Browse by Current Cardiff authors

Ipseiz, Natacha, Czubala, Magdalena A., Bart, Valentina M.T., Davies, Luke C., Jenkins, Robert H., Brennan, Paul and Taylor, Philip R. 2020. Effective in vivo gene modification in mouse tissue-resident peritoneal macrophages by intraperitoneal delivery of lentiviral vectors. Molecular Therapy - Methods and Clinical Development 16 , pp. 21-31. 10.1016/j.omtm.2019.10.004

Christopher, Edward, Poon, Michael T. C., Glancz, Laurence J., Hutchinson, Peter J., Kolias, Angelos G., Brennan, Paul M., Gray, William P. and British Neurosurgical Trainee Research Collaborative (BNTRC), 2019. Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma. Neurosurgical Review 42 (2) , pp. 427-431. 10.1007/s10143-018-0979-4

Brennan, Paul 2018. drawProteins: a Bioconductor/R package for reproducible and programmatic generation of protein schematics. F1000Research 7 , 1105. 10.12688/f1000research.14541.1

Brennan, Paul M., Kolias, Angelos G., Joannides, Alexis J., Shapey, Jonathan, Marcus, Hani J., Gregson, Barbara A., Grover, Patrick J., Hutchinson, Peter J., Coulter, Ian C., Afshari, F. T., Al Ahmed, S. Alli, Al-Mahfoudh, R., Bal, J., Belli, A., Borg, A., Bulters, D., Carleton-Bland, N., Chari, A., Coope, D., Cowie, C. J., Critchley, G., Dambatta, S., D'Aquino, D., Dhamija, B., Dobson, G., Fam, M. D., Glancz, L., Gray, William P., Halliday, J., Hamdan, A., Hill, C. S., Jamjoon, A. A. B., Jones, T. L., Joshi, S. M., Kailaya-Vasan, A., Karavasili, V., Khan, S., King, A., Kuenzel, A., Livermore, L., Lo, W., Martin, J., Matloob, S., Mitchell, P., Mowle, D., Narayanamurthy, H., Nelson, R., Ngoga, D., Noorani, I., O'Reilly, G., Othman, H., Owusu-Agyemang, K., Manjunath Prasad, K., Plaha, P., Pollock, J., Prasad, K. S., Price, R., Pringle, C., Ray, A., Reaper, J., Scotton, J., Simms, N., Smith, S., Statham, J., Steele, P., St George, J., Stovell, M., Tarnaris, A., Teo, M., Thomson, S., Thorne, L., Vintu, M., Whitfield, P., Wilson, M., Wilby, M., Woodfield, J. and Zaben, M. 2017. The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom. Journal of Neurosurgery 127 (4) , pp. 732-739. 10.3171/2016.8.JNS16134

Alsagaby, Suliman A., Brennan, Paul and Pepper, Christopher 2016. Key molecular drivers of chronic lymphocytic leukemia. Clinical Lymphoma, Myeloma and Leukemia 16 (11) , pp. 593-606. 10.1016/j.clml.2016.08.008

Welton, Joanne Louise, Brennan, Paul, Gurney, Mark, Webber, Jason Paul, Spary, Lisa Kate, Gil Carton, David, Falcón-Pérez, Juan Manuel, Walton, Sean Peter, Mason, Malcolm David, Tabi, Zsuzsanna and Clayton, Aled 2016. Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array. Journal of Extracellular Vesicles 5 , 31209. 10.3402/jev.v5.31209

Walsby, Elisabeth, Buggins, Andrea, Devereux, Stephen, Jones, Ceri, Pratt, Guy, Brennan, Paul, Fegan, Christopher and Pepper, Christopher 2014. Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia. Blood 123 (23) , pp. 3607-3617. 10.1182/blood-2013-12-544569

Coulter, Ian C., Kolias, Angelos G., Marcus, Hani J., Ahmed, Aminul I., Alli, Saira, Al-Mahfoudh, Rafid, Borg, Anouk, Cowie, Christopher J. A., Hill, Ciaran S., Joannides, Alexis J., Jones, Timothy L., Kailaya-Vasan, Ahilan, Livermore, James L., Narayanamurthy, Harsha, Ngoga, Desire, Shapey, Jonathan, Tarnaris, Andrew, Gregson, Barbara A., Gray, William Peter, Nelson, Richard J., Hutchinson, Peter J. and Brennan, Paul 2014. Proposal for a prospective multi-centre audit of chronic subdural haematoma management in the United Kingdom and Ireland. British Journal of Neurosurgery 28 (2) , pp. 199-203. 10.3109/02688697.2013.835378

