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Number of items: 41.

Zelek, Wioleta M., Cole, Jade, Ponsford, Mark J., Harrison, Richard A., Schroeder, Ben E., Webb, Nicholas, Jolles, Stephen, Fegan, Christopher, Morgan, Matt, Wise, Matt P. and Morgan, B. Paul 2020. Complement inhibition with the C5 blocker LFG316 in severe COVID-19. American Journal of Respiratory and Critical Care Medicine 10.1164/rccm.202007-2778LE

Lewis, Thomas, Corcoran, David B., Thurston, David E., Giles, Peter J., Ashelford, Kevin, Walsby, Elisabeth J., Fegan, Christopher D., Pepper, Andrea G.S., Rahman, Khondaker Miraz and Pepper, Chris 2020. Novel pyrrolobenzodiazepine benzofused hybrid molecules inhibit NF-κB activity and synergise with bortezomib and ibrutinib in hematological cancers. Haematologica 10.3324/haematol.2019.238584

Rule, Simon A., Cartron, Guillaume, Fegan, Christopher, Morschhauser, Franck, Han, Lingling, Mitra, Siddhartha, Salles, Gilles and Dyer, Martin J. S. 2020. Long-term follow-up of patients with mantle cell lymphoma (MCL) treated with the selective Bruton's tyrosine kinase inhibitor tirabrutinib (GS/ONO-4059) [Letter]. Leukemia 34 , pp. 1458-1461. 10.1038/s41375-019-0658-7

O'Donnell, Valerie B, Thomas, David, Stanton, Richard, Maillard, Jean-Yves, Murphy, Robert C, Jones, Simon A, Humphreys, Ian, Wakelam, Michael J O, Fegan, Christopher, Wise, Matt P, Bosch, Albert and Sattar, Syed A. 2020. Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection. Function 10.1093/function/zqaa002

Elston, Lauren, Fegan, Chris, Hills, Robert, Hashimdeen, Shaikh S., Walsby, Elisabeth, Henley, Peter, Pepper, Chris and Man, Stephen 2020. Increased frequency of CD4+PD-1+HLA-DR+ T cells is associated with disease progression in CLL. British Journal of Haematology 188 (6) , pp. 872-880. 10.1111/bjh.16260

O'Donnell, Valerie, Thomas, David, Stanton, Richard, Maillard, Jean-Yves, Murphy, Robert C, Jones, Simon, Wakelam, MJO, Fegan, Christopher, Wise, Matthew, Bosch, Albert and Sattar, Syed 2020. Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection. Function 1 (1) 10.1093/function/zqaa002

Cohen, Jared A., Rossi, Francesca Maria, Zucchetto, Antonella, Bomben, Riccardo, Terzi-di-Bergamo, Lodovico, Rabe, Kari G., Degan, Massimo, Steffan, Agostino, Polesel, Jerry, Santinelli, Enrico, Innocenti, Idanna, Cutrona, Giovanna, D' Arena, Giovanni, Pozzato, Gabriele, Zaja, Francesco, Chiarenza, Annalisa, Rossi, Davide, Di Raimondo, Francesco, Laurenti, Luca, Gentile, Massimo, Morabito, Fortunato, Neri, Antonino, Ferrarini, Manlio, Fegan, Christopher D., Pepper, Christopher J., Del Poeta, Giovanni, Parikh, Sameer A., Kay, Neil E. and Gattei, Valter 2019. A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia. Haematologica 104 (11) , 228171. 10.3324/haematol.2019.228171

Escudero, Laura, Cleal, Kez, Ashelford, Kevin, Fegan, Chris, Pepper, Chris, Liddiard, Kate and Baird, Duncan M. 2019. Telomere fusions associate with coding sequence and copy number alterations in CLL. Leukemia 33 , pp. 2093-2097. 10.1038/s41375-019-0423-y

Norris, Kevin, Hillmen, Peter, Rawstron, Andrew, Hills, Robert, Baird, Duncan M., Fegan, Christopher D. and Pepper, Chris 2019. Telomere length predicts for outcome to FCR chemotherapy in CLL. Leukemia 33 , pp. 1953-1963. 10.1038/s41375-019-0389-9

