ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Number of items: 38.
Hornsby, Amanda K.E., Buntwal, Luke, Carisi, Maria Carla, Santos, Vanessa V., Johnston, Fionnuala, Roberts, Luke D., Sassi, Martina, Mequinion, Mathieu, Stark, Romana, Reichenbach, Alex, Lockie, Sarah H., Siervo, Mario, Howell, Owain, Morgan, Alwena H., Wells, Timothy, Andrews, Zane B., Burn, David J. and Davies, Jeffrey S.
2020.
Unacylated-ghrelin impairs hippocampal neurogenesis and memory in mice and is altered in Parkinson's dementia in humans.
Cell Reports Medicine
1
(7)
, 100120.
10.1016/j.xcrm.2020.100120
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Tilston, Thomas W, Brown, Richard D, Wateridge, Matthew J, Arms-Williams, Bradley, Walker, Jamie J, Sun, Yuxiang and Wells, Timothy
2019.
A novel automated system yields reproducible temporal feeding patterns in laboratory rodents.
Journal of Nutrition
149
(9)
, pp. 1674-1684.
10.1093/jn/nxz116
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Braxton, Thomas M., Sarpong, Dionne Ea, Dovey, Janine L, Guillou, Anne, Evans, Ba, Castellano, Juan M., Keenan, Bethany E., Baraghithy, Saja, Evans, Sam L., Tena-Sempere, Manuel, Mollard, Patrice, Tam, Joseph and Wells, Timothy
2019.
Thermoneutrality improves skeletal impairment in adult Prader-Willi syndrome mice.
Journal of Endocrinology
243
(3)
, pp. 175-186.
10.1530/JOE-19-0279
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| Ratcliff, Michael, Rees, Daniel, McGrady, Scott, Buntwal, Luke, Hornsby, Amanda K. E., Bayliss, Jaqueline, Kent, Brianne A., Bussey, Timothy, Saksida, Lisa, Beynon, Amy L., Howell, Owain W., Morgan, Alwena H., Sun, Yuxiang, Andrews, Zane B., Wells, Timothy and Davies, Jeffrey S. 2019. Calorie restriction activates new adult born olfactory-bulb neurones in a ghrelin-dependent manner but acyl-ghrelin does not enhance subventricular zone neurogenesis. Journal of Neuroendocrinology 31 (7) , -. 10.1111/jne.12755 |
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| Welden, Justin R., Zhang, Zhaiyi, Duncan, Marilyn J., Falaleeva, Marina, Wells, Timothy and Stamm, Stefan 2018. The posterior pituitary expresses the serotonin receptor 2C. Neuroscience Letters 684 , pp. 132-139. 10.1016/j.neulet.2018.06.051 |
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Hopkins, Anna L., Nelson, Timothy A. S., Guschina, Irina A., Parsons, Lydia C., Lewis, Charlotte L., Brown, Richard C., Christian, Helen C., Davies, Jeffrey S. and Wells, Timothy
2017.
Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target-cell-induced acylation.
Scientific Reports
7
, 45541.
10.1038/srep45541
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Golding, David M., Rees, Daniel J., Davies, Jennifer R., Relkovic, Dinko, Furby, Hannah V., Guschina, Irina A., Hopkins, Anna L., Davies, Jeffrey S., Resnick, James L., Isles, Anthony R. and Wells, Timothy
2017.
Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome.
Journal of Endocrinology
232
(1)
, pp. 123-135.
10.1530/JOE-16-0367
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| Navein, Alice E., Cooke, Esther J., Davies, Jennifer R., Smith, Terence G., Wells, Lois H. M., Ohazama, Atsushi, Healy, Christopher, Sharpe, Paul T., Evans, Sam L., Evans, Bronwen A. J., Votruba, Marcela and Wells, Timothy 2016. Disrupted mitochondrial function in the Opa3L122P mouse model for Costeff Syndrome impairs skeletal integrity. Human Molecular Genetics 25 (12) , pp. 2404-2416. 10.1093/hmg/ddw107 |
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Hornsby, Amanda K. E., Redhead, Yushi T., Rees, Daniel J., Ratcliff, Michael S. G., Reichenbach, Alex, Wells, Timothy, Francis, Lewis, Amstalden, Katia, Andrews, Zane B. and Davies, Jeffrey S.
2016.
Short-term calorie restriction enhances adult hippocampal neurogenesis and remote fear memory in a Ghsr-dependent manner.
Psychoneuroendocrinology
63
, pp. 198-207.
