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Number of items: 36.

Knapper, Steven, Russell, Nigel, Gilkes, Amanda, Hills, Robert K., Gale, Rosemary E., Cavenagh, James D., Jones, Gail, Kjeldsen, Lars, Grunwald, Michael R., Thomas, Ian, Konig, Heiko, Levis, Mark J. and Burnett, Alan K. 2017. A randomized assessment of adding the kinase inhibitor lestaurtinib to first-line chemotherapy for FLT3-mutated AML. Blood 129 (9) , pp. 1143-1154. 10.1182/blood-2016-07-730648
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Khan, N, Hills, Robert, Virgo, P, Couzens, S, Clark, N, Gilkes, Amanda, Richardson, P, Knapper, Steven, Grimwade, D, Russell, N H, Burnett, Alan and Freeman, S D 2016. Expression of CD33 is a predictive factor for effect of gemtuzumab ozogamicin at different doses in adult acute myeloid leukaemia. Leukemia 31 (5) , pp. 1059-1068. 10.1038/leu.2016.309
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Ivey, Adam, Hills, Robert Kerrin, Simpson, Michael A., Jovanovic, Jelena V., Gilkes, Amanda F., Grech, Angela, Patel, Yashma, Bhudia, Neesa, Farah, Hassan, Mason, Joanne, Wall, Kerry, Akiki, Susanna, Griffiths, Michael, Solomon, Ellen, McCaughan, Frank, Linch, David C., Gale, Rosemary E., Vyas, Paresh, Freeman, Sylvie D., Russell, Nigel, Burnett, Alan K. and Grimwade, David 2016. Assessment of minimal residual disease in standard-risk AML. New England Journal of Medicine 374 (5) , pp. 422-433. 10.1056/NEJMoa1507471

Kuhnl, A., Valk, P. J. M., Sanders, M. A., Ivey, A., Hills, Robert Kerrin, Mills, K. I., Gale, R. E., Kaiser, M. F., Dillon, R., Joannides, M., Gilkes, Amanda F., Haferlach, T., Schnittger, S., Duprez, E., Linch, D. C., Delwel, R., Lowenberg, B., Baldus, C. D., Solomon, E., Burnett, Alan K. and Grimwade, D. 2015. Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia. Blood 125 (19) , pp. 2985-2994. 10.1182/blood-2014-12-613703

Ostronoff, F., Othus, M., Lazenby, Michelle, Estey, E., Appelbaum, F. R., Evans, Anna, Godwin, J., Gilkes, Amanda F., Kopecky, K. J., Burnett, Alan, List, A. F., Fang, M., Oehler, V. G., Petersdorf, S. H., Pogosova-Agadjanyan, E. L., Radich, J. P., Willman, C. L., Meshinchi, S. and Stirewalt, D. L. 2015. Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: A SWOG and UK National Cancer Research Institute/Medical Research Council report. Journal of Clinical Oncology 33 (10) , pp. 1157-1164. 10.1200/JCO.2014.58.0571

Lazenby, Michelle, Gilkes, Amanda, Marrin, C., Evans, Anna, Hills, Robert Kerrin and Burnett, A. K. 2014. The prognostic relevance of flt3 and npm1 mutations on older patients treated intensively or non-intensively: a study of 1312 patients in the UK NCRI AML16 trial. Leukemia 28 , pp. 1953-1959. 10.1038/leu.2014.90

Daud, Siti Sarah, Pumford, Sara L, Gilmour, Marie N., Gilkes, Amanda F., Burnett, Alan Kenneth, Hills, Robert Kerrin, Tonks, Alex and Darley, Richard Lawrence 2012. Identification of the Wnt signalling protein, TCF7L2 as a significantly overexpressed transcription factor in AML [Abstract]. Blood 120 (21) , 1281.

