Watts, Katie, Wills, Christopher, Madi, Ayman, Palles, Claire, Maughan, Timothy S., Kaplan, Richard, Al-Tassan, Nada A., Kerr, Rachel, Kerr, David J., Houlston, Richard S., Escott-Price, Valentina and Cheadle, Jeremy P. 2022. Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome. International Journal of Cancer 10.1002/ijc.34046 |
Adams, Richard, Wilson, Richard, Brown, Louise and Maughan, Timothy 2022. Reply to A. Kurreck et al and M.S. Copur et al. Journal of Clinical Oncology 40 (11) , pp. 1263-1264. 10.1200/JCO.21.02806 |
Papamichael, Demetris, Lopes, Guilherme S., Olswold, Curt L., Douillard, Jean-Yves, Adams, Richard A., Maughan, Timothy S., Van Cutsem, Eric, Venook, Alan P., Lenz, Heinz-Josef, Heinemann, Volker, Kaplan, Richard, Bokemeyer, Carsten, Chibaudel, Benoist, Grothey, Axel, Yoshino, Takayuki, Zalcberg, John, De Gramont, Aimery and Shi, Qian 2022. Efficacy of anti-epidermal growth factor receptor agents in patients with RAS wild-type metastatic colorectal cancer ≥ 70 years. European Journal of Cancer 163 , pp. 1-15. 10.1016/j.ejca.2021.12.007 |
Cornish, Alex J., Law, Philip J., Timofeeva, Maria, Palin, Kimmo, Farrington, Susan M., Palles, Claire, Jenkins, Mark A., Casey, Graham, Brenner, Hermann, Chang-Claude, Jenny, Hoffmeister, Michael, Kirac, Iva, Maughan, Tim, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P., Aaltonen, Lauri A., Tomlinson, Ian, Dunlop, Malcolm G. and Houlston, Richard S. 2020. Modifiable pathways for colorectal cancer: a mendelian randomisation analysis. Lancet Gastroenterology and Hepatology 5 (1) , pp. 55-62. 10.1016/S2468-1253(19)30294-8 |
Summers, Matthew G., Maughan, Timothy S., Kaplan, Richard, Law, Philip J., Houlston, Richard S., Escott-Price, Valentina and Cheadle, Jeremy P. 2020. Comprehensive analysis of colorectal cancer-risk loci and survival outcome: a prognostic role for CDH1 variants. European Journal Of Cancer 124 , pp. 56-63. 10.1016/j.ejca.2019.09.024 |
West, Hannah, Coffey, Michelle, Wagner, Michael J., McLeod, Howard L., Colley, James P., Adams, Richard A., Fleck, Oliver, Maughan, Timothy S., Fisher, David, Kaplan, Richard S., Harris, Rebecca and Cheadle, Jeremy P. 2018. Role for nucleotide excision repair gene variants in oxaliplatin-induced peripheral neuropathy. JCO Precision Oncology 2 , pp. 1-18. 10.1200/PO.18.00090 |
Madi, Ayman, Fisher, David, Maughan, Timothy S., Colley, James P., Meade, Angela M., Maynard, Julie, Humphreys, Vikki, Wasan, Harpreet, Adams, Richard A., Idziaszczyk, Shelley, Harris, Rebecca, Kaplan, Richard S. and Cheadle, Jeremy P. 2018. Pharmacogenetic analyses of 2,183 patients with advanced colorectal cancer; Potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy. European Journal of Cancer 102 , pp. 31-39. 10.1016/j.ejca.2018.07.009 |
Sjoquist, Katrin M., Renfro, Lindsay A., Simes, R. John, Tebbutt, Niall C., Clarke, Stephen, Seymour, Matthew T., Adams, Richard, Maughan, Timothy S., Saltz, Leonard, Goldberg, Richard M., Schmoll, Hans-Joachim, Van Cutsem, Eric, Douillard, Jean-Yves, Hoff, Paulo M., Hecht, Joel Randolph, Tournigand, Christophe, Punt, Cornelis J. A., Koopman, Miriam, Hurwitz, Herbert, Heinemann, Volker, Falcone, Alfredo, Porschen, Rainer, Fuchs, Charles, Diaz-Rubio, Eduardo, Aranda, Enrique, Bokemeyer, Carsten, Souglakos, Ioannis, Kabbinavar, Fairooz F., Chibaudel, Benoist, Meyers, Jeffrey P., Sargent, Daniel J., de Gramont, Aimery and Zalcberg, John R. 2018. Personalizing survival predictions in advanced colorectal cancer: the ARCAD nomogram project. JNCI: Journal of the National Cancer Institute 110 (6) , pp. 638-648. 10.1093/jnci/djx253 |
