ORCA
Online Research @ Cardiff

Browse by Current Cardiff authors

Number of items: 17.

Da'as, Sahar I., Thanassoulas, Angelos, Calver, Brian, Beck, Konrad, Salem, Rola, Saleh, Alaaeldin, Kontogianni, Iris, Al-Maraghi, Ali, Nasrallah, Gheyath K., Safieh-Garabedian, Bared, Toft, Egon, Nounesis, George, Lai, F A and Nomikos, Michail 2019. Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish. Annals of the New York Academy of Sciences 1448 (1) , pp. 19-29. 10.1111/nyas.14033
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Daas, Sahar I, Fakhro, Khalid, Thanassoulas, Angelos, Krishnamoorthy, Navaneethakrishnan, Saleh, Alaaeldin, Calver, Brian L, Safiehgarabedian, Bared, Toft, Egon, Nounesis, George, Lai, Anthony and Nomikos, Michail 2018. Hypertrophic cardiomyopathy-linked variants of cardiac myosin binding protein C3 display altered molecular properties and actin interaction. Biochemical Journal 475 (24) , pp. 3933-3948. 10.1042/BCJ20180685
Item availability restricted.

Calver, Brian 2018. The role of calmodulin in the regulation of calcium signalling proteins in health and disease. PhD Thesis, Cardiff University.

Item availability restricted.

Nomikos, Michail, Stamatiadis, Panagiotis, Sanders, Jessica Rose, Beck, Konrad, Calver, Brian Lewis, Buntwal, Luke, Lofty, Morgan, Sideratou, Zili, Swann, Karl and Lai, Francis Anthony 2017. Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ. Biochemical Journal 474 (6) , pp. 1003-1016. 10.1042/BCJ20161057

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad, Theodoridou, Maria, Kew, Jasmine, Kashir, Junaid, Calver, Brian Lewis, Matthews, Emily, Rizkallah, Pierre, Sideratou, Zili, Nounesis, George and Lai, Francis Anthony 2016. Mutations in PLCd1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function. FEBS Journal 283 (24) , pp. 4502-4514. 10.1111/febs.13939

Nomikos, Michail, Sanders, Jessica Rose, Parthimos, Dimitris, Buntwal, Luke, Calver, Brian Lewis, Stamatiadis, Panagiotis, Smith, Adrian, Clue, Matthew, Sideratou, Zili, Swann, Karl and Lai, Francis Anthony 2015. Essential role of the EF-hand domain in targeting sperm phospholipase Cζ to membrane phosphatidylinositol 4,5-bisphosphate (PIP2). Journal of Biological Chemistry 290 (49) , pp. 29519-29530. 10.1074/jbc.M115.658443

Vassilakopoulou, Vyronia, Calver, Brian, Thanassoulas, Angelos, Beck, Konrad, Hu, Handan, Buntwal, Luke, Smith, Adrian, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda, Livaniou, Evangelia, Nounesis, George, Lai, Francis and Nomikos, Michail 2015. Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease. Biochimica et Biophysica Acta (BBA) - General Subjects 1850 (11) , pp. 2168-2176. 10.1016/j.bbagen.2015.07.001

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad, Vassilakopoulou, Vyronia, Hu, Handan, Calver, Brian Lewis, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda Mary, Livaniou, Evangelia, Rizkallah, Pierre, Nounesis, George and Lai, Francis Anthony 2014. Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death. Febs Letters 588 (17) , pp. 2898-2902. 10.1016/j.febslet.2014.07.007

Nomikos, Michail, Theodoridou, Maria, Elgmati, Khalil, Parthimos, Dimitris, Calver, Brian, Buntwal, Luke, Nounesis, George, Swann, Karl and Lai, Francis 2014. Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca2+ oscillations required for mammalian oocyte activation. Molecular Human Reproduction 20 (6) , pp. 489-498. 10.1093/molehr/gau011

Theodoridou, Maria, Nomikos, Michail, Parthimos, Dimitris, Gonzalez-Garcia, J., Elgmati, K., Calver, Brian Lewis, Sideratou, Z., Nounesis, G., Swann, Karl and Lai, Francis Anthony 2013. Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization. Molecular Human Reproduction 19 (12) , pp. 852-864. 10.1093/molehr/gat070

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Nounesis, George, Swann, Karl and Lai, Francis Anthony 2011. Phospholipase C binding to PtdIns(4,5)P2 requires the XY-linker region. Journal of Cell Science 124 (15) , pp. 2582-2590. 10.1242/jcs.083485

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Cumbes, Bevan, Nounesis, George, Swann, Karl and Lai, Francis Anthony 2011. Male infertility-linked point mutation disrupts the Ca2+oscillation-inducing and PIP2hydrolysis activity of sperm PLCζ. Biochemical Journal 434 (2) , pp. 211-217. 10.1042/BJ20101772

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Cumbes, Bevan, Nounesis, George, Swann, Karl and Lai, Francis Anthony 2011. Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP2 hydrolysis activity of sperm PLCζ [Erratum]. The Biochemical Journal 435 (3) , p. 791.

Hubbard, Ruth Eleanor, O'Mahony, Marcella Sinead, Savva, George M., Calver, Brian Lewis and Woodhouse, Kenneth Walter 2009. Inflammation and frailty measures in older people. Journal of Cellular and Molecular Medicine 13 (9b) , pp. 3103-3109. 10.1111/j.1582-4934.2009.00733.x

Hubbard, Ruth Eleanor, O'Mahony, Marcella Sinead, Calver, Brian Lewis and Woodhouse, Kenneth Walter 2008. Nutrition, inflammation, and leptin levels in aging and frailty. Journal of the American Geriatrics Society 56 (2) , pp. 279-284. 10.1111/j.1532-5415.2007.01548.x

Hubbard, Ruth Eleanor, O'Mahony, Marcella Sinead, Calver, Brian Lewis and Woodhouse, Kenneth Walter 2008. Plasma esterases and inflammation in ageing and frailty. European Journal of Clinical Pharmacology 64 (9) , pp. 895-900. 10.1007/s00228-008-0499-1

White, Susan V., Calver, Brian Lewis, Newsway, Vicky, Wade, R., Patel, S., Bayer, Antony James and O'Mahony, Marcella Sinead 2005. Enzymes of drug metabolism during delirium. Age and Ageing 34 (6) , pp. 603-608. 10.1093/ageing/afi189

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