, El Bawab, Samer, Esdar, Christina, Ewan, Ken ORCID: https://orcid.org/0000-0001-6622-9009, Gowan, Sharon, De Haven Brandon, Alexis, Hewitt, Phllip, Hobbs, Stephen M., Kaufmann, Wolfgang, Mallinger, Aurélie, Raynaud, Florence, Roe, Toby, Rohdich, Felix, Schiemann, Kai, Simon, Stephanie, Schneider, Richard, Valenti, Melanie, Weigt, Stefan, Blagg, Julian, Blaukat, Andree, Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963, Eccles, Suzanne A., Hecht, Stefan, Urbahns, Klaus, Workman, Paul and Wienke, Dirk 2016. Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases. eLife 5 , e20722. 10.7554/eLife.20722
file

Czodrowski, Paul, Mallinger, Aurélie, Wienke, Dirk, Esdar, Christina, Pöschke, Oliver, Busch, Michael, Rohdich, Felix, Eccles, Suzanne A., Ortiz-Ruiz, Maria-Jesus, Schneider, Richard, Raynaud, Florence I., Clarke, Paul A., Musil, Djordje, Schwarz, Daniel, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Urbahns, Klaus, Blagg, Julian and Schiemann, Kai 2016. Structure-based optimization of potent, selective, and orally bioavailable CDK8 inhibitors discovered by high-throughput screening. Journal of Medicinal Chemistry 59 (20) , pp. 9337-9349. 10.1021/acs.jmedchem.6b00597
file

Denoyer, Delphine, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Clatworthy, Sharnel A.S., Smith, Zoe M., Francis, Paul S., Llanos, Roxana M., Volitakis, Irene, Phillips, Wayne A., Meggyesy, Peter M., Masaldan, Shashank and Cater, Michael A. 2016. Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution. Oncotarget 7 (24) , pp. 37064-37080. 10.18632/oncotarget.9245
file

Estrada, Marta F., Rebelo, Sofia P., Davies, Emma J., Pinto, Marta T., Pereira, Hugo, Santo, Vítor E., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Barry, Simon T., Gualda, Emilio J., Alves, Paula M., Anderson, Elizabeth and Brito, Catarina 2016. Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression. Biomaterials 78 , pp. 50-61. 10.1016/j.biomaterials.2015.11.030
file

Fang, Hsiao Yu, Martinez-Arias, Alfonso and De Navascues Melero, Joaquin ORCID: https://orcid.org/0000-0002-5414-4056 2016. Autocrine and paracrine Wingless signalling in the Drosophila midgut by both continuous gradient and asynchronous bursts of wingless expression. F1000Research 5 , 317. 10.12688/f1000research.8170.1
file

Flanagan, Dustin J., Schwab, Renate H. M., Tran, Bang M., Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2016. Isolation and culture of adult intestinal, gastric, and lver organoids for cre-recombinase-mediated gene deletion. Methods in Molecular Biology, Humana Press, pp. 1-11. (10.1007/7651_2016_14)
file

Griessinger, Emmanuel, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Vargaftig, Jacques, Taussig, David C., Lassailly, Francois, Prebet, Thomas, Imbert, Veronique, Nebout, Marielle, Vey, Norbert, Chabannon, Christian, Filby, Andrew, Bollet-Quivogne, Frederic, Gribben, John G., Peyron, Jean-Francois and Bonnet, Dominique 2016. Frequency and dynamics of leukemia-initiating cells during short-term ex vivo culture informs outcomes in acute myeloid leukemia patients. Cancer Research 76 (8) , pp. 2082-2086. 10.1158/0008-5472.CAN-15-2063

Hollins, Andrew John ORCID: https://orcid.org/0000-0002-0324-9376 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2016. Long-term culture of intestinal cell progenitors: an overview of their development, application, and associated technologies. Current Pathobiology Reports 4 (4) , pp. 209-219. 10.1007/s40139-016-0119-1
file

Jardé, Thierry, Lloyd-Lewis, Bethan, Thomas, Mairian, Kendrick, Howard, Melchor, Lorenzo, Bougaret, Lauriane, Watson, Peter D., Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 2016. Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids. Nature Communications 7 , 13207. 10.1038/ncomms13207
file

Jurado, Jaime, De Navascues Melero, Joaquin ORCID: https://orcid.org/0000-0002-5414-4056 and Gorfinkiel, Nicole 2016. α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction. Journal of Cell Science , jcs.193268. 10.1242/jcs.193268
file

Mallinger, Aurélie, Schiemann, Kai, Rink, Christian, Stieber, Frank, Calderini, Michel, Crumpler, Simon, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Poeschke, Oliver, Busch, Michael, Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Ortiz-Ruiz, Maria-Jesus, Schneider, Richard, Thai, Ching, Valenti, Melanie, de Haven Brandon, Alexis, Burke, Rosemary, Workman, Paul, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Wienke, Dirk, Clarke, Paul A., Esdar, Christina, Raynaud, Florence I., Eccles, Suzanne A., Rohdich, Felix and Blagg, Julian 2016. Discovery of potent, selective, and orally bioavailable small-molecule modulators of the mediator complex-associated kinases CDK8 and CDK19. Journal of Medicinal Chemistry 59 (3) , pp. 1078-1101. 10.1021/acs.jmedchem.5b01685

Parfitt, Geraint J. ORCID: https://orcid.org/0000-0002-8704-7906, Brown, Donald J. and Jester, James V. 2016. Transcriptome analysis of aging mouse meibomian glands. Molecular Vision 22 , pp. 518-527.

Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Flanagan, Dustin and Vincan, Elizabeth 2016. Frizzled7: a promising achilles' heel for targeting the Wnt receptor complex to treat cancer. Cancers 8 (5) , p. 50. 10.3390/cancers8050050
file

Porazinski, Sean, De Navascues, Joaquin, Yako, Yuta, Hill, William, Jones, Matthew Robert, Maddison, Robert, Fujita, Yasuyuki and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2016. EphA2 drives the segregation of Ras-transformed epithelial cells from normal neighbors. Current Biology 26 (23) , pp. 3220-3229. 10.1016/j.cub.2016.09.037
file

Rebello, Richard J., Kusnadi, Eric, Cameron, Donald P., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Lesmana, Analia, Devlin, Jennifer R., Drygin, Denis, Clark, Ashlee K., Porter, Laura, Pedersen, John, Sandhu, Shahneen, Risbridger, Gail P., Pearson, Richard B. ORCID: https://orcid.org/0000-0002-3284-0843, Hannan, Ross D. and Furic, Luc 2016. The dual inhibition of RNA Pol I transcription and PIM kinase as a new therapeutic approach to treat advanced prostate cancer. Clinical Cancer Research 22 (22) , pp. 5539-5552. 10.1158/1078-0432.CCR-16-0124
file

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Song, Fei, Young, Madeleine, Hassan, N., Antoine, A. J., Gemici, Nesibe-Princess B, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Jenkins, J. R. 2016. Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. Oncotarget 7 (32) , pp. 51665-51673. 10.18632/oncotarget.10076
file

Reza, Mariana, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Aspegren, John, Massard, Christophe, Mattila, Leena, Mustonen, Mika, Wollmer, Per, Trägårdh, Elin, Bondesson, Eva, Edenbrandt, Lars, Fizazi, Karim and Bjartell, Anders 2016. Bone scan index and progression-free survival data for progressive metastatic castration-resistant prostate cancer patients who received ODM-201 in the ARADES multicentre study. European Urology Focus 2 (5) , pp. 547-552. 10.1016/j.euf.2016.01.005
file

Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R. and Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X 2016. Epigenetic silencing of serine protease HTRA1 drives polyploidy. BMC Cancer 16 , 399. 10.1186/s12885-016-2425-8
file

Togel, L., Nightingale, R.-, Chueh, A.. C., Jayachandran, A., Tran, Huynh, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Wu, R., Sieber, O. M., Arango, D., Dhillon, A. S., Dawson, M. A., Diez-Dacal, B., Gahman, T. C., Filippakopoulos, P., Shiau, A. K. and Mariadason, J. M. 2016. Dual targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Molecular Cancer Therapeutics 15 (6) , pp. 1217-1226. 10.1158/1535-7163.MCT-15-0724

Turingan, Rosemary S., Vasantgadkar, Sameer, Palombo, Luke, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Jiang, Hua, Tan, Eugene and Selden, Richard F. 2016. Rapid DNA analysis for automated processing and interpretation of low DNA content samples. Investigative Genetics 7 (1) , 2. 10.1186/s13323-016-0033-7
file

Yeo, Syn Kok, Ali, Ahmed Y., Hayward, Olivia A., Turnham, Daniel, Jackson, Troy, Bowen, Ifor D. and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2016. Bisabolene, a sesquiterpene from the essential oil extract of opoponax (Commiphora guidottii), exhibits cytotoxicity in breast cancer cell lines. Phytotherapy Research 30 (3) , pp. 418-425. 10.1002/ptr.5543
file

Zhao, Chuntao, Deng, Yaqi, Liu, Lei, Yu, Kun, Zhang, Liguo, Wang, Haibo, He, Xuelian, Wang, Jincheng, Lu, Changqing, Wu, Laiman N, Weng, Qinjie, Mao, Meng, Li, Jianrong, van Es, Johan H, Xin, Mei, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Goldman, Steven A, Clevers, Hans and Lu, Q. Richard 2016. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nature Communications 7 , 10883. 10.1038/ncomms10883
file

2015

Ali, Ahmed Y., Yeo, Syn, Ellis, Sadie, Ade, Jamilla, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Esa, Adam, Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254, Bowen, Ifor D. and Martin, Tracey A. ORCID: https://orcid.org/0000-0003-2690-4908 2015. Anti-metastatic and cytotoxic properties of frankincense and scented myrrh. Anticancer Research 35 (7) , pp. 4310-4311.

Costello, Patrick, Sargent, Mathew, Maurice, Diane, Esnault, Cyril, Foster, Katie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Treisman, Richard 2015. MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development. Blood 125 (8) , pp. 1244-1255. 10.1182/blood-2014-08-595603

Dale, Trevor ORCID: https://orcid.org/0000-0002-4880-9963, Clarke, Paul A., Esdar, Christina, Waalboer, Dennis, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Mallinger, Aurélie, Samant, Rahul S., Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Schneider, Klaus, Stubbs, Mark, Ewan, Ken ORCID: https://orcid.org/0000-0001-6622-9009, Fraser, Elizabeth, TePoele, Robert, Court, Will, Box, Gary, Valenti, Melanie, de Haven Brandon, Alexis, Gowan, Sharon, Rohdich, Felix, Raynaud, Florence, Schneider, Richard, Poeschke, Oliver, Blaukat, Andree, Workman, Paul, Schiemann, Kai, Eccles, Suzanne A., Wienke, Dirk and Blagg, Julian 2015. A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease. Nature Chemical Biology 11 , pp. 973-980. 10.1038/nchembio.1952

Ferrari, Nicola, Riggio, Alessandra I., Mason, Susan, McDonald, Laura, King, Ayala, Higgins, Theresa, Rosewell, Ian, Neil, James C., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Sansom, Owen J., Morris, Joanna, Cameron, Ewan R. and Blyth, Karen 2015. Runx2 contributes to the regenerative potential of the mammary epithelium. Scientific Reports 5 , 15658. 10.1038/srep15658
file

Flanagan, Dustin J., Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Barker, Nick, Schwab, Renate H. M., Amin, Nancy, Malaterre, Jordane, Stange, Daniel E., Nowell, Cameron J., Currie, Scott A., Saw, Jarel T. S., Beuchert, Eva, Ramsay, Robert G., Sansom, Owen J., Ernst, Matthias, Clevers, Hans and Vincan, Elizabeth 2015. Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells. Stem Cell Reports 4 (5) , pp. 759-767. 10.1016/j.stemcr.2015.03.003
file

Foster, Katie, Lassailly, François, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Currie, Erin, Rouault-Pierre, Kevin and Bonnet, Dominique 2015. Different motile behaviors of human hematopoietic stem versus progenitor cells at the osteoblastic niche. Stem Cell Reports 5 (5) , pp. 690-701. 10.1016/j.stemcr.2015.09.003
file

Francis, Jeffrey C., Melchor, Lorenzo, Campbell, James, Kendrick, Howard, Wei, Wenbin, Armisen-Garrido, Javier, Assiotis, Ioannis, Chen, Lina, Kozarewa, Iwanka, Fenwick, Kerry, Swain, Amanda, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Lord, Christopher J. and Ashworth, Alan 2015. Whole exome DNA sequence analysis of Brca2 and Trp53 deficient mouse mammary gland tumours. Journal of Pathology 236 (2) , pp. 186-200. 10.1002/path.4517
file

Freeman, Jamie, Smith, David, Latinkic, Branko ORCID: https://orcid.org/0000-0003-4952-123X, Ewan, Ken ORCID: https://orcid.org/0000-0001-6622-9009, Samuel, Lee, Zollo, Massimo, Marino, Natascia, Tyas, Lorraine, Jones, Nick and Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 2015. A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. Molecular Cancer 14 , 206. 10.1186/s12943-015-0475-1
file

French, Rhiannon, Hayward, Olivia, Jones, Samuel, Yang, William and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2015. Cytoplasmic levels of cFLIP determine a broad susceptibility of breast cancer stem/progenitor-like cells to TRAIL. Molecular Cancer 14 , 209. 10.1186/s12943-015-0478-y
file

Greenow, Kirsty Rhian and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2015. Overview of genetically engineered mouse models of breast cancer used in translational biology and drug development. Current Protocols in Pharmacology 70 (1) , 70:14.36.1-14.36.14.. 10.1002/0471141755.ph1436s70

Hiom, S., Khot, S. ORCID: https://orcid.org/0000-0003-4677-5680, Mogford, S., Hart, C., Patel, G., Roberts, G., Matin, C. and Newcombe, R. 2015. Topical delivery of gabapentin (Gaba Gel™) for neuropathic pain: a proof of concept study. Presented at: Royal Pharmaceutical Society Annual Conference 2015, Birmingham, England, 13-14 September 2015. International Journal of Pharmacy Practice. , vol.23 (S2) Royal Pharmaceutical Society of Great Britain, pp. 46-47. 10.1111/ijpp.12213

Hiom, S., Patel, Girish Khandubhai, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867, Khot, S. and Martin, C. 2015. Severe postherpetic neuralgia and other neuropathic pain syndromes alleviated by topical gabapentin. British Journal of Dermatology 173 (1) , pp. 300-302. 10.1111/bjd.13624

Hiom, Sarah, Patel, Girish, Newcombe, Robert ORCID: https://orcid.org/0000-0003-4400-8867 and Khot, Sharmila ORCID: https://orcid.org/0000-0003-4677-5680 2015. Severe postherpetic neuralgia and other neuropathic pain syndromes alleviated by topical gabapentin. British Journal of Dermatology 173 (1) , pp. 300-302. 10.1111/bjd.13624

Huels, David J., Ridgway, Rachel A., Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D., Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie S., Maguire, Aoife, Doyle, Brendan, Soderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. 2015. E-cadherin can limit the transforming properties of activating β‐catenin mutations. EMBO Journal 34 (18) , pp. 2321-2333. 10.15252/embj.201591739
file

Iglesias, Juan Manuel, Cairney, Claire J., Ferrier, Roderick K., McDonald, Laura, Soady, Kelly, Kendrick, Howard, Pringle, Marie-Anne, Morgan, Reginald O., Martin, Finian, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Blyth, Karen and Stein, Torsten 2015. Annexin A8 identifies a subpopulation of transiently quiescent c-Kit positive luminal progenitor cells of the ductal mammary epithelium. Plos One 10 (3) , e0119718. 10.1371/journal.pone.0119718
file

Jester, James V., Parfitt, Geraint J ORCID: https://orcid.org/0000-0002-8704-7906 and Brown, Donald J. 2015. Meibomian gland dysfunction: hyperkeratinization or atrophy? BMC Ophthalmology 15 (S1) , 156. 10.1186/s12886-015-0132-x

