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Number of items at this level: 287.

2019

Flanagan, Dustin J, Vincan, Elizabeth and Phesse, Toby J. 2019. Wnt signaling in cancer: not a binary ON:OFF switch. Cancer Research 10.1158/0008-5472.CAN-19-1362
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French, Rhiannon and Tornillo, Giusy 2019. Heterogeneity of mammary stem cells. Advances in Experimental Medicine and Biology 1169 , pp. 119-140. 10.1007/978-3-030-24108-7_7

Jimenez-Pascual, Ana and Siebzehnrubl, Florian A 2019. Fibroblast growth factor receptor functions in glioblastoma. Cells 8 (7) , 715. 10.3390/cells8070715
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Kannen, Vinicius, Parry, Lee and Martin, Francis L. 2019. Phages enter the fight against colorectal cancer. Trends in Cancer , -. 10.1016/j.trecan.2019.08.002
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May, Stephanie, McDermott, Grace, Marchesi, Julian and Parry, Lee 2019. Impact of black raspberries on the normal and malignant Apc deficient murine gut microbiome. Journal of Berry Research 10.3233/JBR-180372
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Menendez Gonzalez, Juan Bautista, Sinnadurai, Samantha, Gibbs, Alex, Thomas, Leigh-Anne, Konstantinou, Maria, Garcia Valverde, Alfonso, Boyer, Magali, Wang, Zhengke, Boyd, Ashleigh S., Blair, Allison, Morgan, Rhys G. and Rodrigues, Neil P. 2019. Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. Scientific Reports 9 , 12212. 10.1038/s41598-019-48589-0
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Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R., Smalley, Matthew J. and Clarke, Alan R. 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19 , 677. 10.1186/s12885-019-5867-y
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Young, Madeleine, May, Stephanie, Damo, Angelos, Young, So Yoon, Man-Wook, Hur, Wojiech, Swat and Parry, Lee 2019. Epigenetic regulation of Dlg1, via Kaiso, alters mitotic spindle polarity and promotes intestinal tumourigenesis. Molecular Cancer Research 17 (3) , pp. 686-696. 10.1158/1541-7786.MCR-18-0280
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2018

Burke, Zoe D., Reed, Karen Ruth, Yeh, Sheng-Wen, Meniel, Valerie S., Sansom, Owen J., Clarke, Alan R. and Tosh, David 2018. Spatiotemporal regulation of liver development by the Wnt/β- catenin pathway. Scientific Reports 8 , 2735. 10.1038/s41598-018-20888-y
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Flanagan, Dustin, Austin, Chloe, Vincan, Elizabeth and Phesse, Toby 2018. Wnt Signalling in gastrointestinal epithelial stem cells. Genes 9 (4) , 178. 10.3390/genes9040178
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Greenow, Kristy, Zverev, Matthew, May, Stephanie, Kendrick, Howard, Williams, Geraint, Phesse, Toby and Parry, Lee 2018. Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis. Oncotarget 9 (92) , pp. 36430-36443. 10.18632/oncotarget.26335
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Hill, William 2018. Heterotypic cell-cell interactions between KrasG12D cells and normal neighbours in early pancreatic cancer. PhD Thesis, Cardiff University.
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Hoang-Minh, Lan B, Siebzehnrubl, Florian, Yang, Changlin, Suzuki-Hatano, Silveli, Dajac, Kyle, Loche, Tyler, Andrews, Nicholas, Schmoll Massari, Michael, Patel, Jaimin, Amin, Krisha, Vuong, Alvin, Jimenez Pascual, Ana, Kubilis, Paul, Garrett, Timothy J, Moneypenny, Craig, Pacak, Christina A, Huang, Jianping, Sayour, Elias J, Mitchell, Duane A, Sarkisian, Matthew R, Reynolds, Brent A and Deleyrolle, Loic P 2018. Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. EMBO Journal 37 (22) , e98772. 10.15252/embj.201798772
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May, Stephanie, Owen, Heather, Phesse, Toby, Greenow, Kristy, Jones, Gareth-Rhys, Blackwood, Adam, Cook, Peter C., Towers, Christopher, Gallimore, Awen, Williams, Geraint T., Sturzl, Michael, Britzen-Laurent, Nathalie, Sansom, Owen J., MacDonald, Andrew S., Bird, Adrian P., Clarke, Alan R. and Parry, Lee 2018. Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation. Journal of Pathology 245 (3) , pp. 270-282. 10.1002/path.5074
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Morgan, Huw 2018. Elucidating the role of TGFβ signalling in drug resistant Hh driven cancers. PhD Thesis, Cardiff University.
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Pearson, Helen, Li, Jason, Meniel, Valerie, Fennell, Christina, Waring, Paul, Montgomery, Karen, Rebello, Richard, Macpherson, Arthi, Koushyar, Sarah, Furic, Luc, Cullinane, Carleen, Clarkson, Richard, Smalley, Matthew, Simpson, Kaylene, Phesse, Toby, Shepherd, Peter, Humbert, Patrick, Sansom, Owen and Phillips, Wayne 2018. Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth. Cancer Discovery 8 (6) , pp. 764-779. 10.1158/2159-8290.CD-17-0867
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Piggott, Luke, Silva, Ana, Robinson, Timothy, Santiago-Gomez, A., Simoes, B. M., Becker, M., Fichtner, I., Andera, L., Young, P., Morris, C., Barret-Lee, P., Alchami, F., Piva, M., Vivanco, M. d. M., Clarke, R. B., Gee, Julia M. W. and Clarkson, Richard 2018. Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through post-translational downregulation of c-FLIP. Clinical Cancer Research 24 (10) , pp. 2452-2463. 10.1158/1078-0432.CCR-17-1381
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Prim Padilha, Ana 2018. Molecular and functional characterization of the role of Foxp3+ regulatory T (Treg) cells in the development of intestinal cancer. PhD Thesis, Cardiff University.
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Puig Barbe, Aleix 2018. A network of bHLH factors controls self-renewal and bipotential differentiation in the Drosophila intestine. PhD Thesis, Cardiff University.
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Siebzehnrubl, Florian A., Raber, Kerstin A., Urbach, Yvonne K., Schulze-Krebs, Anja, Canneva, Fabio, Moceri, Sandra, Habermeyer, Johanna, Achoui, Dalila, Gupta, Bhavana, Steindler, Dennis A., Stephan, Michael, Nguyen, Huu Phuc, Bonin, Michael, Riess, Olaf, Bauer, Andreas, Aigner, Ludwig, Couillard-Despres, Sebastien, Paucar, Martin Arce, Svenningsson, Per, Osmand, Alexander, Andreew, Alexander, Zabel, Claus, Weiss, Andreas, Kuhn, Rainer, Moussaoui, Saliha, Blockx, Ines, Van der Linden, Annemie, Cheong, Rachel Y., Roybon, Laurent, Petersén, Åsa and von Hörsten, Stephan 2018. Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition. Proceedings of the National Academy of Sciences 115 (37) , E8765-E8774. 10.1073/pnas.1807962115
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Tornillo, Giusy, Knowlson, Catherine, Kendrick, Howard, Cooke, Joe, Hasan, Mirza, Aurrekoetxea-Rodriguez, Iskander, dM Vivanco, Maria, Buckley, Niamh E., Grigoriadis, Anita and Smalley, Matthew 2018. Dual mechanisms of LYN kinase dysregulation drive aggressive behaviour in breast cancer cells. Cell Reports 25 (13) , pp. 3674-3692. 10.1016/j.celrep.2018.11.103
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Vincan, Elizabeth, Schwab, Renate H.M., Flanagan, Dustin J., Moselen, Jean M., Tran, Bang M., Barker, Nick and Phesse, Toby 2018. The central role of Wnt signaling and organoid technology in personalizing anticancer therapy. Progress in Molecular Biology and Translational Science 153 , pp. 299-319. 10.1016/bs.pmbts.2017.11.009
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2017

Badder, Luned 2017. Developing stem-cell containing organoids as a pre-clinical model for colorectal cancer therapeutics. PhD Thesis, Cardiff University.
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Berenjeno, Inma M., Piñeiro, Roberto, Castillo, Sandra D., Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M., Meniel, Valerie, Birkbak, Nicolai J., Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E. R., Montgomery, Karen G., Moniz, Larissa S., Scudamore, Cheryl L., Phillips, Wayne A., Semple, Robert K., Clarke, Alan, Swanton, Charles and Vanhaesebroeck, Bart 2017. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications 8 (1) , 1773. 10.1038/s41467-017-02002-4
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Flanagan, Dustin J, Barker, Nicholas, Nowell, Cameron, Clevers, Hans, Ernst, Matthias, Phesse, Toby and Vincan, Elizabeth 2017. Loss of the Wnt Receptor Frizzled7 in the Gastric Epithelium is deleterious and triggers rapid repopulation in vivo. Disease Models & Mechanisms 10 (8) , pp. 971-980. 10.1242/dmm.029876
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Hwang, Ho Sik, Parfitt, Geraint J., Brown, Donald J. and Jester, James V. 2017. Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD). Experimental Eye Research 163 , pp. 37-45. 10.1016/j.exer.2017.02.008
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Konstantinou, Maria 2017. Characterising In-111-anti-γH2AX-TAT in targeting the DNA damage signal associated with Wnt activated Colorectal Cancer. PhD Thesis, Cardiff University.
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Lanfredini, Simone, Olivero, Carlotta, Borgogna, Cinzia, Calati, Federica, Powell, Kathryn, Davies, Kelli-Jo, De Andrea, Marco, Harries, Sarah, Tang, Hiu, Pfister, Herbert, Gariglio, Marisa and Patel, Girish K 2017. HPV8 field cancerization in a transgenic mouse model is due to Lrig1+Keratinocyte stem cell expansion. Journal of Investigative Dermatology 137 (10) , pp. 2208-2216. 10.1016/j.jid.2017.04.039
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May, Stephanie, Evans, Samantha and Parry, Lee 2017. Organoids, organs-on-chips and other systems, and microbiota. Emerging Topics in Life Sciences 1 (4) , pp. 385-400. 10.1042/ETLS20170047
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Menendez Gonzalez, Juan Bautista 2017. Exploring the role of GATA2 in normal and malignant haematopoiesis. PhD Thesis, Cardiff University.
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Mohamed, Noha-Ehssan 2017. Characterizing the roles of APC2 protein in ovarian homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
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Planells-Palop, Vicente, Hazazi, Ali, Feichtinger, Julia, Jezkova, Jana, Thallinger, Gerhard, Alsiwiehri, Naif O., Almutairi, Mikhlid, Parry, Lee, Wakeman, Jane A. and McFarlane, Ramsay J. 2017. Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Molecular Cancer 16 (1) 10.1186/s12943-017-0653-4
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Yeo, Syn Kok, French, Rhiannon, Filomena, Spada and Clarkson, Richard 2017. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment 162 (3) , pp. 465-477. 10.1007/s10549-017-4149-0
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2016

Abraham, Thomas, Barbier, Michaël, Jaensch, Steffen, Cornelissen, Frans, Vidic, Suzana, Gjerde, Kjersti, de Hoogt, Ronald, Graeser, Ralph, Gustin, Emmanuel, Chong, Yolanda T. and Smalley, Matthew J. 2016. Ellipsoid segmentation model for analyzing light-attenuated 3D confocal image stacks of fluorescent multi-cellular spheroids. PLoS ONE 11 (6) , e0156942. 10.1371/journal.pone.0156942
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Estrada, Marta F., Rebelo, Sofia P., Davies, Emma J., Pinto, Marta T., Pereira, Hugo, Santo, Vítor E., Smalley, Matthew John, Barry, Simon T., Gualda, Emilio J., Alves, Paula M., Anderson, Elizabeth and Brito, Catarina 2016. Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression. Biomaterials 78 , pp. 50-61. 10.1016/j.biomaterials.2015.11.030
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Fang, Hsiao Yu, Martinez-Arias, Alfonso and De Navascues Melero, Joaquin 2016. Autocrine and paracrine Wingless signalling in the Drosophila midgut by both continuous gradient and asynchronous bursts of wingless expression. F1000Research 5 , 317. 10.12688/f1000research.8170.1
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Flanagan, Dustin J., Schwab, Renate H. M., Tran, Bang M., Phesse, Toby J. and Vincan, Elizabeth 2016. Isolation and culture of adult intestinal, gastric, and lver organoids for cre-recombinase-mediated gene deletion. Methods in Molecular Biology, Humana Press, pp. 1-11. (10.1007/7651_2016_14)
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Griessinger, E., Dos Anjos Afonso, Fernando, Vargaftig, J., Taussig, D., Lassailly, F., Prebet, T., Imbert, V., Nebout, M., Vey, N., Chabannon, C., Filby, A., Bollet-Quivogne, F., Gribben, J. G., Peyron, J. F. and Bonnet, D. 2016. Frequency and dynamics of leukemia-initiating cells during short-term ex vivo culture informs outcomes in acute myeloid leukemia patients. Cancer Research 76 (8) , pp. 2082-2086. 10.1158/0008-5472.CAN-15-2063

Hollins, Andrew John and Parry, Lee 2016. Long-term culture of intestinal cell progenitors: an overview of their development, application, and associated technologies. Current Pathobiology Reports 4 (4) , pp. 209-219. 10.1007/s40139-016-0119-1
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Jurado, Jaime, De Navascues Melero, Joaquin and Gorfinkiel, Nicole 2016. α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction. Journal of Cell Science , jcs.193268. 10.1242/jcs.193268
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Parfitt, Geraint J., Brown, Donald J. and Jester, James V. 2016. Transcriptome analysis of aging mouse meibomian glands. Molecular Vision 22 , pp. 518-527.

