ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Number of items: 33.
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Turnham, Daniel, Yang, William W., Davies, Julia, Varnava, Athina, Ridley, Anne J., Conlan, Steven R. and Clarkson, Richard W.E.
2020.
Bcl-3 promotes multi-modal tumour cell migration via NF-kB1 mediated regulation of Cdc42.
Carcinogenesis
10.1093/carcin/bgaa005
Item availability restricted. |
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Healey, Gareth D., Pan-Castillo, Belen, Garcia-Parra, Jezabel, Davies, Julia, Roberts, Shaun, Jones, Eilir, Dhar, Kalyan, Nandanan, Sarika, Tofazzal, Nasima, Piggott, Luke, Clarkson, Richard, Seaton, Gillian, Frostell, Asa, Fagge, Tim, McKee, Colin, Margarit, Lavinia, Conlan, R. Steven and Gonzalez, Deyarina
2019.
Antibody drug conjugates against the receptor for advanced glycation end products (RAGE), a novel therapeutic target in endometrial cancer.
Journal for ImmunoTherapy of Cancer
7
(1)
, 280.
10.1186/s40425-019-0765-z
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Pearson, Helen, Li, Jason, Meniel, Valerie, Fennell, Christina, Waring, Paul, Montgomery, Karen, Rebello, Richard, Macpherson, Arthi, Koushyar, Sarah, Furic, Luc, Cullinane, Carleen, Clarkson, Richard, Smalley, Matthew, Simpson, Kaylene, Phesse, Toby, Shepherd, Peter, Humbert, Patrick, Sansom, Owen and Phillips, Wayne
2018.
Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth.
Cancer Discovery
8
(6)
, pp. 764-779.
10.1158/2159-8290.CD-17-0867
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Piggott, Luke, Silva, Ana, Robinson, Timothy, Santiago-Gomez, Angelica, Simoes, Bruno M., Becker, Michael, Fichtner, Iduna, Andera, Ladislav, Young, Philippa, Morris, Christine, Barret-Lee, Peter, Alchami, Fouad, Piva, Marco, Vivanco, Maria d. M., Clarke, Robert B., Gee, Julia M. W. and Clarkson, Richard
2018.
Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through post-translational downregulation of c-FLIP.
Clinical Cancer Research
24
(10)
, pp. 2452-2463.
10.1158/1078-0432.CCR-17-1381
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| Chen, Hung-Chang, Joalland, Noémie, Bridgeman, John S, Alchami, Fouad S, Jarry, Ulrich, Khan, Mohd Wajid A, Piggott, Luke, Shanneik, Yasmin, Li, Jianqiang, Herold, Marco J, Herrmann, Thomas, Price, David A., Gallimore, Awen M., Clarkson, Richard W., Scotet, Emmanuel, Moser, Bernhard and Eberl, Matthias 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7) , pp. 620-629. 10.1038/icb.2017.21 |
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| Yeo, Syn Kok, French, Rhiannon, Filomena, Spada and Clarkson, Richard 2017. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment 162 (3) , pp. 465-477. 10.1007/s10549-017-4149-0 |
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| Sharma, Sunil, Narayanasamy, Ganesh, Clarkson, Richard, Chao, Ming, Moros, Eduardo G., Zhang, Xin, Yan, Yulong, Boerma, Marjan, Paudel, Nava, Morrill, Steven, Corry, Peter and Griffin, Robert J. 2017. Study of image qualities from 6D robot-based CBCT imaging system of small animal irradiator. Technology in Cancer Research & Treatment 16 (6) , pp. 811-818. 10.1177/1533034617700558 |
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| Sharma, Sunil, Narayanasamy, Ganesh, Przybyla, Beata, Webber, Jessica, Boerma, Marjan, Clarkson, Richard, Moros, Eduardo G., Corry, Peter M. and Griffin, Robert J. 2017. Advanced small animal conformal radiation therapy device. Technology in Cancer Research and Treatment 16 (1) , pp. 45-56. 10.1177/1533034615626011 |
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| Yeo, Syn Kok, Ali, Ahmed Y., Hayward, Olivia A., Turnham, Daniel, Jackson, Troy, Bowen, Ifor D. and Clarkson, Richard 2016. Bisabolene, a sesquiterpene from the essential oil extract of opoponax (Commiphora guidottii), exhibits cytotoxicity in breast cancer cell lines. Phytotherapy Research 30 (3) , pp. 418-425. 10.1002/ptr.5543 |
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| French, Rhiannon, Hayward, Olivia, Jones, Samuel, Yang, William and Clarkson, Richard 2015. Cytoplasmic levels of cFLIP determine a broad susceptibility of breast cancer stem/progenitor-like cells to TRAIL. Molecular Cancer 14 (1) , 209. 10.1186/s12943-015-0478-y |
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Piggott, Luke, Omidvar, Nader, Martí Pérez, Salvador, French, Rhiannon, Eberl, Matthias and Clarkson, Richard W. E.
