Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by All Cardiff Authors

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Number of items: 307.

Appanna, Gautham D, Pembroke, Thomas P I, Miners, Kelly L, Price, David A, Gallimore, Awen M, Ladell, Kristin and Godkin, Andrew J 2019. Rituximab depletion of intrahepatic B cells to control refractory hepatic autoimmune overlap syndrome. QJM: An International Journal of Medicine 112 (10) , pp. 793-795. 10.1093/qjmed/hcz161
file

Thomas, Sharyn, Mohammed, Fiyaz, Reijmers, Rogier M., Woolston, Annemarie, Stauss, Theresa, Kennedy, Alan, Stirling, David, Holler, Angelika, Green, Louisa, Jones, David, Matthews, Katherine K., Price, David A., Chain, Benjamin M., Heemskerk, Mirjam H. M., Morris, Emma C., Willcox, Benjamin E. and Stauss, Hans J. 2019. Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function. Nature Communications 10 , -. 10.1038/s41467-019-12441-w
file

Tauber, C, Schultheiss, M, De Luca, R, Buettner, N, Llewellyn-Lacey, S, Emmerich, F, Zehe, S, Price, D A, Neumann-Haefelin, C, Schmitt-Graeff, A, Hoffman, M and Thimme, R 2019. Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma. Oncotarget 10 (50) , pp. 5194-5206. 10.18632/oncotarget.27146
file

Liu, Jie, Hill, Brenna J, Darko, Sam, Song, Kaimei, Quigley, Máire F, Asher, Tedi E, Morita, Yohei, Greenaway, Hui Y, Venturi, Vanessa, Douek, Daniel C, Davenport, Miles P, Price, David A and Roederer, Mario 2019. The peripheral differentiation of human natural killer T cells. Immunology and Cell Biology 97 (6) , pp. 586-596. 10.1111/imcb.12248
file

Wong, Emily B., Gold, Marielle C., Meermeier, Erin W., Xulu, Bongiwe Z., Khuzwayo, Sharon, Sullivan, Zuri A., Mahyari, Eisa, Rogers, Zoe, Kløverpris, Hénrik, Sharma, Prabhat K., Worley, Aneta H., Lalloo, Umesh, Baijnath, Prinita, Ambaram, Anish, Naidoo, Leon, Suleman, Moosa, Madansein, Rajhmun, McLaren, James E., Ladell, Kristin, Miners, Kelly L., Price, David A., Behar, Samuel M., Nielsen, Morten, Kasprowicz, Victoria O., Leslie, Alasdair, Bishai, William R., Ndung'u, Thumbi and Lewinsohn, David M. 2019. TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology 2 (1) , -. 10.1038/s42003-019-0442-2
file

Kemming, Janine, Reeves, Emma, Nitschke, Katja, Widmeier, Vanessa, Emmerich, Florian, Hermle, Tobias, Gostick, Emma, Walker, Andreas, Timm, Jörg, Price, David A., Hofmann, Maike, Thimme, Robert, James, Edward and Neumann-Haefelin, Christoph 2019. ERAP1 allotypes shape the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection. Journal of Hepatology 70 (6) , pp. 1072-1081. 10.1016/j.jhep.2019.01.034
file

Karimzadeh, Hadi, Kiraithe, Muthamia M., Oberhardt, Valerie, Salimi Alizei, Elahe, Bockmann, Jan, Schulze zur Wiesch, Julian, Budeus, Bettina, Hoffmann, Daniel, Wedemeyer, Heiner, Cornberg, Markus, Krawczyk, Adalbert, Rashidi-Alavijeh, Jassin, Rodríguez-Frías, Francisco, Casillas, Rosario, Buti, Maria, Smedile, Antonina, Alavian, Seyed Moayed, Heinold, Andreas, Emmerich, Florian, Panning, Marcus, Gostick, Emma, Price, David A., Timm, Jörg, Hofmann, Maike, Raziorrouh, Bijan, Thimme, Robert, Protzer, Ulrike, Roggendorf, Michael and Neumann-Haefelin, Christoph 2019. Mutations in hepatitis D virus allow it to escape detection by CD8+ T Cells and evolve at the population level. Gastroenterology 156 (6) , pp. 1820-1833. 10.1053/j.gastro.2019.02.003
file

Schuch, Anita, Salimi Alizei, Elahe, Heim, Kathrin, Wieland, Dominik, Kiraithe, Michael Muthamia, Kemming, Janine, Llewellyn-Lacey, Sian, Sogukpinar, Özlem, Ni, Yi, Urban, Stephan, Zimmermann, Peter, Nassal, Michael, Emmerich, Florian, Price, David A., Bengsch, Bertram, Luxenburger, Hendrik, Neumann-Haefelin, Christoph, Hofmann, Maike and Thimme, Robert 2019. Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load. Gut 68 , pp. 905-915. 10.1136/gutjnl-2018-316641
file

Li, Na, van Unen, Vincent, Abdelaal, Tamim, Guo, Nannan, Kasatskaya, Sofya A., Ladell, Kristin, McLaren, James E., Egorov, Evgeny S., Izraelson, Mark, Chuva de Sousa Lopes, Susana M., Höllt, Thomas, Britanova, Olga V, Eggermont, Jeroen, de Miranda, Noel F. C. C., Chudakov, Dmitriy M., Price, David A., Lelieveldt, Boudewijn P. F. and Koning, Frits 2019. Memory CD4+ T cells are generated in the human fetal intestine. Nature Immunology 20 , pp. 301-312. 10.1038/s41590-018-0294-9
file

