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Number of items: 53.

Morè, Lorenzo, Lauterborn, Julie C., Papaleo, Francesco and Brambilla, Riccardo 2020. Enhancing cognition through pharmacological and environmental interventions: Examples from preclinical models of neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews 110 , pp. 28-45. 10.1016/j.neubiorev.2019.02.003
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Bernardi, Rick E., Olevska, Anastasia, Morella, Ilaria, Fasano, Stefania, Santos, Eugenio, Brambilla, Riccardo and Spanagel, Rainer 2019. The inhibition of RasGRF2, but not RasGRF1, alters cocaine reward in mice. Journal of Neuroscience 39 (32) , pp. 6325-6338. 10.1523/JNEUROSCI.1120-18.2019

McWilliams, Thomas, Barini, Erica, Pohjolan-Pirhonen, Risto, Brooks, Simon, Singh, Francois, Burel, Sophie, Balk, Kristin, Kumar, Atul, Montava-Garriga, Lambert, Prescott, Alan, Hassoun, Sidi, Mouton-Liger, Francois, Ball, Graeme, Hills, Rachel, Knebel, Axel, Ulusoy, Ayse, Di Monte, Donato, Tamjar, Jevgenia, Antico, Odetta, Fears, Kyle, Smith, Laura, Brambilla, Riccardo, Palin, Eino, Valori, Miko, Eerola-Rautio, Johanna, Tienari, Pentti, Corti, Olga, Dunnett, Stephen, Ganley, Ian, Suomalainen, Anu and Muqit, Miratul 2018. Phosphorylation of Parkin at Serine65 is essential for its activation in vivo. Open Biology 8 , 180108. 10.1098/rsob.180108

Ruiz De Diego, Irene, Fasano, Stefania, Solis, Oscar, Garcia-Montes, Jose-Ruben, Brea, Jose, Loza, Maria, Brambilla, Riccardo and Rosario, Moratalla 2018. Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin. Scientific Reports 8 , 15381. 10.1038/s41598-018-33713-3

Pucilowska, Joanna, Vithayathil, Joseph, Pagani, Marco, Kelly, Caitlin, Karlo, Colleen, Robol, Camila, Morella, Ilaria, Alessandro, Gozzi, Brambilla, Riccardo and Landreth, Gary 2018. Pharmacological inhibition of ERK signaling rescues pathophysiology and behavioral phenotype associated with 16p11.2 chromosomal deletion in mice. Journal of Neuroscience 38 (30) , pp. 6640-6652. 10.1523/JNEUROSCI.0515-17.2018

Arcuri, Ludovico, Novello, Salvatore, Frassineti, Martina, Mercatelli, Daniela, Pisano, Clarissa Anna, Morella, Ilaria, Fasano, Stefania, Journigan, Blair V., Meyer, Michael E., Polgar, Willma E., Brambilla, Riccardo, Zaveri, Nurulain T. and Morari, Michele 2018. Anti-parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists. British Journal of Pharmacology 175 (5) , pp. 782-796. 10.1111/bph.14123

Iori, Valentina, Iyer, Anand M., Ravizza, Teresa, Beltrame, Luca, Paracchini, Lara, Marchini, Sergio, Cerovic, Milica, Hill, Cameron, Ferrari, Mariella, Zucchetti, Massimo, Molteni, Monica, Rossetti, Carlo, Brambilla, Riccardo, Steve White, H., D'Incalci, Maurizio, Aronica, Eleonora and Vezzani, Annamaria 2017. Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy. Neurobiology of Disease 99 , pp. 12-23. 10.1016/j.nbd.2016.12.007

Papale, Alessandro, d'Isa, Raffaele, Menna, Elisabetta, Cerovic, Milica, Solari, Nicola, Hardingham, Neil, Cambiaghi, Marco, Cursi, Marco, Barbacid, Mariano, Leocani, Letizia, Fasano, Stefania, Matteoli, Michela and Brambilla, Riccardo 2017. Severe intellectual disability and enhanced gamma-aminobutyric acidergic synaptogenesis in a novel model of rare RASopathies. Biological Psychiatry 81 (3) , pp. 179-192. 10.1016/j.biopsych.2016.06.016

