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Howes, Joanna-Marie, Knauper, Vera, Malcor, Jean-Daniel and Farndale, Richard W 2020. Cleavage by MMP-13 renders VWF unable to bind to collagen but increases its platelet-reactivity. Journal of Thrombosis and Haemostatis 18 (4) , pp. 942-954. 10.1111/jth.14729 |
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Mohammed, Rebar N., Wehenkel, Sophie C., Galkina, Elena V., Yates, Emma-Kate, Preece, Graham, Newman, Andrew, Watson, H. Angharad, Ohme, Julia, Bridgeman, John S., Durairaj, Ruban R. P., Moon, Owen R., Ladell, Kristin, Miners, Kelly L., Dolton, Garry, Troeberg, Linda, Kashiwagi, Masahide, Murphy, Gillian, Nagase, Hideaki, Price, David A., Matthews, R. James, Knauper, Vera and Ager, Ann
2019.
ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Scientific Reports
9
, 5487.
10.1038/s41598-019-41811-z
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Mattern, Jens, Roghi, Christian S., Hurtz, Melanie, Knauper, Vera, Edwards, Dylan R. and Poghosyan, Zaruhi
2019.
ADAM15 mediates upregulation of Claudin-1 expression in breast cancer cells.
Scientific Reports
9
(1)
, 12540.
10.1038/s41598-019-49021-3
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Howes, Joanna-Marie, Pugh, Nicholas, Hamaia, Samir W, Jung, Stephanie M., Knauper, Vera, Malcor, Jean-Daniel and Farndale, Richard W 2018. MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation. Research and Practice in Thrombosis and Haemostasis 2 (2) , pp. 370-379. 10.1002/rth2.12088 |
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Gaweł-Bęben, K., Ali, N., Ellis, V., Velasco, G., Poghosyan, Z., Ager, Ann and Knauper, Vera
2018.
TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and
transmembrane serine proteases implicated in prostate cancer.
Cell Biology International
42
(3)
, pp. 273-280.
10.1002/cbin.10832
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Aeschlimann, Daniel and Knauper, Vera 2017. P2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis? Amino Acids 49 (3) , pp. 453-460. 10.1007/s00726-016-2319-8 |
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Chang, Gin-Wen, Hsiao, Cheng-Chih, Peng, Yen-Ming, Braga, Felipe A. Vieira, Kragten, Natasja A.M., Remmerswaal, Ester B. M., van de Garde, Martijn D. B., Straussberg, Rachel, König, Gabriele M., Kostenis, Evi, Knauper, Vera, Meyaard, Linde, van Lier, René A.W., van Gisbergen, Klaas P.J.M., Lin, Hsi-Hsien and Hamann, Jörg
2016.
The adhesion G protein-coupled receptor GPR56/ADGRG1 is an inhibitory receptor on human NK cells.
Cell Reports
15
(8)
, pp. 1757-1770.
10.1016/j.celrep.2016.04.053
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Adamczyk, Magdalena, Griffiths, Rhiannon, Dewitt, Sharon, Knauper, Vera and Aeschlimann, Daniel
2015.
P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2.
Journal of Cell Science
128
(24)
, pp. 4615-4628.
10.1242/jcs.175968
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Howes, Joanna-Marie, Pugh, Nicholas, Knauper, Vera and Farndale, Richard W. 2015. Modified platelet deposition on MMP-13 digested collagen I. Journal of Thrombosis and Haemostatis 13 (12) , pp. 2253-2259. 10.1111/jth.13166 |
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Wanger, Tim M., Dewitt, Sharon, Collins, Anne, Maitland, Norman J., Poghosyan, Zaruhi and Knauper, Vera
2015.
Differential regulation of TROP2 release by PKC isoforms through vesicles and ADAM17.
Cellular Signalling
27
(7)
, pp. 1325-1335.
10.1016/j.cellsig.2015.03.017
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Muller, Anne, Leinweber, Brinja, Fischer, Jana, Muller, Timo D., Gruters, Annette, Tschop, Matthias H., Knauper, Vera, Biebermann, Heike and Kleinau, Gunnar 2014. The extracellular N-terminal domain of G-protein coupled receptor 83 regulates signaling properties and is an intramolecular inverse agonist. BMC Research Notes 7 , 913. 10.1186/1756-0500-7-913 |
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Howes, Joanna-Marie, Bihan, Dominique, Slatter, David A., Hamaia, Samir W., Packman, Len C., Knauper, Vera, Visse, Robert and Farndale, Richard W.
2014.
The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage.
Journal of Biological Chemistry
289
, pp. 24091-24101.