Johnstone, C. N., Smith, Y. E., Cao, Y., Burrows, A. D., Cross, R. S. N., Ling, X., Redvers, R. P., Doherty, J. P., Eckhardt, B. L., Natoli, A. L., Restall, C. M., Lucas, E., Pearson, H. B. ORCID: https://orcid.org/0000-0002-3284-0843, Deb, S., Britt, K. L., Rizzitelli, A., Li, J., Harmey, J. H., Pouliot, N. and Anderson, R. L. 2015. Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer. Disease Models and Mechanisms 8 (3) , pp. 237-251. 10.1242/dmm.017830
file

Kahlert, Ulf D., Suwala, Abigail K., Raabe, Eric H., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Suarez, Maria J., Orr, Brent A., Bar, Eli E., Maciaczyk, Jaroslaw and Eberhart, Charles G. 2015. ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres. Brain Pathology 25 (6) , pp. 724-732. 10.1111/bpa.12240

Leal, Maria del Pilar Camacho, Sciortino, Marianna, Tornillo, Giusy, Colombo, Shana, Defilippi, Paola and Cabodi, Sara 2015. p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis. Gene 562 (1) , pp. 1-7. 10.1016/j.gene.2015.02.027

Lio, Ka Ian 2015. Characterising the role of Cbx3/HP1γ in normal intestinal homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Mallinger, Aurélie, Crumpler, Simon, Pichowicz, Mark, Waalboer, Dennis, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Wood, Bozena, Smith, Elizabeth, Thai, Ching, Henley, Alan T., Georgi, Katrin, Court, William, Hobbs, Steve, Box, Gary, Ortiz-Ruiz, Maria-Jesus, Valenti, Melanie, De Haven Brandon, Alexis, TePoele, Robert, Leuthner, Birgitta, Workman, Paul, Aherne, Wynne, Poeschke, Oliver, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Wienke, Dirk, Esdar, Christina, Rohdich, Felix, Raynaud, Florence, Clarke, Paul A., Eccles, Suzanne A., Stieber, Frank, Schiemann, Kai and Blagg, Julian 2015. Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen. Journal of Medicinal Chemistry 58 (4) , pp. 1717-1735. 10.1021/jm501436m

Meniel, Valerie, Megges, M., Young, Madeleine, Cole, A., Sansom, O. J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Apc and p53 interaction in DNA damage and genomic instability in hepatocytes. Oncogene 34 , pp. 4118-4129. 10.1038/onc.2014.342

Miraki-Moud, Farideh, Ghazaly, Essam, Ariza-McNaughton, Linda, Hodby, Katharine A., Clear, Andrew, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Liapis, Konstantinos, Grantham, Marianne, Sohrabi, Fareeda, Cavenagh, Jamie, Bomalaski, John S., Gribben, John G., Szlosarek, Peter W., Bonnet, Dominique and Taussig, David C. 2015. Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo. Blood 125 (26) , pp. 4060-4068. 10.1182/blood-2014-10-608133

Niavarani, Ahmadreza, Currie, Erin, Reyal, Yasmin, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Horswell, Stuart, Griessinger, Emmanuel, Luis Sardina, Jose and Bonnet, Dominique 2015. APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts. PLoS ONE 10 (3) , e0120089. 10.1371/journal.pone.0120089
file

Parfitt, Geraint J ORCID: https://orcid.org/0000-0002-8704-7906, Geyfman, Mikhail, Xie, Yilu and Jester, James V. 2015. Characterization of quiescent epithelial cells in mouse meibomian glands and hair follicle/sebaceous glands by immunofluorescence tomography. Journal of Investigative Dermatology 135 (4) , pp. 1175-1177. 10.1038/jid.2014.484

Parfitt, Geraint J ORCID: https://orcid.org/0000-0002-8704-7906, Kavianpour, Behdad, Wu, Karen L., Xie, Yilu, Brown, Donald J. and Jester, James V. 2015. Immunofluorescence tomography of mouse ocular surface epithelial stem cells and their niche microenvironment. Investigative Ophthalmology & Visual Science 56 (12) , p. 7338. 10.1167/iovs.15-18038

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Protocols for analyzing the role of Paneth cells in regenerating the murine intestine using conditional cre-lox mouse models. Journal of Visualized Experiments (105) , e53429. 10.3791/53429
file

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, McGlinn, Edwina, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Schlüter, Holger, Srikumar, Anuratha, Gödde, Nathan J., Woelwer, Christina B., Ryan, Andrew, Phillips, Wayne A., Ernst, Matthias, Kaur, Pritinder and Humbert, Patrick 2015. The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Molecular Cancer 14 , 169. 10.1186/s12943-015-0440-z
file

Piggott, Luke, Omidvar, Nader, Martí Pérez, Salvador, French, Rhiannon, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2015. Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 17 (1) , p. 96. 10.1186/s13058-015-0597-9
file

Rada, Patricia, Rojo, Ana I., Offergeld, Anika ORCID: https://orcid.org/0000-0001-8916-2505, Feng, Gui Jie, Velasco-Martín, Juan P., González-Sancho, José Manuel, Valverde, Ángela M., Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Regadera, Javier and Cuadrado, Antonio 2015. WNT-3A regulates an Axin1/NRF2 complex that regulates antioxidant metabolism in hepatocytes. Antioxidants & Redox Signaling 22 (7) , pp. 555-571. 10.1089/ars.2014.6040
file

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Athineos, Dimitris, Meniel, Valerie, Wilkins, Julie A., Ridgway, Rachel A., Burke, Zoe D., Muncan, Vanessa, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. 2015. Correction for Reed et al., B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 112 (10) , E1168. 10.1073/pnas.1502294112

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Korobko, Igor, Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Korobko, Elena V., Hopkins, Ben R., Platt, James L., Buchman, Vladimir ORCID: https://orcid.org/0000-0002-7631-8352 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Hunk/Mak-v is a negative regulator of intestinal cell proliferation. BMC Cancer 15 , 110. 10.1186/s12885-015-1087-2
file

Sampurno, Shienny, Cross, Ryan, Pearson, Helen ORCID: https://orcid.org/0000-0002-3284-0843, Kaur, Pritinder, Malaterre, Jordane and Ramsay, Robert G. 2015. Myb via TGFβ is required for collagen type 1 production and skin integrity. Growth Factors 33 (2) , pp. 102-112. 10.3109/08977194.2015.1016222

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 2015. Application of an RNA amplification method for reliable single-cell transcriptome analysis. Biotechniques 59 (3) , pp. 137-148. 10.2144/000114331

Soady, Kelly J., Kendrick, Howard, Gao, Qiong, Tutt, Andrew, Zvelebil, Marketa, Ordonez, Liliana D., Quist, Jelmar, Tan, David Wei-Min, Isacke, Clare M., Grigoriadis, Anita and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2015. Mouse mammary stem cells express prognostic markers for triple-negative breast cancer. Breast Cancer Research 17 , 31. 10.1186/s13058-015-0539-6
file

Takizawa, Itsuhiro, Lawrence, Mitchell G., Balanathan, Preetika, Rebello, Richard, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Garg, Elika, Pedersen, John, Pouliot, Normand, Nadon, Robert, Watt, Matthew J., Taylor, Renea A., Humbert, Patrick, Topisirovic, Ivan, Larsson, Ola, Risbridger, Gail P. and Furic, Luc 2015. Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity. Oncotarget 6 (2) , pp. 604-616. 10.18632/oncotarget.2820
file

Tangudu, N. K., Verma, V. K., Clemons, T. D., Beevi, S. S., Hay, Trevor, Mahidhara, G., Raja, Meera, Nair, R. A., Alexander, L. E., Patel, A. B., Jose, J., Smith, N. M., Zdyrko, B., Bourdoncle, A., Luzinov, I., Iyer, K. S., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dinesh Kumar, L. 2015. RNA interference using c-Myc-conjugated nanoparticles suppresses breast and colorectal cancer models. Molecular Cancer Therapeutics 14 (5) , pp. 1259-1269. 10.1158/1535-7163.MCT-14-0970

Tornillo, Giusy and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2015. ERrrr...Where are the progenitors? Hormone receptors and mammary cell heterogeneity. Journal of Mammary Gland Biology and Neoplasia 20 (1) , pp. 63-73. 10.1007/s10911-015-9336-1
file

Wölwer, Christina B., Pase, Luke B., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Gödde, Nathan J., Lackovic, Kurt, Huang, David C. S., Russell, Sarah M. and Humbert, Patrick O. 2015. A chemical screening approach to identify novel key mediators of erythroid enucleation. PLoS ONE 10 (11) , e0142655. 10.1371/journal.pone.0142655
file

2014

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2014. Forgotten gems. Cell Cycle 13 (4) , pp. 503-504. 10.4161/cc.27788

Carotenuto, M., De Antonellis, P., Liguori, L., Benvenuto, G., Magliulo, D., Alonzi, A., Turino, C., Attanasio, C., Damiani, V., Bello, A. M., Vitiello, F., Pasquinelli, R., Terracciano, L., Federico, A., Fusco, A., Freeman, Jamie, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Decraene, C., Chiappetta, G., Piantedosi, F., Calabrese, C. and Zollo, M. 2014. H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC. Oncotarget 5 (14) , pp. 5736-5749. 10.18632/oncotarget.2169
file

Cowley, Michael, Garfield, Alastair S., Madon-Simon, Marta, Charalambous, Marika, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Kendrick, Howard, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Parry, Aled J., Carney, Sara, Oakey, Rebecca J., Heisler, Lora K., Moorwood, Kim, Wolf, Jason B. and Ward, Andrew 2014. Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup. PLoS Biology 12 (2) , e1001799. 10.1371/journal.pbio.1001799
file

Davies, Emma Jane, Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Meniel, Valerie, Williams, Geraint Trfor ORCID: https://orcid.org/0000-0003-3768-9940 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2014. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine. The Journal of Pathology 233 (1) , pp. 27-38. 10.1002/path.4312

de Groot, Reinoud E. A., Ganji, Ranjani S., Bernatik, Ondrej, Lloyd-Lewis, Bethan, Seipel, Katja, Šedova, Katerina, Zdrahal, Zbynek, Dhople, Vishnu M., Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963, Korswagen, Hendrik C. and Bryja, Vitezslav 2014. Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway. Science Signaling 7 (317) , ra26. 10.1126/scisignal.2004985

DiTommaso, Tia, Cottle, Denny L., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Schlüter, Holger, Kaur, Pritinder, Humbert, Patrick O. and Smyth, Ian M. 2014. Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genetics 10 (10) , e1004706. 10.1371/journal.pgen.1004706
file

Elsum, I. A., Yates, L. L., Pearson, H. B. ORCID: https://orcid.org/0000-0002-3284-0843, Phesse, T. J. ORCID: https://orcid.org/0000-0001-9568-4916, Long, F., O'Donoghue, R., Ernst, M., Cullinane, C. and Humbert, P. O. 2014. Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo. Oncogene 33 (48) , pp. 5523-5533. 10.1038/onc.2013.498

Fizazi, Karim, Massard, Christophe, Bono, Petri, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Kataja, Vesa, James, Nicholas, Garcia, Jorge A., Protheroe, Andrew, Tammela, Teuvo L., Elliott, Tony, Mattila, Leena, Aspegren, John, Vuorela, Annamari, Langmuir, Peter and Mustonen, Mika 2014. Activity and safety of ODM-201 in patients with progressive metastatic castration-resistant prostate cancer (ARADES): an open-label phase 1 dose-escalation and randomised phase 2 dose expansion trial. Lancet Oncology 15 (9) , pp. 975-985. 10.1016/S1470-2045(14)70240-2
file

Godde, Nathan J., Sheridan, Julie M., Smith, Lorey K., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Britt, Kara L., Galea, Ryan C., Yates, Laura L., Visvader, Jane E. and Humbert, Patrick O. 2014. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genetics 10 (5) , e1004323. 10.1371/journal.pgen.1004323
file

Gödde, Nathan J, Pearson, Helen B ORCID: https://orcid.org/0000-0002-3284-0843, Smith, Lorey K and Humbert, Patrick O 2014. Dissecting the role of polarity regulators in cancer through the use of mouse models. Experimental Cell Research 328 (2) , pp. 249-257. 10.1016/j.yexcr.2014.08.036

Greenow, K. R., Clarke, A. R. ORCID: https://orcid.org/0000-0002-4281-426X, Williams, G. T. ORCID: https://orcid.org/0000-0003-3768-9940 and Jones, R. ORCID: https://orcid.org/0000-0003-3576-9496 2014. Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency. Oncogene 33 , pp. 4089-4096. 10.1038/onc.2013.371

Griessinger, E., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Pizzitola, I., Rouault-Pierre, K., Vargaftig, J., Taussig, D., Gribben, J., Lassailly, F. and Bonnet, Dominique 2014. A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: A new tool to decipher their chemoresistance and self-renewal mechanisms. Stem Cells Translational Medicine 3 (4) , pp. 520-529. 10.5966/sctm.2013-0166
file

Hare, Lauren M., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Waring, Paul M., Montgomery, Karen G., Kinross, Kathryn M., Mills, Kevin, Roh, Vincent, Heath, Joan K., Ramsay, Robert G., Ernst, Matthias and Phillips, Wayne A. 2014. Physiological expression of the PI3K-activating mutationPik3caH1047Rcombines withApcloss to promote development of invasive intestinal adenocarcinomas in mice. Biochemical Journal 458 (2) , pp. 251-258. 10.1042/BJ20131412

Hickman, John A., Graeser, Ralph, de Hoogt, Ronald, Vidic, Suzana, Brito, Catarina, Gutekunst, Matthias, van der Kuip, Heiko, consortium, IMI PREDECT and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2014. Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo. Biotechnology Journal 9 (9) , pp. 1115-1128. 10.1002/biot.201300492

Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Metzger, Daniel, Shorning, Boris Y. and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453
file

Infantino, S., Jones, S. A., Walker, J. A., Maxwell, M. J., Light, A., O'Donnell, K., Tsantikos, E., Peperzak, V., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Ernst, M., Mackay, F., Hibbs, M. L., Fairfax, K. A. and Tarlinton, D. M. 2014. The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice. Science Signaling 7 (338) , ra77. 10.1126/scisignal.2005105

Khurana, Rimpi, Verma, Vinod, Rawoof, Abdul, Tiwari, Shrish, Nair, Rekha A., Mahidhara, Ganesh, Idris, Mohammed M., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Kumar, Lekha 2014. OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer. BMC Bioinformatics 15 (1) , p. 15. 10.1186/1471-2105-15-15
file

Koh, D. -I., Han, D., Ryu, H., Choi, W.-I., Jeon, B. -N., Kim, M. -K., Kim, Y., Kim, J. Y., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Reynolds, A. B. and Hur, M. -W. 2014. KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Proceedings of the National Academy of Sciences of the United States of America 111 (42) , pp. 15078-15083. 10.1073/pnas.1318780111

Krzystyniak, Joanna 2014. Epigenetic modulation of intestinal homeostasis and tumorigenesis by Brm SWI/SNF chromatin remodelling factor. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Jansen, Marnix, Davies, Emma Jane, Morsink, Folkert H., Offerhaus, G. Johan A. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2014. Epithelial-specific loss of PTEN results in colorectal juvenile polyp formation and invasive cancer. American Journal of Pathology 184 (1) , pp. 86-91. 10.1016/j.ajpath.2013.10.003

Melchor, Lorenzo, Molyneux, Gemma, Mackay, Alan, Magnay, Fiona-Ann, Atienza, María, Kendrick, Howard, Nava-Rodrigues, Daniel, López-García, María Ángeles, Milanezi, Fernanda, Greenow, Kirsty, Robertson, David, Palacios, José, Reis-Filho, Jorge S. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2014. Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models. Journal of Pathology 233 (2) , pp. 124-137. 10.1002/path.4345
filefilefilefilefilefilefile

Phesse, T. J. ORCID: https://orcid.org/0000-0001-9568-4916, Myant, K. B., Cole, A. M., Ridgway, R. A., Pearson, H. ORCID: https://orcid.org/0000-0002-3284-0843, Muncan, V., van den Brink, G. R., Vousden, K. H., Sears, R., Vassilev, L . T ., Clarke, A. R. ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, O. J. 2014. Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo. Cell Death and Differentiation 21 (6) , pp. 956-966. 10.1038/cdd.2014.15
file

Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Buchert, Michael, Stuart, Emma, Flanagan, Dustin J., Faux, Maree, Afshar-Sterle, Shoukat, Walker, Francesca, Zhang, Hui-Hua, Nowell, Cameron J., Jorissen, Robert, Tan, Chin Wee, Hirokawa, Yumiko, Eissmann, Moritz F., Poh, Ashleigh R., Malaterre, Jordane, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Kirsch, David G., Provero, Paolo, Poli, Valeria, Ramsay, Robert G., Sieber, Oliver, Burgess, Antony W., Huszar, Dennis, Vincan, Elizabeth and Ernst, Matthias 2014. Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration. Science Signaling 7 (345) , ra92. 10.1126/scisignal.2005411

Pizzitola, I., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Rouault-Pierre, K., Lassailly, F., Tettamanti, S., Spinelli, O., Biondi, A., Biagi, E. and Bonnet, D. 2014. Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo. Leukemia 28 , pp. 1596-1605. 10.1038/leu.2014.62

Rickard, James A., O'Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti and Silke, John 2014. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 157 (5) , pp. 1175-1188. 10.1016/j.cell.2014.04.019

Rudge, Felicity and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2014. Therapeutic targeting of the Wnt signaling network. Hoppler, Stefan P. and Moon, Randall T., eds. Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions, John Wiley & Sons, pp. 421-443.

