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Number of items: 61.

Allen, Benjamin D. W., Mishra, Deepak, Seastram, Alex C., McBride, Tom, Wirth, Thomas, Browne, Duncan L. and Morrill, Louis C. 2019. Manganese-catalyzed electrochemical deconstructive chlorination of cycloalkanols via alkoxy radicals. Organic Letters 21 (22) , pp. 9241-9246. 10.1021/acs.orglett.9b03652
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Galaverna, Renan, McBride, Tom, Pastre, Julio C. and Browne, Duncan L. 2019. Exploring the generation and use of acylketenes with continuous flow processes. Reaction Chemistry and Engineering 4 (9) , pp. 1559-1564. 10.1039/C9RE00072K
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Cao, Qun, Stark, Roderick, Fallis, Ian and Browne, Duncan L. 2019. A ball-milling enabled Reformatsky reaction. ChemSusChem 12 (12) , pp. 2554-2557. 10.1002/cssc.201900886
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Laudadio, Gabriele, Barmpoutsis, Efstathios, Schotten, Christiane, Struik, Lisa, Govaerts, Sebastian, Browne, Duncan L. and Noël, Timothy 2019. Sulfonamide synthesis through electrochemical oxidative coupling of amines and thiols. Journal of the American Chemical Society 141 (14) , pp. 5664-5668. 10.1021/jacs.9b02266
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Cao, Qun, Nicholson, William I., Jones, Andrew C. and Browne, Duncan L. 2019. Robust Buchwald-Hartwig amination enabled by ball-milling. Organic and Biomolecular Chemistry 17 (7) , pp. 1722-1726. 10.1039/C8OB01781F
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Carden, Jamie, Gierlichs, Lukas, Wass, Duncan, Browne, Duncan and Melen, Rebecca 2019. Unlocking the catalytic potential of tris(3,4,5-trifluorophenyl)borane with microwave irradiation. Chemical Communications 55 (3) , pp. 318-321. 10.1039/C8CC09459D
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Howard, Joseph L., Brand, Michael C. and Browne, Duncan L. 2018. Switching chemoselectivity: Using mechanochemistry to alter reaction kinetics. Angewandte Chemie International Edition 57 (49) , pp. 16104-16108. 10.1002/anie.201810141
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Galaverna, Renan, Fernandes, Lucas P., Browne, Duncan L. and Pastre, Julio C. 2018. Continuous flow processing as a tool for the generation of terpene-derived monomer libraries. Reaction Chemistry and Engineering 4 (2) , pp. 362-367. 10.1039/C8RE00237A
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Schotten, Christiane, Howard, Joseph L., Jenkins, Robert L., Codina, Anna and Browne, Duncan L. 2018. A continuous flow-batch hybrid reactor for commodity chemical synthesis enabled by inline NMR and temperature monitoring. Tetrahedron 74 (38) , pp. 5503-5509. 10.1016/j.tet.2018.05.070
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Cao, Qun, Howard, Joseph L., Crawford, Deborah E., James, Stuart L. and Browne, Duncan L. 2018. Translating solid state organic synthesis from a mixer mill to a continuous twin screw extruder. Green Chemistry 20 (19) , pp. 4443-4447. 10.1039/C8GC02036A
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Cao, Qun, Howard, Joseph L., Wheatley, Emilie and Browne, Duncan L. 2018. Mechanochemical activation of zinc and application to Negishi cross-coupling. Angewandte Chemie - International Edition 57 (35) , pp. 11339-11343. 10.1002/anie.201806480
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Howard, Joseph L., Sagatov, Yerbol and Browne, Duncan L. 2018. Mechanochemical electrophilic fluorination of liquid beta-ketoesters. Tetrahedron 74 (25) , pp. 3118-3123. 10.1016/j.tet.2017.11.066
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Howard, Joseph, Cao, Qun and Browne, Duncan 2018. Mechanochemistry as an emerging tool for molecular synthesis: what can it offer? Chemical Science 9 (12) , pp. 3080-3094. 10.1039/C7SC05371A
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Schotten, Christiane, Leist, Lisa G. T., Semrau, Anna Lisa and Browne, Duncan L. 2018. A machine-assisted approach for the preparation of follow-on pharmaceutical compound libraries. Reaction Chemistry and Engineering 3 (2) , pp. 210-215. 10.1039/C8RE00010G
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Howard, Joseph L., Nicholson, William, Sagatov, Yerbol and Browne, Duncan L. 2017. One-pot multistep mechanochemical synthesis of fluorinated pyrazolones. Beilstein Journal of Organic Chemistry 13 , pp. 1950-1956. 10.3762/bjoc.13.189
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Jürgens, Sophie, Scalcon, Valeria, Estrada-Ortiz, Natalia, Folda, Alessandra, Tonolo, Federica, Jandl, Christian, Browne, Duncan L., Rigobello, Maria Pia, Kühn, Fritz E. and Casini, Angela 2017. Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes. Bioorganic & Medicinal Chemistry 10.1016/j.bmc.2017.08.001
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Wilkins, Lewis, Howard, Joseph, Burger, Stefan, Frentzel-Beyme, Louis, Browne, Duncan and Melen, Rebecca 2017. Exploring multistep continuous flow hydrosilylation reactions catalyzed by tris(pentafluorophenyl)borane. Advanced Synthesis & Catalysis 359 (15) , pp. 2580-2584. 10.1002/adsc.201700349
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Pope, Simon J., Groves, Lara, Schotten, Christiane, Beames, Joseph, Platts, James, Browne, Duncan, Coles, Simon and Horton, Peter 2017. From ligand to phosphor: rapid, machine-assisted syntheses of substituted iridium(III)-pyrazolate complexes with tuneable luminescence. Chemistry - a European Journal 23 (39) , pp. 9407-9418. 10.1002/chem.201701551
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Howard, Joseph L., Sagatov, Yerbol, Repusseau, Laura, Schotten, Christiane and Browne, Duncan L. 2017. Controlling reactivity through liquid assisted grinding: the curious case of mechanochemical fluorination. Green Chemistry 12 , pp. 2798-2802. 10.1039/C6GC03139K
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Howard, Joseph L., Schotten, Christiane and Browne, Duncan L. 2017. Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing. Reaction Chemistry and Engineering 2 (3) , pp. 281-287. 10.1039/C7RE00034K
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Browne, Duncan L, Howard, Joseph L and Schotten, Christiane 2017. Continuous flow processing as a tool for medicinal chemical synthesis. Comprehensive Medicinal Chemistry III, Elsevier, pp. 135-185. (10.1016/B978-0-12-409547-2.12288-7)

