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Fielding, Ceri A., Jones, Gareth W., McLoughlin, Rachel M., McLeod, Louise, Hammond, Victoria J., Uceda, Javier, Williams, Anwen S., Lambie, Mark, Foster, Thomas L., Liao, Chia-Te, Rice, Christopher M., Greenhill, Claire J., Colmont, Chantal S., Hams, Emily, Coles, Barbara, Kift-Morgan, Ann, Newton, Zarabeth, Craig, Katherine J., Williams, John D., Williams, Geraint T., Davies, Simon J., Humphreys, Ian R., O'Donnell, Valerie B., Taylor, Philip R., Jenkins, Brendan J., Topley, Nicholas and Jones, Simon A.
2014.
Interleukin-6 signaling drives fibrosis in unresolved inflammation.
Immunity
40
(1)
, pp. 40-50.
10.1016/j.immuni.2013.10.022
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Raby, Anne-Catherine, Holst, Benjamin, Le Bouder, Emmanuel Jerome, Diaz, Constantinou, Ferran, Edgardo, Conraux, Laurence, Guillemot, Jean-Claude, Coles, Barbara, Kift-Morgan, Ann Patricia, Colmont, Chantal Sophie, Szakmany, Tamas, Ferrara, Pascual, Hall, Judith Elizabeth, Topley, Nicholas and Labeta, Mario Oscar 2013. Targeting the TLR co-receptor CD14 with TLR2-derived peptides modulates immune responses to pathogens. Science Translational Medicine 5 (185) , 185ra64. 10.1126/scitranslmed.3005544 |
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Raby, Anne-Catherine, Holst, Benjamin, Davies, James Anthony, Colmont, Chantal Sophie, Laumonnier, Yves, Coles, Barbara, Shah, Sanjoy, Hall, Judith Elizabeth, Topley, Nicholas, Köhl, Jörg, Morgan, Bryan Paul and Labeta, Mario Oscar 2011. TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. European Journal of Immunology 41 (9) , pp. 2741-2752. 10.1002/eji.201041350 |
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Clark, Stephen Robert, Guy, Christopher J., Scurr, Martin J., Taylor, Philip Russel, Kift-Morgan, Ann Patricia, Hammond, Victoria Jayne, Thomas, Christopher P., Coles, Barbara, Roberts, Gareth Wyn, Eberl, Matthias, Jones, Simon Arnett, Topley, Nicholas, Kotecha, Sailesh and O'Donnell, Valerie Bridget 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117 (6) , pp. 2033-2043. 10.1182/blood-2010-04-278887 |
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Coles, Barbara, Colmont, Chantal Sophie, Fielding, Ceri Alan, Kift-Morgan, Ann, Hams, Emily, Topley, Nicholas and Jones, Simon Arnett 2010. Local manipulation of IL-6 trans-signaling therapeutically enhances anti-microbial host defense [Abstract]. Cytokine 52 (1-2) , pp. 80-81. 10.1016/j.cyto.2010.07.335 |
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Maskrey, B. H., Bermudez-Fajardo, A., Morgan, Alwena Haf, Stewart-Jones, Esther, Dioszeghy, Vincent, Taylor, G. W., Baker, P. R. S., Coles, Barbara, Coffey, Marcus Jonathan, Kuhn, H. and O'Donnell, Valerie Bridget 2009. Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase [Addition]. Journal of Biological Chemistry 284 (37) , p. 25460. 10.1074/jbc.A611776200 |
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Raby, Anne-Catherine, Le Bouder, Emmanuel, Colmont, Chantal Sophie, Davies, James Anthony, Richards, Peter, Coles, Barbara, George, Christopher H., Jones, Simon Arnett, Brennan, Paul, Topley, Nicholas and Labeta, Mario Oscar 2009. Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering. The Journal of Immunology 183 (1) , pp. 506-517. 10.4049/jimmunol.0802909 |
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Morgan, Alwena Haf, Dioszeghy, Vincent, Maskrey, Benjamin, Thomas, Christopher P., Clark, Stephen Robert, Mathie, Sara A., Lloyd, Clare M., Kuhn, Hartmut, Topley, Nicholas, Coles, Barbara, Taylor, Philip Russel, Jones, Simon Arnett and O'Donnell, Valerie Bridget 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284 (32) , pp. 21185-21191. 10.1074/jbc.M109.021634 |