Sarkisian, Matthew R., Siebzehnrubl, Dorit, Hoang-Minh, Lan, Deleyrolle, Loic, Silver, Daniel J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Guadiana, Sarah M., Srivinasan, Gayathri, Semple-Rowland, Susan, Harrison, Jeffrey K., Steindler, Dennis A. and Reynolds, Brent A. 2014. Detection of primary cilia in human glioblastoma. Journal of Neuro-Oncology 117 (1) , pp. 15-24. 10.1007/s11060-013-1340-y

Stuart, E., Buchert, M., Putoczki, T., Thiem, S., Farid, R., Elzer, J., Huszar, D., Waring, P. M., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Ernst, M. 2014. Therapeutic inhibition of jak activity inhibits progression of gastrointestinal tumors in mice. Molecular Cancer Therapeutics 13 (2) , p. 468. 10.1158/1535-7163.MCT-13-0583-T

Suhalim, Jeffrey L., Parfitt, Geraint J ORCID: https://orcid.org/0000-0002-8704-7906, Xie, Yilu, De Paiva, Cintia S., Pflugfelder, Stephen C., Shah, Tejas N., Potma, Eric O., Brown, Donald J. and Jester, James V. 2014. Effect of desiccating stress on mouse meibomian gland function. Ocular Surface 12 (1) , pp. 59-68. 10.1016/j.jtos.2013.08.002

Tanguay, J. S., Wheeler, P., Button, M., Stevens, R., Shaw, Paul ORCID: https://orcid.org/0000-0002-7467-0619, Brewster, A., Hanna, L. and Lester, J. F. 2014. Limited stage small cell lung cancer (LS SCLC) South East Wales experience. Lung Cancer 88 (Supp 1) , S66. 10.1016/S0169-5002(14)70180-1

Tornillo, Giusy and Cabodi, Sara 2014. 3D mammary colony-forming cell assay. Bio-Protocol 4 (7)

Vedam-Mai, Vinata, Gardner, Bronwen, Okun, Michael S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kam, Monica, Aponso, Palingu, Steindler, Dennis A., Yachnis, Anthony T., Neal, Dan, Oliver, Brittany U., Rath, Sean J., Faull, Richard L. M., Reynolds, Brent A. and Curtis, Maurice A. 2014. Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study. PLoS ONE 9 (3) , e88770. 10.1371/journal.pone.0088770
file

2013

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Currie, Erin, Palmer, Hector G., Foster, Katie E., Taussig, David C. and Bonnet, Dominique 2013. CD34− cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures. Cell Stem Cell 13 (2) , pp. 161-174. 10.1016/j.stem.2013.05.025

Bhatti, H., Basra, M. and Patel, Girish Khandubhai 2013. Hair restoration approaches for early onset male androgenetic alopecia. Journal of Cosmetic Dermatology 12 (3) , pp. 223-231. 10.1111/jocd.12047

Cater, Michael A., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Wolyniec, Kamil, Klaver, Paul, Bilandzic, Maree, Paterson, Brett M., Bush, Ashley I., Humbert, Patrick O., La Fontaine, Sharon, Donnelly, Paul S. and Haupt, Ygal 2013. Increasing intracellular bioavailable copper selectively targets prostate cancer cells. ACS Chemical Biology 8 (7) , pp. 1621-1631. 10.1021/cb400198p

Colmont, Chantal Sophie, Ben Ketah, Antisar, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Reed, Simon Huw ORCID: https://orcid.org/0000-0002-4711-0560, Udey, Mark C. and Patel, Girish Khandubai 2013. Human basal cell carcinoma tumor-initiating cells are resistant to etoposide [Letter]. Journal of Investigative Dermatology 134 (3) , pp. 867-870. 10.1038/jid.2013.377

Colmont, Chantal Sophie, Ben Ketah, Antisar, Reed, Simon Huw ORCID: https://orcid.org/0000-0002-4711-0560, Hawk, Nga V., Telford, William G., Ohyama, Manabu, Udeye, Mark C., Yee, Carole L., Vogel, Jonathan C. and Patel, Girish Khandubhai 2013. CD200-expressing human basal cell carcinoma cells initiate tumor growth. Proceedings of the National Academy of Sciences of the United States of America 110 (4) , pp. 1434-1439. 10.1073/pnas.1211655110

Daly, Carl S. 2013. The roles of the APC proteins in homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Eccles, Suzanne A., Aboagye, Eric O., Ali, Simak, Anderson, Annie S., Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P., Brennan, Keith, Brown, Nicola J., Bryant, Helen E., Bundred, Nigel J., Burchell, Joy M., Campbell, Anna M., Carroll, Jason S., Clarke, Robert B., Coles, Charlotte E., Cook, Gary J. R., Cox, Angela, Curtin, Nicola J., Dekker, Lodewijk V., dos Santos Silva, Isabel, Duffy, Stephen W., Easton, Douglas F., Eccles, Diana M., Edwards, Dylan R., Edwards, Joanne, Evans, D. Gareth, Fenlon, Deborah F., Flanagan, James M., Foster, Claire, Gallagher, William M., Garcia-Closas, Montserrat, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Gescher, Andy J., Goh, Vicky, Groves, Ashley M., Harvey, Amanda J., Harvie, Michelle, Hennessy, Bryan T., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Holen, Ingunn, Howell, Sacha J., Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S., Jasani, Bharat, Jones, Louise J., Key, Timothy J., Kirwan, Cliona C., Kong, Anthony, Kunkler, Ian H., Langdon, Simon P., Leach, Martin O., Mann, David J., Marshall, John F., Martin, Lesley, Martin, Stewart G., Macdougall, Jennifer E., Miles, David W., Miller, William R., Morris, Joanna R., Moss, Sue M., Mullan, Paul, Natrajan, Rachel, O'Connor, James P. B., O'Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D. P., Rakha, Emad A., Reed, Elizabeth, Robinson, Simon P., Sahai, Erik, Saxton, John M., Schmid, Peter, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H., Tutt, Andrew N. J., Velikova, Galina, Walker, Rosemary A., Watson, Christine J., Williams, Kaye J., Young, Leonie S. and Thompson, Alastair M. 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research 15 (5) , R92. 10.1186/bcr3493
file

Gastaldi, S., Sassi, F., Accornero, P., Torti, D., Galimi, F., Migliardi, G., Molyneux, G., Perera, T., Comoglio, P. M., Boccaccio, C, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Bertotti, A. and Trusolino, L. 2013. Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer. Oncogene 32 , pp. 1428-1440. 10.1038/onc.2012.154

Guha, Prajna, Morgan, John W., Mostoslavsky, Gustavo, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733 and Boyd, Ashleigh S. 2013. Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell 12 (4) , pp. 407-412. 10.1016/j.stem.2013.01.006

Gui, Liming and Homer, Hayden 2013. Hec1-dependent cyclin B2 stabilization regulates the G2-M transition and early prometaphase in mouse oocytes. Developmental Cell 25 (1) , pp. 43-54. 10.1016/j.devcel.2013.02.008

Hammoudi, Abeer, Song, Fei, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Jenkins, Rosalind E., Meniel, Valerie, Watson, Alastair J. M., Pritchard, D. Mark, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Jenkins, John R. 2013. Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC). Biochemical and Biophysical Research Communications 440 (3) , pp. 364-370. 10.1016/j.bbrc.2013.08.076

Holik, Aliaksei, Krzystyniak, Joanna, Young, Madeleine, Richardson, Kirsty, Jarde, Thierry, Chambon, Pierre, Shorning, Boris and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner. Stem Cells 31 (11) , pp. 2457-2466. 10.1002/stem.1498

Jaganathan, Bithiah, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Kumar, Atul and Bonnet, Dominique 2013. Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche. Journal of Biomedical Science 20 (1) , 66. 10.1186/1423-0127-20-66

Jarde, Thierry, Evans, Rebecca Jane, McQuillan, Karina, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Feng, Gui Jie, Alvares, B., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2013. In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system. Oncogene 32 (7) , pp. 883-893. 10.1038/onc.2012.103

Lloyd-Lewis, Bethan, Fletcher, Alexander G., Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Byrne, Helen M. 2013. Toward a quantitative understanding of the Wnt/β-catenin pathway through simulation and experiment. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 5 (4) , pp. 391-407. 10.1002/wsbm.1221

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Davies, Emma Jane, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. PTEN loss and KRAS activation cooperate in murine biliary tract malignancies. The Journal of Pathology 230 (2) , pp. 165-173. 10.1002/path.4189

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Deuker, Marian M., Bosenberg, Marcus W., Phillips, Wayne and McMahon, Martin 2013. Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma. The Journal of Clinical Investigation 123 (12) , pp. 5104-5118. 10.1172/JCI69619

Meniel, Valerie, Song, Fei, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Young, Madeleine, Poetz, Oliver, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Jenkins, John R., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Dunwoodie, Sally L., Watson, Alastair and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Cited1 deficiency suppresses intestinal tumorigenesis. PLoS Genetics 9 (8) , e1003638. 10.1371/journal.pgen.1003638
file

Miraki-Moud, F., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Hodby, K. A., Griessinger, E., Rosignoli, G., Lillington, D., Jia, L., Davies, J. K., Cavenagh, J., Smith, M., Oakervee, H., Agrawal, S., Gribben, J. G., Bonnet, Dominique and Taussig, D. C. 2013. Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation. Proceedings of the National Academy of Sciences of the United States of America 110 (33) , pp. 13576-13581. 10.1073/pnas.1301891110

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Evidence for a crucial role of Paneth Cells in mediating the intestinal response to injury. Stem Cells 31 (4) , pp. 776-785. 10.1002/stem.1326
file

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2013. Modelling metastasis in vivo. Madame Curie Bioscience Database, Georgetown TX: Landes Bioscience,

Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Sansom, Owen J. 2013. Responding to R-spondin: slit2 potentiates intestinal regeneration. Cell Stem Cell 13 , pp. 512-514. 10.1016/j.stem.2013.10.006
file

Pouliot, Normand, Pearson, Helen ORCID: https://orcid.org/0000-0002-3284-0843 and Burrows, Allan 2013. Investigating metastasis using in vitro platforms. Madame Curie Bioscience Database, Georgetown TX: Landes Bioscience,

Raja, Meera 2013. Using GEMMs to investigate novel therapeutic strategies for colorectal cancer. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Regan, Joseph L., Sourisseau, Tony, Soady, Kelly, Kendrick, Howard, McCarthy, Afshan, Tang, Chan, Brennan, Keith, Linardopoulos, Spiros, White, Donald E. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2013. Aurora A kinase regulates mammary epithelial cell fate by determining mitotic spindle orientation in a Notch-dependent manner. Cell Reports 4 (1) , pp. 110-123. 10.1016/j.celrep.2013.05.044
file

Riris, Solon, Cawood, Suzanne, Gui, Liming, Serhal, Paul and Homer, Hayden A. 2013. Immunofluorescence staining of spindles, chromosomes, and kinetochores in human oocytes. Homer, Hayden A., ed. Mammalian Oocyte Regulation: Methods and Protocols, Methods in Molecular Biology, vol. 957. New York: Humana Press, pp. 179-187. (10.1007/978-1-62703-191-2_12)

Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733 and Tipping, A. J. 2013. Transcription factor GATA-2 regulates quiescence of hematopoietic stem and progenitor cells. Hayat, M. A., ed. Tumor Dormancy, Quiescence, and Senescence, Volume 2, Vol. 2. Springer, pp. 277-288. (10.1007/978-94-007-7726-2_26)

Rouault-Pierre, Kevin, Lopez-Onieva, Lourdes, Foster, Katie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Lamrissi-Garcia, Isabelle, Serrano-Sanchez, Martin, Mitter, Richard, Ivanovic, Zoran, de Verneuil, Hubert, Gribben, John, Taussig, David, Rezvani, Hamid Reza, Mazurier, Frédéric and Bonnet, Dominique 2013. HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress. Cell Stem Cell 13 (5) , pp. 549-563. 10.1016/j.stem.2013.08.011

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Silver, Daniel J., Tugertimur, Bugra, Deleyrolle, Loic P., Siebzehnrubl, Dorit, Sarkisian, Matthew R., Devers, Kelly G., Yachnis, Antony T., Kupper, Marius D., Neal, Daniel, Nabilsi, Nancy H., Kladde, Michael P., Suslov, Oleg, Brabletz, Simone, Brabletz, Thomas, Reynolds, Brent A. and Steindler, Dennis A. 2013. The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Molecular Medicine 5 (8) , pp. 1196-1212. 10.1002/emmm.201302827

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Steindler, Dennis A. 2013. Isolating and culturing of precursor cells from the adult human brain. Reynolds, Brent A. and Delerolle, Loic P., eds. Neural Progenitor Cells, Vol. 1059. Methods in Molecular Biology, Springer, pp. 79-86. (10.1007/978-1-62703-574-3_7)

Silver, Daniel J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Schildts, Michela J., Yachnis, Anthony T., Smith, George M., Smith, Amy A., Scheffler, Bjorn, Reynolds, Brent A., Silver, Jerry and Steindler, Dennis A. 2013. Chondroitin Sulfate Proteoglycans Potently Inhibit Invasion and Serve as a Central Organizer of the Brain Tumor Microenvironment. Journal of Neuroscience 33 (39) , pp. 15603-15617. 10.1523/JNEUROSCI.3004-12.2013

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Piggott, Luke and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2013. Breast cancer stem cells: obstacles to therapy. Cancer Letters 338 (1) , pp. 57-62. 10.1016/j.canlet.2012.04.023

Trejo, C. L., Green, S., Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Collisson, E. A., Iezza, G., Phillips, W. A. and McMahon, M. 2013. Mutationally activated PIK3CAH1047R cooperates with BRAFV600E to promote lung cancer progression. Cancer Research 73 (21) , pp. 6448-6461. 10.1158/0008-5472.CAN-13-0681

Wakefield, Alison Myfanwy, Soukupová, Jitka, Montagne, Amelie, Ranger, Jill, French, Rhiannon, Muller, William and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2013. Bcl3 selectively promotes metastasis of ErbB2-driven mammary tumors. Cancer Research 73 (2) , pp. 745-755. 10.1158/0008-5472.CAN-12-1321

Young, Madeleine 2013. The effects of aberrant Wnt signalling on the murine intestinal stem cell compartment. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Young, Madeleine, Ordonez, Liliana and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. What are the best routes to effectively model human colorectal cancer? Molecular Oncology 7 (2) , pp. 178-189. 10.1016/j.molonc.2013.02.006