Kolias, Angelos G., Coulter, Ian C., Marcus, Hani J., Gray, William Peter, Brennan, Paul and Hutchinson, Peter J. 2014. Chronic subdural haematoma: How can we improve patient care and outcomes? British Journal of Neurosurgery 28 (1) , pp. 136-137. 10.3109/02688697.2013.869555

Alsagaby, Suliman A., Khanna, Sanjay, Hart, Keith, Pratt, Guy, Fegan, Christopher, Pepper, Christopher, Brewis, Ian and Brennan, Paul 2014. Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia. Journal of Proteome Research 13 (11) , pp. 5051-5062. 10.1021/pr5002803

Wong, Ryan Francis, Pepper, Christopher John, Brennan, Paul, Nagorsen, Dirk, Man, Stephen Tzekwung and Fegan, Christopher Daniel 2013. Blinatumomab induces autologous T cell killing of chronic lymphocytic leukemia cells. Haematologica 98 (12) , pp. 1930-1938. 10.3324/haematol.2012.082248

Hoogendoorn, Bastiaan, Berube, Kelly Ann, Gregory, Clive James, Jones, Timothy Peter, Sexton, Keith John, Brennan, Paul, Brewis, Ian Andrew, Murison, Alexander James, Arthur, Robert Alan, Price, Heather Dawn, Morgan, Huw and Matthews, Ian Price 2012. Gene and protein responses of human lung tissue explants exposed to ambient particulate matter of different sizes. Inhalation Toxicology 24 (14) , pp. 966-975. 10.3109/08958378.2012.742600

Hamilton, Emma, Pearce, Laurence, Morgan, Liam, Robinson, Sophie, Ware, Victoria Lesley, Brennan, Paul, Thomas, N. Shaun B., Yallop, Deborah, Devereux, Stephen, Fegan, Christopher D., Buggins, Andrea G. S. and Pepper, Christopher John 2012. Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells. British Journal of Haematology 158 (5) , pp. 589-599. 10.1111/j.1365-2141.2012.09191.x

Masgras, I., Carrera, S., de Verdier, P. J., Brennan, Paul, Majid, A., Makhtar, W., Tulchinsky, E., Jones, G. D. D., Roninson, I. B. and Macip, S. 2012. Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21. Journal of Biological Chemistry 287 (13) , pp. 9845-9854. 10.1074/jbc.M111.250357

Pepper, Christopher John, Majid, Aneela, Lin, Thet Thet, Hewamana, Saman, Pratt, Guy, Walewska, Renata, Gesk, Stefan, Siebert, Reiner, Wagner, Simon, Kennedy, Ben, Miall, Fiona, Davis, Zadie A., Tracy, Ian, Gardiner, Anne C., Brennan, Paul, Hills, Robert Kerrin, Dyer, Martin J. S., Oscier, David and Fegan, Christopher Daniel 2012. Defining the prognosis of early stage chronic lymphocytic leukaemia patients. British Journal of Haematology 156 (4) , pp. 499-507. 10.1111/j.1365-2141.2011.08974.x

Watkins, Catherine Louise, Sayers, Edward John, Allender, Christopher John, Barrow, David Anthony, Fegan, Christopher Daniel, Brennan, Paul and Jones, Arwyn Tomos 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19 (12) , pp. 2124-2132. 10.1038/mt.2011.175

Sexton, Keith John, Balharry, Dominique Clare, Brennan, Paul, McLaren, James Edward, Brewis, Ian Andrew and Berube, Kelly Ann 2011. Proteomic profiling of human respiratory epithelia by iTRAQ reveals biomarkers of exposure and harm by tobacco smoke components. Biomarkers 16 (7) , pp. 567-576. 10.3109/1354750X.2011.608855

Pepper, Christopher John, Mahdi, J. G., Buggins, A. G. S., Hewamana, Saman, Walsby, Elisabeth Jane, Mahdi, Eamon, Al-Haza'a, A., Mahdi, Ali J., Lin, Thet Thet, Pearce, Laurence, Morgan, Liam David, Bowen, Ivor D., Brennan, Paul and Fegan, Christopher Daniel 2011. Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2. Cell Proliferation 44 (4) , pp. 380-390. 10.1111/j.1365-2184.2011.00760.x