Summers, Matthew, Smith, Chris, Maughan, Timothy, Kaplan, Rick, Escott-Price, Valentina and Cheadle, Jeremy Peter 2017. BRAF and NRAS locus-specific variants have different outcomes on survival to colorectal cancer. Clinical Cancer Research 23 (11) , pp. 2742-2749. 10.1158/1078-0432.CCR-16-1541 |
Crosby, Tom, Hurt, Christopher, Falk, S, Gollins, S, Staffurth, John, Ray, Ruby, Bridgewater, J A, Geh, J I, Cunningham, D, Blazeby, J, Roy, R, Maughan, Timothy, Griffiths, Gwyn and Mukherjee, Saptarshi 2017. Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/? cetuximab in oesophageal cancer. British Journal of Cancer 116 (6) , pp. 709-716. 10.1038/bjc.2017.21 |
Jarvis, David, Mitchell, Jonathan S., Law, Philip J., Palin, Kimmo, Tuupanen, Sari, Gylfe, Alexandra, Hanninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Kaprio, Jaakko, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Jarvinen, Heikki, Renkonen-Sinisalo, Laura, Lepisto, Anna, Bohm, Jan, Mecklin, Jukka-Pekka, Al-Tassan, Nada A., Palles, Claire, Martin, Lynn, Barclay, Ella, Farrington, Susan M., Mimofeeva, Maria N., Meyer, Brian ., Wakil, Salma M., Campbell, Harry, Smith, Christopher G., Idziaszczyk, Shelley, Maughan, Timothy, Kaplan, Richard, Kerr, Rachel, Buchanan, Daniel D., Win, Aung K., Hopper, John L., Jenkins, Mark A., Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Taipale, Jussi, Aaltonen, Lauri A., Cheadle, Jeremy, Dunlop, Malcolm G., Tomlinson, Ian P. and Houlston, Richard S. 2016. Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer. British Journal of Cancer 115 , pp. 266-272. 10.1038/bjc.2016.188 |
Orlando, Giulia, Law, Philip J., Palin, Kimmo, Tuupanen, Sari, Gylfe, Alexandra, Hänninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Kaprio, Jaakko, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Järvinen, Heikki, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Al-Tassan, Nada A., Palles, Claire, Martin, Lynn, Barclay, Ella, Tenesa, Albert, Farrington, Susan, Timofeeva, Maria N., Meyer, Brian F., Wakil, Salma M., Campbell, Harry, Smith, Christopher G., Idziaszczyk, Shelley, Maughan, Timothy Stanley, Kaplan, Richard, Kerr, Rachel, Kerr, David, Buchanan, Daniel D., Ko Win, Aung, Hopper, John, Jenkins, Mark, Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Taipale, Jussi, Cheadle, Jeremy Peter, Dunlop, Malcolm G., Tomlinson, Ian P., Aaltonen, Lauri A. and Houlston, Richard S. 2016. Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. Human Molecular Genetics 25 (11) , pp. 2349-2359. 10.1093/hmg/ddw087 |
Hurt, Chris Nicholas, Mukherjee, Somnath, Bridgewater, John, Falk, Stephen, Crosby, Tom, McDonald, Alec, Joseph, George, Staffurth, John Nicholas, Abrams, Ross A., Blazeby, Jane M., Bridges, Sarah, Dutton, Peter, Griffiths, Gareth, Maughan, Timothy and Johnson, Colin 2015. Health-related quality of life in SCALOP, a randomized Phase 2 trial comparing chemoradiation therapy regimens in locally advanced pancreatic cancer. International Journal of Radiation Oncology Biology Physics 93 (4) , pp. 810-818. |
Richman, Susan D., Adams, Richard Alexander, Quirke, Phil, Butler, Rachel, Hemmings, Gemma, Chambers, Phil, Roberts, Helen, James, Michelle D., Wozniak, Sue, Bathia, Riya, Pugh, Cheryl, Maughan, Timothy Stanley and Jasani, Bharat 2015. Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial. Journal of Clinical Pathology 69 (1) , pp. 35-41. 10.1136/jclinpath-2015-203097 |