Zvelebil, Marketa, Oliemuller, Erik, Gao, Qiong, Wansbury, Olivia, Mackay, Alan, Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Reis-Filho, Jorge S. and Howard, Beatrice A. 2013. Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers. Breast Cancer Research 15 (2) , R25. 10.1186/bcr3403
file

2012

Boyd, Ashleigh S., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Lui, Kathy O., Fu, Xuemei and Xu, Yang 2012. Concise review: Immune recognition of induced pluripotent stem cells. Stem Cells 30 (5) , pp. 797-803. 10.1002/stem.1066

Braun, Sebastian, Humphreys, Christine and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2012. Evolutionary routes from a prebiotic ANA-world. Communicative & Integrative Biology 5 (2) , pp. 199-202. 10.4161/cib.18892

Colmont, Chantal Sophie, Harding, Keith Gordon, Piguet, Vincent and Patel, Girish Khandubhai 2012. Human skin cancer stem cells: a tale of mice and men. Experimental Dermatology 21 (8) , pp. 576-580. 10.1111/j.1600-0625.2012.01533.x

Feng, Gui Jie, Cotta, Welwyn, Wei, Xiao-Qing ORCID: https://orcid.org/0000-0002-6274-8503, Poetz, Oliver, Evans, Rebecca Jane, Jardé, Thierry, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2012. Conditional disruption of Axin1 leads to development of liver tumors in mice. Gastroenterology 143 (6) , pp. 1650-1659. 10.1053/j.gastro.2012.08.047

Gui, Liming and Homer, Hayden 2012. Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes. Development 139 (11) , pp. 1941-1946. 10.1242/dev.078352

Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2012. Impact of interactions between normal and transformed epithelial cells and the relevance to cancer. Cellular and Molecular Life Sciences 69 (2) , pp. 203-213. 10.1007/s00018-011-0806-3

Hopkins, S., Linderoth, E., Hantschel, O., Suarez-Henriques, P., Pilia, G., Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Superti-Furga, G. and Ferby, I. 2012. Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis. Developmental Cell 23 (3) , pp. 547-559. 10.1016/j.devcel.2012.08.001

Jarde, Thierry and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2012. Wnt signalling in murine postnatal mammary gland development. Acta Physiologica 204 (1) , pp. 118-127. 10.1111/j.1748-1716.2011.02283.x

Kallinikou, Konstantina, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Blundell, Michael P., Ings, Stuart J., Watts, Michael J., Thrasher, Adrian J., Linch, David C., Bonnet, Dominique and Yong, Kwee L. 2012. Engraftment defect of cytokine-cultured adult human mobilized CD34+ cells is related to reduced adhesion to bone marrow niche elements. British Journal of Haematology 158 (6) , pp. 778-787. 10.1111/j.1365-2141.2012.09219.x

Khritankova, I. V., Kukharskiy, M. S., Lytkina, O. A., Bachurin, S. O. and Shorning, Boris 2012. Dimebon activates autophagosome components in human neuroblastoma SH-SY5Y cells. Doklady Biochemistry and Biophysics 446 (1) , pp. 251-253. 10.1134/S1607672912050079

Milani, E. S., Brinkhaus, H., Dueggeli, R., Klebba, I., Mueller, U., Stadler, M., Kohler, H., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Bentires-Alj, M. 2012. Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation. Development 140 (1) , pp. 117-125. 10.1242/dev.082941

Muñoz-Descalzo, Silvia, De Navascues Melero, Joaquin ORCID: https://orcid.org/0000-0002-5414-4056 and Arias, Alfonso Martinez 2012. Wnt-Notch signalling: An integrated mechanism regulating transitions between cell states. Bioessays 34 (2) , pp. 110-118. 10.1002/bies.201100102

Ordonez, Liliana and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2012. Who do they think they are? Wnt-responsive cells reveal their family trees. Breast Cancer Research 14 (6) , 327. 10.1186/bcr3351
file

Patel, Girish Khandubhai, Yee, Carole L., Terunuma, Atsushi, Telford, William G., Voong, Nga, Yuspa, Stuart H. and Vogel, Jonathan C. 2012. Identification and characterization of tumor-initiating cells in human primary cutaneous squamous cell carcinoma. Journal of Investigative Dermatology 132 (2) , pp. 401-409. 10.1038/jid.2011.317

Patel, Girish Khandubhai, Yee, Carole L., Yuspa, Stuart H. and Vogel, Jonathan C. 2012. A humanized stromal bed is required for engraftment of isolated human primary squamous cell carcinoma cells in immunocompromised mice. Journal of Investigative Dermatology 132 (2) , pp. 284-290. 10.1038/jid.2011.284

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Tunster, Simon James ORCID: https://orcid.org/0000-0002-2242-9452, Young, Madeleine, Carrico, Adam Stephen, John, Rosalind Margaret ORCID: https://orcid.org/0000-0002-3827-7617 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice. Gut 61 (10) , pp. 1435-1438. 10.1136/gutjnl-2011-300842

Regan, J. L., Kendrick, Howard, Magnay, F.-A., Vafaizadeh, V., Groner, B. and Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 2012. c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer. Oncogene 31 (7) , pp. 869-883. 10.1038/onc.2011.289

Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Tipping, Alex J., Wang, Zhengke and Enver, Tariq 2012. GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia. The International Journal of Biochemistry & Cell Biology 44 (3) , pp. 457-460. 10.1016/j.biocel.2011.12.004

Shorning, Boris, Jarde, Thierry, McCarthy, Afshan, Ashworth, Alan, de Leng, Wendy W. J., Offerhaus, George Johan A., Resta, Nicoletta, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1. Gut 61 (2) , pp. 202-213. 10.1136/gutjnl-2011-300046

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Kendrick, Howard, Sheridan, Julie M., Regan, Joseph L., Prater, Michael D., Lindeman, Geoffrey J., Watson, Christine J., Visvader, Jane E. and Stingl, John 2012. Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods. Journal of Mammary Gland Biology and Neoplasia 17 (2) , pp. 91-97. 10.1007/s10911-012-9257-1

Smartt, Helena J. M., Greenhough, Alexander, Ordonez-Moran, Paloma, Talero, Elena, Cherry, Catherine A., Wallam, Catherine A., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Al Kharusi, Manal Al, Roberts, Heather R., Mariadason, John M., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Huelsken, Joerg, Williams, Ann C. and Paraskeva, Chris 2012. β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells. Gut 61 (9) , pp. 1306-1314. 10.1136/gutjnl-2011-300817

Soady, Kelly and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2012. Slugging their way to immortality: Driving mammary epithelial cells into a stem cell-like state. Breast Cancer Research 14 (5) , 319. 10.1186/bcr3188
file

Soukupova, J., Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2012. Inhibitors of Bcl-3 as a novel therapeutic strategy for HER2+ breast cancer. European Journal of Cancer 48 (5) , S225-S225.

Wang, Shanshan, Okun, Michael S., Suslov, Oleg, Zheng, Tong, McFarland, Nikolaus R., Vedam-Mai, Vinata, Foote, Kelly D., Roper, Steven N., Yachnis, Anthony T., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Steindlera, Dennis A. 2012. Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains. Brain Research 1464 , pp. 61-72. 10.1016/j.brainres.2012.04.039

Williams, Rebecca ORCID: https://orcid.org/0000-0003-2168-7369, Shorning, Boris, Datta, S., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Development and characterisation of a bladder cancer model [Poster]. BJU International 109 (S7) , p. 25. 10.1111/j.1464-410X.2012.11177.x

2011

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2011. Prospective identification and isolation of murine bone marrow derived multipotent mesenchymal progenitor cells. Best Practice & Research Clinical Haematology 24 (1) , pp. 13-24. 10.1016/j.beha.2010.11.003

Annakesavan, Anita, Patel, Girish Khandubhai and Harding, Keith Gordon 2011. Recurrence of diffuse large B cell lymphoma presenting as a chronic non healing wound - case report [Abstract]. Wound Repair and Regeneration 19 (2) , A10. 10.1111/j.1524-475X.2010.00670.x

Bosanquet, David C., Davies, Wendy L., May, Kenneth, Harding, Keith Gordon and Patel, Girish Khandubhai 2011. Acute generalised exanthematous pustulosis following intravitreal Ranibizumab. International Wound Journal 8 (3) , pp. 317-319. 10.1111/j.1742-481X.2011.00799.x

Braun, Sebastian, Humphreys, Christine, Fraser, Elizabeth, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Bochtler, Matthias ORCID: https://orcid.org/0000-0001-7884-4463 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2011. Amyloid-Associated Nucleic Acid Hybridisation. PLoS ONE 6 (5) , e19125. 10.1371/journal.pone.0019125
file

Davies, Emma Jane, Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. Origin and maintenance of the intestinal cancer stem cell. Molecular Carcinogenesis 50 (4) , pp. 254-263. 10.1002/mc.20631

Deleyrolle, Loic P., Harding, Angus, Cato, Kathleen, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Rahman, Maryam, Azari, Hassan, Olson, Sarah, Gabrielli, Brian, Osborne, Geoffrey, Vescovi, Angelo and Reynolds, Brent A. 2011. Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain 134 , pp. 1331-1343. 10.1093/brain/awr081

Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Kajita, Mihoko, Lawrenson, Kate and Fujita, Yasuyuki 2011. Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis. The International Journal of Biochemistry & Cell Biology 43 (4) , pp. 496-503. 10.1016/j.biocel.2010.12.019

Kant, P., Sainsbury, A., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Pollard, S. G., Scott, N., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Coletta, P. L. and Hull, M. A. 2011. Rectal epithelial cell mitosis and expression of macrophage migration inhibitory factor are increased 3 years after Roux-en-Y gastric bypass (RYGB) for morbid obesity: implications for long-term neoplastic risk following RYGB. Gut 60 (7) , pp. 893-901. 10.1136/gut.2010.230755

Knight, James Christopher, Hallett, Andrew Jon, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Paisey, Stephen James ORCID: https://orcid.org/0000-0002-2274-3708, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Edwards, Peter Gerald ORCID: https://orcid.org/0000-0001-6999-753X 2011. Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor. ChemBioChem 12 (17) , pp. 2692-2698. 10.1002/cbic.201100441

Kreuzaler, Peter A., Staniszewska, Anna D., Li, Wenjing, Omidvar, Nader, Kedjouar, Blandine, Turkson, James, Poli, Valeria, Flavell, Richard A., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J. 2011. Stat3 controls lysosomal-mediated cell death in vivo. Nature Cell Biology 13 (3) , pp. 303-309. 10.1038/ncb2171

Matthews, James, Sansom, O. J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. Absolute requirement for STAT3 function in small-intestine crypt stem cell survival. Cell Death and Differentiation 18 (12) , pp. 1934-1943. 10.1038/cdd.2011.77

Miyamoto, T., Porazinski, Sean, Wang, H., Borovina, A., Ciruna, B., Shimizu, A., Kajii, T., Kikuchi, A., Furutani-Seiki, M. and Matsuura, S. 2011. Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates. Human Molecular Genetics 20 (10) , pp. 2058-2070. 10.1093/hmg/ddr090

Molyneux, Gemma and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2011. The cell of origin of BRCA1 mutation-associated breast cancer: a cautionary tale of gene expression profiling. Journal of Mammary Gland Biology and Neoplasia 16 (1) , pp. 51-55. 10.1007/s10911-011-9202-8

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. The roles of the methyl-CpG binding proteins in cancer. Genes & Cancer 2 (6) , pp. 618-630. 10.1177/1947601911418499

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Perez-Mancera, Pedro A., Dow, Lukas E., Ryan, Andrew, Tennstedt, Pierre, Bogani, Debora, Elsum, Imogen, Greenfield, Andy, Tuveson, David A., Simon, Ronald and Humbert, Patrick O. 2011. SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia. The Journal of Clinical Investigation 121 (11) , pp. 4257-4267. 10.1172/JCI58509
file

Perrins, Richard D., Orchard, Craig B., Zavodszky, Maria, Kasry, Amal, Nikolaev, Nikolay, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2011. Doing more with less: a method for low total mass, affinity measurement using variable-length nanotethers. Analytical Chemistry 83 (23) , pp. 8900-8905. 10.1021/ac2012569

Piggott, Luke, Omidvar, Nader, Marti-Perez, Salvador, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2011. Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 13 (5) , R88. 10.1186/bcr2945
file

Porazinski, Sean, Wang, Huijia and Furutani-Seiki, Makoto 2011. Essential techniques for introducing medaka to a zebrafish laboratory-towards the combined use of medaka and zebrafish for further genetic dissection of the function of the vertebrate genome. Pelegri, Francisco J., ed. Vertebrate Embryogenesis, Vol. 770. Methods in Molecular Biology, Springer, pp. 211-241. (10.1007/978-1-61779-210-6_8)

Richards, Alastair J., Hagelstein, Susan M., Patel, Girish Khandubhai, Ivins, Nicola M., Sweetland, Helen Margaret and Harding, Keith Gordon 2011. Early use of negative pressure therapy in combination with silver dressings in a difficult breast abscess. International Wound Journal 8 (6) , pp. 608-611. 10.1111/j.1742-481X.2011.00838.x

Sakthianandeswaren, A., Christie, M., D'Andreti, C., Tsui, C., Jorissen, R. N., Li, S., Fleming, N. I., Gibbs, P., Lipton, L., Malaterre, J., Ramsay, R. G., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Ernst, M., Jeffery, R. E., Poulsom, R., Leedham, S. J., Segditsas, S., Tomlinson, I. P. M., Bernhard, O. K., Simpson, R. J., Walker, F., Faux, M. C., Church, N., Catimel, B., Flanagan, D. J., Vincan, E. and Sieber, O. M. 2011. PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis. Cancer Research 71 (10) , pp. 3709-3719. 10.1158/0008-5472.CAN-10-2342

Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Jiang, David G., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Harding, Keith Gordon and Patel, Girish Khandubhai 2011. Activated leukocyte cell adhesion molecule impacts on clinical wound healing and inhibits HaCaT migration. International Wound Journal 8 (5) , pp. 500-507. 10.1111/j.1742-481X.2011.00823.x

Shorning, Boris and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. LKB1 loss of function studied in vivo. FEBS Letters 585 (7) , pp. 958-966. 10.1016/j.febslet.2011.01.019

Shorning, Boris, Griffiths, David Francis Rees and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder. PLoS ONE 6 (1) , e16209. 10.1371/journal.pone.0016209
file

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Reynolds, B. A., Vescovi, A., Steindler, D. A. and Deleyrolle, L. P. 2011. The origins of glioma: E pluribus unum? GLIA 59 (8) , pp. 1135-1147. 10.1002/glia.21143

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Vedam-Mai, Vinata, Azari, Hassan, Reynolds, Brent A. and Deleyrolle, Loic P. 2011. Isolation and characterization of adult neural stem cells. Filippi, Marie-Dominique and Geiger, Hartmut, eds. Stem Cell Migration, Vol. 750. Methods in Molecular Biology, Springer, pp. 61-77. (10.1007/978-1-61779-145-1_4)

Steffenhagen, Carolin, Kraus, Sabrina, Dechant, Franz-Xaver, Kandasamy, Mahesh, Lehner, Bernadette, Poehler, Anne-Maria, Furtner, Tanja, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Couillard-Despres, Sebastien, Strauss, Olaf, Aigner, Ludwig and Rivera, Francisco J. 2011. Identity, fate and potential of cells grown as neurospheres: species matters. Stem Cell Reviews and Reports 7 (4) , pp. 815-835. 10.1007/s12015-011-9251-9

Thomas, Rhian Sara, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2011. Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis. Arthritis Research and Therapy 13 (6) , R203. 10.1186/ar3536
file

Vargaftig, J., Taussig, D. C., Griessinger, E., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Lister, T. A., Cavenagh, J., Oakervee, H., Gribben, J. and Bonnet, Dominique 2011. Frequency of leukemic initiating cells does not depend on the xenotransplantation model used. Leukemia 26 (4) , pp. 858-860. 10.1038/leu.2011.250

