Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Current Cardiff authors

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Number of items: 41.

Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K. and Sewell, Andrew K. 2019. TCR-induced alteration of primary MHC peptide anchor residue. European Journal of Immunology 49 (7) , pp. 1052-1066. 10.1002/eji.201948085
file

Angelastro, Antonio, Dawson, William M., Luk, Louis Y. P., Loveridge, E. Joel and Allemann, Rudolf K. 2017. Chemoenzymatic assembly of isotopically labeled folates. Journal of the American Chemical Society 139 (37) , pp. 13047-13054. 10.1021/jacs.7b06358
file

Loveridge, Edric Joel, Jones, Cerith, Bull, Matthew J., Moody, Suzy C., Kahl, Malgorzata W, Khan, Zainab, Neilson, Louis, Tomeva, Marina, Adams, Sarah Elizabeth, Wood, Andrew C., Daniel, Rodriguez-Martin, Pinel, Ingrid, Julian, Parkhill, Mahenthiralingam, Eshwar and Crosby, John 2017. Reclassification of the specialized metabolite producer pseudomonas mesoacidophila ATCC 31433 as a member of the burkholderia cepacia complex. Journal of Bacteriology 199 (13) , e00125-17. 10.1128/JB.00125-17
file

Hughes, Robert L., Johnson, Luke A., Behiry, Enas M., Loveridge, Edric Joel and Allemann, Rudolf Konrad 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56 (15) , pp. 2126-2133. 10.1021/acs.biochem.7b00045
file

Loveridge, Edric Joel, Hroch, Lukas, Hughes, Robert L., Williams, Thomas, Davies, Rhidian L., Angelastro, Antonio, Luk, Louis Yu Pan, Maglia, Giovanni and Allemann, Rudolf Konrad 2017. Reduction of folate by dihydrofolate reductase from thermotoga maritima. Biochemistry 56 (13) , pp. 1879-1886. 10.1021/acs.biochem.6b01268
file

Ruiz-Pernía, J. Javier, Behiry, Enas, Luk, Louis Yu Pan, Loveridge, Edric Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf Konrad 2016. Minimization of dynamic effects in the evolution of dihydrofolate reductase. Chemical Science 7 (5) , pp. 3248-3255. 10.1039/C5SC04209G
file

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2016. Pinpointing dynamic coupling in enzymes for efficient drug design. Future Science OA 2 (1) 10.4155/fsoa.2015.0017
file

Luk, Louis Y. P., Ruiz-Pernía, J. Javier, Adesina, Aduragbemi S., Loveridge, E. Joel, Tuñón, Iñaki, Moliner, Vincent and Allemann, Rudolf K. 2015. Chemical ligation and isotope labeling to locate dynamic effects during catalysis by dihydrofolate reductase. Angewandte Chemie International Edition 54 (31) , pp. 9016-9020. 10.1002/anie.201503968
file

Luk, Louis Yu Pan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2015. Protein motions and dynamic effects in enzyme catalysis. Physical Chemistry Chemical Physics 17 , pp. 30817-30827. 10.1039/C5CP00794A
file

Allemann, Rudolf Konrad, Loveridge, Edric and Luk, Louis Yu Pan 2015. Protein motions, dynamic effects and thermal stability in dihydrofolate reductase from the hyperthermophile thermotoga maritima. In: Olivares-Quiroz, Luis, Guzmán-López, Orlando and Jardón-Valadez, Hector Eduardo eds. Physical Biology of Proteins and Peptides: Theory, Experiment, and Simulation, Springer International Publishing, pp. 99-113. (10.1007/978-3-319-21687-4_6)

Luk, Louis Y. P., Ruiz-Pernia, J. Javier, Dawson, William M., Loveridge, E. Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf K. 2014. Protein isotope effects in dihydrofolate reductase from Geobacillus stearothermophilus show entropic-enthalpic com-pensatory effects on the rate constant. Journal of the American Chemical Society 136 (49) , pp. 17317-17323. 10.1021/ja5102536
file

Moody, Suzy C. and Loveridge, Edric Joel 2014. CYP105-diverse structures, functions and roles in an intriguing family of enzymes in Streptomyces. Journal of Applied Microbiology 117 (6) , pp. 1549-1563. 10.1111/jam.12662
file

Behiry, Enas Mamdouh, Luk, Louis Yu Pan, Matthews, Stella M., Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Role of the occluded conformation in bacterial dihydrofolate reductases. Biochemistry 53 (29) , pp. 4761-4768. 10.1021/bi500507v
file

