![]() | Up a level |
Rosas, Marcela, Slatter, David A., Obaji, Samya G., Webber, Jason P., Alvarez-Jarreta, Jorge, Thomas, Christopher P., Aldrovandi, Maceler, Tyrrell, Victoria J., Jenkins, Peter V., O'Donnell, Valerie B. and Collins, Peter W.
2020.
The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles.
PLoS ONE
15
(10)
, e0240189.
10.1371/journal.pone.0240189
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Ipseiz, Natacha, Pickering, Robert J., Rosas, Marcela, Tyrrell, Victoria J., Davies, Luke C., Orr, Selinda J., Czubala, Magdalena A., Fathalla, Dina, Robertson, Avril A. B., Bryant, Clare E., O'Donnell, Valerie and Taylor, Philip R.
2020.
Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway.
EMBO Journal
39
(14)
, e103454.
10.15252/embj.2019103454
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Meckelmann, Sven W., Hawksworth, Jade I., White, Daniel, Andrews, Robert, Rodrigues, Patricia, O'Connor, Anne, Alvarez-Jarreta, Jorge, Tyrrell, Victoria J., Hinz, Christine, Zhou, You, Williams, Julie, Aldrovandi, Maceler, Watkins, William J., Engler, Adam J., Lo Sardo, Valentina, Slatter, David A., Allen, Stuart M., Acharya, Jay, Mitchell, Jacquie, Cooper, Jackie, Aoki, Junken, Kano, Kuniyuki, Humphries, Steve E. and O'Donnell, Valerie B. 2020. Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274. Circulation: Genomic and Precision Medicine 13 (3) , pp. 149-164. 10.1161/CIRCGEN.119.002806 |
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Gallagher, Hayley, Williams, Jessica O., Ferekidis, Nele, Ismail, Alaa, Chan, Yee-Hung, Michael, Daryn R., Guschina, Irina A., Tyrrell, Victoria J., O'Donnell, Valerie B., Harwood, John L., Khozin-Goldberg, Inna, Boussiba, Sammy and Ramji, Dipak P.
2019.
Dihimo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis.
BBA - Molecular Basis of Disease
1865
(9)
, pp. 2538-2550.
10.1016/j.bbadis.2019.06.011
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Kornilov, Andrei, Kennedy, Paul D., Aldrovandi, MacEler, Watson, Andrew J. A., Hinz, Christine, Harless, Bryan, Colombo, Joseph, Maxey, Kirk M., Tyrrell, Victoria J., Simon, Matthew, Aggarwal, Varinder K., Boeglin, William E., Brash, Alan R., Murphy, Robert C. and O'Donnell, Valerie B.
2019.
Revising the structure of a new eicosanoid from human platelets to 8,9-11,12-diepoxy-13-
hydroxy-eicosadienoic acid.
Journal of Biological Chemistry
294
, pp. 9225-9238.
10.1074/jbc.RA119.008915
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Allen-Redpath, Keith, Aldrovandi, Maceler, Lauder, Sarah N., Gketsopoulou, Anastasia, Tyrrell, Victoria J., Slatter, David A., Andrews, Robert, Watkins, W. John, Atkinson, Georgia, McNeill, Eileen, Gilfedder, Anna, Protty, Majd, Burston, James, Johnson, Sam R. C., Rodrigues, Patricia R. S., Jones, Dylan O., Lee, Regent, Handa, Ashok, Channon, Keith, Obaji, Samya, Alvarez-Jarreta, Jorge, Krönke, Gerhard, Ackermann, Jochen, Jenkins, P. Vince, Collins, Peter W. and O'Donnell, Valerie B.
2019.
Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.
Proceedings of the National Academy of Sciences
116
(16)
, pp. 8038-8047.
10.1073/pnas.1814409116
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Slatter, David A., Percy, Charles L., Allen-Redpath, Keith, Gajsiewicz, Joshua M., Brooks, Nick J., Clayton, Aled, Tyrrell, Victoria J., Rosas, Marcela, Lauder, Sarah N., Watson, Andrew, Dul, Maria, Garcia-Diaz, Yoel, Aldrovandi, MacEler, Heurich, Meike, Hall, Judith, Morrissey, James H., Lacroix-Desmazes, Sebastien, Delignat, Sandrine, Jenkins, P. Vincent, Collins, Peter W. and O'Donnell, Valerie B.
2018.
Enzymatically-oxidized phospholipids restore thrombin generation in coagulation factor deficiencies.
