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Vlachava, Virginia-Maria, Murrell, Isa, Zhuang, Lihui, Aicheler, Rebecca J., Lim, Eleanor, Miners, Kelly L., Ladell, Kristin, Suárez, Nicolás M., Price, David A., Davison, Andrew J., Wilkinson, Gavin W.G., Wills, Mark R., Weekes, Michael P., Wang, Eddie C.Y. and Stanton, Richard J.
2021.
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus.
Journal of Clinical Investigation
131
(4)
, e139296.
10.1172/JCI139296
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Kasatskaya, Sofya A., Ladell, Kristin, Egorov, Evgeniy S., Miners, Kelly L., Davydov, Alexey N., Metsger, Maria, Staroverov, Dmitry B., Matveyshina, Elena K., Shagina, Irina A., Mamedov, Ilgar Z., Izraelson, Mark, Shelyakin, Pavel V., Britanova, Olga V., Price, David A. and Chudakov, Dmitriy M.
2020.
Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs.
eLife
9
, e57063.
10.7554/eLife.57063
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Ahmed, Raya, Miners, Kelly L., Lahoz-Beneytez, Julio, Jones, Rhiannon E., Roger, Laureline, Baboonian, Christina, Zhang, Yan, Wang, Eddie C. Y., Hellerstein, Marc K., McCune, Joseph M., Baird, Duncan M., Price, David A., Macallan, Derek C., Asquith, Becca and Ladell, Kristin
2020.
CD57+ Memory T Cells Proliferate In Vivo.
Cell Reports
33
(11)
, 108501.
10.1016/j.celrep.2020.108501
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Pearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly-Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E., Ladell, Kristin, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A., Tunger, Antje, Schmitz, Marc, Miles, John J, Lahoud, Mireille H and Radford, Kristen J
2020.
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells.
Clinical and Translational Immunology
9
10.1002/cti2.1141
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Appanna, Gautham D, Pembroke, Thomas P I, Miners, Kelly L, Price, David A, Gallimore, Awen M, Ladell, Kristin and Godkin, Andrew J
2019.
Rituximab depletion of intrahepatic B cells to control refractory hepatic autoimmune overlap syndrome.
QJM: An International Journal of Medicine
112
(10)
, pp. 793-795.
10.1093/qjmed/hcz161
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Wong, Emily B., Gold, Marielle C., Meermeier, Erin W., Xulu, Bongiwe Z., Khuzwayo, Sharon, Sullivan, Zuri A., Mahyari, Eisa, Rogers, Zoe, Kløverpris, Hénrik, Sharma, Prabhat K., Worley, Aneta H., Lalloo, Umesh, Baijnath, Prinita, Ambaram, Anish, Naidoo, Leon, Suleman, Moosa, Madansein, Rajhmun, McLaren, James E., Ladell, Kristin, Miners, Kelly L., Price, David A., Behar, Samuel M., Nielsen, Morten, Kasprowicz, Victoria O., Leslie, Alasdair, Bishai, William R., Ndung'u, Thumbi and Lewinsohn, David M.
2019.
TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.
Communications Biology
2
(1)
, -.
10.1038/s42003-019-0442-2
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Mohammed, Rebar N., Wehenkel, Sophie C., Galkina, Elena V., Yates, Emma-Kate, Preece, Graham, Newman, Andrew, Watson, H. Angharad, Ohme, Julia, Bridgeman, John S., Durairaj, Ruban R. P., Moon, Owen R., Ladell, Kristin, Miners, Kelly L., Dolton, Garry, Troeberg, Linda, Kashiwagi, Masahide, Murphy, Gillian, Nagase, Hideaki, Price, David A., Matthews, R. James, Knauper, Vera and Ager, Ann
2019.
ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Scientific Reports
9
, 5487.
10.1038/s41598-019-41811-z
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McLaren, James, Clement, Mathew, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J., Ladell, Kristin, Price, David A. and Humphreys, Ian R.
2019.
IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea.
Journal of Immunology
202
(3)
, pp. 943-955.
10.4049/jimmunol.1701757
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Boelen, Lies, Debebe, Bisrat, Silveira, Marcos, Salam, Arafa, Makinde, Julia, Roberts, Chrissy h., Wang, Eddie C. Y., Frater, John, Gilmour, Jill, Twigger, Katie, Ladell, Kristin, Miners, Kelly L., Jayaraman, Jyothi, Traherne, James A., Price, David A., Qi, Ying, Martin, Maureen P., Macallan, Derek C., Thio, Chloe L., Astemborski, Jacquie, Kirk, Gregory, Donfield, Sharyne M., Buchbinder, Susan, Khakoo, Salim I., Goedert, James J., Trowsdale, John, Carrington, Mary, Kollnberger, Simon and Asquith, Becca 2018. Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1. Science Immunology 3 (29) , eaao2892. 10.1126/sciimmunol.aao2892 |
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Costa del Amo, Pedro, Beneytez, Julio Lahoz, Boelen, Lies, Ahmed, Raya, Miners, Kelly L., Zhang, Yan, Roger, Laureline, Jones, Rhiannon E., Marraco, Silvia A. Fuertes, Speiser, Daniel E., Baird, Duncan M., Price, David A., Ladell, Kristin, Macallan, Derek and Asquith, Becca 2018. Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness. PLoS Biology 16 (6) , e2005523. 10.1371/journal.pbio.2005523 |
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Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., McLaren, James E., Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A., Van Rhijn, Ildiko, Moody, D. Branch and Rossjohn, Jamie
2018.