Behiry, Enas Mamdouh, Evans, Rhiannon Mari, Guo, Jian Nan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Loop Interactions during Catalysis by Dihydrofolate Reductase from Moritella profunda. Biochemistry 53 (29) , pp. 4769-4774. 10.1021/bi500508z
file

Luk, Louis Y. P., Loveridge, E. Joel and Allemann, Rudolf K. 2014. Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases. Journal of the American Chemical Society 136 (19) , pp. 6862-6865. 10.1021/ja502673h
file

Guo, Jian Nan, Luk, Louis Yu Pan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Thermal adaptation of dihydrofolate reductase from the moderate thermophile geobacillus stearothermophilus. Biochemistry 53 (17) , pp. 2855-2863. 10.1021/bi500238q
file

Hull, Claire M, Loveridge, Edric Joel, Rolley, Nicola J, Donnison, Iain S, Kelly, Steven L and Kelly, Diane E 2014. Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock. Biotechnology for Biofuels 7 (1) , 133. 10.1186/s13068-014-0133-7
file

Hull, Claire M, Loveridge, Edric Joel, Donnison, Iain S, Kelly, Diane E and Kelly, Steven L 2014. Co-production of bioethanol and probiotic yeast biomass from agricultural feedstock: application of the rural biorefinery concept. AMB Express 4 (1) , 64. 10.1186/s13568-014-0064-5
file

Ruiz-Pernia, J. Javier, Luk, Louis Yu Pan, Garcia-Meseguer, Rafael, Martí, Sergio, Loveridge, Edric Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf Konrad 2013. Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society 135 (49) , pp. 18689-18696. 10.1021/ja410519h
file

Luk, Louis Yu Pan, Ruiz-Pernia, J. Javier, Dawson, William Michael, Roca, Maite, Loveridge, Edric Joel, Glowacki, David R., Harvey, Jeremy N., Mulholland, Adrian J., Tunon, Inaki, Moliner, Vicent and Allemann, Rudolf Konrad 2013. Unraveling the role of protein dynamics in dihydrofolate reductase catalysis. Proceedings of the National Academy of Sciences of the United States of America 110 (41) , pp. 16344-16349. 10.1073/pnas.1312437110

Guo, Jiannan, Loveridge, Edric Joel, Luk, Louis Yu Pan and Allemann, Rudolf Konrad 2013. Effect of dimerization on dihydrofolate reductase catalysis. Biochemistry 52 (22) , pp. 3881-3887. 10.1021/bi4005073

Loveridge, Edric Joel, Matthews, Stella M., Williams, Christopher, Whittaker, Sara B.-M., Günther, Ulrich L., Evans, Rhiannon M., Dawson, William Michael, Crump, Matthew P. and Allemann, Rudolf Konrad 2013. Aliphatic 1H, 13C and 15N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP+ and folate. Biomolecular NMR Assignments 7 (1) , pp. 61-64. 10.1007/s12104-012-9378-x

Wysoczanski, Piotr, Mart, Robert J., Loveridge, Edric Joel, Williams, Christopher, Whittaker, Sara B.-M., Crump, Matthew P. and Allemann, Rudolf Konrad 2013. 1H, 13C and 15N chemical shift assignments of unliganded Bcl-xL and its complex with a photoresponsive Bak-derived peptide. Biomolecular NMR Assignments 7 (2) , pp. 187-191. 10.1007/s12104-012-9407-9

Wysoczanski, Piotr, Mart, Robert J., Loveridge, Edric Joel, Williams, Christopher, Whittaker, Sara B.-M., Crump, Matthew P. and Allemann, Rudolf Konrad 2012. NMR solution structure of a photoswitchable apoptosis activating Bak peptide bound to Bcl-xL. Journal of the American Chemical Society 134 (18) , pp. 7644-7647. 10.1021/ja302390a

Loveridge, Edric Joel, Behiry, Enas Mamdouh, Guo, Jian Nan and Allemann, Rudolf Konrad 2012. Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis. Nature Chemistry 4 (4) , pp. 292-297. 10.1038/nchem.1296

Loveridge, Edric Joel, Tey, Lai-Hock, Behiry, Enas Mamdouh, Dawson, William Michael, Evans, Rhiannon Mari, Whittaker, Sara B.-M., Günther, Ulrich L., Williams, Christopher, Crump, Matthew P. and Allemann, Rudolf Konrad 2011. The role of large-scale motions in catalysis by dihydrofolate reductase. Journal of the American Chemical Society 133 (50) , pp. 20561-20570. 10.1021/ja208844j
file

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2011. Effect of pH on Hydride Transfer by Escherichia coli Dihydrofolate Reductase. ChemBioChem 12 (8) , pp. 1258-1262. 10.1002/cbic.201000794