Papale, Alessandro, Morella, Ilaria, Indrigo, Marzia Tina, Bernardi, Rick Eugene, Marrone, Livia, Marchisella, Francesca, Brancale, Andrea, Spanagel, Rainer, Brambilla, Riccardo and Fasano, Stefania 2016. Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors. eLife 5 , e17111. 10.7554/eLife.17111

Melgarejo da Rosa, Michelle, Yuanxiang, PingAn, Brambilla, Riccardo, Kreutz, Michael R. and Karpova, Anna 2016. Synaptic GluN2B/CaMKII-α signaling induces synapto-nuclear transport of ERK and Jacob. Frontiers in Molecular Neuroscience 9 , 66. 10.3389/fnmol.2016.00066

Rosas, Michela, Porru, Simona, Fenu, Sandro, Ruiu, Stefania, Peana, Alessandra T., Papale, Alessandro, Brambilla, Riccardo, Di Chiara, Gaetano and Acquas, Elio 2016. Role of nucleus accumbens μ opioid receptors in the effects of morphine on ERK1/2 phosphorylation. Psychopharmacology 233 (15-16) , 2943. 10.1007/s00213-016-4340-8

Trusel, Massimo, Cavaccini, Anna, Gritti, Marta, Greco, Barbara, Saintot, Pierre-Philippe, Nazzaro, Cristiano, Cerovic, Milica, Morella, Ilaria, Brambilla, Riccardo and Tonini, Raffaella 2015. Coordinated regulation of synaptic plasticity at striatopallidal and sriatonigral neurons orchestrates motor control. Cell Reports 13 (7) , pp. 1353-1365. 10.1016/j.celrep.2015.10.009

Barco, Angel, Brambilla, Riccardo and Rosenblum, Kobi 2015. Editorial. Neurobiology of Learning and Memory 124 , pp. 1-2. 10.1016/j.nlm.2015.08.001

Bastide, Matthieu F., Meissner, Wassilios G., Picconi, Barbara, Fasano, Stefania, Fernagut, Pierre-Olivier, Feyder, Michael, Francardo, Veronica, Alcacer, Cristina, Ding, Yunmin, Brambilla, Riccardo, Fisone, Gilberto, Jon Stoessl, A., Bourdenx, Mathieu, Engeln, Michel, Navailles, Sylvia, De Deurwaerdère, Philippe, Ko, Wai Kin D., Simola, Nicola, Morelli, Micaela, Groc, Laurent, Rodriguez, Maria-Cruz, Gurevich, Eugenia V., Quik, Maryka, Morari, Michele, Mellone, Manuela, Gardoni, Fabrizio and Tronci, Elisabetta 2015. Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease. Progress in Neurobiology 132 , pp. 96-168. 10.1016/j.pneurobio.2015.07.002

Bido, Simone, Solari, Nicola, Indrigo, Marzia, D'Antoni, Angela, Brambilla, Riccardo, Morari, Michele and Fasano, Stefania 2015. Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia. Annals of Clinical and Translational Neurology 2 (6) , pp. 662-678. 10.1002/acn3.202

Moncini, Silvia, Bonati, Maria Teresa, Morella, Ilaria, Ferrari, Luca, Brambilla, Riccardo and Riva, Paola 2015. Differential allelic expression of SOS1 and hyperexpression of the activating SOS1 c.755C variant in a Noonan syndrome family. European Journal of Human Genetics 23 (11) , pp. 1531-1537. 10.1038/ejhg.2015.20

Fossati, G., Morini, R., Corradini, I., Antonucci, F., Trepte, P., Edry, E., Sharma, V., Papale, Alessandro, Pozzi, D., Defilippi, P., Meier, J. C., Brambilla, Riccardo, Turco, E., Rosenblum, K., Wanker, E. E., Ziv, N. E., Menna, E. and Matteoli, M. 2015. Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis. Cell Death and Differentiation 22 , pp. 1425-1436. 10.1038/cdd.2014.227

