Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Current Cardiff authors

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Number of items: 148.

Morgan, Bryan Paul 2017. Complement in the pathogenesis of Alzheimer's disease. Seminars in Immunopathology 10.1007/s00281-017-0662-9
file

Morgan, Angharad, O'Hagan, Caroline, Touchard, Samuel, Lovestone, Simon and Morgan, Bryan Paul 2017. Effects of freezer storage time on levels of complement biomarkers. BMC Research Notes 10 (1) , 559. 10.1186/s13104-017-2885-1
file

Taylor, Ronald P., Lindorfer, Margaret A., Cook, Erika M., Beurskens, Frank J., Schuurman, Janine, Parren, Paul W.H.I., Zent, Clive S., VanDerMeid, Karl R., Burack, Richard, Mizuno, Masashi and Morgan, B. Paul 2017. Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9. Clinical Immunology 181 , pp. 24-28. 10.1016/j.clim.2017.05.016
file

Loveless, Samantha, Neal, James W., Howell, Owain W., Harding, Katherine, Sarkies, Patrick, Evans, Rhian, Bevan, Ryan J, Hakobyan, Svetlana, Harris, Claire, Robertson, Neil and Morgan, Bryan Paul 2017. Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis. Brain Pathology
Item availability restricted.
file

Morgan, Bryan Paul, Boyd, Courtney and Bubeck, Doryen 2017. Molecular cell biology of complement membrane attack. Seminars in Cell and Developmental Biology
Item availability restricted.
file

Hakobyan, Svetlana, Luppe, Sebastian, Evans, David R. S., Harding, Katharine, Loveless, Samantha, Robertson, Neil P. and Morgan, Bryan Paul 2017. Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder. Multiple Sclerosis Journal 23 (7) , pp. 946-955. 10.1177/1352458516669002
file

Granados-Durán, Pablo, López-Ávalos, María Dolores, Cifuentes, Manuel, Pérez-Martín, Margarita, Fernández-Arjona, María del Mar, Hughes, Timothy, Johnson, Krista, Morgan, Bryan, Fernández-Llebrez, Pedro and Grondona, Jesús M. 2017. Microbial neuraminidase induces a moderate and transient myelin vacuolation independent of complement system activation. Frontiers in Neurology 8 10.3389/fneur.2017.00078
file

Morgan, Angharad, Touchard, Samuel, O'Hagan, Caroline, Sims, Rebecca, Majounie, Elisa, Escott-Price, Valentina, Jones, Lesley, Williams, Julie and Morgan, Bryan 2017. The correlation between inflammatory biomarkers and polygenic risk score in Alzheimer's Disease. Journal of Alzheimer's Disease 56 (1) , pp. 25-36. 10.3233/JAD-160889
file

Stover, Cordula M., Mizuno, Masashi, Suzuki, Yasuhiro, Higashide, Keiko, Sei, Yumi, Iguchi, Daiki, Sakata, Fumiko, Horie, Masanobu, Maruyama, Shoichi, Matsuo, Seiichi, Morgan, Bryan and Ito, Yasuhiko 2017. High levels of soluble C5b-9 complex in dialysis fluid may predict poor prognosis in peritonitis in peritoneal dialysis patients. PLoS ONE 12 (1) , e0169111. 10.1371/journal.pone.0169111
file

Granados-Duran, Pablo, Lopez-Avalos, Maria Dolores, Hughes, Timothy Richard, Johnson, Krista, Morgan, Bryan Paul, Tamburini, Paul P., Fernandez-Llebrez, Pedro and Grondona, Jesus M. 2016. Complement system activation contributes to the ependymal damage induced by microbial neuraminidase. Journal of Neuroinflammation 13 (115) 10.1186/s12974-016-0576-9
file

Morgan, Bryan Paul, Walters, David, Serna, Marina and Bubeck, Doryen 2016. Terminal complexes of the complement system: new structural insights and their relevance to function. Immunological Reviews 274 (1) , pp. 141-151. 10.1111/imr.12461

Hakobyan, Svetlana, Harding, Katharine, Aiyaz, Mohammed, Hye, Abdul, Dobson, Richard, Baird, Alison, Liu, Benjamine, Harris, Claire, Lovestone, Simon and Morgan, Bryan 2016. Complement biomarkers as predictors of disease progression in Alzheimer's disease. Journal of Alzheimer's Disease 54 (2) , pp. 707-716. 10.3233/JAD-160420
file

Heurich-Sevcenco, Meike, Preston, R.J.S., O'Donnell, Valerie Bridget, Morgan, Bryan Paul and Collins, Peter William 2016. Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex. Thrombosis Research 145 , pp. 84-92. 10.1016/j.thromres.2016.07.017
file

Towner, Laurence D., Wheat, Richard, Hughes, Timothy and Morgan, Bryan Paul 2016. Complement membrane attack and tumorigenesis: a systems biology approach. Journal of Biological Chemistry 291 (29) , pp. 14927-14938. 10.1074/jbc.M115.708446
file

Watkins, Lewis M., Neal, James W., Loveless, Samantha, Michailidou, Iliana, Ramaglia, Valeria, Rees, Mark I., Reynolds, Richard, Robertson, Neil, Morgan, Bryan Paul and Howell, Owain W. 2016. Complement is activated in progressive multiple sclerosis cortical grey matter lesions. Journal of Neuroinflammation 13 , 161. 10.1186/s12974-016-0611-x
file

Morgan, Bryan Paul 2016. The membrane attack complex as an inflammatory trigger. Immunobiology 221 (6) , pp. 747-751. 10.1016/j.imbio.2015.04.006

Williams, Pete A., Tribble, James R., Pepper, Keating W., Cross, Stephen D., Morgan, Bryan Paul, Morgan, James E., John, Simon W. M. and Howell, Gareth R. 2016. Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma. Molecular Neurodegeneration 11 , 26. 10.1186/s13024-016-0091-6
file

Bloom, Anja C., Collins, Fraser L., van't Hof, Rob J., Ryan, Elizabeth S., Jones, Emma, Hughes, Timothy Richard, Morgan, Bryan Paul, Erlandsson, Malin, Bokarewa, Maria, Aeschlimann, Daniel, Evans, Bronwen Alice James and Williams, Anwen Sian 2016. Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice. Bone 84 , pp. 253-261. 10.1016/j.bone.2015.12.014
file

