![]() | Up a level |
Ipseiz, Natacha, Pickering, Robert J., Rosas, Marcela, Tyrrell, Victoria J., Davies, Luke C., Orr, Selinda J., Czubala, Magdalena A., Fathalla, Dina, Robertson, Avril A. B., Bryant, Clare E., O'Donnell, Valerie and Taylor, Philip R.
2020.
Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway.
EMBO Journal
39
(14)
, e103454.
10.15252/embj.2019103454
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Thompson, Aiysha, Griffiths, James S., Walker, Louise, Matos da Fonseca, Diogo, Lee, Keunsook K., Taylor, Philip R., Gow, Neil A. R. and Orr, Selinda J.
2019.
Dependence on Dectin-1 varies with multiple candida species.
Frontiers in Microbiology
10
, 1800.
10.3389/fmicb.2019.01800
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Thompson, Aiysha, Davies, Luke C., Liao, Chia-Te, da Fonseca, Diogo M., Griffiths, James S., Andrews, Robert, Jones, Adam V., Clement, Mathew, Brown, Gordon D., Humphreys, Ian R., Taylor, Philip R. and Orr, Selinda J.
2019.
The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.
PLoS Pathogens
15
(6)
, e1007850.
10.1371/journal.ppat.1007850
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Patin, Emmanuel C., Thompson, Aiysha and Orr, Selinda J. 2019. Pattern recognition receptors in fungal immunity. Seminars in Cell & Developmental Biology 89 , pp. 24-33. 10.1016/j.semcdb.2018.03.003 |
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McLaren, James, Clement, Mathew, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J., Ladell, Kristin, Price, David A. and Humphreys, Ian R.
2019.
IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea.
Journal of Immunology
202
(3)
, pp. 943-955.
10.4049/jimmunol.1701757
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Griffiths, James S., Thompson, Aiysha, Stott, Matthew, Benny, Ankita, Lewis, Natalie A., Taylor, Philip R., Forton, Julian, Herrick, Sarah, Orr, Selinda J. and McGreal, Eamon P.
2018.
Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases.
FASEB Journal
32
(6)
, pp. 3385-3397.
10.1096/fj.201701145R
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Thompson, Aiysha and Orr, Selinda J
2018.
Emerging IL-12 family cytokines in the fight against fungal infections.
Cytokine
(111)
, pp. 398-407.
10.1016/j.cyto.2018.05.019
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Patin, Emmanuel C., Orr, Selinda Jane and Schaible, Ulrich E. 2017. Macrophage inducible C-type lectin as a multifunctional player in immunity. Frontiers in Immunology 8 , 861. 10.3389/fimmu.2017.00861 |
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Patin, Emmanuel, Jones, Adam V., Thompson, Aiysha, Clement, Mathew, Liao, Chia-Te, Griffiths, James S., Wallace, Leah, Bryant, Clare E., Lang, Roland, Rosenstiel, Philip, Humphreys, Ian R., Taylor, Philip Russel, Jones, Gareth Wyn and Orr, Selinda Jane
2016.
IL-27 induced by Select Candida spp. via TLR7/NOD2 signaling and IFN-β production inhibits fungal clearance.
The Journal of Immunology
197
(1)
, pp. 208-221.
10.4049/jimmunol.1501204
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Burg, A., Quigley, L., Jones, Adam V., O'Connor, G., Boelte, K., McVicar, D. and Orr, Selinda Jane 2016. Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity. SpringerPlus 5 , 815. 10.1186/s40064-016-2501-1 |
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Patin, Emmanuel C., Willcocks, Sam, Orr, Selinda Jane, Ward, Theresa H., Lang, Roland and Schaible, Ulrich E.
2016.
Mincle-mediated anti-inflammatory IL-10 response counter-regulates IL-12 in vitro.
Innate Immunity
22
(3)
, pp. 181-185.
10.1177/1753425916636671
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Bryant, Clare E., Orr, Selinda Jane, Ferguson, Brian, Symmons, Martyn F., Boyle, Joseph P. and Monie, Tom P. 2015. International union of basic and clinical pharmacology. XCVI. Pattern recognition receptors in health and disease. Pharmacological Reviews 67 (2) , pp. 462-504. 10.1124/pr.114.009928 |
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Cardone, Marco, Dzutsev, Amiran K., Li, Hongchuan, Riteau, Nicolas, Gerosa, Franca, Shenderov, Kevin, Winkler-Pickett, Robin, Provezza, Lisa, Riboldi, Elena, Leighty, Robert M., Orr, Selinda Jane, Steinhagen, Folkert, Wewers, Mark D., Sher, Alan, Anderson, Stephen K., Goldszmid, Romina, McVicar, Daniel W., Lyakh, Lyudmila and Trinchieri, Giorgio
2014.
Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.
PLoS ONE
9
(12)
, e114516.
10.1371/journal.pone.0114516
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Orr, Selinda Jane, Burg, Ashley R., Chan, Tim, Quigley, Laura, Jones, Gareth Wyn, Ford, Jill W., Hodge, Deborah, Razzook, Catherine, Sarhan, Joseph, Jones, Yava L., Whittaker, Gillian C., Boelte, Kimberly C., Lyakh, Lyudmila, Cardone, Marco, O'Connor, Geraldine M., Tan, Cuiyan, Li, Hongchuan, Anderson, Stephen K., Jones, Simon Arnett, Zhang, Weiguo, Taylor, Philip Russel, Trinchieri, Giorgio and McVicar, Daniel W. 2013. LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells. PLoS Pathogens 9 (5) , e1003357. 10.1371/journal.ppat.1003357 |
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Karsten, Christian M., Pandey, Manoj K., Figge, Julia, Kilchenstein, Regina, Taylor, Philip Russel, Rosas, Marcela, McDonald, Jacqueline U., Orr, Selinda Jane, Berger, Markus, Petzold, Dominique, Blanchard, Veroniqué, Winkler, André, Hess, Constanze, Reid, Delyth M., Majoul, Irina V., Strait, Richard T., Harris, Nathaniel L., Köhl, Gabriele, Wex, Eva, Ludwig, Ralf, Zillikens, Detlef, Nimmerjahn, Falk, Finkelman, Fred D., Brown, Gordon D., Ehlers, Marc and Köhl, Jörg 2012. Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1 [Letter]. Nature Medicine 18 (9) , pp. 1401-1406. 10.1038/nm.2862 |
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Orr, Selinda Jane, Roessler, S., Quigley, L., Chan, T., Ford, J. W., O'Connor, G. M. and McVicar, D. W. 2010. Implications for gene therapy-limiting expression of IL-2R c delineate differences in signaling thresholds required for lymphocyte development and maintenance. The Journal of Immunology 185 (3) , pp. 1393-1403. 10.4049/jimmunol.0903528 |
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Orr, Selinda Jane and McVicar, D. W. 2010. LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes? Journal of Leukocyte Biology 89 (1) , pp. 11-19. 10.1189/jlb.0410221 |
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Whittaker, Gillian C., Orr, Selinda Jane, Quigley, Laura, Hughes, Laurel, Francischetti, Ivo M. B., Zhang, Weigou and McVicar, Daniel W. 2010. The linker for activation of B cells (LAB)/Non-T Cell Activation Linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage Inflammatory responses independently of the linker for activation of T cells. Journal of Biological Chemistry 285 (5) , pp. 2976-2985. 10.1074/jbc.M109.038398 |
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Orr, Selinda Jane, Quigley, Laura and McVicar, Daniel W. 2009. In vivo expression of signaling proteins in reconstituted NK cells. Journal of Immunological Methods 340 (2) , pp. 158-163. 10.1016/j.jim.2008.10.014 |
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Boyd, C. R., Orr, Selinda Jane, Spence, S., Burrows, J. F., Elliott, J., Carroll, H. P., Brennan, K., Gabhann, J. N., Coulter, W. A., Johnston, J. A. and Jefferies, C. A. 2009. Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production. The Journal of Immunology 183 (12) , pp. 7703-7709. 10.4049/jimmunol.0902780 |
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Whittaker, Gillian C., Burshtyn, Deborah N., Orr, Selinda Jane, Quigley, Laura, Hodge, Deborah L., Pascal, Veronique, Zhang, Weiguo and McVicar, Daniel W. 2008. Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire. Blood 112 (7) , pp. 2869-2877. 10.1182/blood-2007-11-121590 |
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Scott, Christopher J., Marouf, Waleed M., Quinn, Derek J., Buick, Richard J., Orr, Selinda J., Donnelly, Ryan F. and McCarron, Paul A. 2008. Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles. Pharmaceutical Research 25 (1) , pp. 135-146. 10.1007/s11095-007-9400-7 |
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Orr, S. J., Morgan, N. M., Elliott, J., Burrows, J. F., Scott, C. J., McVicar, D. W. and Johnston, J. A. 2007. CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover. Blood 109 (3) , pp. 1061-1068. 10.1182/blood-2006-05-023556 |
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Orr, S. J., Morgan, N. M., Buick, R. J., Boyd, C. R., Elliott, J., Burrows, J. F., Jefferies, C. A., Crocker, P. R. and Johnston, J. A. 2006. SOCS3 targets siglec 7 for proteasomal degradation and blocks siglec 7-mediated responses. Journal of Biological Chemistry 282 (6) , pp. 3418-3422. 10.1074/jbc.C600216200 |
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