Cerovic, Milica, Bagetta, Vincenza, Pendolino, Valentina, Ghiglieri, Veronica, Fasano, Stefania, Morella, Ilaria, Hardingham, Neil Robert, Heuer, Andreas, Papale, Alessandro, Marchisella, Francesca, Giampà, Carmela, Calabresi, Paolo, Picconi, Barbara and Brambilla, Riccardo 2015. Derangement of Ras-guanine nucleotide-releasing Factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia. Biological psychiatry 77 (2) , pp. 106-115. 10.1016/j.biopsych.2014.04.002

D'Isa, Raffaele, Brambilla, Riccardo and Fasano, Stefania 2014. Behavioral methods for the study of the Ras-ERK pathway in memory formation and consolidation: passive avoidance and novel object recognition tests. In: Trabalzini, Lorenza and Retta, Saverio Francesco eds. Ras Signaling: Methods and Protocols, Vol. 1120. Methods in Molecular Biology, Humana Press, pp. 131-156. (10.1007/978-1-62703-791-4_9)

Brambilla, Riccardo 2014. Preface. In: Brambilla, Riccardo ed. Viral Vector Approaches in Neurobiology and Brain Diseases, Neuromethods, vol. 82. Humana Press, vii-viii.

Brambilla, Riccardo, ed. 2014. Viral Vector Approaches in Neurobiology and Brain Diseases. Neuromethods, vol. 82. New York: Humana Press. 10.1007/978-1-62703-610-8

Papale, Alessandro and Brambilla, Riccardo 2014. Lentiviral vectors as research tools in neurobiology: design and production. In: Brambilla, Riccardo ed. Viral Vector Approaches in Neurobiology and Brain Diseases, Vol. 82. Neuromethods, Springer, pp. 3-10. (10.1007/978-1-62703-610-8_1)

Cerovic, Milica, d'Isa, Raffaele, Tonini, Raffaella and Brambilla, Riccardo 2013. Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum. Neurobiology of Learning and Memory 105 , pp. 63-80. 10.1016/j.nlm.2013.06.013

Solari, N., Bonito-Oliva, A., Fisone, G. and Brambilla, Riccardo 2013. Understanding cognitive deficits in Parkinson's disease: lessons from preclinical animal models. Learning & Memory 20 (10) , pp. 592-600. 10.1101/lm.032029.113

Millership, Steven, Ninkina, Natalia, Guschina, Irina, Norton, Jessica, Brambilla, Riccardo, Oort, Pieter J., Adams, Sean H., Dennis, Rowena J., Voshol, Peter J., Rochford, Justin J. and Buchman, Vladimir L. 2013. Correction for Millership et al., Increased lipolysis and altered lipid homeostasis protect -synuclein-null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 110 (13) , p. 5269. 10.1073/pnas.1302920110

Millership, Steven, Ninkina, Natalia, Guschina, Irina, Norton, Jessica, Brambilla, Riccardo, Oort, Pieter J., Adams, Sean H., Dennis, Rowena J., Voshol, Peter J., Rochford, Justin J. and Buchman, Vladimir L. 2012. Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 109 (51) , pp. 20943-20948. 10.1073/pnas.1210022110

Fisone, Gilberto and Brambilla, Riccardo 2012. Neuronal signaling and behavior. Frontiers in Behavioral Neuroscience 6 , 72. 10.3389/fnbeh.2012.00072

Marti, Matteo, Rodi, Donata, Li, Qin, Guerrini, Remo, Fasano, Stefania, Morella, Ilaria, Tozzi, Alessandro, Brambilla, Riccardo, Calabresi, Paolo, Simonato, Michele, Bezard, Erwan and Morari, Michele 2012. Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias. Journal of Neuroscience 32 (46) , pp. 16106-16119. 10.1523/JNEUROSCI.6408-11.2012

Fasano, Stefania and Brambilla, Riccardo 2011. Ras-ERK signaling in behavior: old questions and new perspectives. Frontiers in Behavioral Neuroscience 5 (79) , pp. 1-6. 10.3389/fnbeh.2011.00079

d’Isa, Raffaele, Clapcote, Steven, Voikar, Vootele, Wolfer, David, Giese, Karl Peter, Brambilla, Riccardo and Fasano, Stefania 2011. Mice lacking Ras-GRF1 show contextual fear conditioning but not spatial memory impairments: convergent evidence from two independently generated mouse mutant lines. Frontiers in Behavioral Neuroscience 5 (78) , pp. 1-11.