Szarvas, Nóra, Szilágyi, Ágnes, Csuka, Dorottya, Takács, Beáta, Rusai, Krisztina, Müller, Thomas, Arbeiter, Klaus, Réti, Marienn, Haris, Ágnes, Wagner, László, Török, Szilárd, Kelen, Kata, Szabó, Attila J., Reusz, György S., Morgan, Bryan Paul and Prohászka, Zoltán 2016. Genetic analysis and functional characterization of novel mutations in a series of patients with atypical hemolytic uremic syndrome. Molecular Immunology 71 , pp. 10-22. 10.1016/j.molimm.2016.01.003

Serna, Marina, Giles, Joanna L., Morgan, Bryan Paul and Bubeck, Doryen 2016. Structural basis of complement membrane attack complex formation. Nature Communications 7 , 10587. 10.1038/ncomms10587
file

Triantafilou, Martha, Hughes, Timothy, Morgan, Bryan and Triantafilou, Kathy 2016. Complementing the inflammasome. Immunology 147 (2) , pp. 152-164. 10.1111/imm.12556

Bahia El Idrissi, N., Hakobyan, S., Ramaglia, V., Geluk, A., Morgan, Bryan Paul, Das, P. Kumar and Baas, F. 2016. Complement activation in leprosy: a retrospective study shows elevated circulating terminal complement complex in reactional leprosy. Clinical and Experimental Immunology 184 (3) , p. 338. 10.1111/cei.12767

Ruseva, Marieta Milkova, Ramaglia, Valeria, Morgan, Bryan Paul and Harris, Claire Louise 2015. An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice. Proceedings of the National Academy of Sciences 112 (46) , pp. 14319-14324. 10.1073/pnas.1513698112
file

Mook-Kanamori, B. B., Valls Serón, M., Geldhoff, M., Havik, S. R., van der Ende, A., Baas, F., van der Poll, T., Meijers, J. C. M., Morgan, Bryan Paul, Brouwer, M. C. and van de Beek, D. 2015. Thrombin-activatable fibrinolysis inhibitor influences disease severity in humans and mice with pneumococcal meningitis. Journal of Thrombosis and Haemostatis 13 (11) , pp. 2076-2086. 10.1111/jth.13132

Morgan, Bryan 2015. The role of complement in neurological and neuropsychiatric diseases. Expert Review of Clinical Immunology 11 (10) , pp. 1109-1119. 10.1586/1744666X.2015.1074039

Ramaglia, V., Jackson, S. J., Hughes, Timothy, Neal, James, Baker, D. and Morgan, Bryan 2015. Complement activation and expression during chronic relapsing experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Clinical & Experimental Immunology 180 (3) , pp. 432-441. 10.1111/cei.12595

Bahia El Idrissi, Nawal, Das, Pranab K., Fluiter, Kees, Rosa, Patricia S., Vreijling, Jeroen, Troost, Dirk, Morgan, Bryan, Baas, Frank and Ramaglia, Valeria 2015. M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator. Acta Neuropathologica 129 (5) , pp. 653-667. 10.1007/s00401-015-1404-5

Owen, E. Patricia, Würzner, Reinhard, Leisegang, Felicity, Rizkallah, Pierre, Whitelaw, Andrew, Simpson, John, Thomas, Andrew David, Harris, Claire Louise, Giles, Joanna L., Hellerud, Bernt C., Mollnes, Tom E., Morgan, Bryan Paul, Potter, Paul C. and Orren, Ann 2015. A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases. Molecular Immunology 64 (1) , pp. 170-176. 10.1016/j.molimm.2014.11.010

Giles, Joanna, Choy, Ernest Ho Sing, Van Den Berg, Carmen, Morgan, Bryan Paul and Harris, Claire Louise 2015. Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis. The Journal of Immunology 194 (7) , pp. 3029-3034. 10.4049/jimmunol.1402956
file

Martínez-Barricarte, Rubén, Heurich-Sevcenco, Meike, López-Perrote, Andrés, Tortajada, Agustin, Pinto, Sheila, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, Bryan Paul, Llorca, Oscar, Harris, Claire Louise and Rodríguez de Córdoba, Santiago 2015. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. Molecular Immunology 66 (2) , pp. 263-273. 10.1016/j.molimm.2015.03.248
file

Challis, R. C., Araujo, G. S. R., Wong, E. K. S., Anderson, H. E., Awan, A., Dorman, A. M., Waldron, M., Wilson, V., Brocklebank, V., Strain, L., Morgan, Bryan, Harris, Claire, Marchbank, K. J., Goodship, T. H. J. and Kavanagh, D. 2015. A de novo deletion in the regulators of complement activation cluster producing a hybrid complement factor H/complement factor H-related 3 gene in atypical hemolytic uremic syndrome. Journal of the American Society of Nephrology 27 (6) , p. 1617. 10.1681/ASN.2015010100

Subias, Marta, Tortajada, Agustin, Gastoldi, Sara, Galbusera, Miriam, Lopez-Perrote, Andres, Lopez, Lucia de Juana, Gonzalez-Fernandez, Fernando Ataulfo, Villegas-Martinez, Ana, Dominguez, Mercedes, Llorca, Oscar, Noris, Marina, Morgan, Bryan and Rodriguez de Cordoba, Santiago 2014. A novel antibody against human factor B that blocks formation of the C3bB proconvertase and inhibits complement activation in disease models. The Journal of Immunology 193 (11) , pp. 5567-5575. 10.4049/jimmunol.1402013

Clark, Simon J., Schmidt, Christoph Q., White, Anne W., Hakobyan, Svetlana, Morgan, Bryan and Bishop, Paul N. 2014. Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration. The Journal of Immunology 193 (10) , pp. 4962-4970. 10.4049/jimmunol.1401613

Paixao-Cavalcante, Danielle, Torreira, Eva, Lindorfer, Margaret A., Rodriguez de Cordoba, Santiago, Morgan, Bryan, Taylor, Ronald P., Llorca, Oscar and Harris, Claire 2014. A humanized antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors. The Journal of Immunology 192 (10) , pp. 4844-4851. 10.4049/jimmunol.1303131

Ingram, Gillian, Loveless, Samantha, Howell, Owain W., Hakobyan, Svetlana, Dancey, Bethan, Harris, Claire Louise, Robertson, Neil, Neal, James W. and Morgan, Bryan Paul 2014. Complement activation in multiple sclerosis plaques: an immunohistochemical analysis. Acta Neuropathologica Communications 2 (1) , 53. 10.1186/2051-5960-2-53
file

Fluiter, Kees, Opperhuizen, Anne Loes, Morgan, Bryan, Baas, Frank and Ramaglia, Valeria 2014. Inhibition of the membrane attack complex of the complement system reduces secondary neuroaxonal loss and promotes neurologic recovery after traumatic brain injury in mice. The Journal of Immunology 192 (5) , pp. 2339-2348. 10.4049/jimmunol.1302793