Mayassi, Toufic, Ladell, Kristin, Gudjonson, Herman, McLaren, James, Shaw, Dustin G., Tran, Mai T., Rokicka, Jagoda J., Lawrence, Ian, Grenier, Jean-Christophe, van Unen, Vincent, Ciszewski, Cezary, Dimaano, Matthew, Sayegh, Hoda E., Kumar, Vinod, Wijmenga, Cisca, Green, Peter H.R., Gokhale, Ranjana, Jericho, Hilary, Semrad, Carol E., Guandalini, Stefano, Dinner, Aaron R., Kupfer, Sonia S., Reid, Hugh H., Barreiro, Luis B., Rossjohn, Jamie, Price, David A. and Jabri, Bana 2019. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Cell 176 (5) , pp. 967-981. 10.1016/j.cell.2018.12.039
Item availability restricted.
file

McLaren, James, Clement, Mathew, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J., Ladell, Kristin, Price, David A. and Humphreys, Ian R. 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202 (2) , ji1701757. 10.4049/jimmunol.1701757
file

Edwards, Emily S.J., Bier, Julia, Cole, Theresa S., Wong, Melanie, Hsu, Peter, Berglund, Lucinda J., Boztug, Kaan, Lau, Anthony, Gostick, Emma, Price, David A., O'Sullivan, Michael, Meyts, Isabelle, Choo, Sharon, Gray, Paul, Holland, Steven M., Deenick, Elissa K., Uzel, Gulbu and Tangye, Stuart G. 2019. Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity. Journal of Allergy and Clinical Immunology 143 (1) , pp. 276-291. 10.1016/j.jaci.2018.04.030
file

Shimauchi, Takatoshi, Caucheteux, Stephan, Finsterbusch, Katja, Turpin, Jocelyn, Blanchet, Fabien, Ladell, Kristin, Triantafilou, Kathy, Czubala, Magdalena, Tatsuno, Kazuki, Easter, Tammy, Ahmed, Zahra, Bayliss, Rebecca, Hakobyan, Svetlana, Price, David A., Tokura, Yoshiki and Piguet, Vincent 2019. Dendritic cells promote the spread of human T-cell leukemia virus type-1 via bidirectional interactions with CD4 + T-cells. Journal of Investigative Dermatology 139 (1) , pp. 157-166. 10.1016/j.jid.2018.06.188
file

Nicoli, Francesco, Papagno, Laura, Frere, Justin J., Cabral-Piccin, Mariela Pires, Clave, Emmanuel, Gostick, Emma, Toubert, Antoine, Price, David A., Caputo, Antonella and Appay, Victor 2018. Naïve CD8+ T-cells engage a versatile metabolic program upon activation in humans and differ energetically from memory CD8+ T-cells. Frontiers in Immunology 9 , -. 10.3389/fimmu.2018.02736
file

Boelen, Lies, Debebe, Bisrat, Silveira, Marcos, Salam, Arafa, Makinde, Julia, Roberts, Chrissy h., Wang, Edward, Frater, John, Gilmour, Jill, Twigger, Katie, Ladell, Kristin, Miners, Kelly L., Jayaraman, Jyothi, Traherne, James A., Price, David A., Qi, Ying, Martin, Maureen P., Macallan, Derek C., Thio, Chloe L., Astemborski, Jacquie, Kirk, Gregory, Donfield, Sharyne M., Buchbinder, Susan, Khakoo, Salim I., Goedert, James J., Trowsdale, John, Carrington, Mary, Kollnberger, Simon and Asquith, Becca 2018. Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1. Science Immunology 3 (29) , eaao2892. 10.1126/sciimmunol.aao2892
filefile

Pogorelyy, Mikhail V., Fedorova, Alla D., McLaren, James E., Ladell, Kristin, Bagaev, Dmitri V., Eliseev, Alexey V., Mikelov, Artem I., Koneva, Anna E., Zvyagin, Ivan V., Price, David A., Chudakov, Dmitry M. and Shugay, Mikhail 2018. Exploring the pre-immune landscape of antigen-specific T cells. Genome Medicine 10 , 68. 10.1186/s13073-018-0577-7
file

Morabito, Kaitlyn M., Ruckwardt, Tracy J., Bar-Haim, Erez, Nair, Deepika, Moin, Syed M., Redwood, Alec J., Price, David A. and Graham, Barney S. 2018. Memory inflation drives tissue-resident memory CD8+ T cell maintenance in the lung after intranasal vaccination with murine cytomegalovirus. Frontiers in Immunology 9 , 1861. 10.3389/fimmu.2018.01861
file

Powell, Wendy E., Hanna, Stephanie J., Hocter, Claire N., Robinson, Emma, Davies, Joanne, Dunseath, Gareth J., Luzio, Stephen, Farewell, Daniel, Wen, Li, Dayan, Colin M., Price, David A., Ladell, Kristin and Wong, F. Susan 2018. Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes. Diabetologia 61 (8) , pp. 1794-1803. 10.1007/s00125-018-4651-x
file

Costa del Amo, Pedro, Beneytez, Julio Lahoz, Boelen, Lies, Ahmed, Raya, Miners, Kelly L., Zhang, Yan, Roger, Laureline, Jones, Rhiannon E., Marraco, Silvia A. Fuertes, Speiser, Daniel E., Baird, Duncan M., Price, David A., Ladell, Kristin, Macallan, Derek and Asquith, Becca 2018. Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness. PLoS Biology 16 (6) , e2005523. 10.1371/journal.pbio.2005523
file