Silingardi, Davide, Angelucci, Andrea, De Pasquale, Roberto, Borsotti, Marco, Squitieri, Giovanni, Brambilla, Riccardo, Putignano, Elena, Pizzorusso, Tommaso and Berardi, Nicoletta 2011. ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex. Frontiers in Behavioral Neuroscience 5 , 84. 10.3389/fnbeh.2011.00084

Fasano, Stefania, Bezard, E., D'Antoni, A., Francardo, V., Indrigo, M., Qin, L., Dovero, S., Cerovic, Milica, Cenci, M. A. and Brambilla, Riccardo 2010. Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proceedings of the National Academy of Sciences 107 (50) , pp. 21824-21829. 10.1073/pnas.1012071107

Visigalli, I., Delai, S., Politi, L., Di Domenico, C., Cerri, F., Mrak, E., D'Isa, R., Ungaro, D., Stok, M., Sanvito, F., Mariani, E., Staszewsky, L., Godi, C., Russo, I., Cecere, F., del Carro, U., Rubinacci, A., Brambilla, Riccardo, Quattrini, A., Di Natale, P., Ponder, K., Naldini, L. and Biffi, A. 2010. Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model. Blood 116 (24) , pp. 5130-5139. 10.1182/blood-2010-04-278234

Indrigo, Marzia, Papale, Alessandro, Orellana, Daniel and Brambilla, Riccardo 2010. Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases. In: Seger, Rony ed. MAP Kinase Signaling Protocols, Methods in Molecular Biology, vol. 2. Springer, pp. 205-220. (10.1007/978-1-60761-795-2_12)

Fasano, Stefania, D'Antoni, A., Orban, P. C., Valjent, E., Putignano, E., Vara, H., Pizzorusso, T., Giustetto, M., Yoon, B., Soloway, P., Maldonado, R., Caboche, J. and Brambilla, Riccardo 2009. Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) controls activation of Extracellular Signal-Regulated Kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine. Biological Psychiatry 66 (8) , pp. 758-768. 10.1016/j.biopsych.2009.03.014

Fasano, Stefania, Pittenger, Christopher and Brambilla, Riccardo 2009. Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse. Frontiers in Behavioral Neuroscience 3 , 29. 10.3389/neuro.08.029.2009

Cunha, C., Angelucci, A., D'Antoni, A., Dobrossy, M. D., Dunnett, Stephen Bruce, Berardi, N. and Brambilla, Riccardo 2009. Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments. Neurobiology of Disease 33 (3) , pp. 358-368. 10.1016/j.nbd.2008.11.004

Papale, Alessandro, Cerovic, M. and Brambilla, Riccardo 2009. Viral vector approaches to modify gene expression in the brain. Journal of Neuroscience Methods 185 (1) , pp. 1-14. 10.1016/j.jneumeth.2009.08.013

Givogri, M. I., Bottai, D., Zhu, H. L., Fasano, Stefania, Lamorte, G., Brambilla, Riccardo, Vescovi, A., Wrabetz, L. and Bongarzone, E. 2008. Multipotential Neural Precursors Transplanted into the Metachromatic Leukodystrophy Brain Fail to Generate Oligodendrocytes but Contribute to Limit Brain Dysfunction. Developmental Neuroscience 30 , pp. 340-357. 10.1159/000150127

Marchi, M., D'Antoni, A., Formentini, I., Parra, R., Brambilla, Riccardo, Ratto, G. M. and Costa, M. 2008. The N-terminal domain of ERK1 accounts for the functional differences with ERK2. PLoS ONE 3 (12) , e3873. 10.1371/journal.pone.0003873

Capotondo, A., Cesani, M., Pepe, S., Fasano, Stefania, Gregori, S., Tononi, L., Venneri, M.A., Brambilla, Riccardo, Quattrini, A., Ballabio, A., Cosma, M. P., Naldini, L. and Biffi, A. 2007. Safety of Arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy. Human Gene Therapy 18 (9) , pp. 821-836. 10.1089/hum.2007.048

