Browse by Current Cardiff authors

Leonenko, Ganna, Shoai, Maryam, Bellou, Eftychia, Sims, Rebecca, Williams, Julie, Hardy, John and Escott-Price, Valentina 2019. Genetic risk for Alzheimer's disease is distinct from genetic risk for amyloid deposition. Annals of Neurology 86 (3) , pp. 427-435. 10.1002/ana.25530

Baker, Emily, Sims, Rebecca, Leonenko, Ganna, Frizzati, Aura, Harwood, Janet, Grozena, Detelina, Morgan, Kevin, Passmore, Peter, Holmes, Clives, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Bossu, Paola, Spalletta, Gianfranco, Goate, Alison, Crunchaga, Carlos, Maier, Wolfgang, Heun, Reinhard, Jessen, Frank, Peters, Oliver, Dichgans, Martin, Frolich, Lutz, Ramirez, Alfredo, Jones, Lesley, Hardy, John, Ivanov, Dobril, Hill, Matthew, Holmans, Peter, Allen, Nicholas, Morgan, Paul, Seshadri, Sudha, Schellenberg, Gerard, Amouvel, Philippe, Williams, Julie and Escott-Price, Valentina 2019. Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease. PLoS ONE 14 (7) , e0218111. 10.1371/journal.pone.0218111

Lancaster, Thomas M., Hill, Matthew J., Sims, Rebecca and Williams, Julie 2019. Microglia - mediated immunity partly contributes to the genetic association between Alzheimer's disease and hippocampal volume. Brain, Behavior, and Immunity 79 , pp. 267-273. 10.1016/j.bbi.2019.02.011

Leonenko, Ganna, Sims, Rebecca, Shoai, Maryam, Frizzati, Aura, Bossu, Paola, Spalletta, Gianfranco, Fox, Nick C, Williams, Julie, Hardy, John and Escott-Price, Valentina 2019. Polygenic risk and hazard scores for Alzheimer's disease prediction. Annals of Clinical and Translational Neurology 6 (3) , pp. 456-465. 10.1002/acn3.716

Kunkle, Brian W., Grenier-Boley, Benjamin, Sims, Rebecca, Bis, Joshua C., Damotte, Vincent, Naj, Adam C., Boland, Anne, Vronskaya, Maria, van der Lee, Sven J., Amlie-Wolf, Alexandre, Bellenguez, Céline, Frizatti, Aura, Chouraki, Vincent, Martin, Eden R., Sleegers, Kristel, Badarinarayan, Nandini, Jakobsdottir, Johanna, Hamilton-Nelson, Kara L., Moreno-Grau, Sonia, Olaso, Robert, Raybould, Rachel, Chen, Yuning, Kuzma, Amanda B., Hiltunen, Mikko, Morgan, Taniesha, Ahmad, Shahzad, Vardarajan, Badri N., Epelbaum, Jacques, Hoffmann, Per, Boada, Merce, Beecham, Gary W., Garnier, Jean-Guillaume, Harold, Denise, Fitzpatrick, Annette L., Valladares, Otto, Moutet, Marie-Laure, Gerrish, Amy, Smith, Albert V., Qu, Liming, Bacq, Delphine, Denning, Nicola, Jian, Xueqiu, Zhao, Yi, Del Zompo, Maria, Fox, Nick C., Choi, Seung-Hoan, Mateo, Ignacio, Hughes, Joseph T., Adams, Hieab H., Malamon, John, Sanchez-Garcia, Florentino, Patel, Yogen, Brody, Jennifer A., Dombroski, Beth A., Naranjo, Maria Candida Deniz, Daniilidou, Makrina, Eiriksdottir, Gudny, Mukherjee, Shubhabrata, Wallon, David, Uphill, James, Aspelund, Thor, Cantwell, Laura B., Garzia, Fabienne, Galimberti, Daniela, Hofer, Edith, Butkiewicz, Mariusz, Fin, Bertrand, Scarpini, Elio, Sarnowski, Chloe, Bush, Will S., Meslage, Stéphane, Kornhuber, Johannes, White, Charles C., Song, Yuenjoo, Barber, Robert C., Engelborghs, Sebastiaan, Sordon, Sabrina, Voijnovic, Dina, Adams, Perrie M., Vandenberghe, Rik, Mayhaus, Manuel, Cupples, L. Adrienne, Albert, Marilyn S., De Deyn, Peter P., Gu, Wei, Himali, Jayanadra J., Beekly, Duane, Squassina, Alessio, Hartmann, Annette M., Orellana, Adelina, Blacker, Deborah, Rodriguez-Rodriguez, Eloy, Lovestone, Simon, Garcia, Melissa E., Doody, Rachelle S., Munoz-Fernadez, Carmen, Sussams, Rebecca, Lin, Honghuang, Fairchild, Thomas J., Benito, Yolanda A., Holmes, Clive, Karamuji-omi, Hata, Frosch, Matthew P., Thonberg, Hakan, Maier, Wolfgang, Roschupkin, Gena, Ghetti, Bernardino, Giedraitis, Vilmantas, Kawalia, Amit, Li, Shuo, Huebinger, Ryan M., Kilander, Lena, Moebus, Susanne, Hernández, Isabel, Kamboh, M. Ilyas, Brundin, RoseMarie, Turton, James, Yang, Qiong, Katz, Mindy J., Concari, Letizia, Lord, Jenny, Beiser, Alexa S., Keene, C. Dirk, Helisalmi, Seppo, Kloszewska, Iwona, Kukull, Walter A., Koivisto, Anne Maria, Lynch, Aoibhinn, Tarraga, Lluís, Larson, Eric B., Haapasalo, Annakaisa, Lawlor, Brian, Mosley, Thomas H., Lipton, Richard B., Solfrizzi, Vincenzo, Gill, Michael, Longstreth, W. T., Montine, Thomas J., Frisardi, Vincenza, Diez-Fairen, Monica, Rivadeneira, Fernando, Petersen, Ronald C., Deramecourt, Vincent, Alvarez, Ignacio, Salani, Francesca, Ciaramella, Antonio, Boerwinkle, Eric, Reiman, Eric M., Fievet, Nathalie, Rotter, Jerome I., Reisch, Joan S., Hanon, Olivier, Cupidi, Chiara, Andre Uitterlinden, A. G., Royall, Donald R., Dufouil, Carole, Maletta, Raffaele Giovanni, de Rojas, Itziar, Sano, Mary, Brice, Alexis, Cecchetti, Roberta, George-Hyslop, Peter St, Ritchie, Karen, Tsolaki, Magda, Tsuang, Debby W., Dubois, Bruno, Craig, David, Wu, Chuang-Kuo, Soininen, Hilkka, Avramidou, Despoina, Albin, Roger L., Fratiglioni, Laura, Germanou, Antonia, Apostolova, Liana G., Keller, Lina, Koutroumani, Maria, Arnold, Steven E., Panza, Francesco, Gkatzima, Olymbia, Asthana, Sanjay, Hannequin, Didier, Whitehead, Patrice, Atwood, Craig S., Caffarra, Paolo, Hampel, Harald, Quintela, Inés, Carracedo, Ángel, Lannfelt, Lars, Rubinsztein, David C., Barnes, Lisa L., Pasquier, Florence, Frölich, Lutz, Barral, Sandra, McGuinness, Bernadette, Beach, Thomas G., Johnston, Janet A., Becker, James T., Passmore, Peter, Bigio, Eileen H., Schott, Jonathan M., Bird, Thomas D., Warren, Jason D., Boeve, Bradley F., Lupton, Michelle K., Bowen, James D., Proitsi, Petra, Boxer, Adam, Powell, John F., Burke, James R., Kauwe, John S. K., Burns, Jeffrey M., Mancuso, Michelangelo, Buxbaum, Joseph D., Bonuccelli, Ubaldo, Cairns, Nigel J., McQuillin, Andrew, Cao, Chuanhai, Livingston, Gill, Carlson, Chris S., Bass, Nicholas J., Carlsson, Cynthia M., Hardy, John, Carney, Regina M., Bras, Jose, Carrasquillo, Minerva M., Guerreiro, Rita, Allen, Mariet, Chui, Helena C., Fisher, Elizabeth, Masullo, Carlo, Crocco, Elizabeth A., DeCarli, Charles, Bisceglio, Gina, Dick, Malcolm, Ma, Li, Duara, Ranjan, Graff-Radford, Neill R., Evans, Denis A., Hodges, Angela, Faber, Kelley M., Scherer, Martin, Fallon, Kenneth B., Riemenschneider, Matthias, Fardo, David W., Heun, Reinhard, Farlow, Martin R., Kölsch, Heike, Ferris, Steven, Leber, Markus, Foroud, Tatiana M., Heuser, Isabella, Galasko, Douglas R., Giegling, Ina, Gearing, Marla, Hüll, Michael, Geschwind, Daniel H., Gilbert, John R., Morris, John, Green, Robert C., Mayo, Kevin, Growdon, John H., Feulner, Thomas, Hamilton, Ronald L., Harrell, Lindy E., Drichel, Dmitriy, Honig, Lawrence S., Cushion, Thomas D., Huentelman, Matthew J., Hollingworth, Paul, Hulette, Christine M., Hyman, Bradley T., Marshall, Rachel, Jarvik, Gail P., Meggy, Alun, Abner, Erin, Menzies, Georgina E., Jin, Lee-Way, Leonenko, Ganna, Real, Luis M., Jun, Gyungah R., Baldwin, Clinton T., Grozeva, Detelina, Karydas, Anna, Russo, Giancarlo, Kaye, Jeffrey A., Kim, Ronald, Jessen, Frank, Kowall, Neil W., Vellas, Bruno, Kramer, Joel H., Vardy, Emma, LaFerla, Frank M., Jöckel, Karl-Heinz, Lah, James J., Dichgans, Martin, Leverenz, James B., Mann, David, Levey, Allan I., Pickering-Brown, Stuart, Lieberman, Andrew P., Klopp, Norman, Lunetta, Kathryn L., Wichmann, H-Erich, Lyketsos, Constantine G., Morgan, Kevin, Marson, Daniel C., Brown, Kristelle, Martiniuk, Frank, Medway, Christopher, Mash, Deborah C., Nöthen, Markus M., Masliah, Eliezer, Hooper, Nigel M., McCormick, Wayne C., Daniele, Antonio, McCurry, Susan M., Bayer, Antony, McDavid, Andrew N., Gallacher, John, McKee, Ann C., van den Bussche, Hendrik, Mesulam, Marsel, Brayne, Carol, Miller, Bruce L., Riedel-Heller, Steffi, Miller, Carol A., Miller, Joshua W., Al-Chalabi, Ammar, Morris, John C., Shaw, Christopher E., Myers, Amanda J., Wiltfang, Jens, O'Bryant, Sid, Olichney, John M., Alvarez, Victoria, Parisi, Joseph E., Singleton, Andrew B., Paulson, Henry L., Collinge, John, Perry, William R., Mead, Simon, Peskind, Elaine, Cribbs, David H., Rossor, Martin, Pierce, Aimee, Ryan, Natalie S., Poon, Wayne W., Nacmias, Benedetta, Potter, Huntington, Sorbi, Sandro, Quinn, Joseph F., Sacchinelli, Eleonora, Raj, Ashok, Spalletta, Gianfranco, Raskind, Murray, Caltagirone, Carlo, Bossù, Paola, Orfei, Maria Donata, Reisberg, Barry, Clarke, Robert, Reitz, Christiane, Smith, A David, Ringman, John M., Warden, Donald, Roberson, Erik D., Wilcock, Gordon, Rogaeva, Ekaterina, Bruni, Amalia Cecilia, Rosen, Howard J., Gallo, Maura, Rosenberg, Roger N., Ben-Shlomo, Yoav, Sager, Mark A., Mecocci, Patrizia, Saykin, Andrew J., Pastor, Pau, Cuccaro, Michael L., Vance, Jeffery M., Schneider, Julie A., Schneider, Lori S., Slifer, Susan, Seeley, William W., Smith, Amanda G., Sonnen, Joshua A., Spina, Salvatore, Stern, Robert A., Swerdlow, Russell H., Tang, Mitchell, Tanzi, Rudolph E., Trojanowski, John Q., Troncoso, Juan C., Van Deerlin, Vivianna M., Van Eldik, Linda J., Vinters, Harry V., Vonsattel, Jean Paul, Weintraub, Sandra, Welsh-Bohmer, Kathleen A., Wilhelmsen, Kirk C., Williamson, Jennifer, Wingo, Thomas S., Woltjer, Randall L., Wright, Clinton B., Yu, Chang-En, Yu, Lei, Saba, Yasaman, Pilotto, Alberto, Bullido, Maria J., Peters, Oliver, Crane, Paul K., Bennett, David, Bosco, Paola, Coto, Eliecer, Boccardi, Virginia, De Jager, Phil L., Lleo, Alberto, Warner, Nick, Lopez, Oscar L., Ingelsson, Martin, Deloukas, Panagiotis, Cruchaga, Carlos, Graff, Caroline, Gwilliam, Rhian, Fornage, Myriam, Goate, Alison M., Sanchez-Juan, Pascual, Kehoe, Patrick G., Amin, Najaf, Ertekin-Taner, Nilifur, Berr, Claudine, Debette, Stéphanie, Love, Seth, Launer, Lenore J., Younkin, Steven G., Dartigues, Jean-Francois, Corcoran, Chris, Ikram, M. Arfan, Dickson, Dennis W., Nicolas, Gael, Campion, Dominique, Tschanz, JoAnn, Schmidt, Helena, Hakonarson, Hakon, Clarimon, Jordi, Munger, Ron, Schmidt, Reinhold, Farrer, Lindsay A., Van Broeckhoven, Christine, O'Donovan, Michael C, DeStefano, Anita L., Jones, Lesley, Haines, Jonathan L., Deleuze, Jean-Francois, Owen, Michael J, Gudnason, Vilmundur, Mayeux, Richard, Escott-Price, Valentina, Psaty, Bruce M., Ramirez, Alfredo, Wang, Li-San, Ruiz, Agustin, van Duijn, Cornelia M., Holmans, Peter, Seshadri, Sudha, Williams, Julie, Amouyel, Phillippe, Schellenberg, Gerard D., Lambert, Jean-Charles and Pericak-Vance, Margaret A. 2019. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics 51 (3) , pp. 414-430. 10.1038/s41588-019-0358-2

