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Browse by Current Cardiff authors

Number of items: 42.

Petersen, Ole H., Gerasimenko, Oleg V. and Gerasimenko, Julia V. 2020. Endocytic uptake of SARS-CoV-2: the critical roles of pH, Ca2+ and NAADP. Function , zqaa003. 10.1093/function/zqaa003

Jakubowska, Monika A., Kerkhofs, Martijn, Martines, Claudio, Efremov, Dimitar G., Gerasimenko, Julia V., Gerasimenko, Oleg V., Petersen, Ole H., Bultynck, Geert, Vervliet, Tim and Ferdek, Pawel E. 2019. ABT‐199 (Venetoclax), a BH3‐mimetic Bcl‐2 inhibitor, does not cause Ca2+‐signalling dysregulation or toxicity in pancreatic acinar cells. British Journal of Pharmacology 176 (22) 10.1111/bph.14505

Peng, Shuang, Gerasimenko, Julia V., Tsugorka, Tetyana M., Gryshchenko, Oleksiy, Samarasinghe, Sujith, Petersen, Ole H. and Gerasimenko, Oleg V. 2018. Galactose protects against cell damage in mouse models of acute pancreatitis. Journal of Clinical Investigation 128 (9) 10.1172/JCI94714

Vervliet, Tim, Gerasimenko, Julia V., Ferdek, Pawel E., Jakubowska, Monika A., Petersen, Ole H., Gerasimenko, Oleg V. and Bultynck, Geert 2018. BH4 domain peptides derived from Bcl-2/Bcl-XL as novel tools against acute pancreatitis. Cell Death Discovery 4 (1) , 58. 10.1038/s41420-018-0054-5

Gerasimenko, Julia V., Peng, Shuang, Tsugorka, Tetyana and Gerasimenko, Oleg V. 2018. Ca 2+ signalling underlying pancreatitis. Cell Calcium 70 , pp. 95-101. 10.1016/j.ceca.2017.05.010

Ferdek, Pawel E., Jakubowska, Monika A., Polina, Nicolaou, Gerasimenko, Julia V., Gerasimenko, Oleg V. and Petersen, Ole H. 2017. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides. Cell Death and Disease 8 , e2640. 10.1038/cddis.2017.41

Bittremieux, Mart, Gerasimenko, Julia Vladimirovna, Schuermans, Marleen, Luyten, Tomas, Stapleton, Eloise, Alzayady, Kamil J., De Smedt, Humbert, Yule, David I., Mikoshiba, Katsuhiko, Vangheluwe, Peter, Gerasimenko, Oleg Vsevolodovich, Parys, Jan B. and Bultynck, Geert 2017. DPB162-AE, an inhibitor of store-operated Ca2+ entry, can deplete the endoplasmic reticulum Ca2+ store. Cell Calcium 62 , pp. 60-70. 10.1016/j.ceca.2017.01.015

Ferdek, Pawel E., Jakubowska, Monika A., Gerasimenko, Julia V., Gerasimenko, Oleg V. and Petersen, Ole H. 2016. Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium-driven bile uptake. Journal of Physiology 594 (21) , pp. 6147-6164. 10.1113/JP272774

Peng, Shuang, Gerasimenko, Julia V., Tsugorka, Tatiana, Gryshchenko, Oleksiey, Samarasinghe, Sujith, Petersen, Ole H. and Gerasimenko, Oleg V. 2016. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 371 (1700) , 20150423. 10.1098/rstb.2015.0423

Jakubowska, Monika A., Ferdek, Pawel E., Gerasimenko, Oleg V., Gerasimenko, Julia V. and Petersen, Ole H. 2016. Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biology 6 , 160149. 10.1098/rsob.160149

Gryshchenko, Oleksiy, Gerasimenko, Julia Vladimirovna, Gerasimenko, Oleg Vsevolodovich and Petersen, Ole Holger 2016. Calcium signalling in pancreatic stellate cells: mechanisms and potential roles. Cell Calcium 59 (2-3) , pp. 140-144. 10.1016/j.ceca.2016.02.003

Gerasimenko, Julia Vladimirovna, Peng, Shuang and Gerasimenko, Oleg Vsevolodovich 2014. Role of acidic stores in secretory epithelia. Cell Calcium 55 (6) , pp. 346-354. 10.1016/j.ceca.2014.04.002

Gerasimenko, Julia Vladimirovna, Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2014. Monitoring of intra-ER free Ca2+. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling 3 (3) , pp. 63-71. 10.1002/wmts.106

Gerasimenko, Julia Vladimirovna, Gerasimenko, Oleg Vsevolodovich and Petersen, Ole Holger 2014. The role of Ca2+ in the pathophysiology of pancreatitis. The Journal of Physiology 592 (2) , pp. 269-280. 10.1113/jphysiol.2013.261784

