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Number of items: 28.

Williams, A and Thomas, Nia 2019. Reconstitution of ion channels from intracellular membranes and bacteria not amenable to conventional electrophysiological techniques. In: Roberts, Gordon and Watts, Anthony eds. Encyclopedia of Biophysics, Berlin, Germany: Springer, (10.1007/978-3-642-35943-9)

Bannister, Mark, Thomas, Nia, Markus, Sikkel, Mukherjee, Saptarshi, Chloe, Maxwell, Kenneth, MacLeod and George, Christopher H. 2016. Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia [Letter]. The Journal of Physiology 594 (21) , pp. 6431-6432. 10.1113/JP272497
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Handhle, Ahmed, Ormonde, Chloe E., Thomas, Nia Lowri, Bralesford, Catherine, Williams, Alan John, Lai, Francis Anthony and Zissimopoulos, Spyros 2016. Calsequestrin interacts directly with the cardiac ryanodine receptor luminal domain. Journal of Cell Science 129 (21) , pp. 3983-3988. 10.1242/jcs.191643
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Mukherjee, Saptarshi, Thomas, Nia Lowri and Williams, Alan John 2016. Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gating. Scientific Reports 6 , 34452. 10.1038/srep34452
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Bannister, Mark, Anita, Alvarez-Laviada, Thomas, Nia Lowri, Sammy, Mason, Sharon, Coleman, Christo, du Plessis, Abbygail, Moran, David, Neill-Hall, Hasnah, Osman, Mark, Bagley, Kenneth, MacLeod, George, Christopher H. and Williams, Alan 2016. Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor. British Journal of Pharmacology 173 (15) , pp. 2446-2459. 10.1111/bph.13521
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Bannister, Mark, Thomas, Nia Lowri, Sikkel, M. B., Mukherjee, Saptarshi, Maxwell, Chloe, MacLeod, Kenneth T., George, Christopher and Williams, Alan John 2015. The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2. Circulation Research 116 (8) , pp. 1324-1335. 10.1161/CIRCRESAHA.116.305347

Seidel, Monika, Thomas, Nia Lowri, Williams, Alan J., Lai, Francis Anthony and Zissimopoulos, Spyros 2015. Dantrolene rescues aberrant N-terminus intersubunit interactions in mutant pro-arrhythmic cardiac ryanodine receptors. Cardiovascular Research 105 (1) , pp. 118-128. 10.1093/cvr/cvu240
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Mukherjee, Saptarshi, Thomas, Nia Lowri and Williams, Alan John 2014. Insights into the gating mechanism of the ryanodine-modified human cardiac Ca2+- release channel (ryanodine receptor 2). Molecular Pharmacology 86 (3) , pp. 318-329. 10.1124/mol.114.093757

Zissimopoulos, Spyros, Viero, Cedric, Seidel, Monika, Cumbes, Bevan, White, Judith, Cheung, Iris, Stewart, Richard, Jeyakumar, Lois, Fleischer, Sidney, Mukherjee, Saptarshi, Thomas, Nia Lowri, Williams, Alan John and Lai, Francis Anthony 2013. Amino-terminus oligomerization regulates cardiac ryanodine receptor function. Journal of Cell Science n/a 10.1242/​jcs.133538

Euden, Joanne, Mason, Sammy, Viero, Cedric, Thomas, Nia Lowri and Williams, Alan John 2013. Investigations of the contribution of a putative glycine hinge to ryanodine receptor channel gating. Journal of Biological Chemistry 288 (23) , pp. 16671-16679. 10.1074/jbc.M113.465310
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Mukherjee, Saptarshi, Thomas, Nia Lowri and Williams, Alan John 2012. A mechanistic description of gating of the human cardiac ryanodine receptor in a regulated minimal environment. The Journal of General Physiology 140 (2) , pp. 139-158. 10.1085/jgp.201110706
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Thomas, Nia Lowri and Williams, Alan John 2012. Pharmacology of ryanodine receptors and Ca2+-induced Ca2+ release. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling 1 (4) , pp. 383-397. 10.1002/wmts.34

Viero, Cedric, Thomas, Nia Lowri, Euden, Joanne, Mason, Sammy A., George, Christopher H. and Williams, Alan J. 2012. Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level. Calcium Signaling, Advances in Experimental and Medical Biology, Dordrecht: Springer, pp. 183-215. (10.1007/978-94-007-2888-2_8)

Viero, Cedric, Thomas, Nia Lowri, Euden, Joanne, Mason, Sammy, George, Christopher H. and Williams, Alan John 2012. Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level. In: Islam, Md. Shahidul ed. Calcium Signaling, Advances in Experimental Medicine and Biology, vol. 740. Dordrecht: Springer, pp. 183-215. (10.1007/978-94-007-2888-2_8)