10.1016/j.psyneuen.2015.09.023
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| Davies, Jennifer R., Humby, Trevor, Dwyer, Dominic M., Garfield, Alastair S., Furby, Hannah, Wilkinson, Lawrence Stephen, Wells, Timothy and Isles, Anthony Roger 2015. Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome. European Journal of Neuroscience 42 (4) , pp. 2105-2113. 10.1111/ejn.12972 |
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| Evans, Bronwen Alice James, James, T. W., James, K., Cox, A., Farr, L., Paisey, Stephen James, Dempster, D. W., Stone, M. D., Griffiths, P. A., Hugtenburg, R. P., Brady, Sir M. and Wells, Timothy 2014. Preclinical assessment of a new magnetic resonance-based technique for determining bone quality by characterization of trabecular microarchitecture. Calcified Tissue International 95 (6) , pp. 506-520. 10.1007/s00223-014-9922-z |
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| Man, Pui-Sin, Wells, Timothy and Carter, David Allan 2014. Cellular distribution of Egr1 transcription in the male rat pituitary gland. Journal of Molecular Endocrinology 53 (2) , pp. 271-280. 10.1530/JME-14-0158 |
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| El-Kasti, Muna Mustafa, Wells, Timothy and Carter, David Allan 2012. A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes. Human Molecular Genetics 21 (26) , pp. 5429-5442. 10.1093/hmg/dds389 |
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| Wells, Timothy, Davies, Jennifer Rhian, Guschina, Irina, Ball, Daniel, Davies, Jeffrey Stephens, Davies, Vanessa J., Evans, Bronwen Alice James and Votruba, Marcela 2012. Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome. Human Molecular Genetics 21 (22) , pp. 4836-4844. 10.1093/hmg/dds315 |
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| Glad, C., Kitchen, E., Russ, G., Harris, S., Davies, J., Gevers, E., Gabrielsson, B. and Wells, Timothy 2011. Reverse feeding suppresses the activity of the GH axis in rats and induces a preobesogenic state. Endocrinology 152 (3) , pp. 869-882. 10.1210/en.2010-0713 |
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| Evans, Bronwen Alice James, Bullen, Melanie Jean, Kench, Rebecca Carol, Fox, Rebecca E., Morgan, Liam David, Stevenson, Amy Elizabeth, Gevers, Evelien F., Perry, Mark J. and Wells, Timothy 2011. The influence of leptin on trabecular architecture and marrow adiposity in GH-deficient rats. Journal of Endocrinology 208 (1) , pp. 69-79. 10.1677/JOE-10-0178 |
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| Carter, David Allan, Rough, Kirsty and Wells, Timothy 2011. Transcription mapping of embryonic rat brain reveals EGR-1 induction in SOX2+ neural progenitor cells. Frontiers in Molecular Neuroscience 4 10.3389/fnmol.2011.00006 |
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| Davies, Jeffrey Stephens, Kotokorpi, Pia, Eccles, Sinan R., Barnes, Sarah K., Tokarczuk, Pawel Franciszek, Allen, Sophie Katharine, Whitworth, Hilary S., Guschina, Irina, Evans, Bronwen Alice James, Mode, Agneta, Zigman, Jeffrey M. and Wells, Timothy 2009. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Molecular Endocrinology 23 (6) , pp. 914-924. 10.1210/me.2008-0432 |
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| Stevenson, A. E., Evans, Bronwen Alice James, Gevers, E. F., Elford, Carole, McLeod, Robert William J., Perry, M. J., El-Kasti, M. M., Coschigano, K. T., Kopchick, J. J., Evans, Samuel Lewin and Wells, Timothy 2009. Does adiposity status influence femoral cortical strength in rodent models of growth hormone deficiency? American Journal of Physiology - Endocrinology and Metabolism 296 (1) , E147-E156. 10.1152/ajpendo.90689.2008 |
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| Wells, Timothy 2009. Ghrelin - Defender of fat. Progress in Lipid Research 48 (5) , pp. 257-274. 10.1016/j.plipres.2009.04.002 |
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| El-Kasti, Muna Mustafa, Christian, H. C., Huerta-Ocampo, I., Stolbrink, M., Gill, S., Houston, P. A., Davies, J. S., Chilcott, J., Hill, N., Matthews, D. R., Carter, David Allan and Wells, Timothy 2008. The pregnancy-induced increase in baseline circulating growth hormone in rats is not induced by ghrelin. Journal of Neuroendocrinology 20 (3) , pp. 309-322. 10.1111/j.1365-2826.2008.01650.x |
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| Davies, J. S., Kotokorpi, P., Lindahl, U., Oscarsson, J., Wells, Timothy and Mode, A. 2008. Effects of the synthetic liver X receptor agonist T0901317 on the growth hormone and thyroid hormone axes in male rats. Endocrine 33 (2) , pp. 196-204. 10.1007/s12020-008-9067-9 |
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| Mansergh, Fiona Catherine, Wells, Timothy, Elford, Carole, Evans, Samuel Lewin, Evans, Martin John, Perry, Mark J. and Evans, Bronwen Alice James 2007. Osteopenia in Sparc (osteonectin) deficient mice: characterization of phenotypic determinants of femoral strength and changes in gene expression. Physiological genomics 32 (1) , pp. 64-73. 10.1152/physiolgenomics.00151.2007 |