Buggert, Marcus, Nguyen, Son, Salgado-Montes de Oca, Gonzalo, Bengsch, Bertram, Darko, Samuel, Ransier, Amy, Roberts, Emily R., del Alcazar, Daniel, Brody, Irene Bukh, Vella, Laura A., Beura, Lalit, Wijeyesinghe, Sathi, Herati, Ramin S., Del Rio Estrada, Perla M., Ablanedo-Terrazas, Yuria, Kuri-Cervantes, Leticia, Sada Japp, Alberto, Manne, Sasikanth, Vartanian, Shant, Huffman, Austin, Sandberg, Johan K., Gostick, Emma, Nadolski, Gregory, Silvestri, Guido, Canaday, David H., Price, David A., Petrovas, Constantinos, Su, Laura F., Vahedi, Golnaz, Dori, Yoav, Frank, Ian, Itkin, Maxim G., Wherry, E. John, Deeks, Steven G., Naji, Ali, Reyes-Terán, Gustavo, Masopust, David, Douek, Daniel C. and Betts, Michael R. 2018. Identification and characterization of HIV-specific resident memory CD8 + T cells in human lymphoid tissue. Science Immunology 3 (24) , eaar4526. 10.1126/sciimmunol.aar4526

Martin, Maureen P., Naranbhai, Vivek, Shea, Patrick R., Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L., Carlson, Jonathan M., Wolinsky, Steven M., Goedert, James J., Walker, Bruce D., Segal, Florencia P., Deeks, Steven G., Haas, David W., Migueles, Stephen A., Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A., Lafont, Bernard A., Pymm, Phillip, Saunders, Philippa M., Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P., Rossjohn, Jamie, Brooks, Andrew G. and Carrington, Mary 2018. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation 128 (5) , p. 1903. 10.1172/JCI98463
file

Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S. J., Galloway, Sarah A. E., Laugel, Bruno, Clement, Mathew, Makinde, Julia, Ladell, Kristin, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne, Attaf, Meriem, Lissina, Anya, Ager, Ann, Gallimore, Awen, Rizkallah, Pierre J., Gras, Stephanie, Rossjohn, Jamie, Burrows, Scott R., Cole, David K., Price, David A. and Sewell, Andrew K. 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. The Journal of Clinical Investigation 128 (4) , pp. 1569-1580. 10.1172/JCI91512
file

Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., McLaren, James E., Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A., Van Rhijn, Ildiko, Moody, D. Branch and Rossjohn, Jamie 2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19 , pp. 397-406. 10.1038/s41590-018-0065-7
file

James, Eddie A., Abreu, Joana R. F., McGinty, John W., Odegard, Jared M., Fillié, Yvonne E., Hocter, Claire N., Culina, Slobodan, Ladell, Kristin, Price, David A., Alkanani, Aimon, Rihanek, Marynette, Fitzgerald-Miller, Lisa, Skowera, Ania, Speake, Cate, Gottlieb, Peter, Davidson, Howard W., Wong, F. Susan, Roep, Bart and Mallone, Roberto 2018. Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop. Diabetologia 61 (3) , pp. 658-670. 10.1007/s00125-017-4508-8
file

Culina, Slobodan, Lalanne, Ana Ines, Afonso, Georgia, Cerosaletti, Karen, Pinto, Sheena, Sebastiani, Guido, Kuranda, Klaudia, Nigi, Laura, Eugster, Anne, Østerbye, Thomas, Maugein, Alicia, McLaren, James, Ladell, Kristin, Larger, Etienne, Beressi, Jean-Paul, Lissina, Anna, Appay, Victor, Davidson, Howard W., Buus, Søren, Price, David, Kuhn, Matthias, Bonifacio, Ezio, Battaglia, Manuela, Caillat-Zucman, Sophie, Dotta, Francesco, Scharfmann, Raphael, Kyewski, Bruno and Mallone, Roberto 2018. Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors. Science Immunology 3 (20) , eaao4013. 10.1126/sciimmunol.aao4013
file

Shugay, M., Bagaev, D. V., Zvyagin, I. V., Vroomans, R. M., Crawford, J. C., Dolton, Garry M., Komech, Ekaterina A., Sycheva, Anastasiya L., Koneva, Anna E., Egorov, Evgeniy S., Eliseev, Alexey V., Van Dyk, E., Dash, P., Attaf, Meriem, Ruis, Cristina, Ladell, Kristin Ingrid, McLaren, James E., Matthews, Katherine K., Clemens, Ella B., Douek, Daniel C., Luciani, Fabio, Van Baarle, D., Kedzierska, Katherine, Kesmir, Can, Thomas, Paul G., Price, David, Sewell, Andrew K. and Chudakov, Dimitry M. 2018. VDJdb: a curated database of T-cell receptor sequences with known antigen specificity. Nucleic Acids Research 46 (D1) , D419-D427. 10.1093/nar/gkx760
file

Lissina, Anna, McLaren, James E., Ilander, Mette, Andersson, Emma I., Lewis, Catherine S., Clement, Mathew, Herman, Andrew, Ladell, Kristin, Llewellyn-Lacey, Sian, Miners, Kelly L., Gostick, Emma, Melenhorst, J. Joseph, Barrett, A. John, Price, David A., Mustjoki, Satu and Wooldridge, Linda 2018. Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions. Scientific Reports 8 (1) , 2534. 10.1038/s41598-017-18062-x
file

Reuter, Morgan A., Del Rio Estrada, Perla M., Buggert, Marcus, Petrovas, Constantinos, Ferrando-Martinez, Sara, Nguyen, Son, Sada Japp, Alberto, Ablanedo-Terrazas, Yuria, Rivero-Arrieta, Amaranta, Kuri-Cervantes, Leticia, Gunzelman, Heidi M., Gostick, Emma Gostick, Price, David, Koup, Richard A., Naji, Ali, Canaday, David H., Reyes-Terán, Gustavo and Betts, Michael R. 2017. HIV-specific CD8 + T cells exhibit reduced and differentially regulated Cytolytic activity in Lymphoid tissue. Cell Reports 21 (12) , pp. 3458-3470. 10.1016/j.celrep.2017.11.075
file