Schotten, Christiane, Aldmairi, Abdul Hadi, Sagatov, Yerbol, Shepherd, Martyn and Browne, Duncan L. 2016. Protected diazonium salts: a continuous-flow preparation of triazenes including the anticancer compounds dacarbazine and mitozolomide. Journal of Flow Chemistry 6 (3) , pp. 218-225. 10.1556/1846.2016.00025
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Browne, Duncan L. and Richardson, Paul 2016. Chapter 15. Fluorination Approaches. In: Blakemore, D, Doyle, P, Fobian, Y and Thurston, D eds. Synthetic Methods in Drug Discovery: Volume 2, Vol. 2. Synthetic Methods in Drug Discovery, Cambridge, UK: Royal Society of Chemistry, pp. 263-357. (10.1039/9781782627913-00263)

Browne, Duncan L., Ley, Steven V., Poh, Jian-Siang, Blakemore, David C., Meroni, Francesca, García-Ruiz, Cristina and Zuniga, Andrea 2016. Synthesis of trifluoromethylated isoxazoles and their elaboration through inter- and intra-molecular C-H arylation. Organic & Biomolecular Chemistry 14 (25) , pp. 5983-5991. 10.1039/C6OB00970K
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Howard, Joseph L., Schotten, Christiane, Alston, Stephen T. and Browne, Duncan L. 2016. Preparation of difluoromethylthioethers through difluoromethylation of disulfides using TMS-CF2H. Chemical Communications 52 , pp. 8448-8451. 10.1039/C6CC02693A
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Poh, Jian-Siang, Browne, Duncan L. and Ley, Steven V. 2016. A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process. Reaction Chemistry and Engineering 2016 (1) , pp. 101-105. 10.1039/C5RE00082C
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Browne, Duncan L. 2015. Flow chemistry. Green Processing and Synthesis 4 (3) , p. 253. 10.1515/gps-2015-0027

Schotten, Christiane, Plaza, Dorota, Manzini, Simone, Nolan, Steven P., Ley, Steven V., Browne, Duncan L. and Lapkin, Alexei 2015. Continuous flow metathesis for direct valorization of food waste: an example of cocoa butter triglyceride. ACS Sustainable Chemistry & Engineering 3 (7) , pp. 1453-1459. 10.1021/acssuschemeng.5b00397
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Zhou, Yating, Guo, Fang, Hughes, Colan Evan, Browne, Duncan L., Peskett, Thomas R. and Harris, Kenneth David Maclean 2015. Discovery of new metastable polymorphs in a family of urea co-crystals by solid-state mechanochemistry. Crystal Growth and Design 15 (6) , pp. 2901-2907. 10.1021/acs.cgd.5b00331

Deadman, Benjamin J., Browne, Duncan L., Baxendale, Ian R. and Ley, Steven V. 2015. Back pressure regulation of slurry-forming reactions in continuous flow. Chemical Engineering & Technology 38 (2) , pp. 259-264. 10.1002/ceat.201400445