Mohamedali, Azim M., Hills, Robert Kerrin, Nasser, Erick E., Abdallah, Atiyeh, Shinde, Sneha, Kulasekararaj, Austin G., Gilkes, Amanda F., Lea, Nicholas, Burnett, Alan Kenneth and Mufti, Ghulam J. 2011. Single Nucleotide Polymorphism Array (SNP-A) karyotype is the best predictor of prognosis in normal cytogenetics Acute Myeloid Leukaemia (AML). Blood -New York- 118 (21) , pp. 188-189.

Goardon, Nicolas, Marchi, Emanuele, Atzberger, Ann, Quek, Lynn, Schuh, Anna, Soneji, Shamit, Woll, Petter, Mead, Adam, Alford, Kate A., Rout, Raj, Chaudhury, Salma, Gilkes, Amanda F., Knapper, Steven, Beldjord, Kheira, Begum, Suriya, Rose, Susan, Geddes, Nicola, Griffiths, Mike, Standen, Graham, Sternberg, Alexander, Cavenagh, Jamie, Hunter, Hannah, Bowen, David, Killick, Sally, Robinson, Lisa, Price, Andrew, Macintyre, Elizabeth, Virgo, Paul, Burnett, Alan Kenneth, Craddock, Charles, Enver, Tariq, Jacobsen, Sten Eirik W., Porcher, Catherine and Vyas, Paresh 2011. Coexistence Of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia. Cancer Cell 19 (1) , pp. 138-152. 10.1016/j.ccr.2010.12.012

Mohamedali, A., Hills, Robert Kerrin, Nasser, E. E., Abdallah, A., Kulasekararaj, A. G., Gilkes, Amanda F., Lea, N., Burnett, Alan Kenneth and Mufti, G. J. 2010. Prognostic significance of cryptic genomic aberrations in AML with normal karyotype [Abstract]. Blood 116 (21) , p. 1125.

Burnett, Alan Kenneth, Hills, Robert Kerrin, Green, C., Jenkinson, S., Koo, K., Patel, Y., Guy, Carol, Gilkes, Amanda F., Milligan, D.W., Goldstone, A.H., Prentice, A.G., Wheatley, K., Linch, D. C. and Gale, R. E. 2010. The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA. Blood 115 (5) , pp. 948-956. 10.1182/blood-2009-08-236588

Burnett, Alan Kenneth, Hills, Robert Kerrin, Green, Claire, Jenkinson, Sarah, Koo, Kenneth, Patel, Yashma, Guy, Carol, Gilkes, Amanda F., Milligan, Donald W., Goldstone, Anthony. H., Prentice, Archibald G., Wheatley, Keith, Linch, David C. and Gale, Rosemary E. 2010. The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA. Blood 115 (5) , pp. 948-956. 10.1182/blood-2009-08-236588

McLornan, P., McMullin, M. F., Mills, Kenneth Ian, Hills, Robert Kerrin, Gilkes, Amanda F., Burnett, Alan Kenneth, Johnston, P. and Longley, D. B. 2009. The prognostic role of C-Flip in AML [Abstract]. Haematologica 94 (S2) , p. 108.

Gale, Rosemary, Hills, Robert Kerrin, Green, Claire, Patel, Yashma, Gilkes, Amanda F., Lazenby, Michelle, Wheatley, Keith, Linch, David C. and Burnett, Alan Kenneth 2008. The impact of FLT3-ITD and NPM1 Mutational Status on the outcome of ATRA therapy in patients with Non-APL AML: results of the UK MRC AML12 trial [Abstract]. Blood -New York- 112 (11) , p. 207.