Reed, Karen Ruth, Song, Fei, Young, Madeleine, Hassan, N., Antoine, A. J., Gemici, Nesibe-Princess B, Clarke, Alan Richard and Jenkins, J. R. 2016. Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. Oncotarget 7 (32) , pp. 51665-51673. 10.18632/oncotarget.10076
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Togel, L., Nightingale, R.-, Chueh, A.. C., Jayachandran, A., Tran, Huynh, Phesse, Toby, Wu, R., Sieber, O. M., Arango, D., Dhillon, A. S., Dawson, M. A., Diez-Dacal, B., Gahman, T. C., Filippakopoulos, P., Shiau, A. K. and Mariadason, J. M. 2016. Dual targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Molecular Cancer Therapeutics 15 (6) , pp. 1217-1226. 10.1158/1535-7163.MCT-15-0724

Zhao, Chuntao, Deng, Yaqi, Liu, Lei, Yu, Kun, Zhang, Liguo, Wang, Haibo, He, Xuelian, Wang, Jincheng, Lu, Changqing, Wu, Laiman N, Weng, Qinjie, Mao, Meng, Li, Jianrong, van Es, Johan H, Xin, Mei, Parry, Lee, Goldman, Steven A, Clevers, Hans and Lu, Q. Richard 2016. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nature Communications 7 , 10883. 10.1038/ncomms10883
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2015

Freeman, Jamie, Smith, David, Latinkic, Branko, Ewan, Kenneth Burnside Ramsay, Samuel, Lee, Zollo, Massimo, Marino, Natascia, Tyas, Lorraine, Jones, Nick and Dale, Trevor Clive 2015. A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. Molecular Cancer 14 (1) , 206. 10.1186/s12943-015-0475-1
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Huels, D. J., Ridgway, R. A., Radulescu, S., Leushacke, M., Campbell, A. D., Biswas, S., Leedham, S., Serra, S., Chetty, R., Moreaux, G., Parry, Lee, Matthews, James, Song, F., Hedley, A., Kalna, G., Ceteci, F., Reed, Karen Ruth, Meniel, Valerie, Maguire, A., Doyle, B., Soderberg, O., Barker, N., Watson, A., Larue, L., Clarke, Alan Richard and Sansom, O. J. 2015. E-cadherin can limit the transforming properties of activating  β‐catenin mutations. EMBO Journal 34 (16) 10.15252/embj.201591739
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Iglesias, Juan Manuel, Cairney, Claire J., Ferrier, Roderick K., McDonald, Laura, Soady, Kelly, Kendrick, Howard, Pringle, Marie-Anne, Morgan, Reginald O., Martin, Finian, Smalley, Matthew John, Blyth, Karen and Stein, Torsten 2015. Annexin A8 identifies a subpopulation of transiently quiescent c-Kit positive luminal progenitor cells of the ductal mammary epithelium. Plos One 10 (3) , e0119718. 10.1371/journal.pone.0119718
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Jester, James V., Parfitt, Geraint J and Brown, Donald J. 2015. Meibomian gland dysfunction: hyperkeratinization or atrophy? BMC Ophthalmology 15 (S1) , 156. 10.1186/s12886-015-0132-x

Leal, Maria del Pilar Camacho, Sciortino, Marianna, Tornillo, Giusy, Colombo, Shana, Defilippi, Paola and Cabodi, Sara 2015. p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis. Gene 562 (1) , pp. 1-7. 10.1016/j.gene.2015.02.027

Lio, Ka Ian 2015. Characterising the role of Cbx3/HP1γ in normal intestinal homeostasis and tumourigenesis. PhD Thesis, Cardiff University, School of Biosciences.
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Meniel, Valerie, Megges, M., Young, Madeleine, Cole, A., Sansom, O. J. and Clarke, Alan Richard 2015. Apc and p53 interaction in DNA damage and genomic instability in hepatocytes. Oncogene 34 , pp. 4118-4129. 10.1038/onc.2014.342

Miraki-Moud, Farideh, Ghazaly, Essam, Ariza-McNaughton, Linda, Hodby, Katharine A., Clear, Andrew, Dos Anjos Afonso, Fernando, Liapis, Konstantinos, Grantham, Marianne, Sohrabi, Fareeda, Cavenagh, Jamie, Bomalaski, John S., Gribben, John G., Szlosarek, Peter W., Bonnet, Dominique and Taussig, David C. 2015. Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo. Blood 125 (26) , pp. 4060-4068. 10.1182/blood-2014-10-608133

Parfitt, Geraint J, Geyfman, Mikhail, Xie, Yilu and Jester, James V. 2015. Characterization of quiescent epithelial cells in mouse meibomian glands and hair follicle/sebaceous glands by immunofluorescence tomography. Journal of Investigative Dermatology 135 (4) , pp. 1175-1177. 10.1038/jid.2014.484

Parfitt, Geraint J, Kavianpour, Behdad, Wu, Karen L., Xie, Yilu, Brown, Donald J. and Jester, James V. 2015. Immunofluorescence tomography of mouse ocular surface epithelial stem cells and their niche microenvironment. Investigative Ophthalmology & Visual Science 56 (12) , p. 7338. 10.1167/iovs.15-18038

Parry, Lee, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard 2015. Protocols for analyzing the role of Paneth cells in regenerating the murine intestine using conditional cre-lox mouse models. Journal of Visualized Experiments (105) , e53429. 10.3791/53429
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Piggott, Luke, Omidvar, Nader, Martí Pérez, Salvador, French, Rhiannon, Eberl, Matthias and Clarkson, Richard W. E. 2015. Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 17 (1) , p. 96. 10.1186/s13058-015-0597-9
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Reed, Karen Ruth, Athineos, Dimitris, Meniel, Valerie, Wilkins, Julie A., Ridgway, Rachel A., Burke, Zoe D., Muncan, Vanessa, Clarke, Alan Richard and Sansom, Owen J. 2015. Correction for Reed et al., B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 112 (10) , E1168. 10.1073/pnas.1502294112

Reed, Karen Ruth, Korobko, Igor, Ninkina, Natalia, Korobko, Elena V., Hopkins, Ben R., Platt, James L., Buchman, Vladimir and Clarke, Alan Richard 2015. Hunk/Mak-v is a negative regulator of intestinal cell proliferation. BMC Cancer 15 , 110. 10.1186/s12885-015-1087-2
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Siebzehnrubl, Florian 2015. Application of an RNA amplification method for reliable single-cell transcriptome analysis. Biotechniques 59 (3) , pp. 137-148. 10.2144/000114331

Soady, Kelly J., Kendrick, Howard, Gao, Qiong, Tutt, Andrew, Zvelebil, Marketa, Ordonez, Liliana, Quist, Jelmar, Tan, David Wei-Min, Isacke, Clare M., Grigoriadis, Anita and Smalley, Matthew John 2015. Mouse mammary stem cells express prognostic markers for triple-negative breast cancer. Breast Cancer Research 17 , 31. 10.1186/s13058-015-0539-6
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Tangudu, N. K., Verma, V. K., Clemons, T. D., Beevi, S. S., Hay, Trevor, Mahidhara, G., Raja, Meera, Nair, R. A., Alexander, L. E., Patel, A. B., Jose, J., Smith, N. M., Zdyrko, B., Bourdoncle, A., Luzinov, I., Iyer, K. S., Clarke, Alan Richard and Dinesh Kumar, L. 2015. RNA interference using c-Myc-conjugated nanoparticles suppresses breast and colorectal cancer models. Molecular Cancer Therapeutics 14 (5) , pp. 1259-1269. 10.1158/1535-7163.MCT-14-0970

2014

Cowley, Michael, Garfield, Alastair S., Madon-Simon, Marta, Charalambous, Marika, Clarkson, Richard W. E., Smalley, Matthew John, Kendrick, Howard, Isles, Anthony Roger, Parry, Aled J., Carney, Sara, Oakey, Rebecca J., Heisler, Lora K., Moorwood, Kim, Wolf, Jason B. and Ward, Andrew 2014. Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup. PLoS Biology 12 (2) , e1001799. 10.1371/journal.pbio.1001799
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Davies, Emma Jane, Marsh Durban, Victoria, Meniel, Valerie, Williams, Geraint Trfor and Clarke, Alan Richard 2014. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine. The Journal of Pathology 233 (1) , pp. 27-38. 10.1002/path.4312

Hickman, John A., Graeser, Ralph, de Hoogt, Ronald, Vidic, Suzana, Brito, Catarina, Gutekunst, Matthias, van der Kuip, Heiko, consortium, IMI PREDECT and Smalley, Matthew John 2014. Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo. Biotechnology Journal 9 (9) , pp. 1115-1128. 10.1002/biot.201300492

Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint Trefor, Metzger, Daniel, Shorning, Boris and Clarke, Alan Richard 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453
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Khurana, Rimpi, Verma, Vinod, Rawoof, Abdul, Tiwari, Shrish, Nair, Rekha A., Mahidhara, Ganesh, Idris, Mohammed M., Clarke, Alan Richard and Kumar, Lekha 2014. OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer. BMC Bioinformatics 15 (1) , p. 15. 10.1186/1471-2105-15-15
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Koh, D. -I., Han, D., Ryu, H., Choi, W.-I., Jeon, B. -N., Kim, M. -K., Kim, Y., Kim, J. Y., Parry, Lee, Clarke, Alan Richard, Reynolds, A. B. and Hur, M. -W. 2014. KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Proceedings of the National Academy of Sciences of the United States of America 111 (42) , pp. 15078-15083. 10.1073/pnas.1318780111

Krzystyniak, Joanna 2014. Epigenetic modulation of intestinal homeostasis and tumorigenesis by Brm SWI/SNF chromatin remodelling factor. PhD Thesis, Cardiff Univeristy.
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Marsh Durban, Victoria, Jansen, Marnix, Davies, Emma Jane, Morsink, Folkert H., Offerhaus, G. Johan A. and Clarke, Alan Richard 2014. Epithelial-specific loss of PTEN results in colorectal juvenile polyp formation and invasive cancer. American Journal of Pathology 184 (1) , pp. 86-91. 10.1016/j.ajpath.2013.10.003

Melchor, Lorenzo, Molyneux, Gemma, Mackay, Alan, Magnay, Fiona-Ann, Atienza, María, Kendrick, Howard, Nava-Rodrigues, Daniel, López-García, María Ángeles, Milanezi, Fernanda, Greenow, Kirsty Rhian, Robertson, David, Palacios, José, Reis-Filho, Jorge S. and Smalley, Matthew John 2014. Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models. The Journal of Pathology 233 (2) , pp. 124-137. 10.1002/path.4345
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Phesse, Toby, Myant, K. B., Cole, A. M., Ridgway, R. A., Pearson, Helen B., Muncan, V., van den Brink, G. R., Vousden, K. H., Sears, R., Vassilev, L . T ., Clarke, Alan Richard and Sansom, Owen J. 2014. Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo. Cell Death and Differentiation 21 , pp. 956-966. 10.1038/cdd.2014.15
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Sarkisian, Matthew R., Siebzehnrubl, Dorit, Hoang-Minh, Lan, Deleyrolle, Loic, Silver, Daniel J., Siebzehnrubl, Florian, Guadiana, Sarah M., Srivinasan, Gayathri, Semple-Rowland, Susan, Harrison, Jeffrey K., Steindler, Dennis A. and Reynolds, Brent A. 2014. Detection of primary cilia in human glioblastoma. Journal of Neuro-Oncology 117 (1) , pp. 15-24. 10.1007/s11060-013-1340-y