Welton, Joanne L., Khanna, Sanjay, Giles, Peter James, Brennan, Paul, Brewis, Ian Andrew, Staffurth, John Nicholas, Mason, Malcolm David and Clayton, Aled 2010. Proteomics analysis of bladder cancer exosomes. Molecular & Cellular Proteomics 9 (6) , pp. 1324-1338. 10.1074/mcp.M000063-MCP201

Pearce, Laurence, Morgan, Liam David, Lin, Thet Thet, Hewamana, Saman, Matthews, Reginald James, Deaglio, Silvia, Rowntree, Clare, Fegan, Christopher Daniel, Pepper, Christopher John and Brennan, Paul 2010. Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38. Haematologica 95 (3) , pp. 514-517. 10.3324/haematol.2009.014381

Tediose, Teeo, Kolev, Martin Veselinov, Baalasubramanian, Sivasankar, Brennan, Paul, Morgan, Bryan Paul and Donev, Rossen Mintchev 2010. Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation. Nucleic Acids Research 38 (9) , pp. 2799-2812. 10.1093/nar/gkq013

Vaisitti, T., Aydin, S., Rossi, D., Cottino, F., Bergui, L., D'Arena, G., Bonello, L., Horenstein, A. L., Brennan, Paul, Pepper, Christopher John, Gaidano, G., Malavasi, F. and Deaglio, S. 2010. CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells. Leukemia 24 (5) , pp. 958-969. 10.1038/leu.2010.36

Alnagar, Fahima, Brennan, Paul and Brewis, Ian Andrew 2010. Bicarbonate-dependent serine/threonine protein dephosphorylation in capacitating boar spermatozoa. Journal of Andrology 31 (4) , pp. 393-405. 10.2164/jandrol.109.008383

Brewis, Ian and Brennan, Paul 2010. Proteomics technologies for the global identification and quantification of proteins. In: Donev, Rossen ed. Advances in Protein Chemistry and Structural Biology, Vol. 80. Elsevier, pp. 1-44. (10.1016/B978-0-12-381264-3.00001-1)

Watkins, Catherine Louise, Brennan, Paul, Fegan, Christopher Daniel, Takayama, Kentaro, Nakase, Ikuhiko, Futaki, Shiroh and Jones, Arwyn Tomos 2009. Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD. Journal of Controlled Release 140 (3) , pp. 237-244. 10.1016/j.jconrel.2009.04.028

Pepper, Christopher John, Hewamana, Saman, Brennan, Paul and Fegan, Christopher Daniel 2009. NF-κB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia. Future Oncology 5 (7) , pp. 1027-1037. 10.2217/fon.09.72

McLaren, James Edward, Zuo, Jianmin, Grimstead, Julia W., Poghosyan, Zaruhi, Bell, Andrew I., Rowe, Martin and Brennan, Paul 2009. STAT1 contributes to the maintenance of the latency III viral programme observed in Epstein-Barr virus-transformed B cells and their recognition by CD8+ T cells. Journal of General Virology 90 (9) , pp. 2239-2250. 10.1099/vir.0.011627-0

Brennan, Paul, Shore, Angharad M., Clement, Mathew, Hewamana, Saman, Jones, Catrin M., Giles, Peter James, Fegan, Christopher Daniel, Pepper, Christopher John and Brewis, Ian Andrew 2009. Quantitative nuclear proteomics reveals new phenotypes altered in lymphoblastoid cells. Proteomics - Clinical Applications 3 (3) , pp. 359-369. 10.1002/prca.200800137

Hewamana, Saman, Lin, Thet Thet, Rowntree, Clare, Karunanithi, Kamaraj, Pratt, Guy, Hills, Robert Kerrin, Fegan, Christopher Daniel, Brennan, Paul and Pepper, Christopher John 2009. Rel A is an independent biomarker of clinical outcome in chronic lymphocytic leukemia. Journal of Clinical Oncology 27 (5) , pp. 763-769. 10.1200/JCO.2008.19.1114

Raby, Anne-Catherine, Le Bouder, Emmanuel, Colmont, Chantal Sophie, Davies, James Anthony, Richards, Peter, Coles, Barbara, George, Christopher H., Jones, Simon Arnett, Brennan, Paul, Topley, Nicholas and Labeta, Mario Oscar 2009. Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering. The Journal of Immunology 183 (1) , pp. 506-517. 10.4049/jimmunol.0802909

Hewamana, Saman, Lin, Thet Thet, Jenkins, Chris, Burnett, Alan Kenneth, Jordan, Craig T., Fegan, Christopher Daniel, Brennan, Paul, Rowntree, Clare and Pepper, Christopher John 2008. The novel nuclear factor- B inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine. Clinical Cancer Research 14 (24) , pp. 8102-8111. 10.1158/1078-0432.CCR-08-1673