Browne, Duncan L. 2015. Cluster preface: progress in organo-fluorine chemistry. Synlett 26 (01) , pp. 33-35. 10.1055/s-0034-1379721

Newby, James A., Blaylock, D. Wayne, Witt, Paul M., Turner, Richard M., Heider, Patrick L., Harji, Bashir H., Browne, Duncan L. and Ley, Steven V. 2014. Reconfiguration of a continuous flow platform for extended operation: application to a cryogenic fluorine-directedortho-lithiation reaction. Organic Process Research and Development 18 (10) , pp. 1221-1228. 10.1021/op500221s

Kabeshov, Mikhail A., Musio, Biagia, Murray, Philip R. D., Browne, Duncan L. and Ley, Steven V. 2014. Expedient preparation of nazlinine and a small library of indole alkaloids using flow electrochemistry as an enabling technology. Organic Letters 16 (17) , pp. 4618-4621. 10.1021/ol502201d

Newby, James A., Blaylock, D. Wayne, Witt, Paul M., Pastre, Julio C., Zacharova, Marija K., Ley, Steven V. and Browne, Duncan L. 2014. Design and application of a low-temperature continuous flow chemistry platform. Organic Process Research and Development 18 (10) , pp. 1211-1220. 10.1021/op500213j

Browne, Duncan 2014. The Trifluoromethylating Sandmeyer Reaction: a method for transforming C[BOND]N into C[BOND]CF3. Angewandte Chemie - International Edition 53 (6) , pp. 1482-1484. 10.1002/anie.201308997

Newby, James A., Huck, Lena, Blaylock, D. Wayne, Witt, Paul M., Ley, Steven V. and Browne, Duncan L. 2014. Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor. Chemistry - a European Journal 20 (1) , pp. 263-271. 10.1002/chem.201303736

Allwood, Daniel, Browne, Duncan L. and Ley, Steven V. 2014. Synthesis and Use of a Trifluoromethylated Azomethine Ylide Precursor: Ethyl 1-Benzyl-trans-5-(trifluoromethyl)pyrrolidine-3-carboxylate. Organic Syntheses 91 , pp. 162-174.

Pastre, Julio C., Browne, Duncan L. and Ley, Steven V. 2013. Flow chemistry syntheses of natural products. Chemical Society Reviews 42 (23) , pp. 8849-8869. 10.1039/c3cs60246j

Murray, Philip R. D., Browne, Duncan L., Pastre, Julio C., Butters, Chris, Guthrie, Duncan and Ley, Steven V. 2013. Continuous flow-processing of organometallic reagents using an advanced peristaltic pumping system and the telescoped flow synthesis of (E/Z)-tamoxifen. Organic Process Research and Development 17 (9) , pp. 1192-1208. 10.1021/op4001548

Pastre, Julio C., Browne, Duncan L., O'Brien, Matthew and Ley, Steven V. 2013. Scaling up of continuous flow processes with gases using a tube-in-tube reactor: inline titrations and fanetizole synthesis with ammonia. Organic Process Research and Development 17 (9) , pp. 1183-1191. 10.1021/op400152r

Ley, Steven V., Ingham, Richard J., O'Brien, Matthew and Browne, Duncan L. 2013. Camera-enabled techniques for organic synthesis. Beilstein Journal of Organic Chemistry 9 , pp. 1051-1072. 10.3762/bjoc.9.118

Ley, Steven, Nakayama, Keiji, Browne, Duncan L. and Baxendale, Ian 2013. Studies of a Diastereoselective Electrophilic Fluorination Reaction Employing a Cryo-Flow Reactor. Synlett 24 (10) , pp. 1298-1302. 10.1055/s-0033-1338455

Tran, Gaël, Meier, Robin, Harris, Lawrence, Browne, Duncan L. and Ley, Steven V. 2012. Synthesis and use of a trifluoromethylated azomethine ylide precursor. Journal of Organic Chemistry 77 (24) , pp. 11071-11078. 10.1021/jo302052m

Browne, Duncan L., Wright, Steven, Deadman, Benjamin J., Dunnage, Samantha, Baxendale, Ian R., Turner, Richard M. and Ley, Steven V. 2012. Continuous flow reaction monitoring using an on-line miniature mass spectrometer. Rapid Communications in Mass Spectrometry 26 (17) , pp. 1999-2010. 10.1002/rcm.6312

O'Brien, Matthew, Koos, Peter, Browne, Duncan L. and Ley, Steven V. 2012. A prototype continuous-flow liquid–liquid extraction system using open-source technology. Organic & Biomolecular Chemistry 10 (35) , pp. 7031-7036. 10.1039/c2ob25912e

Koos, Peter, Browne, Duncan L. and Ley, Steven V. 2012. Continuous stream processing: a prototype magnetic field induced flow mixer. Green Processing and Synthesis 1 (1) , pp. 11-18. 10.1515/greenps-2011-0501

