ORCA
Online Research @ Cardiff
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Number of items: 27.
| Faraldos, Juan, Grundy, Daniel, Cascon Salgado, Oscar, Leoni, Stefano, van der Kamp, Marc W and Allemann, Rudolf 2016. Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate. Chemical Communications 52 (97) , pp. 14027-14030. 10.1039/C6CC08164A |
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| Gonzalez, Veronica, Grundy, Daniel J., Faraldos, Juan A. and Allemann, Rudolf Konrad 2016. The amino-terminal segment in the β-domain of δ-cadinene synthase is essential for catalysis. Organic & Biomolecular Chemistry 14 (31) , pp. 7451-7454. 10.1039/C6OB01398H |
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| Chen, Mengbin, Chou, Wayne K. W., Al-Lami, Naeemah, Faraldos, Juan, Allemann, Rudolf, Cane, David E. and Christianson, David W. 2016. Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry 55 (20) , pp. 2864-2874. 10.1021/acs.biochem.6b00343 |
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| Salmon, Melissa, Laurendon, Caroline, Vardakou, Maria, Cheema, Jitender, Defernez, Marianne, Green, Sol, Faraldos, Juan Antonio and O'Maille, Paul E. 2015. Emergence of terpene cyclization in Artemisia annua. Nature Communications 6 , 6143. 10.1038/ncomms7143 |
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Gonzalez, Veronica, Touchet, Sabrina, Grundy, Daniel J., Faraldos, Juan A. and Allemann, Rudolf K.
2014.
Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-Germacrene A synthase.
Journal of the American Chemical Society
136
(41)
, pp. 14505-14512.
10.1021/ja5066366
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| Giannakopoulou, Artemis, Schornack, Sebastian, Bozkurt, Tolga O., Haart, Dave, Ro, Dae-Kyun, Faraldos, Juan A., Kamoun, Sophien and O'Maille, Paul E. 2014. Variation in capsidiol sensitivity between Phytophthora infestans and Phytophthora capsici is consistent with their host range. PLoS ONE 9 (9) , e107462. 10.1371/journal.pone.0107462 |
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| Vardakou, Maria, Salmon, Melissa, Faraldos, Juan A. and O'Maille, Paul E. 2014. Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases. MethodsX 1 , pp. 187-196. 10.1016/j.mex.2014.08.007 |
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| Faraldos, Juan A., Coates, Robert M. and Giner, José-Luis 2013. Alternative synthesis of the Colorado potato beetle pheromone. Journal of Organic Chemistry 78 (20) , pp. 10548-10554. 10.1021/jo4017056 |
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| Li, Jian-Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang-Qing, Wang, Ling-Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao-Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from 'Artemisia annua': Product specificity and catalytic efficiency. Biochemical Journal 451 (3) , pp. 417-426. 10.1042/BJ20130041 |
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| Li, Jian‑Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang‑Qing, Wang, Ling‑Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao‑Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochemical Journal -London- 451 (3) , pp. 417-426. 10.1042/BJ20130041 |
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| Chen, Mengbin, Al-Lami, Naeemah, Janvier, Marine, D'Antonio, Edward L., Faraldos, Juan A., Cane, David E., Allemann, Rudolf Konrad and Christianson, David W. 2013. Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry 52 (32) , pp. 5441-5453. 10.1021/bi400691v |
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| Cascón, Oscar, Touchet, Sabrina, Miller, David James, Gonzalez, Veronica, Faraldos, Juan A. and Allemann, Rudolf Konrad 2012. Chemoenzymatic preparation of germacrene analogues. Chemical Communications 48 (78) , pp. 9702-9704. 10.1039/c2cc35542f |
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| Faraldos, Juan A., Miller, David James, Gonzalez, Veronica, Yoosuf-Aly, Fathima Zulfa, Cascón, Oscar, Li, Amang and Allemann, Rudolf Konrad 2012. A 1,6-ring closure mechanism for (+)-δ-cadinene synthase? Journal of the American Chemical Society 134 (13) , pp. 5900-5908. 10.1021/ja211820p |