Smith, Christopher G., Fisher, David, Harris, Rebecca, Maughan, Timothy S., Phipps, Amanda I., Richman, Susan, Seymour, Matthew, Tomlinson, Ian, Rosmarin, Dan, Kerr, David, Chan, Andrew T., Peters, Ulrike, Newcombe, Polly A., Idziaszczyk, Shelley, West, Hannah, Meade, Angela, Kaplan, Richard and Cheadle, Jeremy P. 2015. Analyses of 7,635 patients with colorectal cancer using independent training and validation cohorts show that rs9929218 in CDH1 is a prognostic marker of survival. Clinical Cancer Research 21 (15) , pp. 3453-3461. 10.1158/1078-0432.CCR-14-3136 |
Rees, J., Hurt, Chris Nicholas, Gollins, S., Mukherjee, S., Maughan, Timothy, Falk, S. J., Staffurth, John Nicholas, Ray, Ruby, Bashir Mohamad, Nurul, Geh, J. I., Cunningham, D., Roy, R., Bridgewater, J., Griffiths, G., Nixon, Lisette Sheena, Blazeby, J. M. and Crosby, T. 2015. Patient-reported outcomes during and after definitive chemoradiotherapy for oesophageal cancer. British Journal of Cancer 113 (4) , pp. 603-610. 10.1038/bjc.2015.258 |
Al-Tassan, Nada A., Whiffin, Nicola, Hosking, Fay J., Palles, Claire, Farrington, Susan M., Dobbins, Sara E., Harris, Rebecca, Gorman, Maggie, Tenesa, Albert, Meyer, Brian F., Wakil, Salma M., Kinnersley, Ben, Campbell, Harry, Martin, Lynn, Smith, Christopher G., Idziaszczyk, Shelley Alexis, Barclay, Ella, Maughan, Timothy Stanley, Kaplan, Richard, Kerr, Rachel, Kerr, David, Buchannan, Daniel D., Ko Win, Aung, Hopper, John, Jenkins, Mark, Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Dunlop, Malcolm G., Tomlinson, Ian P., Cheadle, Jeremy Peter and Houlston, Richard S. 2015. A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. Scientific Reports 5 , 10442. 10.1038/srep10442 |
Venderbosch, Sabine, Nagtegaal, Iris D., Maughan, Tim S., Smith, Christopher G., Cheadle, Jeremy P., Fisher, David, Kaplan, Richard, Quirke, Philip, Seymour, Matthew T., Richman, Susan D., Meijer, Gerrit A., Ylstra, Bauke, Heideman, Danielle A. M., de Haan, Anton F. J., Punt, Cornelius J. A. and Koopman, Miriam 2014. Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN, and FOCUS studies. Clinical Cancer Research 20 (20) , pp. 5322-5330. 10.1158/1078-0432.CCR-14-0332 |
Mukherjee, Somnath, Hurt, Chris Nicholas, Dutton, Peter, Bridgewater, John A., Crosby, Thomas, Mcdonald, Alec, Falk, Stephen, Abrams, Ross A., Maughan, Timothy Stanley and Griffiths, Gareth 2014. Impact of gemcitabine (Gem)-or capecitabine (Cape)-based chemoradiation (CRT) on health-relatedquality of life (HRQL) in patients with locally advanced pancreatic cancer (LAPC): Outcomes from the randomized phase II SCALOP trial [Abstract]. Journal of Clinical Oncology 32 (5) , 4126. 10.1200/jco.2014.32.15_suppl.4126 |
Adams, Richard and Maughan, Tim 2014. Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer. Expert Review of Anticancer Therapy 7 (4) , pp. 503-518. 10.1586/14737140.7.4.503 |
Smith, Chris, West, Hannah, Harris, Rebecca, Idziaszczyk, Shelley Alexis, Maughan, Timothy Stanley, Kaplan, Richard, Richman, Susan, Quirke, Philip, Seymour, Matthew, Escott-Price, Valentina, Steinke, Verena, Propping, Peter, Hes, Frederik J., Wijnen, Juul and Cheadle, Jeremy P. 2013. Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis. Journal of the National Cancer Institute 105 (16) , pp. 1249-1253. 10.1093/jnci/djt183 |
Crosby, Thomas David Lewis, Hurt, Chris Nicholas, Falk, Stephen, Gollins, Simon, Mukherjee, Somnath, Staffurth, John Nicholas, Ray, Ruby, Bashir, Nadim, Bridgewater, John A., Geh, J. Ian, Cunningham, David, Blazeby, Jane, Roy, Rajarshi, Maughan, Timothy Stanley and Griffiths, Gareth O. 2013. Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicentre, phase 2/3 randomised trial. The Lancet Oncology 14 (7) , pp. 627-637. 10.1016/S1470-2045(13)70136-0 |