Donev, Rossen M., Sivasankar, Baalasubramanian, Mizuno, Masashi and Morgan, Bryan 2014. Retraction notice to "The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility" [Mol. Immunol. 45 (2008) 534?542]. Molecular Immunology 58 (1) , p. 150. 10.1016/j.molimm.2013.12.001

Pickering, Matthew C, D'Agati, Vivette D, Nester, Carla M, Smith, Richard J, Haas, Mark, Appel, Gerald B, Alpers, Charles E, Bajema, Ingeborg M, Bedrosian, Camille, Braun, Michael, Doyle, Mittie, Fakhouri, Fadi, Fervenza, Fernando C, Fogo, Agnes B, Frémeaux-Bacchi, Véronique, Gale, Daniel P, Goicoechea de Jorge, Elena, Griffin, Gene, Harris, Claire Louise, Holers, V Michael, Johnson, Sally, Lavin, Peter J, Medjeral-Thomas, Nicholas, Morgan, Bryan Paul, Nast, Cynthia C, Noel, Laure-Hélène, Peters, D Keith, Rodríguez de Córdoba, Santiago, Servais, Aude, Sethi, Sanjeev, Song, Wen-Chao, Tamburini, Paul, Thurman, Joshua M, Zavros, Michael and Cook, H Terence 2013. C3 glomerulopathy: consensus report. Kidney International 84 (6) , pp. 1079-1089. 10.1038/ki.2013.377

Khandhadia, Samir, Hakobyan, Svetlana, Heng, Ling Z., Gibson, Jane, Adams, David H., Alexander, Graeme J., Gibson, Jonathan M., Martin, Keith R., Menon, Geeta, Nash, Kathryn, Sivaprasad, Sobha, Ennis, Sarah, Cree, Angela J., Morgan, Bryan Paul and Lotery, Andrew J. 2013. Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation. Ophthalmology 120 (8) , pp. 1612-1618. 10.1016/j.ophtha.2013.01.004

Laudisi, F., Spreafico, R., Evrard, M., Hughes, Timothy Richard, Mandriani, B., Kandasamy, M., Morgan, Bryan Paul, Sivasankar, B. and Mortellaro, A. 2013. Cutting edge: The NLRP3 inflammasome links complement-mediated inflammation and IL-1β release. The Journal of Immunology 191 (3) , pp. 1006-1010. 10.4049/jimmunol.1300489
file

Killick, R., Hughes, Timothy Richard, Morgan, Bryan Paul and Lovestone, S. 2013. Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99] [Corrigendum]. Neuroscience Letters 545 , p. 144. 10.1016/j.neulet.2013.05.004

Goicoechea de Jorge, E., Caesar, J. J. E., Malik, T. H., Patel, M., Colledge, M., Johnson, S., Hakobyan, Svetlana, Morgan, Bryan Paul, Harris, Claire Louise, Pickering, M. C. and Lea, S. M. 2013. Dimerization of complement factor H-related proteins modulates complement activation in vivo. Proceedings of the National Academy of Sciences of the United States of America 110 (12) , pp. 4685-4690. 10.1073/pnas.1219260110

Clark, S. J., Ridge, L. A., Herbert, A. P., Hakobyan, Svetlana, Mulloy, B., Lennon, R., Wurzner, R., Morgan, Bryan Paul, Uhrin, D., Bishop, P. N. and Day, A. J. 2013. Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions. The Journal of Immunology 190 (5) , pp. 2049-2057. 10.4049/jimmunol.1201751

Killick, R., Hughes, Timothy Richard, Morgan, Bryan Paul and Lovestone, S. 2013. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neuroscience Letters 533 , pp. 96-99. 10.1016/j.neulet.2012.11.008

Kandasamy, Matheswaran, Ying, Poon C., Ho, Adrian W. S., Sumatoh, Hermi R., Schlitzer, Andreas, Hughes, Timothy Richard, Kemeny, David M., Morgan, Bryan Paul, Ginhoux, Florent and Sivasankar, Baalasubramanian 2013. Complement mediated signaling on pulmonary CD103+ dendritic cells is critical for their migratory function in response to influenza infection. PLoS Pathogens 9 (1) , e1003115. 10.1371/journal.ppat.1003115
file

Adriani, Kirsten S., Brouwer, Matthijs C., Geldhoff, Madelijn, Baas, Frank, Zwinderman, Aeilko H., Morgan, Bryan Paul, Harris, Claire Louise, van der Ende, Arie and van de Beek, Diederik 2013. Common polymorphisms in the complement system and susceptiblity to bacterial meningitis. Journal of Infection 66 (3) , pp. 255-262. 10.1016/j.jinf.2012.10.008

Paixao Cavalcante, Danielle, López-Trascasa, Margarita, Skattum, Lillemor, Giclas, Patricia C, Goodship, Timothy H, de Córdoba, Santiago Rodríguez, Truedsson, Lennart, Morgan, Bryan Paul and Harris, Claire Louise 2012. Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation. Kidney International 82 (10) , pp. 1084-1092. 10.1038/ki.2012.250
file

Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire Louise, Harris, Claire Louise, Loveless, Samantha, Mitchell, John Paul, Pickersgill, Trevor, Robertson, Neil and Morgan, Bryan Paul 2012. Systemic complement profiling in multiple sclerosis as a biomarker of disease state. Multiple Sclerosis Journal 18 (10) , pp. 1401-1411. 10.1177/1352458512438238
file

Harris, Claire Louise, Heurich, Meike, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul 2012. The complotype: dictating risk for inflammation and infection. Trends in Immunology 33 (10) , pp. 513-521. 10.1016/j.it.2012.06.001

Kempshall, Emma, Thebault, Simon, Morgan, Bryan Paul, Harris, Claire Louise and Gallimore, Awen Myfanwy 2012. Complement-induced protection: an explanation for the limitations of cell-based tumour immunotherapies. Immunology and Cell Biology 90 (9) , pp. 869-871. 10.1038/icb.2012.30

Mizuno, Masashi, Ito, Yasuhiko and Morgan, Bryan Paul 2012. Exploiting the nephrotoxic effects of venom from the sea anemone, phyllodiscus semoni, to create a hemolytic uremic syndrome model in the rat. Marine Drugs 10 (7) , pp. 1582-1604. 10.3390/md10071582
file

Elvington, Michelle, Huang, Yuxiang, Morgan, Bryan Paul, Qiao, Fei, van Rooijen, Nico, Atkinson, Carl and Tomlinson, Stephen 2012. A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood 119 (25) , pp. 6043-6051. 10.1182/blood-2011-10-383232

