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Number of items: 35.

Menendez Gonzalez, Juan, Vukovic, Milica, Abdelfattah, Ali, Saleh, Lubaid, Almotiri, Alhomidi, Thomas, Leigh-Anne, Agirre-Lizaso, Alona, Azevedo, Aleksandra, Menezes, Ana Catarina, Tornillo, Giusy, Edkins, Sarah, Kong, Kay, Giles, Peter, Dos Anjos Afonso, Fernando, Tonks, Alex, Boyd, Ashleigh S, Kranc, Kamil R and Rodrigues, Neil P 2019. Gata2 as a crucial regulator of stem cells in hematopoiesis and acute myeloid leukemia. Stem Cell Reports 13 (2) , pp. 291-306. 10.1016/j.stemcr.2019.07.005
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Morgan, Rhys G, Ridsdale, Jenna, Payne, Megan, Heesom, Kate J, Wilson, Marieangela C, Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C, Blair, Allison, Waterman, Marian L, Tonks, Alex and Darley, Richard L 2019. LEF-1 drives aberrant B-catenin nuclear localization in myeloid leukemia cells. Haematologica 104 , pp. 1365-1377. 10.3324/haematol.2018.202846
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Hassan, Nurudeen, Ali, Ahmed, Withycombe, Cathryn, Ahluwalia, Maninder, Al-Nasseri, Raya Hamdan, Tonks, Alex and Morris, Keith 2018. TET-2 up-regulation is associated with the anti-inflammatory action of Vicenin-2. Cytokine 108 , pp. 37-42. 10.1016/j.cyto.2018.03.016
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Munje, C., Hills, Robert Kerrin, Whetton, A., Burnett, A., Darley, Richard Lawrence and Tonks, Alex 2015. Cord blood-derived quiescent CD34+ cells are more transcriptionally matched to AML blasts than cytokine-induced normal human hematopoietic CD34+ cells. Gene Expression 16 (4) , pp. 169-175. 10.3727/105221615X14399878166159
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Coles, Simon J., Gilmour, Marie N., Reid, R., Knapper, Steven, Burnett, A. K., Man, Stephen Tzekwung, Tonks, Alex and Darley, Richard Lawrence 2015. The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse. Leukemia 29 (9) , pp. 1952-1954. 10.1038/leu.2015.62

Morgan, Rhys G., Ridsdale, Jenna, Tonks, Alex and Darley, Richard Lawrence 2014. Factors affecting the nuclear localization of β-Catenin in normal and malignant tissue. Journal of Cellular Biochemistry 115 (8) , pp. 1351-1361. 10.1002/jcb.24803

Zabkiewicz, Joanna, Pearn, Lorna, Hills, Robert, Morgan, Rhys G., Tonks, Alex, Burnett, Alan K. and Darley, Richard 2014. The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. Haematologica 99 (5) , pp. 858-864. 10.3324/haematol.2013.096487

Hole, Paul Spencer, Zabkiewicz, Joanna, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul Charles, Marquez, Nuria, Hills, Robert Kerrin, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2013. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 122 (19) , pp. 3322-3330. 10.1182/blood-2013-04-491944

Morgan, Rhys G., Pearn, Lorna, Liddiard, Kate, Pumford, Sara Louise, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2013. γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia 27 (2) , pp. 336-343. 10.1038/leu.2012.221
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Daud, Siti Sarah, Pumford, Sara L, Gilmour, Marie N., Gilkes, Amanda F., Burnett, Alan Kenneth, Hills, Robert Kerrin, Tonks, Alex and Darley, Richard Lawrence 2012. Identification of the Wnt signalling protein, TCF7L2 as a significantly overexpressed transcription factor in AML [Abstract]. Blood 120 (21) , 1281.

Coles, Steven, Hills, Robert Kerrin, Wang, Edward Chung Yern, Burnett, Alan Kenneth, Man, Stephen Tzekwung, Darley, Richard Lawrence and Tonks, Alex 2012. Expression of CD200 on AML blasts directly suppresses memory T-cell function [Letter]. Leukemia 26 (9) , pp. 2148-2151. 10.1038/leu.2012.77
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Coles, Steven, Hills, Robert Kerrin, Wang, Edward Chung Yern, Burnett, Alan Kenneth, Man, Stephen Tzekwung, Darley, Richard Lawrence and Tonks, Alex 2012. Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells [Letter]. Leukemia 26 (9) , pp. 2146-2148. 10.1038/leu.2012.75
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Liddiard, Kate, Burnett, Alan Kenneth, Darley, Richard Lawrence and Tonks, Alex 2012. RUNX1-ETO deregulates the proliferation and growth factor responsiveness of human hematopoietic progenitor cells downstream of the myeloid transcription factor, MYCT1 [Letter]. Leukemia 26 (1) , pp. 177-179. 10.1038/leu.2011.188
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Coles, Steven, Man, Stephen Tzekwung, Hills, Robert Kerrin, Wang, Edward Chyng Yern, Burnett, Alan Kenneth, Darley, Richard Lawrence and Tonks, Alex 2011. CD200 inhibits memory Th1 cell function in acute myeloid leukaemia (AML)[Abstract]. Immunology 135 (S1) , p. 178. 10.1111/j.1365-2567.2011.03534.x

Coles, Steven, Wang, Edward Chung Yern, Man, Stephen Tzekwung, Hills, Robert Kerrin, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2011. CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia. Leukemia 25 (5) , pp. 792-799. 10.1038/leu.2011.1

Hole, Paul Spencer, Darley, Richard Lawrence and Tonks, Alex 2011. Do reactive oxygen species play a role in myeloid leukemias? Blood 117 (22) , pp. 5816-5826. 10.1182/blood-2011-01-326025

Zabkiewicz, Joanna, Pearn, Lorna, Hills, Robert Kerrin, Morgan, Rhys G., Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2010. PDK1 overexpression in acute myeloid leukemia; Clinical significance and potential as a therapeutic target [Abstract]. Blood 116 (21) , pp. 892-893.

