Liang, Sheng-Ru, Cai, Jing, Yang, Yang, Zhang, Lei, Taylor, Peter, Ming, Jie, Yu, Xin-Wen, Hu, Ruo-Fan, Zhou, Jie, Dayan, Colin M. and Ji, Qiu-He 2022. Relationship between thyroid hormones and metabolic syndrome in a normal thyroid function population in Western China. Chinese Medical Journal 135 (3) , pp. 350-352. 10.1097/CM9.0000000000001553 |
Zhang, Lei, Rai, Pavandeep, Miwa, Satomi, Draman, Mohd, Rees, D Aled, Haridas, Anjana S., Morris, Daniel S., Tee, Andrew R., Ludgate, Marian, Turnbull, Doug M. and Dayan, Colin M. 2021. The role of mitochondria-linked fatty-acid uptake-driven adipogenesis in Graves’ Orbitopathy. Endocrinology 162 (12) , bqab188. 10.1210/endocr/bqab188 |
Zhang, Lei, Evans, Anna, von Ruhland, Chris, Draman, Mohd Shazli, Edkins, Sarah, Vincent, Amy E., Berlinguer-Palmini, Rolando, Rees, D. Aled, Haridas, Anjana S, Morris, Dan, Tee, Andrew R., Ludgate, Marian, Turnbull, Doug M., Karpe, Fredrik and Dayan, Colin M. 2020. Distinctive features of orbital adipose tissue (OAT) in Graves' orbitopathy. International Journal of Molecular Sciences 21 (23) , 9145. 10.3390/ijms21239145 |
Lowe, John, Gillespie, David, Hubbard, Marie, Zhang, Lei, Kirby, Nigel, Pickles, Timothy, Thomas-Jones, Emma, Turner, Mark A., Klein, Nigel, Marchesi, Julian R., Hood, Kerenza, Berrington, Janet and Kotecha, Sailesh 2020. Study protocol: azithromycin therapy for chronic lung disease of prematurity (AZTEC) - a randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants. BMJ Open 10 (10) , e041528. 10.1136/bmjopen-2020-041528 |
Taylor, Peter N., Zhang, Lei, Lee, Richard W. J., Muller, Ilaria, Ezra, Daniel G., Dayan, Colin M., Kahaly, George J. and Ludgate, Marian 2019. New insights into the pathogenesis and nonsurgical management of Graves orbitopathy. Nature Reviews Endocrinology 16 (2) , pp. 104-116. 10.1038/s41574-019-0305-4 |
Wilson, Nicholas, Steadman, Robert, Muller, Ilaria, Draman, Mohd, Rees, D. Aled, Taylor, Peter, Dayan, Colin M., Ludgate, Marian and Zhang, Lei 2019. Role of hyaluronan in human adipogenesis: Evidence from in-vitro and in-vivo studies. International Journal of Molecular Sciences 20 (11) , 2675. 10.3390/ijms20112675 |
Draman, Mohd Shazli, Morris, Daniel S, Evans, Sam, Haridas, Anjana, Pell, Julie, Greenwood, Rosemary, Foy, Chris, Taylor, Peter, Pooprasert, Pakinee, Muller, Ilaria, Zhang, Lei, Lane, Carol, Okosieme, Onyebuchi, Ludgate, Marian and Dayan, Colin 2019. Prostaglandin F2-alpha eye drops (bimatoprost) in Graves' orbitopathy: a randomized controlled double-masked crossover trial (BIMA Trial). Thyroid Journal Program 29 (4) , pp. 563-572. 10.1089/thy.2018.0506 |
Muller, Ilaria, Willis, Mark, Healy, Sarah, Nasser, Taha, Loveless, Samantha, Butterworth, Sara, Zhang, Lei, Draman, Mohd S., Taylor, Peter N., Robertson, Neil, Dayan, Colin M. and Ludgate, Marian E. 2018. Longitudinal characterization of autoantibodies to the thyrotropin receptor (TRAb) during alemtuzumab therapy; evidence that TRAb may precede thyroid dysfunction by many years. Thyroid 28 (12) , pp. 1682-1693. 10.1089/thy.2018.0232 |
Bakhsh, Ameen D., Ladas, Ioannis, Hamshere, Marian L., Bullock, Martyn, Kirov, George, Zhang, Lei, Taylor, Peter N., Gregory, John W., Scott-Coombes, David, Völzke, Henry, Teumer, Alexander, Mantripragada, Kiran, Williams, E. Dillwyn, Clifton-Bligh, Roderick J., Williams, Nigel M. and Ludgate, Marian E. 2018. An InDel in Phospholipase-C-B-1 is linked with euthyroid multinodular goiter. Thyroid 28 (7) , pp. 891-901. 10.1089/thy.2017.0312 |
