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Number of items: 72.

Davis, Terence 2019. Premature ageing in Werner syndrome - A central role for genomic instability induced-cellular senescence via p38 MAPK activation. In: Bernhardt, Leon V. ed. Advances in Medicine and Biology: Volume 143, New York: Nova Science, pp. 141-199.

Umbayev, Bauyrzhan, Masoud, Abdul-Razak, Tsoy, Andrey, Alimbetov, Dauren, Olzhayev, Farkhad, Shramko, Alla, Kaiyrlykyzy, Aiym, Safarova, Yuliya, Davis, Terence and Askarova, Sholpan 2018. Elevated levels of the small GTPase Cdc42 induces senescence in male rat mesenchymal stem cells. Biogerontology 19 (3-4) , pp. 287-301. 10.1007/s10522-018-9757-5
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Alimbetov, Dauren, Askarova, Sholpan, Umbayev, Bauyrzhan, Davis, Terence and Kipling, David 2018. Pharmacological targeting of cell cycle, apoptotic and cell adhesion signaling pathways implicated in chemoresistance of cancer cells. International Journal of Molecular Sciences 19 (6) , p. 1690. 10.3390/ijms19061690
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Davis, Terence, Brook, Amy Jayne Chedzoy, Rokicki, Michal Jaroslaw, Bagley, Mark and Kipling, David Glyn 2016. Evaluating the role of p38 MAPK in the accelerated cell senescence of Werner syndrome fibroblasts. Pharmaceuticals 9 (2) , 23. 10.3390/ph9020023
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Alimbetov, Dauren, Davis, Terence, Brook, Amy J. C., Cox, Lynne S., Faragher, Richard G. A., Nurgozhin, Talgat, Zhumadilov, Zhaxybay and Kipling, David Glyn 2016. Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2. Biogerontology 17 , 305. 10.1007/s10522-015-9610-z
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Bagley, Mark C., Dwyer, Jessica E., Baashen, Mohammed, Dix, Matthew C., Murziani, Paola G. S., Rokicki, Michal J., Kipling, David Glyn and Davis, Terence 2016. The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells. Organic & Biomolecular Chemistry 14 (3) , pp. 947-956. 10.1039/C5OB02229K
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Bagley, Mark, Baashen, Mohammed, Chuckowree, Irina, Dwyer, Jessica, Kipling, David Glyn and Davis, Terence 2015. Microwave-assisted synthesis of a MK2 inhibitor by Suzuki-Miyaura coupling for study in Werner Syndrome Cells. Pharmaceuticals 8 (2) , pp. 257-276. 10.3390/ph8020257
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Davis, Terence, Tivey, Hannah S.E., Brook, Amy J.C. and Kipling, David 2015. Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBNp70 protein undergo p38/MK2-dependent premature senescence. Biogerontology 16 (1) , pp. 43-51. 10.1007/s10522-014-9530-3
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Mark, Bagley, Mohammed, Baashen, Jessica, Dwyer, Pierre, Milbeo, Kipling, David Glyn and Davis, Terence 2014. Microwave-assisted Synthesis of Inhibitors of MK2 for Targeting p38 MAP Kinase Signalling in Werner Syndrome Cells. In: John, Spencer and Mark, Bagley eds. Microwaves in Drug Discovery and Development: Recent Advances, London: Future Medicine Ltd, pp. 86-104. (10.4155/fseb2013.13.130)

Davis, Terence 2014. Progeroid syndromes: role of accelerated fibroblast senescence and p38 activation. In: Hayat, M. A. ed. Tumor Dormancy and Cellular Quiescence and Senescence, Volume 3: Aging, Cancer, and Noncancer Pathologies, Berlin: Springer Verlag, pp. 25-39. (10.1007/978-94-017-9325-4_3)

Cox, Lynne S., Mason, Penelope A., Bagley, Mark C., Steinsalz, David, Stefanovska, Aneta, Bernjack, Alan, McClintock, Peter V. E., Phillips, Anna C., Upton, Jane, Latimer, Joanna Elizabeth and Davis, Terence 2014. Understanding ageing: biological and social constructions. In: Walker, Alan ed. The New Science of Ageing, Bristol: Policy Press,