Hodgetts, Carl, Shine, Jonathan, Williams, Huw, Postans, Mark, Sims, Rebecca, WIlliams, Julie, Lawrence, Andrew and Graham, Kim 2019. Increased posterior default mode network activity and structural connectivity in young adult APOE-ε4 carriers: a multi-modal imaging investigation. Neurobiology of Aging 73 , pp. 82-91. 10.1016/j.neurobiolaging.2018.08.026

Gusareva, Elena S., Twizere, Jean-Claude, Sleegers, Kristel, Dourlen, Pierre, Abisambra, Jose F., Meier, Shelby, Cloyd, Ryan, Weiss, Blaine, Dermaut, Bart, Bessonov, Kyrylo, van der Lee, Sven J., Carrasquillo, Minerva M., Katsumata, Yuriko, Cherkaoui, Majid, Asselbergh, Bob, Ikram, M. Arfan, Mayeux, Richard, Farrer, Lindsay A., Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Sims, Rebecca, Williams, Julie, Amouyel, Philippe, van Duijn, Cornelia M., Ertekin-Taner, Nilüfer, Van Broeckhoven, Christine, Dequiedt, Franck, Fardo, David W., Lambert, Jean-Charles and Van Steen, Kristel 2018. Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. Neurobiology of Aging 72 , e3-e12. 10.1016/j.neurobiolaging.2018.08.001

Koriath, C., Kenny, J., Adamson, G., Druyeh, R., Taylor, W., Beck, J., Quinn, L., Mok, T. H., Dimitriadis, A., Norsworthy, P., Bass, N., Carter, J., Walker, Z., Kipps, C., Coulthard, E., Polke, J. M., Bernal-Quiros, M., Denning, N., Thomas, R., Raybould, R., Williams, J., Mummery, C. J., Wild, E. J., Houlden, H., Tabrizi, S. J., Rossor, M. N., Hummerich, H., Warren, J. D., Rowe, J. B., Rohrer, J. D., Schott, J. M., Fox, N. C., Collinge, J. and Mead, S. 2018. Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series. Molecular Psychiatry 10.1038/s41380-018-0224-0

Ahmad, Shahzad, Bannister, Christian, van der Lee, Sven J., Vojinovic, Dina, Adams, Hieab H.H., Ramirez, Alfredo, Escott-Price, Valentina, Sims, Rebecca, Baker, Emily, Williams, Julie, Holmans, Peter, Vernooij, Meike W., Ikram, M. Arfan, Amin, Najaf and van Duijn, Cornelia M. 2018. Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study. Alzheimer's and Dementia 14 (7) , pp. 848-857. 10.1016/j.jalz.2018.01.005

Baker, Emily, Schmidt, Karl Michael, Sims, Rebecca, O'Donovan, Michael C., Williams, Julie, Holmans, Peter and Escott-Price, Valentina 2018. POLARIS: polygenic LD-adjusted risk score approach for set-based analysis of GWAS data. Genetic Epidemiology 42 (4) , pp. 366-377. 10.1002/gepi.22117

Sims, Rebecca, van der Lee, Sven J, Naj, Adam C, Badarinarayan, Nandini, Morgan, Taniesha, Denning, Nicola, Majounie, Elisa, O'Donovan, Michael, Owen, Michael, Jones, Lesley, Escott-Price, Valentina, Holmans, Peter and Williams, Julie 2017. Rare coding variants in PLCG2, ABI3 and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics 49 , pp. 1373-1384. 10.1038/ng.3916

Blauwendraat, Cornelis, Faghri, Faraz, Pihlstrom, Lasse, Geiger, Joshua T., Elbaz, Alexis, Lesage, Suzanne, Corvol, Jean-Christophe, May, Patrick, Nicolas, Aude, Abramzon, Yevgeniya, Murphy, Natalie A., Gibbs, J. Raphael, Ryten, Mina, Ferrari, Raffaele, Bras, Jose, Guerreiro, Rita, Williams, Julie, Sims, Rebecca, Lubbe, Steven, Hernandez, Dena G., Mok, Kin Y., Robak, Laurie, Campbell, Roy H., Rogaeva, Ekaterina, Traynor, Bryan J., Chia, Ruth, Chung, Sun Ju, Hardy, John A., Brice, Alexis, Wood, Nicholas W., Houlden, Henry, Shulman, Joshua M., Morris, Huw R., Gasser, Thomas, Krüger, Rejko, Heutink, Peter, Sharma, Manu, Simón-Sánchez, Javier, Nalls, Mike A., Singleton, Andrew B. and Scholz, Sonja W. 2017. NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases. Neurobiology of Aging 57 , p. 247. 10.1016/j.neurobiolaging.2017.05.009

Huang, Kuan-lin, Marcora, Edoardo, Pimenova, Anna A, Di Narzo, Antonio F, Kapoor, Manav, Jin, Sheng Chih, Harari, Oscar, Bertelsen, Sarah, Fairfax, Benjamin P, Czajkowski, Jake, Chouraki, Vincent, Grenier-Boley, Benjamin, Bellenguez, Céline, Deming, Yuetiva, McKenzie, Andrew, Raj, Towfique, Renton, Alan E, Budde, John, Smith, Albert, Fitzpatrick, Annette, Bis, Joshua C, DeStefano, Anita, Adams, Hieab H H, Ikram, M Arfan, van der Lee, Sven, Del-Aguila, Jorge L, Fernandez, Maria Victoria, Ibañez, Laura, Sims, Rebecca, Escott-Price, Valentina, Mayeux, Richard, Haines, Jonathan L, Farrer, Lindsay A, Pericak-Vance, Margaret A, Lambert, Jean Charles, van Duijn, Cornelia, Launer, Lenore, Seshadri, Sudha, Williams, Julie, Amouyel, Philippe, Schellenberg, Gerard D, Zhang, Bin, Borecki, Ingrid, Kauwe, John S K, Cruchaga, Carlos, Hao, Ke and Goate, Alison M 2017. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease. Nature Neuroscience 20 (8) , pp. 1052-1061. 10.1038/nn.4587

DeMichele-Sweet, M A A, Weamer, E A, Klei, L, Vrana, D T, Hollingshead, D J, Seltman, H J, Sims, Rebecca, Foroud, T, Hernandez, I, Moreno-Grau, S, Tárraga, L, Boada, M, Ruiz, A, Williams, Julie, Mayeux, R, Lopez, O L, Sibille, E L, Kamboh, M I, Devlin, B and Sweet, R A 2017. Genetic risk for schizophrenia and psychosis in Alzheimer disease. Molecular Psychiatry 23 , pp. 963-972. 10.1038/mp.2017.81

Foley, Sonya, Tansey, Katherine E., Caseras, Xavier, Lancaster, Thomas, Bracht, Tobias, Parker, Greg, Hall, Jeremy, Williams, Julie and Linden, David 2017. Multimodal brain imaging reveals structural differences in Alzheimer's disease polygenic risk carriers: A study in healthy young adults. Biological psychiatry 81 (2) , pp. 154-161. 10.1016/j.biopsych.2016.02.033

Morgan, Angharad, Touchard, Samuel, O'Hagan, Caroline, Sims, Rebecca, Majounie, Elisa, Escott-Price, Valentina, Jones, Lesley, Williams, Julie and Morgan, Bryan 2017. The correlation between inflammatory biomarkers and polygenic risk score in Alzheimer's Disease. Journal of Alzheimer's Disease 56 (1) , pp. 25-36. 10.3233/JAD-160889

Escott-Price, Valentina, Shoai, Maryam, Pither, Richard, Williams, Julie and Hardy, John 2017. Polygenic score prediction captures nearly all common genetic risk for Alzheimer's disease. Neurobiology of Aging 49 , 214.e7-214.e11. 10.1016/j.neurobiolaging.2016.07.018

Jakobsdottir, Johanna, van der Lee, Sven J., Bis, Joshua C., Chouraki, Vincent, Li-Kroeger, David, Yamamoto, Shinya, Grove, Megan L., Naj, Adam, Vronskaya, Maria, Salazar, Jose L., DeStefano, Anita L., Brody, Jennifer A., Smith, Albert V., Amin, Najaf, Sims, Rebecca, Ibrahim-Verbaas, Carla A., Choi, Seung-Hoan, Satizabal, Claudia L., Lopez, Oscar L., Beiser, Alexa, Ikram, M. Arfan, Garcia, Melissa E., Hayward, Caroline, Varga, Tibor V., Ripatti, Samuli, Franks, Paul W., Hallmans, Göran, Rolandsson, Olov, Jansson, Jan-Håkon, Porteous, David J., Salomaa, Veikko, Eiriksdottir, Gudny, Rice, Kenneth M., Bellen, Hugo J., Levy, Daniel, Uitterlinden, Andre G., Emilsson, Valur, Rotter, Jerome I., Aspelund, Thor, O'Donnell, Christopher J., Fitzpatrick, Annette L., Launer, Lenore J., Hofman, Albert, Wang, Li-San, Williams, Julie, Schellenberg, Gerard D., Boerwinkle, Eric, Psaty, Bruce M., Seshadri, Sudha, Shulman, Joshua M., Gudnason, Vilmundur and van Duijn, Cornelia M. 2016. Rare functional variant in TM2D3 is associated with late-onset Alzheimer's disease. PLoS Genetics 12 (10) , e1006327. 10.1371/journal.pgen.1006327