Went, Molly, Sud, Amit, Speedy, Helen, Sunter, Nicola J., Försti, Asta, Law, Philip J., Johnson, David C., Mirabella, Fabio, Holroyd, Amy, Li, Ni, Orlando, Giulia, Weinhold, Niels, van Duin, Mark, Chen, Bowang, Mitchell, Jonathan S., Mansouri, Larry, Juliusson, Gunnar, Smedby, Karin E, Jayne, Sandrine, Majid, Aneela, Dearden, Claire, Allsup, David J., Bailey, James R., Pratt, Guy, Pepper, Chris, Fegan, Chris, Rosenquist, Richard, Kuiper, Rowan, Stephens, Owen W., Bertsch, Uta, Broderick, Peter, Einsele, Hermann, Gregory, Walter M., Hillengass, Jens, Hoffmann, Per, Jackson, Graham H., Jöckel, Karl-Heinz, Nickel, Jolanta, Nöthen, Markus M., da Silva Filho, Miguel Inacio, Thomsen, Hauke, Walker, Brian A., Broyl, Annemiek, Davies, Faith E., Hansson, Markus, Goldschmidt, Hartmut, Dyer, Martin J. S., Kaiser, Martin, Sonneveld, Pieter, Morgan, Gareth J., Hemminki, Kari, Nilsson, Björn, Catovsky, Daniel, Allan, James M. and Houlston, Richard S. 2018. Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology. Blood Cancer Journal 9 , 1. 10.1038/s41408-018-0162-8

Hyatt, Sam, Robinson, Rhiannon, Hepple, Nicole, Grimstead, Julia, Hills, Robert Kerrin, Fegan, Christopher, Jackson, Graham, allan, James, Pratt, Guy, Pepper, Christopher John and Baird, Duncan Martin 2017. Telomere length is a critical determinant for survival in multiple myeloma. British Journal of Haematology 178 (1) , pp. 94-98. 10.1111/bjh.14643

Williams, Jenna, Heppel, Nicole, Britt-Compton, Bethan, Grimstead, Julia, Robinson, Rhiannon, Tauro, Sudhir, Bowen, David, Knapper, Steven, Groves, Michael, Hills, Robert, Pepper, Christopher J., Baird, Duncan M. and Fegan, Christopher D. 2017. Telomere length is an independent prognostic marker in MDS but not in de novo AML. British Journal of Haematology 178 (2) , pp. 240-249.

Law, Philip J., Berndt, Sonja I., Speedy, Helen E., Camp, Nicola J., Sava, Georgina P., Skibola, Christine F., Holroyd, Amy, Joseph, Vijai, Sunter, Nicola J., Nieters, Alexandra, Bea, Silvia, Monnereau, Alain, Martin-Garcia, David, Goldin, Lynn R., Clot, Guillem, Teras, Lauren R., Quintela, Inés, Birmann, Brenda M., Jayne, Sandrine, Cozen, Wendy, Majid, Aneela, Smedby, Karin E., Lan, Qing, Dearden, Claire, Brooks-Wilson, Angela R., Hall, Andrew G., Purdue, Mark P., Mainou-Fowler, Tryfonia, Vajdic, Claire M., Jackson, Graham H., Cocco, Pierluigi, Marr, Helen, Zhang, Yawei, Zheng, Tongzhang, Giles, Graham G., Lawrence, Charles, Call, Timothy G., Liebow, Mark, Melbye, Mads, Glimelius, Bengt, Mansouri, Larry, Glenn, Martha, Curtin, Karen, Diver, W. Ryan, Link, Brian K., Conde, Lucia, Bracci, Paige M., Holly, Elizabeth A., Jackson, Rebecca D., Tinker, Lesley F., Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Maynadie, Marc, McKay, James, Albanes, Demetrius, Weinstein, Stephanie, Wang, Zhaoming, Caporaso, Neil E., Morton, Lindsay M., Severson, Richard K., Riboli, Elio, Vineis, Paolo, Vermeulen, Roel C. H., Southey, Melissa C., Milne, Roger L., Clavel, Jacqueline, Topka, Sabine, Spinelli, John J., Kraft, Peter, Ennas, Maria Grazia, Summerfield, Geoffrey, Ferri, Giovanni M., Harris, Robert J., Miligi, Lucia, Pettitt, Andrew R., North, Kari E., Allsup, David J., Fraumeni, Joseph F., Bailey, James R., Offit, Kenneth, Pratt, Guy, Hjalgrim, Henrik, Pepper, Chris, Chanock, Stephen J., Fegan, Chris, Rosenquist, Richard, de Sanjose, Silvia, Carracedo, Angel, Dyer, Martin J. S., Catovsky, Daniel, Campo, Elias, Cerhan, James R., Allan, James M., Rothman, Nathanial, Houlston, Richard and Slager, Susan 2017. Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. Nature Communications 8 , 14175. 10.1038/ncomms14175