Bagley, Mark C., Baashen, Mohammed, Paddock, Victoria L., Kipling, David Glyn and Davis, Terence 2013. Regiocontrolled synthesis of 3- and 5-aminopyrazoles, pyrazolo[3,4-d]pyrimidines, pyrazolo[3,4-b]pyridines and pyrazolo[3,4-b]quinolinones as MAPK inhibitors. Tetrahedron 69 (39) , pp. 8429-8438. 10.1016/j.tet.2013.07.055

Tivey, Hannah S. E., Brook, Amy Jayne Chedzoy, Rokicki, Michal Jaroslaw, Kipling, David Glyn and Davis, Terence 2013. p38 MAPK stress signalling in replicative senescence in fibroblasts from progeroid and genomic instability syndromes. Biogerontology 14 (1) , pp. 47-62. 10.1007/s10522-012-9407-2
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Davis, Terence, Rokicki, Michal Jaroslaw, Bagley, Mark C. and Kipling, David Glyn 2013. The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome. Chemistry Central Journal 7 , 18. 10.1186/1752-153X-7-18
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Davis, Terence, Tivey, Hannah, Brook, Amy Jayne Chedzoy, Grimstead, Julia W., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2013. Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome. AGE 35 (5) , pp. 1767-1783. 10.1007/s11357-012-9476-9
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Tivey, Hannah S. E., Rokicki, Michal Jaroslaw, Barnacle, James R., Rogers, Mathew James, Bagley, Mark C., Kipling, David Glyn and Davis, Terence 2013. Small molecule inhibition of p38 MAP kinase extends the replicative life span of human ATR-Seckel syndrome fibroblasts. The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 68 (9) , pp. 1001-1009. 10.1093/gerona/gls336
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Davis, Terence, Dix, Matthew Charles, Rokicki, Michal Jaroslaw, Brook, Amy Jayne Chedzoy, Widdowson, Caroline Susan, Kipling, David Glyn and Bagley, Mark Christopher 2011. Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors. Chemistry Central Journal 5 (1) , pp. 83-88. 10.1186/1752-153X-5-83

Bagley, Mark Christopher, Davis, Terence, Latimer, Joanna Elizabeth and Kipling, David Glyn 2011. The contribution of biogerontology to quality ageing. Quality in Ageing and Older Adults 12 (1) , pp. 26-32. 10.5042/qiaoa.2011.0142

Latimer, Joanna Elizabeth, Davis, Terence, Bagley, Mark Christopher and Kipling, David Glyn 2011. Ageing science, health care and social inclusion of older people. Quality in Ageing and Older Adults 12 (1) , pp. 11-16. 10.5042/qiaoa.2011.0140

Faragher, Richard G. A., Burton, Dominic G. A., Majecha, Patricia, Fong, Noel S. Y., Davis, Terence, Sheerin, Angela and Ostler, Elizabeth L. 2011. Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts. AGE 33 (4) , pp. 555-564. 10.1007/s11357-010-9201-5

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew, Fusillo, Vincenzo, Pigeaux, Morgane, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2010. Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome. Future Medicinal Chemistry 2 (9) , pp. 1417-1427. 10.4155/fmc.10.217

Bagley, Mark C., Davis, Terence, Murziani, Paola G. S., Widdowson, Caroline and Kipling, David Glyn 2010. Use of p38 MAPK inhibitors for the treatment of Werner Syndrome. Pharmaceuticals 3 (6) , pp. 1842-1872. 10.3390/ph3061842
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Bagley, Mark Christopher, Davis, Terence, Rokicki, Michal Jaroslaw, Widdowson, Caroline Susan and Kipling, David Glyn 2010. Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome. Future Medicinal Chemistry 2 (2) , pp. 193-201. 10.4155/fmc.09.163

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2010. Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells. Future Medicinal Chemistry 2 (2) , pp. 203-213. 10.4155/fmc.09.160

Davis, Terence, Bachler, Marcus Aurelius, Wyllie, Fiona Sandra, Bagley, Mark Christopher and Kipling, David 2010. Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts. Annals of the New York Academy of Sciences 1197 (1) , pp. 45-48. 10.1111/j.1749-6632.2010.05195.x

Davis, Terence, Tivey, Hannah S. E. and Kipling, David 2009. Telomere dynamics and biology in human progeroid syndromes. In: Mancini, Leonardo ed. Telomeres: Function, Shortening and Lengthening, New York: Nova Science Publishers, Inc., pp. 1-75.