Thomas, Rhian, Henson, Alexander, Gerrish, Amy, Jones, Lesley, Williams, Julie and Kidd, Emma Jane 2016. Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease. BMC Neuroscience 17 , 50. 10.1186/s12868-016-0288-1

Traylor, Matthew, Adib-Samii, Poneh, Harold, Denise, Dichgans, Martin, Williams, Julie, Lewis, Cathryn M. and Markus, Hugh S. 2016. Shared genetic contribution to ischemic stroke and Alzheimer's disease. Annals of Neurology 79 (5) , pp. 739-747. 10.1002/ana.24621

Sims, Rebecca and Williams, Julie 2016. Defining the genetic architecture of Alzheimer's Disease: where next. Neurodegenerative Diseases 16 (1-2) 10.1159/000440841

Escott-Price, Valentina, Sims, Rebecca, Bannister, Christian, Harold, Denise, Vronskaya, Maria, Majounie, Elisa, Badarinarayan, Nandini, Morgan, Kevin, Passmore, Peter, Holmes, Clive, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Goate, Alison, Cruchaga, Carlos, Lambert, Jean-Charles, van Duijn, Cornelia, Maier, Wolfgang, Ramirez, Alfredo, Holmans, Peter Alan, Jones, Lesley, Hardy, John, Seshadri, Sudha, Schellenberg, Gerard D., Amouyel, Philippe and Williams, Julie 2015. Common polygenic variation enhances risk prediction for Alzheimer's disease. Brain 138 (12) , pp. 3673-3684. 10.1093/brain/awv268

Lancaster, Thomas, Brindley, Lisa, Tansey, Katherine, Sims, Rebecca, Mantripragada, Kiran Kumar, Owen, Michael John, Williams, Julie and Linden, David Edmund Johannes 2015. Alzheimer's disease risk variant in CLU is associated with neural inefficiency in healthy individuals. Alzheimer's & Dementia 11 (10) , pp. 1144-1152. 10.1016/j.jalz.2014.10.012

Østergaard, Søren D., Mukherjee, Shubhabrata, Sharp, Stephen J., Proitsi, Petroula, Lotta, Luca A., Day, Felix, Perry, John R. B., Boehme, Kevin L., Walter, Stefan, Kauwe, John S., Gibbons, Laura E., Alzheimer's Disease Genetics Consortium, , EPIC-InterAct Consortium, , Larson, Eric B., Powell, John F., Langenberg, Claudia, Crane, Paul K., Wareham, Nicholas J., Scott, Robert A., Sims, Rebecca, Gerrish, Amy, Hamshere, Marian L., Escott-Price, Valentina, Badarinarayan, Nandini, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John and Williams, Julie 2015. Associations between potentially modifiable risk factors and Alzheimer disease: A mendelian randomization study. PLOS MEDICINE 12 (6) , e1001841. 10.1371/journal.pmed.1001841

Jones, Lesley, Lambert, J-C., Wang, L-S., Choi, S-H., Harold, Denise, Vedernikov, Alexey, Escott-Price, Valentina, Stone, Timothy C., Richards, Alexander, Bellenguez, C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, Rebecca, Gerrish, Amy, Jun, G., DeStefano, A. L., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Denning, Nicola, Smith, A. V., Chouraki, V., Thomas, Charlene, Ikram, M. A., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C-F., Schmidt, H., Kunkle, B. W., Dunstan, Melanie, Ruiz, A., Bihoreau, M-T., Reitz, C., Pasquier, F., Hollingworth, P., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letteneur, L., Kornhuber, J., Tarraga, L., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fievet, N., Heuntelman, M. J., Gill, M., Emilsson, V., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Myers, A. J., Dufoil, C., Todd, S., Wallon, D., Love, S., Kehoe, P., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, Antony, Tsuang, D. W., Yu, L., Tsolaki, M., Bossu, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez Garcia, F., Fox, N., Hardy, J., Deniz Naranjo, M. C., Razquin, C., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Mancuso, M., Moebus, S., Mecocci, P., del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Jessen, F., Dichgans, M., Lannfelt, L., Hakonarson, H., Pichier, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alavarez, V., Zou, F., Valadares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Mateo, I., Owen, Michael John, Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, Michael Conlon, Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley Jr., T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., de Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Faroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boenwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Pastor, P., Schmidt, R., Rujescu, D., Dartigues, J-F., Mayeaux, R., Tzourio, C., Hofman, A., Nothen, M. M., Graff, C., Psaty, B. W., Haines, J. L., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farren, L. A., van Duijn, C. M., Van Broeckhoven, C., Ramirez, A., Schellenberg, G. D., Seshadri, S., Amouye, P., Williams, Julie and Holmans, Peter Alan 2015. Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's and Dementia 11 (6) , pp. 658-671. 10.1016/j.jalz.2014.05.1757

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Mok, Kin Y., Jones, Emma L., Hanney, Marisa, Harold, Denise, Sims, Rebecca, Williams, Julie, Ballard, Clive and Hardy, John 2014. Polymorphisms in BACE2 may affect the age of onset Alzheimer's dementia in Down syndrome. Neurobiology of Aging 35 (6) , 1513.e1-5. 10.1016/j.neurobiolaging.2013.12.022

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Williams, Pete A., Thirgood, Rebecca A., Oliphant, Huw, Frizzati, Aura, Littlewood, Elinor, Votruba, Marcela, Good, Mark Andrew, Williams, Julie and Morgan, James Edwards 2013. Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease. Neurobiology of Aging 34 (7) , pp. 1799-1806. 10.1016/j.neurobiolaging.2013.01.006

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Cruchaga, Carlos, Kauwe, John S. K., Harari, Oscar, Jin, Sheng Chih, Cai, Yefei, Karch, Celeste M., Benitez, Bruno A., Jeng, Amanda T., Skorupa, Tara, Carrell, David, Bertelsen, Sarah, Bailey, Matthew, McKean, David, Shulman, Joshua M., De Jager, Philip L., Chibnik, Lori, Bennett, David A., Arnold, Steve E., Harold, Denise, Sims, Rebecca, Gerrish, Amy, Williams, Julie, Van Deerlin, Vivianna M., Lee, Virginia M.-Y., Shaw, Leslie M., Trojanowski, John Q., Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Peskind, Elaine R., Galasko, Douglas, Fagan, Anne M., Holtzman, David M., Morris, John C. and Goate, Alison M. 2013. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron 78 (2) , pp. 256-268. 10.1016/j.neuron.2013.02.026

Lambert, J. C., Grenier-Boley, B., Harold, Denise, Zelenika, D., Chouraki, V., Kamatani, Y., Sleegers, K., Ikram, M. A., Hiltunen, M., Reitz, C., Mateo, I., Feulner, T., Bullido, M., Galimberti, D., Concari, L., Alvarez, V., Sims, Rebecca, Gerrish, Amy, Chapman, Jade Alice, Deniz-Naranjo, C., Solfrizzi, V., Sorbi, S., Arosio, B., Spalletta, G., Siciliano, G., Epelbaum, J., Hannequin, D., Dartigues, J. F., Tzourio, C., Berr, C., Schrijvers, E. M. C., Rogers, R., Tosto, G., Pasquier, F., Bettens, K., Van Cauwenberghe, C., Fratiglioni, L., Graff, C., Delepine, M., Ferri, R., Reynolds, C. A., Lannfelt, L., Ingelsson, M., Prince, J. A., Chillotti, C., Pilotto, A., Seripa, D., Boland, A., Mancuso, M., Bossù, P., Annoni, G., Nacmias, B., Bosco, P., Panza, F., Sanchez-Garcia, F., Del Zompo, M., Coto, E., Owen, Michael John, O'Donovan, Michael Conlon, Valdivieso, F., Caffara, P., Scarpini, E., Combarros, O., Buée, L., Campion, D., Soininen, H., Breteler, M., Riemenschneider, M., Van Broeckhoven, C., Alpérovitch, A., Lathrop, M., Trégouët, D. A., Williams, Julie and Amouyel, P. 2013. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease [Correction]. Molecular Psychiatry 18 (4) , p. 521. 10.1038/mp.2012.75

Chapman, J., Rees, Elliott, Harold, Denise, Ivanov, Dobril, Gerrish, Amy, Sims, Rebecca, Hollingworth, P, Stretton, A., Holmans, Peter Alan, Owen, Michael John, O'Donovan, Michael Conlon, Williams, Julie and Kirov, George 2013. A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk. Human Molecular Genetics 22 (4) , pp. 816-824. 10.1093/hmg/dds476

Lee, S., Harold, Denise, Nyholt, D., Goddard, M., Zondervan, K., Williams, Julie, Montgomery, G., Wray, N. and Visscher, P. 2013. Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis. Human Molecular Genetics 22 (4) , pp. 832-841. 10.1093/hmg/dds491

Escott-Price, Valentina, Harold, Denise, Russo, Giancarlo, Vedernikov, Alexey, Sharma, Manu, Saad, Mohamad, Holmans, Peter Alan, Bras, Jose M., Bettella, Francesco, Keller, Margaux F., Nicolaou, Nayia, Simón-Sánchez, Javier, Gibbs, J. Raphael, Schulte, Claudia, Durr, Alexandra, Guerreiro, Rita, Hernandez, Dena, Brice, Alexis, Stefánsson, Hreinn, Majamaa, Kari, Gasser, Thomas, Heutink, Peter, Wood, Peter, Martinez, Maria, Singleton, Andrew B., Nalls, Michael A., Hardy, John, Owen, Michael John, O’Donovan, Michael Conlon, Williams, Julie, Morris, Huw and Williams, Nigel Melville 2013. Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk. JAMA Neurology 70 (10) , pp. 1268-1276. 10.1001/jamaneurol.2013.448

Guerreiro, Rita, Wojtas, Aleksandra, Bras, Jose, Carrasquillo, Minerva, Rogaeva, Ekaterina, Majounie, Elisa, Cruchaga, Carlos, Sassi, Celeste, Kauwe, John S.K., Younkin, Steven, Hazrati, Lilinaz, Collinge, John, Pocock, Jennifer, Lashley, Tammaryn, Williams, Julie, Lambert, Jean-Charles, Amouyel, Philippe, Goate, Alison, Rademakers, Rosa, Morgan, Kevin, Powell, John, St. George-Hyslop, Peter, Singleton, Andrew and Hardy, John 2013. TREM2Variants in Alzheimer's disease. New England Journal of Medicine 368 (2) , pp. 117-127. 10.1056/NEJMoa1211851

Brayne, Carol, Barker, Roger A., Harold, Denise, Ince, Paul G., Sawa, George M., Williams, Julie, Williams-Gray, Caroline H. and Wharton, Stephen B. 2013. From molecule to clinic and community for neurodegeneration: research to bridge translational gaps. Journal of Alzheimer's Disease 33 (Supp 1) , S385-S396. 10.3233/JAD-2012-129006

Jones, Emma L., Mok, Kin, Hanney, Marisa, Harold, Denise, Sims, Rebecca, Williams, Julie and Ballard, Clive 2013. Evidence that PICALM affects age at onset of Alzheimer's dementia in Down syndrome. Neurobiology of Aging 34 (10) , p. 2441. 10.1016/j.neurobiolaging.2013.03.018