Wansbury, Olivia, Mackay, Alan, Kogata, Naoko, Mitsopoulos, Costas, Kendrick, Howard, Davidson, Kathryn, Ruhrberg, Christiana, Reis- Filho, Jorge, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Zvelebil, Marketa and Howard, Beatrice 2011. Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment. Breast Cancer Research 13 (4) , R79. 10.1186/bcr2928
file

Young, Madeleine and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. Expanding the p53 toolkit: A new platform for rapid engineering of the p53 locus in vivo [Note]. Cell Cycle 10 (14) , p. 2249. 10.4161/cc.10.14.16205

2010

Ashton, Gabrielle H., Morton, Jennifer P., Myant, Kevin, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Ridgway, Rachel A., Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Wilkins, Julie A., Athineos, Dimitris, Muncan, Vanesa, Kemp, Richard, Neufeld, Kristi, Clevers, Hans, Brunton, Valerie, Winton, Douglas J., Wang, Xiaoyan, Sears, Rosalie C., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Frame, Margaret C. and Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 2010. Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling. Developmental Cell 19 (2) , pp. 259-269. 10.1016/j.devcel.2010.07.015

Buchert, Michael, Athineos, Dimitris, Abud, Helen E., Burke, Zoe D., Faux, Maree C., Samuel, Michael S., Jarnicki, Andrew G., Winbanks, Catherine E., Newton, Ian P, Meniel, Valerie, Suzuki, Hiromu, Stacker, Steven A., Näthke, Inke S., Tosh, David, Huelsken, Joerg, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Heath, Joan K., Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Ernst, Matthias 2010. Genetic dissection of differential signaling threshold requirements for the Wnt/beta-Catenin pathway in vivo. PLOS Genetics 6 (1) , e1000816. 10.1371/journal.pgen.1000816
file

Cole, Alicia M., Myant, Kevin, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Ridgway, Rachel A., Athineos, Dimitris, Van den Brink, Gijs, Muncan, Vanesa, Clevers, Hans, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Sicinski, Peter and Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 2010. Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss. Cancer Research 70 (20) , pp. 8149-8158. 10.1158/0008-5472.CAN-10-0315

Cole, Alicia, Ridgway, Rachel, Derkits, Sahra, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Barker, Nick, Clevers, Hans, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen 2010. p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium. EMBO Molecular Medicine 2 (11) , pp. 472-486. 10.1002/emmm.201000101

Coras, Roland, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Pauli, Elisabeth, Huttner, Hagen B., Njunting, Marleisje, Kobow, Katja, Villmann, Carmen, Hahnen, Eric, Neuhuber, Winfried, Weigel, Daniel, Buchfelder, Michael, Stefan, Hermann, Beck, Heinz, Steindler, Dennis A. and Bluemcke, Ingmar 2010. Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain 133 (11) , pp. 3359-3372. 10.1093/brain/awq215

De Navascues Melero, Joaquin ORCID: https://orcid.org/0000-0002-5414-4056 and Modolell, Juan 2010. The pronotum LIM-HD gene tailup is both a positive and a negative regulator of the proneural genes achaete and scute of Drosophila. Mechanisms of Development 127 (9-12) , pp. 393-406. 10.1016/j.mod.2010.05.001

Evers, Bastiaan, Speksnijder, Ewoud N., Schut, Eva, Ciampricotti, Metamia, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Derksen, Patrick W. B., Jonkers, Jos and de Visser, Karin E. 2010. A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis. Journal of Pathology 220 (1) , pp. 34-44. 10.1002/path.2655

Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009, Pajak, Bozena, Stubbs, M., Todd, H., Barbeau, O., Quevedo, C., Botfield, H., Young, R., Ruddle, R., Samuel, L., Battersby, Alysia Agnes, Raynaud, F., Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X, Wilson, Samuel, Latinkic, Branko ORCID: https://orcid.org/0000-0003-4952-123X, Workman, P., McDonald, E., Blagg, J., Aherne, W. and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2010. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Research 70 (14) , pp. 5963-5973. 10.1158/0008-5472.CAN-10-1028

Ghafoor, Sana Z. A., MacRae, Eva A., Harding, Keith Gordon and Patel, Girish Khandubhai 2010. Symmetrical peripheral digital gangrene following severe Plasmodium falciparum malaria-induced disseminated intravascular coagulopathy. International Wound Journal 7 (5) , pp. 418-422. 10.1111/j.1742-481X.2010.00697.x

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Patel, Girish Khandubhai and Harding, Keith Gordon 2010. Expression of WAVEs, the WASP (Wiskott-Aldrich syndrome protein) family of verprolin homologous proteins in human wound tissues and the biological influence on human keratinocytes. Wound Repair and Regeneration 18 (6) , pp. 594-604. 10.1111/j.1524-475X.2010.00630.x

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Patel, Girish Khandubhai and Harding, Keith Gordon 2010. Expression of WAVEs, the WASP (Wiskott-Aldrich syndrome protein) family of verprolin homologous proteins, in human wound tissues and the cellular impact of WAVEs on keratinocytes [Abstract]. Wound Repair and Regeneration 18 (6) , A84. 10.1111/j.1524-475X.2010.00633.x

Kajita, Mihoko, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Harris, Andrew R., Dupre-Crochet, Sophie, Itasaki, Nobue, Kawakami, Koichi, Charras, Guillaume, Tada, Masazumi and Fujita, Yasuyuki 2010. Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells. Journal of Cell Science 123 (2) , pp. 171-180. 10.1242/jcs.057976

Minhas, Uzma, Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Patel, Girish Khandubhai, Harding, Keith Gordon and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. Activated leukocyte cell adhesion molecule (ALCAM) - biological impact on vascular endothelial cells [Abstract]. Wound Repair and Regeneration 18 (6) , A89. 10.1111/j.1524-475X.2010.00633.x

Molyneux, Gemma, Geyer, Felipe, Magnay, Fiona-Ann, McCarthy, Afshan, Kendrick, Howard, Natrajan, Rachael, MacKay, Alan, Grigoriadis, Anita, Tutt, Andrew, Ashworth, Alan, Reis-Filho, Jorge and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2010. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 7 (3) , pp. 403-417. 10.1016/j.stem.2010.07.010

Patel, Girish Khandubhai and Harding, Keith Gordon 2010. Nicorandil ulcer: moves beyond the mucosa. Annals of the Royal College of Surgeons of England 92 (6) , pp. 451-452. 10.1308/003588410X12699663905195

Patel, Girish Khandubhai, Davies, Wendy L., Price, Patricia Elaine and Harding, Keith Gordon 2010. Ulcerated tophaceous gout. International Wound Journal 7 (5) , pp. 423-427. 10.1111/j.1742-481X.2010.00700.x

Porazinski, Sean, Wang, Huijia and Furutani-Seiki, Makoto 2010. Microinjection of medaka embryos for use as a model genetic organism. Journal of Visualized Experiments (46) , e1937. 10.3791/1937

Poulin, L. F., Salio, M., Griessinger, E., Anjos-Afonso, F. ORCID: https://orcid.org/0000-0003-4392-488X, Craciun, L., Chen, J. -L., Keller, A. M., Joffre, O., Zelenay, S., Nye, E., Le Moine, A., Faure, F., Donckier, V., Sancho, D., Cerundolo, V., Bonnet, D. and Reis e Sousa, C. 2010. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8 + dendritic cells. Journal of Experimental Medicine 207 (6) , pp. 1261-1271. 10.1084/jem.20092618

Rangaraj, Aravindan, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Patel, Girish Khandubhai, Harding, Keith Gordon and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. The role of Bik1 (BCL-2 interaction killer) in wound healing [Abstract]. Wound Repair and Regeneration 18 (6) , A92. 10.1111/j.1524-475X.2010.00633.x

Rangaraj, Aravindan, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Patel, Girish Khandubhai, Price, Patricia Elaine, Harding, Keith Gordon and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. The molecular and cellular roles of Psoriasin (S100A4) in human cutaneous wound healing [Abstract]. Wound Repair and Regeneration 18 (6) , A92. 10.1111/j.1524-475X.2010.00633.x

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2010. Isolation, culture and analysis of mouse mammary epithelial cells. Ward, Andrew and Tosh, David, eds. Mouse cell culture : methods and protocols, Methods in Molecular Biology, vol. 633. New York: Springer-Verlag, pp. 139-170. (10.1007/978-1-59745-019-5_11)

van Dop, Willemijn, Heijmans, Jarom, Büller, Nikè, Snoek, Susanne, Rosekrans, Sanne, Wassenberg, Elisabeth, van den Bergh Weerman, Marius, Lanske, Beate, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Winton, Douglas, Wijgerde, Mark, Offerhaus, G. Johan, Hommes, Daan, Hardwick, James, de Jonge, Wouter, Biemond, Izak and van den Brink, Gijs 2010. Loss of Indian hedgehog activates multiple aspects of a wound healing response in the mouse intestine. Gastroenterology 139 (5) , pp. 1665-1676. 10.1053/j.gastro.2010.07.045

Wolkenhauer, Olaf, Auffray, Charles, Baltrusch, Simone, Blüthgen, Nils, Byrne, Helen, Cascante, Marta, Ciliberto, Andrea, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Drasdo, Dirk, Fell, David, Ferrell, James Jr. E., Gallahan, Daniel, Gatenby, Robert, Günther, Ulrich, Harms, Brian D., Herzel, Hanspeter, Junghanss, Christian, Kunz, Manfred, van Leeuwen, Ingeborg, Lenormand, Philippe, Levi, Francis, Linnebacher, Michael, Lowengrub, John, Maini, Philip K., Malik, Arif, Rateitschak, Katja, Sansom, Owen, Schäfer, Reinhold, Schürrle, Karsten, Sers, Christine, Schnell, Santiago, Shibata, Darryl, Tyson, John, Vera, Julio, White, Michael, Zhivotovsky, Boris and Jaster, Robert 2010. Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Research 70 (1) , pp. 12-13. 10.1158/0008-5472.CAN-09-2676

2009

Alexander, Caroline M., Puchalski, Joel, Klos, Kristine S., Badders, Nisha, Ailles, Laurie, Kim, Carla F., Dirks, Peter and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2009. Separating stem cells by flow cytometry: reducing variability for solid tissues. Cell Stem Cell 5 (6) , pp. 579-583. 10.1016/j.stem.2009.11.008

Barker, Nick, Ridgway, Rachel A., Van Es, Johan H., Van De Wetering, Marc, Begthel, Harry, Van Den Born, Maaike, Danenberg, Esther, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Sansom, Owen J. and Clevers, Hans 2009. Crypt stem cells as the cells-of-origin of intestinal cancer [Letter]. Nature 457 (7229) , pp. 608-611. 10.1038/nature07602

Bentires-Alj, Mohamed, Clarke, Robert B., Jonkers, Jos, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Stein, Torsten 2009. It's all in the details: methods in breast development and cancer [Meeting Report]. Breast Cancer Research 11 (4) , 305. 10.1186/bcr2346
file

Bollrath, Julia, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, von Burstin, Vivian A., Putoczki, Tracy, Bennecke, Moritz, Bateman, Trudie, Nebelsiek, Tim, Lundgren-May, Therese, Canli, Özge, Schwitalla, Sarah, Matthews, Vance, Schmid, Roland M., Kirchner, Thomas, Arkan, Melek C., Ernst, Matthias and Greten, Florian R. 2009. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15 (2) , pp. 91-102. 10.1016/j.ccr.2009.01.002
file

Britt, Kara L., Kendrick, Howard, Regan, Joseph L., Molyneux, Gemma, Magnay, Fiona-Ann, Ashworth, Alan and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2009. Pregnancy in the mature adult mouse does not alter the proportion of mammary epithelial stem/progenitor cells. Breast Cancer Research 11 (2) , R20. 10.1186/bcr2245

Burke, Zoé D., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Tosh, David 2009. Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism. Gastroenterology 136 (7) , pp. 2316-2324. 10.1053/j.gastro.2009.02.063

Greenow, Kirsty Rhian, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496 2009. Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation. Oncogene 28 (11) , pp. 1443-1453. 10.1038/onc.2008.482

Grigoriadis, Anita, Oliver, Gavin, Tanney, Austin, Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Jat, Parmjit and Neville, A. Munro 2009. Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues. BMC Genomics 10 (1) , 324. 10.1186/1471-2164-10-324
file

Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Dupré-Crochet, Sophie, Norman, Mark, Kajita, Mihoko, Zimmermann, Carola, Pelling, Andrew E., Piddini, Eugenia, Baena-López, Luis Alberto, Vincent, Jean-Paul, Itoh, Yoshifumi, Hosoya, Hiroshi, Pichaud, Franck and Fujita, Yasuyuki 2009. Characterization of the interface between normal and transformed epithelial cells [Letter]. Nature Cell Biology 11 (4) , pp. 460-467. 10.1038/ncb1853

Homer, Hayden, Gui, Liming and Carroll, John 2009. A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression. Science 326 (5955) , pp. 991-994. 10.1126/science.1175326

Huser, C. A., Pringle, M. A., Heath, V. J., Bell, A. K., Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Crighton, D., Ryan, K. M., Gusterson, B. A. and Stein, T. 2009. TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival. Cell Death and Differentiation 17 (2) , pp. 304-315. 10.1038/cdd.2009.126

Jasani, Bharat, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Hutcheson, Iain Robert, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Bartlett, J. and Barrett-Lee, Peter 2009. Resistance to HER2-directed trastuzumab therapy in breast cancer. Advances in Breast Cancer 6 (3) , pp. 11-18.

Kasry, Amal, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314, Davies, Philip Rosser ORCID: https://orcid.org/0000-0003-4394-766X, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169, Thomas, Nick, Lofas, Stefan and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2009. Comparison of methods for generating planar DNA-modified surfaces for hybridization studies. ACS Applied Materials & Interfaces 1 (8) , pp. 1793-1798. 10.1021/am9003073

Kranc, Kamil R., Schepers, Hein, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Bamforth, Simon, Villadsen, Ellen, Ferry, Helen, Bouriez-Jones, Tiphaine, Sigvardsson, Mikael, Bhattacharya, Shoumo, Jacobsen, Sten Eirik and Enver, Tariq 2009. Cited2 is an essential regulator of adult hematopoietic stem cells. Cell Stem Cell 5 (6) , pp. 659-665. 10.1016/j.stem.2009.11.001

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2009. K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse. Cancer Research 69 (1) , pp. 94-101. 10.1158/0008-5472.CAN-08-2895

Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2009. Normal stem cells in cancer prone epithelial tissues. British Journal of Cancer 100 (2) , pp. 221-227. 10.1038/sj.bjc.6604850

Rivera, Francisco J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kandasamy, Mahesh, Couillard-Despres, Sebastien, Caioni, Massimiliano, Poehler, Anne-Maria, Berninger, Benedikt, Sandner, Beatrice, Bogdahn, Ulrich, Goetz, Magdalena, Bluemcke, Ingmar, Weidner, Norbert and Aigner, Ludwig 2009. Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures. Cellular Physiology and Biochemistry 24 (3-4) , pp. 317-324. 10.1159/000233256

Ruzov, Alexey, Shorning, Boris, Mortusewicz, Oliver, Dunican, Donncha S., Leonhardt, Heinrich and Meehan, Richard R. 2009. MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development 136 (13) , pp. 2277-2286. 10.1242/dev.032227

Shorning, Boris, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, McCarthy, Afshan, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Winton, Douglas J., Sansom, Owen J., Ashworth, Alam and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2009. Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine. PLoS ONE 4 (1) , e4264. 10.1371/journal.pone.0004264
file

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Jeske, Ina, Mueller, Dorit, Buslei, Rolf, Coras, Roland, Hahnen, Eric, Huttner, Hagen B., Corbeil, Denis, Kaesbauer, Johanna, Appl, Thomas, von Hoersten, Stephan and Bluemcke, Ingmar 2009. Spontaneous in vitro transformation of adult neural precursors into stem-like cancer cells. Brain Pathology 19 (3) , pp. 399-408. 10.1111/j.1750-3639.2008.00189.x

Smith, Paul James, Furon, Emeline, Wiltshire, Marie, Campbell, Lee, Feeney, Graham P., Snyder, R. D. and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2009. ABCG2-Associated Resistance to Hoechst 33342 and Topotecan in a Murine Cell Model with Constitutive Expression of Side Population Characteristics. Cytometry Part A 75A (11) , pp. 924-933. 10.1002/cyto.a.20800

Tipping, A. J., Pina, C., Castor, A., Hong, D., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Lazzari, L., May, G. E., Jacobsen, S. E. W. and Enver, T. 2009. High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. Blood 113 (12) , pp. 2661-2672. 10.1182/blood-2008-06-161117

Weiss, S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kreutzer, J., Bluemcke, I. and Buslei, R. 2009. Evidence for a progenitor cell population in the human pituitary. Clinical Neuropathology 28 (4) , pp. 309-318.