JCI Insight
3
(6)
, e98459.
10.1172/jci.insight.98459
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Zhao, Jingmin, Minami, Yoshinori, Etling, Emily, Coleman, John M., Lauder, Sarah, Tyrrell, Victoria, Aldrovandi, Maceler, O'Donnell, Valerie Bridget, Claesson, Hans-Erik, Kagan, Valerian and Wenzel, Sally 2017. Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 57 (6) 10.1165/rcmb.2017-0031OC |
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Lauder, Sarah N., Allen-Redpath, Keith, Slatter, David A., Aldrovandi, Maceler, O'Connor, Anne, Farewell, Daniel, Percy, Charles L., Molhoek, Jessica E., Rannikko, Sirpa, Tyrrell, Victoria J., Ferla, Salvatore, Milne, Ginger L., Poole, Alastair W., Thomas, Christopher P., Obaji, Samya, Taylor, Philip R., Jones, Simon A., deGroot, Philip G., Urbanus, Rolf T., Horkko, Sohvi, Uderhardt, Stefan, Ackermann, Jochen, Jenkins, P. Vince, Brancale, Andrea, Kronke, Gerhard, Collins, Peter W. and O'Donnell, Valerie B.
2017.
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.
Science Signaling
10
(507)
, eaan2787.
10.1126/scisignal.aan2787
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Uderhardt, Stefan, Ackermann, Jochen, Fillep, Tobias, Hammond, Victoria J., Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R., Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Diete, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W., Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L., Lee, James J., Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B. and Krönke, Gerhard
2017.
Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis and thrombotic disease.
Journal of Experimental Medicine
214
(7)
, pp. 2121-2138.
10.1084/jem.20161070
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Aldrovandi, MacEler, Hinz, Christine, Lauder, Sarah N, Podmore, Helen, Hornshaw, Martin, Slatter, David A, Tyrrell, Victoria J, Clark, Stephen R, Marnett, Lawrence J., Collins, Peter W, Murphy, Robert C and O'Donnell, Valerie B 2017. DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. Redox Biology 11 , pp. 663-672. 10.1016/j.redox.2017.01.001 |
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Lauder, Sarah N., Tyrrell, Victoria J., Allen-Redpath, Keith, Aldrovandi, MacEler, Gray, David, Collins, Peter, Jones, Simon A., Taylor, Philip R. and O'Donnell, Valerie 2017. Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo. Wellcome Open Research 2 (1) 10.12688/wellcomeopenres.10308.1 |
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Liao, Chia-Te, Rosas, Marcela, Davies, Luke C., Giles, Peter J., Tyrrell, Victoria J., O'Donnell, Valerie B., Topley, Nicholas, Humphreys, Ian R., Fraser, Donald J., Jones, Simon A. and Taylor, Philip R.
2016.
IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation.
European Journal of Immunology
46
(9)
, pp. 2222-2232.
10.1002/eji.201646528
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Morgan, Alwena H., Hammond, Victoria J., Sakoh-Nakatogawa, Machiko, Ohsumi, Yoshinori, Thomas, Christopher P., Blanchet, Fabien, Piguet, Vincent, Kiselyov, Kirill and O'Donnell, Valerie Bridget 2015. A novel role for 12/15-lipoxygenase in regulating autophagy. Redox Biology 4 , pp. 40-47. 10.1016/j.redox.2014.11.005 |
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Friedmann Angeli, Jose Pedro, Schneider, Manuela, Proneth, Bettina, Tyurina, Yulia Y., Tyurin, Vladimir A., Hammond, Victoria J., Herbach, Nadja, Aichler, Michaela, Walch, Axel, Eggenhofer, Elke, Basavarajappa, Devaraj, Rådmark, Olof, Kobayashi, Sho, Seibt, Tobias, Beck, Heike, Neff, Frauke, Esposito, Irene, Wanke, Rüdiger, Förster, Heidi, Yefremova, Olena, Heinrichmeyer, Marc, Bornkamm, Georg W., Geissler, Edward K., Thomas, Stephen B., Stockwell, Brent R., O'Donnell, Valerie B., Kagan, Valerian E., Schick, Joel A. and Conrad, Marcus 2014. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nature Cell Biology 16 , pp. 1180-1194. 10.1038/ncb3064 |
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Mathie, S. A., Dixon, K. L., Walker, S. A., Tyrell, Victoria Jayne, Mondhe, M., O'Donnell, Valerie Bridget, Gregory, L. G. and Lloyd, C. M. 2014. Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge. Allergy 70 (1) , pp. 80-89. 10.1111/all.12536 |