Mukherjee, Somnath, Hurt, Chris Nicholas, Bridgewater, John, Falk, Stephen, Cummins, Sebastian, Wasan, Harpreet, Crosby, Thomas David Lewis, Jephcott, Catherine, Roy, Rajarshi, Radhakrishna, Ganesh, McDonald, Alec, Ray, Ruby, Joseph, George, Staffurth, John Nicholas, Abrams, Ross A., Griffiths, Gareth O. and Maughan, Timothy Stanley 2013. Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial. The Lancet Oncology 14 (4) , pp. 317-326. 10.1016/S1470-2045(13)70021-4 |
Burnet, N. G., Billingham, L. J., Chan, C. S. K., Hall, E., Macdougall, J., Mackay, R. I., Maughan, Timothy Stanley, Nutting, C. M., Staffurth, John Nicholas and Illidge, T. M. 2012. Methodological considerations in the evaluation of radiotherapy technologies [Editorial]. Clinical Oncology 24 (10) , pp. 707-709. 10.1016/j.clon.2012.06.003 |
Vale, Claire L., Tierney, Jayne F., Fisher, David, Adams, Richard Alexander, Kaplan, Richard, Maughan, Timothy Stanley, Parmar, Mahesh K. B. and Meade, Angela M. 2012. Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis. Cancer Treatment Reviews 38 (6) , pp. 618-625. 10.1016/j.ctrv.2011.11.002 |
Dunlop, Malcolm G., Dobbins, Sara E., Farrington, Susan Mary, Jones, Angela M., Palles, Claire, Whiffin, Nicola, Tenesa, Albert, Spain, Sarah, Broderick, Peter, Ooi, Li-Yin, Domingo, Enric, Smillie, Claire, Henrion, Marc, Frampton, Matthew, Martin, Lynn, Grimes, Graeme, Gorman, Maggie, Semple, Colin, Ma, Yusanne P., Barclay, Ella, Prendergast, James, Cazier, Jean-Baptiste, Olver, Bianca, Penegar, Steven, Lubbe, Steven, Chander, Ian, Carvajal-Carmona, Luis G., Ballereau, Stephane, Lloyd, Amy, Vijayakrishnan, Jayaram, Zgaga, Lina, Rudan, Igor, Theodoratou, Evropi, Thomas, Huw, Maher, Eamonn, Evans, Gareth, Walker, Lisa, Halliday, Dorothy, Lucassen, Anneke, Paterson, Joan, Hodgson, Shirley, Homfray, Tessa, Side, Lucy, Izatt, Louise, Donaldson, Alan, Tomkins, Susan, Morrison, Patrick, Brewer, Carole, Henderson, Alex, Davidson, Rosemarie, Murday, Victoria, Cook, Jaqueline, Haites, Neva, Bishop, Timothy, Sheridan, Eamonn, Green, Andrew, Marks, Christopher, Carpenter, Sue, Broughton, Mary, Greenhalge, Lynn, Suri, Mohnish, Starr, John M., Deary, Ian, Kirac, Iva, Kovacevi, Dujo, Aaltonen, Lauri A., Renkonen-Sinisalo, Laura, Mecklin, Jukka-Pekka, Matsuda, Koichi, Nakamura, Yusuke, Okada, Yukinori, Gallinger, Steven, Duggan, David J., Conti, David, Newcomb, Polly, Hopper, John, Jenkins, Mark A., Schumacher, Fredrick, Casey, Graham, Easton, Douglas, Shah, Mitul, Pharoah, Paul, Lindblom, Annika, Liu, Tao, Edler, David, Lenander, Claes, Dalén, Johan, Hjern, Fredrik, Lundqvist, Nils, Lindforss, Ulrik, Påhlman, Lars, Smedh, Kennet, Törnqvist, Anders, Holm, Jörn, Janson, Martin, Andersson, Magnus, Ekelund, Susanne, Olsson, Louise, Smith, Chris, West, Hannah, Cheadle, Jeremy Peter, MacDonald, Graham, Samuel, Leslie M., Ahmad, Athar, Corrie, Philippa, Jodrell, Duncan, Palmer, Cheryl, Wilson, Charles, O'Hagan, Julie, Smith, David, McDermott, Ray, Walshe, Janice, Cassidy, James, McDonald, Alec, Mohammed, Nazia, White, Jeff, Yosef, Hosney, Breathnach, Oscar, Grogan, Liam, Thomas, Robert, Eatock, Martin, Henry, Paul, Houston, Russell, Johnston, Patrick, Wilson, Richard, Geh, Ian, Danwata, Falalu, Hindley, Andrew, Susnerwala, Shabbir, Bradley, Chris, Conn, Andrew, Raine, Anne, Twelves, Chris, Falk, Stephen, Hopkins, Kirstin, Tahir, Saad, Dhadda, Amandeep, Maraveyas, Anthony, Sgouros, Joseph, Teo, Mark, Ahmad, Rizvana, Cleator, Susan, Creak, Antonia, Lowdell, Charles, Riddle, Philippa, Benstead, Kim, Farrugia, David, Reed, Nicholas, Shepherd, Stephen, Levine, Edward, Mullamitha, Saifee, Saunders, Mark, Valle, Juan, Wilson, Gregory, Jones, Adam, Weaver, Andrew, Clark, Peter