Davis, Terence and Kipling, David Glyn 2009. Assessing the role of stress signalling via p38 MAP kinase in the premature senescence of Ataxia Telangiectasia and Werner syndrome fibroblasts. Biogerontology 10 (3) , pp. 253-266. 10.1007/s10522-008-9179-x
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Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Fusillo, Vincenzo, Pigeaux, Morgane, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2009. Microwave-assisted Ullmann C-S bond formation: synthesis of the P38 alpha MAPK clinical candidate VX-745. Journal of Organic Chemistry 74 (21) , pp. 8336-8342. 10.1021/jo9017155

Bagley, Mark Christopher, Davis, Terence, Dix, M. C., Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2008. Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 18 (13) , pp. 3745-3748. 10.1016/j.bmcl.2008.05.037

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2007. Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells. Biorganic and Medicinal Chemistry Letters 17 (18) , pp. 5107-5110. 10.1016/j.bmcl.2007.07.016

Davis, Terence, Wyllie, Fiona Sandra, Rokicki, Michal J., Bagley, Mark C. and Kipling, David Glyn 2007. The Role of Cellular Senescence in Werner Syndrome: Toward Therapeutic Intervention in Human Premature Aging. Annals of the New York Academy of Sciences 1100 , pp. 455-469. 10.1196/annals.1395.051

Davis, Terence., Bagley, Mark Christopher, Dix, M. C., Murziani, Paola G. S., Rokicki, M. J., Widdowson, C. S., Zayed, J. M., Bachler, M. A. and Kipling, David Glyn 2007. Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38 alpha(MAPK) inhibitors in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 17 (24) , pp. 6832-6835. 10.1016/j.bmcl.2007.10.036

Davis, Terence and Kipling, David Glyn 2007. Werner syndrome, telomeres, and stress signaling: implications for future therapies? In: Rudolph, K. Lenhard ed. Telomeres and Telomerase in Aging, Disease, and Cancer: Molecular Mechanisms of Adult Stem Cell Ageing, Springer, pp. 285-308.

Bagley, Mark C., Davis, Terence, Dix, Matthew C., Widdowson, Caroline S. and Kipling, David Glyn 2006. Microwave-assisted synthesis of N-pyrazole ureas and the p38α inhibitor BIRB 796 for study into accelerated cell ageing. Organic & Biomolecular Chemistry 4 (22) , pp. 4158-4164. 10.1039/b611493h

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Widdowson, Caroline S. and Kipling, David Glyn 2006. Microwave-assisted synthesis of N-pyrazole ureas and the p38 inhibitor BIRB 796 for study into accelerated cell ageing. Organic & biomolecular chemistry 4 (22) , pp. 4158-4164. 10.1039/b611493h

Davis, Terence and Kipling, David Glyn 2006. Werner Syndrome as an example of inflamm-aging: Possible therapeutic opportunities for a progeroid syndrome? Rejuvenation Research 9 (3) , pp. 402-407. 10.1089/rej.2006.9.402

Davis, Terence, Haughton, Michele F., Jones, Christopher J. and Kipling, David Glyn 2006. Prevention of accelerated cell aging in the Werner syndrome. Annals of the New York Academy of Sciences 1067 (1) , pp. 243-247. 10.1196/annals.1354.031

Davis, Terence and Kipling, David Glyn 2005. Telomeres and telomerase biology in vertebrates: Progress towards a non-human model for replicative senescence and ageing. Biogerontology 6 (6) , pp. 371-385. 10.1007/s10522-005-4901-4

Davis, Terence, Baird, Duncan Martin, Haughton, Michele Fleur, Jones, Christopher John and Kipling, David Glyn 2005. Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor. The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 60 (11) , pp. 1386-93.

Davis, Terence, Skinner, Julia W., Faragher, Richard G. A., Jones, Christopher J. and Kipling, David Glyn 2005. Replicative senescence in sheep fibroblasts is a p53 dependent process. Experimental Gerontology 40 (1-2) , pp. 17-26. 10.1016/j.exger.2004.09.004

Kipling, David Glyn, Davis, Terence, Ostler, Elizabeth L. and Faragher, Richard G. A. 2004. What can progeroid syndromes tell us about human aging? Science 305 (5689) , pp. 1426-1431. 10.1126/science.1102587

Baird, Duncan Martin, Davis, Terence, Rowson, Janet Maud, Jones, Christopher John and Kipling, David Glyn 2004. Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells. Human Molecular Genetics 13 (14) , pp. 1515-1524. 10.1093/hmg/ddh159
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Davis, Terence, Faragher, Richard G. A., Jones, Christopher J. and Kipling, David Glyn 2004. Investigation of the signaling pathways involved in the proliferative life span barriers in Werner syndrome fibroblasts. Annals of the New York Academy of Sciences 1019 (1) , pp. 274-277. 10.1196/annals.1297.046

Davis, Terence 2003. Use of cross-species genome comparison to deduce possible importance of the various D. melanogaster fruitless transcripts: a putative vital function for the type C transcription factor? Drosophila Information Service 86 , pp. 133-136.

