Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by All Cardiff Authors

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Number of items: 16.

Beswick, Paul, Wahab, Ben, Honey, Mark A., Paradowski, Michael, Jiang, Ke, Lochner, Martin, Murrell-Lagnado, Ruth D. and Thompson, Andrew J. 2019. A challenge finding P2X1 and P2X4 ligands. Neuropharmacology 157 , p. 107674. 10.1016/j.neuropharm.2019.107674
file

West, Ryan A., O'Doherty, Oran G., Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E., Rao, Srinivasa P.S., Williams, Gareth and Ward, Simon 2017. African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase. European Journal of Medicinal Chemistry 141 , pp. 676-689. 10.1016/j.ejmech.2017.09.067
file

Hornyak, P., Askwith, T., Walker, S., Komulainen, E., Paradowski, Michael, Pennicott, L. E., Bartlett, E. J., Brissett, N. C., Raoof, A., Watson, M., Jordan, A. M., Ogilvie, D. J., Ward, Simon, Atack, J. R., Pearl, L. H., Caldecott, K. W. and Oliver, A. W. 2016. Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal 473 (13) , pp. 1869-1879. 10.1042/BCJ20160180
file

Re:Viral Ltd 2016. Spiro-indolines for the treatment and prophylaxis of respiratory syncytial virus infection (RSV). WO2016055780A1. [Patent].

Moore, Thomas O., Paradowski, Michael and Ward, Simon 2016. An atom-efficient and convergent approach to the preparation of NS5A inhibitors by C-H activation. Organic and Biomolecular Chemistry 14 (12) , pp. 3307-3313. 10.1039/C6OB00340K
file

Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R., Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Goetz, Gilles H., Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob and Pryde, David C. 2014. The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile—part 2. ChemMedChem 9 (7) , pp. 1387-1396. 10.1002/cmdc.201400046

Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A., Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P., Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob and Pryde, David C. 2014. The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 1. ChemMedChem 9 (7) , pp. 1378-1386. 10.1002/cmdc.201400045

Burrows, Andrew D., Jurcic, Monika, Keenan, Luke L., Lane, Rebecca A., Mahon, Mary F., Warren, Mark R., Nowell, Harriott, Paradowski, Michael and Spencer, John 2013. Incorporation by coordination and release of the iron chelator drug deferiprone from zinc-based metal-organic frameworks. Chemical Communications 49 (96) , pp. 11260-11262. 10.1039/c3cc45689g

Lane, Charlotte A.L., Hay, Duncan, Mowbray, Charles E., Paradowski, Michael, Selby, Matthew D., Swain, Nigel A. and Williams, David H. 2012. Synthesis of novel histamine H4 receptor antagonists. Bioorganic and Medicinal Chemistry Letters 22 (2) , pp. 1156-1159. 10.1016/j.bmcl.2011.11.098

Egan, Ben A., Paradowski, Michael, Thomas, Lynne H. and Marquez, Rodolfo 2011. http://dx.doi.org/10.1016/j.tet.2011.10.036. Tetrahedron 67 (50) , pp. 9700-9707. 10.1016/j.tet.2011.10.036

Hay, Duncan A., Adam, Fiona M., Bish, Gerwyn, Calo, Frederick, Dixon, Rachel, Fray, M. Jonathan, Hitchin, James, Jones, Peter, Paradowski, Michael, Parsons, Gemma C., Proctor, Katie J.W., Pryde, David C., Smith, Nicholas N. and Tran, Thien-Duc 2011. A flexible synthesis of C-6 and N-1 analogues of a 4-amino-1,3-dihydroimidazo[4,5-c]pyridin-2-one core. Tetrahedron Letters 52 (44) , pp. 5728-5732. 10.1016/j.tetlet.2011.08.119

Mowbray, Charles E., Bell, Andrew S., Clarke, Nicholas P., Collins, Michelle, Jones, Rhys M., Lane, Charlotte A.L., Liu, Wai L., Newman, Sandra D., Paradowski, Michael, Schenck, Emanuel J., Selby, Mathew D., Swain, Nigel A. and Williams, David H. 2011. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: A novel histamine H4 receptor antagonist. Bioorganic and Medicinal Chemistry Letters 21 (21) , pp. 6596-6602. 10.1016/j.bmcl.2011.07.125

Adam, Fiona M., Bish, Gerwyn, Calo, Frederick, Carr, Christopher L., Castro, Nieves, Hay, Duncan, Hodgson, Paul B., Jones, Peter, Knight, Craig J., Paradowski, Michael, Parsons, Gemma C., Proctor, Katie J. W., Pryde, David C., Rota, Filippo, Smith, Mya C., Smith, Nicholas, Tran, Thien-Duc, Hitchin, James and Dixon, Rachel 2011. Development of a practical synthesis of toll-like receptor agonist PF-4171455: 4-Amino-1-benzyl-6-trifluoromethyl-1,3-dihydroimidazo [4,5-c] pyridin-2-one. Organic Process Research and Development 15 (4) , pp. 788-796. 10.1021/op200021a

Egan, Ben A., Paradowski, Michael, Thomas, Lynne H. and Marquez, Rodolfo 2011. Regiocontrolled rearrangement of isobenzofurans. Organic Letters 13 (8) , pp. 2086-2089. 10.1021/ol200498k

Pryde, David C., Tran, Thien-Duc, Jones, Peter, Parsons, Gemma C., Bish, Gerwyn, Adam, Fiona M., Smith, Mya C., Middleton, Donald S., Smith, Nick N., Calo, Frederick, Hay, Duncan, Paradowski, Michael, Proctor, Katie J. W., Parkinson, Tanya, Laxton, Carl, Fox, David N. A., Horscroft, Nigel J., Ciaramella, Giuseppe, Jones, Hannah M., Duckworth, Jonathan, Benson, Neil, Harrison, Anthony and Webster, Rob 2011. The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection. MedChemComm 2 (3) , p. 185. 10.1039/C0MD00197J

Paradowski, Michael, Lane, Charlotte and Peakman, Torren 2011. Synthesis of a Novel Octahydro Pyrrolo[3,4-c]pyrrole Cyclic Amidine via 1,3-Dipolar Cycloaddition of Azomethine Ylides. SYNLETT 2011 (11) , pp. 1543-1546. 10.1055/s-0030-1260768

This list was generated on Thu Dec 5 08:22:12 2019 GMT.