ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Number of items: 18.
Nödling, Alexander, Mills, Emily M., Li, Xuefei, Cardella, Davide, Sayers, Edward J., Wu, Shih-Hsiung, Jones, Arwyn T., Luk, Louis Y. P. and Tsai, Yu-Hsuan
2020.
Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes.
Chemical Communications
56
(34)
, pp. 4672-4675.
10.1039/C9CC07931A
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Wymant, Jennifer Mary, Sayers, Edward John, Muir, Duncan and Jones, Arwyn Tomos
2020.
Strategic trastuzumab mediated crosslinking driving concomitant HER2 and HER3 endocytosis and degradation in breast cancer.
Journal of Cancer
11
(11)
, pp. 3288-3302.
10.7150/jca.32470
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Giannakopoulou, Naya, Williams, Joseph B., Moody, Paul R., Sayers, Edward J., Magnusson, Johannes P., Pope, Iestyn, Payne, Lukas, Alexander, Cameron, Jones, Arwyn T., Langbein, Wolfgang, Watson, Peter and Borri, Paola
2020.
Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells.
Nanoscale
12
(7)
, pp. 4622-4635.
10.1039/C9NR08512B
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Eissa, N.G., Sayers, E.J., Birch, D., Patel, S.G., Tsai, Y.-H., Nielsen, H. Mørck and Jones, Arwyn
2020.
EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide.
Biochemical Journal
477
(1)
, pp. 45-60.
10.1042/BCJ20190452
Item availability restricted. |
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| Sayers, E.J., Peel, S.E., Schantz, A., England, R.M., Beano, M., Bates, S.M., Desai, A.S., Puri, S., Ashford, M.B. and Jones, A.T. 2019. Endocytic profiling of cancer cell models reveals critical factors influencing lipid nanoparticle mediated mRNA delivery and protein expression. Molecular Therapy 27 (11) , pp. 1950-1962. 10.1016/j.ymthe.2019.07.018 |
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| Woods, Ben, Dollerer, Daniel, Aikman, Brech, Wenzel, Margot, Sayers, Edward J., Kühn, Fritz E., Jones, Arwyn T. and Casini, Angela 2019. Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells. Journal of Inorganic Biochemistry 199 , 110781. 10.1016/j.jinorgbio.2019.110781 |
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Lorenzer, Cornelia, Streußnig, Sonja, Tot, Emilia, Winkler, Anna-Maria, Merten, Hannes, Brandl, Fabian, Sayers, Edward J., Watson, Peter, Jones, Arwyn T., Zangemeister-Wittke, Uwe, Plückthun, Andreas and Winkler, Johannes
2019.
Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing.
European Journal of Pharmaceutics and Biopharmaceutics
141
, pp. 37-50.
10.1016/j.ejpb.2019.05.015
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He, L., Sayers, E. J., Watson, P. and Jones, A. T.
2018.
Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates.
Scientific Reports
8
(1)
, 7318.
10.1038/s41598-018-25600-8
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Sayers, Edward J., Magnusson, Johannes P., Moody, Paul R., Mastrotto, Francesca, Conte, Claudia, Brazzale, Chiara, Borri, Paola, Caliceti, Paolo, Watson, Peter, Mantovani, Giuseppe, Aylott, Jonathan, Salmaso, Stefano, Jones, Arwyn T and Alexander, Cameron
2018.
Switching of macromolecular ligand display by thermoresponsive polymers mediates endocytosis of multi-conjugate nanoparticles.
Bioconjugate Chemistry
29
(4)
, pp. 1030-1046.
10.1021/acs.bioconjchem.7b00704
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| Roberts-Dalton, H. D., Cocks, A., Falcon-Perez, J. M., Sayers, E. J., Webber, J. P., Watson, P., Clayton, A. and Jones, A. T. 2017. Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic. Nanoscale 9 (36) , pp. 13693-13706. 10.1039/C7NR04128D |
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| Wymant, Jennifer, Moody, P., Sayers, Edward and Jones, Arwyn Tomos 2017. Poster 433: Receptor-antibody clustering induced endocytosis of HER2 has therapeutic potential in breast cancer. Presented at: EACR-AACR-SIC Special Conference 2017: The Challenges of Optimising Immuno and Targeted Therapies From Cancer Biology to the Clinic, Florence, Italy, 24-27 June 2017. |
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Moody, Paul R., Sayers, Edward J., Magnusson, Johannes P., Alexander, Cameron, Borri, Paola, Watson, Peter and Jones, Arwyn T.
2015.
Receptor crosslinking: a general method to trigger internalization and lysosomal targeting of therapeutic receptor: ligand complexes.
Molecular Therapy
23
(12)
, pp. 1888-1898.
10.1038/mt.2015.178
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| Bahnsen, Jesper Soborg, Franzyk, Henrik, Sayers, Edward John and Jones, Arwyn Tomos 2015. Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections. Pharmaceutical Research 32 (5) , pp. 1546-1556. 10.1007/s11095-014-1550-9 |
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Sayers, Edward John, Cleal, Kez, Eissa, Noura Gamal, Watson, Peter Duncan and Jones, Arwyn Tomos
2014.
Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides.
Journal of Controlled Release
195
, pp. 55-62.
10.1016/j.jconrel.2014.07.055
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| Jones, Arwyn Tomos and Sayers, Edward John 2012. Cell entry of cell penetrating peptides and tales of tails wagging dogs. Journal of Controlled Release 161 (2) , pp. 582-591. 10.1016/j.jconrel.2012.04.003 |
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Sayers, Edward John
2012.
An encoded microwell array for multi-image analysis of cells.
PhD Thesis,
Cardiff University.
Item availability restricted. |
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| Watkins, Catherine Louise, Sayers, Edward John, Allender, Christopher John, Barrow, David Anthony, Fegan, Christopher Daniel, Brennan, Paul and Jones, Arwyn Tomos 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19 (12) , pp. 2124-2132. 10.1038/mt.2011.175 |
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