Zhang, Lei, Masetti, Giulia, Colucci, Giuseppe, Salvi, Mario, Covelli, Danila, Eckstein, Anja, Kaiser, Ulrike, Draman, Mohd Shazli, Muller, Ilaria, Ludgate, Marian, Lucini, Luigi and Biscarini, Filippo 2018. Combining micro-RNA and protein sequencing to detect robust biomarkers for Graves' disease and orbitopathy. Scientific Reports 8 (1) , 8386. 10.1038/s41598-018-26700-1 |
Hales, Charlotte, Taylor, Peter N., Channon, Sue, Paradice, Ruth, McEwan, Kirsten, Zhang, Lei, Gyedu, Michael, Bakhsh, Ameen, Okosieme, Onyebuchi, Muller, Ilaria, Draman, Mohd S., Gregory, John W., Dayan, Colin, Lazarus, John H., Rees, D. Aled and Ludgate, Marian 2018. Controlled antenatal thyroid screening II: effect of treating maternal sub-optimal thyroid function on child cognition. Journal of Clinical Endocrinology and Metabolism 103 (4) , pp. 1583-1591. 10.1210/jc.2017-02378 |
Draman, Mohd Shazli, Stechman, Michael, Scott-Coombes, David, Dayan, Colin M., Rees, Dafydd Aled, Ludgate, Marian and Zhang, Lei 2017. The role of thyrotropin receptor activation in adipogenesis and modulation of fat phenotype. Frontiers in Endocrinology 8 , 83. 10.3389/fendo.2017.00083 |
Bullock, Martyn, Lim, Grace, Li, Cheng, Ho Choi, In, Kochhar, Shivansh, Liddle, Chris, Zhang, Lei and Clifton-Bligh, Roderick J. 2016. Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT. Oncotarget 7 , pp. 85948-85962. 10.18632/oncotarget.13288 |
Ruffino, J. S., Davies, N. A., Morris, K., Ludgate, Marian, Zhang, Lei, Webb, R. and Thomas, A. W. 2016. Moderate-intensity exercise alters markers of alternative activation in circulating monocytes in females: a putative role for PPARγ. European Journal of Applied Physiology 116 (9) , pp. 1671-1682. 10.1007/s00421-016-3414-y |
Muller, Ilaria, Zhang, Lei, Giani, C, Dayan, Colin Mark, Ludgate, Marian Elizabeth and Grennan-Jones, F. 2016. The sodium iodide symporter is unlikely to be a thyroid/breast shared antigen. Journal of Endocrinological Investigation 39 (3) , pp. 323-331. 10.1007/s40618-015-0368-6 |
Zhang, Lei, Ji, Q. H. J., Ruge, Fiona, Lane, C., Morris, D., Tee, Andrew, Dayan, Colin Mark and Ludgate, Marian Elizabeth 2015. Reversal of pathological features of Graves' orbitopathy by activation of forkhead transcription factors, FOXOs. Journal of Clinical Endocrinology & Metabolism 101 (1) , pp. 114-122. 10.1210/jc.2015-2932 |
Zhang, Lei, Grennan-Jones, Fiona, Draman, M.S., Lane, C., Morris, D., Dayan, Colin, Tee, Andrew and Ludgate, Marian Elizabeth 2014. Possible targets for nonimmunosuppressive therapy of Graves' orbitopathy. Journal of Clinical Endocrinology & Metabolism 99 (7) , E1183-E1190. 10.1210/jc.2013-4182 |
Muller, I., Giani, C., Zhang, Lei, Grennan-Jones, F. A, Fiore, E., Belardi, V., Rosellini, V., Funel, N., Campani, D., Giustarini, E., Lewis, M. D., Bakhsh, A. D., Roncella, M., Ghilli, M., Vitti, P., Dayan, C. M. and Ludgate, M. E. 2014. Does thyroid peroxidase provide an antigenic link between thyroid autoimmunity and breast cancer? International Journal of Cancer 134 (7) , pp. 1706-1714. 10.1002/ijc.28493 |
Ming, Jie, Xu, Shaoyong, Yang, Chao, Gao, Bin, Wan, Yi, Xing, Ying, Zhang, Lei, Yang, Wenying and Ji, Qiuhe 2014. Metabolic syndrome and chronic kidney disease in general Chinese adults: Results from the 2007-08 China National Diabetes and Metabolic Disorders Study. Clinica Chimica Acta 430 , pp. 115-120. 10.1016/j.cca.2014.01.004 |
