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Number of items: 30.

Oliva, Paola, Romagnoli, Romeo, Manfredini, Stefano, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Ronca, Roberto, Maccarinelli, Federica, Giacomini, Arianna, Rruga, Fatlum, Mariotto, Elena, Viola, Giampietro and Bortolozzi, Roberta 2020. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors. European Journal of Medicinal Chemistry 200 , 112448. 10.1016/j.ejmech.2020.112448
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Manganaro, Roberto, Zonsics, Birgit, Bauer, Lisa, Lorenzo Lopez, Moira, Donselaar, Tim, Zwaagstra, Marleen, Saporito, Fabiana, Ferla, Salvatore, Strating, Jeroen R. P. M., Coutard, Bruno, Hurdiss, Daniel L., van Kuppeveld, Frank J. M. and Brancale, Andrea 2020. Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors. Antiviral Research 178 , 104781. 10.1016/j.antiviral.2020.104781
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Zhao, Fei, Masci, Domiziana, Ferla, Salvatore, Varricchio, Carmine, Brancale, Andrea, Colonna, Serena, Black, Gary W., Turner, Nicholas J. and Castagnolo, Daniele 2020. Monoamine oxidase (MAO-N) biocatalyzed synthesis of indoles from indolines prepared via photocatalytic cyclization/arylative dearomatization. ACS Catalysis 10 (11) , pp. 6414-6421. 10.1021/acscatal.0c01351
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Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Kimatrai Salvador, Maria, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Viola, Giampietro, Bortolozzi, Roberta, Persoons, Leentje, Balzarini, Jan, Liekens, Sandra and Schols, Dominique 2020. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization. Bioorganic Chemistry 97 , 103665. 10.1016/j.bioorg.2020.103665

Ferla, Salvatore, Manganaro, Roberto, Benato, Sara, Paulissen, Jasmine, Neyts, Johan, Jochmans, Dirk, Brancale, Andrea and Bassetto, Marcella 2020. Rational modifications, synthesis and biological evaluation of new potential antivirals for RSV designed to target the M2-1 protein. Bioorganic and Medicinal Chemistry 28 (8) , 115401. 10.1016/j.bmc.2020.115401
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Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Cacciari, Barbara, Balzarini, Jan, Liekens, Sandra, Hamel, Ernest, Brancale, Andrea, Ferla, Salvatore, Manfredini, Stefano, Zurlo, Matteo, Finotti, Alessia and Gambari, Roberto 2020. Synthesis and biological evaluation of new antitubulin agents containing 2-(3?,4?,5?-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine scaffold. Molecules 25 (7) , 1690. 10.3390/molecules25071690
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Albulescu, Irina C., White-Scholten, Leonie, Tas, Ali, Hoornweg, Tabitha E., Ferla, Salvatore, Kovacikova, Kristina, Smit, Jolanda M., Brancale, Andrea, Snijder, Eric J. and van Hemert, Martijn J. 2020. Suramin inhibits Chikungunya virus replication by interacting with virions and blocking the early steps of infection. Viruses 12 (3) , 314. 10.3390/v12030314
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Giancotti, Gilda, Rigo, Ilaria, Pasqualetto, Gaia, Young, Mark T., Neyts, Johan, Rocha-Pereira, Joana, Brancale, Andrea, Ferla, Salvatore and Bassetto, Marcella 2019. A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase. Scientific Reports 9 (1) , 18413. 10.1038/s41598-019-54903-7
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Whatley, Kezia C. L., Padalino, Gilda, Whiteland, Helen, Geyer, Kathrin K., Hulme, Benjamin J., Chalmers, Iain W., Forde-Thomas, Josephine, Ferla, Salvatore, Brancale, Andrea and Hoffmann, Karl F. 2019. The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets. PLOS Neglected Tropical Diseases 13 (11) , e0007693. 10.1371/journal.pntd.0007693
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Pertusati, Fabrizio, Ferla, Salvatore, Bassetto, Marcella, Brancale, Andrea, Kandil, Sahar, Westwell, Andrew D. and McGuigan, Christopher 2019. A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer. European Journal of Medicinal Chemistry 180 , pp. 1-14. 10.1016/j.ejmech.2019.07.001