Davis, Terence 2003. The genes of the elbow-no-ocelli genetic complex in D. melanogaster. Drosophila Information Service 86 , pp. 126-128.

Davis, Terence, Singhrao, Simarjit Kaur, Wyllie, Fiona Sandra, Haughton, Michele Fleur, Smith, Paul James, Wiltshire, Marie, Wynford-Thomas, David, Jones, Christopher John, Faragher, Richard G. A. and Kipling, David Glyn 2003. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms. Journal of Cell Science (JCS) 116 (7) , pp. 1349-57. 10.1242/jcs.00331
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Davis, Terence 2002. Comparison of the sexual behaviour gene fruitless between D. melanogaster and two sympatric Hawaiian species, D. heteroneura and D. silvestris. Drosophila Information Service 85 , pp. 25-28.

Edwards, Kevin, Davis, Terence, Marcey, David, Kurihara, Joyce and Yamamoto, Daisuke 2001. Comparative analysis of the Band 4.1/ezrin-related protein tyrosine phosphatase Pez from two Drosophila species: implications for structure and function. Gene 275 (2) , pp. 195-205. 10.1016/S0378-1119(01)00686-2

Davis, Terence and Ito, H. 2001. Genomic structure of the sexual behaviour gene fruitless. Drosophila Information Service 84 , pp. 65-66.

Gailey, Donald A., Ho, Sun K., Ohshima, Saiyou, Liu, Jim H., Eyassu, Meraf, Washington, Michael A., Yamamoto, Daisuke and Davis, Terence 2000. Brief report a phylogeny of the Drosophilidae using the sex-behaviour gene fruitless. Hereditas 133 (1) , pp. 81-83. 10.1111/j.1601-5223.2000.00081.x

Davis, Terence 2000. On the relationship between the Scaptomyza and the Hawaiian Drosophila [Brief report]. Hereditas 132 (3) , pp. 257-259. 10.1111/j.1601-5223.2000.00257.x

Davis, Terence, Kurihara, Joyce and Yamamoto, Daisuke 2000. Genomic organisation and characterisation of the neural sex-determination gene fruitless (fru) in the Hawaiian species Drosophila heteroneura. Gene 246 (1-2) , pp. 143-149. 10.1016/S0378-1119(00)00064-0

Davis, Terence, Kurihara, Joyce, Yoshino, Erin and Yamamoto, Daisuke 2000. Genomic organisation of the neural sex determination gene fruitless (fuu) in the Hawaiian species Drosophila siluestris and the conservation of the fru BTB protein-protein-binding domain throughout evolution. Hereditas 132 (1) , pp. 67-78. 10.1111/j.1601-5223.2000.00067.x

Ashburner, M., Misra, S., Roote, J., Lewis, S. E., Blazej, R., Davis, Terence, Doyle, C., Galle, R., George, R., Harris, N., Hartzell, G., Harvey, D., Hong, L., Houston, K., Hoskins, R., Johnson, G., Martin, C., Moshrefi, A., Palazzolo, M., Reese, M. G., Spradling, A., Tsang, G., Wan, K., Whitelaw, K., Kimmel, B., Celniker, S. and Rubin, G. M. 1999. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics 153 (1) , pp. 179-219.

Helps, N. R., Brewis, N. D., Lineruth, K., Davis, Terence, Kaiser, K. and Cohen, P. T. 1998. Protein phosphatase 4 is an essential enzyme required for organisation of microtubules at centrosomes in Drosophila embryos. Journal of Cell Science 111 (10) , pp. 1331-1340.