Chapuis, J, Hansmannel, F, Gistelinck, M, Mounier, A, Van Cauwenberghe, C, Kolen, K V, Geller, F, Sottejeau, Y, Harold, D, Dourlen, P, Grenier-Boley, B, Kamatani, Y, Delepine, B, Demiautte, F, Zelenika, D, Zommer, N, Hamdane, M, Bellenguez, C, Dartigues, J-F, Hauw, J-J, Letronne, F, Ayral, A-M, Sleegers, K, Schellens, A, Broeck, L V, Engelborghs, S, De Deyn, P P, Vandenberghe, R, O'Donovan, Michael Conlon, Owen, Michael John, Epelbaum, J, Mercken, M, Karran, E, Bantscheff, M, Drewes, G, Joberty, G, Campion, D, Octave, J-N, Berr, C, Lathrop, M, Callaerts, P, Mann, D, Williams, Julie, Buée, L, Dewachter, I, Van Broeckhoven, C, Amouyel, P, Moechars, D, Dermaut, B and Lambert, J-C 2013. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology [Article]. Molecular Psychiatry 18 (11) , pp. 1225-1234. 10.1038/mp.2013.1

Hollingworth, Paul, Sweet, R., Sims, Rebecca, Harold, Denise, Russo, Giancarlo, Abraham, Richard Alun, Stretton, Alexandra, Denning, Nicola, Gerrish, Amy, Chapman, Jade Alice, Ivanov, Dobril, Escott-Price, Valentina, Lovestone, S., Priotsi, P., Lupton, M., Brayne, C., Gill, M., Lawlor, B., Lynch, A., Craig, D., McGuinness, B., Johnston, J., Holmes, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Holmans, Peter Alan, Jones, Lesley, Devlin, B., Klei, L., Barmada, M. M., Demirci, F. Y., DeKosky, S. T., Lopez, O. L., Passmore, P., Owen, Michael John, O'Donovan, Michael Conlon, Mayeux, R., Kamboh, M. I. and Williams, Julie 2012. Genome-wide association study of Alzheimer's disease with psychotic symptoms. Molecular Psychiatry 17 (12) , pp. 1316-1327. 10.1038/mp.2011.125

Hamilton, Gillian, Harris, Sarah E., Davies, Gail, Liewald, David C., Tenesa, Albert, Payton, Antony, Horan, Michael A., Ollier, William E.R., Pendleton, Neil, Starr, John M., Porteous, David, Deary, Ian J., Denning, Nicola, Escott-Price, Valentina, Gerrish, Amy, Hamshere, Marian Lindsay, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John, Sims, Rebecca, Thomas, Charlene and Williams, Julie 2012. The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B (6) , pp. 696-709. 10.1002/ajmg.b.32073

Hamilton, Gillian, Killick, Richard, Lambert, Jean-Charles, Amouyel, Philippe, Carrasquillo, Minerva M., Pankratz, V. Shane, Graff-Radford, Neill R., Dickson, Dennis W., Petersen, Ronald C., Younkin, Steven G., Powell, John F., Wade-Martins, Richard, Chapman, Jade, Denning, Nicola, Escott-Price, Valentina, Gerrish, Amy, Hamshere, Marian Lindsay, Harold, Denise, Hollingworth, Paul, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John, Pahwa, Jaspreet, Russo, Giancarlo, Sims, Rebecca, Thomas, Charlene and Williams, Julie 2012. Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiology of Aging 33 (8) , 1848.e1. 10.1016/j.neurobiolaging.2012.02.005

Shi, Hui, Belbin, Olivia, Medway, Christopher, Brown, Kristelle, Kalsheker, Noor, Carrasquillo, Minerva, Proitsi, Petroula, Powell, John, Lovestone, Simon, Goate, Alison, Younkin, Steven, Passmore, Peter, Morgan, Kevin, Chapman, Jade, Denning, Nicola, Escott-Price, Valentina, Gerrish, Amy, Hamshere, Marian Lindsay, Harold, Denise, Hollingworth, Paul, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John, Pahwa, Jaspreet, Sims, Rebecca, Thomas, Charlene and Williams, Julie 2012. Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS). Neurobiology of Aging 33 (8) , 1849.e5. 10.1016/j.neurobiolaging.2012.02.014

Proitsi, Petroula, Lupton, Michelle K., Dudbridge, Frank, Tsolaki, Magda, Hamilton, Gillian, Daniilidou, Makrina, Pritchard, Megan, Lord, Kathryn, Martin, Belinda M., Craig, David, Todd, Stephen, McGuinness, Bernadette, Hollingworth, Paul, Harold, Denise, Kloszewska, Iwona, Soininen, Hilkka, Mecocci, Patrizia, Velas, Bruno, Gill, Michael, Lawlor, Brian, Rubinsztein, David C., Brayne, Carol, Passmore, Peter A., Williams, Julie, Lovestone, Simon and Powell, John F. 2012. Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation [Abstract]. Neurobiology of Aging 33 (8) , 1843.e9-1843.e17. 10.1016/j.neurobiolaging.2011.12.036

Hudson, G., Sims, Rebecca, Harold, Denise, Chapman, Jade Alice, Hollingworth, Paul, Gerrish, Amy, Russo, Giancarlo, Hamshere, Marian Lindsay, Escott-Price, Valentina, Denning, Nicola, Thomas, Charlene, Stretton, Alexandra, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John, Williams, Julie and Chinnery, P. F. 2012. No consistent evidence for association between mtDNA variants and Alzheimer disease. Neurology 78 (14) , pp. 1038-1042. 10.1212/WNL.0b013e31824e8f1d

Lambert, J. C., Grenier-Boley, B., Harold, Denise, Zelenika, D., Chouraki, V., Kamatani, Y., Sleegers, K., Ikram, M. A., Hiltunen, M., Reitz, C., Mateo, I., Feulner, T., Bullido, M., Galimberti, D., Concari, L., Alvarez, V., Sims, Rebecca, Gerrish, Amy, Chapman, Jade Alice, Deniz-Naranjo, C., Solfrizzi, V., Sorbi, S., Arosio, B., Spalletta, G., Siciliano, G., Epelbaum, J., Hannequin, D., Dartigues, J. F., Tzourio, C., Berr, C., Schrijvers, E. M. C., Rogers, R., Tosto, G., Pasquier, F., Bettens, K., Van Cauwenberghe, C., Fratiglioni, L., Graff, C., Delepine, M., Ferri, R., Reynolds, C. A., Lannfelt, L., Ingelsson, M., Prince, J. A., Chillotti, C., Pilotto, A., Seripa, D., Boland, A., Mancuso, M., Bossù, P., Annoni, G., Nacmias, B., Bosco, P., Panza, F., Sanchez-Garcia, F., Del Zompo, M., Coto, E., Owen, Michael John, O'Donovan, Michael Conlon, Valdivieso, F., Caffara, P., Scarpini, E., Combarros, O., Buée, L., Campion, D., Soininen, H., Breteler, M., Riemenschneider, M., Van Broeckhoven, C., Alpérovitch, A., Lathrop, M., Trégouët, D. A., Williams, Julie and Amouyel, P. 2012. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Molecular Psychiatry 18 , pp. 461-470. 10.1038/mp.2012.14

Inkster, Becky, Rao, Anil W., Ridler, Khanum, Filippini, Nicola, Whitcher, Brandon, Nichols, Thomas E., Wetten, Sally, Gibson, Rachel A., Borrie, Michael, Kertesz, Andrew, Guzman, Danilo A., Loy-English, Inge, Williams, Julie, Saemann, Philipp G., Auer, Dorothee P., Holsboer, Florian, Tozzi, Federica, Muglia, Pierandrea, Merlo-Pich, Emilio and Matthews, Paul M. 2012. Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease. Neurobiology of Aging 33 (3) , pp. 457-465. 10.1016/j.neurobiolaging.2010.04.018

Gerrish, Amy, Russo, Giancarlo, Richards, Alexander, Escott-Price, Valentina, Ivanov, Dobril, Harold, Denise, Sims, Rebecca, Abraham, Richard Alun, Hollingworth, Paul, Chapman, Jade Alice, Hamshere, Marian Lindsay, Pahwa, Jaspreet Singh, Dowzell, Kimberley Frances, Williams, Amy, Denning, Nicola, Thomas, Charlene, Stretton, Alexandra, Morgan, Angharad Rhys, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuinness, Bernadette, Todd, Stephen, Johnston, Janet A., Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Hardy, John, Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Kölsch, Heike, Heun, Reinhard, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison M., Kauwe, John S. K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panagiotis, Davies, Gail, Harris, Sarah E., Starr, John M., Deary, Ian J., Al-Chalabi, Ammar, Shaw, Christopher E., Tsolaki, Magda, Singleton, Andrew B., Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H-Erich, Carrasquillo, Minerva M, Pankratz, V. Shane, Younkin, Steven G., Jones, Lesley, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John and Williams, Julie 2012. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's Disease. Journal of Alzheimer's Disease 28 (2) , pp. 377-387. 10.3233/JAD-2011-110824

Proitsi, Petroula, Lupton, Michelle K., Reeves, Suzanne J., Hamilton, Gillian, Archer, Nicola, Martin, Belinda M., Iyegbe, Conrad, Hollingworth, Paul, Lawlor, Brian, Gill, Michael, Brayne, Carol, Rubinsztein, David C., Owen, Michael John, Williams, Julie, Lovestone, Simon and Powell, John F. 2012. Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia. Neurobiology of Aging 33 (4) , pp. 791-803. 10.1016/j.neurobiolaging.2010.06.011

Hood, Kerenza, Robling, Michael Richard, Ingledew, D., Gillespie, David, Greene, Giles, Ivins, Rhys, Russell, I., Sayers, A., Shaw, C. and Williams, Julie 2012. Mode of data elicitation, acquisition and response to surveys: a systematic review. Health Technology Assessment 16 (27) 10.3310/hta16270

Baig, Shabnam, Palmer, Laura E., Owen, Michael John, Williams, Julie, Kehoe, Patrick G. and Love, Seth 2012. Clusterin mRNA and protein in Alzheimer's disease. Journal of Alzheimer's Disease 28 (2) , pp. 337-344. 10.3233/JAD-2011-110473

Williams, Julie 2011. Interview: Julie Williams speaks to Personalized Medicine. Personalized Medicine 8 (4) , pp. 393-395. 10.2217/pme.11.41