Ferguson, Susan M., Fasano, Stefania, Yang, Pengwei, Brambilla, Riccardo and Robinson, Terry E. 2006. Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity. Neuropsychopharmacology , pp. 2660-2668. 10.1038/sj.npp.1301014

Biffi, Alessandra, Capotondo, Alessia, Fasano, Stefania, del Carro, Ubaldo, Marchesini, Sergio, Azuma, Hisaya, Malaguti, Maria Chiara, Amadio, Stefano, Brambilla, Riccardo, Grompe, Markus, Bordignon, Claudio, Quattrini, Angelo and Naldini, Luigi 2006. Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice. The Journal of Clinical Investigation 116 (11) , pp. 3070-3082. 10.1172/JCI28873

Pittenger, Christopher, Fasano, Stefania, Mazzocchi-Jones, David Martin, Dunnett, Stephen Bruce, Kandel, Eric R. and Brambilla, Riccardo 2006. Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. Journal of Neuroscience 26 (10) , pp. 2808-2813. 10.1523/JNEUROSCI.5406-05.2006

Vantaggiato, Chiara, Formentini, Ivan, Bondanza, Attilio, Bonini, Chiara, Naldini, Luigi and Brambilla, Riccardo 2006. ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. Journal of Biology 5 (5) , 14. 10.1186/jbiol38

Croci, C., Fasano, Stefania, Superchi, D., Perani, L., Martellosio, A., Brambilla, Riccardo, Consalez, G. and Bongarzone, E. R. 2006. Cerebellar neurons and glial cells are transducible by lentiviral vectors without decrease of cerebellar functions. Developmental Neuroscience 28 (3) , pp. 216-222. 10.1159/000091919

Givogri, M. I., Galbiati, F., Fasano, Stefania, Amadio, S., Perani, L., Superchi, D., Morana, P., Del Carro, U., Marchesini, S., Brambilla, Riccardo, Wrabetz, L. and Bongarzone, E. 2006. Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy. Journal of Neuroscience 26 (12) , pp. 3109-3199. 10.1523/JNEUROSCI.4366-05.2006

Brambilla, Riccardo, Biffi, A., Bordignon, C. and Naldini, L. 2004. Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells. Journal of Clinical Investigation , pp. 1118-1129. 10.1172/JCI200419205

Clapcott, Steven J., Peters, Josephine, Orban, Paul C., Brambilla, Riccardo and Graham, Chris F. 2003. Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation. Mammalian Genome 14 (8) , pp. 495-505. 10.1007/s00335-002-2258-4

Brambilla, Riccardo 2003. Targeting Ras/ERK signaling in the striatum: will it help? Molecular Psychiatry 8 (4) , pp. 366-368. 10.1038/sj.mp.4001291

Mazzuccchelli, Cristina, Vantaggiato, Chiara, Ciamei, Alessandro, Fasano, Stefania, Pakhotin, Pavel, Krezel, Wojciech, Welzl, Hans, Wolfer, David P., Pages, Gilles, Valverde, Olga, Marowsky, Anne, Porrazzo, Annamaria, Orban, Paul C., Maldonado, Rafael, Ehrengruber, Markus U.Anne, Cestari, Vincenzo, Lipp, Hans-Peter, Chapman, Paul Frederick James, Pouyssegur, Jacques and Brambilla, Riccardo 2002. Knockout of ERK1 MAP Kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron , pp. 807-820. 10.1016/S0896-6273(02)00716-X

Fasano, Stephania and Brambilla, Riccardo 2002. Cellular mechanisms of striatum-dependent behavioral plasticity and drug addiction. Current Molecular Medicine 2 (7) , pp. 649-665. 10.2174/1566524023362005

Tonini, Raffaella, Fanceschetti, Silvana, Parolaro, Daniela, Sala, Mariaelvina, Mancinelli, Enzo, Tininini, Silvia, Brusetti, Ronny, Sancini, Giulio, Brambilla, Riccardo, Martegani, Enzo, Sturani, Emmapaola and Zippel, Renata 2001. Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability. Molecular and Cellular Neuroscience 18 (6) , pp. 691-701. 10.1006/mcne.2001.1050

This list was generated on Wed Apr 1 04:30:24 2020 BST.

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