Thomas, Nia Lowri, Maxwell, Chloe, Mukherjee, Saptarshi and Williams, Alan John 2010. Ryanodine receptor mutations in arrhythmia: the continuing mystery of channel dysfunction. FEBS Letters 584 (10) , pp. 2153-2160. 10.1016/j.febslet.2010.01.057

Thomas, Nia Lowri, Maxwell, Chloe, Mukherjee, Saptarshi and Williams, Alan John 2010. Ryanodine receptor mutations in arrhythmia: The continuing mystery of channel dysfunction. Febs Journal 584 (10) , pp. 2153-2160. 10.1016/j.febslet.2010.01.057

Zissimopoulos, Spryos, Thomas, Nia Lowri, Jamaluddin, Wan W. and Lai, Francis Anthony 2009. FKBP12.6 binding of ryanodine receptors carrying mutations associated with arrhythmogenic cardiac disease. Biochemical Journal 419 (2) , pp. 273-278. 10.1042/BJ20082324

George, Christopher H., Rogers, Sarah Ann, Bertrand, Benedicte M.A., Tunwell, Richard E.A., Thomas, Nia Lowri, Steele, Derek S., Cox, Eryl Vanessa, Pepper, Christopher John, Hazeel, Carolyn Jean, Claycomb, William C. and Lai, Francis Anthony 2007. Alternative splicing of ryanodine receptors modulates cardiomyocyte Ca2+ signalling and susceptibility to apoptosis. Circulation Research 100 (6) , pp. 874-883. 10.1161/01.RES.0000260804.77807.cf

George, Christopher H., Jundi, Hala, Thomas, Nia Lowri, Fry, Debra L. and Lai, Francis Anthony 2007. Ryanodine receptors and ventricular arrhythmias: Emerging trends in mutations, mechanisms and therapies. Journal of Molecular and Cellular Cardiology 42 (1) , pp. 34-50. 10.1016/j.yjmcc.2006.08.115

Fry, Debra, Jundi, Hala, Thomas, Nia Lowri, Lai, Francis Anthony and George, Christopher H. 2007. Modulating intracellular Ca2+ signaling using recombinant fragments of the human cardiac ryanodine receptor (RyR2). Biophysical Journal , 260A-260A.

George, Christopher H., Thomas, Nia Lowri, Williams, A. J. and Lai, Francis Anthony 2007. Ryanodine receptor mutations in arrhythmias: advances in understanding the mechanisms of channel dysfunction. Biochemical Society Transactions 35 (5) , pp. 946-951. 10.1042/BST0350946

George, Christopher H., Thomas, Nia Lowri and Lai, Francis Anthony 2006. Role of ryanodine receptor mutations in cardiac pathology: more questions than answers? Biochemical Society Transactions 34 (5) , pp. 913-918. 10.1042/BST0340913

George, Christopher, Jundi, Hala, Walters, Nicola, Thomas, Nia Lowri, West, Robert Raynard and Lai, Francis Anthony 2005. Arrhythmogenic mutation-linked defects in ryanodine receptor autoregulation reveal a novel mechanism of Ca2+ release channel dysfunction. Circulation Research 98 (12) , pp. 88-97. 10.1161/01.RES.0000199296.70534.7c

Thomas, Nia Lowri 2005. Molecular mechanisms underlying cardiac ryanodine receptor dysfunction in sudden cardiac death. PhD Thesis, Cardiff University.
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George, Christopher H., Thomas, Nia Lowri and Lai, Francis Anthony 2005. Ryanodine receptor dysfunction in arrhythmia and sudden cardiac death. Future Cardiology 1 (4) , pp. 531-541. 10.2217/14796678.1.4.531

Thomas, Nia Lowri, Lai, Francis Anthony and George, Christopher H. 2005. Differential Ca2+ sensitivity of RyR2 mutations reveals distinct mechanisms of channel dysfunction in sudden cardiac death. Biochemical and Biophysical Research Communications 331 (1) , pp. 231-238. 10.1016/j.bbrc.2005.02.194

Thomas, Nia Lowri, George, Christopher and Lai, Francis Anthony 2004. Functional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death. Cardiovascular Research 64 (1) , pp. 52-60. 10.1016/j.cardiores.2004.06.009

George, Christopher, Jundi, Hala, Thomas, Nia Lowri, Scoote, Mark, Walters, Nicola, Williams, Alan John and Lai, Francis Anthony 2004. Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains. Molecular biology of the cell 15 (6) , pp. 2627-2638. 10.1091/mbc.E03-09-0688
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This list was generated on Mon Nov 18 05:13:35 2019 GMT.