Law, Philip J., Sud, Amit, Mitchell, Jonathan S., Henrion, Marc, Orlando, Giulia, Lenive, Oleg, Broderick, Peter, Speedy, Helen E., Johnson, David C., Kaiser, Martin, Weinhold, Niels, Cooke, Rosie, Sunter, Nicola J., Jackson, Graham H., Summerfield, Geoffrey, Harris, Robert J., Pettitt, Andrew R., Allsup, David J., Carmichael, Jonathan, Bailey, James R., Pratt, Guy, Rahman, Thahira, Pepper, Chris, Fegan, Chris, von Strandmann, Elke Pogge, Engert, Andreas, Försti, Asta, Chen, Bowang, Filho, Miguel Inacio da Silva, Thomsen, Hauke, Hoffmann, Per, Noethen, Markus M., Eisele, Lewin, Jöckel, Karl-Heinz, Allan, James M., Swerdlow, Anthony J., Goldschmidt, Hartmut, Catovsky, Daniel, Morgan, Gareth J., Hemminki, Kari and Houlston, Richard S. 2017. Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. Scientific Reports 7 , 41071. 10.1038/srep41071

Pepper, Christopher John, Tu, Henry, Morrill, Paul, Garcia-Rates, Sara, Fegan, Christopher and Greenfield, Susan 2017. Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor. Oncotarget 10.18632/oncotarget.14545

Pasikowska, Marta, Walsby, Elisabeth, Apollonio, Bendetta, Cuthill, Kirsty, Phillips, Elizabeth, Coulter, Eve, Longhi, Maria Serena, Ma, Yun, Yallop, Deborah, Barber, Linda D., Patten, Piers, Fegan, Chris, Ramsay, Alan G., Pepper, Chris, Devereux, Stephen and Buggins, Andrea G. S. 2016. Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration. Blood 128 (4) , pp. 563-573. 10.1182/blood-2016-01-683128

Parry, Helen Marie, Damery, Sarah, Hudson, Christopher, Maurer, Matthew J., Cerhan, James R., Pachnio, Annette, Begum, Jusnara, Slager, Susan L., Fegan, Christopher Daniel, Man, Stephen, Pepper, Christopher John, Shanafelt, Tait D., Pratt, Guy and Moss, Paul A. H. 2016. Cytomegalovirus infection does not impact on survival or time to first treatment in patients with Chronic Lymphocytic Leukaemia. American Journal of Hematology 91 (8) , pp. 776-781. 10.1002/ajh.24403

Nichols, Eva-Marie, Jones, Rachel, Watson, Rachael, Pepper, Christopher John, Fegan, Christopher Daniel and Marchbank, Kevin 2015. A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL. Oncotarget 6 (32) , pp. 32669-32680. 10.18632/oncotarget.5404

Sava, G. P., Speedy, H. E., Di Bernardo, M. C., Dyer, M. J. S., Holroyd, A., Sunter, N. J., Marr, H., Mansouri, L., Deaglio, S., Karabon, L., Frydecka, I., Jamroziak, K., Woszczyk, D., Juliusson, G., Smedby, K. E., Jayne, S., Majid, A., Wang, Y., Dearden, C., Hall, A. G., Mainou-Fowler, T., Jackson, G. H., Summerfield, G., Harris, R. J., Pettitt, A. R., Allsup, D. J., Bailey, J. R., Pratt, G., Pepper, C., Fegan, C., Rosenquist, R., Catovsky, D., Allan, J. M. and Houlston, R. S. 2015. Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk. Leukemia 29 , pp. 748-751. 10.1038/leu.2014.311

Pepper, C., Buggins, A. G.S., Jones, C. H., Walsby, E. J., Forconi, F., Pratt, G., Devereux, S., Stevenson, F. and Fegan, C. 2015. Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition. Leukemia 29 , pp. 744-747. 10.1038/leu.2014.308