Al Shaer, Laila, Walsby, Elisabeth Jane, Gilkes, Amanda F., Tonks, Amanda Jayne, Walsh, Valerie, Mills, Kenneth Ian, Burnett, Alan Kenneth and Rowntree, Clare 2008. Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling. British Journal of Haematology 141 (4) , pp. 483-493. 10.1111/j.1365-2141.2008.07053.x

Jenkins, Christopher, Hewamana, Saman, Gilkes, Amanda F., Neelakantan, Sundar, Crooks, Peter, Mills, Ken, Pepper, Christopher John and Burnett, Alan Kenneth 2008. Nuclear factor-kappaB as a potential therapeutic target for the novel cytotoxic agent LC-1 in acute myeloid leukaemia. British Journal of Haematology 143 (5) , pp. 661-671. 10.1111/j.1365-2141.2008.07392.x

Guy, Carol, Gilkes, Amanda F., Gale, Rosemary, Linch, David C., Hills, Robert Kerrin and Burnett, Alan Kenneth 2008. The impact of MN1 over-expression on the outcome of younger patients with AML treated with intensive chemotherapy with or without ATRA therapy [Abstract]. Blood -New York- 112 (11) , p. 1023.

Tonks, Alex, Pearn, Lorna, Musson, Megan, Gilkes, Amanda F., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2007. Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia. Leukemia 21 (12) , pp. 2495-2505. 10.1038/sj.leu.2404961

Walsby, Elisabeth Jane, Gilkes, Amanda Frances, Tonks, Alex, Darley, Richard Lawrence and Mills, Kenneth Ian 2007. FUS expression alters the differentiation response to all-trans retinoic acid in NB4 and NB4R2 cells. British Journal of Haematology 139 (1) , pp. 94-97. 10.1111/j.1365-2141.2007.06756.x

Knapper, Steven, Mills, Kenneth I., Gilkes, Amanda F., Austin, Steve J., Walsh, Valerie and Burnett, Alan K. 2006. The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases. Blood 108 (10) , pp. 3494-3503. 10.1182/blood-2006-04-015487

Guinn, Barbara-ann, Gilkes, Amanda F., Mufti, Ghulam J., Burnett, Alan Kenneth and Mills, Kenneth Ian 2006. The tumour antigens RAGE-1 and MGEA6 are expressed more frequently in the less lineage restricted subgroups of presentation acute myeloid leukaemia. British Journal of Haematology 134 (2) , pp. 238-239. 10.1111/j.1365-2141.2006.06135.x

Guinn, Barbara-ann, Gilkes, Amanda F., Woodward, Eleanor, Westwood, Nigel B., Mufti, Ghulam J., Linch, David, Burnett, Alan Kenneth and Mills, Kenneth Ian 2005. Microarray analysis of tumour antigen expression in presentation acute myeloid leukaemia. Biochemical and Biophysical Research Communications 333 (3) , pp. 703-713. 10.1016/j.bbrc.2005.05.161

Gale, Rosmary E., Hills, Robert Kerrin, Pizzey, Arnold R., Kottaridis, Panagiotis D., Swirsky, David, Gilkes, Amanda F., Nugent, Elizabeth, Mills, Kenneth I., Wheatley, Keith, Solomon, Ellen, Burnett, Alan Kenneth, Linch, David C. and Grimwade, David 2005. Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia. Blood 106 (12) , pp. 3768-3776. 10.1182/blood-2005-04-1746

Guinn, B. A., Evely, R. S., Walsh, V., Gilkes, Amanda, Burnett, Alan Kenneth and Mills, K. I. 2000. An in vivo and in vitro comparison of the effects of b2-a2 and b3-a2 p210BCR-ABL splice variants on murine 32D cells. Leukemia and Lymphoma 37 (3-4) , pp. 393-404. 10.3109/10428190009089440

Mills, K. I., Walsh, V., Gilkes, Amanda F., Sweeney, Marion Carol, Mirza, T., Woodgate, Louise, Brown, G. and Burnett, Alan Kenneth 2000. High FUS/TLS expression in acute myeloid leukaemia samples. British Journal of Haematology 108 (2) , pp. 316-321. 10.1046/j.1365-2141.2000.01883.x