Van Braeckel-Budimir, Natalija, Gras, Stephanie, Ladell, Kristin, Josephs, Tracy M., Pewe, Lecia, Urban, Stina L., Miners, Kelly, Farenc, Carine, Price, David, Rossjohn, Jamie and Harty, John T. 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47 (5) , pp. 835-847. 10.1016/j.immuni.2017.10.013
file

Culshaw, Abigail, Ladell, Kristin, Gras, Stephanie, McLaren, James, Miners, Kelly, Farenc, Carine, van den Heuvel, Heleen, Gostick, Emma, Dejnirattisai, Wanwisa, Wangteeraprasert, Apirath, Duangchinda, Thaneeya, Chotiyarnwong, Pojchong, Limpitikul, Wannee, Vasanawathana, Sirijitt, Malasit, Prida, Dong, Tao, Rossjohn, Jamie, Mongkolsapaya, Juthathip, Price, David and Screaton, Gavin R 2017. Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response. Nature Immunology 18 (11) , pp. 1228-1237. 10.1038/ni.3850
filefilefilefilefilefilefilefilefilefilefilefilefilefile

Anguille, Sébastien, Van de Velde, Ann L., Smits, Evelien L., Van Tendeloo, Viggo F., Juliusson, Gunnar, Cools, Nathalie, Nijs, Griet, Stein, Barbara, Lion, Eva, Van Driessche, Ann, Vandenbosch, Irma, Verlinden, Anke, Gadisseur, Alain P., Schroyens, Wilfried A., Muylle, Ludo, Vermeulen, Katrien, Maes, Marie-Berthe, Deiteren, Kathleen, Malfait, Ronald, Gostick, Emma, Lammens, Martin, Couttenye, Marie M., Jorens, Philippe, Goossens, Herman, Price, David, Ladell, Kristin, Oka, Yoshihiro, Fujiki, Fumihiro, Oji, Yusuke, Sugiyama, Haruo and Berneman, Zwi N. 2017. Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia. Blood 130 (15) , pp. 1713-1721. 10.1182/blood-2017-04-780155
file

Zanon, Veronica, Pilipow, Karolina, Scamardella, Eloise, De Paoli, Federica, De Simone, Gabriele, Price, David, Martinez Usatorre, Amaia, Romero, Pedro, Mavilio, Domenico, Roberto, Alessandra and Lugli, Enrico 2017. Curtailed T-cell activation curbs effector differentiation and generates CD8+ T cells with a naturally-occurring memory stem cell phenotype. European Journal of Immunology 47 (9) , pp. 1468-1476. 10.1002/eji.201646732
file

Chen, Hung-Chang, Joalland, Noémie, Bridgeman, John S, Alchami, Fouad S, Jarry, Ulrich, Khan, Mohd Wajid A, Piggott, Luke, Shanneik, Yasmin, Li, Jianqiang, Herold, Marco J, Herrmann, Thomas, Price, David A., Gallimore, Awen M., Clarkson, Richard W., Scotet, Emmanuel, Moser, Bernhard and Eberl, Matthias 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7) , pp. 620-629. 10.1038/icb.2017.21
file

Gutjahr, Alice, Papagno, Laura, Nicoli, Francesco, Lamoureux, Alain, Vernejoul, Fabienne, Lioux, Thierry, Gostick, Emma, Price, David, Tiraby, Gérard, Perouzel, Eric, Appay, Victor, Verrier, Bernard and Paul, Stéphane 2017. Cutting edge: a dual TLR2 and TLR7 ligand induces highly potent humoral and cell-mediated immune responses. Journal of Immunology 198 (11) , pp. 4205-4209. 10.4049/jimmunol.1602131

Murrell, Isa, Bedford, Carmen, Ladell, Kristin Ingrid, Miners, Kelly Louise, Price, David, Tomasec, Peter, Wilkinson, Gavin William Grahame and Stanton, Richard James 2017. The pentameric complex drives immunologically covert cell -cell transmission of wild-type human cytomegalovirus. Proceedings of the National Academy of Sciences of the United States of America 114 (23) , pp. 6104-6109. 10.1073/pnas.1704809114
file

Pymm, Phillip, Illing, Patricia T, Ramarathinam, Sri H, O'Connor, Geraldine M, Hughes, Victoria A, Hitchen, Corinne, Price, David, Ho, Bosco K, McVicar, Daniel W, Brooks, Andrew G, Purcell, Anthony W, Rossjohn, Jamie and Vivian, Julian P 2017. MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nature Structural & Molecular Biology 24 (4) , pp. 387-394. 10.1038/nsmb.3381
file

Davey, Martin S., Willcox, Carrie R., Joyce, Stephen P., Ladell, Kristin, Kasatskaya, Sofya A., McLaren, James E., Hunter, Stuart, Salim, Mahboob, Mohammed, Fiyaz, Price, David A., Chudakov, Dmitriy M. and Willcox, Benjamin E. 2017. Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance. Nature Communications 8 , 14760. 10.1038/ncomms14760
file

Morabito, K M, Ruckwardt, T R, Redwood, A J, Moin, S M, Price, David and Graham, B S 2017. Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung. Mucosal Immunology 10 (2) , pp. 545-554. 10.1038/mi.2016.48
file

Smith, Corey, Lee, Victor, Schuessler, Andrea, Beagley, Leone, Rehan, Sweera, Tsang, Janice, Li, Vivian, Tiu, Randal, Smith, David, A. Neller, Michelle, Matthews, Katherine K., Gostick, Emma, Price, David, Burrows, Jacqueline, Boyle, Glen M., Chua, Daniel, Panizza, Benedict, Porceddu, Sandro V., Nicholls, John, Kwong, Dora and Khanna, Rajiv 2017. Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response. OncoImmunology 6 (2) , e1273311. 10.1080/2162402X.2016.1273311
file