Hollingworth, Paul, Harold, Denise, Sims, Rebecca, Gerrish, Amy, Lambert, Jean-Charles, Carrasquillo, Minerva M., Abraham, Richard Alun, Hamshere, Marian Lindsay, Pahwa, Jaspreet Singh, Escott-Price, Valentina, Dowzell, Kimberley Frances, Denning, Nicola, Stretton, Alexandra, Thomas, Charlene, Richards, Alexander, Ivanov, Dobril, Widdowson, Caroline Susan, Chapman, Jade Alice, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A David, Beaumont, Helen, Warden, Donald, Wilcock, Gordon, Love, Seth, Kehoe, Patrick G., Hooper, Nigel M., Vardy, Emma R. L. C., Hardy, John, Mead, Simon, Fox, Nick C, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Rüther, Eckart, Schürmann, Britta, Heun, Reiner, Kölsch, Heike, van den Bussche, Hendrik, Heuser, Isabella, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Gallacher, John Edward, Hüll, Michael, Rujescu, Dan, Giegling, Ina, Goate, Alison M., Kauwe, John S. K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Sleegers, Kristel, Bettens, Karolien, Engelborghs, Sebastiaan, De Deyn, Peter P, Van Broeckhoven, Christine, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panagiotis, Al-Chalabi, Ammar, Shaw, Christopher E., Tsolaki, Magda, Singleton, Andrew B., Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H-Erich, Pankratz, V. Shane, Sando, Sigrid B., Aasly, Jan O., Barcikowska, Maria, Wszolek, Zbigniew K., Dickson, Dennis W., Graff-Radford, Neill R., Petersen, Ronald C., van Duijn, Cornelia M., Breteler, Monique M. B., Ikram, M. Arfan, DeStefano, Anita L., Fitzpatrick, Annette L., Lopez, Oscar, Launer, Lenore J., Seshadri, Sudha, Berr, Claudine, Campion, Dominique, Epelbaum, Jacques, Dartigues, Jean-François, Tzourio, Christophe, Alpérovitch, Annick, Lathrop, Mark, Feulner, Thomas M., Friedrich, Patricia, Riehle, Caterina, Krawczak, Michael, Schreiber, Stefan, Mayhaus, Manuel, Nicolhaus, S., Wagenpfeil, Stefan, Steinberg, Stacy, Stefansson, Hreinn, Stefansson, Kari, Snædal, Jon, Björnsson, Sigurbjörn, Jonsson, Palmi V., Chouraki, Vincent, Genier-Boley, Benjamin, Hiltunen, Mikko, Soininen, Hilkka, Combarros, Onofre, Zelenika, Diana, Delepine, Marc, Bullido, Maria J., Pasquier, Florence, Mateo, Ignacio, Frank-Garcia, Ana, Porcellini, Elisa, Hanon, Olivier, Coto, Eliecer, Alvarez, Victoria, Bosco, Paolo, Siciliano, Gabriele, Mancuso, Michelangelo, Panza, Francesco, Solfrizzi, Vincenzo, Nacmias, Benedetta, Sorbi, Sandro, Bossù, Paola, Piccardi, Paola, Arosio, Beatrice, Annoni, Giorgio, Seripa, Davide, Pilotto, Alberto, Scarpini, Elio, Galimberti, Daniela, Brice, Alexis, Hannequin, Didier, Licastro, Federico, Jones, Lesley, Holmans, Peter Alan, Jonsson, Thorlakur, Riemenschneider, Matthias, Morgan, Kevin, Younkin, Steven G., Owen, Michael John, O'Donovan, Michael Conlon, Amouyel, Philippe and Williams, Julie 2011. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics 43 (5) , pp. 429-435. 10.1038/ng.803

Schuermann, Britta, Wiese, Birgitt, Bickel, Horst, Weyerer, Siegfried, Riedel-Heller, Steffi G., Pentzek, Michael, Bachmann, Cadja, Williams, Julie, van den Bussche, Hendrik, Maier, Wolfgang and Jessen, Frank 2011. Association of the Alzheimer's disease clusterin risk allele with plasma clusterin concentration. Journal of Alzheimers Disease 25 (3) , pp. 421-424.

Belbin, Olivia, Brown, Kristelle, Shi, Hui, Medway, Christopher, Abraham, Richard, Passmore, Peter, Mann, David, Smith, A. David, Holmes, Clive, McGuinness, Bernadette, Craig, David, Warden, Donald, Heun, Reinhard, Koelsch, Heike, Love, Seth, Kalsheker, Noor, Williams, Julie, Owen, Michael John, Carrasquillo, Minerva, Younkin, Steven, Morgan, Kevin and Kehoe, Patrick G. 2011. A multi-center study of ACE and the risk of late-onset Alzheimer's disease. Journal of Alzheimer's Disease 24 (3) , pp. 587-597. 10.3233/JAD-2011-101914

Reitz, Christine, Cheung, Rong, Rogaeva, Ekaterina, Lee, Joseph H., Tokuhiro, Shinya, Zou, Fanggeng, Bettens, Karolien, Sleegers, Kristel, Tan, Eng King, Kimura, Ryo, Shibata, Nobuto, Arai, Heii, Kamboh, Ilyas, Prince, Jonathan A., Maier, Wolfgang, Riemenschneider, Matthias, Owen, Michael John, Harold, Denise, Hollingworth, Paul, Cellini, Elena, Sorbi, Sandro, Nacmias, Benedetta, Takeda, Masatoshi, Pericak-Vance, Margaret A., Haines, Jonathan L., Younkin, Steven, Williams, Julie, van Broeckhoven, Christine, Farrer, Lindsay, St George-Hyslop, Peter and Mayeux, Richard 2011. Meta-analysis of the association between variants in SORL1 and Alzheimer Disease. Archives of Neurology 68 (1) , pp. 99-106. 10.1001/archneurol.2010.346

Sims, Rebecca, Dwyer, Sarah Lynne, Harold, Denise, Gerrish, Amy, Hollingworth, Paul, Chapman, Jade Alice, Denning, Nicola, Abraham, Richard Alun, Ivanov, Dobril, Pahwa, Jaspreet Singh, Escott-Price, Valentina, Dowzell, Kimberley Frances, Thomas, Charlene, Stretton, Alexandra, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuiness, Bernadette, Todd, Stephen, Johnston, Janet A., Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Hardy, John, Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Jones, Lesley, Holmans, Peter Alan, O'Donovan, Michael Conlon, Owen, Michael John and Williams, Julie 2011. No evidence that extended tracts of homozygosity are associated with Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156 (7) , pp. 764-771. 10.1002/ajmg.b.31216

Jones, Lesley, Holmans, Peter Alan, Hamshere, Marian Lindsay, Harold, Denise, Escott-Price, Valentina, Ivanov, Dobril, Pocklington, Andrew, Abraham, Richard Alun, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Pahwa, Jaspreet Singh, Denning, Nicola, Stretton, Alexandra, Morgan, Angharad Rhys, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, Heun, Reinhard, Kölsch, Heike, van den Bussche, Hendrik, Heuser, Isabella, Peters, Oliver, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison M., Kauwe, John S. K., Cruchaga, Carlos, Nowotny, Petra, Mayo, Kevin, Morris, John C., Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panos, Al-Chalabi, Ammar, Shaw, Christopher E., Singleton, Andrew B., Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H.-Erich, Rüther, Eckhard, Carrasquillo, Minerva M., Pankratz, V. Shane, Younkin, Steven G., Hardy, John, O'Donovan, Michael Conlon, Williams, Julie and Owen, Michael John 2010. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS ONE 5 (11) , e13950. 10.1371/journal.pone.0013950

Pagnamenta, Alistair T., Bacchelli, Elena, de Jonge, Maretha V., Mirza, Ghazala, Scerri, Thomas S., Minopoli, Fiorella, Chiocchetti, Andreas, Ludwig, Kerstin U., Hoffmann, Per, Paracchini, Silvia, Lowy, Ernesto, Harold, Denise, Chapman, Jade Alice, Klauck, Sabine M., Poustka, Fritz, Houben, Renske H., Staal, Wouter G., Ophoff, Roel A., O'Donovan, Michael Conlon, Williams, Julie, Nöthen, Markus M., Schulte-Körne, Gerd, Deloukas, Panos, Ragoussis, Jiannis, Bailey, Anthony J., Maestrini, Elena and Monaco, Anthony P. 2010. Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biological psychiatry 68 (4) , pp. 320-328. 10.1016/j.biopsych.2010.02.002

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Lupton, Michelle K, Stahl, Daniel, Archer, Nicola, Foy, Catherine, Poppe, Michaela, Lovestone, Simon, Hollingworth, Paul, Williams, Julie, Owen, Michael John, Dowzell, Kimberley Frances, Abraham, Richard Alun, Sims, Rebecca, Brayne, Carol, Rubinsztein, David, Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn and Powell, John F 2010. Education, occupation and retirement age effects on the age of onset of Alzheimer's disease. International Journal of Geriatric Psychiatry 25 (1) , pp. 30-36. 10.1002/gps.2294

Jones, Lesley, Harold, Denise and Williams, Julie 2010. Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1801 (8) , pp. 754-761. 10.1016/j.bbalip.2010.04.005

Cruchaga, Carlos, Kauwe, John S. K., Mayo, Kevin, Spiegel, Noah, Bertelsen, Sarah, Nowotny, Petra, Shah, Aarti R., Abraham, Richard, Hollingworth, Paul, Harold, Denise, Owen, Michael John, Williams, Julie, Lovestone, Simon, Peskind, Elaine R., Li, Ge, Leverenz, James B., Galasko, Douglas, Morris, John C., Fagan, Anne M., Holtzman, David M. and Goate, Alison M. 2010. SNPS associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. PLoS Genetics 6 (9) , e1001101. 10.1371/journal.pgen.1001101

Baig, Shabnam, Joseph, Sally A., Tayler, Hannah, Abraham, Richard Alun, Owen, Michael John, Williams, Julie, Kehoe, Patrick G. and Love, Seth 2010. Distribution and expression of picalm in alzheimer disease. Journal of Neuropathology and Experimental Neurology 69 (10) , pp. 1071-1077. 10.1097/NEN.0b013e3181f52e01

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Abraham, Richard Alun, Sims, Rebecca, Carroll, Liam Stuart, Hollingworth, Paul, O'Donovan, Michael Conlon, Williams, Julie and Owen, Michael John 2009. An association study of common variation at theMAPTlocus with late-onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B (8) , pp. 1152-1155. 10.1002/ajmg.b.30951

Kauwe, J. S. K., Bertelsen, S., Mayo, K., Cruchaga, C., Abraham, Richard Alun, Hollingworth, Paul, Harold, Denise, Owen, Michael John, Williams, Julie, Lovestone, S., Morris, J. C. and Goate, A. M. 2009. Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B (4) , pp. 955-959. 10.1002/ajmg.b.31053

Filippini, Nicola, Rao, Anil, Wetten, Sally, Gibson, Rachel A., Borrie, Michael, Guzman, Danilo, Kertesz, Andrew, Loy-English, Inge, Williams, Julie, Nichols, Thomas, Whitcher, Brandon and Matthews, Paul M. 2009. Anatomically-distinctgeneticassociations of APOE ɛ4 alleleload with regionalcorticalatrophy in Alzheimer's disease. NeuroImage 44 (3) , pp. 724-728. 10.1016/j.neuroimage.2008.10.003

Blom, Elin S., Giedraitis, Vilmantas, Arepalli, Sampath, Hamshere, Marian Lindsay, Adighibe, Omanma, Goate, Alison, Williams, Julie, Lannfelt, Lars, Hardy, John, Vrièze, Fabienne and Glaser, Anna 2009. Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs. BMC Medical Genetics 10 , pp. 1-6. 10.1186/1471-2350-10-122

Abraham, Richard, Escott-Price, Valentina, Sims, Rebecca, Hollingworth, Paul, Morgan, Angharad, Georgieva, Lyudmila, Dowzell, Kimberley, Cichon, Sven, Hillmer, Axel M, O'Donovan, Michael Conlon, Williams, Julie, Owen, Michael John and Kirov, George 2008. A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Medical Genomics 1 (1) , 44. 10.1186/1755-8794-1-44

Li, Hao, Wetten, Sally, Li, Li, St. Jean, Pamela L., Upmanyu, Ruchi, Surh, Linda, Hosford, David, Barnes, Michael R., Briley, James David, Borrie, Michael, Coletta, Natalie, Delisle, Richard, Dhalla, Daniella, Ehm, Margaret G., Feldman, Howard H., Fornazzari, Luis, Gauthier, Serge, Goodgame, Neil, Guzman, Danilo, Hammond, Sandra, Hollingworth, Paul, Hsiung, Ging - Yuek, Johnson, Joan, Kelly, Devon D., Keren, Ron, Kertesz, Andrew, King, Karen S., Lovestone, Simon, Loy-English, Inge, Matthews, Paul M., Owen, Michael John, Plumpton, Mary, Pryse-Phillips, William, Prinjha, Rab K., Richardson, Jill C., Saunders, Ann, Slater, Andrew J., St. George-Hyslop, Peter H., Stinnett, Sandra W., Swartz, Jina E., Taylor, Rachel L., Wherrett, John, Williams, Julie, Yarnall, David P., Gibson, Rachel A., Irizarry, Michael C., Middleton, Lefkos T. and Roses, Allen D. 2008. Candidate single-nucleotide polymorphisms from a genomewide association study of alzheimer disease. Archives of Neurology 65 (1) , pp. 45-53. 10.1001/archneurol.2007.3