Pepper, Christopher John, Lin, Thet Thet, Pratt, Guy, Hewamana, Saman, Brennan, Paul, Hiller, Louise, Hills, Robert Kerrin, Ward, Rachel, Starczynski, Jane, Austen, Belinda, Hooper, Laura, Stankovic, Tatjana and Fegan, Christopher Daniel 2008. Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 112 (9) , pp. 3807-3817. 10.1182/blood-2008-05-157131

Hewamana, Saman, Alghazal, Suhair Alkailani, Lin, Thet Thet, Clement, Matthew, Jenkins, Christopher, Guzman, Monica L., Jordan, Craig T., Neelakantan, Sundar, Crooks, Peter A., Burnett, Alan Kenneth, Pratt, Guy, Fegan, Christopher Daniel, Rowntree, Clare, Brennan, Paul and Pepper, Christopher John 2008. The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target. Blood 111 (9) , pp. 4681-4689. 10.1182/blood-2007-11-125278

Chong, Lee Kien, Aicheler, Rebecca, Llewellyn-Lacey, Sian, Tomasec, Peter, Brennan, Paul and Wang, Edward Chung Yern 2008. Proliferation and interleukin 5 production by CD8hiCD57+ T cells. European Journal of Immunology 38 (4) , pp. 995-1000. 10.1002/eji.200737687

Brennan, Paul, Donev, Rossen Mintchev and Hewamana, Saman 2008. Targeting transcription factors for therapeutic benefit. Molecular Biosystems 4 (9) , pp. 909-919. 10.1039/b801920g

Brennan, Paul 2008. Duplication: most cases on database are innocent [Letter]. Nature 452 (7183) , p. 29. 10.1038/452029d

McLaren, James Edward, Rowe, Martin and Brennan, Paul 2007. Epstein-Barr virus induces a distinct form of DNA-bound STAT1 compared with that found in interferon-stimulated B lymphocytes. Journal of General Virology 88 (7) , pp. 1876-1886. 10.1099/vir.0.82741-0

Pepper, Christopher John, Ward, R., Lin, Thet Thet, Brennan, Paul, Starczynski, J., Musson, M., Rowntree, Claire, Bentley, P., Mills, K., Pratt, G. and Fegan, Christopher Daniel 2007. Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin. Leukemia 21 (4) , pp. 687-696. 10.1038/sj.leu.2404587

Shore, Angharad M., White, Paul Charles, Hui, Rosaline C.-Y., Essafi, Abdelkader, Lam, Eric W.-F., Rowe, Martin and Brennan, Paul 2006. Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A. Journal of Virology 80 (22) , pp. 11191-11199. 10.1128/JVI.00983-06

White, Paul Charles, Shore, A. M., Clement, Mathew, McLaren, James Edward, Soeiro, I., Lam, E. W.-F. and Brennan, Paul 2006. Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes. Oncogene 25 (15) , pp. 2170-2180. 10.1038/sj.onc.1209255

Omidvar, Nader, Wang, Edward Chung Yern, Brennan, Paul, Longhi, M. Paula, Smith, Richard A. G. and Morgan, Bryan Paul 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. Journal of immunology 176 (5) , pp. 2915-2923.

Omidvar, Nader, Wang, Edward Chung Yern, Brennan, Paul, Longhi, Maria P., Smith, Richard A. G. and Morgan, Bryan Paul 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. The Journal of Immunology 176 (5) , pp. 2915-2923. 10.4049/jimmunol.176.5.2915

Pepper, Christopher John, Brennan, Paul, Alghazal, S., Ward, R., Pratt, G., Starczynski, J., Lin, Thet Thet and Rowntree, C. 2006. CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38− counter-parts. Leukemia 20 (4) , pp. 743-744. 10.1038/sj.leu.2404133

Siebert, Stefan, Fielding, Ceri Alan, Williams, Bryan D. and Brennan, Paul 2005. Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF-kappaB activation due to decreased surface expression. FEBS Letters 579 (23) , pp. 5193-5198. 10.1016/j.febslet.2005.08.037

Siebert, Stefan, Fielding, Ceri Alan, Williams, Bryan D. and Brennan, Paul 2005. Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF-κB activation due to decreased surface expression. FEBS Letters 579 (23) , pp. 5193-5198. 10.1016/j.febslet.2005.08.037