Dockree, Tamsin, Holland, Christopher J., Clement, Mathew, Ladell, Kristin Ingrid, McLaren, James Edward, Van Den Berg, Hugo A., Gostick, Emma, Llewellyn-Lacey, Sian, Man, Stephen Tzekwung, Bailey, Mick, Burrows, Scott, Price, David and Wooldridge, Linda 2017. CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold. Immunology and Cell Biology 95 (1) , pp. 68-76. 10.1038/icb.2016.85
file

Abolhassani, Hassan, Edwards, Emily S.J., Ikinciogullari, Aydan, Jing, Huie, Borte, Stephan, Buggert, Marcus, Du, Likun, Matsuda-Lennikov, Mami, Romano, Rosa, Caridha, Rozina, Bade, Sangeeta, Zhang, Yu, Frederiksen, Juliet, Fang, Mingyan, Bal, Sevgi Kostel, Haskologlu, Sule, Dogu, Figen, Tacyildiz, Nurdan, Matthews, Helen F., McElwee, Joshua J., Gostick, Emma, Price, David, Palendira, Umaimainthan, Aghamohammadi, Asghar, Boisson, Bertrand, Rezaei, Nima, Karlsson, Annika C., Lenardo, Michael J., Casanova, Jean-Laurent, Hammarström, Lennart, Tangye, Stuart G., Su, Helen C. and Pan-Hammarström, Qiang 2017. Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency. Journal of Experimental Medicine 214 (1) , p. 91. 10.1084/jem.20160849
file

Ahmed, Raya, Roger, Laureline, Costa del Amo, Pedro, Miners, Kelly Louise, Jones, Rhiannon E., Boelen, Lies, Fali, Tinhinane, Elemans, Marjet, Zhang, Yan, Appay, Victor, Baird, Duncan Martin, Asquith, Becca, Price, David, Macallan, Derek C. and Ladell, Kristin Ingrid 2016. Human stem cell-like memory T cells are maintained in a state of dynamic flux. Cell Reports 17 (11) , pp. 2811-2818. 10.1016/j.celrep.2016.11.037
file

Clement, Mathew, Pearson, James, Gras, Stephanie, Van den berg, Hugo, Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark, Dockree, Tamsin, McLaren, James, Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil, Burrows, Scott, Price, David, Wong, Florence, Peakman, Mark, Skowera, Ania and Wooldridge, Linda 2016. Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies. Scientific Reports 6 , 35332. 10.1038/srep35332
file

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Bridgeman, John S, Cohnen, André, Benzing, Carola, Gao, Yijun, Crowther, Michael D, Tungatt, Katie, Dolton, Garry, Sewell, Andrew, Price, David A, Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jérémie, Rossjohn, Jamie and Gaus, Katharina 2016. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (37) , E5454-E5463. 10.1073/pnas.1607436113
file

Watson, H. Angharad, Dolton, Garry Michael, Ohme, Julia, Ladell, Kristin Ingrid, Vigar, Miriam, Wehenkel, Sophie, Hindley, James, Mohammed, Rebar, Miners, Kelly, Luckwell, Rhys A, Price, David, Matthews, R James and Ager, Ann 2016. Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1. Immunology and Cell Biology 94 , pp. 802-808. 10.1038/icb.2016.45
file

Pearson, James A., Thayer, Terri, McLaren, James Edward, Ladell, Kristin, De Leenheer, Evy, Phillips, Amy, Davies, Joanne, Kakabadse, Dimitri, Miners, Kelly Louise, Morgan, Peter, Wen, Li, Price, David and Wong, Florence Susan 2016. Proinsulin expression shapes the TCR repertoire but fails to control the development of low-avidity insulin-reactive CD8+T cells. Diabetes 65 (6) , pp. 1679-1689. 10.2337/db15-1498
file

de Paula Alves Sousa, Alessandra, Johnson, Kory R., Nicholas, Richard, Darko, Sam, Price, David, Douek, Daniel C., Jacobson, Steven and Muraro, Paolo A. 2016. Intrathecal T-cell clonal expansions in patients with multiple sclerosis. Annals of Clinical and Translational Neurology 3 (6) , pp. 422-433. 10.1002/acn3.310
file

Caucheteux, Stephan M., Mitchell, John P., Ivory, Matthew O., Hirosue, Sachiko, Hakobyan, Svetlana, Dolton, Garry, Ladell, Kristin Ingrid, Miners, Kelly Louise, Price, David, Kan-Mitchell, June, Sewell, Andrew K., Nestle, Frank, Moris, Arnaud, Karoo, Richard O., Birchall, James Caradoc, Swartz, Melody A., Hubbel, Jeffrey A., Blanchet, Fabien P. and Piguet, Vincent 2016. Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. Journal of Investigative Dermatology 136 (6) , pp. 1172-1181. 10.1016/j.jid.2016.01.033
file

Vinton, Carol, Wu, Fan, Rossjohn, Jamie, Matsuda, Kenta, McCluskey, James, Hirsch, Vanessa, Price, David, Brenchley, Jason M. and Silvestri, G. 2016. Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques. Journal of Virology 90 (9) , pp. 4520-4529. 10.1128/JVI.02876-15
file

Valkenburg, Sophie A., Josephs, Tracy M., Clemens, E. Bridie, Grant, Emma J., Nguyen, Thi H. O., Wang, George C., Price, David, Miller, Adrian, Tong, Steven Y. C., Thomas, Paul G., Doherty, Peter C., Rossjohn, Jamie, Gras, Stephanie and Kedzierska, Katherine 2016. Molecular basis for universal HLA-A*0201 - restricted CD8+ T-cell immunity against influenza viruses. Proceedings of the National Academy of Sciences of the United States of America 113 (16) , pp. 4440-4445. 10.1073/pnas.1603106113