Kwok, John B. J., Loy, Clement T., Hamilton, Gillian, Lau, Edmond, Hallupp, Marianne, Williams, Julie, Owen, Michael John, Broe, G. Anthony, Tang, Nelson, Lam, Linda, Powell, John F., Lovestone, Simon and Schofield, Peter R. 2008. Glycogen synthase kinase-3β and tau genes interact in Alzheimer's disease. Annals of Neurology 64 (4) , pp. 446-454. 10.1002/ana.21476

Li, Y., Grupe, A., Rowland, C., Holmans, Peter Alan, Segurado, Ricardo, Abraham, Richard Alun, Jones, Lesley, Catanese, J., Ross, D., Mayo, K., Martinez, M., Hollingworth, Paul, Goate, A., Cairns, N. J., Racette, B. A., Perlmutter, J. S., O'Donovan, Michael Conlon, Morris, J. C., Brayne, C., Rubinsztein, D. C., Lovestone, S., Thal, L. J., Owen, Michael John and Williams, Julie 2008. Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. Human Molecular Genetics 17 (5) , pp. 759-767. 10.1093/hmg/ddm348

Blom, Elin S., Holmans, Peter Alan, Arepalli, Sampath, Adighibe, Omanma, Hamshere, Marian Lindsay, Gatz, Margaret, Pedersen, Nancy L., Bergem, A. L. Mina, Owen, Michael John, Hollingworth, Paul, Goate, Alison, Williams, Julie, Lannfelt, Lars, Hardy, John, Wavrant-De Vrièze, Fabienne and Glaser, Anna 2008. Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B (6) , pp. 778-783. 10.1002/ajmg.b.30681

Foy, Catherine M. L., Nicholas, Helen, Hollingworth, Paul, Boothby, Harry, Williams, Julie, Brown, Richard G., Al-Sarraj, Safa and Lovestone, Simon 2007. Diagnosing Alzheimer's disease--non-clinicians and computerised algorithms together are as accurate as the best clinical practice. International Journal of Geriatric Psychiatry 22 (11) , pp. 1154-1163. 10.1002/gps.1810

Hollingworth, Paul, Hamshere, Marian Lindsay, Holmans, Peter Alan, O'Donovan, Michael Conlon, Sims, Rebecca, Powell, J., Lovestone, S., Myers, A., DeVrieze, F.W., Hardy, J., Goate, A., Owen, Michael John and Williams, Julie 2007. Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B (7) , pp. 841-848. 10.1002/ajmg.b.30515

Morgan, A.R., Turic, Darko, Jehu, Luke, Hamilton, G., Hollingworth, Paul, Escott-Price, Valentina, Jones, Lesley, Lovestone, S., Brayne, C., Rubinsztein, D.C., Lawlor, B., Gill, M., O'Donovan, Michael Conlon, Owen, Michael John and Williams, Julie 2007. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B (6) , pp. 762-770. 10.1002/ajmg.b.30509

Hamshere, Marian Lindsay, Holmans, Peter Alan, Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, Wiener, Howard, Rochberg, Nan, Tanzi, Rudolph E., Myers, Amanda, Wavrant-De Vrièze, Fabienne, Go, Rodney, Fallin, Daniele, Lovestone, Simon, Hardy, John, Goate, Alison, O'Donovan, Michael Conlon, Williams, Julie and Owen, Michael John 2007. Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. Human Molecular Genetics Advanc , pp. 1-34. 10.1093/hmg/ddm224

Harold, Denise, Jehu, Luke, Turic, Darko, Hollingworth, Paul, Moore, P., Summerhayes, P., Escott-Price, Valentina, Foy, C., Archer, N., Hamilton, B.A., Lovestone, S., Powell, J., Brayne, C., Rubinsztein, D.C., Jones, Lesley, O'Donovan, Michael Conlon, Owen, Michael John and Williams, Julie 2007. Interaction between theADAM12 andSH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B (4) , pp. 448-452. 10.1002/ajmg.b.30456

Hamilton, Gillian, Proitsi, Petra, Jehu, Luke, Morgan, Angharad, Williams, Julie, O'Donovan, Michael Conlon, Owen, Michael John, Powell, John F. and Lovestone, Simon 2007. Candidate gene association study of insulin signaling genes and Alzheimer's disease: Evidence for SOS2, PCK1, and PPARgamma as susceptibility loci. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B (4) , pp. 508-516. 10.1002/ajmg.b.30503

Archer, Nicola, Brown, Richard G., Reeves, Suzanne J., Boothby, Harry, Nicholas, Helen, Foy, Catherine, Williams, Julie and Lovestone, Simon 2007. Premorbid personality and behavioral and psychological symptoms in probable Alzheimer disease. American Journal of Geriatric Psychiatry 15 (3) , pp. 202-213.

Grupe, Andrew, Abraham, Richard Alun, Li, Yonghong, Rowland, Charles, Hollingworth, Paul, Morgan, Angharad Rhys, Jehu, Luke, Segurado, Ricardo, Stone, David, Schadt, Eric, Karnoub, Maha, Nowotny, Petra, Tacey, Kristina, Catanese, Joseph, Sninsky, John, Brayne, Carol, Rubinsztein, David, Gill, Michael, Lawlor, Brian, Lovestone, Simo, Holmans, Peter Alan, O'Donovan, Michael Conlon, Morris, John C., Thal, Leon, Goate, Alison, Owen, Michael John and Williams, Julie 2007. Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Human Molecular Genetics 16 (8) , pp. 865-873. 10.1093/hmg/ddm031

Hamilton, Gillian, Proitsi, Petra, Williams, Julie, O'Donovan, Michael Conlon, Owen, Michael John, Powell, John and Lovestone, Simon 2007. Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease. Neuromolecular Medicine 9 (4) , pp. 331-334. 10.1007/s12017-007-8013-y

Morgan, A.R., Hamilton, G., Turic, Dragana, Jehu, L., Harold, Denise, Abraham, Richard Alun, Hollingworth, Paul, Escott-Price, Valentina, Brayne, C., Rubinsztein, D.C., Lynch, A., Lawlor, B., Gill, M., O'Donovan, Michael Conlon, Powell, J., Lovestone, S., Williams, Julie and Owen, Michael John 2007. Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B (6) , pp. 727-731. 10.1002/ajmg.b.30670

Hollingworth, Paul, Hamshere, Marian Lindsay, Escott-Price, Valentina, Dowzell, Kimberley, Moore, Pamela J., Foy, Catherine, Archer, Nicola, Lynch, Aoibhinn, Lovestone, Simon, Brayne, Carol, Rubinsztein, David C., Lawlor, Brian, Gill, Mike, Owen, Michael John and Williams, Julie 2006. Four Components Describe Behavioral Symptoms in 1,120 Individuals with Late-Onset Alzheimer's Disease. Journal of the American Geriatrics Society 54 (9) , pp. 1348-1354. 10.1111/j.1532-5415.2006.00854.x

Li, Yonghong, O'Donovan, Michael Conlon, Williams, Julie, Brayne, Carol, Rowland, Charles, Owen, Michael John, Morris, John C and Maxwell, Taylor J 2006. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Human Molecular Genetics 15 (17) , pp. 2560-2568. 10.1093/hmg/ddl178

Williams, Julie and O'Donovan, Michael Conlon 2006. The genetics of developmental dyslexia. European Journal of Human Genetics 14 (6) , pp. 681-89. 10.1038/sj.ejhg.5201575

Hamilton, Gillian, Samedi, Farzana, Knight, Jo, Archer, Nicola, Foy, Catherine, Walter, Sarah, Turic, Dragana, Jehu, Luke, Moore, Pamela, Hollingworth, Paul, O'Donovan, Michael Conlon, Williams, Julie, Owen, Michael John, Lovestone, Simon and Powell, John F. 2006. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neuroscience Letters 401 (1-2) , pp. 77-80. 10.1016/j.neulet.2006.03.021

Harold, Denise, Macgregor, S., Patterson, C. E., Hollingworth, P., Moore, P., Owen, Michael John, Williams, Julie, O'Donovan, Michael Conlon, Passmore, P., McIlroy, S. and Jones, Lesley 2006. A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease. Pharmacogenetics and genomics 16 (2) , pp. 75-77.

Grupe, Andrew, Li, Yonghong, Rowland, Charles, Nowotny, Petra, Hinrichs, Anthony L., Smemo, Scott, Kauwe, John S. K., Maxwell, Taylor J., Cherny, Sara, Doil, Lisa, Tacey, Kristina, Luchene, Ryan van, Myers, Amanda, Wavrant-De Vrièze, Fabienne, Kaleem, Mona, Hollingworth, Paul, Jehu, Luke, Foy, Catherine, Archer, Nicola, Hamilton, Gillian, Holmans, Peter Alan, Morris, Chris M., Catanese, Joseph, Sninsky, John, White, Thomas J., Powell, John, Hardy, John, O'Donovan, Michael Conlon, Lovestone, Simon, Jones, Lesley, Morris, John C., Thal, Leon, Owen, Michael John, Williams, Julie and Goate, Alison 2006. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. The American Journal of Human Genetics 78 (1) , pp. 78-88.

Li, Y., Rowland, C., Tacey, K., Catanese, J., Sninsky, J., Hardy, J., Powell, J., Lovestone, S., Morris, J. C., Thal, L., Goate, A., Owen, Michael John, Williams, Julie and Grupe, A. 2005. The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples. Molecular Psychiatry 10 (9) , pp. 809-810. 10.1038/sj.mp.4001702

Holmans, Peter Alan, Hamshere, Marian Lindsay, Hollingworth, P., Rice, Frances, Tunstall, N., Jones, S., Moore, P., Wavrant DeVrieze, F., Myers, A., Crook, R., Compton, D., Marshall, H., Meyer, D., Shears, S., Booth, J., Ramic, D., Williams, Nigel Melville, Norton, N., Abraham, R., Kehoe, P., Williams, H., Rudrasingham, V., O'Donovan, Michael Conlon, Jones, Lesley, Hardy, J., Goate, A., Lovestone, S., Owen, Michael John and Williams, Julie 2005. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 135B (1) , pp. 24-32. 10.1002/ajmg.b.30114

Cope, Natalie Alexandra, Harold, Denise, Hill, Gary Trevor, Escott-Price, Valentina, Stevenson, Jim, Holmans, Peter Alan, Owen, Michael John, O’Donovan, Michael Conlon and Williams, Julie 2005. Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. American Journal of Human Genetics 76 (4) , pp. 581-591. 10.1086/429131

Li, Y., Hollingworth, P., Moore, P., Foy, C., Archer, N., Powell, J., Nowotny, P., Holmans, Peter Alan, O'Donovan, Michael Conlon, Tacey, K., Doil, L., van Luchene, R., Garcia, V., Rowland, V., Lau, K., Cantanese, J., Sninsky, J., Hardy, J., Thal, L., Morris, J. C., Goate, A., Lovestone, S., Owen, Michael John, Williams, Julie and Grupe, A. 2005. Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease. Human Mutation 25 (3) , pp. 270-277. 10.1002/humu.20138

Cope, N. A., Hill, G., van den Bree, Marianne Bernadette, Harold, D., Escott-Price, Valentina, Green, E. K., Owen, Michael John, Williams, Julie and O'Donovan, Michael Conlon 2005. No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia. Molecular Psychiatry 10 (3) , pp. 237-238. 10.1038/sj.mp.4001596

Cook, L. J., Ho, L. W., Wang, L., Terrenoire, E., Brayne, C., Evans, J. G., Xuereb, J., Cairns, N. J., Turic, D., Hollingworth, P., Moore, P. J., Jehu, L., Archer, N., Walter, S., Foy, C., Edmonson, A., Powell, J., Lovestone, S., Williams, Julie and Rubinsztein, D. C. 2005. Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 132B (1) , pp. 5-8. 10.1002/ajmg.b.30068

Li, Yonghong, Nowotny, Petra, Holmans, Peter Alan, Smemo, Scott, Kauwe, John S. K., Hinrichs, Anthony L., Tacey, Kristina, Doil, Lisa, Luchene, Ryan van, Garcia, Veronica, Rowland, Charles, Schrodi, Steve, Leong, Diane, Gogic, Goran, Chan, Joanne, Cravchik, Anibal, Ross, David, Lau, Kit, Kwok, Shirley, Chang, Sheng-Yung, Catanese, Joseph, Sninsky, John, White, Thomas J., Hardy, John, Powell, John, Lovestone, Simon, Morris, John C., Thal, Leon, Owen, Michael John, Williams, Julie, Goate, Alison and Grupe, Andrew 2004. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proceedings of the National Academy of Sciences 101 (44) , pp. 15688-15693. 10.1073/pnas.0403535101

Bray, Nicholas John, Jehu, Luke, Escott-Price, Valentina, Buckland, Paul Robert, Williams, Julie, Owen, Michael John and O'Donovan, Michael Conlon 2004. Allelic expression of APOE in brain [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B (1) , p. 61.