Siebert, Stefa, Williams, Bryan D. and Brennan, Paul 2005. Reply [Letter]. Arthritis & Rheumatism 52 (9) , pp. 2952-2953. 10.1002/art.21369

Richardson, Ciaran Joseph, Brennan, Paul, Powell, Martin B., Prince, Stuart N., Chen, Yun-Hsiang, Spiller, O. Brad and Rowe, Martin 2005. Susceptibility of B lymphocytes to adenovirus type 5 infection is dependent upon both coxsackie-adenovirus receptor and αvβ5 integrin expression. Journal of General Virology 86 (6) , pp. 1669-1679. 10.1099/vir.0.80806-0

Siebert, Stefan, Amos, Nick, Fielding, Ceri Alan, Wang, Edward Chung Yern, Aksentijevich, Ivona, Williams, Bryan Davies and Brennan, Paul 2005. Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis & Rheumatism 52 (4) , pp. 1287-1282. 10.1002/art.20955

Breslin, Elaine M., White, Paul, Shore, Angharad M., Clement, Mathew and Brennan, Paul 2005. LY294002 and rapamycin co-operate to inhibit T-cell proliferation. British Journal of Pharmacology 144 (6) , pp. 791-800. 10.1038/sj.bjp.0706061

Sathish, Jean Gerard, Walters, Jenna, Luo, Jin Cai, Johnson, Kenneth G., LeRoy, Frances Gertrude, Brennan, Paul, Kim, Kwang P., Gygi, Steven P., Neel, Benjamin G. and Matthews, Reginald James 2004. CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells. Journal of Biological Chemistry 279 (46) , pp. 47783-47791. 10.1074/jbc.M402354200

Fielding, Ceri Alan, Siebert, Stefan, Rowe, Martin and Brennan, Paul 2004. Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression. FEBS Letters 570 (1-3) , pp. 138-142. 10.1016/j.febslet.2004.06.035

Moutaftsi, Magdalena, Brennan, Paul, Spector, Stephen A. and Tabi, Zsuzsanna 2004. Impaired lymphoid chemokine-mediated migration due to a block on the chemokine receptor switch in human cytomegalovirus-infected dendritic cells. Journal of Virology 78 (6) , pp. 3046-3054. 10.1128/JVI.78.6.3046-3054.2004

Burchill, M. A., Goetz, C. A., Prlic, M., O'Neil, J. J., Harmon, I. R., Bensinger, S. J., Turka, L. A., Brennan, Paul, Jameson, S. C. and Farrar, M. A. 2003. Distinct effects of STAT5 activation on CD4(+) and CD8(+) T cell homeostasis: Development of CD4(+)CD25(+) regulatory T cells versus CD8(+) memory T cells. The Journal of Immunology 171 (11) , pp. 5853-5864.

Richardson, Ciaran Joseph, Fielding, Ceri, Rowe, Martin and Brennan, Paul 2003. Epstein-Barr virus regulates STAT1 through latent membrane protein 1. Journal of Virology 77 (7) , pp. 4439-4443. 10.1128/JVI.77.7.4439-4443.2003

Ohtani, Naoko, Brennan, Paul, Gaubatz, Stefan, Sanij, Elaine, Hertzog, Paul, Wolvetang, Ernst, Ghysdael, Jacques, Rowe, Martin and Hara, Eiji 2003. Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5. Journal of cell biology 162 (2) , p. 173. 10.1083/jcb.200302085

Prince, S., Keating, S., Fielding, C., Brennan, Paul, Floettmann, E. and Rowe, Martin 2003. Latent membrane protein 1 inhibits Epstein-Barr virus lytic cycle induction and progress via different mechanisms. Journal of Virology 77 (8) , pp. 5000-5007. 10.1128/JVI.77.8.5000-5007.2003

Brennan, Paul, Mehl, Anja Maria, Jones, Matt and Rowe, Martin 2002. Phosphatidylinositol 3-kinase is essential for the proliferation of lymphoblastoid cells. Oncogene 21 (8) , pp. 1263-1271. 10.1038/sj.onc.1205182

Saitoh, Masao, Pullen, Nicholas, Brennan, Paul, Cantrell, Doreen, Dennis, Patrick B and Thomas, George 2002. Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site. Journal of Biological Chemistry 277 (22) , 20104-20112.. 10.1074/jbc.M201745200

Mehl, Anja Maria, Jones, Matthew, Rowe, Martin and Brennan, Paul 2001. Characterization of a CD40-dominant inhibitory receptor mutant. The Journal of Immunology 167 (11) , pp. 6388-6393.