10.1074/jbc.M114.583443
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Qi, Jian Hua, Ebrahem, Quteba, Ali, Mariya, Cutler, Alecia, Bell, Brent, Prayson, Nicholas, Sears, Jonathan, Knauper, Vera, Murphy, Gillian and Anand-Apte, Bela 2013. Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice. PLoS ONE 8 (3) , e55667. 10.1371/journal.pone.0055667 |
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Knauper, Vera and Murphy, Gillian 2010. Methods for studying activation of matrix metalloproteinases. Methods Mol Biol 622 , pp. 233-43. 10.1007/978-1-60327-299-5_14 |
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Ali, N., Fiedler, L. and Knauper, Vera Louise Frieda 2009. ADAMTS4 mediated signalling alters cell morphology and motility. International Journal of Experimental Pathology 90 (1) , A60-A61. |
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Worley, Joanna R., Thompkins, Philip B., Lee, Meng H., Hutton, Mike, Soloway, Paul, Edwards, Dylan R., Murphy, Gillian and Knauper, Vera 2003. Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP). Biochemical Journal 372 (3) , pp. 799-809. 10.1042/BJ20021573 |
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Knauper, Vera, Bailey, Louise, Worley, Joanna R., Soloway, Paul, Patterson, Margaret L. and Murphy, Gillian 2002. Cellular activation of proMMP-13 by MT1-MMP depends on the C-terminal domain of MMP-13. FEBS Letters 532 (1-2) , pp. 127-130. 10.1016/S0014-5793(02)03654-2 |
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Lee, Meng-Huee, Maskos, Klaus, Knauper, Vera, Dodds, Philippa and Murphy, Gillian 2002. Mapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering. Protein Science 11 (10) , pp. 2493-2503. 10.1110/ps.0216202 |
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Lafleur, Marc A., Handsley, Madeleine M., Knauper, Vera, Murphy, Gillian and Edwards, Dylan R. 2002. Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs). Journal of Cell Science 115 (17) , pp. 3427-3438. |
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Amour, Augustin, Knight, C. Graham, English, William R., Webster, Ailsa, Slocombe, Patrick M., Knauper, Vera, Docherty, Andrew J. P., Becherer, J. David, Blobel, Carl P. and Murphy, Gillian 2002. The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Letters 524 (1-3) , pp. 154-158. 10.1016/S0014-5793(02)03047-8 |
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Lee, Meng-Huee, Verma, Vandana, Maskos, Klaus, Becherer, J. David, Knauper, Vera, Dodds, Philippa, Amour, Augustin and Murphy, Gillian 2002. The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3. FEBS Letters 520 (1-3) , pp. 102-106. 10.1016/S0014-5793(02)02776-X |
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Lee, Meng-Huee, Verma, Vandana, Maskos, Klaus, Nath, Deepa, Knauper, Vera, Dodds, Philippa, Amour, Augustin and Murphy, Gillian 2002. Engineering N-terminal domain of tissue inhibitor of metalloproteinase (TIMP)-3 to be a better inhibitor against tumour necrosis factor-a-converting enzyme. Biochemical Journal -London- 364 , pp. 227-234. |
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Bailey, Louise, Wienke, Dirk, Howard, Matthew, Knauper, Vera, Isacke, Clare M. and Murphy, Gillian 2002. Investigation of the role of Endo180/urokinase-type plasminogen activator receptor-associated protein as a collagenase 3 (matrix metalloproteinase 13) receptor. Biochemical Journal -London- 363 (1) , pp. 67-72. |
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Stringa, E., White, D., Tuan, R. S., Knauper, Vera and Gavrilovic, J. 2002. Role of newly synthesized fibronectin in vascular smooth muscle cell migration on matrix-metalloproteinase-degraded collagen. Biochemical Society Transactions 30 , pp. 102-111. |
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Rodriguez-Manzaneque, Juan Carlos, Westling, Jennifer, Thai, Shelley N. M., Luque, Alfonso, Knauper, Vera, Murphy, Gillian, Sandy, John D. and Iruela-Arispe, M. Luisa 2002. ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors. Biochemical and Biophysical Research Communications 293 (1) , pp. 501-508. 10.1016/S0006-291X(02)00254-1 |
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English, William R., Holtz, Beatrice, Vogt, Gavin, Knauper, Vera and Murphy, Gillian 2001. Characterization of the role of the "MT-loop" - an eight-amino acid insertion specific to progelatinase A (MMP2) activating membrane-type matrix metalloproteinases. Journal of Biological Chemistry 276 (45) , pp. 42018-42026. 10.1074/jbc.M107783200 |
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Knauper, Vera, Balbin, M, Fueyo, A and Lopez-Otin, C 2001. Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation. Journal of Biological Chemistry 276 (13) , pp. 10253-10262. |
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Knauper, Vera, Patterson, Margaret L., Gomis-Ruth, Franz X., Smith, Bryan, Lyons, Alan, Docherty, Andrew J.P. and Murphy, Gillian 2001. The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificity and inhibitor selectivity. European Journal of Biochemistry 268 (6) , pp. 1888-1896. 10.1046/j.1432-1327.2001.02062.x |
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