Bray, Nicholas John, Jehu, Luke, Escott-Price, Valentina, Buckland, Paul Robert, Owen, Michael John, Williams, Julie and O'Donovan, Michael Conlon 2004. P4-101 Allelic expression of APOE in brain [Conference Abstract]. Neurobiology of Aging 25 , S503-S503. 10.1016/S0197-4580(04)81659-2

Cook, Lynnette J., Ho, Luk W., Taylor, Alison E., Brayne, Carol, Evans, John Grimley, Xuereb, John, Cairns, Nigel J., Pritchard, Antonia, Lemmon, Helen, Mann, David, St Clair, David, Turic, Dragana, Hollingworth, Paul, Moore, Pamela J., Jehu, Luke, Archer, Nicola, Walter, Sarah, Foy, Catherine, Edmondson, Amanda, Powell, John, Lovestone, Simon, Owen, Michael John, Williams, Julie, Lendon, Corinne and Rubinsztein, David C. 2004. Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease. Neuroscience Letters 358 (2) , pp. 142-146. 10.1016/j.neulet.2004.01.016

Myers, Amanda J., Marshall, Helen, Holmans, Peter Alan, Compton, Danielle, Crook, Richard J.P., Mander, Adrian P., Nowotny, Petra, Smemo, Scott, Dunstan, Melanie, Jehu, Luke, Wang, Jen C., Hamshere, Marian Lindsay, Morris, John C., Norton, Joanne, Chakraventy, Sumi, Tunstall, Nigel, Lovestone, Simon, Petersen, Ronald, O'Donovan, Michael Conlon, Jones, Lesley, Williams, Julie, Owen, Michael John, Hardy, John and Goate, Alison 2004. Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD. American Journal of Medical Genetics 124B (1) , pp. 29-37. 10.1002/ajmg.b.20036

Busby, Victoria, Goossens, Steven, Nowotny, Petra, Hamilton, Gillian, Smemo, Scott, Harold, Denise, Turic, Dragana, Jehu, Luke, Myers, Amanda, Womick, Meredith, Woo, Daniel, Compton, Danielle, Doil, Lisa M., Tacey, Kristina M., Lau, Kit F., Al-Saraj, Safa, Killick, Richard, Pickering-Brown, Stuart, Moore, Pamela, Hollingworth, Paul, Archer, Nicola, Foy, Catherine, Walter, Sarah, Lovestone, Simon, O'Donovan, Michael Conlon, Owen, Michael John, Jones, Lesley, Williams, Julie and Holmans, Peter Alan 2004. Alpha-T-Catenin Is Expressed in Human Brain and Interacts With the Wnt Signaling Pathway But Is Not Responsible for Linkage to Chromosome 10 in Alzheimer's Disease. Neuromolecular Medicine 5 (2) , pp. 133-146. 10.1385/NMM:5:2:133

Bray, Nicholas John, Jehu, Luke, Moskvina, Vanentina, Buxbaum, Joseph D., Dracheva, Stella, Haroutunian, Vahram, Williams, Julie, Buckland, Paul Robert, Owen, Michael John and O'Donovan, Michael Conlon 2004. Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes. Human Molecular Genetics 13 (22) , pp. 2885-2892. 10.1093/hmg/ddh299

Harold, Denise, Peirce, Timothy, Escott-Price, Valentina, Lovestone, Simon, Powell, John, Foy, Catherine, Archer, Nicola, Walter, Sarah, Edmonson, Amanda, McIlroy, Stephen, Craig, David, Passmore, Peter A., Goate, Alison, Hardy, John, O'Donovan, Michael Conlon, Williams, Julie, Liddell, Malcolm, Owen, Michael John, Jones, Lesley, Myers, Amanda, Jones, Susan, Hollingworth, Paul and Moore, Pamela 2003. Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease. Human Genetics 113 (3) , pp. 258-267. 10.1007/s00439-003-0960-2

Rice, Frances, Abraham, Richard, Rudrasingham, Varuni, Owen, Michael John and Williams, Julie 2003. Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note. International Journal of Geriatric Psychiatry 18 (2) , pp. 155-160. 10.1002/gps.808

Turic, D, Robinson, L, Duke, M, Morris, D W, Webb, V, Hamshere, Marian Lindsay, Milham, C, Hopkin, E, Pound, K, Fernando, S, Grierson, A, Easton, M, Williams, Nigel Melville, van den Bree, Marianne Bernadette, Chowdhury, R, Gruen, J, Stevenson, J, Krawczak, M, Owen, Michael John, O'Donovan, Michael Conlon and Williams, Julie 2003. Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22. Molecular Psychiatry 8 (2) , pp. 176-185. 10.1038/sj.mp.4001216

Heron, J., Jones, Ian Richard, Williams, Julie, Owen, Michael John, Craddock, Nicholas John and Jones, L. 2003. Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire. Schizophrenia Research 65 (2-3) , pp. 153-158. 10.1016/S0920-9964(03)00004-5

Walter, S., Archer, N., Foy, C., Lovestone, Simon, Davis, G., Hollingsworth, P., Jones, S., Moore, P., Owen, Michael John and Williams, Julie 2002. The retained ability to display affection and emotion in Alzheimer's disease. Neurobiology of Aging 23 (1) , S44-S45.

Archer, N., Foy, C., Walter, S., Lovestone, Simon, Davis, G., Hollingworth, Paul, Jones, S., Moore, P, Owen, Michael John and Williams, Julie 2002. Delusions in dementia - An investigation into their persistence and predictive value. Neurobiology of Aging 23 (1) , S156-S156.

Myers, Amanda, Wavrant De-Vrieze, Fabienne, Holmans, Peter Alan, Hamshere, Marian Lindsay, Crook, Richard, Compton, Danielle, Marshall, Helen, Meyer, David, Shears, Shantia, Booth, Jeremy, Ramic, Dzanan, Knowles, Heather, Morris, John C., Williams, Nigel Melville, Norton, Nadine, Abraham, Richard, Kehoe, Pat, Williams, Hywel, Rudrasingham, Varuni, Rice, Frances, Giles, Peter, Tunstall, Nigel, Jones, Lesley, Lovestone, Simon, Williams, Julie, Owen, Michael John, Hardy, John and Goate, Alison 2002. Full genome screen for Alzheimer disease: Stage II analysis. American Journal Of Medical Genetics Part A 114 (2) , pp. 235-244. 10.1002/ajmg.10183

Abraham, Richard, Myers, Amanda, Wavrant-DeVrieze, Fabienne, Hamshere, Marian Lindsay, Thomas, Hollie Victoria, Marshall, Helen, Compton, Danielle, Spurlock, Gillian, Turic, Dragana, Hoogendoorn, Bastiaan, Kwon, Jennifer M., Petersen, Ronald C., Tangalos, Eric, Norton, Joanne, Morris, John C., Bullock, Roger, Liolitsa, Danae, Lovestone, Simon, Hardy, John, Goate, Alison, O'Donovan, Michael Conlon, Williams, Julie, Owen, Michael John and Jones, Lesley 2001. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Human Genetics 109 (6) , pp. 646-652. 10.1007/s00439-001-0614-1

Jones, L. A., Cardno, A. G., Sanders, R. D., Owen, Michael John and Williams, Julie 2001. Sustained and selective attention as measures of genetic liability to schizophrenia. Schizophrenia Research 48 (2-3) , pp. 263-267.

Myers, A., Holmans, Peter Alan, Marshall, H., Kwon, J., Meyer, D., Ramic, D., Shears, S., Booth, J., DeVrieze, F. W., Crook, R., Hamshere, Marian Lindsay, Abraham, R., Tunstall, N., Rice, Frances, Carty, S., Lillystone, S., Kehoe, P., Rudrasingham, V., Jones, Lesley, Lovestone, S., Perez-Tur, J., Williams, Julie, Owen, Michael John, Hardy, J. and Goate, A. M. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290 (5500) , pp. 2304-2305. 10.1126/science.290.5500.2304

Deb, S., Williams, Julie and Owen, Michael John 2000. Apolipoprotein E, Alzheimer's disease and Down's syndrome - Reply. British Journal of Psychiatry 177 , pp. 469-470.

Jones, L. A., Cardno, A. G., Murphy, K. C., Sanders, R. D., Gray, M. Y., McCarthy, G., McGuffin, P., Owen, Michael John and Williams, Julie 2000. The kings schizotypy questionnaire as a quantitative measure of schizophrenia liability. Schizophrenia Research 45 (3) , pp. 213-221. 10.1016/S0920-9964(99)00183-8

Kington, J. M., Jones, L. A., Watt, A. A., Hopkin, E. J. and Williams, Julie 2000. Impaired eye expression recognition in schizophrenia. Journal of Psychiatric Research 34 (4-5) , pp. 341-347.

Deb, S., Braganza, J., Norton, N., Williams, H., Kehoe, P. G., Williams, Julie and Owen, Michael John 2000. APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome. British Journal of Psychiatry 176 , pp. 468-472. 10.1192/bjp.176.5.468

Morris, D. W., Robinson, L., Turic, D., Duke, M., Webb, V., Milham, C., Hopkin, E., Pound, K., Fernando, S., Easton, M., Hamshere, Marian Lindsay, Williams, Nigel Melville, McGuffin, P., Stephenson, Jessica, Krawczak, M., Owen, Michael John, O'Donovan, Michael and Williams, Julie 2000. Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q. Human Molecular Genetics 9 (5) , pp. 843-848. 10.1093/hmg/9.5.843

Tunstall, N., Owen, Michael John, Williams, Julie, Rice, Frances, Carty, S., Lillystone, S., Fraser, L., Kehoe, P., Neill, D., Rudrasingham, V., Sham, P. and Lovestone, S. 2000. Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. British Journal of Psychiatry 176 , pp. 156-159. 10.1192/bjp.176.2.156

Deb, S., Braganza, J., Norton, N., Williams, H., Kehoe, P. G., Williams, Julie and Owen, Michael John 2000. Presence of the Apolipoprotein E e4 allele is associated with the manifestation of Alzheimer dementia in adults with Down syndrome. Journal of Intellectual Disability Research 44 , p. 259.

Jones, L. A., Sanders, R. D., Cardno, A. G., Owen, Michael John and Williams, Julie 1999. Sustained and selective attention as quantitative measures of schizophrenia liability. Molecular Psychiatry 4 , S117-S117.