Mizuno, Masashi, Ito, Yasuhiko, Mizuno, Tomohiro, Harris, Claire Louise, Suzuki, Yasuhiro, Okada, Noriko, Matsuo, Seiichi and Morgan, Bryan Paul 2012. Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats. American Journal of Physiology-Renal Physiology 302 (10) , F1245-F1251. 10.1152/ajprenal.00652.2011

Sacks, Steven and Morgan, Bryan Paul 2012. Complement UK - how and why it started [Editorial]. Immunobiology 217 (2) , pp. 125-126. 10.1016/j.imbio.2011.05.001

Pappworth, Isabel Y., Hayes, Christine, Dimmick, Jason, Morgan, Bryan Paul, Holers, V. Michael and Marchbank, Kevin J. 2012. Mice expressing human CR1/CD35 have an enhanced humoral immune response to T-dependent antigens but fail to correct the effect of premature human CR2 expression. Immunobiology 217 (2) , pp. 147-157. 10.1016/j.imbio.2011.06.001

Ramaglia, Valeria, Hughes, Timothy Richard, Donev, Rossen Mintchev, Ruseva, Marieta Milkova, Wu, Xiaobo, Huitinga, Inge, Baas, Frank, Neal, James William and Morgan, Bryan Paul 2012. C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proceedings of the National Academy of Sciences 109 (3) , pp. 965-970. 10.1073/pnas.1111924109

Gibson, J., Hakobyan, Svetlana, Cree, A. J., Collins, A., Harris, Claire Louise, Ennis, S., Morgan, Bryan Paul and Lotery, A. J. 2012. Variation in complement component C1 inhibitor in age-related macular degeneration. Immunobiology 217 (2) , pp. 251-255. 10.1016/j.imbio.2011.07.015

Thomas, Andrew David, Orren, Ann, Connaughton, J., Feighery, C., Morgan, Bryan Paul and Roberts, Andrew Glyn 2012. Characterization of a large genomic deletion in four Irish families with C7 deficiency. Molecular Immunology 50 (1-2) , pp. 57-59. 10.1016/j.molimm.2011.12.002

Ingram, Gillian, Hakobyan, Svetlana, Loveless, Samantha, Robertson, Neil and Morgan, Bryan Paul 2011. Complement regulator factor H in multiple sclerosis. Journal of Cellular Biochemistry 112 (10) , pp. 2653-2654. 10.1002/jcb.23204

Paringe, Vishal, Bloom, A. C., Choy, Ernest Ho Sing, Morgan, Bryan Paul and Williams, Anwen Sian 2011. Compromised expression of the complement membrane inhibitor CD59a propagates age-related joint degeneration in mice [Poster Abstract]. Arthritis and Rheumatism 63 (s10) , S947-S947. 10.1002/art.33310

Bloom, Anja Constanze, Collins, Fraser, Evans, Bronwen Alice James, Aeschlimann, Daniel P., Morgan, Bryan Paul and Williams, Anwen Sian 2011. CD59 an unexpected protective role in bone [Abstract]. Bone 48 , S161-S162.

Kolev, Martin, Morgan, Bryan Paul, Ruseva, Marieta Milkova and Donev, Rossen Mintchev 2011. Retraction: targeting neural-restrictive silencer factor sensitizes tumor cells to antibody-based cancer immunotherapy in vitro via multiple mechanisms. The Journal of Immunology 187 (12) , p. 6581. 10.4049/jimmunol.1190073

de Córdoba, Santiago Rodríguez, Harris, Claire Louise, Morgan, Bryan Paul and Llorca, Oscar 2011. Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. Biochimica et Biophysica Acta - Molecular Basis of Disease 1812 (1) , pp. 12-22. 10.1016/j.bbadis.2010.09.002

Morgan, Bryan Paul 2011. Therapeutic Agents for Hereditary Angioedema [Letter]. New England Journal of Medicine 364 (1) , p. 86.

Lewis, Ruth D., Perry, Mark J., Guschina, Irina, Jackson, Christopher L., Morgan, Bryan Paul and Hughes, Timothy Richard 2011. CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism. American Journal of Pathology 179 (4) , pp. 1601-1607. 10.1016/j.ajpath.2011.06.015

Heurich, Meike, Martinez-Barricarte, Ruben, Francis, Nigel, Roberts, Dawn L., Rodriguez de Cordoba, Santiago, Morgan, Bryan Paul and Harris, Claire Louise 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108 (21) , pp. 8761-8766. 10.1073/pnas.1019338108

Roversi, P., Johnson, S., Caesar, J. J. E., McLean, F., Leath, K. J., Tsiftsoglou, S. A., Morgan, Bryan Paul, Harris, Claire Louise, Sim, R. B. and Lea, S. M. 2011. Structural basis for complement factor I control and its disease-associated sequence polymorphisms. Proceedings of the National Academy of Sciences of the United States of America 108 (31) , pp. 12839-12844. 10.1073/pnas.1102167108

Bubeck, Doryen, Roversi, Pietro, Donev, Rossen Mintchev, Morgan, Bryan Paul, Llorca, Oscar and Lea, Susan M. 2011. Structure of human complement C8, a precursor to membrane attack. Journal of Molecular Biology 405 (2) , pp. 325-330. 10.1016/j.jmb.2010.10.031

Heurich, Bianca, el Idrissi, Nawal Bahia, Donev, Rossen Mintchev, Petri, Susanne, Claus, Peter, Neal, James, Morgan, Bryan Paul and Ramaglia, Valeria 2011. Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis. Journal of Neuroimmunology 235 (1-2) , pp. 104-109. 10.1016/j.jneuroim.2011.03.011

Woehrl, Bianca, Brouwer, Matthijs C., Murr, Carmen, Heckenberg, Sebastiaan G.B., Baas, Frank, Pfister, Hans W., Zwinderman, Aeilko H., Morgan, Bryan Paul, Barnum, Scott R., Van der Ende, Arie, Koedel, Uwe and van de Beek, Diederik 2011. Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis. Journal of Clinical Investigation 121 (10) , pp. 3943-3953. 10.1172/JCI57522
file

Roversi, Pietro, Johnson, Steven, Caesar, Joseph J. E., McLean, Florence, Leath, Kirstin J., Tsiftsoglou, Stefanos A., Morgan, Bryan Paul, Harris, Claire Louise, Sim, Robert B. and Lea, Susan M. 2011. Structures of the rat complement regulator CrrY. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 67 (7) , pp. 739-743. 10.1107/S1744309111016551