I., Haylock, Brain, Iqbal, Mussawar I., Myint, Arthur S., Smith, David, Beesley, Sharon, Sevitt, Timothy, Nicoll, Jonathan, Daniel, Francis, Ford, Victoria, Talbot, Toby, Butt, Mohammad, Hamid, Abdel, Mack, Paul, Roy, Raj, Osborne, Richard, McKinna, Fiona, Alsab, Heidar, Basu, Devyanee, Murray, Phillip, Sizer, Bruce, Azam, Faisal A., Neupane, Rekha, Waterston, Ashita, Glaholm, John, Blesing, Claire, Lowndes, Sarah, Medisetti, Aruna, Gaya, Andrew, Leslie, Martin, Maisey, Nicholas, Ross, Paul, Dunn, Grainne, Al-Salihi, Omar, Wasan, Harpreet S., Palmer, Cheryl, Tan, Li Tee, Dent, Jo, Hofmann, Uschi, Joffe, Johnathan K., Sherwin, Elizabeth, Soomal, Rabinder, Chakrabarti, Amitabha, Joseph, Shibu, Van der Voet, Johannes, Wadd, Nicholas J., Wilson, David, Anjarwalia, Salim, Hall, Julia, Hughes, Rob, Polychronis, Andrew, Scarffe, John H., Hill, Mark, James, Rodger D., Shah, Riyaz, Summers, Jeffrey, Hartley, Andrew, Carney, Desmond, McCaffrey, John, Bystricky, Brano, O'Reilly, Seamus, Gupta, Rajnish, Al-Mishlab, Talib, Gidden, Fiona, O'Hara, Richard, Stewart, Jill, Ashford, Richard, Glynne-Jones, Robert, Harrison, Mark, Mawdsley, Suzannah, Barlow, Hilary, Tighe, Mary, Walther, Julie, Neal, Janet, Rees, Charlotte, Bridgewater, John, Karp, Stephen, McGovern, Ursula, Atherton, Philip J., El-deeb, Hany, Macmillan, Craig, Patel, Kinnari, Bessell, Eric Michael, Dickinson, Peter D., Potter, Vanessa, Jephcott, Catherine, McAdam, Karen, Wrigley, Jessica, Osborne, Richard, Muthuramalingam, Sethupathi, O'Callaghan, Anne, Bridgewater, John, Melcher, Lucinda, Braconi, Chiara, Geh, Ju Ian, Palmer, Dan, Narayana, Priya, Steven, Neil, Gaya, Andres, Maisey, Nicholas, Rudman, Sarah, Chakraborti, Prabir, Kelly, Kay, Macgregor, Carol, Whillis, David, Freebairn, Alice, Gildersleve, James, Sharif, Sahid, Astras, George, Hickish, Tamas, Beech, Darren, Ellis, Richard, Kulkarni, Rajendra, Shankland, K., Begent, Richard, Mayer, Astrid, Meyer, Timothy, Strauss, Sandra, Hall, Viriginia, Raj, Sanjay, Chau, Ian, Cunningham, David, Birtle, Alison, Biswas, Ashoke, Susnerwala, Shabbir, Wise, Marcus, Cummins, Sebastian, Essapen, Sharadah, Middleton, Gary, Topham, Claire, Langley, Ruth, McKinna, Fiona, Webb, Andrew, Wilkins, Marie, Iveson, Timothy John, Dhadda, Amandeep, Hamid, Abdel, Askill, Colin, Wagstaff, John, Azzabi, Ashraf, Bateman, Adrian, Prejbisz, Jan, Tsang, David, Ali, Nasim, Jones, Amanda, O'Neill, Paul, Cottrill, Christopher, Propper, David, Lofts, Fiona Jane, Kennedy, James, Anthoney, David A., Cooper, Rachel, Crellin, Adrian, Melcher, Alan, Seymour, Matthew, Baughan, Christopher, Alexander, Emma, Cleator, Susan, Crown, John, Fennelly, David, Adab, Fawzi, Giridharan, Selvaraj, Pedley, Ian, Wright, Kathryn, Bliss, Peter, Cogill, Geoffrey, Lo, Nangi, Toy, Elizabeth, Bridgewater, John, Hochhauser, Daniel, Ledermann, Jonathan, Brewster, A. E., Maughan, Timothy Stanley, Mort, Diana, Mukherjee, Somnath, Dobrowsky, Werner, Calvert, Paula, Leonard, Gregory, Ahmad, Rizvana, Ford, Hugo, Moody, Anne Margeret, Goriah, Sonia, Wilkins, Margeret, Clive, Sally, Dawson, Lesley, McLean, Catriona, Phillips, Hamish