Sanders, R. D., Norton, Nadine, Williams, Julie and Owen, Michael John 1999. Pre-pulse inhibition in the functional psychoses. Molecular Psychiatry 4 , S121-S121.

Wavrant-De Vrieze, F., Crook, R., Holmans, Peter Alan, Kehoe, P., Owen, Michael John, Williams, Julie, Roehl, K., Laliiri, D. K., Shears, S., Booth, J., Wu, W., Goate, A., Chartier-Harlin, M. C., Hardy, J. and Perez-Tur, J. 1999. Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease. Neuroscience Letters 269 (2) , pp. 67-70.

Williams, Julie, Kehoe, P. G. and Owen, Michael John 1999. Case-control study of presenelin-1 intronic polymorphism. Journal of Neurology, Neurosurgery & Psychiatry 66 (6) , p. 702. 10.1136/jnnp.66.6.702

Wavrant-DeVrieze, F., Rudrasingham, V., Lambert, J. C., Chakraverty, S., Kehoe, P., Crook, R., Amouyel, P., Wu, W., Holmans, Peter Alan, Rice, Frances, Perez-Tur, J., Frigard, B., Morric, J. C., Carty, S., Cottel, D., Tunstall, N., Lovestone, S., Petersen, R. C., Chartier-Harlin, M. C., Goate, A., Owen, Michael John, Williams, Julie and Hardy, J. 1999. No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease. Neuroscience Letters 262 (2) , pp. 137-139. 10.1016/S0304-3940(99)00035-X

Kehoe, P., Wavrant-De Vrieze, F., Crook, R., Wu, W. S., Holmans, Peter Alan, Fenton, I., Williams, Nigel Melville, Lovestone, S., Perez-Tur, J., Hutton, M., Chartier-Harlin, M. C., Shears, S., Roehl, K., Booth, J., Van Voorst, W., Ramic, D., Williams, Julie, Goate, A., Hardy, J. and Owen, Michael John 1999. A full genome scan for late onset Alzheimer's disease. Human Molecular Genetics 8 (2) , pp. 237-245. 10.1093/hmg/8.2.237

Kehoe, P. G., Russ, C., McIlory, S., Williams, H., Powell, J., McGleenon, B., Liddell, M., Plomin, R., Dynan, K., Williams, Nigel Melville, Neal, J., Cairns, N. J., Wilcock, G., Passmore, P., Lovestone, S., Williams, Julie and Owen, Michael John 1999. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nature Genetics 21 (1) , pp. 71-72. 10.1038/5009

Wu, W. S., Holmans, Peter Alan, Wavrant-DeVrieze, F., Shears, S., Kehoe, P., Crook, R., Booth, J., Williams, Nigel Melville, Perez-Tur, J., Roehl, K., Fenton, I., Chartier-Harlin, M. C., Lovestone, S., Williams, Julie, Hutton, M., Hardy, J., Owen, Michael John and Goate, A. 1998. Genetic studies on chromosome 12 in late-onset Alzheimer disease. JAMA - The Journal of the American Medical Association 280 (7) , pp. 619-622. 10.1001/jama.280.7.619

Bowen, Timothy, Guy, Carol, Craddock, Nicholas John, Cardno, A. G., Williams, Nigel Melville, Spurlock, G., Murphy, K. C., Jones, L. A., Gray, M., Sanders, Rebecca, McCarthy, G, Chandy, K. G., Fantino, E, Kalman, K, Gutman, G. A., Gargus, J. J., Williams, Julie, McGuffin, P., Owen, Michael John and O'Donovan, Michael Conlon 1998. Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia. Molecular Psychiatry 3 (3) , pp. 266-269. 10.1038/sj.mp.4000400

Williams, Julie, Spurlock, G., Holmans, Peter Alan, Mant, R., Murphy, K., Jones, L., Cardno, A., Asherson, P., Blackwood, D., Muir, W., Meszaros, K., Aschauer, H., Mallet, J., Laurent, C., Pekkarinen, P., Seppala, J., Stefanis, C. N., Papadimitriou, G. N., Macciardi, F., Verga, M., Pato, C., Azevedo, H., Crocq, M. A., Gurling, H. and Owen, Michael John 1998. A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia. Molecular Psychiatry 3 (2) , pp. 141-149.

Spurlock, G., Williams, Julie, McGuffin, P., Aschauer, H. N., Lenzinger, E., Fuchs, K., Sieghart, W. C., Meszaros, K., Fathi, N., Laurent, C., Mallet, J., Macciardi, F., Pedrini, S., Gill, M., Hawi, Z., Gibson, S., Jazin, E. E., Yang, H. T., Adolfsson, R., Pato, C. N., Dourado, A. M. and Owen, Michael John 1998. European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms. American Journal of Medical Genetics 81 (1) , pp. 24-28. 10.1002/(SICI)1096-8628(19980207)81:1<24::AID-AJMG5>3.0.CO;2-N

Williams, Julie, McGuffin, P., Nothen, . and Owen, Michael John 1997. A meta analysis of association between the 5-HT2a receptor, T102C polymorphism and schizophrenia. American Journal of Medical Genetics 74 (6) , p. 612.

Williams, Julie, McGuffin, Peter, Nothen, Markus and Owen, Michael John 1997. Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia. The Lancet 349 (9060) , p. 1221. 10.1016/S0140-6736(05)62413-0

Spurlock, Gillian, Williams, Julie, McGuffin, Peter, Mallet, Jacques, Nöthen, Markus, Gill, Michael, Aschauer, Harald, Adlfsson, Rolf, Macciardi, Fabio and Owen, Michael John 1997. Meta-analysis of association studies between schizophrenia and polymorphisms of the 5-hydroxytryptamine type 2A receptor gene. Schizophrenia Research 24 (1-2) , p. 91. 10.1016/S0920-9964(97)82247-5

Williams, Nigel Melville, Jones, L. A., Murphy, K. C., Cardno, A. G., Asherson, P., Williams, Julie, McGuffin, P. and Owen, Michael John 1997. No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283. American Journal of Medical Genetics 74 (1) , pp. 37-39. 10.1002/(SICI)1096-8628(19970221)74:1<37::AID-AJMG8>3.0.CO;2-S

Cardno, A. G., Jones, L. A., Murphy, K. C., Asherson, P., Scott, L. C., Williams, Julie, Owen, Michael John and McGuffin, P. 1996. Factor analysis of schizophrenic symptoms using the OPCRIT checklist. Schizophrenia Research 22 (3) , pp. 233-239. 10.1016/S0920-9964(96)00060-6

O'Donovan, Michael Conlon, Guy, Carol, Craddock, Nicholas John, Bowen, Timothy, McKeon, P., Macedo, A., Maier, W., Wildenauer, D., Aschauer, H. N., Sorbi, S., Feldman, E., Mynett-Johnson, L., Claffey, E., Nacmias, B., Valente, J., Dourado, A., Grassi, E., Lenzinger, E., Heiden, A. M., Moorhead, S., Harrison, D., Williams, Julie, McGuffin, P. and Owen, Michael John 1996. Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychological Medicine -London- 26 (6) , pp. 1145-1153. 10.1017/s0033291700035868

Kehoe, P., Williams, Julie, Holmans, Peter Alan, Liddell, M., Lovestone, S., Holmes, C., Powell, J., Neal, J., Wilcock, G. and Owen, Michael John 1996. Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease. NeuroReport 7 (13) , pp. 2155-2158. 10.1097/00001756-199609020-00019

Owen, Michael John, Kehoe, P. and Williams, Julie 1996. Presenilin-1 polymorphism and Alzheimer's disease. The Lancet 348 (9024) , p. 414. 10.1016/S0140-6736(05)65041-6

Williams, Julie, Farmer, A. E., Ackenheil, M., Kaufmann, C. A. and McGuffin, P. 1996. A multicentre inter-rater reliability study using the OPCRIT computerized diagnostic system. Psychological Medicine 26 (4) , pp. 775-783. 10.1017/S003329170003779X

Williams, Julie, Spurlock, G., McGuffin, P., Mallet, J., Nothen, M. M., Gill, M., Aschauer, H., Nylander, P. O., Macciardi, F. and Owen, Michael John 1996. Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group. The Lancet 347 (9011) , pp. 1294-1296. 10.1016/S0140-6736(96)90939-3

Asherson, P., Mant, R., Holmans, Peter Alan, Williams, Julie, Cardno, A., Murphy, K., Jones, L., Collier, D., McGuffin, P. and Owen, Michael John 1996. Linkage, association and mutational analysis of the dopamine D3 receptor gene in schizophrenia. Molecular Psychiatry 1 (2) , pp. 125-132.

Kehoe, P., Williams, Julie, Lovestone, S., Wilcock, G. and Owen, Michael John 1996. Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group. The Lancet 347 (9009) , p. 1185.

Daniels, J. K., Williams, Nigel Melville, Williams, Julie, Jones, L. A., Cardno, A. G., Murphy, K. C., Spurlock, G., Riley, B., Scambler, P., Asherson, P., McGuffin, P. and Owen, Michael John 1996. No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity. American Journal of Psychiatry 153 (2) , pp. 268-270. 10.1176/ajp.153.2.268

Daniels, J., Williams, Julie, Asherson, P, McGuffin, P. and Owen, Michael John 1995. No association between schizophrenia and polymorphisms within the genes for debrisoquine 4-hydroxylase (CYP2D6) and the dopamine transporter (DAT). American Journal of Medical Genetics 60 (1) , pp. 85-87. 10.1002/ajmg.1320600115

Farmer, A. E., Williams, Julie and Jones, Ian Richard 1994. Phenotypic definitions of psychotic illness for molecular genetic research. American Journal of Medical Genetics 54 (4) , pp. 365-371. 10.1002/ajmg.1320540416

Daniels, J., Williams, Julie, Mant, R., Asherson, P., McGuffin, P. and Owen, Michael John 1994. Repeat length variation in the dopamine D4 receptor gene shows no evidence of association with schizophrenia. American Journal of Medical Genetics 54 (3) , pp. 256-258. 10.1002/ajmg.1320540313

Liddell, Malcolm Brandon, Williams, Julie, Bayer, Antony James, Kaiser, F. and Owen, Michael John 1994. Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease. Journal of Medical Genetics 31 (3) , pp. 197-200. 10.1136/jmg.31.3.197

Williams, Julie, Farmer, Anne E., Wessely, Simon, Castle, David J. and McGuffin, Peter 1993. Heterogeneity in schizophrenia: An extended replication of the hebephrenic-like and paranoid-like subtypes. Psychiatry Research 49 (3) , pp. 199-210. 10.1016/0165-1781(93)90061-K

Farmer, Anne E. and Williams, Julie 1993. Defining the phenotype for molecular-genetic research into psychotic illness - problems and solutions. Behavior Genetics 23 (6) , p. 551.

Mant, R., Williams, Julie, Asherson, P., Parfitt, E., McGuffin, P. and Owen, Michael John 1993. Susceptibility to schizophrenia and the dopamine d3 receptor gene. American Journal of Human Genetics 53 (3) , p. 1654.

Crocq, M A, Mant, R, Asherson, P, Williams, Julie, Hode, Y, Mayerova, A, Collier, D, Lannfelt, L, Sokoloff, P and Schwartz, J C 1992. Association between schizophrenia and homozygosity at the dopamine D3 receptor gene. Journal of Medical Genetics 29 (12) , pp. 858-860. 10.1136/jmg.29.12.858

Owen, Michael John, Mant, R., Parfitt, E., Williams, Julie, Asherson, P., O'Mahoney, G., Van Os, J., Llewellyn, D., Collier, D., Gill, M. and McGuffin, P. 1992. No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia. Human Genetics 90 (1-2) , pp. 131-132. 10.1007/BF00210756