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| Yoosuf-Aly, Zulfa, Faraldos, Juan A., Miller, David James and Allemann, Rudolf Konrad 2012. Chemoenzymatic synthesis of the alarm pheromone (+)-verbenone from geranyl diphosphate. Chemical Communications 48 , pp. 7040-7042. 10.1039/c2cc32883f |
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| Faraldos, Juan A., Gonzalez, Veronica, Li, Amang, Yu, Fanglei, Köksal, Mustafa, Christianson, David W. and Allemann, Rudolf Konrad 2012. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. Journal of the American Chemical Society 134 (51) , pp. 20844-20848. 10.1021/ja311022s |
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| Faraldos, Juan A., Gonzalez, Veronica and Allemann, Rudolf Konrad 2012. The role of aristolochene synthase in diphosphate activation. Chemical Communications- Royal Society of Chemistry 48 (26) , pp. 3230-3232. 10.1039/c2cc17588f |
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| Faraldos, Juan A., Antonczak, Alicja K., Gonzalez, Veronica, Fullerton, Rebecca, Tippmann, Eric Michael and Allemann, Rudolf Konrad 2011. Probing eudesmane cation−π interactions in catalysis by aristolochene synthase with non-canonical amino acids. Journal of the American Chemical Society 133 (35) , pp. 13906-13909. 10.1021/ja205927u |
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| Faraldos, Juan A., Kariuki, Benson and Coates, Robert M. 2011. 2-Azapinanes: Aza Analogues of the Enantiomeric Pinyl Carbocation Intermediates in Pinene Biosynthesis. Organic Letters 13 (5) , pp. 836-839. 10.1021/ol1027893 |
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| Faraldos, Juan A., Gonzalez, Veronica, Senske, Michael and Allemann, Rudolf Konrad 2011. Templating effects in aristolochene synthase catalysis: elimination versus cyclisation. Organic & Biomolecular Chemistry 9 (20) , pp. 6920-6923. 10.1039/c1ob06184d |
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| Faraldos, Juan A. and Allemann, Rudolf Konrad 2011. Inhibition of (+)-Aristolochene Synthase with Iminium Salts Resembling Eudesmane Cation. Organic Letters 13 (5) , pp. 1202-1205. 10.1021/ol2000843 |
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| Kaspera, Rüdiger, Cape, Jonathan L., Faraldos, Juan A., Ketchum, Raymond E. B. and Croteau, Rodney B. 2010. Synthesis and in vitro evaluation of taxol oxetane ring D precursors. Tetrahedron Letters 51 (15) , pp. 2017-2019. 10.1016/j.tetlet.2010.02.033 |
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| Noel, Joseph P., Dellas, Nikki, Faraldos, Juan A., Zhao, M., Hess, A. Jr., Smentek, L., Coates, Robert M. and O'Maille, Paul E. 2010. Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates. ACS Chemical Biology 5 (4) , pp. 377-392. 10.1021/cb900295g |
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| Faraldos, Juan A., Kariuki, Benson and Allemann, Rudolf Konrad 2010. Intermediacy of Eudesmane Cation during Catalysis by Aristolochene Synthase. Journal of Organic Chemistry 75 (4) , pp. 1119-1125. 10.1021/jo902397v |
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| Faraldos, Juan A., O'Maille, Paul E., Dellas, Nikki, Noel, Joseph P. and Coates, Robert M. 2010. Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate. Journal of the American Chemical Society 132 (12) , pp. 4281-4289. 10.1021/ja909886q |
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| Faraldos, Juan A., Wu, Shuiqin, Chappell, Joe and Coates, Robert M. 2010. Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-2H1]farnesyl diphosphate catalyzed by recombinant patchoulol synthase. Journal of the American Chemical Society 132 (9) , pp. 2998-3008. 10.1021/ja909251r |
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| Hu, Huayou, Faraldos, Juan A. and Coates, Robert M. 2009. Scope and mechanism of intramolecular aziridination of cyclopent-3-enyl-methylamines to 1-azatricyclo[2.2.1.02,6]heptanes with lead tetraacetate. Journal of the American Chemical Society 131 (33) , pp. 11998-12006. 10.1021/ja9044136 |
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| Shishova, Ekaterina Y., Yu, Fanglei, Miller, David James, Faraldos, Juan A., Zhao, Yuxin X., Coates, Robert M., Allemann, Rudolf Konrad, Cane, David E. and Christianson, David W. 2008. X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. Journal of Biological Chemistry 283 (22) , pp. 15431-15439. 10.1074/jbc.M800659200 |
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