Andrew, Gopi, Kakumudi, Tomlinson, Marjorie, Clenton, Susan, Furniss, Debra, Hornbuckle, Joanne, Pledge, Simon, Wadsley, Jonathan, Abbas, Mohammed, Marshall, Ernest, Harper-Wynne, Catherine, Barnes, Anne, Kumar, Satish, Vigneswaran, Vallipuram, Farrugia, David, Webb, Andrew, Gollins, Simon, Falk, Stephen, Genton, M., Sparrow, Geoff, Bale, Catherine, Fuller, C., Mullard, Anna, Stuart, Nicholas, Williams, Rachel, Keane, Maccon, Maughan, Tim, Seymour, Matthew, Wilson, Richard, Wasan, Harpreet, Adams, Richard Alexander, Madi, Ayman, Cassidy, James, Kennedy, James, Hodgkinson, Elizabeth, Rogers, Penny, Pope, Malcolm, Kaplan, Rick, Meade, Angela, Parmar, Mahesh, Kenny, Sarah, Fisher, David, Harper, Lynda, Mitchell, Jena, Nichols, Laura, Sydes, Benjamin, Clement, Louise, Kay, Edward, Courtney, Cheryl, Gallagher, Madalena, Murphy, Claire, Thompson, Lindsay, Beall, Sarah, Hassan, Sharma, Gracie, Richard, Griffiths, Gareth O., Mason, Malcolm David, Parker, Chris, Rudd, Robin, Johnson, Patrick, Whelan, Jeremy, Northover, John, Brown, Julia, Aapro, Matti, Stout, Ronald, Midgley, Rachel, Kerr, David J., Campbell, Harry, Tomlinson, Ian P. and Houlston, Richard S. 2012. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk [Letter]. Nature Genetics 44 (7) , pp. 770-776. 10.1038/ng.2293 |
Houlston, Richard S., Cheadle, Jeremy Peter and Maughan, Timothy Stanley 2012. COGENT (COlorectal cancer GENeTics) revisited. Mutagenesis 27 (2) , pp. 143-151. 10.1093/mutage/ger059 |
Maughan, Timothyn S., Adams, Richard A., Smith, Chris, Meade, Angela M., Seymour, Matthew T., Wilson, Richard H., Idziaszczyk, Shelley A., Harris, Rebecca, Fisher, David, Kenny, Sarah L., Kay, Edward, Mitchell, Jenna K., Madi, Ayman, Jasani, Bharat, James, Michelle D., Bridgewater, John, Kennedy, M. John, Claes, Bart, Lambrechts, Diether, Kaplan, Richard and Cheadle, Jeremy P. 2011. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. The Lancet 377 (9783) , pp. 2103-2114. 10.1016/S0140-6736(11)60613-2 |
Adams, Richard A., Meade, Angela M., Seymour, Matthew T., Wilson, Richard H., Madi, Ayman, Fisher, David, Kenny, Sarah L., Kay, Edward, Hodgkinson, Elizabeth, Pope, Malcolm, Rogers, Penny, Wasan, Harpreet, Falk, Stephen, Gollins, Simon, Hickish, Tamas, Bessell, Eric M., Propper, David, Kennedy, M. John, Kaplan, Richard and Maughan, Timothy S. 2011. Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. The Lancet Oncology 12 (7) , pp. 642-653. 10.1016/S1470-2045(11)70102-4 |
Seymour, Matthew T., Thompson, Lindsay C., Wasan, Harpreet S., Middleton, Gary, Brewster, A. E., Shepherd, Stephen F., O'Mahony, Marcella Sinead, Maughan, Timothy Stanley, Parmar, Mahesh and Langley, Ruth E. 2011. Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial. The Lancet 377 (9779) , pp. 1749-1759. 10.1016/S0140-6736(11)60399-1 |
Stead, M., Cameron, D., Lester, N., Parmar, M., Haward, R., Kaplan, R., Maughan, Timothy, Wilson, R., Campbell, H., Hamilton, R., Stewart, D., O'Toole, L., Kerr, D., Potts, V., Moser, R., Darbyshire, J. and Selby, P. 2011. Strengthening clinical cancer research in the United Kingdom. British Journal of Cancer 104 (10) , pp. 1529-1534. 10.1038/bjc.2011.69 |
Shaw, Paul, Maughan, Timothy Stanley and Clarke, Alan Richard 2011. Dual inhibition of epidermal growth factor and insulin-like 1 growth factor receptors reduce intestinal adenoma burden in the Apcmin/+ mouse. British Journal of Cancer 105 (5) , pp. 649-657. 10.1038/bjc.2011.291 |
Maughan, Timothy Stanley, Wilson, R. H., Williams, G. T., Seymour, M. T., Richman, S., Quirke, P. and Kaplan, R. S. 2011. Developing a biomarker-stratified trial design in advanced colorectal cancer: the MRC FOCUS 3 feasibility study. Journal of Clinical Oncology 29 (15 Sup) , TPS165. |