Gerasimenko, Julia Vladimirovna, Gryshchenko, Oleksiy, Ferdek, Pawel, Stapleton, Eloise, Hébert, Tania O.G., Bychkova, Solomiia, Peng, Shuang, Begg, Malcolm, Gerasimenko, Oleg Vsevolodovich and Petersen, Ole Holger 2013. Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy. Proceedings of the National Academy of Sciences of the United States of America 110 (32) , pp. 13186-13191. 10.1073/pnas.1300910110

Ferdek, Pawel, Gerasimenko, Julia Vladimirovna, Peng, Shuang, Tepikin, Alexei V., Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2012. A novel role for Bcl-2 in regulation of cellular calcium extrusion. Current Biology 22 (13) , pp. 1241-1246. 10.1016/j.cub.2012.05.002

Gerasimenko, Oleg Vsevolodovich, Petersen, Ole Holger and Gerasimenko, Julia Vladimirovna 2012. Role of intracellular acid Ca2+ stores in pathological pancreatic protease activation [Editorial]. Expert Review of Gastroenterology & Hepatology 6 (2) , pp. 129-131. 10.1586/EGH.12.5

Petersen, Ole Holger, Gerasimenko, Oleg Vsevolodovich and Gerasimenko, Julia Vladimirovna 2012. The war within - unraveling the molecular causes of acute pancreatitis - a potentially deadly disease in which the pancreas essentially digests itself - is yielding clues to how it might be treated. The Scientist 26 (2) , pp. 40-44.

Gerasimenko, Oleg Vsevolodovich and Gerasimenko, Julia Vladimirovna 2012. Mitochondrial function and malfunction in the pathophysiology of pancreatitis. Pflugers Archiv European Journal of Physiology 464 (1) , pp. 89-99. 10.1007/s00424-012-1117-8

Petersen, Ole Holger, Gerasimenko, Oleg Vsevolodovich, Tepikin, A. and Gerasimenko, Julia Vladimirovna 2011. Aberrant Ca2+ signalling through acidic calcium stores in pancreatic acinar cells. Cell Calcium 50 (2) , pp. 193-199. 10.1016/j.ceca.2011.02.010

Petersen, Ole Holger, Gerasimenko, Oleg Vsevolodovich and Gerasimenko, Julia Vladimirovna 2011. Pathobiology of acute pancreatitis: focus on intracellular calcium and calmodulin. F1000 Medicine Reports (3) , 15. 10.3410/M3-15

Gerasimenko, Julia Vladimirovna, Lur, György, Ferdek, Pawel, Sherwood, Mark W., Ebisui, Etsuko, Tepikin, Alexei V., Mikoshiba, Katsuhiko, Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2011. Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors. Proceedings of the National Academy of Sciences of the United States of America 108 (14) , pp. 5873-5878. 10.1073/pnas.1016534108

Gerasimenko, Julia Vladimirovna, Ferdek, Pawel, Fischer, Lars, Gukovskaya, Anna and Pandol, Stephen 2010. Inhibitors of Bcl-2 protein family deplete ER Ca2+ stores in pancreatic acinar cells. Pflugers Archiv-European Journal of Physiology 460 (5) , pp. 891-900. 10.1007/s00424-010-0859-4

Gerasimenko, Oleg Vsevolodovich and Gerasimenko, Julia Vladimirovna 2010. Two-photon permeabilization and calcium measurements in cellular organelles. Live Cell Imaging: Methods and Protocols, Vol. 591. Methods in Molecular Biology, vol. 2. Springer, pp. 201-210. (10.1007/978-1-60761-404-3_12)

Baumgartner, H. K., Gerasimenko, Julia Vladimirovna, Thorne, C., Ferdek, Pawel, Pozzan, T., Tepikin, A. V., Petersen, Ole Holger, Sutton, R., Watson, A. J. M. and Gerasimenko, Oleg Vsevolodovich 2009. Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening. Journal of Biological Chemistry 284 (31) , pp. 20796-20803. 10.1074/jbc.M109.025353

Petersen, Ole Holger, Tepikin, A. V., Gerasimenko, Julia Valdimirovna, Gerasimenko, Oleg Vsevolodovich, Sutton, R. and Criddle, D. N. 2009. Fatty acids, alcohol and fatty acid ethyl esters: Toxic Ca2+ signal generation and pancreatitis. Cell Calcium 45 (6) , pp. 634-642. 10.1016/j.ceca.2009.02.005

Gerasimenko, Julia Vladimirovna, Lur, György, Sherwood, Mark W., Ebisui, Etsuko, Tepikin, Alexei V., Mikoshiba, Katsuhiko, Gerasimenko, Oleg Vsevolodovich and Petersen, Ole Holger 2009. Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors. Proceedings of the National Academy of Sciences of the United States of America 106 (26) , pp. 10758-10763. 10.1073/pnas.0904818106

Fedirko, N., Gerasimenko, Julia Vladimirovna, Tepikin, A. V. and Gerasimenko, Oleg Vsevolodovich 2009. Regulation of early response genes in pancreatic acinar cells: external calcium and nuclear calcium signalling aspects. Acta Physiologica 195 (1) , pp. 51-60. 10.1111/j.1748-1716.2008.01935.x