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Thomas, Christopher P., Clark, Stephen Robert, Hammond, Victoria Jayne, Aldrovandi, Maceler, Collins, Peter William and O'Donnell, Valerie Bridget 2014. Identification and quantification of aminophospholipid molecular species on the surface of apoptotic and activated cells. Nature Protocols 9 (1) , pp. 51-63. 10.1038/nprot.2013.163 |
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Aldrovandi, Maceler, Hammond, Victoria Jayne, Podmore, Helen, Hornshaw, Martin, Clark, Stephen Robert, Marnett, Lawrence J., Slatter, David, Murphy, Robert C., Collins, Peter William and O'Donnell, Valerie Bridget 2013. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. Journal of Lipid Research 54 (11) , pp. 3085-3097. 10.1194/jlr.M041533 |
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Clark, Stephen Robert, Thomas, Christopher P., Hammond, Victoria Jayne, Aldrovandi, Maceler, Wilkinson, Gavin William Grahame, Hart, Keith William, Murphy, Robert C., Collins, Peter William and O'Donnell, Valerie Bridget 2013. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proceedings of the National Academy of Sciences of the United States of America 110 (15) , pp. 5875-5880. 10.1073/pnas.1222419110 |
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Hammond, Victoria Jayne, Morgan, Alwena H., Lauder, Sarah Nicol, Thomas, Christopher P., Brown, Sarah, Freeman, Bruce A., Lloyd, Clare M., Davies, Jane, Bush, Andrew, Levonen, Anna-Liisa, Kansanen, Emilia, Villacorta, Luis, Chen, Y. Eugene, Porter, Ned, Garcia-Diaz, Yoel M., Schopfer, Francisco J. and O'Donnell, Valerie Bridget 2012. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. Journal of Biological Chemistry 287 (50) , pp. 41651-41666. 10.1074/jbc.M112.405407 |
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Hammond, Victoria Jayne and O'Donnell, Valerie Bridget 2012. Esterified eicosanoids: generation, characterization and function. Biochimica et Biophysica Acta - Biomembranes 1818 (10) , pp. 2403-2412. 10.1016/j.bbamem.2011.12.013 |
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Clark, Stephen Robert, Guy, Christopher J., Scurr, Martin J., Taylor, Philip Russel, Kift-Morgan, Ann Patricia, Hammond, Victoria Jayne, Thomas, Christopher P., Coles, Barbara, Roberts, Gareth Wyn, Eberl, Matthias, Jones, Simon Arnett, Topley, Nicholas, Kotecha, Sailesh and O'Donnell, Valerie Bridget 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117 (6) , pp. 2033-2043. 10.1182/blood-2010-04-278887 |
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Jones, Gareth Wyn, McLoughlin, Rachel Mary, Hammond, Victoria Jayne, Parker, Clare Rhian, Williams, John, Malhotra, Raj, Scheller, Jurgen, Williams, Anwen, Rose-John, Stefan, Topley, Nicholas and Jones, Simon Arnett 2010. Loss of CD4+ T Cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. The Journal of Immunology 184 (4) , pp. 2130-2139. 10.4049/jimmunol.0901528 |
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Jones, Gareth Wyn, McLoughlin, R. M., Hammond, Victoria Jayne, Parker, Clare R., Williams, John D., Malhotra, R., Scheller, J., Williams, Anwen Sian, Rose-John, Stefan, Topley, Nicholas and Jones, Simon Arnett 2010. Loss of CD4(+) T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. Journal of Immunology 184 (4) , pp. 2130-2139. |
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Morgan, Alwena Haf, Hammond, Victoria Jayne, Morgan, Lloyd, Thomas, Christopher P., Tallman, Keri A., Garcia-Diaz, Yoel Ruslan, McGuigan, Christopher, Serpi, Michaela, Porter, Ned A., Murphy, Robert C. and O'Donnell, Valerie Bridget 2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5 (12) , pp. 1919-1931. 10.1038/nprot.2010.162 |
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Hams, Emily, Colmont, Chantal S., Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2008. Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180. |
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Hams, Emily, Dioszechy, Vincent, Colmont, Chantal Sophie, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2007. Oncostatin M receptor signalling regulates monocytic cell trafficking during acute inflammation [Abstract]. Cytokine 39 (1) , p. 14. 10.1016/j.cyto.2007.07.053 |
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