Lueck, K., Wasmuth, S., Williams, J., Hughes, Timothy Richard, Morgan, Bryan Paul, Lommatzsch, A., Greenwood, J., Moss, Sarah E. and Pauleikhoff, D. 2011. Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration. Eye 25 (8) , pp. 1074-1082. 10.1038/eye.2011.109

Raby, Anne-Catherine, Holst, Benjamin, Davies, James Anthony, Colmont, Chantal Sophie, Laumonnier, Yves, Coles, Barbara, Shah, Sanjoy, Hall, Judith Elizabeth, Topley, Nicholas, Köhl, Jörg, Morgan, Bryan Paul and Labeta, Mario Oscar 2011. TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. European Journal of Immunology 41 (9) , pp. 2741-2752. 10.1002/eji.201041350
file

Martínez-Barricarte, Rubén, Heurich, Meike, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, Bryan Paul, Llorca, Oscar, Harris, Claire Louise and Rodríguez de Córdoba, Santiago 2010. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. Journal of Clinical Investigation 120 (10) , pp. 3702-3712. 10.1172/JCI43343
file

Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire Louise, Harris, Claire Louise, Pickersgill, Trevor, Cossburn, Mark D., Loveless, Samantha, Robertson, Neil and Morgan, Bryan Paul 2010. Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. Brain 133 (6) , pp. 1602-1611. 10.1093/brain/awq085

Manickam, Balasubramanian, Jha, Purushottam, Hepburn, Natalie Jayne, Morgan, Bryan Paul, Harris, Claire Louise, Bora, Puran S. and Bora, Nalini S. 2010. Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU). Molecular Immunology 48 (1-3) , pp. 231-239. 10.1016/j.molimm.2010.08.006

Tediose, Teeo, Kolev, Martin Veselinov, Baalasubramanian, Sivasankar, Brennan, Paul, Morgan, Bryan Paul and Donev, Rossen Mintchev 2010. Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation. Nucleic Acids Research 38 (9) , pp. 2799-2812. 10.1093/nar/gkq013

Ingram, Gillian, Hakobyan, Svetlana, Robertson, Neil and Morgan, Bryan Paul 2010. Elevated plasma C4a levels in multiple sclerosis correlate with disease activity. Journal of Neuroimmunology 223 (1-2) , pp. 124-127. 10.1016/j.jneuroim.2010.03.014

Morgan, Bryan Paul 2010. Hereditary Angioedema - Therapies Old and New [Editorial]. New England Journal of Medicine 363 (6) , pp. 581-583. 10.1056/NEJMe1006450

Clark, S. J., Perveen, R., Hakobyan, Svetlana, Morgan, Bryan Paul, Sim, R. B., Bishop, P. N. and Day, A. J. 2010. Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina. Journal of Biological Chemistry 285 (39) , pp. 30192-30202. 10.1074/jbc.M110.103986

Bora, N. S., Jha, P., Lyzogubov, V. V., Kaliappan, S., Liu, J., Tytarenko, R. G., Fraser, Deborah A., Morgan, Bryan Paul and Bora, P. S. 2010. Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice. Journal of Biological Chemistry 285 (44) , pp. 33826-33833. 10.1074/jbc.M110.153130

Lewis, Ruth D., Jackson, Christopher L., Morgan, Bryan Paul and Hughes, Timothy Richard 2010. The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice. Molecular Immunology 47 (5) , pp. 1098-1105. 10.1016/j.molimm.2009.10.035

Johnson, S. A., Williams, J. M., Hakobyan, Svetlana, Richards, A., Perkins, Sarah, Marchbank, K. J., Goodship, T. H. J., Morgan, Bryan Paul, Taylor, Christopher Matthew and Savage, C. O. S. 2010. Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome - A pedigree revisited. Molecular Immunology 47 (7-8) , pp. 1585-1591. 10.1016/j.molimm.2009.12.001

Copland, D. A., Hussain, K., Baalasubramanian, Sivasankar, Hughes, Timothy Richard, Morgan, Bryan Paul, Xu, H., Dick, A. D. and Nicholson, L. B. 2010. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clinical and Experimental Immunology 159 (3) , pp. 303-314. 10.1111/j.1365-2249.2009.04070.x

Mizuno, Tomohiro, Mizuno, Masashi, Morgan, Bryan Paul, Noda, Yukihiro, Yamada, Kiyofumi, Okada, Noriko, Yuzawa, Yukio, Matsuo, Seiichi and Ito, Yasuhiko 2010. Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation. Nephrology Dialysis Transplantation 26 (6) , pp. 1821-1830. 10.1093/ndt/gfq683

Harhausen, Denise, Khojasteh, Uldus, Stahel, Philip F, Morgan, Bryan Paul, Nietfeld, Wilfried, Dirnagl, Ulrich and Trendelenburg, George 2010. Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice. Journal of Neuroinflammation 7 , pp. 15-26. 10.1186/1742-2094-7-15
file

Qiao, Fei, Atkinson, Carl, Kindy, Mark S., Shunmugavel, Anandakumar, Morgan, Bryan Paul, Song, Hongbin and Tomlinson, Stephen 2010. The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. American Journal of Pathology 177 (6) , pp. 3061-3070. 10.2353/ajpath.2010.100158

Ten, Vadim S., Yao, Jun, Ratner, Veniamin, Sosunov, Sergey, Fraser, Deborah A., Botto, Marina, Baalasubramanian, Sivasankar, Morgan, Bryan Paul, Silverstein, Samuel, Stark, Raymond, Polin, Richard, Vannucci, Susan J., Pinsky, David and Starkov, Anatoly A. 2010. Complement component C1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury. Journal of Neuroscience 30 (6) , pp. 2077-2087. 10.1523/JNEUROSCI.5249-09.2010
file

Hakobyan, Svetlana, Tortajada, Agustín, Harris, Claire Louise, de Córdoba, Santiago R and Morgan, Bryan Paul 2010. Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome. Kidney International 78 (8) , pp. 782-788. 10.1038/ki.2010.275

Ramaglia, Valeria, Tannemaat, Martijn Rudolf, de Kok, Maryla, Wolterman, Ruud, Vigar, Miriam Ann, King, Rosalind Helen Mary, Morgan, Bryan Paul and Baas, Frank 2009. Complement inhibition accelerates regeneration in a model of peripheral nerve injury. Molecular Immunology 47 (2-3) , pp. 302-309. 10.1016/j.molimm.2009.09.019