Du, V. Y., Bansal, A., Carlson, J., Salazar-Gonzalez, J. F., Salazar, M. G., Ladell, Kristin Ingrid, Gras, S., Josephs, T. M., Heath, S. L., Price, David, Rossjohn, Jamie, Hunter, E. and Goepfert, P. A. 2016. HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection. The Journal of Immunology 196 (8) , pp. 3276-3286. 10.4049/jimmunol.1502411

Saunders, Philippa M., Pymm, Phillip, Pietra, Gabriella, Hughes, Victoria A., Hitchen, Corinne, O?Connor, Geraldine M., Loiacono, Fabrizio, Widjaja, Jacqueline, Price, David, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, McVicar, Daniel W., Rossjohn, Jamie, Brooks, Andrew G. and Vivian, Julian P. 2016. Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition. Journal of Experimental Medicine 213 (5) , pp. 791-807. 10.1084/jem.20152023
file

Ridley, Anna, Hatano, Hiroko, Wong-Baeza, Isabel, Shaw, Jacqueline, Matthews, Katherine K., Al-Mossawi, Hussein, Ladell, Kristin Ingrid, Price, David, Bowness, Paul and Kollnberger, Simon 2016. Activation-induced killer cell immunoglobulin-like receptor 3DL2 binding to HLA-B27 licenses pathogenic T cell differentiation in spondyloarthritis. Arthritis and Rheumatology 68 (4) , pp. 901-914. 10.1002/art.39515
file

Szomolay, Barbara, Liu, Jie, Brown, Paul E, Miles, John J, Clement, Mathew, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea, Sewell, Andrew, Burrows, Scott R, Roederer, Mario, Price, David, Wooldridge, Linda and van den Berg, Hugo A 2016. Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors. Immunology and Cell Biology 94 (6) , pp. 573-582. 10.1038/icb.2016.12
file

Jones, Kimberley, Wockner, Leesa, Brennan, Rebekah M., Keane, Colm, Chattopadhyay, Pratip K., Roederer, Mario, Price, David, Cole, David, Hassan, Brekhna, Beck, Konrad, Gottlieb, David, Ritchie, David S., Seymour, John F., Vari, Frank, Crooks, Pauline, Burrows, Scott R. and Gandhi, Maher K. 2016. The impact of HLA-class I and EBV-latency-II antigen-specific CD8+T-cells on the pathogenesis of EBV+ Hodgkin Lymphoma. Clinical and Experimental Immunology 183 (2) , pp. 206-220. 10.1111/cei.12716
filefile

Briceño, Olivia, Lissina, Anna, Wanke, Kerstin, Afonso, Georgia, von Braun, Amrei, Ragon, Kristanto, Miquel, Tiphaine, Gostick, Emma, Papagno, Laura, Stiasny, Karin, Price, David, Mallone, Roberto, Sauce, Delphine, Karrer, Urs and Appay, Victor 2016. Reduced naïve CD8+T-cell priming efficacy in elderly adults. Aging Cell 15 (1) , pp. 14-21. 10.1111/acel.12384
file

Lissina, Anna, Briceño, Olivia, Afonso, Georgia, Larsen, Martin, Gostick, Emma, Price, David, Mallone, Roberto and Appay, Victor 2016. Priming of qualitatively superior human effector CD8+ T cells using TLR8 ligand combined with FLT3 ligand. The Journal of Immunology 196 (1) , pp. 256-263. 10.4049/jimmunol.1501140
Item availability restricted.
file

Holland, C. J., Dolton, Garry Michael, Scurr, Martin John, Ladell, Kristin Ingrid, Schauenburg, Andrea J. A., Miners, Kelly Louise, Madura, F., Sewell, Andrew K., Price, David, Cole, David and Godkin, Andrew James 2015. Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers. The Journal of Immunology 195 (12) , pp. 5827-5836. 10.4049/jimmunol.1402787
file

Townsley, Elizabeth, O'Connor, Geraldine, Cosgrove, Cormac, Woda, Marcia, Co, Mary, Thomas, Stephen J., Kalayanarooj, Siripen, Yoon, In-Kyu, Nisalak, Ananda, Srikiatkhachorn, Anon, Green, Sharone, Stephens, Henry A.F., Gostick, Emma, Price, David, Carrington, Mary, Alter, Galit, McVicar, Daniel W., Rothman, Alan L. and Matthew, Anuja 2015. Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells. Clinical & Experimental Immunology 183 (3) , pp. 419-430. 10.1111/cei.12722
file

Pombo, Carolina, Wherry, E. John, Gostick, Emma, Price, David and Betts, Michael R. 2015. Elevated expression of CD160 and 2B4 defines a cytolytic HIV-specific CD8+T-cell population in elite controllers. Journal of Infectious Diseases 212 (9) , pp. 1376-1386. 10.1093/infdis/jiv226

Ladell, Kristin Ingrid, Hazenberg, M. D., Fitch, M., Emson, C., McEvoy-Hein Asgarian, B. K., Mold, J. E., Miller, C., Busch, R., Price, David, Hellerstein, M. K. and McCune, J. M. 2015. Continuous antigenic stimulation of DO11.10 TCR transgenic mice in the presence or absence of IL-1: possible implications for mechanisms of T cell depletion in HIV disease. The Journal of Immunology 195 (9) , pp. 4096-4105. 10.4049/jimmunol.1500799

Beringer, Dennis X., Kleijwegt, Fleur S., Wiede, Florian, van der Slik, Arno R., Loh, Khai Lee, Petersen, Jan, Dudek, Nadine L., Duinkerken, Gaby, Laban, Sandra, Joosten, Antoinette, Vivian, Julian P., Chen, Zhenjun, Uldrich, Adam P., Godfrey, Dale I., McCluskey, James, Price, David, Radford, Kristen J., Purcell, Anthony W., Nikolic, Tatjana, Reid, Hugh H., Tiganis, Tony, Roep, Bart O. and Rossjohn, Jamie 2015. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nature Immunology 16 (11) , pp. 1153-1161. 10.1038/ni.3271
file