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Płaszczyca, Anna, Scaturro, Pietro, Neufeldt, Christopher John, Cortese, Mirko, Cerikan, Berati, Ferla, Salvatore, Brancale, Andrea, Pichlmair, Andreas and Bartenschlager, Ralf 2019. A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle. PLoS Pathogens 15 (5) , e1007736. 10.1371/journal.ppat.1007736
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Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Baraldi, Pier Giovanni, Schiaffino Ortega, Santiago, Chayah, Mariem, Kimatrai Salvador, Maria, Lopez-Cara, Luisa Carlota, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Ronca, Roberto, Bortolozzi, Roberta, Mariotto, Elena, Mattiuzzo, Elena and Viola, Giampietro 2019. Design, synthesis, and biological evaluation of 6-Substituted Thieno[3,2-d]pyrimidine analogues as dual epidermal growth factor receptor kinase and microtubule inhibitors. Journal of Medicinal Chemistry 62 (3) , pp. 1274-1290. 10.1021/acs.jmedchem.8b01391
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Bauer, Lisa, Ferla, Salvatore, Head, Sarah A., Bhat, Shridhar, Pasunooti, Kalyan K., Shi, Wei Q., Albulescu, Lucian, Liu, Jun O., Brancale, Andrea, van Kuppeveld, Frank J.M. and Strating, Jeroen R.P.M. 2018. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Research 156 , pp. 55-63. 10.1016/j.antiviral.2018.05.010
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Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Baraldi, Pier Giovanni, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Bortolozzi, Roberta and Viola, Giampietro 2018. 3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. design, synthesis, antiproliferative activity and inhibition of tubulin polymerization. Bioorganic Chemistry 80 , pp. 361-374. 10.1016/j.bioorg.2018.06.037
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Ferla, Salvatore, Netzler, Natalie E., Ferla, Sebastiano, Veronese, Sofia, Tuipulotu, Daniel Enosi, Guccione, Salvatore, Brancale, Andrea, White, Peter A. and Bassetto, Marcella 2018. In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase. Scientific Reports 8 (4129) , 4129. 10.1038/s41598-018-22303-y
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Slusarczyk, Magdalena, Ferla, Salvatore, Brancale, Andrea and McGuigan, Christopher 2018. Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides. Bioorganic and Medicinal Chemistry 26 (3) , pp. 551-565. 10.1016/j.bmc.2017.11.037
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Ferrara, M., Sessa, G., Fiore, M., Bernard, F., Asteriti, I. A., Cundari, E., Colotti, G., Ferla, S., Desideri, M., Buglioni, S., Trisciuoglio, D., Del Bufalo, D., Brancale, A. and Degrassi, F. 2018. Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization. Oncogene 37 , pp. 231-240. 10.1038/onc.2017.320
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Romagnoli, Romeo, Kimatrai Salvador, Maria, Schiaffino Ortega, Santiago, Baraldi, Pier Giovanni, Oliva, Paola, Baraldi, Stefania, Lopez-Cara, Luisa Carlota, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Balzarini, Jan, Liekens, Sandra, Mattiuzzo, Elena, Basso, Giuseppe and Viola, Giampietro 2018. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition. European Journal of Medicinal Chemistry 143 , pp. 683-698. 10.1016/j.ejmech.2017.11.096
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Lauder, Sarah N., Allen-Redpath, Keith, Slatter, David A., Aldrovandi, Maceler, O'Connor, Anne, Farewell, Daniel, Percy, Charles L., Molhoek, Jessica E., Rannikko, Sirpa, Tyrrell, Victoria J., Ferla, Salvatore, Milne, Ginger L., Poole, Alastair W., Thomas, Christopher P., Obaji, Samya, Taylor, Philip R., Jones, Simon A., deGroot, Philip G., Urbanus, Rolf T., Horkko, Sohvi, Uderhardt, Stefan, Ackermann, Jochen, Jenkins, P. Vince, Brancale, Andrea, Kronke, Gerhard, Collins, Peter W. and O'Donnell, Valerie B. 2017. Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis. Science Signaling 10 (507) , eaan2787. 10.1126/scisignal.aan2787