2008

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2008. Isolation, culture, and differentiation potential of mouse marrow stromal cells. Current Protocols in Stem Cell Biology 10.1002/9780470151808.sc02b03s7

Cariati, Massimiliano, Naderi, Ali, Brown, John P., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Pinder, Sarah E., Caldas, Carlos and Purushotham, Anand D. 2008. Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line. International Journal of Cancer 122 (2) , pp. 298-304. 10.1002/ijc.23103

University College Cardiff Consultants, Ltd. 2008. Method of measuring the affinity of biomolecules. EP1949104A2. [Patent].

Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2008. The potential for targeting oncogenic WNT/beta-catenin signaling in therapy. Current Drug Targets 9 (7) , pp. 532-547. 10.2174/138945008784911787

Freeman, Jamie, Zollo, M. and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2008. Investigating h-Prune activation of Wnt signalling in breast cancer. Breast Cancer Research 10 (s2) , p. 10. 10.1186/bcr1899
file

Huttner, Hagen B., Janich, Peggy, Koehrmann, Martin, Jaszai, Jozsef, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Bluemcke, Ingmar, Suttorp, Meinolf, Gahr, Manfred, Kuhnt, Daniela, Nimsky, Christopher, Krex, Dietmar, Schackert, Gabriele, Loewenbrueck, Kai, Reichmann, Heinz, Juettler, Eric, Hacke, Werner, Schellinger, Peter D., Schwab, Stefan, Wilsch-Braeuninger, Michaela, Marzesco, Anne-Marie and Corbeil, Denis 2008. The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease. Stem Cells 26 (3) , pp. 698-705. 10.1634/stemcells.2007-0639

Kadri, Hachemi, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009 and Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236 2008. The design, synthesis and antitumour evaluation of novel small molecule inhibitors of the Dishevelled PDZ domain [Poster Presentation/Abstract]. EJC Supplements 6 (12) , p. 137. 10.1016/S1359-6349(08)72370-X

Kendrick, Howard, Regan, Joseph, Magnay, Fiona-Ann, Grigoriadis, Anita, Mitsopoulos, Costas, Zvelebil, Marketa and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2008. Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics 9 (1) , 591. 10.1186/1471-2164-9-591
file

Lindeman, Geoffrey, Visvader, Jane, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Eaves, Connie 2008. The future of mammary stem cell biology: the power of in vivo transplants [Letter]. Breast Cancer Research 10 (3) , p. 402. 10.1186/bcr1986
file

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Winton, Douglas J., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Dubois, Nicole, Trumpp, Andreas, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation. Nature Genetics 40 (12) , pp. 1436-1444. 10.1038/ng.256

Melchor, Lorenzo and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2008. Highway to heaven: mammary gland development and differentiation. Breast Cancer Research 10 (5) , pp. 305-307. 10.1186/bcr2147
file

Pálmer, Héctor G., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Carmeliet, Geert, Takeda, Hikaru and Watt, Fiona M. 2008. The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS ONE 3 (1) , e1483. 10.1371/journal.pone.0001483
file

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2008. Development and characterisation of novel mouse models of human prostate cancer. PhD Thesis, Cardiff University.
file

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, McCarthy, A., Collins, C. M., Ashworth, A. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. Lkb1 defiency causes prostate neoplasia in the mouse. Cancer Research 68 (7) , pp. 2223-2232. 10.1158/0008-5472.CAN-07-5169

Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. Deficiency of Mbd2 attenuates Wnt induced tumourigenesis via deregulation of a novel Wnt inhibitor, Lect.2. Molecular and Cellular Biology 28 (19) , pp. 6094-6103. 10.1128/MCB.00539-08

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Athineos, Dimitris, Meniel, Valerie, Wilkins, Julie Ann, Ridgeway, Rachel A., Burke, Zoe D., Muncan, Vanesa, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 2008. B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 105 (48) , pp. 18919-18923. 10.1073/pnas.0805778105

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie, Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Cole, Alicia, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine. BMC Cancer 8 , 162. 10.1186/1471-2407-8-162
file

Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Boyd, Ashleigh S., Fugazza, Cristina, May, Gillian E., Guo, YanPing, Tipping, Alex J., Scadden, David T., Vyas, Paresh and Enver, Tariq 2008. GATA-2 regulates granulocyte-macrophage progenitor cell function. Blood 112 (13) , pp. 4862-4873. 10.1182/blood-2008-01-136564

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Blumcke, Ingmar 2008. Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies. Epilepsia 49 (s5) , pp. 55-65. 10.1111/j.1528-1167.2008.01638.x

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Reis-Filho, Jorge and Ashworth, Alan 2008. BRCA1 and stem cells: tumour typecasting. Nature Cell Biology 10 (4) , pp. 377-379. 10.1038/ncb0408-377

Taussig, D. C., Miraki-Moud, F., Anjos-Afonso, F. ORCID: https://orcid.org/0000-0003-4392-488X, Pearce, D. J., Allen, K., Ridler, C., Lillington, D., Oakervee, H., Cavenagh, J., Agrawal, S. G., Lister, T. A., Gribben, J. G. and Bonnet, D. 2008. Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells. Blood -New York- 112 (3) , pp. 568-575. 10.1182/blood-2007-10-118331

Tiffen, P., Omidvar, Nader, Marquez, Nuria, Croston, D., Watson, C. and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2008. A dual role for Oncostatin M signalling in the differentiation and death of mammary epithelial cells in vivo. Molecular Endocrinology 22 (12) , pp. 2677-2688. 10.1210/me.2008-0097

Wakefield, A., Piggott, Luke, Croston, D., Jiang, W. G. and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2008. Suppression of the NF-kappa B cofactor Bcl3 inhibits mammary epithelial cell apoptosis and, in breast tumours, correlates with poor prognosis. Breast Cancer Research 10 (S2) , O4. 10.1186/bcr1884
file

2007

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2007. Flexible and dynamic organization of bone marrow stromal compartment. British Journal of Haematology 139 (3) , pp. 373-384. 10.1111/j.1365-2141.2007.06827.x

Britt, K., Ashworth, A. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Pregnancy and the risk of breast cancer. Endocrine-Related Cancer 14 (4) , pp. 907-933. 10.1677/ERC-07-0137

Buslei, Rolf, Hoelsken, Annett, Hofmann, Bernd, Kreutzer, Juergen, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Hans, Volkmar, Oppel, Falk, Buchfelder, Michael, Fahlbusch, Rudolf and Bluemcke, Ingmar 2007. Nuclear beta-catenin accumulation associates with epithelial morphogenesis in craniopharyngiomas. Acta Neuropathologica 113 (5) , pp. 585-590.

Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Meniel, Valerie 2007. The intestinal stem cell niche studied through conditional transgenesis. Presented at: The Cancer Stem Cell Workshop, Berlin, Germany, November 15- 17 2006. Published in: Wiestler, O. D., Haendler, B. and Mumberg, D. eds. Cancer Stem Cells: Novel Concepts and Prospects for Tumor Therapy. Cancer Stem Cells: Novel Concepts and Prospects for Tumor Therapy. Ernst Schering Foundation Symposium Proceedings , vol.2006/5 Berlin: Springer, pp. 99-108. 10.1007/2789_2007_046

Coras, Roland, Hoelsken, Annett, Seufert, Sebastian, Hauke, Jan, Eyuepoglu, Ilker Y., Reichel, Martin, Traenkle, Christian, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, Rolf, Bluemcke, Ingmar and Hahnen, Eric 2007. The peroxisome proliferator-activated receptor-gamma agonist troglitazone inhibits transforming growth factor-beta-mediated glioma cell migration and brain invasion. Molecular Cancer Therapeutics 6 (6) , pp. 1745-1754. 10.1158/1535-7163.MCT-06-0763

De Navascues Melero, Joaquin ORCID: https://orcid.org/0000-0002-5414-4056 and Modolell, J. 2007. tailup, a LIM-HD gene, and Iro-C cooperate in Drosophila dorsal mesothorax specification. Development 134 (9) , pp. 1779-1788. 10.1242/dev.02844

Dikovskaya, Dina, Schiffmann, David, Newton, Ian P., Oakley, Abigail, Kroboth, Karin, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Jamieson, Thomas J., Meniel, Valerie, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Nathke, Inke S. 2007. Correction 176, p. 183. Journal of cell biology 176 (3) , p. 369. 10.1083/jcb.20061009920070116c

Dikovskaya, Dina, Schiffmann, David, Newton, Ian P., Oakley, Abigail, Kroboth, Karin, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Jamieson, Thomas J., Meniel, Valerie, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Nathke, Inke S. 2007. Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. Journal of cell biology 176 (2) , pp. 183-195. 10.1083/jcb.200610099

Dupre-Crochet, S., Figueroa, A., Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Ferber, E. C., Bialucha, C. U., Adams, J., Richardson, E. C. N. and Fujita, Y. 2007. Casein Kinase 1 Is a novel negative regulator of E-cadherin-based cell-cell contacts. Molecular and Cellular Biology 27 (10) , pp. 3804-3816. 10.1128/MCB.01590-06

Forde, Josephine and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2007. Glycogen synthase kinase 3: A key regulator of cellular fate. Cellular and Molecular Life Sciences 64 (15) , pp. 1930-1944. 10.1007/s00018-007-7045-7

Hosking, C. R., Ulloa, F., Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Ferber, E. C., Figueroa, A., Gevaert, K., Birchmeier, W., Briscoe, J. and Fujita, Y. 2007. The transcriptional repressor Glis2 Is a novel binding partner for p120 catenin. Molecular biology of the cell 18 (5) , pp. 1918-1927. 10.1091/mbc.E06-10-0941

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2007. Intestinal homeostasis and neoplasia studied using conditional transgenesis. Expert Review of Anticancer Therapy 7 (4) , pp. 519-531. 10.1586/14737140.7.4.519

Matthews, James, Watson, Susan M. R., Tevendale, Maxine C. L., Watson, Christine J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2007. Caspase-dependent proteolytic cleavage of STAT3a in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines. BMC Cancer 7 (29) , pp. 1-12. 10.1186/1471-2407-7-29
file

Molyneux, G., Regan, J. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Common molecular mechanisms of mammary gland development and breast cancer. Cellular and Molecular Life Sciences 64 (24) , pp. 3248-3260. 10.1007/s00018-007-7391-5

Nijnik, Anastasia, Woodbine, Lisa, Marchetti, Caterina, Dawson, Sara, Lambe, Teresa, Liu, Cong, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Crockford, Tanya L., Cabuy, Erik, Vindigni, Alessandro, Enver, Tariq, Bell, John I., Slijepcevic, Predrag, Goodnow, Christopher C., Jeggo, Penelope A. and Cornall, Richard J. 2007. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447 (7145) , pp. 686-690. 10.1038/nature05875

Oosterveen, Tony, Coudreuse, Damien Y.M., Yang, Pei-Tzu, Fraser, Elizabeth, Bergsma, Joost, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Korswagen, Hendrik C. 2007. Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans. Developmental Biology 308 (2) , pp. 438-448. 10.1016/j.ydbio.2007.05.043

Pearce, Daniel J., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Ridler, Christopher M., Eddaoudi, Ayad and Bonnet, Dominique 2007. Age-dependent increase in side population distribution within hematopoiesis: Implications for our understanding of the mechanism of aging. Stem Cells 25 (4) , pp. 828-835. 10.1634/stemcells.2006-0405

Pearce, Daniel J., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Ridler, Christopher M., Eddaoudi, Ayad and Bonnet, Dominique 2007. Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging. Stem Cells 25 (7) , p. 1852. 10.1634/stemcells.2006-0405erratum

Regan, Joseph and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland. Stem Cell Reviews 3 (2) , pp. 124-136. 10.1007/s12015-007-0017-3

Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Meniel, Valerie, Muncan, Vanesa, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Wilkins, Julie Ann, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Vass, Keith, Athineos, Dimitris, Clevers, Hans and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2007. Myc deletion rescues Apc deficiency in the small intestine. Nature 446 (7136) , pp. 676-679. 10.1038/nature05674

Shaw, Paul ORCID: https://orcid.org/0000-0002-7467-0619 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2007. Murine models of intestinal cancer: Recent advances. DNA Repair 6 (10) , pp. 1403-1412. 10.1016/j.dnarep.2007.02.022

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, Rolf, Eyupoglu, Ilker Y., Seufert, Sebastian, Hahnen, Eric and Blumcke, Ingmar 2007. Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells. Experimental Brain Research 176 (4) , pp. 672-678. 10.1007/s00221-006-0831-x

Sleeman, K. E., Kendrick, H., Robertson, D., Isacke, C. M., Ashworth, A. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. Journal of cell biology 176 (1) , pp. 19-26. 10.1083/jcb.200604065

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Iravani, M., Leao, M., Grigoriadis, A., Kendrick, Howard, Dexter, T., Fenwick, K., Regan, J. L., Britt, K., McDonald, S., Lord, C. J., Mackay, A. and Ashworth, A. 2007. Regulator of G-protein signalling 2 (RGS2) mRNA is differentially expressed in mammary epithelial subpopulations and overexpressed in the majority of breast cancers. Breast Cancer Research 9 (6) , R85. 10.1186/bcr1834

Sykacek, P., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Print, C., Furlong, R. and Micklem, G. 2007. Bayesian modelling of shared gene function. Bioinformatics 23 (15) , pp. 1936-1944. 10.1093/bioinformatics/btm280

2006

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2006. Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment. Blood 109 (3) , pp. 1298-1306. 10.1182/blood-2006-06-030551

Buslei, R., Kreutzer, J., Hofmann, B., Schmidt, V., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Hahnen, E., Eyupoglu, I. Y., Fahlbusch, R. and Blumcke, I. 2006. Abundant hypermethylation of SOCS-1 in clinically silent pituitary adenomas. Acta Neuropathologica 111 (3) , pp. 264-271. 10.1007/s00401-005-0009-9

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Boland, Marion P., Kritikou, Ekaterini A., Lee, Jennifer M., Freeman, Tom C., Tiffen, Paul G. and Watson, Christine J. 2006. The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Molecular Endocrinology 20 (3) , pp. 675-685. 10.1210/me.2005-0392

Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2006. Kinase cogs go forward and reverse in the Wnt signaling machine. Nature Structural & Molecular Biology 13 (1) , pp. 9-11. 10.1038/nsmb0106-9

Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2006. Protein and nucleic acid together: A mechanism for the emergence of biological selection. Journal of Theoretical Biology 240 (3) , pp. 337-342. 10.1016/j.jtbi.2005.09.027

Eyupoglu, I. Y., Hahnen, E., Tränkle, C., Savaskan, N. E., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, R., Lemke, D., Wick, W., Fahlbusch, R. and Blümcke, I. 2006. Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275. Molecular Cancer Therapeutics 5 (5) , p. 1248. 10.1158/1535-7163.MCT-05-0533

Fujita, Yasuyuki, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 and Braga, Vania M. M. 2006. Regulation of cell–cell adhesion by Rap1. Methods in Enzymology 407 , pp. 359-372. 10.1016/S0076-6879(05)07030-8

Hahnen, E., Eyupoglu, I. Y., Brichta, L., Haastert, K., Trankle, C., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Riessland, M., Holker, I., Claus, P., Romstock, J., Buslei, R., Wirth, B. and Blumcke, I. 2006. In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy. Journal of Neurochemistry 98 (1) , pp. 193-202. 10.1111/j.1471-4159.2006.03868.x