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| Man, Pui Sin, Wells, Timothy and Carter, David Allan 2007. Egr-1-d2EGFP transgenic rats identify transient populations of neurons and glial cells during postnatal brain development. Gene Expression Patterns 7 (8) , pp. 872-883. 10.1016/j.modgep.2007.06.006 |
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| Davies, Jeffrey Stephens, Gevers, Evelien F., Stevenson, Amy Elizabeth, Coschigano, Karen T., El-Kasti, Muna Mustafa, Bull, Melanie J., Elford, Carole., Evans, Bronwen Alice James, Kopchick, John J. and Wells, Timothy 2007. Adiposity profile in the dwarf (dw/dw) rat: an unusually lean model of profound growth hormone deficiency. American Journal of Physiology - Endocrinology and Metabolism 292 (5) , E1483-E1494. 10.1152/ajpendo.00417.2006 |
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| Holter, J. L., Davies, J. S., Man, P. S., Wells, Timothy and Carter, David Allan 2007. Transgenic delivery and detection of GFP in neuropeptide neurons. Neuropeptide Techniques, Neuromethods, vol. 39. Springer, pp. 31-44. (10.1007/978-1-60327-099-1_5) |
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| Humphries, Ann L., Wells, Timothy, Baler, Ruben, Klein, David C. and Carter, David Allan 2007. Rodent Aanat: intronic E-box sequences control tissue specificity but not rhythmic expression in the pineal gland. Molecular and Cellular Endocrinology 270 (1-2) , pp. 43-49. 10.1016/j.mce.2007.02.003 |
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| Davies, Jeffrey S., Thompson, N. M., Christian, H. C., Pinilla, L., Ebling, F. J. P., Tena-Sempere, M. and Wells, Timothy 2006. Hypothalamic expression of human growth hormone induces post-pubertal hypergonadotrophism in male transgenic growth retarded rats. Journal of Neuroendocrinology 18 (10) , pp. 719-731. 10.1111/j.1365-2826.2006.01467.x |
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| Martini, A. C., Fernández-Fernández, R., Tovar, S., Navarro, V. M., Vigo, E., Vazquez, Marisol, Davies, J. S., Thompson, N. M., Aguilar, E., Pinilla, L., Wells, Timothy, Dieguez, C and Tena-Sempere, M. 2006. Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats. Endocrinology 147 (5) , pp. 2374-2382. 10.1210/en.2005-1422 |
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| Davies, Jeffrey Stephens, Holter, J. L., Knight, D., Beaucourt, S. M., Murphy, D., Carter, David A. and Wells, Timothy 2004. Manipulating sorting signals to generate co-expression of somatostatin and eGFP in the regulated secretory pathway from a monocistronic construct. Journal of Molecular Endocrinology 33 (2) , pp. 523-532. 10.1677/jme.1.01578 |
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| Davies, Jeffrey S., Carter, David Allan and Wells, Timothy 2004. Photic stimulation inhibits growth hormone secretion in rats: A hypothalamic mechanism for transient entrainment. Endocrinology 145 (6) , 2950. 10.1210/en.2003-1236 |
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| Evans, Bronwen A. J., Warner, Justin T., Elford, Carole, Evans, Samuel Lewin, Laib, L., Bains, R. K., Gregory, John Welbourn and Wells, Tim 2003. Morphological determinants of femoral strength in growth hormone-deficient transgenic growth-retarded (Tgr) rats. Journal of Bone and Mineral Research 18 (7) , pp. 1308-1316. 10.1359/jbmr.2003.18.7.1308 |
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| Thompson, Nichola M., Davies, Jeffrey Stephens, Mode, Agneta, Houston, Pamela A. and Wells, Timothy 2003. Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats. Endocrinology 144 (11) , pp. 4859-4867. 10.1210/en.2003-0423 |
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| Slade, J. P., Man, Pui Sin, Wells, Timothy and Carter, David Allan 2002. Stimulus-specific induction of an Egr-I transgene in a rat brain. Neuroreport -Oxford- 13 (5) , pp. 671-674. |
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| Smith, Martyn, Burke, Zoe, Humphries, Ann, Wells, Timothy, Klein, David, Carter, David Allan and Baler, Ruben 2001. Tissue-specific transgenic knockdown of Fos-related antigen 2 (Fra-2) expression mediated by dominant negative Fra-2. Molecular and Cellular Biology 21 (11) , pp. 3704-3713. 10.1128/MCB.21.11.3704-3713.2001 |
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| Wells, Timothy and Carter, David Allan 2001. Genetic engineering of neural function in transgenic rodents: towards a comprehensive strategy? Journal of Neuroscience Methods 108 (2) , pp. 111-130. 10.1016/S0165-0270(01)00391-0 |
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| Wells, Timothy and Houston, P. A. 2001. Skeletal growth acceleration with growth hormone secretagogues in transgenic growth retarded rats: pattern-dependent effects and mechanisms of desensitization. Journal of Neuroendocrinology 13 (6) , pp. 496-504. 10.1046/j.1365-2826.2001.00661.x |
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| Warner, Justin T., Wells, Timothy, Elford, Carole, Evans, Bronwen Alice James, Evans, Samuel Lewin and Gregory, John Welbourn 2000. Undermineralisation and reduced bone strength in growth hormone (GH) deficient transgenic (Tgr) rats. Journal of Bone and Mineral Research (JBMR) 15 (6) , p. 1219. |
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