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Nature Immunology
19
, pp. 397-406.
10.1038/s41590-018-0065-7
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McCully, Michelle L., Ladell, Kristin, Andrews, Robert, Jones, Rhiannon E., Miners, Kelly L., Roger, Laureline, Baird, Duncan M., Cameron, Mark J., Jessop, Zita M., Whitaker, Iain S., Davies, Eleri L., Price, David A. and Moser, Bernhard
2018.
CCR8 expression defines tissue-resident memory T cells in human skin.
Journal of Immunology
200
(5)
, pp. 1639-1650.
10.4049/jimmunol.1701377
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Lissina, Anna, McLaren, James E., Ilander, Mette, Andersson, Emma I., Lewis, Catherine S., Clement, Mathew, Herman, Andrew, Ladell, Kristin, Llewellyn-Lacey, Sian, Miners, Kelly L., Gostick, Emma, Melenhorst, J. Joseph, Barrett, A. John, Price, David A., Mustjoki, Satu and Wooldridge, Linda 2018. Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions. Scientific Reports 8 (1) , 2534. 10.1038/s41598-017-18062-x |
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Van Braeckel-Budimir, Natalija, Gras, Stephanie, Ladell, Kristin, Josephs, Tracy M., Pewe, Lecia, Urban, Stina L., Miners, Kelly L., Farenc, Carine, Price, David A., Rossjohn, Jamie and Harty, John T.
2017.
A T cell receptor locus harbors a malaria-specific immune response gene.
Immunity
47
(5)
, 835-847.e4.
10.1016/j.immuni.2017.10.013
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Culshaw, Abigail, Ladell, Kristin, Gras, Stephanie, McLaren, James E., Miners, Kelly L., Farenc, Carine, van den Heuvel, Heleen, Gostick, Emma, Dejnirattisai, Wanwisa, Wangteeraprasert, Apirath, Duangchinda, Thaneeya, Chotiyarnwong, Pojchong, Limpitikul, Wannee, Vasanawathana, Sirijitt, Malasit, Prida, Dong, Tao, Rossjohn, Jamie, Mongkolsapaya, Juthathip, Price, David A. and Screaton, Gavin R.
2017.
Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response.
Nature Immunology
18
, pp. 1228-1237.
10.1038/ni.3850
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Murrell, Isa, Bedford, Carmen, Ladell, Kristin, Miners, Kelly L., Price, David A., Tomasec, Peter, Wilkinson, Gavin W. G. and Stanton, Richard J.
2017.
The pentameric complex drives immunologically covert cell -cell transmission of wild-type human cytomegalovirus.
Proceedings of the National Academy of Sciences
114
(23)
, pp. 6104-6109.
10.1073/pnas.1704809114
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Ahmed, Raya, Roger, Laureline, Costa del Amo, Pedro, Miners, Kelly L., Jones, Rhiannon E., Boelen, Lies, Fali, Tinhinane, Elemans, Marjet, Zhang, Yan, Appay, Victor, Baird, Duncan M., Asquith, Becca, Price, David A., Macallan, Derek C. and Ladell, Kristin 2016. Human stem cell-like memory T cells are maintained in a state of dynamic flux. Cell Reports 17 (11) , pp. 2811-2818. 10.1016/j.celrep.2016.11.037 |
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Watson, H. Angharad, Dolton, Garry Michael, Ohme, Julia, Ladell, Kristin Ingrid, Vigar, Miriam, Wehenkel, Sophie, Hindley, James, Mohammed, Rebar, Miners, Kelly, Luckwell, Rhys A, Price, David, Matthews, R James and Ager, Ann 2016. Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1. Immunology and Cell Biology 94 (8) 10.1038/icb.2016.45 |
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Caucheteux, Stephan M., Mitchell, John P., Ivory, Matthew O., Hirosue, Sachiko, Hakobyan, Svetlana, Dolton, Garry, Ladell, Kristin, Miners, Kelly, Price, David A., Kan-Mitchell, June, Sewell, Andrew K., Nestle, Frank, Moris, Arnaud, Karoo, Richard O., Birchall, James C., Swartz, Melody A., Hubbel, Jeffrey A., Blanchet, Fabien P. and Piguet, Vincent
2016.
Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1.
Journal of Investigative Dermatology
136
(6)
, pp. 1172-1181.