2015.
Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL.
Breast Cancer Research
17
(1)
, p. 96.
10.1186/s13058-015-0597-9
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| Ali, Ahmed Yasine, Yeo, Syn, Ellis, Sadie, Ade, Jamilla, Clarkson, Richard W. E., Esa, Adam, Blain, Emma Jane, Bowen, Ifor D. and Martin, Tracey Amanda 2015. Anti-metastatic and cytotoxic properties of frankincense and scented myrrh. Anticancer Research 35 (7) , pp. 4310-4311. |
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Cowley, Michael, Garfield, Alastair S., Madon-Simon, Marta, Charalambous, Marika, Clarkson, Richard W. E., Smalley, Matthew John, Kendrick, Howard, Isles, Anthony Roger, Parry, Aled J., Carney, Sara, Oakey, Rebecca J., Heisler, Lora K., Moorwood, Kim, Wolf, Jason B. and Ward, Andrew
2014.
Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup.
PLoS Biology
12
(2)
, e1001799.
10.1371/journal.pbio.1001799
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| Wakefield, Alison Myfanwy, Soukupová, Jitka, Montagne, Amelie, Ranger, Jill, French, Rhiannon, Muller, William and Clarkson, Richard W. E. 2013. Bcl3 selectively promotes metastasis of ErbB2-driven mammary tumors. Cancer Research 73 (2) , pp. 745-755. 10.1158/0008-5472.CAN-12-1321 |
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| Smalley, Matthew John, Piggott, Luke and Clarkson, Richard W. E. 2013. Breast cancer stem cells: obstacles to therapy. Cancer Letters 338 (1) , pp. 57-62. 10.1016/j.canlet.2012.04.023 |
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| Soukupova, J., Brancale, Andrea, Westwell, Andrew D. and Clarkson, Richard W. E. 2012. Inhibitors of Bcl-3 as a novel therapeutic strategy for HER2+ breast cancer. European Journal of Cancer 48 (5) , S225-S225. |
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| Piggott, Luke, Omidvar, Nader, Marti-Perez, Salvador, Eberl, Matthias and Clarkson, Richard W. E. 2011. Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 13 (5) , R88. 10.1186/bcr2945 |
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| Kreuzaler, Peter A., Staniszewska, Anna D., Li, Wenjing, Omidvar, Nader, Kedjouar, Blandine, Turkson, James, Poli, Valeria, Flavell, Richard A., Clarkson, Richard W. E. and Watson, Christine J. 2011. Stat3 controls lysosomal-mediated cell death in vivo. Nature Cell Biology 13 (3) , pp. 303-309. 10.1038/ncb2171 |
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| Knight, James Christopher, Hallett, Andrew Jon, Brancale, Andrea, Paisey, Stephen James, Clarkson, Richard W. E. and Edwards, Peter Gerald 2011. Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor. ChemBioChem 12 (17) , pp. 2692-2698. 10.1002/cbic.201100441 |
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| Jasani, Bharat, Gee, Julia Margaret Wendy, Hutcheson, Iain Robert, Clarkson, Richard W. E., Bartlett, J. and Barrett-Lee, Peter 2009. Resistance to HER2-directed trastuzumab therapy in breast cancer. Advances in Breast Cancer 6 (3) , pp. 11-18. |
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| Wakefield, A., Piggott, Luke, Croston, D., Jiang, W. G. and Clarkson, Richard W. E. 2008. Suppression of the NF-kappa B cofactor Bcl3 inhibits mammary epithelial cell apoptosis and, in breast tumours, correlates with poor prognosis. Breast Cancer Research 10 (S2) , O4. 10.1186/bcr1884 |