Trikka, D., Davis, Terence, Lapenta, V., Brahe, C. and Kessling, A. M. 1997. Human COL6A1: Genomic characterization of the globular domains, structural and evolutionary comparison with COL6A2. Mammalian Genome 8 (5) , pp. 342-345. 10.1007/s003359900436

Davis, Terence, Ashburner, Michael, Johnson, Glynnis, Gubb, David and Roote, John 1997. Genetic and phenotypic analysis of the genes of the elbow-no-ocelli region of chromosome 2L of Dvosophila melanogaster. Hereditas 126 (1) , pp. 67-75. 10.1111/j.1601-5223.1997.00067.x

Faragher, R. G. A., Hardy, S. P., Davis, Terence, Dropcova, S. and Allen, M. C. 1997. Cycling Werner's syndrome fibroblasts display calcium-dependent potassium currents. Experimental Cell Research 231 (1) , pp. 119-122. 10.1006/excr.1996.3437

Davis, Terence and Shall, Sydney 1997. Characterisation and expression of a chicken erythroblast mono(ADP-ribosyl)transferase gene [Meeting abstract]. Biochemical Society Transactions 25 (1) , 80S-80S. 10.1042/bst025080s

Davis, Terence, Sabir, Jamal S. M., Tavassoli, Manoochehr and Shall, Sydney 1997. Purification, characterisation, and molecular cloning of a chicken erythroblast mono(ADP-ribosyl)transferase. Advances in Experimental Medicine and Biology 419 , pp. 145-154. 10.1007/978-1-4419-8632-0_17

McNabb, S., Grieg, S. and Davis, Terence 1996. The alcohol dehydrogenase gene is nested in the outspread locus of Drosophila melanogaster. Genetics 143 (2) , pp. 897-911.

Davis, Terence and Ashburner, Michael 1996. The chromosomal organisation of the alcohol dehydrogenase region of the genome of Drosophila melanogaster [Communication]. Biochemical Society Transactions 24 (1) , 109S-109S. 10.1042/bst024109s

Davis, Terence and Shall, Sydney 1995. Sequence of a chicken erythroblast mono(ADP-ribosyl)transferase-encoding gene and its upstream region [Brief note]. Gene 164 (2) , pp. 371-372. 10.1016/0378-1119(95)00504-Y

Davis, Terence and Shall, Sydney 1995. Cloning of a chicken gene homologous to the rabbit mono-ADP-ribosyltransferase gene [Communication]. Biochemical Society Transactions 23 (2) , 207S-207S. 10.1042/bst023207s

Davis, Terence and Lineruth, Katrin 1994. The characterisation of a P-element insert into the Gsα G protein gene in Drosophila melanogaster [Communication]. Biochemical Society Transactions 22 (2) , 134S-134S. 10.1042/bst022134s

Lineruth, Katrin and Davis, Terence 1992. The isolation and characterization of P-element insertions into G protein genes [Communication]. Biochemical Society Transactions 20 (3) , 261S-261S. 10.1042/bst020261s

Gubb, D., Ashburner, M., Roote, J. and Davis, Terence 1990. A novel transvection phenomenon affecting the white gene of Drosophila melanogaster. Genetics 126 (1) , pp. 167-176.

Davis, Terence, Trenear, J. and Ashburner, M. 1990. The molecular analysis of the el-noc complex of Drosophila melanogaster. Genetics 126 (1) , pp. 105-119.

Adams, Roger L. P., Davis, Terence, Rinaldi, Angela and Eason, Robert 1987. CpG deficiency, dinucleotide distributions and nucleosome positioning. European Journal of Biochemistry 165 (1) , pp. 107-115. 10.1111/j.1432-1033.1987.tb11200.x

Davis, Terence, Rinaldi, Angela, Clark, Lilian and Adams, Roger L. P. 1986. Methylation of chromatin in vitro. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 866 (4) , pp. 233-241. 10.1016/0167-4781(86)90048-5

Davis, Terence, Kirk, David, Rinaldi, Angela, Burdon, Roy H. and Adams, Roger L. P. 1985. Delayed methylation and the matrix bound DNA methylase. Biochemical and Biophysical Research Communications 126 (2) , pp. 678-684. 10.1016/0006-291X(85)90238-4

Adams, R. L., Davis, Terence, Fulton, J., Kirk, D., Qureshi, M. and Burdon, R. H. 1984. Eukaryotic DNA methylase--properties and action on native DNA and chromatin. Current Topics in Microbiology and Immunology 108 , pp. 143-156. 10.1007/978-3-642-69370-0_10

This list was generated on Thu Oct 17 05:20:43 2019 BST.