ORCA
Online Research @ CardiffÂ
Browse by Current Cardiff authors
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Number of items: 14.
Young, Madeleine, May, Stephanie, Damo, Angelos, Young, So Yoon, Man-Wook, Hur, Wojiech, Swat and Parry, Lee
2019.
Epigenetic regulation of Dlg1, via Kaiso, alters mitotic spindle polarity and promotes intestinal tumourigenesis.
Molecular Cancer Research
17
(3)
, pp. 686-696.
10.1158/1541-7786.MCR-18-0280
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| Young, Madeleine, Daly, Carl, Taylor, Elaine, James, Rhiannon, Clarke, Alan and Reed, Karen 2018. Subtle deregulation of the Wnt-signalling pathway through loss of Apc2 reduces the fitness of intestinal stem cells. Stem Cells 36 (1) , pp. 114-122. 10.1002/stem.2712 |
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Young, Madeleine and Reed, Karen Ruth
2016.
Organoids as a model for colorectal cancer.
Current Colorectal Cancer Reports
12
(5)
, pp. 281-287.
10.1007/s11888-016-0335-4
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| Reed, Karen Ruth, Song, Fei, Young, Madeleine, Hassan, N., Antoine, A. J., Gemici, Nesibe-Princess B, Clarke, Alan Richard and Jenkins, J. R. 2016. Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. Oncotarget 7 (32) , pp. 51665-51673. 10.18632/oncotarget.10076 |
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| Parry, Lee, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard 2015. Protocols for analyzing the role of Paneth cells in regenerating the murine intestine using conditional cre-lox mouse models. Journal of Visualized Experiments (105) , e53429. 10.3791/53429 |
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| Meniel, Valerie, Megges, M., Young, Madeleine, Cole, A., Sansom, O. J. and Clarke, Alan Richard 2015. Apc and p53 interaction in DNA damage and genomic instability in hepatocytes. Oncogene 34 , pp. 4118-4129. 10.1038/onc.2014.342 |
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| Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint Trefor, Metzger, Daniel, Shorning, Boris and Clarke, Alan Richard 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453 |
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| Holik, Aliaksei, Krzystyniak, Joanna, Young, Madeleine, Richardson, Kirsty, Jarde, Thierry, Chambon, Pierre, Shorning, Boris and Clarke, Alan Richard 2013. Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner. Stem Cells 31 (11) , pp. 2457-2466. 10.1002/stem.1498 |
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| Parry, Lee, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard 2013. Evidence for a crucial role of Paneth Cells in mediating the intestinal response to injury. Stem Cells 31 (4) , pp. 776-785. 10.1002/stem.1326 |
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| Young, Madeleine, Ordonez, Liliana and Clarke, Alan Richard 2013. What are the best routes to effectively model human colorectal cancer? Molecular Oncology 7 (2) , pp. 178-189. 10.1016/j.molonc.2013.02.006 |
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| Meniel, Valerie, Song, Fei, Phesse, Toby, Young, Madeleine, Poetz, Oliver, Parry, Lee, Jenkins, John R., Williams, Geraint Trefor, Dunwoodie, Sally L., Watson, Alastair and Clarke, Alan Richard 2013. Cited1 deficiency suppresses intestinal tumorigenesis. PLoS Genetics 9 (8) , e1003638. 10.1371/journal.pgen.1003638 |
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Young, Madeleine
2013.
The effects of aberrant Wnt signalling on the murine intestinal stem cell compartment.
PhD Thesis,
Cardiff University.
Item availability restricted. |
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| Reed, Karen Ruth, Tunster, Simon James, Young, Madeleine, Carrico, Adam Stephen, John, Rosalind Margaret and Clarke, Alan Richard 2012. Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice. Gut 61 (10) , pp. 1435-1438. 10.1136/gutjnl-2011-300842 |
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| Young, Madeleine and Clarke, Alan Richard 2011. Expanding the p53 toolkit: A new platform for rapid engineering of the p53 locus in vivo [Note]. Cell Cycle 10 (14) , p. 2249. 10.4161/cc.10.14.16205 |
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