Tortajada, Agustin, Montes, Tamara, Martinez-Barricarte, Ruben, Morgan, Bryan Paul, Harris, Claire Louise and de Cordoba, Santiago Rodriguez 2009. The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Human Molecular Genetics 18 (18) , pp. 3452-3461. 10.1093/hmg/ddp289

Ramaglia, Valeria, King, Rosalind Helen Mary, Morgan, Bryan Paul and Baas, Frank 2009. Deficiency of the complement regulator CD59a exacerbates Wallerian degeneration. Molecular Immunology 46 (8-9) , pp. 1892-1896. 10.1016/j.molimm.2009.01.017

Hughes, Timothy Richard, Ross, Kirsty S., Cowan, Graeme J. M., Baalasubramanian, Sivasank, Harris, Claire Louise, Mitchell, Timothy J. and Morgan, Bryan Paul 2009. Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59. Molecular Immunology 46 (7) , pp. 1561-1567. 10.1016/j.molimm.2009.01.003

Montes, Tamara, Tortajada, Agustin, Morgan, Bryan Paul, Rodriguez de Cordoba, Santiago and Harris, Claire Louise 2009. Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B. Proceedings of the National Academy of Sciences 106 (11) , pp. 4366-4371. 10.1073/pnas.0812584106

Scola, Anne-Marie, Johswich, Kay-Ole, Morgan, Bryan Paul, Klos, Andreas and Monk, Peter N. 2009. The human complement fragment receptor, C5L2, is a recycling decoy receptor. Molecular Immunology 46 (6) , pp. 1149-1162. 10.1016/j.molimm.2008.11.001

Ruseva, Marieta Milkova, Hughes, Timothy Richard, Donev, Rossen Mintchev, Baalasubramanian, Sivasankar, Pickering, Matthew C., Wu, Xiaobo, Harris, Claire Louise and Morgan, Bryan Paul 2009. Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Molecular Immunology 46 (5) , pp. 803-811. 10.1016/j.molimm.2008.09.003

Kolev, Martin, Ruseva, Marieta Milkova, Harris, Claire Louise, Morgan, Bryan Paul and Donev, Rossen Mintchev 2009. Implication of complement system and its regulators in Alzheimer's Disease. Current Neuropharmacology 7 (1) , pp. 1-8.

Baalasubramanian, Sivasankar, Longhi, M. Paula, Gallagher, Kathleen M. E., Betts, Gareth J., Morgan, Bryan Paul, Godkin, Andrew James and Gallimore, Awen Myfanwy 2009. CD59 blockade enhances antigen-specific CD4+ T cell responses in humans: a new target for cancer immunotherapy? The Journal of Immunology 182 (9) , pp. 5203-5207. 10.4049/jimmunol.0804243

Arnold, D. F., Roberts, Andrew Glyn, Thomas, Anne Gwenllain, Ferry, B., Morgan, Bryan Paul and Chapel, H. 2009. A novel mutation in a patient with a deficiency of the eighth component of complement associated with recurrent meningococcal meningitis. Journal of Clinical Immunology 29 (5) , pp. 691-695. 10.1007/s10875-009-9295-7

Kolev, Martin, Tediose, Teeo, Baalasubramanian, Sivasankar, Harris, Claire Louise, Thome, J., Morgan, Bryan Paul and Donev, Rossen Mintchev 2009. Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration. The Pharmacogenomics Journal 10 (1) , pp. 12-19. 10.1038/tpj.2009.52

Ingram, Gillian, Hakobyan, Svetlana, Robertson, Neil and Morgan, Bryan Paul 2009. Complement in multiple sclerosis: its role in disease and potential as a biomarker. Clinical and Experimental Immunology 155 (2) , pp. 128-139. 10.1111/j.1365-2249.2008.03830.x

Stahel, Philip F, Flierl, Michael A, Morgan, Bryan Paul, Persigehl, Ivonne, Stoll, Christiane, Conrad, Claudia, Touban, Basel M, Smith, Wade R, Beauchamp, Kathryn, Schmidt, Oliver I, Ertel, Wolfgang and Leinhase, Iris 2009. Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice. Journal of Neuroinflammation 6 , pp. 2-13. 10.1186/1742-2094-6-2
file

Savage, D. B., Semple, R. K., Clatworthy, M. R., Lyons, P. A., Morgan, Bryan Paul, Cochran, E. K., Gorden, P., Raymond-Barker, P., Murgatroyd, P. R., Adams, C., Scobie, I., Mufti, G. J., Alexander, G. J. M., Thiru, S., Murano, I., Cinti, S., Chaudhry, A. N., Smith, K. G. C. and O'Rahilly, S. 2009. Complement Abnormalities in Acquired Lipodystrophy Revisited. Journal of Clinical Endocrinology & Metabolism 94 (1) , pp. 10-16. 10.1210/jc.2008-1703

McColl, Aisleen, Bournazos, Stylianos, Franz, Sandra, Perretti, Mauro, Morgan, Bryan Paul, Haslett, Christopher and Dransfield, Ian 2009. Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages. The Journal of Immunology 183 (3) , pp. 2167-2175. 10.4049/jimmunol.0803503

Mizuno, Masashi, Ito, Yasuhiko, Hepburn, Natalie Jayne, Mizuno, Tomohiro, Noda, Yukihiro, Yuzawa, Yukio, Harris, Claire Louise, Morgan, Bryan Paul and Matsuo, Seiichi 2009. Zymosan, but not lipopolysaccharide, triggers severe and progressive peritoneal injury accompanied by complement activation in a rat peritonitis model. The Journal of Immunology 183 (2) , pp. 1403-1412. 10.4049/jimmunol.0804245

Hakobyan, Svetlana, Harris, Claire Louise, Van Den Berg, Carmen Wilma, Fernandez-Alonso, Maria Carmen, de Jorge, Elena Goicoechea, de Cordoba, Santiago Rodriguez, Rivas, German, Mangione, Palma, Pepys, Mark B. and Morgan, Bryan Paul 2008. Complement factor H binds to denatured rather than to native pentameric C-reactive protein. Journal of Biological Chemistry 283 (45) , pp. 30451-30460. 10.1074/jbc.M803648200

Donev, Rossen Mintchev, Gray, Lisa Clare, Baalasubramanian, Sivasankar, Hughes, Timothy Richard, Van Den Berg, Carmen Wilma and Morgan, Bryan Paul 2008. Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma. Cancer Research 68 (14) , pp. 5979-5987. 10.1158/0008-5472.CAN-07-6828