Morgan, Rhys Gareth, Pearn, Lorna, Liddiard, Kate, Hills, Robert Kerrin, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2010. Distinct regulation of beta- and gamma-Catenin throughout hematopoietic development contrasts with their cooperative roles in acute myeloid leukemia [Abstract]. Blood 116 (21) , 1573.

Coles, Steven, Man, Stephen Tzekwung, Hills, Robert Kerrin, Wang, Edward Chung Yern, Burnett, Alan Kenneth, Darley, Richard Lawrence and Tonks, Alex 2010. Over-expression of CD200 un acute myeloid leukemia mediates the expansion of regulatory T-lymphocytes and directly inhibits natural killer cell tumor immunity [Abstract]. Blood 116 (21) , p. 218.

Liddiard, Kate, Hills, Robert Kerrin, Burnett, Alan Kenneth, Darley, Richard Lawrence and Tonks, Alex 2010. OGG1 is a novel prognostic indicator in acute myeloid leukaemia. Oncogene 29 (13) , pp. 2005-2012. 10.1038/onc.2009.462

Hole, Paul Spencer, Pearn, Lorna, Tonks, Amanda Jayne, James, Philip Eurig, Burnett, Alan Kenneth, Darley, Richard Lawrence and Tonks, Alex 2010. Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells. Blood 115 (6) , pp. 1238-1246. 10.1182/blood-2009-06-222869

Morris, R. H. K., Tonks, Amanda Jayne, Jones, K. P., Ahluwalia, M. K., Thomas, A. W., Tonks, Alex and Jackson, S. K. 2008. DPPC regulates COX-2 expression in monocytes via phosphorylation of CREB. Biochemical and Biophysical Research Communications 370 (1) , pp. 174-178. 10.1016/j.bbrc.2008.03.052

Tonks, Alex, Pearn, Lorna, Musson, Megan, Gilkes, Amanda F., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2007. Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia. Leukemia 21 (12) , pp. 2495-2505. 10.1038/sj.leu.2404961

Walsby, Elisabeth Jane, Gilkes, Amanda Frances, Tonks, Alex, Darley, Richard Lawrence and Mills, Kenneth Ian 2007. FUS expression alters the differentiation response to all-trans retinoic acid in NB4 and NB4R2 cells. British Journal of Haematology 139 (1) , pp. 94-97. 10.1111/j.1365-2141.2007.06756.x

Tonks, Amanda Jayne, Dudley, E., Porter, N. G., Parton, Joan, Brazier, J. S., Smith, E. L. and Tonks, Alex 2007. A 5.8KDa component of manuka honey stimulates immune cells via TLR4. Journal of Leukocyte Biology 82 (5) , pp. 1147-1155. 10.1189/jlb.1106683

Tonks, Alex, Hills, Robert Kerrin, White, Paul Charles, Rosie, B., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2007. CD200 as a prognostic factor in acute myeloid leukaemia. Leukemia 21 (3) , pp. 566-568. 10.1038/sj.leu.2404559

Tonks, Alex, Hills, Robert Kerrin, White, Paul Charles, Rosie, B., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2007. CD200 as a prognostic factor in acute myeloid leukaemia [Letter]. Leukemia 21 (3) , pp. 566-568. 10.1038/sj.leu.2404559

Tonks, Alex, Pearn, Lorna, Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2006. The sensitivity of human cells expressing RUNX1-RUNX1T1 to chemotherapeutic agents. Leukemia 20 (10) , pp. 1883-5. 10.1038/sj.leu.2404364

Tonks, Alex, Parton, Joan, Tonks, Amanda Jayne, Morris, Roger H. K., Finall, Alison, Jones, Kenneth P. and Jackson, Simon Karim 2005. Surfactant phospholipid DPPC downregulates monocyte respiratory burst via modulation of PKC. AJP Lung Cellular and Molecular Physiology 288 (6) , pp. 1070-80. 10.1152/ajplung.00386.2004

Tonks, Alex, Tonks, Amanda Jayne, Pearn, Lorna, Mohamad, Zulkhairi, Burnett, Alan Kenneth and Darley, Richard Lawrence 2005. Optimized retroviral transduction protocol which preserves the primitive subpopulation of human hematopoietic cells. Biotechnology Progress 21 (3) , pp. 953-958. 10.1021/bp0500314

Tonks, Alex, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, Laurence, Hoy, Terence George, Couzens, Stephen, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, L., Hoy, T., Couzens, Stephen, Fisher, J., Burnett, Alan Kenneth and Darley, Richard Lawrence 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence 2003. The AML-1 fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Tonks, Alex, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence 2003. The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Tonks, Amanda Jayne, Tonks, Alex, Morris, Roger H. K., Jones, Kenneth P. and Jackson, Simon Karim 2003. Regulation of platelet-activating factor synthesis in human monocytes by dipalmitoyl phosphatidylcholine. Journal of Leukocyte Biology 74 (1) , pp. 95-101. 10.1189/jlb.1202601

This list was generated on Mon Oct 21 05:11:18 2019 BST.