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Number of items: 10.

Johnson, Charlotte E., Dunlop, Elaine A., Seifan, Sara, McCann, Henry D., Hay, Trevor, Parfitt, Geraint J., Jones, Ashley T., Giles, Peter J., Shen, Ming H., Sampson, Julian R., Errington, Rachel J., Davies, David Mark and Tee, Andrew R. 2018. Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir−bortezomib therapy to intensify endoplasmic reticulum stress-induced cell death. Oncogene 37 , pp. 5913-5925. 10.1038/s41388-018-0381-2
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Johnson, Charlotte, Hunt, David K., Wiltshire, Marie, Herbert, Terry P., Sampson, Julian Roy, Errington, Rachel J., Davies, David Mark and Tee, Andrew 2014. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine. Molecular Oncology 9 (3) , pp. 675-688. 10.1016/j.molonc.2014.11.005
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Yan, Ming, Gingras, Marie-Claude, Dunlop, Elaine, Nouët, Yann, Dupuy, Fanny, Jalali, Zahra, Possik, Elite, Coull, Barry J., Kharitidi, Dmitri, Dydensborg, Anders Bondo, Faubert, Brandon, Kamps, Miriam, Sabourin, Sylvie, Preston, Rachael S., Davies, David, Roughead, Taren, Chotard, Laëtitia, van Steensel, Maurice A.M., Jones, Russell, Tee, Andrew and Pause, Arnim 2014. The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation. The Journal of Clinical Investigation 124 (6) , pp. 2640-2650. 10.1172/JCI71749
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Davies, David Mark, de Vries, P. J., Johnson, S. R., McCartney, Deborah L., Cox, J. A., Serra, A. L., Watson, P. C., Howe, C. J., Doyle, T., Pointon, K., Cross, J. J., Tattersfield, A. E., Kingswood, J. C. and Sampson, Julian Roy 2011. Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial. Clinical Cancer Research 17 (12) , pp. 4071-4081. 10.1158/1078-0432.CCR-11-0445

Dunlop, Elaine A., Dodd, Kayleigh M., Land, Stephen C, Davies, Peter A., Martins, Nicole, Stuart, Helen, McKee, Shane, Kingswood, Chris, Saggar, Anand, Corderio, Isabel, Medeira, Ana Maria Duarte, Kingston, Helen, Sampson, Julian Roy, Davies, David Mark and Tee, Andrew 2011. Determining the pathogenicity of patient-derived TSC2 mutations by functional characterization and clinical evidence. European Journal of Human Genetics 19 (7) , pp. 789-795. 10.1038/ejhg.2011.38

Preston, Rachael S., Philp, A., Claessens, T., Gijezen, L., Dydensborg, A. B., Dunlop, Elaine A., Harper, Katy T., Brinkhuizen, T., Menko, F. H., Davies, David Mark, Land, S. C., Pause, A., Baar, K., van Steensel, M. A. M. and Tee, Andrew 2011. Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility. Oncogene 30 (10) , pp. 1159-1173. 10.1038/onc.2010.497

Davies, David Mark 2011. mTOR inhibition as a therapeutic strategy in tuberous sclerosis or sporadic lymphangioleiomyomatosis. PhD Thesis, Cardiff University.
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Davies, David Mark and Sampson, Julian Roy 2010. Small-molecule signal-transduction inhibitors: targeted therapeutic agents for single-gene disorders. Journal of Medical Genetics 47 (3) , pp. 145-149. 10.1136/jmg.2008.064113

Davies, David Mark, Johnson, Simon R., Tattersfield, Anne E., Kingswood, J. Chris, Cox, Jane A., McCartney, Deborah L., Doyle, Tim, Elmslie, Frances, Saggar, Anand, de Vries, Petrus J. and Sampson, Julian Roy 2008. Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis [Letter]. New England Journal of Medicine 358 (2) , pp. 200-203. 10.1056/NEJMc072500

Clarke, Angus John and Davies, David Mark 2007. Clinical genetics. In: Levene, M. I. ed. MRCPCH MasterCourse, Vol. 1. Edinburgh: Churchill Livingstone (Elsevier), pp. 86-100.

This list was generated on Sat Aug 24 05:04:22 2019 BST.