Murphy, J. A., Criddle, D. N., Sherwood, M., Chvanov, M., Mukherjee, R., McLaughlin, E., Booth, D. M, Gerasimenko, Julia Vladimirovna, Raraty, M. G. T., Ghaneh, P, Neoptolemos, J. P., Gerasimenko, Oleg Vsevolodovich, Tepikin, A. V., Green, G. M., Reeve, J. R., Petersen, Ole Holger and Sutton, R. 2008. Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells. Gastroenterology 135 (2) , pp. 632-641. 10.1053/j.gastro.2008.05.026

Baumgartner, H. K., Gerasimenko, Julia Vladimirovna, Thorne, C., Ashurst, L. H., Barrow, S. L., Chvanov, M. A., Gillies, S., Criddle, D. N., Tepikin, A. V., Petersen, Ole Holger, Sutton, R., Watson, A. J. M. and Gerasimenko, Oleg Vsevolodovich 2007. Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins. American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (1) , G296-G307. 10.1152/ajpgi.00103.2007

Criddle, D. N., Gerasimenko, Julia Vladimirovna, Baumgartner, H. K., Jaffar, M., Voronina, S., Sutton, R., Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2007. Calcium signalling and pancreatic cell death: apoptosis or necrosis? Cell Death and Differentiation 14 (7) , pp. 1285-1294. 10.1038/sj.cdd.4402150

Gerasimenko, Julia Vladimirovna, Flowerdew, S. E., Voronina, S. G., Sukhomlin, T. K., Tepikin, A. V., Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2006. Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors. Journal of Biological Chemistry 281 (52) , pp. 40154-40163. 10.1074/jbc.M606402200

Gerasimenko, Julia Vladimirovna, Sherwood, Mark, Tepikin, Alexei, Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2006. NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area. Journal of Cell Science 119 (2) , pp. 226-238. 10.1242/jcs.02721

Dolman, Nick J., Gerasimenko, Julia Vladimirovna, Gerasimenko, Oleg Vsevolodovich, Voronina, Svetlana G., Petersen, Ole Holger and Tepikin, Alexei V. 2005. Stable Golgi-mitochondria complexes and formation of Golgi Ca2+ gradients in pancreatic acinar cells. Journal of Biological Chemistry 280 (16) , pp. 15794-15799. 10.1074/jbc.M412694200

Gerasimenko, Oleg Vsevolodovich and Gerasimenko, Julia Vladimirovna 2004. New aspects of nuclear calcium signalling. Journal of Cell Science 117 (15) , pp. 3087-3094. 10.1242/jcs.01295

Gerasimenko, Julia Vladimirovna, Maruyama, Yoshio, Yano, Kojiro, Dolman, Nick J., Tepikin, Alexei V., Petersen, Ole Holger and Gerasimenko, Oleg Vsevolodovich 2003. NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors. Journal of Cell Biology 163 (2) , pp. 271-282. 10.1083/jcb.200306134

Gerasimenko, Oleg Vsevolodovich, Maruyama, Y., Tepikin, Alexei, Petersen, Ole Holger and Gerasimenko, Julia Vladimirovna 2003. Calcium signalling in and around the nuclear envelope. Biochemical Society Transactions 31 (1) , pp. 76-78.

Gerasimenko, Julia Vladimirovna, Maruyama, Y., Tepikin, A., Petersen, Ole Holger and Gerasimenko, O. 2003. Calcium signalling in and around the nuclear envelope. Biochemical Society Transactions 31 (1) , pp. 76-78.

Gerasimenko, Julia Vladimirovna, Gerasimenko, Oleg Vsevolodovich, Palejwala, Altaf, Tepikin, Alexei, Petersen, Ole Holger and Watson, Alistair J. M. 2002. Menadione-induced apoptosis: Roles of cytosolic Ca2+ elevations and the mitochondrial permeability transition pore. Journal of Cell Science 115 , pp. 485-497.

Gerasimenko, Oleg Vsevolodovich, Gerasimenko, Julia Vladimirovna, Rizzuto, R. R., Treiman, M., Tepikin, A. V. and Petersen, Ole Holger 2002. The distribution of the endoplasmic reticulum in living pancreatic acinar cells. Cell Calcium 32 (5-6) , pp. 261-268. 10.1016/S0143416002001938

Gerasimenko, Julia Vladimirovna, Gerasimenko, Oleg Vsevolodovich and Petersen, Ole Holger 2001. Membrane repair: Ca2+-elicited lysosomal exocytosis. Current Biology 11 (23) , R971-R974. 10.1016/S0960-9822(01)00577-2

Cansela, Jose Manuel, Gerasimenko, Oleg Vsevolodovich, Gerasimenko, Julia Vladimirovna, Tepikin, Alexei V. and Petersen, Ole Holger 2000. Two different but converging messenger pathways to intracellular Ca2+ release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphate. Embo Journal 19 (11) , pp. 2549-2557. 10.1093/emboj/19.11.2549

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