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Number of items: 21.

Greenshields Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L., Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J., Gallimore, Awen M., Sewell, Andrew J. and Cole, David K. 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32 (2) , 107885. 10.1016/j.celrep.2020.107885
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MacLachlan, Bruce J., Dolton, Garry, Papakyriakou, Athanasios, Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea, Besneux, Matthieu, Szomolay, Barbara, Elliott, Tim, Sewell, Andrew K., Gallimore, Awen, Rizkallah, Pierre, Cole, David K. and Godkin, Andrew 2019. Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. Journal of Biological Chemistry 294 (52) , pp. 20246-20258. 10.1074/jbc.RA119.009437
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Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K. and Sewell, Andrew K. 2019. TCR-induced alteration of primary MHC peptide anchor residue. European Journal of Immunology 49 (7) , pp. 1052-1066. 10.1002/eji.201948085
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Cole, David K., Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, John J., Schauenburg, Andrea J. A., Beck, Konrad, Evavold, Brian D., Rizkallah, Pierre J. and Sewell, Andrew K. 2017. Dual molecular mechanisms govern escape at immunodominant HLA A2-restricted HIV epitope. Frontiers in Immunology 8 , 1503. 10.3389/fimmu.2017.01503
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Jones, Nicholas, Cronin, James G., Dolton, Garry, Panetti, Silvia, Schauenburg, Andrea, Galloway, Sarah A. E., Sewell, Andrew K., Cole, David K., Thornton, Catherine A. and Francis, Nigel J. 2017. Metabolic adaptation of human CD4+ and CD8+ T-Cells to T-Cell receptor-mediated stimulation. Frontiers in Immunology 8 , 1516. 10.3389/fimmu.2017.01516
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MacLachlan, Bruce J., Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea J., Bianchi, Valentina, Rizkallah, Pierre J., Sewell, Andrew K., Fuller, Anna and Cole, David K. 2017. Using X-ray crystallography, biophysics, and functional assays to determine the mechanisms governing T-cell receptor recognition of cancer antigens. Journal of Visualized Experiments (120) , e54991. 10.3791/54991
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Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D, Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew, Laugel, Bruno, Rizkallah, Pierre J., Wooldridge, Linda and Sewell, Andrew K 2017. Structural mechanism underpinning cross-reactivity of a CD8+ T-cell clone that recognises a peptide derived from human telomerase reverse transcriptase. Journal of Biological Chemistry 292 (3) , pp. 802-813. 10.1074/jbc.M116.741603
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Szomolay, Barbara, Liu, Jie, Brown, Paul E., Miles, John J., Clement, Mathew, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J., Sewell, Andrew, Burrows, Scott R., Roederer, Mario, Price, David A/, Wooldridge, Linda and van den Berg, Hugo A. 2016. Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors. Immunology and Cell Biology 94 (6) , pp. 573-582. 10.1038/icb.2016.12
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Schauenburg, Andrea J. A. 2016. Molecular mechanisms underlying pMHC-II recognition. PhD Thesis, Cardiff University.
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Holland, Christopher J., Dolton, Garry M., Scurr, Martin, Ladell, Kristin, Schauenburg, Andrea J., Miners, Kelly, Madura, Florian, Sewell, Andrew K., Price, David A., Cole, David K. and Godkin, Andrew J. 2015. Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers. Journal of Immunology 195 (12) , pp. 5827-5836. 10.4049/jimmunol.1402787
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Neller, Michelle A., Ladell, Kristin Ingrid, McLaren, James Edward, Matthews, Katherine K., Gostick, Emma, Pentier, Johanne, Dolton, Garry Michael, Schauenburg, Andrea J. A., Koning, Dan, Fontaine Costa, Ana Isabel C. A., Watkins, Thomas S., Venturi, Vanessa, Smith, Corey, Khanna, Rajiv, Miners, Kelly Louise, Clement, Mathew, Wooldridge, Linda, Cole, David, van Baarle, Debbie, Sewell, Andrew K., Burrows, Scott R., Price, David and Miles, John James 2015. Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics. Immunology and Cell Biology 93 , pp. 625-633. 10.1038/icb.2015.17
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Madura, Florian, Rizkallah, Pierre, Holland, Christopher J., Fuller, Anna, Bulek, Anna Marta, Godkin, Andrew James, Schauenburg, Andrea J., Cole, David K. and Sewell, Andrew K. 2015. Structural basis for ineffective T-cell responses to MHC anchor residue-improved 'heteroclitic' peptides. European Journal of Immunology 45 (2) , pp. 584-591. 10.1002/eji.201445114
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Tungatt, Katie, Bianchi, Valentina, Crowther, Michael D., Powell, Wendy, Schauenburg, Andrea J. A., Trimby, Andrew R., Donia, M., Miles, John James, Holland, Christopher J., Cole, David, Godkin, Andrew James, Peakman, M., Straten, P. T., Svane, I. M., Sewell, Andrew K. and Dolton, Garry Michael 2015. Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs. Journal of Immunology 194 (1) , pp. 463-474. 10.4049/jimmunol.1401785
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Kløverpris, Henrik N., Cole, David, Fuller, Anna, Carlson, Jonathan, Beck, Konrad, Schauenburg, Andrea J. A., Rizkallah, Pierre, Buus, Søren, Sewell, Andrew K. and Goulder, Philip 2015. A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology 12 (1) , 20. 10.1186/s12977-015-0149-5
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Madura, Florian, Rizkallah, Pierre, Miles, Kim Michelle, Holland, Christopher J., Bulek, Anna Marta, Fuller, Anna, Schauenburg, Andrea J. A., Miles, John James, Liddy, Nathaniel, Sami, M., Li, Y., Hossain, M., Baker, B. M., Jakobsen, B. K., Sewell, Andrew K. and Cole, David 2013. T-cell receptor specificity maintained by altered thermodynamics. Journal of Biological Chemistry 288 (26) , pp. 18766-18775. 10.1074/jbc.M113.464560

Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David, Burrows, Scott R., Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Cole, David, Miles, Kim Michelle, Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J. A., Godkin, Andrew James, Bulek, Anna Marta, Fuller, Anna, Akpovwa, Hephzibah, Pymm, Phillip G., Liddy, N., Sami, M., Li, Y., Rizkallah, Pierre, Jakobsen, B. K. and Sewell, Andrew K. 2013. T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions. Journal of Biological Chemistry 289 (2) , pp. 628-638. 10.1074/jbc.M113.522110
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Bulek, Anna Marta, Madura, Florian, Fuller, Anna, Holland, Christopher J., Schauenburg, Andrea J. A., Sewell, Andrew K., Rizkallah, Pierre and Cole, David 2012. TCR/pMHC optimized protein crystallization screen. Journal of Immunological Methods 382 (1-2) , pp. 203-210. 10.1016/j.jim.2012.06.007

Clement, Mathew, Ladell, Kristin Ingrid, Ekeruche, Julia, Miles, John James, Edwards, Emily, Dolton, Garry Michael, Williams, Tamsin, Schauenburg, Andrea J. A., Cole, David, Lauder, Sarah Nicol, Gallimore, Awen Myfanwy, Godkin, Andrew James, Burrows, Scott R., Price, David, Sewell, Andrew K. and Wooldridge, Linda 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187 (2) , pp. 654-663. 10.4049/jimmunol.1003941

Miles, John James, Bulek, Anna Marta, Cole, David, Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry Michael, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David, Rizkallah, Pierre and Sewell, Andrew K. 2010. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathogens 6 (11) , e1001198. 10.1371/journal.ppat.1001198
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This list was generated on Sat Oct 24 04:18:10 2020 BST.


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