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Morton, Jonathan, Coles, Barbara, Wright, Kate Louise, Gallimore, Awen Myfanwy, Morrow, Jason D., Terry, Erin S., Anning, Peter, Morgan, Bryan Paul, Dioszeghy, Vincent, Kuhn, Hartmut, Chaitidis, Pavlos, Hobbs, Adrian J., Jones, Simon Arnett and O'Donnell, Valerie Bridget 2008. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN -dependent iNOS expression in the vasculature of healthy mice. Blood 111 (10) , pp. 5187-5194. 10.1182/blood-2007-10-117283 |
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Coles, Barbara, Wilton, L. A. K., Good, Mark Andrew, Chapman, P. F. and Wann, Kenneth Taylor 2008. Potassium channels in hippocampal neurones are absent in a transgenic but not in a chemical model of Alzheimer's disease. Brain Research 1190 , pp. 1-14. 10.1016/j.brainres.2007.10.071 |
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Coles, Barbara, Fielding, Ceri Alan, Rose-John, Stefan, Scheller, J., Jones, S. A. and O'Donnell, Valerie Bridget 2007. Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo. American Journal of Pathology 171 (1) , pp. 315-325. 10.2353/ajpath.2007.061078 |
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Anning, Peter Brian, Coles, Barbara, Morton, Jonathan, Wang, Haibin, Uddin, Jashim, Morrow, Jason D., Dey, Sudhansu K., Marnett, Lawrence J. and O'Donnell, Valerie Bridget 2006. Nitric Oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. Blood 108 (13) , pp. 4059-4062. 10.1182/blood-2006-02-005330 |
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Williams, Paula Claire, Coffey, Marcus Jonathan, Coles, Barbara, Sanchez, Stephanie, Morrow, Jason D., Cockcroft, John Ronald, Lewis, Malcolm John and O'Donnell, Valerie Bridget 2005. In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. Blood 106 (8) , pp. 2737-2743. 10.1182/blood-2005-02-0664 |
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Coffey, Marcus Jonathan, Coles, Barbara, Locke, Matthew, Bermudez-Fajardo, Alexandra, Williams, Paula Claire, Jarvis, Gavin E. and O'Donnell, Valerie Bridget 2004. Interactions of 12-lipoxygenase with phospholipase A2 isoforms following platelet activation through the glycoprotein VI collagen receptor. FEBS Letters 576 (1-2) , pp. 165-168. 10.1016/j.febslet.2004.09.007 |
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Coffey, Marcus Jonathan, Jarvis, Gavin E, Gibbins, Jonathan M., Coles, Barbara, Barrett, Natasha E., Wylie, Oliver R.E. and O'Donnell, Valerie Bridget 2004. Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. Circulation Research 94 (12) , pp. 1598-1605. 10.1161/01.RES.0000132281.78948.65 |
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Coles, Barbara, Bloodsworth, Allison, Clark, Stephen Robert, Lewis, Malcolm John, Cross, Andrew R., Freeman, Bruce A. and O'Donnell, Valerie Bridget 2002. Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells. Circulation Research 91 (5) , pp. 375-381. 10.1161/01.RES.0000032114.68919.EF |
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Coffey, Marcus Jonathan, Natarajan, Rama, Chumley, Philip H., Coles, Barbara, Thimmalapura, Pushpa-Rekha, Nowell, Mari Ann, Kühn, Hartmut, Lewis, Malcolm John, Freeman, Bruce A. and O'Donnell, Valerie Bridget 2001. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 98 (14) , pp. 8006-8011. 10.1073/pnas.141136098 |
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