Xu, Shaoyong, Ming, Jie, Yang, Chao, Gao, Bin, Wan, Yi, Xing, Ying, Zhang, Lei and Ji, Qiuhe 2014. Urban, semi-urban and rural difference in the prevalence of metabolic syndrome in Shaanxi province, northwestern China: a population-based survey. BMC Public Health 14 (1) , 104. 10.1186/1471-2458-14-104 |
Draman, Mohd, Grennan-Jones, Fiona, Zhang, Lei, Taylor, Peter, Tun, T., McDermott, J., Moriarty, P., Morris, D., Lane, C., Sreenan, S., Dayan, Colin and Ludgate, Marian Elizabeth 2013. Effects of Prostaglandin F2a on adipocyte biology relevant to graves' orbitopathy. Thyroid: official journal of the American Thyroid Association 23 (12) , pp. 1600-1608. 10.1089/thy.2013.0194 |
Zhang, Lei and Ludgate, Marian E. 2012. The search for biomarkers of disease: surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, tears, and thyroid-associated ophthalmopathy. Thyroid: official journal of the American Thyroid Association 22 (10) , pp. 981-983. 10.1089/thy.2012.2210.ed2 |
Zhang, Lei, Grennan-Jones, Fiona Antoinette, Lane, Carol, Rees, Dafydd Aled, Dayan, Colin Mark and Ludgate, Marian Elizabeth 2012. Adipose tissue depot-specific differences in the regulation of hyaluronan production of relevance to Graves' orbitopathy. Journal of Clinical Endocrinology & Metabolism 97 (2) , pp. 653-662. 10.1210/jc.2011-1299 |
Rice, Samuel Peter Llewellyn, Zhang, Lei, Grennan-Jones, Fiona Antoinette, Agarwal, Neera, Lewis, Mark David, Rees, Dafydd Aled and Ludgate, Marian Elizabeth 2010. Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue. Molecular and Cellular Endocrinology 320 (1-2) , pp. 51-57. 10.1016/j.mce.2010.02.017 |
Zhang, Lei, Bowen, Timothy, Grennan-Jones, Fiona Antoinette, Paddon, Carol Ann, Giles, Peter James, Webber, Jason P., Steadman, Robert and Ludgate, Marian Elizabeth 2009. Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: Contributory role in hyaluronan accumulation in thyroid dysfunction. Journal of Biological Chemistry 284 (39) , pp. 26447-26455. 10.1074/jbc.M109.003616 |
Zhang, Lei, Paddon, Carol Ann, Lewis, Mark David, Grennan-Jones, Fiona Antoinette and Ludgate, Marian Elizabeth 2009. Gsα signalling suppresses PPARγ2 generation and inhibits 3T3L1 adipogenesis. Journal of Endocrinology 202 (2) , pp. 207-215. 10.1677/JOE-09-0099 |
Cozma, Irina, Zhang, Lei, Uddin, James, Lane, Carol, Rees, Dafydd Aled and Ludgate, Marian Elizabeth 2007. Modulation of expression of somatostatin receptor subtypes in Graves' opthalmopathy orbits : relevance to novel analogues. American Journal of Physiology. Endocrinology and Metabolism 10.1152/ajpendo.00177.2007 |
Roder, Karim, Zhang, Lei and Schweizer, Michael 2007. SREBP-1c mediates the retinoid-dependent increase in fatty acid synthase promoter activity in HepG2. FEBS Letters 581 (14) , pp. 2715-2720. 10.1016/j.febslet.2007.05.022 |
Zhang, Lei, Baker, Glynn, Janus, Dominika, Paddon, Carol A., Fuhrer, Dagmar and Ludgate, Marian 2006. Biological effects of thyrotropin receptor activation on human orbital dreadipocytes. Investigative Ophthalmology & Visual Science 47 (12) , pp. 5197-5203. 10.1167/iovs.06-0596 |
Schweizer, M., Roder, K., Zhang, Lei and Wolf, S. S. 2002. Transcription factors acting on the promoter of the rat fatty acid synthase gene. Biochemical Society Transactions 30 (6) , p. 1070. 10.1042/bst0301070 |