Sathish, Jean Gerard, Johnson, Kenneth G., LeRoy, Frances Gertrude, Fuller, Kerenza J., Hallett, Maurice Bartlett, Brennan, Paul, Borysiewicz, Leszek, Sims, Martin J. and Matthews, Reginald James 2001. Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells. European Journal of Immunology 31 (12) , pp. 3649-3658. 10.1002/1521-4141(200112)31:12<3649::AID-IMMU3649>3.0.CO;2-8

Fielding, Ceri Alan, Sandvej, Kristian, Mehl, Anja Maria, Brennan, Paul, Jones, Matthew and Rowe, Martin 2001. Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways. Journal of Virology 75 (19) , pp. 9129-9141. 10.1128/JVI.75.19.9129-9141.2001

Brennan, Paul and Athie-Morales, Veronica 2001. Analysis of interleukin-2 signaling using affinity precipitations and polyacrylamide gel electrophoresis. In: O'Neill, Luke A. J. and Bowie, Andrew eds. Interleukin protocols, Vol. 60. Methods in Molecular Medicine, vol. 60. New Jersey: Humana Press, pp. 369-383. (10.1385/1-59259-146-9:369)

Brennan, Paul and Astoul, E. 2001. Applications of green fluorescent protein in cell signaling. In: O'Neill, Luke A. J. and Bowie, Andrew eds. Interleukin Protocols, Vol. 60. Methods in Molecular Medicine, vol. 60. Totowa, New Jersey: Humana Press, pp. 385-391. (10.1385/1-59259-146-9:385)

Brennan, Paul 2001. Signalling events regulating lymphoid growth and survival. Seminars in Cancer Biology 11 (6) , pp. 415-421. 10.1006/scbi.2001.0408

Mehl, Anja M., Floettmann, J. Eike, Jones, Matthew, Brennan, Paul and Rowe, Martin 2001. Characterization of intercellular adhesion molecule-1 regulation by Epstein-Barr virus-encoded latent membrane protein-1 identifies pathways that cooperate with nuclear factor κB to activate transcription. Journal of Biological Chemistry 276 (2) , pp. 984-992. 10.1074/jbc.M003758200

Brennan, Paul, Floettman, J. Eike, Mehl, Anja, Jones, Matthew and Rowe, Martin 2001. Mechanism of action of a novel latent membrane protein-1 dominant negative. Journal of Biological Chemistry 276 (2) , pp. 1195-1203. 10.1074/jbc.M005461200

Brennan, Paul, Babbage, J. W., Thomas, G. and Cantrell, D. 1999. p70s6k integrates phosphatidylinositol 3-Kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes. Molecular and Cellular Biology 19 (7) , pp. 4729-4738.

Vanhaesebroeck, Bart, Higashi, Kyochiro, Raven, Catherine, Welham, Melanie, Anderson, Simon, Brennan, Paul, Ward, Stephen G. and Waterfield, Michael D. 1999. Autophosphorylation of p110δ phosphoinositide 3‐kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo. The EMBO Journal 18 (5) , pp. 1292-1302. 10.1093/emboj/18.5.1292

Arrieumerlou, C., Donnadieu, E., Brennan, Paul, Keryer, G., Bismuth, G., Cantrell, D. and Trautmann, A. 1998. Involvement of phosphoinositide 3-kinase and Rac in membrane ruffling induced by IL-2 in T cells. European Journal of Immunology 28 (6) , pp. 1877-1885. 10.1002/(SICI)1521-4141(199806)28:06<1877::AID-IMMU1877>3.0.CO;2-I

Brennan, Paul and O'Neill, Luke A. J. 1998. Inhibition of nuclear factor kB by direct modification in whole cells mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers. Biochemical Pharmacology 55 (7) , pp. 965-973. 10.1016/S0006-2952(97)00535-2

Brennan, Paul, Babbage, Jane W., Burgering, Boudewijn M. T., Groner, Bernd, Reif, Karin and Cantrell, Doreen A. 1997. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity 7 (5) , pp. 679-689. 10.1016/S1074-7613(00)80388-X

Brennan, Paul and O'Neill, L. A. J. 1996. 2-Mercaptoethanol restores the ability of nuclear factor kB (NFkB) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Biochemical Journal -London- 320 , pp. 975-981.

Brennan, Paul and O'Neill, L. A. 1995. Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals. Acta Biochimica et Biophysica 1260 (2) , pp. 167-175. 10.1016/0167-4781(94)00186-7