Mohns, Mariel S., Greene, Justin M., Cain, Brian T., Pham, Ngoc H., Gostick, Emma, Price, David, O'Connor, David H. and Silvestri, G. 2015. Expansion of Simian Immunodeficiency Virus (SIV)-specific CD8 T cell lines from SIV-naive Mauritian cynomolgus macaques for adoptive transfer. Journal of Virology 89 (19) , pp. 9748-9757. 10.1128/JVI.00993-15

Liuzzi, Anna Rita, McLaren, James Edward, Price, David and Eberl, Matthias 2015. Early innate responses to pathogens: pattern recognition by unconventional human T-cells. Current Opinion in Immunology 36 , pp. 31-37. 10.1016/j.coi.2015.06.002
file

Colbeck, Emily, Hindley, James P., Smart, Kathryn, Jones, Emma, Bloom, Anja, Bridgeman, Hayley, McPherson, Rhoanne C., Turner, Darryl G., Ladell, Kristin Ingrid, Price, David, O'Connor, Richard A., Anderton, Stephen M., Godkin, Andrew James and Gallimore, Awen Myfanwy 2015. Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors. Oncotarget 6 (28) , pp. 24649-24659. 10.18632/oncotarget.5584
file

Neller, Michelle A., Ladell, Kristin Ingrid, McLaren, James Edward, Matthews, Katherine K., Gostick, Emma, Pentier, Johanne, Dolton, Garry Michael, Schauenburg, Andrea J. A., Koning, Dan, Fontaine Costa, Ana Isabel C. A., Watkins, Thomas S., Venturi, Vanessa, Smith, Corey, Khanna, Rajiv, Miners, Kelly Louise, Clement, Mathew, Wooldridge, Linda, Cole, David, van Baarle, Debbie, Sewell, Andrew K., Burrows, Scott R., Price, David and Miles, John James 2015. Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics. Immunology and Cell Biology 93 , pp. 625-633. 10.1038/icb.2015.17
file

Schmied, Sabine, Gostick, Emma, Price, David, Abken, Hinrich, Assenmacher, Mario and Richter, Anne 2015. Analysis of the functional WT1-specific T-cell repertoire in healthy donors reveals a discrepancy between CD4+and CD8+memory formation. Immunology 145 (4) , pp. 558-569. 10.1111/imm.12472
file

Petersen, J., van Bergen, J., Loh, K. L., Kooy-Winkelaar, Y., Beringer, D. X., Thompson, A., Bakker, S. F., Mulder, C. J. J., Ladell, Kristin, McLaren, James Edward, Price, David, Rossjohn, Jamie, Reid, H. H. and Koning, F. 2015. Determinants of gliadin-specific T cell selection in celiac disease. The Journal of Immunology 194 (12) , pp. 6112-6122. 10.4049/jimmunol.1500161

Kloverpris, H. N., McGregor, R., McLaren, James Edward, Ladell, Kristin, Harndahl, M., Stryhn, A., Carlson, J. M., Koofhethile, C., Gerritsen, B., Ke mir, C., Chen, F., Riddell, L., Luzzi, G., Leslie, A., Walker, B. D., Ndung'u, T., Buus, S., Price, David and Goulder, P. J. 2015. CD8+ TCR bias and immunodominance in HIV-1 infection. The Journal of Immunology 194 (11) , pp. 5329-5345. 10.4049/jimmunol.1400854

Motozono, Chihiro, Bridgeman, John S., Price, David, Sewell, Andrew K. and Ueno, T. 2015. Clonotypically similar hybrid ab T cell receptors can exhibit markedly different surface expression, antigen specificity and cross-reactivity. Clinical and Experimental Immunology 180 (3) , pp. 560-570. 10.1111/cei.12610
file

O'Connor, Geraldine M., Vivian, Julian P., Gostick, Emma, Pymm, Phillip, Lafont, Bernard A. P., Price, David, Rossjohn, Jamie, Brooks, Andrew G., McVicar, Daniel W. and Kirchhoff, F. 2015. Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1. Journal of Virology 89 (10) , pp. 5213-5221. 10.1128/JVI.03586-14
file

Roberto, A., Castagna, L., Zanon, V., Bramanti, S., Crocchiolo, R., McLaren, James Edward, Gandolfi, S., Tentorio, P., Sarina, B., Timofeeva, I., Santoro, A., Carlo-Stella, C., Bruno, B., Carniti, C., Corradini, P., Gostick, Emma, Ladell, Kristin Ingrid, Price, David, Roederer, M., Mavilio, D. and Lugli, E. 2015. Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation. Blood 125 (18) , pp. 2855-2864. 10.1182/blood-2014-11-608406

Quinn, Kylie M., Zak, Daniel E., Costa, Andreia, Yamamoto, Ayako, Kastenmuller, Kathrin, Hill, Brenna J., Lynn, Geoffrey M., Darrah, Patricia A., Lindsay, Ross W.B., Wang, Lingshu, Cheng, Cheng, Nicosia, Alfredo, Folgori, Antonella, Colloca, Stefano, Cortese, Riccardo, Gostick, Emma, Price, David, Gall, Jason G.D., Roederer, Mario, Aderem, Alan and Seder, Robert A. 2015. Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling. The Journal of Clinical Investigation 125 (3) , pp. 1129-1146. 10.1172/JCI78280
file

