![]() | Up a level |
Forbester, Jessica L., Clement, Mathew, Wellington, Dannielle, Yeung, Amy, Dimonte, Sandra, Marsden, Morgan, Chapman, Lucy, Coomber, Eve L., Tolley, Charlotte, Lees, Emily, Hale, Christine, Clare, Simon, Udalova, Irina, Dong, Tao, Dougan, Gordon and Humphreys, Ian R.
2020.
IRF5 promotes influenza-induced inflammatory responses in human iPSC-derived myeloid cells and murine models.
Journal of Virology
94
(9)
, e00121-20.
10.1128/JVI.00121-20
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Smith, S. E., Busse, D. C., Binter, S., Weston, S., Diaz Soria, C., Laksono, B. M., Clare, S., Van Nieuwkoop, S., Van den Hoogen, B. G., Clement, M., Marsden, M., Humphreys, I. R., Marsh, M., de Swart, R. L., Wash, R. S., Tregoning, J. S. and Kellam, P.
2019.
Interferon-induced Transmembrane Protein 1 restricts replication of virus that enter cells via the plasma membrane.
Journal of Virology
93
(6)
, e02003-18.
10.1128/JVI.02003-18
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McLaren, James, Clement, Mathew, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J., Ladell, Kristin, Price, David A. and Humphreys, Ian R.
2019.
IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea.
Journal of Immunology
202
(3)
, pp. 943-955.
10.4049/jimmunol.1701757
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Gimeno Brias, Silvia, Marsden, Morgan, Forbester, Jessica, Clement, Mathew, Brandt, Cordelia, Harcourt, Katherine, Kane, Leanne, Chapman, Lucy, Clare, Simon and Humphreys, Ian R. 2018. Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection. PLoS ONE 13 (5) , e0197596. 10.1371/journal.pone.0197596 |
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Rai, Taranjit Singh, Glass, Mandy, Cole, John J., Rather, Mohammad I., Marsden, Morgan, Neilson, Matthew, Brock, Claire, Humphreys, Ian R., Everett, Roger D. and Adams, Peter D.
2017.
Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity.
Nucleic Acids Research
45
(20)
, pp. 11673-11683.
10.1093/nar/gkx771
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Sowerby, John M., Thomas, David C., Clare, Simon, Espéli, Marion, Guerrero, Jose A., Hoenderdos, Kim, Harcourt, Katherine, Marsden, Morgan, Abdul-Karim, Juneid, Clement, Mathew, Antrobus, Robin, Umrania, Yagnesh, Barton, Philippa R., Flint, Shaun M., Juss, Jatinder K., Condliffe, Alison M., Lyons, Paul A., Humphreys, Ian R., Chilvers, Edwin R., Ouwehand, Willem H., Dougan, Gordon and Smith, Kenneth G. C. 2017. NBEAL2 is required for neutrophil and NK cell function and pathogen defense. Journal of Clinical Investigation 127 (9) , pp. 3521-3526. 10.1172/JCI91684 |
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Stacey, Maria A., Clare, Simon, Clement, Mathew, Marsden, Morgan, Abdul-Karim, Juneid, Kane, Leanne, Harcourt, Katherine, Brandt, Cordelia, Fielding, Ceri A., Smith, Sarah E., Wash, Rachael S., Gimeno Brias, Silvia, Stack, Gabrielle, Notley, George, Cambridge, Emma L., Isherwood, Christopher, Speak, Anneliese O., Johnson, Zoe, Ferlin, Walter, Jones, Simon A., Kellam, Paul and Humphreys, Ian R.
2017.
The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis.
Journal of Clinical Investigation
127
(4)
, pp. 1463-1474.
10.1172/JCI84889
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Clement, Mathew, Marsden, Morgan, Stacey, Maria, Abdul-Karim, Juneid, Gimeno Brias, Silvia, Costa Bento, Diana Filipa, Scurr, Martin, Weaver, Casey, Carlesso, Gianluca, Clare, Simon, Jones, Simon, Godkin, Andrew, Ghazal, Peter, Jones, Gareth W. and Humphreys, Ian
2016.
Cytomegalovirus-specific IL-10-producing CD4+ T cells are governed by type-I IFN-induced IL-27 and promote virus persistence.
Plos Pathogens
12
(12)
, e1006050.
10.1371/journal.ppat.1006050
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Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A., Snelgrove, Robert J., Lacaze, Paul, Jacques, Laura C., Cuff, Simone, Stanton, Richard J., Gallimore, Awen M., Hussell, Tracy, Wilkinson, Gavin W. G., Ghazal, Peter, Taylor, Philip R. and Humphreys, Ian R.
2015.
CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.
PLoS Pathogens
11
(2)
, e1004641.
10.1371/journal.ppat.1004641
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Stacey, Maria A., Marsden, Morgan, Pham N., Tu Anh, Clare, Simon, Dolton, Garry, Stack, Gabrielle, Jones, Emma, Klenerman, Paul, Gallimore, Awen M., Taylor, Philip R., Snelgrove, Robert J., Lawley, Trevor D., Dougan, Gordon, Benedict, Chris A., Jones, Simon A., Wilkinson, Gavin W. G. and Humphreys, Ian R.
2014.
Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.
Cell Host and Microbe
15
(4)
, pp. 471-483.
10.1016/j.chom.2014.03.003
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Humphreys, Ian R., Clement, Mathew, Marsden, Morgan, Ladell, Kristin Ingrid, McLaren, James Edward, Smart, Kathryn, Hindley, James Philip, Bridgeman, Hayley, van den Berg, Hugo A., Price, David, Ager, Ann, Wooldridge, Linda, Godkin, Andrew James and Gallimore, Awen Myfanwy 2012. Avidity of influenza-specific memory CD8+T-cell populations decays over time compromising antiviral immunity. European Journal of Immunology 42 (12) , pp. 3235-3242. 10.1002/eji.201242575 |
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Twohig, Jason Peter, Marsden, Morgan, Cuff, Simone, Ferdinand, John R., Gallimore, Awen Myfanwy, Perks, William Victor, Al-Shamkhani, Aymen, Humphreys, Ian R. and Wang, Edward Chung Yern 2012. The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity. The FASEB Journal 26 (8) , pp. 3575-3586. 10.1096/fj.11-200618 |
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Stacey, Maria A., Marsden, Morgan, Wang, Edward Chung Yern, Wilkinson, Gavin William Grahame and Humphreys, Ian R. 2011. IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection. The Journal of Immunology 187 (6) , pp. 2944-2952. 10.4049/jimmunol.1101021 |
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