Hay, T., Jenkins, H., Sansom, O. J., Martin, N. M. B., Smith, G. C. M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2006. Brca2 deficiency sensitizes cells to PARP inhibition [Correction to Hay et al. 65 (22): 10145]. Cancer Research 66 (1) , p. 599. 10.1158/0008-5472.CAN-66-1-COR

Hoelsken, Annett, Eyuepoglu, Ilker Y., Lueders, Mike, Traenkle, Christian, Dieckmann, Detlef, Buslei, Rolf, Hahnen, Eric, Bluemcke, Ingmar and Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 2006. Ex vivo therapy of malignant melanomas transplanted into organotypic brain slice cultures using inhibitors of histone deacetylases. Acta Neuropathologica 112 (2) , pp. 205-215. 10.1007/s00401-006-0082-8

Muncan, Vanesa, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Tertoolen, Leon, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Begthel, Harry, Sancho, Elena, Cole, Alicia M., Gregorieff, Alex, de Alboran, Ignacio Moreno, Clevers, Hans and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2006. Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc. Molecular and Cellular Biology 26 (22) , pp. 8418-8426. 10.1128/MCB.00821-06
file

Patel, Girish Khandubhai, Goodwin, Richard, Chawla, Maureen, Laidler, Peter, Price, Patricia Elaine, Finlay, Andrew Yule ORCID: https://orcid.org/0000-0003-2143-1646 and Motley, Richard J. 2006. Imiquimod 5% cream monotherapy for cutaneous squamous cell carcinoma in situ (Bowen's disease): a randomized, double-blind, placebo-controlled trial. Journal of the American Academy of Dermatology 54 (6) , pp. 1025-1032. 10.1016/j.jaad.2006.01.055

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Hayes, Anthony Joseph, Gescher, Andreas J., Peters, Jefferey M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2006. PPARδ status and mismatch repair mediated neoplasia in the mouse intestine. BMC Cancer 6 (113) 10.1186/1471-2407-6-113
file

Robinson, H. M. R., Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Walker, M., Zachos, G., Brown, R., Cassidy, J. and Gillespie, D. A. F. 2006. Chk1-dependent slowing of S-phase progression protects DT40 B-lymphoma cells against killing by the nucleoside analogue 5-fluorouracil. Oncogene 25 (39) , pp. 5359-5369. 10.1038/sj.onc.1209532

Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Meniel, Valerie, Wilkins, Julie Ann, Cole, Alicia M., Oien, Karin A., Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Jamieson, Thomas J., Guerra, Carmen, Ashton, Gabrielle H., Barbacid, Mariano and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2006. Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo. Proceedings of the National Academy of Sciences 103 (38) , pp. 14122-14127. 10.1073/pnas.0604130103

Sleeman, Katherine E., Kendrick, Howard, Ashworth, Alan, Isacke, Clare M. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2006. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Research 8 (R7) 10.1186/bcr1371

Tu, Zheng, Gui, Liming, Wang, Jianliu, Li, Xiaoping, Sun, Pengming and Wei, Lihui 2006. Tumorigenesis of K-ras mutation in human endometrial carcinoma via upregulation of estrogen receptor. Gynecologic Oncology 101 (2) , pp. 274-279. 10.1016/j.ygyno.2005.10.016

2005

Abell, Kathrine, Bilancio, Antonio, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Tiffen, Paul G., Altaparmakov, Anton I., Burdon, Thomas G., Asano, Tomoichiro, Vanhaesebroeck, Bart and Watson, Christine J. 2005. Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. Nature Cell Biology Vol. 7 (4) , pp. 392-398. 10.1038/ncb1242

Buslei, R., Nolde, M., Hofmann, B., Meissner, S., Eyupoglu, I. Y., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Hahnen, E., Kreutzer, J. and Fahlbusch, R. 2005. Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region. Acta Neuropathologica 109 (6) , pp. 589-597.

Craiu, A., Saito, Y., Limon, A., Eppich, H. M., Olson, D. P., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Adams, G. B., Dombkowski, D., Richardson, P., Schlossman, R., Choi, P. S., Grogins, J., O'Connor, P. G., Cohen, K., Attar, E. C., Freshman, J., Rich, R., Mangano, J. A., Gribben, J. G., Anderson, K. C. and Scadden, D. T. 2005. Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood 105 (5) , pp. 2235-2238. 10.1182/blood-2003-12-4399

Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Jonker, J.W., Mesman, E. and Schinkel, A.H. 2005. The Breast Cancer Resistance Protein (BCRP/ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nature Medicine volume (issue) , pp. 127-129. 10.1038/nm1186

Eyupoglu, I. Y., Hahnen, E., Buslei, R., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Savaskan, N. E., Luders, M., Trankle, C., Wick, W., Weller, M., Fahlbusch, R. and Blumcke, I. 2005. Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo. Journal of Neurochemistry 93 (4) , pp. 992-999. 10.1111/j.1471-4159.2005.03098.x

Eyupoglu, I. Y., Hahnen, E., Heckel, A., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, R., Fahlbusch, R. and Blumcke, I. 2005. Malignant glioma-induced neuronal cell death in an organotypic glioma invasion model. Technical note. Journal of Neurosurgery 102 (4) , pp. 738-744. 10.3171/jns.2005.102.4.0738

Jonker, Johan W., Freeman, Jamie, Bolscher, Ellen, Musters, Sandra, Alvi, Azra J., Titley, Ian, Schinkel, Alfred H. and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2005. Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice. Stem Cells 23 (8) , pp. 1059-1065. 10.1634/stemcells.2005-0150

Le Floch, N., Rivat, C., De Wever, O., Bruyneel, E., Mareel, M., Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Gespach, C. 2005. The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3  and c-Jun/AP-1 signaling. The FASEB Journal 19 (1) , pp. 144-146. 10.1096/fj.04-2373fje

Meniel, Valerie, Hay, Trevor, Douglas-Jones, Anthony Gordon, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2005. Mutations in Apc and p53 synergize to promote mammary neoplasia. Cancer Research 65 (24) , pp. 410-6.

Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Janzen, V., Forkert, R., Dombkowski, D. M., Boyd, A. S., Orkin, S. H., Enver, T., Vyas, P. and Scadden, D. 2005. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis. Blood 106 (2) , pp. 477-484. 10.1182/blood-2004-08-2989

Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Griffiths, David Francis Rees, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Winton, Douglas J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2005. Apc deficiency predisposes to renal carcinoma in the mouse. Oncogene 24 , pp. 8205-8210. 10.1038/sj.onc.1208956

Sansom, Owen J., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, van de Wetering, M., Muncan, V., Winton, D. J., Clevers, H. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2005. Cyclin D1 is not an immediate target of β-Catenin following Apc loss in the intestine. Journal of Biological Chemistry 280 (31) , pp. 28463-28467. 10.1074/jbc.M500191200

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Robert B. 2005. The mammary gland “side population”: a putative stem/progenitor cell marker? Journal of Mammary Gland Biology and Neoplasia 10 (1) , pp. 37-47. 10.1007/s10911-005-2539-0

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Signoret, Nathalie, Robertson, David, Tilley, Alan, Hann, Anthony, Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Ding, Yanning, Paterson, Hugh and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2005. Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta. Journal of Cell Science 118 (22) , pp. 5279-5289. 10.1242/jcs.02647

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Titley, I. and Ashworth, A. 2005. An improved definition of mouse mammary epithelial side population cells. Cytotherapy 7 (6) , pp. 497-508. 10.1080/14653240500361145

Sorrell, David A., Szymanowska, Malgorzata, Boutinaud, Marion, Robinson, Claire, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Stein, Torsten, Flint, David J. and Kolb, Andreas F. 2005. Regulation of genes encoding proteolytic enzymes during mammary gland development. Journal of Dairy Research 72 (04) , pp. 433-441. 10.1017/S0022029905001202

Wilson, Catherine Helen, Idziaszczyk, Shelley Alexis, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Guy, Carol, Griffiths, David Francis Rees, Lazda, Edgar Janis, Bayne, Rosemary A. L., Smith, Andrew J. H., Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2005. A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma. Human Molecular Genetics 14 (13) , pp. 1839-1850. 10.1093/hmg/ddi190

2004

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Siapati, Elena K. and Bonnet, Dominique 2004. In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions. Journal of Cell Science 117 (23) , pp. 5655-5664. 10.1242/jcs.01488

Ciani, L., Krylova, O., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Salinas, P. 2004. A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules. Journal of Cell Biology 164 (2) , pp. 243-253. 10.1083/jcb.200309096

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Wayland, M. T., Lee, J., Freeman, T. and Watson, C. J. 2004. Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression. Breast Cancer Research 6 (2) , R92-R109.
file

Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Serpente, N., Cogram, P., Hosking, C. R., Bialucha, C. U., Feller, S. M., Braga, V. M. M., Birchmeier, W. and Fujita, Y. 2004. Rap1 regulates the formation of E-Cadherin-based cell-cell contacts. Molecular and Cellular Biology 24 (15) , pp. 6690-6700. 10.1128/MCB.24.15.6690-6700.2004

Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Reubi, Jean-Claude, Millan, David and Vasey, Paul 2004. Octreotide: an active agent in epithelial ovarian carcinoma? The Lancet Oncology 5 (4) , pp. 251-253. 10.1016/S1470-2045(04)01430-5

Kirby, Denise M., Salemi, Renato, Sugiana, Canny, Ohtake, Akira, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Bell, Katrina M., Kirk, Edwin P., Boneh, Avihu, Taylor, Robert W., Dahl, Hans-Henrik M., Ryan, Michael T. and Thorburn, David R. 2004. NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency. The Journal of Clinical Investigation 114 (6) , pp. 837-845. 10.1172/JCI200420683
file

Milligan, G., Feng, Gui Jie, Ward, R., Sartania, N., Ramsay, D., McLean, A. and Carrillo, J. 2004. G protein-coupled receptor fusion proteins in drug discovery. Current Pharmaceutical Design 10 (17) , pp. 1989-2001. 10.2174/1381612043384295

Murdoch, H., Feng, Gui Jie, Bachner, D., Ormiston, L., White, J. H., Richter, D. and Milligan, G. 2004. Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail. Journal of Biological Chemistry 280 (9) , pp. 8208-8220. 10.1074/jbc.M405215200

Murdoch, H., Milligan, G., Kellett, E., White, J. H. and Feng, Gui Jie 2004. Interactions between G-protein-coupled receptors and periplakin: a selective means to regulate G-protein activation. Biochemical Society Transactions 32 (5) , pp. 878-880. 10.1042/BST0320878

Qiu, J., Takagi, Y., Harada, J., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Moskowitz, M. A., Scadden, D. T. and Cheng, T. 2004. Regenerative response in ischemic brain restricted by p21cip1/waf1. Journal of Experimental Medicine 199 (7) , pp. 937-945. 10.1084/jem.20031385

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Hayes, Anthony Joseph, Gescher, Andreas J., Winton, Douglas J., Peters, Jeffrey M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2004. PPARδ status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene 23 (55) , pp. 8992-8996. 10.1038/sj.onc.1208143

Roberts, M. S., Woods, A. J., Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, van der Sluijs, P. and Norman, J. C. 2004. Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of  αvβ3 and α5β1 integrins. Molecular and Cellular Biology 24 (4) , pp. 1505-1515. 10.1128/MCB.24.4.1505-1515.2004

Shaw, Paul ORCID: https://orcid.org/0000-0002-7467-0619 and Agrawal, R. 2004. Pleurodesis for malignant pleural effusions. Cochrane Database of Systematic Reviews 2004 (1) , CD002916. 10.1002/14651858.CD002916.pub2

Xu, Mingxu, Cheng, Ning, Gui, Liming, Lai, Mouyi, Wang, Ying, Xia, Donglan, Rui, Min, Zhang, Yingmei and Ma, Dalong 2004. The 5′-upstream region of human programmed cell death 5 gene contains a highly active TATA-less promoter that is up-regulated by etoposide. Gene 329 , pp. 39-49. 10.1016/j.gene.2003.12.025

2003

Alvi, Azra J., Clayton, Helen, Joshi, Chirag, Enver, Tariq, Ashworth, Alan, Vivanco, Maria d. M, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2003. Functional and molecular characterisation of mammary side population cells. Breast Cancer Research 5 (1) , R1-R8. 10.1186/bcr547

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Corti, C., Ferraguti, F. and Xuereb, J.H. 2003. Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells. Journal of Biological Chemistry Vol. 2 (No.35) , pp. 33105-33119. 10.1074/jbc.M212380200

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J. 2003. Microarray analysis of the involution switch. Journal of Mammary Gland Biology and Neoplasia 8 (3) , pp. 309-319. 10.1023/B:JOMG.0000010031.53310.92

Dajani, Rana, Fraser, Elizabeth, Roe, S. Mark, Yeo, Margaret, Good, Valerie M., Thompson, Vivienne, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Pearl, Laurence H. 2003. Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex. The EMBO Journal 22 (3) , pp. 494-501. 10.1093/emboj/cdg068

Dixon, P. F., Avery, S., Chambers, E., Feist, S., Mandhar, H., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Stone, D. M., Stremmen, H. K., Thurlow, J. K., Lui, C. Tsin-yee and Way, K. 2003. Four years of monitoring for viral haemorrhagic septicaemia virus in marine waters around the United Kingdom. Disease of Aquatic Organisms 54 (3) , pp. 175-186. 10.3354/dao054175

Feng, Gui-Jie, Kellett, Elaine, Scorer, Carol A., Wilde, Jonathan, White, Julia H. and Milligan, Graeme 2003. Selective interactions between helix VIII of the human μ-opioid receptors and the C terminus of periplakin disrupt G protein activation. Journal of Biological Chemistry 278 (35) , pp. 33400-33407. 10.1074/jbc.M305866200

Jones, Gareth E., Prigmore, Elena, Calvez, Ronan, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Dunn, Graham A., Hirsch, Emilio, Wymann, Matthias P. and Ridley, Anne J. 2003. Requirement for PI 3-kinase γ in macrophage migration to MCP-1 and CSF-1. Experimental Cell Research 290 (1) , pp. 120-131. 10.1016/S0014-4827(03)00318-5

Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Goldstein, David, Kurtovic, Jelica, Keogh, Gregory and Riordan, Stephen M. 2003. Compression of liver parenchyma by a malignant hepatic cyst a previously unreported manifestation of metastatic gastric cancer [Letter]. The American Journal of Gastroenterology 98 (5) , pp. 1211-1213. 10.1016/S0002-9270(03)00170-9

Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Ryan, Mary and Friedlander, Michael 2003. Carboplatin hypersensitivity reactions: re-treatment with cisplatin desensitisation. Gynecologic Oncology 89 (1) , pp. 112-115. 10.1016/S0090-8258(03)00066-0

Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496 and Vasey, P. A. 2003. New directions in testicular cancer; molecular determinants of oncogenesis and treatment success. European Journal of Cancer 39 (2) , pp. 147-156. 10.1016/S0959-8049(02)00612-3

Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496 and Vasey, Paul A 2003. Part II: Testicular cancer - management of advanced disease. The Lancet Oncology 4 (12) , pp. 738-747. 10.1016/S1470-2045(03)01279-8

Kritikou, Ekaterini A., Sharkey, Andrew, Abell, Kathrine, Came, Paul J., Anderson, Elizabeth, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J. 2003. A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development 130 (15) , pp. 3459-3468. 10.1242/dev.00578

Meniel, Valerie and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2003. Wnt-Cadherin connections in normal and neoplastic mammary epithelium. Journal of Mammary Gland Biology and Neoplasia 8 (4) , pp. 435-447. 10.1023/B:JOMG.0000017430.12210.37

Milligan, G., Ward, Richard J., Feng, Gui-Jie, Carrillo, Juan J. and McLean, Alison J. 2003. Using receptor-G-Protein chimeras to screen for drugs. Bradshaw, Ralph A. and Dennis, Edward A., eds. Handbook of Cell Signaling, Vol. 1. San Diego: Academic Press, pp. 619-621.