10.1016/j.jid.2016.01.033
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Pearson, James A., Thayer, Terri C., McLaren, James E., Ladell, Kristin, De Leenheer, Evy, Phillips, Amy, Davies, Joanne, Kakabadse, Dimitri, Miners, Kelly, Morgan, Peter, Wen, Li, Price, David A. and Wong, F. Susan 2016. Proinsulin expression shapes the TCR repertoire but fails to control the development of low-avidity insulin-reactive CD8+ T cells. Diabetes 65 (6) , pp. 1679-1689. 10.2337/db15-1498 |
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Holland, Christopher J., Dolton, Garry M., Scurr, Martin, Ladell, Kristin, Schauenburg, Andrea J., Miners, Kelly, Madura, Florian, Sewell, Andrew K., Price, David A., Cole, David K. and Godkin, Andrew J.
2015.
Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers.
Journal of Immunology
195
(12)
, pp. 5827-5836.
10.4049/jimmunol.1402787
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Neller, Michelle A., Ladell, Kristin Ingrid, McLaren, James Edward, Matthews, Katherine K., Gostick, Emma, Pentier, Johanne, Dolton, Garry Michael, Schauenburg, Andrea J. A., Koning, Dan, Fontaine Costa, Ana Isabel C. A., Watkins, Thomas S., Venturi, Vanessa, Smith, Corey, Khanna, Rajiv, Miners, Kelly Louise, Clement, Mathew, Wooldridge, Linda, Cole, David, van Baarle, Debbie, Sewell, Andrew K., Burrows, Scott R., Price, David and Miles, John James 2015. Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics. Immunology and Cell Biology 93 , pp. 625-633. 10.1038/icb.2015.17 |
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Willis, G. R., Connolly, K., Ladell, K., Davies, T. S., Guschina, I. A., Ramji, D., Miners, K., Price, D. A., Clayton, A., James, P. E. and Rees, D. A. 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12) , pp. 2756-2763. 10.1093/humrep/deu281 |
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Pearson, James, Thayer, T. C., McLaren, James Edward, Miners, Kelly Louise, Ladell, Kristin Ingrid, Price, David and Wong, Florence Susan 2014. Analysis of the repertoire of insulin-reactive CD8(+) T cells [Abstract]. Immunology 143 (S2) , p. 152. 10.1111/imm.12406 |
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Stanton, Richard J., Prod'homme, Virginie, Purbhoo, Marco A., Moore, Melanie, Aicheler, Rebecca J., Heinzmann, Marcus, Bailer, Susanne M., Haas, Jürgen, Antrobus, Robin, Weekes, Michael P., Lehner, Paul J., Vojtesek, Borivoj, Miners, Kelly L., Man, Stephen, Wilkie, Gavin S., Davison, Andrew J., Wang, Eddie C. Y., Tomasec, Peter and Wilkinson, Gavin W. G.
2014.
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.
Cell Host and Microbe
16
(2)
, pp. 201-214.
10.1016/j.chom.2014.07.005
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Melamed, Anat, Witkover, Aviva D., Laydon, Daniel J., Brown, Rachael, Ladell, Kristin, Miners, Kelly, Rowan, Aileen G., Gormley, Niall, Price, David, Taylor, Graham P., Murphy, Edward L. and Bangham, Charles R. M. 2014. Clonality of HTLV-2 in natural infection. PLoS Pathogens 10 (3) , e1004006. 10.1371/journal.ppat.1004006 |
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Bridgeman, John S., Ladell, Kristin Ingrid, Sheard, V. E., Miners, Kelly Louise, Hawkins, R. E., Price, David and Gilham, D. E. 2014. CD3ζ-based chimeric antigen receptors mediate T cell activation viacis- andtrans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy. Clinical and Experimental Immunology 175 (2) , pp. 258-267. 10.1111/cei.12216 |
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van den Berg, Hugo A., Ladell, Kristin, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew, Cole, David, Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Bridgeman, John S. and Price, David 2013. Cellular-level versus receptor-level response threshold hierarchies in T-cell activation. Frontiers in Immunology 4 , 250. 10.3389/fimmu.2013.00250 |
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Nunes, Claudia Trindade, Miners, Kelly Louise, Dolton, Garry Michael, Pepper, Christopher John, Fegan, Christopher Daniel, Mason, Malcolm David and Man, Stephen Tzekwung 2011. A novel tumor antigen derived from enhanced degradation of Bax protein in human cancers. Cancer Research 71 (16) , pp. 5435-5444. 10.1158/0008-5472.CAN-11-0393 |
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Campo, M. S., Graham, S. V., Cortese, M. S., Ashrafi, G. H., Araibi, E. H., Dornan, E. S., Miners, Kelly Louise, Nunes, Claudia Trindade and Man, Stephen Tze Kwung 2010. HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells. Virology 407 (1) , pp. 137-142. 10.1016/j.virol.2010.07.044 |
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