Mills, Kenneth Ian, Woodgate, Louise, Gilkes, Amanda F., Walsh, V., Sweeney, Marion Carol, Brown, G. and Burnett, Alan Kenneth 1999. Inhibition of mitochondrial function in HL60 cells is associated with an increased apoptosis and expression of CD14. Biochemical and Biophysical Research Communications 263 (2) , pp. 294-300. 10.1006/bbrc.1999.1356

Woodgate, Louise J., Walker, E. J., Gilkes, Amanda F., Walsh, V., Sweeney, Marion Carol, Mills, Kenneth I. and Burnett, Alan 1999. Lovastatin in combination with ATRA may be a potential therapy for leukaemia [Abstract]. British Journal of Haematology 105 (Sup.) , p. 74.

Mills, Kenneth Ian, Walsh, Valerie, Gilkes, Amanda F., Woodgate, Louise J. and Burnett, Alan Kenneth 1999. Inhibitors of mitochondrial function in HL60 cells induce CD14 prior to CD38 [Abstract]. British Journal of Haematology 105 (Sup.1) , p. 77.

Robinson, L. G., Austin, Steve, Owen-Jones, Catrin Eleri, Kell, J., Gilkes, Amanda, Dann, E., Mills, K. and Burnett, Alan Kenneth 1999. Altered gene expression in 32D cells expressing the AML1A gene or AML1-ETO fusion gene. British Journal of Haematology 105 (Supp1) , p. 103.

Mills, Kenneth Ian, Gilkes, Amanda, Sweeney, Marion, Choudhry, M. A., Woodgate, Louise, Bunce, C. M., Brown, G. and Burnett, Alan Kenneth 1998. Identification of a retinoic acid responsive aldoketoreductase expressed in HL60 leukaemic cells. FEBS Letters 440 (1-2) , pp. 158-162. 10.1016/s0014-5793(98)01435-5

Mills, K. I., Walsh, V., Gilkes, Amanda, Woodgate, Louise, Brown, G. and Burnett, Alan Kenneth 1998. Identification of transcription factors expressed during ATRA-induced neutrophil differentiation of HL60 cells. British Journal of Haematology 103 (1) , pp. 87-92. 10.1046/j.1365-2141.1998.00947.x

Woodgate, Louise J., Walker, E. J., Gilkes, Amanda F., Walsh, V., Mills, Kenneth Ian and Burnett, Alan Kenneth 1998. Lovastatin in combination with ATRA partially overcomes the block in ATRA responsiveness of the serum independent HL60 cell line [Abstract]. British Journal of Haematology 101 (S) , p. 34.

Woodgate, Louise J., Gilkes, Amanda F., Newsway, Vicky, Mills, K. I. and Burnett, Alan Kenneth 1998. Mitochondrial inhibitors may act as promoters of differentiation in the serum free HL60 cell line [Abstract]. British Journal of Haematology 101 (S) , p. 34.

Mills, KI, Walsh, Val, Guinn, B. A., Gilkes, Amanda F., Davies, C., Lee Jones, L., Goringe, A., Evely, R. S. and Burnett, Alan Kenneth 1997. Increased tissue infiltration and decreased survival of SCID mice injected with 32D cells expressing BCR-ABL mRNA may be related to increased expression of CD44 and RHAMM [Abstract]. Blood 90 (10) , p. 4005.

Woodgate, Louise, Gilkes, Amanda F., Newsway, V., Mills, Kenneth Ian and Burnett, Alan Kenneth 1997. Mitochondrial inhibitors as differentiation agents in the myeloid HL60 cell line [Abstract]. Blood 90 (10) , p. 3801.

Evely, R. S., Darley, Richard Lawrence, Gilkes, Amanda F., Goringe, A., Mirza, T. and Burnett, Alan Kenneth 1996. In-vivo modelling of myeloid malignancies using severe combined immunodeficient (SCID) mice [Abstract]. British Journal of Haematology 93 , p. 205.

This list was generated on Thu Oct 17 05:25:53 2019 BST.