Suhalim, Jeffrey L., Parfitt, Geraint J, Xie, Yilu, De Paiva, Cintia S., Pflugfelder, Stephen C., Shah, Tejas N., Potma, Eric O., Brown, Donald J. and Jester, James V. 2014. Effect of desiccating stress on mouse meibomian gland function. Ocular Surface 12 (1) , pp. 59-68. 10.1016/j.jtos.2013.08.002

Tanguay, J. S., Wheeler, P., Button, M., Stevens, R., Shaw, Paul, Brewster, A., Hanna, L. and Lester, J. F. 2014. Limited stage small cell lung cancer (LS SCLC) South East Wales experience. Lung Cancer 88 (Supp 1) , S66. 10.1016/S0169-5002(14)70180-1

Tornillo, Giusy and Cabodi, Sara 2014. 3D mammary colony-forming cell assay. Bio-Protocol 4 (7)

Vedam-Mai, Vinata, Gardner, Bronwen, Okun, Michael S., Siebzehnrubl, Florian, Kam, Monica, Aponso, Palingu, Steindler, Dennis A., Yachnis, Anthony T., Neal, Dan, Oliver, Brittany U., Rath, Sean J., Faull, Richard L. M., Reynolds, Brent A. and Curtis, Maurice A. 2014. Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study. PLoS ONE 9 (3) , e88770. 10.1371/journal.pone.0088770
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2013

Colmont, Chantal Sophie, Ben Ketah, Antisar, Errington, Rachel Jane, Reed, Simon Huw, Udey, Mark C. and Patel, Girish Khandubai 2013. Human basal cell carcinoma tumor-initiating cells are resistant to etoposide [Letter]. Journal of Investigative Dermatology 134 (3) , pp. 867-870. 10.1038/jid.2013.377

Colmont, Chantal Sophie, Ben Ketah, Antisar, Reed, Simon Huw, Hawk, Nga V., Telford, William G., Ohyama, Manabu, Udeye, Mark C., Yee, Carole L., Vogel, Jonathan C. and Patel, Girish Khandubhai 2013. CD200-expressing human basal cell carcinoma cells initiate tumor growth. Proceedings of the National Academy of Sciences of the United States of America 110 (4) , pp. 1434-1439. 10.1073/pnas.1211655110

Daly, Carl S. 2013. The roles of the APC proteins in homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
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Dos Anjos Afonso, Fernando, Currie, Erin, Palmer, Hector G., Foster, Katie E., Taussig, David C. and Bonnet, Dominique 2013. CD34− cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures. Cell Stem Cell 13 (2) , pp. 161-174. 10.1016/j.stem.2013.05.025

Eccles, Suzanne A., Aboagye, Eric O., Ali, Simak, Anderson, Annie S., Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P., Brennan, Keith, Brown, Nicola J., Bryant, Helen E., Bundred, Nigel J., Burchell, Joy M., Campbell, Anna M., Carroll, Jason S., Clarke, Robert B., Coles, Charlotte E., Cook, Gary J. R., Cox, Angela, Curtin, Nicola J., Dekker, Lodewijk V., dos Santos Silva, Isabel, Duffy, Stephen W., Easton, Douglas F., Eccles, Diana M., Edwards, Dylan R., Edwards, Joanne, Evans, D. Gareth, Fenlon, Deborah F., Flanagan, James M., Foster, Claire, Gallagher, William M., Garcia-Closas, Montserrat, Gee, Julia Margaret Wendy, Gescher, Andy J., Goh, Vicky, Groves, Ashley M., Harvey, Amanda J., Harvie, Michelle, Hennessy, Bryan T., Hiscox, Stephen Edward, Holen, Ingunn, Howell, Sacha J., Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S., Jasani, Bharat, Jones, Louise J., Key, Timothy J., Kirwan, Cliona C., Kong, Anthony, Kunkler, Ian H., Langdon, Simon P., Leach, Martin O., Mann, David J., Marshall, John F., Martin, Lesley, Martin, Stewart G., Macdougall, Jennifer E., Miles, David W., Miller, William R., Morris, Joanna R., Moss, Sue M., Mullan, Paul, Natrajan, Rachel, O'Connor, James P. B., O'Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D. P., Rakha, Emad A., Reed, Elizabeth, Robinson, Simon P., Sahai, Erik, Saxton, John M., Schmid, Peter, Smalley, Matthew John, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H., Tutt, Andrew N. J., Velikova, Galina, Walker, Rosemary A., Watson, Christine J., Williams, Kaye J., Young, Leonie S. and Thompson, Alastair M. 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research 15 (5) , R92. 10.1186/bcr3493
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Greenow, Kirsty Rhian, Clarke, Alan Richard, Williams, Geraint Trefor and Jones, Robert H. 2013. Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency. Oncogene 33 , pp. 4089-4096. 10.1038/onc.2013.371

Gui, Liming and Homer, Hayden 2013. Hec1-dependent cyclin B2 stabilization regulates the G2-M transition and early prometaphase in mouse oocytes. Developmental Cell 25 (1) , pp. 43-54. 10.1016/j.devcel.2013.02.008

Hammoudi, Abeer, Song, Fei, Reed, Karen Ruth, Jenkins, Rosalind E., Meniel, Valerie, Watson, Alastair J. M., Pritchard, D. Mark, Clarke, Alan Richard and Jenkins, John R. 2013. Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC). Biochemical and Biophysical Research Communications 440 (3) , pp. 364-370. 10.1016/j.bbrc.2013.08.076

Holik, Aliaksei, Krzystyniak, Joanna, Young, Madeleine, Richardson, Kirsty, Jarde, Thierry, Chambon, Pierre, Shorning, Boris and Clarke, Alan Richard 2013. Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner. Stem Cells 31 (11) , pp. 2457-2466. 10.1002/stem.1498

Jarde, Thierry, Evans, Rebecca Jane, McQuillan, Karina, Parry, Lee, Feng, Gui Jie, Alvares, B., Clarke, Alan Richard and Dale, Trevor Clive 2013. In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system. Oncogene 32 (7) , pp. 883-893. 10.1038/onc.2012.103

Marsh Durban, Victoria, Davies, Emma Jane, Williams, Geraint Trefor and Clarke, Alan Richard 2013. PTEN loss and KRAS activation cooperate in murine biliary tract malignancies. The Journal of Pathology 230 (2) , pp. 165-173. 10.1002/path.4189

Marsh Durban, Victoria, Deuker, Marian M., Bosenberg, Marcus W., Phillips, Wayne and McMahon, Martin 2013. Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma. The Journal of Clinical Investigation 123 (12) , pp. 5104-5118. 10.1172/JCI69619

Meniel, Valerie, Song, Fei, Phesse, Toby, Young, Madeleine, Poetz, Oliver, Parry, Lee, Jenkins, John R., Williams, Geraint Trefor, Dunwoodie, Sally L., Watson, Alastair and Clarke, Alan Richard 2013. Cited1 deficiency suppresses intestinal tumorigenesis. PLoS Genetics 9 (8) , e1003638. 10.1371/journal.pgen.1003638
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Parry, Lee, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard 2013. Evidence for a crucial role of Paneth Cells in mediating the intestinal response to injury. Stem Cells 31 (4) , pp. 776-785. 10.1002/stem.1326
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Pearson, Helen B. 2013. Modelling metastasis in vivo. Madame Curie Bioscience Database, Georgetown TX: Landes Bioscience,

Pouliot, Normand, Pearson, Helen and Burrows, Allan 2013. Investigating metastasis using in vitro platforms. Madame Curie Bioscience Database, Georgetown TX: Landes Bioscience,

Raja, Meera 2013. Using GEMMs to investigate novel therapeutic strategies for colorectal cancer. PhD Thesis, Cardiff University.
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Regan, Joseph L., Sourisseau, Tony, Soady, Kelly, Kendrick, Howard, McCarthy, Afshan, Tang, Chan, Brennan, Keith, Linardopoulos, Spiros, White, Donald E. and Smalley, Matthew John 2013. Aurora A kinase regulates mammary epithelial cell fate by determining mitotic spindle orientation in a Notch-dependent manner. Cell Reports 4 (1) , pp. 110-123. 10.1016/j.celrep.2013.05.044
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Riris, Solon, Cawood, Suzanne, Gui, Liming, Serhal, Paul and Homer, Hayden A. 2013. Immunofluorescence staining of spindles, chromosomes, and kinetochores in human oocytes. In: Homer, Hayden A. ed. Mammalian Oocyte Regulation: Methods and Protocols, Methods in Molecular Biology, vol. 957. New York: Humana Press, pp. 179-187. (10.1007/978-1-62703-191-2_12)

Siebzehnrubl, Florian, Silver, Daniel J., Tugertimur, Bugra, Deleyrolle, Loic P., Siebzehnrubl, Dorit, Sarkisian, Matthew R., Devers, Kelly G., Yachnis, Antony T., Kupper, Marius D., Neal, Daniel, Nabilsi, Nancy H., Kladde, Michael P., Suslov, Oleg, Brabletz, Simone, Brabletz, Thomas, Reynolds, Brent A. and Steindler, Dennis A. 2013. The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Molecular Medicine 5 (8) , pp. 1196-1212. 10.1002/emmm.201302827

Siebzehnrubl, Florian and Steindler, Dennis A. 2013. Isolating and culturing of precursor cells from the adult human brain. Methods in Molecular Biology 1059 , pp. 79-86. 10.1007/978-1-62703-574-3_7

Silver, Daniel J., Siebzehnrubl, Florian, Schildts, Michela J., Yachnis, Anthony T., Smith, George M., Smith, Amy A., Scheffler, Bjorn, Reynolds, Brent A., Silver, Jerry and Steindler, Dennis A. 2013. Chondroitin Sulfate Proteoglycans Potently Inhibit Invasion and Serve as a Central Organizer of the Brain Tumor Microenvironment. Journal of Neuroscience 33 (39) , pp. 15603-15617. 10.1523/JNEUROSCI.3004-12.2013

Smalley, Matthew John, Piggott, Luke and Clarkson, Richard W. E. 2013. Breast cancer stem cells: obstacles to therapy. Cancer Letters 338 (1) , pp. 57-62. 10.1016/j.canlet.2012.04.023

Trejo, C. L., Green, S., Marsh Durban, Victoria, Collisson, E. A., Iezza, G., Phillips, W. A. and McMahon, M. 2013. Mutationally activated PIK3CAH1047R cooperates with BRAFV600E to promote lung cancer progression. Cancer Research 73 (21) , pp. 6448-6461. 10.1158/0008-5472.CAN-13-0681

Young, Madeleine 2013. The effects of aberrant Wnt signalling on the murine intestinal stem cell compartment. PhD Thesis, Cardiff University.
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Young, Madeleine, Ordonez, Liliana and Clarke, Alan Richard 2013. What are the best routes to effectively model human colorectal cancer? Molecular Oncology 7 (2) , pp. 178-189. 10.1016/j.molonc.2013.02.006

Zvelebil, Marketa, Oliemuller, Erik, Gao, Qiong, Wansbury, Olivia, Mackay, Alan, Kendrick, Howard, Smalley, Matthew John, Reis-Filho, Jorge S. and Howard, Beatrice A. 2013. Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers. Breast Cancer Research 15 (2) , R25. 10.1186/bcr3403
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2012

Colmont, Chantal Sophie, Harding, Keith Gordon, Piguet, Vincent and Patel, Girish Khandubhai 2012. Human skin cancer stem cells: a tale of mice and men. Experimental Dermatology 21 (8) , pp. 576-580. 10.1111/j.1600-0625.2012.01533.x