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Netzler, Natalie E., Enosi Tuipulotu, Daniel, Eltahla, Auda A., Lun, Jennifer H., Ferla, Salvatore, Brancale, Andrea, Urakova, Nadya, Frese, Michael, Strive, Tanja, Mackenzie, Jason M. and White, Peter A. 2017. Broad-spectrum non-nucleoside inhibitors for caliciviruses. Antiviral Research 146 , pp. 65-75. 10.1016/j.antiviral.2017.07.014
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Bassetto, Marcella, Ferla, Salvatore, Giancotti, Gilda, Pertusati, Fabrizio, Westwell, Andrew D., Brancale, Andrea and McGuigan, Christopher 2017. Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents. MedChemComm 8 (7) , pp. 1414-1420. 10.1039/C7MD00164A
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Brancale, Andrea, Shailubhai, Kunwar, Ferla, Salvatore, Ricci, Antonio, Bassetto, Marcella and Jacob, Gary S. 2017. Therapeutically targeting guanylate cyclase-C: computational modeling of plecanatide, a uroguanylin analog. Pharmacology Research & Perspectives 5 (2) , e00295. 10.1002/prp2.295
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Romagnoli, Romeo, Baraldi, Pier Giovanni, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Salvador, Maria Kimatrai, Lopez-Cara, Luisa Carlota, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Ronca, Roberto, Bortolozzi, Roberta, Mariotto, Elena, Porcù, Elena, Basso, Giuseppe and Viola, Giampietro 2017. Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents. Scientific Reports 7 , 46356. 10.1038/srep46356
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Bassetto, Marcella, Ferla, Salvatore, Pertusati, Fabrizio, Kandil, Sahar, Westwell, Andrew, Brancale, Andrea and McGuigan, Christopher 2016. Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer. European Journal of Medicinal Chemistry 118 , pp. 230-243. 10.1016/j.ejmech.2016.04.052
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Ferla, Salvatore, Bassetto, Marcella, Pertusati, Fabrizio, Kandil, Sahar, Westwell, Andrew D., Brancale, Andrea and McGuigan, Christopher 2016. Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety. Bioorganic and Medicinal Chemistry Letters 26 (15) , pp. 3636-3640. 10.1016/j.bmcl.2016.06.001
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Romagnoli, Romeo, Baraldi, Pier Giovanni, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Tabrizi, Mojgan Aghazadeh, Lopez-Cara, Luisa Carlota, Ferla, Salvatore, Brancale, Andrea, Hamel, Ernest, Ronca, Roberto, Bortolozzi, Roberta, Mariotto, Elena, Basso, Giuseppe and Viola, Giampietro 2016. Design and synthesis of potent in vitro and in vivo anticancer agents based on 1-(3′,4′,5′-Trimethoxyphenyl)- 2-Aryl-1H-Imidazole. Scientific Reports 6 , p. 26602. 10.1038/srep26602
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Grande, Fedora, Parisi, Ortensia I., Mordocco, Roberta A., Rocca, Carmine, Puoci, Francesco, Scrivano, Luca, Quintieri, Anna M., Cantafio, Patrizia, Ferla, Salvatore, Brancale, Andrea, Saturnino, Carmela, Cerra, Maria C., Sinicropi, Maria S. and Angelone, Tommaso 2016. Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization. European Journal of Pharmaceutical Sciences 82 , pp. 161-170. 10.1016/j.ejps.2015.11.021
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Ferla, Salvatore, Gomaa, Mohamed S., Brancale, Andrea, Zhu, Jinge, Ochalek, Justin T., DeLuca, Hector F. and Simons, Claire 2014. Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation. European Journal of Medicinal Chemistry 87 , pp. 39-51. 10.1016/j.ejmech.2014.09.035
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Ferla, Salvatore, Aboraia, Ahmed S., Brancale, Andrea, Pepper, Christopher J., Zhu, Jinge, Ochalek, Justin T., DeLuca, Hector F. and Simons, Claire 2014. Small-molecule inhibitors of 25-Hydroxyvitamin D-24-Hydroxylase (CYP24A1): synthesis and biological evaluation. Journal of Medicinal Chemistry 57 (18) , pp. 7702-7715. 10.1021/jm5009314
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Ferla, Salvatore 2013. Small molecule inhibitors of CYP24A1 for the treatment of various cancers. PhD Thesis, Cardiff University.
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This list was generated on Tue Sep 22 06:10:04 2020 BST.