Morton, Jonathan, Coles, Barbara, Wright, Kate Louise, Gallimore, Awen Myfanwy, Morrow, Jason D., Terry, Erin S., Anning, Peter, Morgan, Bryan Paul, Dioszeghy, Vincent, Kuhn, Hartmut, Chaitidis, Pavlos, Hobbs, Adrian J., Jones, Simon Arnett and O'Donnell, Valerie Bridget 2008. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN -dependent iNOS expression in the vasculature of healthy mice. Blood 111 (10) , pp. 5187-5194. 10.1182/blood-2007-10-117283

Ramaglia, Valeria, Wolterman, Ruud, de Kok, Maryla, Vigar, Miriam Ann, Wagenaar-Bos, Ineke, King, Rosalind Helen Mary, Morgan, Bryan Paul and Baas, Frank 2008. Soluble complement receptor 1 protects the peripheral nerve from early axon loss after injury. American Journal of Pathology 172 (4) , pp. 1043-1052. 10.2353/ajpath.2008.070660

Hepburn, Natalie Jayne, Ruseva, Marieta Milkova, Harris, Claire Louise and Morgan, Bryan Paul 2008. Complement, roles in renal disease and modulation for therapy. Clinical Nephrology 70 (5) , pp. 357-376.

Donev, Rossen Mintchev, Baalasubramanian, Sivasankar, Mizuno, Masashi and Morgan, Bryan Paul 2008. The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility. Molecular Immunology 45 (2) , pp. 534-542. 10.1016/j.molimm.2007.05.011

Hepburn, Natalie Jayne, Chamberlain-Banoub, Jayne L., Williams, Anwen Sian, Morgan, Bryan Paul and Harris, Claire Louise 2008. Prevention of experimental autoimmune myasthenia gravis by rat Crry-Ig: a model agent for long-term complement inhibition in vivo. Molecular Immunology 45 (2) , pp. 395-405. 10.1016/j.molimm.2007.06.144

Willison, Hugh J., Halstead, Susan K., Beveridge, Erin, Zitman, Femke M. P., Greenshields, Kay N., Morgan, Bryan Paul and Plomp, Jaap J. 2008. The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barré syndrome. Journal of Neuroimmunology 201 , pp. 172-182. 10.1016/j.jneuroim.2008.05.028

Leite, Maria Isabel, Jacob, Saiju, Viegas, Stuart, Cossins, Judy, Clover, Linda, Morgan, Bryan Paul, Beeson, David, Willcox, Nick and Vincent, Angela 2008. IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis. Brain 131 (7) , pp. 1940-1952. 10.1093/brain/awn092

Hakobyan, Svetlana, Harris, Claire Louise, Tortajada, Agustín, Goicochea de Jorge, Elena, Garcia-Layana, Alfredo, Fernandez-Robredo, Patricia, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul 2008. Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration. Investigative Ophthalmology and Visual Science 49 (5) , pp. 1983-1990. 10.1167/iovs.07-1523
file

Hepburn, Natalie Jayne, Williams, Anwen Sian, Morgan, Bryan Paul and Harris, Claire Louise 2007. In Vivo Characterization and Therapeutic Efficacy of a C5-specific Inhibitor from the Soft Tick Ornithodoros moubata. J Biol Chem 282 , pp. 8292-8299. 10.1074/jbc.M609858200

Harris, Claire Louise, Cordoba, S. Rodriguez de, Jorge, E. Goicoechea de and Morgan, Bryan Paul 2007. Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proceedings of the National Academy of Sciences 104 (1) , pp. 240-5. 10.1073/pnas.0603420103

Harris, Claire Louise, Morgan, Bryan Paul, Pettigrew, D.M. and Lea, S.M. 2007. Decay-accelerating factor must bind both components of the complement alternative pathway c3 convertase to mediate efficient decay. Journal of Immunology 178 , pp. 352-359.

Hepburn, Natalie J., Williams, Anwen Sian, Chamberlain, Jayne C., Hamer, Joseph, Nunn, M. A., Morgan, Bryan Paul and Harris, Claire Louise 2007. In vivo characterisation and therapeutic efficacy of a C5-specific inhibitor [Abstract]. Molecular Immunology 44 (1-3) , p. 183. 10.1016/j.molimm.2006.07.087

Mizuno, Masashi, Donev, Rossen Mark, Harris, Claire Louise and Morgan, Bryan Paul 2007. CD55 in rat male reproductive tissue: Differential expression in testis and expression of a unique truncated isoform on spermatozoa. Molecular Immunology 44 (7) , pp. 1613-1622. 10.1016/j.molimm.2006.08.018

Sivasankar, Baalasubramanian, Donev, Rossen Mintchev, Longhi, M. Paula, Hughes, Timothy Richard, Davies, Ruth, Cole, Duncan Sean, Morgan, Bryan Paul and Marchbank, Kevin J. 2007. CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens. Molecular Immunology 44 (11) , pp. 2978-2987. 10.1016/j.molimm.2006.12.025

Omidvar, Nader, Wang, Edward Chung Yern, Brennan, Paul, Longhi, M. Paula, Smith, Richard A. G. and Morgan, Bryan Paul 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. Journal of immunology 176 (5) , pp. 2915-2923.

Omidvar, Nader, Wang, Edward Chung Yern, Brennan, Paul, Longhi, Maria P., Smith, Richard A. G. and Morgan, Bryan Paul 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. The Journal of Immunology 176 (5) , pp. 2915-2923. 10.4049/jimmunol.176.5.2915

Donev, Rossen Mintchev, Cole, Duncan Sean, Sivanaskar, Baalasubramanian, Hughes, Timothy Richard and Morgan, B. Paul 2006. p53 regulates cellular resistance to complement lysis through enhanced expression of CD59. Cancer Research 66 (4) , pp. 2451-8. 10.1158/0008-5472.CAN-05-3191

Donev, Rossen Mintchev and Morgan, Bryan Paul 2006. A quantitative method for comparison of expression of alternatively spliced genes using different primer pairs. Journal of Biochemical and Biophysical Methods 66 (1-3) , pp. 23-31. 10.1016/j.jbbm.2005.11.001

Longhi, M. Paula, Baalasubramanian, Sivasankar, Omidvar, Nader, Morgan, Bryan Paul and Gallimore, Awen Myfanwy 2005. Cutting edge: murine CD59a modulates antiviral CD4+ T cell activity in a complement-independent manner. Journal of Immunology 175 (11) , pp. 7098-7102.