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Ashworth, Alan 2003. Stem cells and breast cancer: A field in transit. Nature Reviews Cancer 3 , pp. 832-844. 10.1038/nrc1212

2002

Adams, G. B., Chabner, K. T., Foxall, R. T., Weibrecht, K. W., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Dombkowski, D., Fallon, R., Poznansky, M. C. and Scadden, D. T. 2002. Heterologous cells cooperate to augment stem cell migration, homing, and engraftment. Blood 101 (1) , pp. 45-51. 10.1182/blood-2002-02-0486

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2002. lkB kinase alpha: a link in the chain of the mammary cycle. Breast Cancer Research 4 , 173. 10.1186/bcr446

Cullingworth, Jan, Hooper, Martin L., Harrison, David J., Mason, John O., Sirard, Christian, Patek, Charles E. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2002. Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes. Oncogene 21 (30) , pp. 4696-4701. 10.1038/sj.onc.1205673

Ding, Yanning and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2002. Wnt signal transduction: kinase cogs in a nano-machine? Trends in Biochemical Sciences 27 (7) , pp. 327-329. 10.1016/S0968-0004(02)02137-0

Feng, Gui Jie, Cavalli, Antonella and Milligan, Graeme 2002. Engineering a V2 vasopressin receptor agonist- and regulator of G-protein-signaling-sensitive G protein. Analytical Biochemistry 300 (2) , pp. 212-220. 10.1006/abio.2001.5448

Franca-Koh, Jonathan, Yeo, Margaret, Fraser, Elizabeth, Young, Neville and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2002. The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP. Journal of Biological Chemistry , pp. 43844-43848. 10.1074/jbc.M207265200

Fraser, Elizabeth, Young, N., Dajani, R., Franca-Koh, J., Ryves, William Jonathan, Williams, R. S. B., Yeo, M., Webster, M.-T., Richardson, C., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Pearl, L. H., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2002. Identification of the Axin and Frat binding region of glycogen synthase kinase-3. Journal of Biological Chemistry 277 (3) , pp. 2176-2185. 10.1074/jbc.M109462200

Gallagher, Ronald C. J., Hay, Trevor, Meniel, Valerie, Naughton, Catherine, Anderson, Thomas J., Shibata, Hiroyuki, Ito, Masaki, Clevers, Hans, Noda, Tetsuo, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Mason, John O. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2002. Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. Oncogene 21 (42) , pp. 6446-6457. 10.1038/sj.onc.1205892

Harper, M. J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2002. Low frequency ultrasonic propagation through fibre reinforced, polymer composites. Ultrasonics 40 (1-8) , pp. 555-560. 10.1016/S0041-624X(02)00169-5

Menke, Aswin L., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Leitch, Andrea, Ijpenberg, Annemeike, Williamson, Kathy A., Spraggon, Lee, Harrison, David J. and Hastie, Nicholas D. 2002. Genetic interactions between the Wilms' tumor 1 gene and the p53 gene. Cancer Research 62 (22) , pp. 6615-6620.

Morse, Nerys R., Meniel, Valerie and Waters, Raymond 2002. Photoreactivation of UV-induced cyclobutane primidine dimers in the MFA2 gene of S. cerevisiae. Nucleic Acids Research 30 (8) , pp. 1799-1807. 10.1093/nar/30.8.1799

2001

Cheng, T., Shen, H., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Stier, S. and Scadden, D. T. 2001. Transforming growth factor β1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1or p27Kip1. Blood 98 (13) , pp. 3643-3649. 10.1182/blood.V98.13.3643

Dajani, Rana, Fraser, Elizabeth, Roe, S. Mark, Young, Neville, Good, Valerie, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Pearl, Laurence H. 2001. Crystal structure of glycogen synthase kinase 3β : structural basis for phosphate-primed substrate specificity and autoinhibition. Cell 105 (6) , pp. 721-732. 10.1016/S0092-8674(01)00374-9

Han, Wenling, Lou, Yaxin, Tang, Junmin, Zhang, Yingmei, Chen, Yingyu, Li, Ying, Gu, Weifeng, Hueng, Jiaqiang, Gui, Liming, Tang, Yan, Li, Feng, Song, Quansheng, Di, Chunhui, Wang, Lu, Shi, Qun, Sun, Ronghua, Xia, Donglan, Rui, Min, Tang, Jian and Ma, Dalong 2001. Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. Biochemical Journal 357 (1) , pp. 127-135. 10.1042/0264-6021:3570127

Heisenberg, C. -P., Houart, Corinne, Take-uchi, Masaya, Rauch, Gerd-Jörg, Young, Neville, Coutinho, Pedro, Masai, Ichiro, Caneparo, Luca, Concha, Miguel L., Geisler, Robert, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Wilson, Stephen W. and Stemple, Derek L. 2001. A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes & Development 15 (11) , pp. 1427-1434. 10.1101/gad.194301

Hodges, Angela K., Li, Shaowei, Maynard, Julie Helen, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Braverman, Richard, DeClue, Jeffrey E., Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 and Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 2001. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin. Human Molecular Genetics 10 (25) , pp. 2899-9205. 10.1093/hmg/10.25.2899

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Maynard, Julie Helen, Patel, A., Clifford, S. C., Morrissey, C., Maher, E. R., Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 and Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 2001. Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas. British Journal of Cancer 85 , pp. 1226-1230. 10.1054/bjoc.2001.2072

Patel, Girish Khandubhai and Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144 2001. Rifampicin-induced lupus erythematosus. Clinical and Experimental Dermatology 26 (3) , pp. 260-262. 10.1046/j.1365-2230.2001.00809.x

Patel, Girish, Taylor, D. and Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144 2001. No need for sunscreen or occlusive dressings for benign naevi during routine phototherapy [Letter]. Photodermatology, Photoimmunology & Photomedicine 17 (5) , pp. 245-246. 10.1111/j.1600-0781.2001.170508.x

Sansom, Owen J., Stark, Lesley A., Dunlop, Malcolm G. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2001. Suppression of intestinal and mammary neoplasia by lifetime administration of aspirin in ApcMin/+ and ApcMin/+, Msh2-/- mice. Cancer Research 61 , pp. 7060-7064.

Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Toft, Neil J., Winton, Douglas J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2001. Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner. Oncogene 20 (27) , pp. 3580-3584. 10.1038/sj.onc.1204449

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2001. Wnt signaling and mammary tumorigenesis. Journal of Mammary Gland Biology and Neoplasia 6 (1) , pp. 37-52.

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Leiper, K., Tootle, R., McCloskey, P., O'Hare, M. J. and Hodgson, H. 2001. Immortalisation of human hepatocytes by temperature-sensitive SV40 large-T antigen. In Vitro Cellular and Developmental Biology - Animal 37 (3) , pp. 166-168. 10.1290/1071-2690(2001)037<0166:IOHHBT>2.0.CO;2

Strathdee, Gordon, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Sim, Alyson, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Brown, Robert 2001. A role for mismatch repair in control of DNA ploidy following DNA damage. Oncogene 20 (15) , pp. 1923-1927. 10.1038/sj.onc.1204276

Twelves, Chris and Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496 2001. Oral uracil-tegafur: an alternative to intravenous 5-fluorouracil? Expert Opinion on Pharmacotherapy 2 (9) , pp. 1495-1505. 10.1517/14656566.2.9.1495

2000

Brain, Katherine Emma ORCID: https://orcid.org/0000-0001-9296-9748, Gray, Jonathon, Norman, Paul, France, Elizabeth, Anglim, Cathy, Barton, Garry, Parsons, Evelyn Patricia, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Sweetland, Helen Margaret, Tischkowitz, Marc, Myring, Jenny, Stansfield, Kate, Webster, David, Gower-Thomas, Kate, Daoud, Raouf, Gateley, Chris, Montpenny, Ian, Singhal, Hemant, Branston, Lucy, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348, Roberts, Elizabeth, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867, Cohen, David, Rogers, Cerilan, Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 and Harper, Peter Stanley 2000. Randomized trial of a specialist genetic assessment service for familial breast cancer. Journal of the National Cancer Institute 92 (16) , pp. 1345-1351. 10.1093/jnci/92.16.1345

Chapman, Rachel S., Duff, Eleanor K., Lourenco, Paula C., Tonner, Elizabeth, Flint, David J., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Watson, Christine J. 2000. A novel role for IRF-1 as a suppressor of apoptosis. Oncogene 19 (54) , pp. 6386-6391. 10.1038/sj.onc.1204016

Chapman, Rachel S., Lourenco, Paula, Tonner, Elizabeth, Flint, David, Selbert, Stefan, Takeda, Kyoshi, Akira, Shizuo, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Watson, Christine J. 2000. The role of Stat3 in apoptosis and mammary gland involution. Mol, Jan A. and Clegg, Roger A., eds. Biology of the Mammary Gland, Advances in Experimental Medicine and Biology, Kluwer, pp. 129-138. (10.1007/0-306-46832-8_16)

Cheng, Tao, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Dombkowski, David, Stier, Sebastian and Scadden, David T. 2000. Stem cell repopulation efficiency but not pool size is governed by p27 (kip1). Nature Medicine 6 , pp. 1235-1240. 10.1038/81335

Cheng, Tao, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Shen, Hongmei, Yang, Yong-Guang, Dombkowski, David, Sykes, Megan and Scadden, David T. 2000. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287 (5459) , pp. 1804-1808. 10.1126/science.287.5459.1804

Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2000. Manipulating the germline: Its impact on the study of carcinogenesis. Carcinogenesis 21 (3) , pp. 435-441. 10.1093/carcin/21.3.435

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Heeley, JoannaLL., Chapman, Rachel, Aillet, Fabienne, Hay, Ronald T., Wyllie, Andrew and Watson, Christine J. 2000. NF-kappa B inhibits apoptosis in murine mammary epithelia. Journal of Biological Chemistry 275 (17) , pp. 12737-12742. 10.1074/jbc.275.17.12737

Gordon, K., Binas, B., Chapman, R. S., Kurian, K. M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Clark, A. J., Lane, E. B. and Watson, C. J. 2000. A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Research 2 , pp. 222-235. 10.1186/bcr57
file

MacKenzie, Alasdair, Payne, Catherine, Boyle, Shelagh, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Quinn, John P. 2000. The human preprotachykinin-A gene promoter has been highly conserved and can drive human-like marker gene expression in the adult mouse CNS. Molecular and Cellular Neuroscience 16 (5) , pp. 620-630. 10.1006/mcne.2000.0902

Naylor, S., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Robertson, D., Gusterson, B. A., Edwards, P. A. and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2000. Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium. Journal of Cell Science 113 (12) , pp. 2129-2138.

Nunez, Fatima, Chipchase, Michael D., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Melton, David W. 2000. Nucleotide excision repair gene (ERCC1) deficiency causes G2 arrest in hepatocytes and a reduction in liver binucleation: The role of p53 and p21. Faseb Journal 14 (9) , pp. 1073-1082.

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Maynard, Julie Helen, Patel, Amit, Hodges, Angela, von Deimling, Andreas, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2000. Molecular analysis of the TSC1 and TSC2 tumour suppressor genes in sporadic glial and glioneuronal tumours. Human Genetics 107 (4) , pp. 350-356. 10.1007/s004390000390

Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2000. P53 null mice: damaging the hypothesis? Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 452 (2) , pp. 149-162. 10.1016/S0027-5107(00)00089-0

Sarkar, L., Cobourne, M., Naylor, S., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Sharpe, P. T. 2000. Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development. Proceedings of the National Academy of Sciences of the United States of America 97 (9) , pp. 4520-4524. 10.1073/pnas.97.9.4520

Toft, Neil J., Sansom, Owen J., Brookes, Roger A., Arends, Mark J., Wood, Michelle, Margison, Geoffrey P., Winton, Douglas J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2000. In vivo administration of O6-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine. Carcinogenesis 21 (4) , pp. 593-598.

Webster, M. T., Rozycka, M., Sara, Elizabeth, Davis, E., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Young, N., Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Wooster, R. 2000. Sequence variants of the Axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding. Genes Chromosomes and Cancer 28 (4) , pp. 443-453. 10.1002/1098-2264(200008)28:4<443::AID-GCC10>3.0.CO;2-D

1999

Feng, Gui-Jie, Goodridge, Helen S., Harnett, Margaret M., Wei, Xiao Qing, Nikolaev, Andrei V., Higson, Adrian P. and Liew, Foo -Y. 1999. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. Journal of Immunolgy 163 (12) , pp. 6403-6412.

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 1999. Wnt signalling in mammalian development and cancer. Cancer and Metastasis Reviews 18 (2) , pp. 215-230. 10.1023/A:1006369223282

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Fraser, Elizabeth, Paterson, Hugh, Naylor, Stuart, Cook, David, Jayatilake, Hiran, Fryer, Lee G., Hutchinson, Lisa, Fry, Michael J. and Dale, Trevor C. 1999. Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO Journal 18 (10) , pp. 2823-2835. 10.1093/emboj/18.10.2823

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Leiper, K., Floyd, D., Mobberley, M., Ryder, T., Selden, C., Roberts, Eve A. and Hodgson, H. 1999. Behavior of a cell line derived from normal human hepatocytes on non-physiological and physiological-type substrates: Evidence for enhancement of secretion of liver-specific proteins by a three-dimensional growth pattern. In Vitro Cellular and Developmental Biology - Animal 35 (1) , pp. 22-32. 10.1007/s11626-999-0040-6

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Titley, J., Paterson, H., Perusinghe, N., Clarke, C. and O'Hare, M. J. 1999. Differentiation of separated mouse mammary luminal epithelial and myoepithelial cells cultured on EHS matrix analyzed by indirect immunofluorescence of cytoskeletal antigens. Journal of Histochemistry & Cytochemistry 47 (12) , pp. 1513-1524. 10.1177/002215549904701203

1998

McInnes, Iain B., Leung, Bernard P., Feng, Gui-Jie, Sturrock, Roger D., Field, Max and Foo, Y. Liew 1998. Reply to - a role for IL-15 in rheumatoid arthritis? Nature Medicine 4 , p. 643. 10.1038/nm0698-643b

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Titley, J. and O'Hare, M. J. 1998. Clonal characterization of mouse mammary luminal epithelial and myoepithelial cells separated by fluorescence-activated cell sorting. In Vitro Cellular and Developmental Biology - Animal 34 (9) , pp. 711-721. 10.1007/s11626-998-0067-0

1997

Dixon, P.F., Feist, S., Kehoe, E., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Stone, D.M. and Way, K. 1997. Isolation of viral haemorrhagic septicaemia virus from Atlantic herring Clupea harengus from the Atlantic herring Clupea harengus from the English channel. Diseases of Aquatic Organisms 30 (2) , pp. 81-89.

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Dixon, P. F. 1997. Stability of nine viral haemorrhagic septicaemia virus (VHSV) isolates in seawater. Bulletin of the European Association of Fish Pathologists 17 (1) , pp. 31-36.
file

1996

Huang, F. P., Feng, Gui Jie, Lindop, G., Stott, D. I. and Liew, F. W. 1996. The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRLMP-lprlpr mice. Journal of Experimental Medicine 183 (4) , pp. 1447-1459. 10.1084/jem.183.4.1447

1990

Millar, J. B., McGowan, C. H., Lenaers, G., Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496 and Russell, P. 1990. p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. Embo Journal 10 (13) , pp. 5610-5621.

1989

Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496 and Jones, N. C. 1989. Mammalian cAMP-responsive element can activate transcription in yeast and binds a yeast factor(s) that resembles the mammalian transcription factor ATF. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 86 (7) , pp. 2176-2180.

1988

Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Moreno, Sergio, Nurse, Paul and Jones, Nicholas C. 1988. Expression of the SV40 promoter in fission yeast: identification and characterization of an AP-1-like factor. Cell 53 (4) , pp. 659-667. 10.1016/0092-8674(88)90581-8

1985

Zhao, Dayao, Feng, Gui-Jie, Wu, Xiru and Zuo, Qihua 1985. Seizures induced by intraventricular microinjection of ionised cobalt in the rat -- a new experimental model of epilepsy. Brain Research 342 (2) , pp. 323-329. 10.1016/0006-8993(85)91132-1

This list was generated on Thu Mar 28 20:00:10 2024 GMT.