Feng, Gui Jie, Cotta, Welwyn, Wei, Xiao-Qing, Poetz, Oliver, Evans, Rebecca Jane, Jardé, Thierry, Reed, Karen Ruth, Meniel, Valerie, Williams, Geraint Trefor, Clarke, Alan Richard and Dale, Trevor Clive 2012. Conditional disruption of Axin1 leads to development of liver tumors in mice. Gastroenterology 143 (6) , pp. 1650-1659. 10.1053/j.gastro.2012.08.047

Gui, Liming and Homer, Hayden 2012. Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes. Development 139 (11) , pp. 1941-1946. 10.1242/dev.078352

Hogan, Catherine 2012. Impact of interactions between normal and transformed epithelial cells and the relevance to cancer. Cellular and Molecular Life Sciences 69 (2) , pp. 203-213. 10.1007/s00018-011-0806-3

Hopkins, S., Linderoth, E., Hantschel, O., Suarez-Henriques, P., Pilia, G., Kendrick, Howard, Smalley, Matthew John, Superti-Furga, G. and Ferby, I. 2012. Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis. Developmental Cell 23 (3) , pp. 547-559. 10.1016/j.devcel.2012.08.001
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Kallinikou, Konstantina, Dos Anjos Afonso, Fernando, Blundell, Michael P., Ings, Stuart J., Watts, Michael J., Thrasher, Adrian J., Linch, David C., Bonnet, Dominique and Yong, Kwee L. 2012. Engraftment defect of cytokine-cultured adult human mobilized CD34+ cells is related to reduced adhesion to bone marrow niche elements. British Journal of Haematology 158 (6) , pp. 778-787. 10.1111/j.1365-2141.2012.09219.x

Khritankova, I. V., Kukharskiy, M. S., Lytkina, O. A., Bachurin, S. O. and Shorning, Boris 2012. Dimebon activates autophagosome components in human neuroblastoma SH-SY5Y cells. Doklady Biochemistry and Biophysics 446 (1) , pp. 251-253. 10.1134/S1607672912050079

Milani, E. S., Brinkhaus, H., Dueggeli, R., Klebba, I., Mueller, U., Stadler, M., Kohler, H., Smalley, Matthew John and Bentires-Alj, M. 2012. Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation. Development 140 (1) , pp. 117-125. 10.1242/dev.082941

Muñoz-Descalzo, Silvia, De Navascues Melero, Joaquin and Arias, Alfonso Martinez 2012. Wnt-Notch signalling: An integrated mechanism regulating transitions between cell states. Bioessays 34 (2) , pp. 110-118. 10.1002/bies.201100102

Ordonez, Liliana and Smalley, Matthew John 2012. Who do they think they are? Wnt-responsive cells reveal their family trees. Breast Cancer Research 14 (6) , 327. 10.1186/bcr3351
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Patel, Girish Khandubhai, Yee, Carole L., Terunuma, Atsushi, Telford, William G., Voong, Nga, Yuspa, Stuart H. and Vogel, Jonathan C. 2012. Identification and characterization of tumor-initiating cells in human primary cutaneous squamous cell carcinoma. Journal of Investigative Dermatology 132 (2) , pp. 401-409. 10.1038/jid.2011.317

Patel, Girish Khandubhai, Yee, Carole L., Yuspa, Stuart H. and Vogel, Jonathan C. 2012. A humanized stromal bed is required for engraftment of isolated human primary squamous cell carcinoma cells in immunocompromised mice. Journal of Investigative Dermatology 132 (2) , pp. 284-290. 10.1038/jid.2011.284

Reed, Karen Ruth, Tunster, Simon James, Young, Madeleine, Carrico, Adam Stephen, John, Rosalind Margaret and Clarke, Alan Richard 2012. Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice. Gut 61 (10) , pp. 1435-1438. 10.1136/gutjnl-2011-300842

Shorning, Boris, Jarde, Thierry, McCarthy, Afshan, Ashworth, Alan, de Leng, Wendy W. J., Offerhaus, George Johan A., Resta, Nicoletta, Dale, Trevor Clive and Clarke, Alan Richard 2012. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1. Gut 61 (2) , pp. 202-213. 10.1136/gutjnl-2011-300046

Smalley, Matthew John, Kendrick, Howard, Sheridan, Julie M., Regan, Joseph L., Prater, Michael D., Lindeman, Geoffrey J., Watson, Christine J., Visvader, Jane E. and Stingl, John 2012. Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods. Journal of Mammary Gland Biology and Neoplasia 17 (2) , pp. 91-97. 10.1007/s10911-012-9257-1

Smartt, Helena J. M., Greenhough, Alexander, Ordonez-Moran, Paloma, Talero, Elena, Cherry, Catherine A., Wallam, Catherine A., Parry, Lee, Al Kharusi, Manal Al, Roberts, Heather R., Mariadason, John M., Clarke, Alan Richard, Huelsken, Joerg, Williams, Ann C. and Paraskeva, Chris 2012. β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells. Gut 61 (9) , pp. 1306-1314. 10.1136/gutjnl-2011-300817

Soady, Kelly and Smalley, Matthew John 2012. Slugging their way to immortality: Driving mammary epithelial cells into a stem cell-like state. Breast Cancer Research 14 (5) , 319. 10.1186/bcr3188
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Wang, Shanshan, Okun, Michael S., Suslov, Oleg, Zheng, Tong, McFarland, Nikolaus R., Vedam-Mai, Vinata, Foote, Kelly D., Roper, Steven N., Yachnis, Anthony T., Siebzehnrubl, Florian and Steindlera, Dennis A. 2012. Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains. Brain Research 1464 , pp. 61-72. 10.1016/j.brainres.2012.04.039

Williams, Rebecca, Shorning, Boris, Datta, S., Kynaston, Howard and Clarke, Alan Richard 2012. Development and characterisation of a bladder cancer model [Poster]. BJU International 109 (S7) , p. 25. 10.1111/j.1464-410X.2012.11177.x

2011

Annakesavan, Anita, Patel, Girish Khandubhai and Harding, Keith Gordon 2011. Recurrence of diffuse large B cell lymphoma presenting as a chronic non healing wound - case report [Abstract]. Wound Repair and Regeneration 19 (2) , A10. 10.1111/j.1524-475X.2010.00670.x

Bosanquet, David C., Davies, Wendy L., May, Kenneth, Harding, Keith Gordon and Patel, Girish Khandubhai 2011. Acute generalised exanthematous pustulosis following intravitreal Ranibizumab. International Wound Journal 8 (3) , pp. 317-319. 10.1111/j.1742-481X.2011.00799.x

Davies, Emma Jane, Marsh Durban, Victoria and Clarke, Alan Richard 2011. Origin and maintenance of the intestinal cancer stem cell. Molecular Carcinogenesis 50 (4) , pp. 254-263. 10.1002/mc.20631

Deleyrolle, Loic P., Harding, Angus, Cato, Kathleen, Siebzehnrubl, Florian, Rahman, Maryam, Azari, Hassan, Olson, Sarah, Gabrielli, Brian, Osborne, Geoffrey, Vescovi, Angelo and Reynolds, Brent A. 2011. Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain 134 , pp. 1331-1343. 10.1093/brain/awr081

Dos Anjos Afonso, Fernando and Bonnet, Dominique 2011. Prospective identification and isolation of murine bone marrow derived multipotent mesenchymal progenitor cells. Best Practice & Research Clinical Haematology 24 (1) , pp. 13-24. 10.1016/j.beha.2010.11.003

Hogan, Catherine, Kajita, Mihoko, Lawrenson, Kate and Fujita, Yasuyuki 2011. Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis. The International Journal of Biochemistry & Cell Biology 43 (4) , pp. 496-503. 10.1016/j.biocel.2010.12.019

Kant, P., Sainsbury, A., Reed, Karen Ruth, Pollard, S. G., Scott, N., Clarke, Alan Richard, Coletta, P. L. and Hull, M. A. 2011. Rectal epithelial cell mitosis and expression of macrophage migration inhibitory factor are increased 3 years after Roux-en-Y gastric bypass (RYGB) for morbid obesity: implications for long-term neoplastic risk following RYGB. Gut 60 (7) , pp. 893-901. 10.1136/gut.2010.230755

Matthews, James, Sansom, O. J. and Clarke, Alan Richard 2011. Absolute requirement for STAT3 function in small-intestine crypt stem cell survival. Cell Death and Differentiation 18 (12) , pp. 1934-1943. 10.1038/cdd.2011.77

Miyamoto, T., Porazinski, Sean, Wang, H., Borovina, A., Ciruna, B., Shimizu, A., Kajii, T., Kikuchi, A., Furutani-Seiki, M. and Matsuura, S. 2011. Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates. Human Molecular Genetics 20 (10) , pp. 2058-2070. 10.1093/hmg/ddr090

Parry, Lee and Clarke, Alan Richard 2011. The roles of the methyl-CpG binding proteins in cancer. Genes & Cancer 2 (6) , pp. 618-630. 10.1177/1947601911418499

Piggott, Luke, Omidvar, Nader, Marti-Perez, Salvador, Eberl, Matthias and Clarkson, Richard W. E. 2011. Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 13 (5) , R88. 10.1186/bcr2945
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Porazinski, Sean, Wang, Huijia and Furutani-Seiki, Makoto 2011. Essential techniques for introducing medaka to a zebrafish laboratory-towards the combined use of medaka and zebrafish for further genetic dissection of the function of the vertebrate genome. Methods in Molecular Biology 770 , pp. 211-241. 10.1007/978-1-61779-210-6_8

Richards, Alastair J., Hagelstein, Susan M., Patel, Girish Khandubhai, Ivins, Nicola M., Sweetland, Helen Margaret and Harding, Keith Gordon 2011. Early use of negative pressure therapy in combination with silver dressings in a difficult breast abscess. International Wound Journal 8 (6) , pp. 608-611. 10.1111/j.1742-481X.2011.00838.x

Sanders, Andrew James, Jiang, David G., Jiang, Wen Guo, Harding, Keith Gordon and Patel, Girish Khandubhai 2011. Activated leukocyte cell adhesion molecule impacts on clinical wound healing and inhibits HaCaT migration. International Wound Journal 8 (5) , pp. 500-507. 10.1111/j.1742-481X.2011.00823.x

Shorning, Boris and Clarke, Alan Richard 2011. LKB1 loss of function studied in vivo. FEBS Letters 585 (7) , pp. 958-966. 10.1016/j.febslet.2011.01.019

Shorning, Boris, Griffiths, David Francis Rees and Clarke, Alan Richard 2011. Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder. PLoS ONE 6 (1) , e16209. 10.1371/journal.pone.0016209
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Siebzehnrubl, Florian, Reynolds, B. A., Vescovi, A., Steindler, D. A. and Deleyrolle, L. P. 2011. The origins of glioma: E pluribus unum? GLIA 59 (8) , pp. 1135-1147. 10.1002/glia.21143

Siebzehnrubl, Florian, Vedam-Mai, Vinata, Azari, Hassan, Reynolds, Brent A. and Deleyrolle, Loic P. 2011. Isolation and characterization of adult neural stem cells. Methods in Molecular Biology 750 , pp. 61-77. 10.1007/978-1-61779-145-1_4

Steffenhagen, Carolin, Kraus, Sabrina, Dechant, Franz-Xaver, Kandasamy, Mahesh, Lehner, Bernadette, Poehler, Anne-Maria, Furtner, Tanja, Siebzehnrubl, Florian, Couillard-Despres, Sebastien, Strauss, Olaf, Aigner, Ludwig and Rivera, Francisco J. 2011. Identity, fate and potential of cells grown as neurospheres: species matters. Stem Cell Reviews and Reports 7 (4) , pp. 815-835. 10.1007/s12015-011-9251-9

Thomas, Rhian Sara, Clarke, Alan Richard, Duance, Victor Colin and Blain, Emma Jane 2011. Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis. Arthritis Research and Therapy 13 (6) , R203. 10.1186/ar3536
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Vargaftig, J., Taussig, D. C., Griessinger, E., Dos Anjos Afonso, Fernando, Lister, T. A., Cavenagh, J., Oakervee, H., Gribben, J. and Bonnet, Dominique 2011. Frequency of leukemic initiating cells does not depend on the xenotransplantation model used. Leukemia 26 (4) , pp. 858-860. 10.1038/leu.2011.250

Young, Madeleine and Clarke, Alan Richard 2011. Expanding the p53 toolkit: A new platform for rapid engineering of the p53 locus in vivo [Note]. Cell Cycle 10 (14) , p. 2249. 10.4161/cc.10.14.16205