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| Tiffen, P., Omidvar, Nader, Marquez, Nuria, Croston, D., Watson, C. and Clarkson, Richard W. E. 2008. A dual role for Oncostatin M signalling in the differentiation and death of mammary epithelial cells in vivo. Molecular Endocrinology 22 (12) , pp. 2677-2688. 10.1210/me.2008-0097 |
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| Sykacek, P., Clarkson, Richard W. E., Print, C., Furlong, R. and Micklem, G. 2007. Bayesian modelling of shared gene function. Bioinformatics 23 (15) , pp. 1936-1944. 10.1093/bioinformatics/btm280 |
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| Clarkson, Richard W. E., Boland, Marion P., Kritikou, Ekaterini A., Lee, Jennifer M., Freeman, Tom C., Tiffen, Paul G. and Watson, Christine J. 2006. The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Molecular Endocrinology 20 (3) , pp. 675-685. 10.1210/me.2005-0392 |
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| Abell, Kathrine, Bilancio, Antonio, Clarkson, Richard W. E., Tiffen, Paul G., Altaparmakov, Anton I., Burdon, Thomas G., Asano, Tomoichiro, Vanhaesebroeck, Bart and Watson, Christine J. 2005. Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. Nature Cell Biology Vol. 7 (4) , pp. 392-398. 10.1038/ncb1242 |
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| Sorrell, David A., Szymanowska, Malgorzata, Boutinaud, Marion, Robinson, Claire, Clarkson, Richard W. E., Stein, Torsten, Flint, David J. and Kolb, Andreas F. 2005. Regulation of genes encoding proteolytic enzymes during mammary gland development. Journal of Dairy Research 72 (04) , pp. 433-441. 10.1017/S0022029905001202 |
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| Clarkson, Richard W. E., Wayland, M. T., Lee, J., Freeman, T. and Watson, C. J. 2004. Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression. Breast Cancer Research 6 (2) , R92-R109. |
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| Clarkson, Richard W. E., Corti, C., Ferraguti, F. and Xuereb, J.H. 2003. Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells. Journal of Biological Chemistry Vol. 2 (No.35) , pp. 33105-33119. 10.1074/jbc.M212380200 |
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| Kritikou, Ekaterini A., Sharkey, Andrew, Abell, Kathrine, Came, Paul J., Anderson, Elizabeth, Clarkson, Richard W. E. and Watson, Christine J. 2003. A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development 130 (15) , pp. 3459-3468. 10.1242/dev.00578 |
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| Clarkson, Richard W. E. and Watson, Christine J. 2003. Microarray analysis of the involution switch. Journal of Mammary Gland Biology and Neoplasia 8 (3) , pp. 309-319. 10.1023/B:JOMG.0000010031.53310.92 |
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| Clarkson, Richard W. E. 2002. lkB kinase alpha: a link in the chain of the mammary cycle. Breast Cancer Research 4 , 173. 10.1186/bcr446 |
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| Gordon, K., Binas, B., Chapman, R. S., Kurian, K. M., Clarkson, Richard W. E., Clark, A. J., Lane, E. B. and Watson, C. J. 2000. A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Research 2 , pp. 222-235. 10.1186/bcr57 |
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| Clarkson, Richard W. E., Heeley, JoannaLL., Chapman, Rachel, Aillet, Fabienne, Hay, Ronald T., Wyllie, Andrew and Watson, Christine J. 2000. NF-kappa B inhibits apoptosis in murine mammary epithelia. Journal of Biological Chemistry 275 (17) , pp. 12737-12742. 10.1074/jbc.275.17.12737 |
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