Reid, Reiss, Redman, James Edward, Rizkallah, Pierre, Fegan, Christopher Daniel, Pepper, Christopher John and Man, Stephen Tzekwung 2015. CD8+ T-cell recognition of a synthetic epitope formed by t-butyl modification. Immunology 144 (3) , pp. 495-505. 10.1111/imm.12398

Fegan, Christopher Daniel and Pepper, Christopher John 2015. Understanding cancer cell survival is key to patient survival. The Lancet Oncology 16 (2) , pp. 122-124. 10.1016/S1470-2045(15)70003-3

Lin, Thet Thet, Norris, Kevin, Heppel, Nicole H., Pratt, Guy, Allan, James M., Allsup, David J., Bailey, James, Cawkwell, Lynn, Hills, Robert, Grimstead, Julia W., Jones, Rhiannon E., Britt-Compton, Bethan, Fegan, Christopher, Baird, Duncan Matrin and Pepper, Christopher 2014. Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease. British Journal of Haematology 167 (2) , pp. 214-223. 10.1111/bjh.13023

Walsby, Elisabeth, Buggins, Andrea, Devereux, Stephen, Jones, Ceri, Pratt, Guy, Brennan, Paul, Fegan, Christopher and Pepper, Christopher 2014. Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia. Blood 123 (23) , pp. 3607-3617. 10.1182/blood-2013-12-544569

Bulian, Pietro, Shanafelt, Tait D., Fegan, Chris, Zucchetto, Antonella, Cro, Lilla, Nuckel, Holger, Baldini, Luca, Kurtova, Antonia V., Ferrajoli, Alessandra, Burger, Jan A., Gaidano, Gianluca, Del Poeta, Giovanni, Pepper, Chris, Rossi, Davide and Gattei, Valter 2014. CD49d is the strongest flow cytometry-based predictor of overall survival in chronic lymphocytic leukemia. Journal of Clinical Oncology 32 (9) , pp. 897-904. 10.1200/JCO.2013.50.8515

Pepper, Christopher John, Baird, Duncan Martin and Fegan, Christopher Daniel 2014. Telomere analysis to predict chronic lymphocytic leukemia outcome: a STELA test to change clinical practice? Expert Review of Hematology 7 (6) , pp. 701-703. 10.1586/17474086.2014.969705

Alsagaby, Suliman A., Khanna, Sanjay, Hart, Keith, Pratt, Guy, Fegan, Christopher, Pepper, Christopher, Brewis, Ian and Brennan, Paul 2014. Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia. Journal of Proteome Research 13 (11) , pp. 5051-5062. 10.1021/pr5002803

Wong, Ryan Francis, Pepper, Christopher John, Brennan, Paul, Nagorsen, Dirk, Man, Stephen Tzekwung and Fegan, Christopher Daniel 2013. Blinatumomab induces autologous T cell killing of chronic lymphocytic leukemia cells. Haematologica 98 (12) , pp. 1930-1938. 10.3324/haematol.2012.082248

Groves, M., Johnson, Charlotte, James, J., Prescott, A., Cunningham, J., Haydock, S., Pepper, Christopher John, Fegan, Christopher Daniel, Pirrie, L., Westwood, N., Coates, P., Ganley, I. and Tauro, S. 2013. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia. British Journal of Cancer 109 (9) , pp. 2434-2444. 10.1038/bjc.2013.601

Chubb, D., Weinhold, N., Broderick, P., Chen, B., Johnson, D., Försti, A., Vijayakrishnan, J., Migliorini, G., Dobbins, S., Holroyd, A., Hose, D., Walker, B., Davies, F., Gregory, W., Jackson, G., Irving, J., Pratt, G., Fegan, Christopher Daniel, Fenton, J., Neben, K., Hoffmann, P., Nöthen, M., Mühleisen, T., Eisele, L., Ross, F., Straka, C., Einsele, H., Langer, C., Dörner, E., Allan, J., Jauch, A., Morgan, G., Hemminki, K., Houlston, R. and Goldschmidt, H. 2013. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. Nature Genetics 45 (10) , pp. 1221-1225. 10.1038/ng.2733

Walsby, Elisabeth Jane, Pearce, Laurence, Burnett, Alan Kenneth, Fegan, Christopher Daniel and Pepper, Christopher John 2012. The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells. Oncotarget 3 (5) , pp. 525-534.