Ley, Steven, Browne, Duncan L., O'Brien, Matthew, Koos, Peter, Cranwell, Philippa and Polyzos, Anastasios 2012. Continuous-flow processing of gaseous ammonia using a teflon AF-2400 tube-in-tube reactor: synthesis of thioureas and in-line titrations. Synlett 23 (09) , pp. 1402-1406. 10.1055/s-0031-1290963

Cranwell, Philippa B., O'Brien, Matthew, Browne, Duncan L., Koos, Peter, Polyzos, Anastasios, Peña-López, Miguel and Ley, Steven V. 2012. Flow synthesis using gaseous ammonia in a Teflon AF-2400 tube-in-tube reactor: Paal–Knorr pyrrole formation and gas concentration measurement by inline flow titration. Organic & Biomolecular Chemistry 10 (30) , pp. 5774-5779. 10.1039/c2ob25407g

Browne, Duncan L., Baxendale, Ian R. and Ley, Steven V. 2011. Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines. Tetrahedron 67 (52) , pp. 10296-10303. 10.1016/j.tet.2011.09.146

Browne, Duncan L., Baumann, Marcus, Harji, Bashir H., Baxendale, Ian R. and Ley, Steven V. 2011. A new enabling technology for convenient laboratory scale continuous flow processing at low temperatures. Organic Letters 13 (13) , pp. 3312-3315. 10.1021/ol2010006

Browne, Duncan L., Deadman, Benjamin J., Ashe, Robert, Baxendale, Ian R. and Ley, Steven V. 2011. Continuous flow processing of slurries: evaluation of an agitated cell reactor. Organic Process Research and Development 15 (3) , pp. 693-697. 10.1021/op2000223

Crossley, James A., Kirkham, James D., Browne, Duncan L. and Harrity, Joseph P.A. 2010. On the use of 2-(trimethylsilyl)iodobenzene as a benzyne precursor. Tetrahedron Letters 51 (50) , pp. 6608-6610. 10.1016/j.tetlet.2010.10.052

Crossley, James A. and Browne, Duncan L. 2010. An alkynyliodide cycloaddition strategy for the construction of iodoisoxazoles. Journal of Organic Chemistry 75 (15) , pp. 5414-5416. 10.1021/jo1011174

Crossley, James A. and Browne, Duncan L. 2010. Cycloaddition of benzynes and nitrile oxides: synthesis of benzisoxazoles. Tetrahedron Letters 51 (17) , pp. 2271-2273. 10.1016/j.tetlet.2010.02.103

Browne, Duncan L. and Harrity, Joseph P. A. 2010. Recent developments in the chemistry of sydnones. Tetrahedron 66 (3) , pp. 553-568. 10.1016/j.tet.2009.10.085

Browne, Duncan L., Taylor, John B., Plant, Andrew and Harrity, Joseph P. A. 2010. Alkyne [3 + 2] cycloadditions of iodosydnones toward functionalized 1,3,5-trisubstituted pyrazoles. Journal of Organic Chemistry 75 (3) , pp. 984-987. 10.1021/jo902514v

Foster, Robert S., Huang, Jianhui, Vivat, Jérôme F., Browne, Duncan L. and Harrity, Joseph P. A. 2009. A divergent strategy to the withasomnines. Organic & Biomolecular Chemistry 7 (19) , pp. 4052-4056. 10.1039/b910632d

Browne, Duncan L., Vivat, Jérôme F., Plant, Andrew, Gomez-Bengoa, Enrique and Harrity, Joseph P. A. 2009. Investigation of the scope and regiochemistry of alkynylboronate cycloadditions with sydnones. Journal of the American Chemical Society 131 (22) , pp. 7762-7769. 10.1021/ja902460n

Browne, Duncan L., Taylor, John B., Plant, Andrew and Harrity, Joseph P. A. 2009. Cross coupling of bromo sydnones: development of a flexible route toward functionalized pyrazoles. Journal of Organic Chemistry 74 (1) , pp. 396-400. 10.1021/jo802240e

Delaney, Patrick M., Browne, Duncan L., Adams, Harry, Plant, Andrew and Harrity, Joseph P.A. 2008. A 2-pyrone cycloaddition route to functionalised aromatic boronic esters. Tetrahedron 64 (5) , pp. 866-873. 10.1016/j.tet.2007.08.118

Browne, Duncan L., Helm, Matthew D., Plant, Andrew and Harrity, Joseph P.A. 2007. A sydnone cycloaddition route to pyrazole boronic esters. Angewandte Chemie - International Edition 46 (45) , pp. 8656-8658. 10.1002/anie.200703767

This list was generated on Mon Dec 9 09:50:59 2019 GMT.