Houlston, Richard S, Cheadle, Jeremy Peter, Dobbins, Sara E., Tenesa, Albert, Jones, Angela M., Howarth, Kimberley, Spain, Sarah L., Broderick, Peter, Domingo, Enric, Farrington, Susan, Prendergast, James G. D., Pittman, Alan M., Theodoratou, Evi, Smith, Chris, Olver, Bianca, Walther, Axel, Barnetson, Rebecca A., Churchman, Michael, Jaeger, Emma E. M., Penegar, Steven, Barclay, Ella, Martin, Lynn, Gorman, Maggie, Mager, Rachel, Johnstone, Elaine, Midgley, Rachel, Niittymäki, Iina, Tuupanen, Sari, Colley, James, Idziaszczyk, Shelley Alexis, Thomas, Huw J. W., Lucassen, Anneke M., Evans, D. Gareth R., Maher, Eamonn R., Maughan, Timothy Stanley, Dimas, Antigone, Dermitzakis, Emmanouil, Cazier, Jean-Baptiste, Aaltonen, Lauri A., Pharoah, Paul, Kerr, David J., Carvajal-Carmona, Luis G., Campbell, Harry, Dunlop, Malcolm G. and Tomlinson, Ian P. M. 2010. Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33 [Letter]. Nature Genetics 42 (11) , pp. 973-977. 10.1038/ng.670 |
Maughan, Timothy Stanley, Illidge, T. M., Hoskin, P., McKenna, W. G., Brunner, T. B., Stratford, I. J., Harrington, K. J., Plummer, R., Billingham, L. J., Nutting, C., Burnet, N. G., Mackay, R. I., Oliver, A., Young, C. and Chan, C. S. K. 2010. Radiotherapy research priorities for the UK [Editorial]. Clinical Oncology 22 (8) , pp. 707-709. 10.1016/j.clon.2010.03.006 |
Jenkins, V., Farewell, Daniel, Batt, Linda, Maughan, Timothy, Branston, L., Langridge, C., Parlour, L., Farewell, V. and Fallowfield, L. 2010. The attitudes of 1066 patients with cancer towards participation in randomised clinical trials. British Journal of Cancer 103 (12) , pp. 1801-1807. 10.1038/sj.bjc.6606004 |
Maughan, Timothy, Adams, Richard, Wilson, Richard, Seymour, Matthew, Meade, Angela and Kaplan, Richard 2010. Chemotherapy-Free Intervals for Patients With Metastatic Colorectal Cancer Remain an Option [Letter]. Journal of Clinical Oncology 28 (17) , e275-e276. 10.1200/JCO.2009.27.8218 |
Mukherjee, S., Hurt, Chris Nicholas, Griffiths, G., Crosby, T. S., Staffurth, John Nicholas, Bridges, Sarah, Bridgewater, J. A., Mcdonald, A., Falk, S. and Maughan, Timothy Stanley 2010. A Cancer Research UK multicenter randomized phase II study of induction chemotherapy followed by gemcitabine- or capecitabine-based chemoradiotherapy for locally advanced nonmetastatic pancreatic cancer. American Journal of Clinical Oncology 28 |
Adams, Richard, Maughan, Timothy and Crosby, Tom 2009. Colon and rectum. In: Hanna, Louise, Crosby, Tom and Macbeth, Fergus eds. Practical Clinical Oncology, Cambridge University Press, pp. 159-173. (10.1017/CBO9780511545375.014) |
Adams, R. A., Meade, A. M., Madi, A., Fisher, D., Kay, E., Kenny, S., Kaplan, R. S. and Maughan, T. S. 2009. Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience. British Journal of Cancer 100 (2) , pp. 251-258. 10.1038/sj.bjc.6604877 |
Macbeth, Fergus R., Griffiths, Gareth O., Noble, Simon Ian Robert, Burns, Sarah and Maughan, Timothy Stanley 2009. Interim safety data on the FRAGMATIC trial: a randomised phase III clinical trial investigating the effect of FRAGMin® added to standard therapy in patients with lung cancer [Abstract]. Journal of Thoraric Oncology 4 (9) , S5-S968. 10.1097/JTO.0b013e3181b9c77e |
Maughan, Timothy Stanley 2009. A new opportunity for radiotherapy research in the UK [Editorial]. Clinical Oncology 21 (3) , pp. 157-158. 10.1016/j.clon.2008.12.007 |