2010

Ashton, Gabrielle H., Morton, Jennifer P., Myant, Kevin, Phesse, Toby, Ridgway, Rachel A., Marsh Durban, Victoria, Wilkins, Julie A., Athineos, Dimitris, Muncan, Vanesa, Kemp, Richard, Neufeld, Kristi, Clevers, Hans, Brunton, Valerie, Winton, Douglas J., Wang, Xiaoyan, Sears, Rosalie C., Clarke, Alan Richard, Frame, Margaret C. and Sansom, Owen J. 2010. Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling. Developmental Cell 19 (2) , pp. 259-269. 10.1016/j.devcel.2010.07.015

Buchert, Michael, Athineos, Dimitris, Abud, Helen E., Burke, Zoe D., Faux, Maree C., Samuel, Michael S., Jarnicki, Andrew G., Winbanks, Catherine E., Newton, Ian P, Meniel, Valerie, Suzuki, Hiromu, Stacker, Steven A., Näthke, Inke S., Tosh, David, Huelsken, Joerg, Clarke, Alan Richard, Heath, Joan K., Sansom, Owen J. and Ernst, Matthias 2010. Genetic dissection of differential signaling threshold requirements for the Wnt/beta-Catenin pathway in vivo. PLOS Genetics 6 (1) , e1000816. 10.1371/journal.pgen.1000816
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Cole, Alicia, Ridgway, Rachel, Derkits, Sahra, Parry, Lee, Barker, Nick, Clevers, Hans, Clarke, Alan Richard and Sansom, Owen 2010. p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium. EMBO Molecular Medicine 2 (11) , pp. 472-486. 10.1002/emmm.201000101

Cole, Alicia M., Myant, Kevin, Reed, Karen Ruth, Ridgway, Rachel A., Athineos, Dimitris, Van den Brink, Gijs, Muncan, Vanesa, Clevers, Hans, Clarke, Alan Richard, Sicinski, Peter and Sansom, Owen J. 2010. Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss. Cancer Research 70 (20) , pp. 8149-8158. 10.1158/0008-5472.CAN-10-0315

Coras, Roland, Siebzehnrubl, Florian, Pauli, Elisabeth, Huttner, Hagen B., Njunting, Marleisje, Kobow, Katja, Villmann, Carmen, Hahnen, Eric, Neuhuber, Winfried, Weigel, Daniel, Buchfelder, Michael, Stefan, Hermann, Beck, Heinz, Steindler, Dennis A. and Bluemcke, Ingmar 2010. Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain 133 (11) , pp. 3359-3372. 10.1093/brain/awq215

De Navascues Melero, Joaquin and Modolell, Juan 2010. The pronotum LIM-HD gene tailup is both a positive and a negative regulator of the proneural genes achaete and scute of Drosophila. Mechanisms of Development 127 (9-12) , pp. 393-406. 10.1016/j.mod.2010.05.001

Ghafoor, Sana Z. A., MacRae, Eva A., Harding, Keith Gordon and Patel, Girish Khandubhai 2010. Symmetrical peripheral digital gangrene following severe Plasmodium falciparum malaria-induced disseminated intravascular coagulopathy. International Wound Journal 7 (5) , pp. 418-422. 10.1111/j.1742-481X.2010.00697.x

Jiang, Wen Guo, Ye, Lin, Patel, Girish Khandubhai and Harding, Keith Gordon 2010. Expression of WAVEs, the WASP (Wiskott-Aldrich syndrome protein) family of verprolin homologous proteins in human wound tissues and the biological influence on human keratinocytes. Wound Repair and Regeneration 18 (6) , pp. 594-604. 10.1111/j.1524-475X.2010.00630.x

Kajita, Mihoko, Hogan, Catherine, Harris, Andrew R., Dupre-Crochet, Sophie, Itasaki, Nobue, Kawakami, Koichi, Charras, Guillaume, Tada, Masazumi and Fujita, Yasuyuki 2010. Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells. Journal of Cell Science 123 (2) , pp. 171-180. 10.1242/jcs.057976

Minhas, Uzma, Sanders, Andrew James, Patel, Girish Khandubhai, Harding, Keith Gordon and Jiang, Wen Guo 2010. Activated leukocyte cell adhesion molecule (ALCAM) - biological impact on vascular endothelial cells [Abstract]. Wound Repair and Regeneration 18 (6) , A89. 10.1111/j.1524-475X.2010.00633.x

Patel, Girish Khandubhai, Davies, Wendy L., Price, Patricia Elaine and Harding, Keith Gordon 2010. Ulcerated tophaceous gout. International Wound Journal 7 (5) , pp. 423-427. 10.1111/j.1742-481X.2010.00700.x

Patel, Girish Khandubhai and Harding, Keith Gordon 2010. Nicorandil ulcer: moves beyond the mucosa. Annals of the Royal College of Surgeons of England 92 (6) , pp. 451-452. 10.1308/003588410X12699663905195

Porazinski, Sean, Wang, Huijia and Furutani-Seiki, Makoto 2010. Microinjection of medaka embryos for use as a model genetic organism. Journal of Visualized Experiments (46) , e1937. 10.3791/1937

Poulin, L. F., Salio, M., Griessinger, E., Dos Anjos Afonso, Fernando, Craciun, L., Chen, J. -L., Keller, A. M., Joffre, O., Zelenay, S., Nye, E., Le Moine, A., Faure, F., Donckier, V., Sancho, D., Cerundolo, V., Bonnet, Dominique and Reis e Sousa, C. 2010. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8 + dendritic cells. Journal of Experimental Medicine 207 (6) , pp. 1261-1271. 10.1084/jem.20092618

Rangaraj, Aravindan, Ye, Lin, Patel, Girish Khandubhai, Harding, Keith Gordon and Jiang, Wen Guo 2010. The role of Bik1 (BCL-2 interaction killer) in wound healing [Abstract]. Wound Repair and Regeneration 18 (6) , A92. 10.1111/j.1524-475X.2010.00633.x

Rangaraj, Aravindan, Ye, Lin, Patel, Girish Khandubhai, Price, Patricia Elaine, Harding, Keith Gordon and Jiang, Wen Guo 2010. The molecular and cellular roles of Psoriasin (S100A4) in human cutaneous wound healing [Abstract]. Wound Repair and Regeneration 18 (6) , A92. 10.1111/j.1524-475X.2010.00633.x

van Dop, Willemijn, Heijmans, Jarom, Büller, Nikè, Snoek, Susanne, Rosekrans, Sanne, Wassenberg, Elisabeth, van den Bergh Weerman, Marius, Lanske, Beate, Clarke, Alan Richard, Winton, Douglas, Wijgerde, Mark, Offerhaus, G. Johan, Hommes, Daan, Hardwick, James, de Jonge, Wouter, Biemond, Izak and van den Brink, Gijs 2010. Loss of Indian hedgehog activates multiple aspects of a wound healing response in the mouse intestine. Gastroenterology 139 (5) , pp. 1665-1676. 10.1053/j.gastro.2010.07.045

2009

Alexander, Caroline M., Puchalski, Joel, Klos, Kristine S., Badders, Nisha, Ailles, Laurie, Kim, Carla F., Dirks, Peter and Smalley, Matthew John 2009. Separating stem cells by flow cytometry: reducing variability for solid tissues. Cell Stem Cell 5 (6) , pp. 579-583. 10.1016/j.stem.2009.11.008

Barker, Nick, Ridgway, Rachel A., Van Es, Johan H., Van De Wetering, Marc, Begthel, Harry, Van Den Born, Maaike, Danenberg, Esther, Clarke, Alan Richard, Sansom, Owen J. and Clevers, Hans 2009. Crypt stem cells as the cells-of-origin of intestinal cancer [Letter]. Nature 457 (7229) , pp. 608-611. 10.1038/nature07602

Burke, Zoé D., Reed, Karen Ruth, Phesse, Toby, Sansom, Owen J., Clarke, Alan Richard and Tosh, David 2009. Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism. Gastroenterology 136 (7) , pp. 2316-2324. 10.1053/j.gastro.2009.02.063

Greenow, Kirsty Rhian, Clarke, Alan Richard and Jones, Robert H. 2009. Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation. Oncogene 28 (11) , pp. 1443-1453. 10.1038/onc.2008.482

Hogan, Catherine, Dupré-Crochet, Sophie, Norman, Mark, Kajita, Mihoko, Zimmermann, Carola, Pelling, Andrew E., Piddini, Eugenia, Baena-López, Luis Alberto, Vincent, Jean-Paul, Itoh, Yoshifumi, Hosoya, Hiroshi, Pichaud, Franck and Fujita, Yasuyuki 2009. Characterization of the interface between normal and transformed epithelial cells [Letter]. Nature Cell Biology 11 (4) , pp. 460-467. 10.1038/ncb1853

Homer, Hayden, Gui, Liming and Carroll, John 2009. A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression. Science 326 (5955) , pp. 991-994. 10.1126/science.1175326

Phesse, Toby and Clarke, Alan Richard 2009. Normal stem cells in cancer prone epithelial tissues. British Journal of Cancer 100 (2) , pp. 221-227. 10.1038/sj.bjc.6604850

Rivera, Francisco J., Siebzehnrubl, Florian, Kandasamy, Mahesh, Couillard-Despres, Sebastien, Caioni, Massimiliano, Poehler, Anne-Maria, Berninger, Benedikt, Sandner, Beatrice, Bogdahn, Ulrich, Goetz, Magdalena, Bluemcke, Ingmar, Weidner, Norbert and Aigner, Ludwig 2009. Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures. Cellular Physiology and Biochemistry 24 (3-4) , pp. 317-324. 10.1159/000233256

Ruzov, Alexey, Shorning, Boris, Mortusewicz, Oliver, Dunican, Donncha S., Leonhardt, Heinrich and Meehan, Richard R. 2009. MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development 136 (13) , pp. 2277-2286. 10.1242/dev.032227

Shorning, Boris, Zabkiewicz, Joanna, McCarthy, Afshan, Pearson, Helen B., Winton, Douglas J., Sansom, Owen J., Ashworth, Alam and Clarke, Alan Richard 2009. Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine. PLoS ONE 4 (1) , e4264. 10.1371/journal.pone.0004264
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Siebzehnrubl, Florian, Jeske, Ina, Mueller, Dorit, Buslei, Rolf, Coras, Roland, Hahnen, Eric, Huttner, Hagen B., Corbeil, Denis, Kaesbauer, Johanna, Appl, Thomas, von Hoersten, Stephan and Bluemcke, Ingmar 2009. Spontaneous in vitro transformation of adult neural precursors into stem-like cancer cells. Brain Pathology 19 (3) , pp. 399-408. 10.1111/j.1750-3639.2008.00189.x

Smith, Paul James, Furon, Emeline, Wiltshire, Marie, Campbell, Lee, Feeney, Graham P., Snyder, R. D. and Errington, Rachel Jane 2009. ABCG2-Associated Resistance to Hoechst 33342 and Topotecan in a Murine Cell Model with Constitutive Expression of Side Population Characteristics. Cytometry Part A 75A (11) , pp. 924-933. 10.1002/cyto.a.20800

Weiss, S., Siebzehnrubl, Florian, Kreutzer, J., Bluemcke, I. and Buslei, R. 2009. Evidence for a progenitor cell population in the human pituitary. Clinical Neuropathology 28 (4) , pp. 309-318.