Loveridge, Edric Joel, Dawson, William Michael, Evans, Rhiannon Mari, Sobolewska, Anna and Allemann, Rudolf Konrad 2011. Reduced Susceptibility of Moritella profunda Dihydrofolate Reductase to Trimethoprim is Not Due to Glutamate 28. The Protein Journal 30 (8) , pp. 546-548. 10.1007/s10930-011-9361-x

Tey, Lai-Hock, Loveridge, Edric Joel, Swanwick, Richard, Flitsch, Sabine L. and Allemann, Rudolf Konrad 2010. Highly site-selective stability increases by glycosylation of dihydrofolate reductase. FEBS Journal 277 (9) , pp. 2171-2179. 10.1111/j.1742-4658.2010.07634.x

Loveridge, Edric Joel, Tey, Lai-Hock and Allemann, Rudolf Konrad 2010. Solvent effects on catalysis by Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society 132 (3) , pp. 1137-1143. 10.1021/ja909353c

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2010. The Temperature Dependence of the Kinetic Isotope Effects of Dihydrofolate Reductase from Thermotoga maritima Is Influenced by Intersubunit Interactions. Biochemistry 49 (25) , pp. 5390-5396. 10.1021/bi100761x

Evans, Rhiannon Mari, Behiry, Enas Mamdouh, Tey, Lai-Hock, Guo, Jiannan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2010. Catalysis by Dihydrofolate Reductase from the Psychropiezophile Moritella profunda. ChemBioChem 11 (14) , pp. 2010-2017. 10.1002/cbic.201000341

Loveridge, Edric Joel, Behiry, Enas Mamdouh, Swanwick, Richard S. and Allemann, Rudolf Konrad 2009. Different reaction mechanisms for mesophilic and thermophilic dihydrofolate reductases. Journal of the American Chemical Society 131 (20) , pp. 6926-6927. 10.1021/ja901441k

Hay, Sam, Evans, Rhiannon Mari, Levy, Colin, Loveridge, Edric Joel, Wang, Xi, Leys, David, Allemann, Rudolf Konrad and Scrutton, Nigel S. 2009. Are the Catalytic Properties of Enzymes from Piezophilic Organisms Pressure Adapted? ChemBioChem 10 (14) , pp. 2348-2353. 10.1002/cbic.200900367

Allemann, Rudolf Konrad, Evans, Rhiannon Mari and Loveridge, Edric Joel 2009. Probing coupled motions in enzymatic hydrogen tunnelling reactions. Biochemical Society Transactions 37 , pp. 349-353. 10.1042/BST0370349

Loveridge, Edric Joel, Rodriguez, R. J., Swanwick, Richard S. and Allemann, Rudolf Konrad 2009. Effect of Dimerization on the Stability and Catalytic Activity of Dihydrofolate Reductase from the Hyperthermophile Thermotoga maritima. Biochemistry 48 (25) , pp. 5922-5933. 10.1021/bi900411a

Loveridge, Edric Joel, Maglia, Giovanni and Allemann, Rudolf Konrad 2009. The Role of Arginine 28 in Catalysis by Dihydrofolate Reductase from the HyperthermophileThermotoga maritima. ChemBioChem 10 (16) , pp. 2624-2627. 10.1002/cbic.200900465

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2009. Direct methods for the analysis of quantum-mechanical tunnelling: dihydrofolate reductase. In: Allemann, Rudolf Konrad and Scrutton, N. S. eds. Quantum Tunnelling in Enzyme-Catalysed Reactions, London: RSC Publishing, pp. 179-198. (10.1039/9781847559975-00179)

Loveridge, Edric Joel, Evans, R. M. and Allemann, Rudolf Konrad 2008. Solvent Effects on Environmentally Coupled Hydrogen Tunnelling During Catalysis by Dihydrofolate Reductase from Thermotoga maritima. Chemistry-a European Journal 14 (34) , pp. 10782-10788. 10.1002/chem.200801804

Kneissl, Sabine, Loveridge, Edric Joel, Williams, Christopher, Crump, Matthew P. and Allemann, Rudolf Konrad 2008. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL. ChemBioChem 9 (18) , pp. 3046-3054. 10.1002/cbic.200800502

Simm, Alan M., Loveridge, Edric Joel, Crosby, John, Avison, Matthew B., Walsh, Timothy Rutland and Bennett, Peter M. 2005. Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases. Biochemical Journal 387 (3) , pp. 585-590. 10.1042/BJ20041542

This list was generated on Sun Sep 27 06:07:46 2020 BST.


Maintained by Cardiff University Information Services