Watkins, Catherine Louise, Sayers, Edward John, Allender, Christopher John, Barrow, David Anthony, Fegan, Christopher Daniel, Brennan, Paul and Jones, Arwyn Tomos 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19 (12) , pp. 2124-2132. 10.1038/mt.2011.175

Pourgheysari, Batoul, Bruton, Rachel, Parry, Helen, Billingham, Lucinda, Fegan, Christopher Daniel, Murray, Jim and Moss, Paul 2010. The number of cytomegalovirus-specific CD4+ T cells is markedly expanded in patients with B-cell chronic lymphocytic leukemia and determines the total CD4+ T-cell repertoire. Blood 116 (16) , pp. 2968-2974. 10.1182/blood-2009-12-257147

Crowther-Swanepoel, Dalemari, Broderick, Peter, Di Bernardo, Maria Chiara, Dobbins, Sara E., Torres, María, Mansouri, Mahmoud, Ruiz-Ponte, Clara, Enjuanes, Anna, Rosenquist, Richard, Carracedo, Angel, Jurlander, Jesper, Campo, Elias, Juliusson, Gunnar, Montserrat, Emilio, Smedby, Karin E., Dyer, Martin J. S., Matutes, Estella, Dearden, Claire, Sunter, Nicola J., Hall, Andrew G., Mainou-Fowler, Tryfonia, Jackson, Graham H., Summerfield, Geoffrey, Harris, Robert J., Pettitt, Andrew R., Allsup, David J., Bailey, James R., Pratt, Guy, Pepper, Christopher John, Fegan, Christopher Daniel, Parker, Anton, Oscier, David, Allan, James M., Catovsky, Daniel and Houlston, Richard S. 2010. Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. Nature Genetics 42 (2) , pp. 132-136. 10.1038/ng.510

Pepper, Christopher John, Ward, R., Lin, Thet Thet, Brennan, Paul, Starczynski, J., Musson, M., Rowntree, Claire, Bentley, P., Mills, K., Pratt, G. and Fegan, Christopher Daniel 2007. Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin. Leukemia 21 (4) , pp. 687-696. 10.1038/sj.leu.2404587

Brown, S. A., Davies, S. V., Fegan, Christopher Daniel, West, Robert Raynard, Giddings, J., Whittaker, J. and Burnett, Alan Kenneth 1999. Haemostatic and fibrinolytic responses to bone marrow transplantation. British Journal of Haematology 104 (3) , pp. 468-474. 10.1046/j.1365-2141.1999.01223.x

Brown, S. A., Goringe, A., Fegan, Christopher Daniel, Davies, S. V., Giddings, John Charles, Whittaker, J. A., Burnett, Alan Kenneth and Poynton, Christopher Hilton 1998. Parenteral glutamine protects hepatic function during bone marrow transplantation. Bone Marrow Transplantation 22 (3) , pp. 281-284. 10.1038/sj.bmt.1701321

Brown, S. A., Davies, S. V., Fegan, Christopher Daniel, Ralis, H., Giddings, John Charles, Poynton, Christopher Hilton, Whittaker, J. A. and Burnett, Alan Kenneth 1996. A biphasic haemostatic response during bone marrow transplantation [Abstract]. Blood 88 (10) , p. 1638.

Poynton, Christopher H., Fegan, Christopher Daniel, Al-Sabah, Ali I., Couzens, Stephen, John, S., Hoy, Terence George, White, D. and Burnett, Alan Kenneth 1994. Aberrant durface phenotype in MDS confers a poor-prognosis with more rapid development of AML [Abstract]. Blood 84 (10) , A316.

Jackson, S. K., Parton, J., Barnes, Rosemary Ann, Poynton, Christopher H. and Fegan, Christopher Daniel 1993. Effect of IgM-enriched intravenous immunoglobulin (Pentaglobin) on endotoxaemia and anti-endotoxin antibodies in bone marrow transplantation. European Journal of Clinical Investigation 23 (9) , pp. 540-545. 10.1111/j.1365-2362.1993.tb00963.x

Poynton, Christopher H., Jackson, S., Fegan, Christopher Daniel, Barnes, Rosemary Ann and Whittaker, J. A. 1992. Use of IgM enriched intravenous immunoglobulin (Pentaglobin) in bone marrow transplantation. Bone Marrow Transplantation -Basingstoke then London- 9 (6) , pp. 451-457.

This list was generated on Tue Sep 29 04:26:57 2020 BST.

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