2008

Dos Anjos Afonso, Fernando and Bonnet, Dominique 2008. Isolation, culture, and differentiation potential of mouse marrow stromal cells. Current Protocols in Stem Cell Biology 10.1002/9780470151808.sc02b03s7

Huttner, Hagen B., Janich, Peggy, Koehrmann, Martin, Jaszai, Jozsef, Siebzehnrubl, Florian, Bluemcke, Ingmar, Suttorp, Meinolf, Gahr, Manfred, Kuhnt, Daniela, Nimsky, Christopher, Krex, Dietmar, Schackert, Gabriele, Loewenbrueck, Kai, Reichmann, Heinz, Juettler, Eric, Hacke, Werner, Schellinger, Peter D., Schwab, Stefan, Wilsch-Braeuninger, Michaela, Marzesco, Anne-Marie and Corbeil, Denis 2008. The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease. Stem Cells 26 (3) , pp. 698-705. 10.1634/stemcells.2007-0639

Marsh Durban, Victoria, Winton, Douglas J., Williams, Geraint Trefor, Dubois, Nicole, Trumpp, Andreas, Sansom, Owen J. and Clarke, Alan Richard 2008. Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation. Nature Genetics 40 (12) , pp. 1436-1444. 10.1038/ng.256

Pálmer, Héctor G., Dos Anjos Afonso, Fernando, Carmeliet, Geert, Takeda, Hikaru and Watt, Fiona M. 2008. The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS ONE 3 (1) , e1483. 10.1371/journal.pone.0001483
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Phesse, Toby, Parry, Lee, Reed, Karen Ruth, Ewan, Kenneth Burnside Ramsay, Dale, Trevor Clive, Sansom, Owen J. and Clarke, Alan Richard 2008. Deficiency of Mbd2 attenuates Wnt induced tumourigenesis via deregulation of a novel Wnt inhibitor, Lect.2. Molecular and Cellular Biology 28 (19) , pp. 6094-6103. 10.1128/MCB.00539-08

Reed, Karen Ruth, Athineos, Dimitris, Meniel, Valerie, Wilkins, Julie Ann, Ridgeway, Rachel A., Burke, Zoe D., Muncan, Vanesa, Clarke, Alan Richard and Sansom, Owen J. 2008. B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 105 (48) , pp. 18919-18923. 10.1073/pnas.0805778105

Reed, Karen Ruth, Meniel, Valerie, Marsh Durban, Victoria, Cole, Alicia, Sansom, Owen J. and Clarke, Alan Richard 2008. A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine. BMC Cancer 8 , 162. 10.1186/1471-2407-8-162
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Siebzehnrubl, Florian and Blumcke, Ingmar 2008. Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies. Epilepsia 49 (s5) , pp. 55-65. 10.1111/j.1528-1167.2008.01638.x

Taussig, D. C., Miraki-Moud, F., Dos Anjos Afonso, Fernando, Pearce, D. J., Allen, K., Ridler, C., Lillington, D., Oakervee, H., Cavenagh, J., Agrawal, S. G., Lister, T. A., Gribben, J. G. and Bonnet, Dominique 2008. Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells. Blood -New York- 112 (3) , pp. 568-575. 10.1182/blood-2007-10-118331

2007

Britt, K., Ashworth, A. and Smalley, Matthew John 2007. Pregnancy and the risk of breast cancer. Endocrine-Related Cancer 14 (4) , pp. 907-933. 10.1677/ERC-07-0137

Buslei, Rolf, Hoelsken, Annett, Hofmann, Bernd, Kreutzer, Juergen, Siebzehnrubl, Florian, Hans, Volkmar, Oppel, Falk, Buchfelder, Michael, Fahlbusch, Rudolf and Bluemcke, Ingmar 2007. Nuclear beta-catenin accumulation associates with epithelial morphogenesis in craniopharyngiomas. Acta Neuropathologica 113 (5) , pp. 585-590.

Clarke, Alan Richard and Meniel, Valerie 2007. The intestinal stem cell niche studied through conditional transgenesis. Presented at: The Cancer Stem Cell Workshop, Berlin, Germany, November 15- 17 2006. Published in: Wiestler, O. D., Haendler, B. and Mumberg, D. eds. Cancer Stem Cells: Novel Concepts and Prospects for Tumor Therapy. Ernst Schering Foundation Symposium Proceedings Berlin: Springer, pp. 99-108. 10.1007/2789_2007_046

Coras, Roland, Hoelsken, Annett, Seufert, Sebastian, Hauke, Jan, Eyuepoglu, Ilker Y., Reichel, Martin, Traenkle, Christian, Siebzehnrubl, Florian, Buslei, Rolf, Bluemcke, Ingmar and Hahnen, Eric 2007. The peroxisome proliferator-activated receptor-gamma agonist troglitazone inhibits transforming growth factor-beta-mediated glioma cell migration and brain invasion. Molecular Cancer Therapeutics 6 (6) , pp. 1745-1754. 10.1158/1535-7163.MCT-06-0763

De Navascues Melero, Joaquin and Modolell, J. 2007. tailup, a LIM-HD gene, and Iro-C cooperate in Drosophila dorsal mesothorax specification. Development 134 (9) , pp. 1779-1788. 10.1242/dev.02844

Dikovskaya, Dina, Schiffmann, David, Newton, Ian P., Oakley, Abigail, Kroboth, Karin, Sansom, Owen J., Jamieson, Thomas J., Meniel, Valerie, Clarke, Alan Richard and Nathke, Inke S. 2007. Correction 176, p. 183. Journal of cell biology 176 (3) , p. 369. 10.1083/jcb.20061009920070116c

Dikovskaya, Dina, Schiffmann, David, Newton, Ian P., Oakley, Abigail, Kroboth, Karin, Sansom, Owen J., Jamieson, Thomas J., Meniel, Valerie, Clarke, Alan Richard and Nathke, Inke S. 2007. Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. Journal of cell biology 176 (2) , pp. 183-195. 10.1083/jcb.200610099

Dos Anjos Afonso, Fernando and Bonnet, Dominique 2007. Flexible and dynamic organization of bone marrow stromal compartment. British Journal of Haematology 139 (3) , pp. 373-384. 10.1111/j.1365-2141.2007.06827.x

Dupre-Crochet, S., Figueroa, A., Hogan, Catherine, Ferber, E. C., Bialucha, C. U., Adams, J., Richardson, E. C. N. and Fujita, Y. 2007. Casein Kinase 1 Is a novel negative regulator of E-cadherin-based cell-cell contacts. Molecular and Cellular Biology 27 (10) , pp. 3804-3816. 10.1128/MCB.01590-06

Hosking, C. R., Ulloa, F., Hogan, Catherine, Ferber, E. C., Figueroa, A., Gevaert, K., Birchmeier, W., Briscoe, J. and Fujita, Y. 2007. The transcriptional repressor Glis2 Is a novel binding partner for p120 catenin. Molecular biology of the cell 18 (5) , pp. 1918-1927. 10.1091/mbc.E06-10-0941

Marsh Durban, Victoria and Clarke, Alan Richard 2007. Intestinal homeostasis and neoplasia studied using conditional transgenesis. Expert Review of Anticancer Therapy 7 (4) , pp. 519-531. 10.1586/14737140.7.4.519

Matthews, James, Watson, Susan M. R., Tevendale, Maxine C. L., Watson, Christine J. and Clarke, Alan Richard 2007. Caspase-dependent proteolytic cleavage of STAT3a in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines. BMC Cancer 7 (29) , pp. 1-12. 10.1186/1471-2407-7-29
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Nijnik, Anastasia, Woodbine, Lisa, Marchetti, Caterina, Dawson, Sara, Lambe, Teresa, Liu, Cong, Rodrigues, Neil, Crockford, Tanya L., Cabuy, Erik, Vindigni, Alessandro, Enver, Tariq, Bell, John I., Slijepcevic, Predrag, Goodnow, Christopher C., Jeggo, Penelope A. and Cornall, Richard J. 2007. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447 (7145) , pp. 686-690. 10.1038/nature05875

Pearce, Daniel J., Dos Anjos Afonso, Fernando, Ridler, Christopher M., Eddaoudi, Ayad and Bonnet, Dominique 2007. Age-dependent increase in side population distribution within hematopoiesis: Implications for our understanding of the mechanism of aging. Stem Cells 25 (4) , pp. 828-835. 10.1634/stemcells.2006-0405

Pearce, Daniel J., Dos Anjos-Afonso, Fernando, Ridler, Christopher M., Eddaoudi, Ayad and Bonnet, Dominique 2007. Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging. Stem Cells 25 (7) , p. 1852. 10.1634/stemcells.2006-0405erratum

Regan, Joseph and Smalley, Matthew John 2007. Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland. Stem Cell Reviews 3 (2) , pp. 124-136. 10.1007/s12015-007-0017-3

Sansom, Owen J., Meniel, Valerie, Muncan, Vanesa, Phesse, Toby, Wilkins, Julie Ann, Reed, Karen Ruth, Vass, Keith, Athineos, Dimitris, Clevers, Hans and Clarke, Alan Richard 2007. Myc deletion rescues Apc deficiency in the small intestine. Nature 446 (7136) , pp. 676-679. 10.1038/nature05674

Shaw, Paul and Clarke, Alan Richard 2007. Murine models of intestinal cancer: Recent advances. DNA Repair 6 (10) , pp. 1403-1412. 10.1016/j.dnarep.2007.02.022

Siebzehnrubl, Florian, Buslei, Rolf, Eyupoglu, Ilker Y., Seufert, Sebastian, Hahnen, Eric and Blumcke, Ingmar 2007. Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells. Experimental Brain Research 176 (4) , pp. 672-678. 10.1007/s00221-006-0831-x

Sleeman, K. E., Kendrick, H., Robertson, D., Isacke, C. M., Ashworth, A. and Smalley, Matthew John 2007. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. Journal of cell biology 176 (1) , pp. 19-26. 10.1083/jcb.200604065

Smalley, Matthew John, Iravani, M., Leao, M., Grigoriadis, A., Kendrick, Howard, Dexter, T., Fenwick, K., Regan, J. L., Britt, K., McDonald, S., Lord, C. J., Mackay, A. and Ashworth, A. 2007. Regulator of G-protein signalling 2 (RGS2) mRNA is differentially expressed in mammary epithelial subpopulations and overexpressed in the majority of breast cancers. Breast Cancer Research 9 (6) , R85. 10.1186/bcr1834

2006

Buslei, R., Kreutzer, J., Hofmann, B., Schmidt, V., Siebzehnrubl, Florian, Hahnen, E., Eyupoglu, I. Y., Fahlbusch, R. and Blumcke, I. 2006. Abundant hypermethylation of SOCS-1 in clinically silent pituitary adenomas. Acta Neuropathologica 111 (3) , pp. 264-271. 10.1007/s00401-005-0009-9

Dos Anjos Afonso, Fernando and Bonnet, Dominique 2006. Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment. Blood 109 (3) , pp. 1298-1306. 10.1182/blood-2006-06-030551

Eyupoglu, I. Y., Hahnen, E., Tränkle, C., Savaskan, N. E., Siebzehnrubl, Florian, Buslei, R., Lemke, D., Wick, W., Fahlbusch, R. and Blümcke, I. 2006. Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275. Molecular Cancer Therapeutics 5 (5) , p. 1248. 10.1158/1535-7163.MCT-05-0533

Fujita, Yasuyuki, Hogan, Catherine and Braga, Vania M. M. 2006. Regulation of cell–cell adhesion by Rap1. Methods in Enzymology 407 , pp. 359-372. 10.1016/S0076-6879(05)07030-8

Hahnen, E., Eyupoglu, I. Y., Brichta, L., Haastert, K., Trankle, C., Siebzehnrubl, Florian, Riessland, M., Holker, I., Claus, P., Romstock, J., Buslei, R., Wirth, B. and Blumcke, I. 2006. In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy. Journal of Neurochemistry 98 (1) , pp. 193-202. 10.1111/j.1471-4159.2006.03868.x

Hay, T., Jenkins, H., Sansom, O. J., Martin, N. M. B., Smith, G. C. M. and Clarke, Alan Richard 2006. Brca2 deficiency sensitizes cells to PARP inhibition [Correction to Hay et al. 65 (22): 10145]. Cancer Research 66 (1) , p. 599. 10.1158/0008-5472.CAN-66-1-COR

Hoelsken, Annett, Eyuepoglu, Ilker Y., Lueders, Mike, Traenkle, Christian, Dieckmann, Detlef, Buslei, Rolf, Hahnen, Eric, Bluemcke, Ingmar and Siebzehnrubl, Florian 2006. Ex vivo therapy of malignant melanomas transplanted into organotypic brain slice cultures using inhibitors of histone deacetylases. Acta Neuropathologica 112 (2) , pp. 205-215. 10.1007/s00401-006-0082-8

Patel, Girish Khandubhai, Goodwin, Richard, Chawla, Maureen, Laidler, Peter, Price, Patricia Elaine, Finlay, Andrew Yule and Motley, Richard J. 2006. Imiquimod 5% cream monotherapy for cutaneous squamous cell carcinoma in situ (Bowen's disease): a randomized, double-blind, placebo-controlled trial. Journal of the American Academy of Dermatology 54 (6) , pp. 1025-1032. 10.1016/j.jaad.2006.01.055

Reed, Karen Ruth, Sansom, Owen J., Hayes, Anthony Joseph, Gescher, Andreas J., Peters, Jefferey M. and Clarke, Alan Richard 2006. PPARδ status and mismatch repair mediated neoplasia in the mouse intestine. BMC Cancer 6 (113) 10.1186/1471-2407-6-113
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Sansom, Owen J., Meniel, Valerie, Wilkins, Julie Ann, Cole, Alicia M., Oien, Karin A., Marsh Durban, Victoria, Jamieson, Thomas J., Guerra, Carmen, Ashton, Gabrielle H., Barbacid, Mariano and Clarke, Alan Richard 2006. Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo. Proceedings of the National Academy of Sciences 103 (38) , pp. 14122-14127. 10.1073/pnas.0604130103

Sleeman, Katherine E., Kendrick, Howard, Ashworth, Alan, Isacke, Clare M. and Smalley, Matthew John 2006. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Research 8 (R7) 10.1186/bcr1371

Tu, Zheng, Gui, Liming, Wang, Jianliu, Li, Xiaoping, Sun, Pengming and Wei, Lihui 2006. Tumorigenesis of K-ras mutation in human endometrial carcinoma via upregulation of estrogen receptor. Gynecologic Oncology 101 (2) , pp. 274-279. 10.1016/j.ygyno.2005.10.016

2005

Buslei, R., Nolde, M., Hofmann, B., Meissner, S., Eyupoglu, I. Y., Siebzehnrubl, Florian, Hahnen, E., Kreutzer, J. and Fahlbusch, R. 2005. Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region. Acta Neuropathologica 109 (6) , pp. 589-597.