Clements, D., Dhruva Rao, P., Ramanathan, D., Adams, R., Maughan, T. S. and Davies, M. M. 2009. Management of the asymptomatic primary in the palliative treatment of metastatic colorectal cancer. Colorectal Disease 11 (8) , pp. 845-848. 10.1111/j.1463-1318.2008.01695.x |
Griffiths, Gareth O., Burns, Sarah, Noble, Simon Ian Robert, Macbeth, Fergus R, Cohen, David and Maughan, Timothy Stanley 2009. Fragmatic: a randomised phase III clinical trial investigating the effect of fragmin® added to standard therapy in patients with lung cancer. BMC Cancer 9 , pp. 355-363. 10.1186/1471-2407-9-355 |
Adams, Richard, Meade, Angela, Wasan, Harpreet, Griffiths, Gareth O. and Maughan, Timothy Stanley 2008. Cetuximab therapy in first-line metastatic colorectal cancer and intermittent palliative chemotherapy: review of the COIN trial. Expert Review of Anticancer Therapy 8 (8) , pp. 1237-1245. 10.1586/14737140.8.8.1237 |
Maughan, Timothy Stanley and Rule, J. 2008. Ethics of PCT decision making on funding cancer treatments [Letter]. British Medical Journal (BMJ) 337 (7666) , pp. 367-368. 10.1136/bmj.a1243 |
Mukherjee, Saptarshi, Hudson, E., Reza, S., Thomas, M., Crosby, Thomas David Lewis and Maughan, Timothy Stanley 2008. Pancreatic cancer within a UK cancer network with special emphasis on locally advanced non-metastatic pancreatic cancer. Clinical Oncology 20 (7) , pp. 535-540. 10.1016/j.clon.2008.02.003 |
Maughan, Timothy Stanley, Topham, C., Lederman, J. and Seymour, M.T. 2007. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. The Lancet 370 (9582) , pp. 143-152. 10.1016/S0140-6736(07)61087-3 |
Newcombe, Robert Gordon, Davies, S., Brown, G. and Maughan, Timothy Stanley 2004. Effectiveness of preoperative staging in rectal cancer: digital rectal examination, endoluminal ultrasound or magnetic resonance imaging? British Journal of Cancer 91 (1) , pp. 23-29. 10.1038/sj.bjc.6601871 |
Crosby, Thomas David Lewis, Brewster, A. E., Borley, A., Perschky, L., Kehagioglou, Pinelopi, Court, J. and Maughan, Timothy Stanley 2004. Definitive chemoradiation in patients with inoperable oesophageal carcinoma. British Journal of Cancer 90 (1) , pp. 70-75. 10.1038/sj.bjc.6601461 |
Al-Mohammadi, A, Salek, Mir-saeed, Maughan, Timothy Stanley, Nicholls, P. J. and Mason, Malcolm David 2003. The impact of routine assessment of information needs on patient outcomes. Psycho-oncology 12 (6) , p. 641. 10.1002/pon.752 |
Maughan, Timothy Stanley, James, R.D., Kerr, D.J., Ledermann, J.A., Seymour, M.T., Topham, C., McArdle, C., Cain, D. and Stephens, R.J. 2003. Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial. The Lancet 361 (9356) , pp. 457-464. 10.1016/S0140-6736(03)12461-0 |
Maughan, Timothy Stanley, James, R.D., Kerr, D.J, Ledermann, J.A., McArdie, C., Seymour, M.T., Cohen, D., Hopwood, P., Johnston, C. and Stephens, R.J. 2002. Comparison of survival, palliation and quality of life with three chemotherapy regimens in metastatic colorectal cancer: a multi-centre randomised trial. The Lancet 359 (9317) , pp. 1555-1563. 10.1016/S0140-6736(02)08514-8 |
Finlay, Ilora Gillian, Maughan, Timothy Stanley and Webster, D. J. 1994. Portfolio learning: a proposal for undergraduate cancer teaching. Medical Education 28 (1) , pp. 79-82. 10.1111/j.1365-2923.1994.tb02690.x |
Maughan, T. S., Haylock, B., Hayward, M., Facey, P., Evans, W. D., Shelley, M. D., Fish, R. G. and Adams, M. 1990. OC125 immunoscintigraphy in ovarian carcinoma: a comparison with alternative methods of assessment. Clinical Oncology 2 (4) , pp. 199-205. 10.1016/s0936-6555(05)80168-2 |