Harris, Claire Louise, Morgan, Bryan Paul, Lea, S. M. and Abbott, R. J. 2005. Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55). Journal of Biological Chemistry 280 (4) , pp. 2569-78. 10.1074/jbc.M410179200

Van Beek, J. and Morgan, Bryan Paul 2005. The role of complement in EAE. In: Lavi, E. and Constantinescu, C. S. eds. Experimental Models of Multple Sclerosis, Dordrecht: Kluwer Academic, pp. 245-267. (10.1007/0-387-25518-4_12)

Morgan, Bryan Paul, Griffiths, M., Khanom, H., Taylor, S. M. and Neal, James William 2004. Blockade of the C5a receptor fails to protect against experimental autoimmune encephalomyelitis in rats. Clinical & Experimental Immunology 138 (3) , pp. 430-8. 10.1111/j.1365-2249.2004.02646.x

Baalasubramanian, Sivasankar, Harris, Claire Louise, Donev, Rossen Mintchev, Mizuno, Masashi, Omidvar, Nader, Song, Wen-Chao and Morgan, Bryan Paul 2004. CD59a is the primary regulator of membrane attack complex assembly in the mouse. Journal of Immunology 173 , pp. 3684-3692.

Williams, Anwen Sian, Mizuno, Masashi, Richards, Peter James, Holt, Dewi Stanley and Morgan, Bryan Paul 2004. Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. Arthritis & Rheumatism 50 (9) , pp. 3035-3044. 10.1002/art.20478

Rushmere, N. K., Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Harper, Maureen Elaine, Robertson, J. F. R., Morgan, Bryan Paul and Nicholson, Robert Ian 2004. Analysis of the level of mRNA expression of the membrane regulators of complement, Cd59, Cd55 and Cd46, in breast, cancer. International Journal of Cancer 108 (6) , pp. 930-936. 10.1002/ijc.11606

Mead, Richard James, Neal, James William, Griffiths, Mark Raymond, Linington, Christopher, Botto, Marina, Lassmann, Hans and Morgan, Bryan Paul 2004. Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis. Laboratory Investigation 84 , pp. 21-28. 10.1038/labinvest.3700015

Harris, Claire Louise and Morgan, Bryan 2004. The many faces of the membrane regulators of complement. In: Szebeni, Janos ed. The Complement System: Novel Roles in Health and Disease, Boston: Kluwer, pp. 129-166.

Sivasankar, B., Mizuno, Masashi, Donev, Rossen Mintchev, Omidvar, Nader, Harris, Claire Louise, Song, W. C. and Morgan, Bryan Paul 2004. CD59b is expressed at low level on mouse erythrocytes and has a negligible protective role in the presence of CD59a. Molecular Immunology 41 (2-3) , pp. 307-308. 10.1016/j.molimm.2004.03.002

Harris, Claire Louise, Hughes, Clare Elizabeth, Williams, Anwen Sian, Goodfellow, Ian, Evans, David J., Caterson, Bruce and Morgan, Bryan Paul 2003. Generation of anti-complement 'prodrugs': cleavable reagents for specific delivery of complement regulators to disease sites. The Journal of Biological Chemistry 278 (38) , pp. 36068-36076. 10.1074/jbc.M306351200

Clayton, Aled, Harris, Claire Louise, Morgan, Bryan Paul and Mason, Malcolm David 2003. Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. European Journal of Immunology 33 (2) , pp. 522-31. 10.1002/immu.200310028

Spiller, Owen Bradley, Robinson, Mairi, O'Donnell, Elizabeth, Milligan, Steven, Morgan, Bryan Paul, Davison, Andrew J. and Blackbourn, David J. 2003. Complement regulation by Kaposi's sarcoma-associated herpesvirus ORF4 protein. Journal of Virology 77 (1) , pp. 592-599. 10.1128/JVI.77.1.592-599.2003

McGreal, Eamon Patrick, Ikawaki, N, Akatsu, H., Morgan, Bryan Paul and Gasque, Phillipe 2002. Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q. Journal of Immunology 168 , pp. 5222-5232.

Hiscox, Stephen Edward, Hallett, Maurice Bartlett, Morgan, Bryan Paul and Van Den Berg, Carmen Wilma 2002. GPI-anchored GFP signals Ca2+ but is homogeneously distributed on the cell surface. Biochemical and Biophysical Research Communications 293 (2) , pp. 714-721. 10.1016/S0006-291X(02)00280-2

Okosieme, Onyebuchi E., Parkes, Arthur Burnham, McCullough, B., Doukidis, D., Morgan, Bryan Paul, Richards, C. J. and Lazarus, John Henry 2002. Complement activation in postpartum thyroiditis. QJM: An International Journal of Medicine 95 (3) , pp. 173-179. 10.1093/qjmed/95.3.173

Mead, Richard James, Singhrao, Simarjit Kaur, Neal, James William, Lassmann, H. and Morgan, Bryan Paul 2002. The membrane attack complex of complement causes severe demyelination associated with acute axonal injury. Journal of Immunology 168 , pp. 458-465.

Holt, Dewi Stanley, Botto, M., Bygrave, A. E., Hanna, S. M., Walport, M. J. and Morgan, Bryan Paul 2001. Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria. Blood 98 (2) , pp. 442-9. 10.1182/blood.V98.2.442

Gasque, Philippe, Dean, Y. D., McGreal, Eamon Patrick, VanBeek, J. and Morgan, Bryan Paul 2000. Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology 49 (1-2) , pp. 171-186. 10.1016/S0162-3109(00)80302-1

Labeta, Mario, Vidal, K., Rey Nores, J. E., Arias, M., Vita, N., Morgan, Bryan Paul, Guillemot, J.C., Loyaux, D., Ferrara, P., Schmid, D., Affolter, M., Borysiewicz, L. K., Donnet-Hughes, A. and Schiffrin, E. J. 2000. Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14. Journal of Experimental Medicine 191 , pp. 1807-1812. 10.1084/jem.191.10.1807
file

Jones, J., Davies, E., Morgan, Bryan Paul and Hallett, Maurice Bartlett 1996. Effect of inhibitors of tyrosine kinase and phospholipase C on neutrophil response to perforin attack. Immunology 89 (Supp1) , R187-R187.

Van Den Berg, Carmen Wilma, Cinek, Tomas, Hallett, Maurice Bartlett, Horejsi, Vaclav and Morgan, Bryan Paul 1995. Exogenous CD59 incorporated into U937 cells through its glycosyl phosphatidylinositol anchor becomes associated with signalling molecules in a time dependent manner. Biochemical Society Transactions 23 (2) , 269S. 10.1042/bst023269s

Taylor, Kathryn Mary, Morgan, Bryan Paul and Campbell, Anthony Keith 1994. Altered glycosylation and selected mutation in recombinant human complement component C9: effects on haemolytic activity. Immunology 83 (3) , pp. 501-506.

This list was generated on Tue Dec 12 02:41:19 2017 GMT.