Craiu, A., Saito, Y., Limon, A., Eppich, H. M., Olson, D. P., Rodrigues, Neil, Adams, G. B., Dombkowski, D., Richardson, P., Schlossman, R., Choi, P. S., Grogins, J., O'Connor, P. G., Cohen, K., Attar, E. C., Freshman, J., Rich, R., Mangano, J. A., Gribben, J. G., Anderson, K. C. and Scadden, D. T. 2005. Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood 105 (5) , pp. 2235-2238. 10.1182/blood-2003-12-4399

Eyupoglu, I. Y., Hahnen, E., Buslei, R., Siebzehnrubl, Florian, Savaskan, N. E., Luders, M., Trankle, C., Wick, W., Weller, M., Fahlbusch, R. and Blumcke, I. 2005. Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo. Journal of Neurochemistry 93 (4) , pp. 992-999. 10.1111/j.1471-4159.2005.03098.x

Eyupoglu, I. Y., Hahnen, E., Heckel, A., Siebzehnrubl, Florian, Buslei, R., Fahlbusch, R. and Blumcke, I. 2005. Malignant glioma-induced neuronal cell death in an organotypic glioma invasion model. Technical note. Journal of Neurosurgery 102 (4) , pp. 738-744. 10.3171/jns.2005.102.4.0738

Meniel, Valerie, Hay, Trevor, Douglas-Jones, Anthony Gordon, Sansom, Owen J. and Clarke, Alan R. 2005. Mutations in Apc and p53 synergize to promote mammary neoplasia. Cancer Research 65 (24) , pp. 410-6.

Rodrigues, Neil, Janzen, V., Forkert, R., Dombkowski, D. M., Boyd, A. S., Orkin, S. H., Enver, T., Vyas, P. and Scadden, D. 2005. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis. Blood 106 (2) , pp. 477-484. 10.1182/blood-2004-08-2989

Sansom, Owen J., Griffiths, David Francis Rees, Reed, Karen Ruth, Winton, Douglas J. and Clarke, Alan Richard 2005. Apc deficiency predisposes to renal carcinoma in the mouse. Oncogene 24 , pp. 8205-8210. 10.1038/sj.onc.1208956

Sansom, Owen J., Reed, Karen Ruth, van de Wetering, M., Muncan, V., Winton, D. J., Clevers, H. and Clarke, Alan Richard 2005. Cyclin D1 is not an immediate target of β-Catenin following Apc loss in the intestine. Journal of Biological Chemistry 280 (31) , pp. 28463-28467. 10.1074/jbc.M500191200

Smalley, Matthew John and Clarke, Robert B. 2005. The mammary gland “side population”: a putative stem/progenitor cell marker? Journal of Mammary Gland Biology and Neoplasia 10 (1) , pp. 37-47. 10.1007/s10911-005-2539-0

Smalley, Matthew John, Titley, I. and Ashworth, A. 2005. An improved definition of mouse mammary epithelial side population cells. Cytotherapy 7 (6) , pp. 497-508. 10.1080/14653240500361145

Wilson, Catherine Helen, Idziaszczyk, Shelley Alexis, Parry, Lee, Guy, Carol, Griffiths, David Francis Rees, Lazda, Edgar Janis, Bayne, Rosemary A. L., Smith, Andrew J. H., Sampson, Julian Roy and Cheadle, Jeremy Peter 2005. A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma. Human Molecular Genetics 14 (13) , pp. 1839-1850. 10.1093/hmg/ddi190

2004

Clarkson, Richard W. E., Wayland, M. T., Lee, J., Freeman, T. and Watson, C. J. 2004. Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression. Breast Cancer Research 6 (2) , R92-R109.
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Dos Anjos Afonso, Fernando, Siapati, Elena K. and Bonnet, Dominique 2004. In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions. Journal of Cell Science 117 (23) , pp. 5655-5664. 10.1242/jcs.01488

Hogan, Catherine, Serpente, N., Cogram, P., Hosking, C. R., Bialucha, C. U., Feller, S. M., Braga, V. M. M., Birchmeier, W. and Fujita, Y. 2004. Rap1 regulates the formation of E-Cadherin-based cell-cell contacts. Molecular and Cellular Biology 24 (15) , pp. 6690-6700. 10.1128/MCB.24.15.6690-6700.2004

Kirby, Denise M., Salemi, Renato, Sugiana, Canny, Ohtake, Akira, Parry, Lee, Bell, Katrina M., Kirk, Edwin P., Boneh, Avihu, Taylor, Robert W., Dahl, Hans-Henrik M., Ryan, Michael T. and Thorburn, David R. 2004. NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency. The Journal of Clinical Investigation 114 (6) , pp. 837-845. 10.1172/JCI200420683
file

Milligan, G., Feng, Gui Jie, Ward, R., Sartania, N., Ramsay, D., McLean, A. and Carrillo, J. 2004. G protein-coupled receptor fusion proteins in drug discovery. Current Pharmaceutical Design 10 (17) , pp. 1989-2001. 10.2174/1381612043384295

Murdoch, H., Feng, Gui Jie, Bachner, D., Ormiston, L., White, J. H., Richter, D. and Milligan, G. 2004. Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail. Journal of Biological Chemistry 280 (9) , pp. 8208-8220. 10.1074/jbc.M405215200

Murdoch, H., Milligan, G., Kellett, E., White, J. H. and Feng, Gui Jie 2004. Interactions between G-protein-coupled receptors and periplakin: a selective means to regulate G-protein activation. Biochemical Society Transactions 32 (5) , pp. 878-880. 10.1042/BST0320878

Qiu, J., Takagi, Y., Harada, J., Rodrigues, Neil, Moskowitz, M. A., Scadden, D. T. and Cheng, T. 2004. Regenerative response in ischemic brain restricted by p21cip1/waf1. Journal of Experimental Medicine 199 (7) , pp. 937-945. 10.1084/jem.20031385

Reed, Karen Ruth, Sansom, Owen J., Hayes, Anthony Joseph, Gescher, Andreas J., Winton, Douglas J., Peters, Jeffrey M. and Clarke, Alan Richard 2004. PPARδ status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene 23 (55) , pp. 8992-8996. 10.1038/sj.onc.1208143

Shaw, Paul and Agrawal, R. 2004. Pleurodesis for malignant pleural effusions. Cochrane Database of Systematic Reviews 2004 (1) , CD002916. 10.1002/14651858.CD002916.pub2

Xu, Mingxu, Cheng, Ning, Gui, Liming, Lai, Mouyi, Wang, Ying, Xia, Donglan, Rui, Min, Zhang, Yingmei and Ma, Dalong 2004. The 5′-upstream region of human programmed cell death 5 gene contains a highly active TATA-less promoter that is up-regulated by etoposide. Gene 329 , pp. 39-49. 10.1016/j.gene.2003.12.025

2003

Dixon, P. F., Avery, S., Chambers, E., Feist, S., Mandhar, H., Parry, Lee, Stone, D. M., Stremmen, H. K., Thurlow, J. K., Lui, C. Tsin-yee and Way, K. 2003. Four years of monitoring for viral haemorrhagic septicaemia virus in marine waters around the United Kingdom. Disease of Aquatic Organisms 54 (3) , pp. 175-186. 10.3354/dao054175

Feng, Gui-Jie, Kellett, Elaine, Scorer, Carol A., Wilde, Jonathan, White, Julia H. and Milligan, Graeme 2003. Selective interactions between helix VIII of the human μ-opioid receptors and the C terminus of periplakin disrupt G protein activation. Journal of Biological Chemistry 278 (35) , pp. 33400-33407. 10.1074/jbc.M305866200

Jones, Gareth E., Prigmore, Elena, Calvez, Ronan, Hogan, Catherine, Dunn, Graham A., Hirsch, Emilio, Wymann, Matthias P. and Ridley, Anne J. 2003. Requirement for PI 3-kinase γ in macrophage migration to MCP-1 and CSF-1. Experimental Cell Research 290 (1) , pp. 120-131. 10.1016/S0014-4827(03)00318-5

Meniel, Valerie and Clarke, Alan Richard 2003. Wnt-Cadherin connections in normal and neoplastic mammary epithelium. Journal of Mammary Gland Biology and Neoplasia 8 (4) , pp. 435-447. 10.1023/B:JOMG.0000017430.12210.37

Milligan, G., Ward, Richard J., Feng, Gui-Jie, Carrillo, Juan J. and McLean, Alison J. 2003. Using receptor-G-Protein chimeras to screen for drugs. In: Bradshaw, Ralph A. and Dennis, Edward A. eds. Handbook of Cell Signaling, Vol. 1. San Diego: Academic Press, pp. 619-621.

Smalley, Matthew John and Ashworth, Alan 2003. Stem cells and breast cancer: A field in transit. Nature Reviews Cancer 3 , pp. 832-844. 10.1038/nrc1212

2002

Adams, G. B., Chabner, K. T., Foxall, R. T., Weibrecht, K. W., Rodrigues, Neil, Dombkowski, D., Fallon, R., Poznansky, M. C. and Scadden, D. T. 2002. Heterologous cells cooperate to augment stem cell migration, homing, and engraftment. Blood 101 (1) , pp. 45-51. 10.1182/blood-2002-02-0486

Clarkson, Richard W. E. 2002. lkB kinase alpha: a link in the chain of the mammary cycle. Breast Cancer Research 4 , 173. 10.1186/bcr446

Cullingworth, Jan, Hooper, Martin L., Harrison, David J., Mason, John O., Sirard, Christian, Patek, Charles E. and Clarke, Alan Richard 2002. Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes. Oncogene 21 (30) , pp. 4696-4701. 10.1038/sj.onc.1205673

Feng, Gui Jie, Cavalli, Antonella and Milligan, Graeme 2002. Engineering a V2 vasopressin receptor agonist- and regulator of G-protein-signaling-sensitive G protein. Analytical Biochemistry 300 (2) , pp. 212-220. 10.1006/abio.2001.5448

Gallagher, Ronald C. J., Hay, Trevor, Meniel, Valerie, Naughton, Catherine, Anderson, Thomas J., Shibata, Hiroyuki, Ito, Masaki, Clevers, Hans, Noda, Tetsuo, Sansom, Owen J., Mason, John O. and Clarke, Alan Richard 2002. Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. Oncogene 21 (42) , pp. 6446-6457. 10.1038/sj.onc.1205892

Harper, M. J. and Clarke, Alan Richard 2002. Low frequency ultrasonic propagation through fibre reinforced, polymer composites. Ultrasonics 40 (1-8) , pp. 555-560. 10.1016/S0041-624X(02)00169-5

Menke, Aswin L., Clarke, Alan Richard, Leitch, Andrea, Ijpenberg, Annemeike, Williamson, Kathy A., Spraggon, Lee, Harrison, David J. and Hastie, Nicholas D. 2002. Genetic interactions between the Wilms' tumor 1 gene and the p53 gene. Cancer Research 62 (22) , pp. 6615-6620.

Morse, Nerys R., Meniel, Valerie and Waters, Raymond 2002. Photoreactivation of UV-induced cyclobutane primidine dimers in the MFA2 gene of S. cerevisiae. Nucleic Acids Research 30 (8) , pp. 1799-1807. 10.1093/nar/30.8.1799

2001

Cheng, T., Shen, H., Rodrigues, Neil, Stier, S. and Scadden, D. T. 2001. Transforming growth factor β1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1or p27Kip1. Blood 98 (13) , pp. 3643-3649. 10.1182/blood.V98.13.3643

Han, Wenling, Lou, Yaxin, Tang, Junmin, Zhang, Yingmei, Chen, Yingyu, Li, Ying, Gu, Weifeng, Hueng, Jiaqiang, Gui, Liming, Tang, Yan, Li, Feng, Song, Quansheng, Di, Chunhui, Wang, Lu, Shi, Qun, Sun, Ronghua, Xia, Donglan, Rui, Min, Tang, Jian and Ma, Dalong 2001. Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. Biochemical Journal 357 (1) , pp. 127-135. 10.1042/0264-6021:3570127

Hodges, Angela K., Li, Shaowei, Maynard, Julie Helen, Parry, Lee, Braverman, Richard, DeClue, Jeffrey E., Cheadle, Jeremy Peter and Sampson, Julian Roy 2001. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin. Human Molecular Genetics 10 (25) , pp. 2899-9205. 10.1093/hmg/10.25.2899

Parry, Lee, Maynard, Julie Helen, Patel, A., Clifford, S. C., Morrissey, C., Maher, E. R., Cheadle, Jeremy Peter and Sampson, Julian Roy 2001. Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas. British Journal of Cancer 85 , pp. 1226-1230. 10.1054/bjoc.2001.2072

Patel, Girish, Taylor, D. and Anstey, Alexander Vincent 2001. No need for sunscreen or occlusive dressings for benign naevi during routine phototherapy [Letter]. Photodermatology, Photoimmunology & Photomedicine 17 (5) , pp. 245-246. 10.1111/j.1600-0781.2001.170508.x

Patel, Girish Khandubhai and Anstey, Alexander Vincent 2001. Rifampicin-induced lupus erythematosus. Clinical and Experimental Dermatology 26 (3) , pp. 260-262. 10.1046/j.1365-2230.2001.00809.x

Sansom, Owen J., Stark, Lesley A., Dunlop, Malcolm G. and Clarke, Alan Richard 2001. Suppression of intestinal and mammary neoplasia by lifetime administration of aspirin in ApcMin/+ and ApcMin/+, Msh2-/- mice. Cancer Research 61 , pp. 7060-7064.

Sansom, Owen J., Toft, Neil J., Winton, Douglas J. and Clarke, Alan Richard 2001. Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner. Oncogene 20 (27) , pp. 3580-3584. 10.1038/sj.onc.1204449

Smalley, Matthew John, Leiper, K., Tootle, R., McCloskey, P., O'Hare, M. J. and Hodgson, H. 2001. Immortalisation of human hepatocytes by temperature-sensitive SV40 large-T antigen. In Vitro Cellular and Developmental Biology - Animal 37 (3) , pp. 166-168. 10.1290/1071-2690(2001)037<0166:IOHHBT>2.0.CO;2

Strathdee, Gordon, Sansom, Owen J., Sim, Alyson, Clarke, Alan Richard and Brown, Robert 2001. A role for mismatch repair in control of DNA ploidy following DNA damage. Oncogene 20 (15) , pp. 1923-1927. 10.1038/sj.onc.1204276

2000

Brain, Katherine Emma, Gray, Jonathon, Norman, Paul, France, Elizabeth, Anglim, Cathy, Barton, Garry, Parsons, Evelyn Patricia, Clarke, Alan Richard, Sweetland, Helen Margaret, Tischkowitz, Marc, Myring, Jenny, Stansfield, Kate, Webster, David, Gower-Thomas, Kate, Daoud, Raouf, Gateley, Chris, Montpenny, Ian, Singhal, Hemant, Branston, Lucy, Sampson, Julian Roy, Roberts, Elizabeth, Newcombe, Robert Gordon, Cohen, David, Rogers, Cerilan, Mansel, Robert Edward and Harper, Peter Stanley 2000. Randomized trial of a specialist genetic assessment service for familial breast cancer. Journal of the National Cancer Institute 92 (16) , pp. 1345-1351. 10.1093/jnci/92.16.1345

Chapman, Rachel S., Duff, Eleanor K., Lourenco, Paula C., Tonner, Elizabeth, Flint, David J., Clarke, Alan Richard and Watson, Christine J. 2000. A novel role for IRF-1 as a suppressor of apoptosis. Oncogene 19 (54) , pp. 6386-6391. 10.1038/sj.onc.1204016

Chapman, Rachel S., Lourenco, Paula, Tonner, Elizabeth, Flint, David, Selbert, Stefan, Takeda, Kyoshi, Akira, Shizuo, Clarke, Alan Richard and Watson, Christine J. 2000. The role of Stat3 in apoptosis and mammary gland involution. In: Mol, Jan A. and Clegg, Roger A. eds. Biology of the Mammary Gland, Advances in Experimental Medicine and Biology, Kluwer, pp. 129-138. (10.1007/0-306-46832-8_16)

Cheng, Tao, Rodrigues, Neil, Shen, Hongmei, Yang, Yong-Guang, Dombkowski, David, Sykes, Megan and Scadden, David T. 2000. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287 (5459) , pp. 1804-1808. 10.1126/science.287.5459.1804

Clarke, Alan Richard 2000. Manipulating the germline: Its impact on the study of carcinogenesis. Carcinogenesis 21 (3) , pp. 435-441. 10.1093/carcin/21.3.435

Gordon, K., Binas, B., Chapman, R. S., Kurian, K. M., Clarkson, Richard W. E., Clark, A. J., Lane, E. B. and Watson, C. J. 2000. A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Research 2 , pp. 222-235. 10.1186/bcr57
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MacKenzie, Alasdair, Payne, Catherine, Boyle, Shelagh, Clarke, Alan Richard and Quinn, John P. 2000. The human preprotachykinin-A gene promoter has been highly conserved and can drive human-like marker gene expression in the adult mouse CNS. Molecular and Cellular Neuroscience 16 (5) , pp. 620-630. 10.1006/mcne.2000.0902

Naylor, S., Smalley, Matthew John, Robertson, D., Gusterson, B. A., Edwards, P. A. and Dale, Trevor Clive 2000. Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium. Journal of Cell Science 113 (12) , pp. 2129-2138.

Nunez, Fatima, Chipchase, Michael D., Clarke, Alan Richard and Melton, David W. 2000. Nucleotide excision repair gene (ERCC1) deficiency causes G2 arrest in hepatocytes and a reduction in liver binucleation: The role of p53 and p21. Faseb Journal 14 (9) , pp. 1073-1082.

Parry, Lee, Maynard, Julie Helen, Patel, Amit, Hodges, Angela, von Deimling, Andreas, Sampson, Julian Roy and Cheadle, Jeremy Peter 2000. Molecular analysis of the TSC1 and TSC2 tumour suppressor genes in sporadic glial and glioneuronal tumours. Human Genetics 107 (4) , pp. 350-356. 10.1007/s004390000390

Sansom, Owen J. and Clarke, Alan Richard 2000. P53 null mice: damaging the hypothesis? Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 452 (2) , pp. 149-162. 10.1016/S0027-5107(00)00089-0

Sarkar, L., Cobourne, M., Naylor, S., Smalley, Matthew John, Dale, Trevor Clive and Sharpe, P. T. 2000. Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development. Proceedings of the National Academy of Sciences of the United States of America 97 (9) , pp. 4520-4524. 10.1073/pnas.97.9.4520

Toft, Neil J., Sansom, Owen J., Brookes, Roger A., Arends, Mark J., Wood, Michelle, Margison, Geoffrey P., Winton, Douglas J. and Clarke, Alan Richard 2000. In vivo administration of O6-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine. Carcinogenesis 21 (4) , pp. 593-598.

Webster, M. T., Rozycka, M., Sara, Elizabeth, Davis, E., Smalley, Matthew John, Young, N., Dale, Trevor Clive and Wooster, R. 2000. Sequence variants of the Axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding. Genes Chromosomes and Cancer 28 (4) , pp. 443-453. 10.1002/1098-2264(200008)28:4<443::AID-GCC10>3.0.CO;2-D

1999

Feng, Gui-Jie, Goodridge, Helen S., Harnett, Margaret M., Wei, Xiao Qing, Nikolaev, Andrei V., Higson, Adrian P. and Liew, Foo -Y. 1999. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. Journal of Immunolgy 163 (12) , pp. 6403-6412.

Smalley, Matthew John and Dale, Trevor Clive 1999. Wnt signalling in mammalian development and cancer. Cancer and Metastasis Reviews 18 (2) , pp. 215-230. 10.1023/A:1006369223282

Smalley, Matthew John, Fraser, Elizabeth, Paterson, Hugh, Naylor, Stuart, Cook, David, Jayatilake, Hiran, Fryer, Lee G., Hutchinson, Lisa, Fry, Michael J. and Dale, Trevor C. 1999. Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO Journal 18 (10) , pp. 2823-2835. 10.1093/emboj/18.10.2823

Smalley, Matthew John, Leiper, K., Floyd, D., Mobberley, M., Ryder, T., Selden, C., Roberts, Eve A. and Hodgson, H. 1999. Behavior of a cell line derived from normal human hepatocytes on non-physiological and physiological-type substrates: Evidence for enhancement of secretion of liver-specific proteins by a three-dimensional growth pattern. In Vitro Cellular and Developmental Biology - Animal 35 (1) , pp. 22-32. 10.1007/s11626-999-0040-6

Smalley, Matthew John, Titley, J., Paterson, H., Perusinghe, N., Clarke, C. and O'Hare, M. J. 1999. Differentiation of separated mouse mammary luminal epithelial and myoepithelial cells cultured on EHS matrix analyzed by indirect immunofluorescence of cytoskeletal antigens. Journal of Histochemistry & Cytochemistry 47 (12) , pp. 1513-1524. 10.1177/002215549904701203

1998

McInnes, Iain B., Leung, Bernard P., Feng, Gui-Jie, Sturrock, Roger D., Field, Max and Foo, Y. Liew 1998. Reply to - a role for IL-15 in rheumatoid arthritis? Nature Medicine 4 , p. 643. 10.1038/nm0698-643b

Smalley, Matthew John, Titley, J. and O'Hare, M. J. 1998. Clonal characterization of mouse mammary luminal epithelial and myoepithelial cells separated by fluorescence-activated cell sorting. In Vitro Cellular and Developmental Biology - Animal 34 (9) , pp. 711-721. 10.1007/s11626-998-0067-0

1997

Dixon, P.F., Feist, S., Kehoe, E., Parry, Lee, Stone, D.M. and Way, K. 1997. Isolation of viral haemorrhagic septicaemia virus from Atlantic herring Clupea harengus from the Atlantic herring Clupea harengus from the English channel. Diseases of Aquatic Organisms 30 (2) , pp. 81-89.

Parry, Lee and Dixon, P. F. 1997. Stability of nine viral haemorrhagic septicaemia virus (VHSV) isolates in seawater. Bulletin of the European Association of Fish Pathologists 17 (1) , pp. 31-36.
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1996

Huang, F. P., Feng, Gui Jie, Lindop, G., Stott, D. I. and Liew, F. W. 1996. The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRLMP-lprlpr mice. Journal of Experimental Medicine 183 (4) , pp. 1447-1459. 10.1084/jem.183.4.1447

1985

Zhao, Dayao, Feng, Gui-Jie, Wu, Xiru and Zuo, Qihua 1985. Seizures induced by intraventricular microinjection of ionised cobalt in the rat -- a new experimental model of epilepsy. Brain Research 342 (2) , pp. 323-329. 10.1016/0006-8993(85)91132-1

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