Skowera, Ania, Ladell, Kristin Ingrid, McLaren, James Edward, Dolton, Garry Michael, Matthews, Katherine K., Gostick, Emma, Kronenberg-Versteeg, Deborah, Eichmann, Martin, Knight, Robin R., Heck, Susanne, Powrie, Jake, Bingley, Polly J., Dayan, Colin Mark, Miles, John J., Sewell, Andrew K., Price, David and Peakman, Mark 2015. β-Cell-specific CD8 T Cell phenotype in Type 1 diabetes reflects chronic autoantigen exposure. Diabetes 64 (3) , pp. 916-925. 10.2337/db14-0332
file

Parkinson, Nicholas J., Roddis, Matthew, Ferneyhough, Ben, Zhang, Gang, Marsden, Adam J., Maslau, Siarhei, Sanchez-Pearson, Yasmin, Barthlott, Thomas, Humphreys, Isla, Ladell, Kristin Ingrid, Price, David, Ponting, Chris P., Hollander, Georg and Fischer, Michael D. 2015. Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes. Genome Research 25 (2) , pp. 226-234. 10.1101/gr.179770.114
file

Costa, Ana I., Koning, Dan, Ladell, Kristin, McLaren, James Edward, Grady, Bart P. X., Schellens, Ingrid M. M., van Ham, Petra, Nijhuis, Monique, Borghans, José A. M., Kesmir, Can, Price, David, van Baarle, Debbie and Silvestri, G. 2015. Complex T-cell receptor repertoire dynamics underlie the CD8+T-cell response to HIV-1. Journal of Virology 89 (1) , pp. 110-119. 10.1128/JVI.01765-14
file

Nitschke, Katja, Flecken, Tobias, Schmidt, Julia, Gostick, Emma, Marget, Matthias, Neumann-Haefelin, Christoph, Blum, Hubert E., Price, David, Thimme, Robert and Diamond, M. S. 2015. Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+T cells in chronic infection. Journal of Virology 89 (1) , pp. 25-34. 10.1128/JVI.02242-14
file

Collins, Paul J., Liao, Chia-Te, Price, David and Moser, Bernhard 2014. Improving our understanding of CXCL14, one of the few remaining unknowns in chemokine biology [Abstract]. Immunology 143 (S2) , p. 85. 10.1111/imm.12406

Pearson, James, Thayer, T. C., McLaren, James Edward, Miners, Kelly Louise, Ladell, Kristin Ingrid, Price, David and Wong, Florence Susan 2014. Analysis of the repertoire of insulin-reactive CD8(+) T cells [Abstract]. Immunology 143 (S2) , p. 152. 10.1111/imm.12406

Willis, Gareth R., Connolly, Katherine, Ladell, Kristin Ingrid, Davies, Thomas S., Guschina, Irina, Ramji, Dipak, Miners, Kelly Louise, Price, David, Clayton, Aled, James, Philip Eurig and Rees, Dafydd Aled 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12) , pp. 2756-2769. 10.1093/humrep/deu281

Hill, Brenna J., Darrah, Patricia A., Ende, Zachary, Ambrozak, David R., Quinn, Kylie M., Darko, Sam, Gostick, Emma, Wooldridge, Linda, van den Berg, Hugo A., Venturi, Vanessa, Larsen, Martin, Davenport, Miles P., Seder, Robert A., Price, David and Douek, Daniel C. 2014. Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T Cell populations. The Journal of Immunology 193 (11) , pp. 5626-5636. 10.4049/jimmunol.1401017

Bengsch, Bertram, Ladell, Kristin Ingrid, Martin, Bianca, McLaren, James Edward, Nitschke, Katja, Neumann-Haefelin, Christoph, Price, David and Thimme, Robert 2014. Identification of a TSCM phenotype HCV-specific CD8+T cell response with superior functionality in chronic HCV infection [Abstract]. Hepatology 60 , 1071A-1072A.

Connolly, Katherine, Willis, Gareth, Datta, Dev B.N., Ellins, Elizabeth, Ladell, Kristin, Price, David, Guschina, Irina, Rees, Dafydd Aled and James, Philip 2014. Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. Journal of Lipid Research 55 , pp. 2064-2072. 10.1194/jlr.M049726
file

Taylor, Graham S., Jia, Hui, Harrington, Kevin, Lee, Lip Wai, Turner, James, Ladell, Kristin, Price, David, Tanday, Manjit, Matthews, Jen, Roberts, Claudia, Edwards, Ceri, McGuigan, Lesley, Hartley, Andrew, Wilson, Steve, Hui, Edwin P., Chan, Anthony T.C., Rickinson, Alan B. and Steven, Neil M. 2014. A recombinant modified vaccinia Ankara vaccine encoding Epstein-Barr virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer. Clinical Cancer Research 20 (19) , pp. 5009-5022. 10.1158/1078-0432.CCR-14-1122-T
file

Kløverpris, Henrik N., McGregor, Reuben, McLaren, James Edward, Ladell, Kristin Ingrid, Stryhn, Anette, Koofhethile, Catherine, Brener, Jacqui, Chen, Fabian, Riddell, Lynn, Graziano, Luzzi, Klenerman, Paul, Leslie, Alasdair, Buus, Søren, Price, David and Goulder, Philip 2014. Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load. AIDS 28 (14) , pp. 2007-2021. 10.1097/QAD.0000000000000362
file

Gold, M. C., McLaren, James Edward, Reistetter, J. A., Smyk-Pearson, S., Ladell, Kristin, Swarbrick, G. M., Yu, Y. Y. L., Hansen, T. H., Lund, O., Nielsen, M., Gerritsen, B., Kesmir, C., Miles, John James, Lewinsohn, D. A., Price, David and Lewinsohn, D. M. 2014. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. Journal of Experimental Medicine 211 (8) , pp. 1601-1610. 10.1084/jem.20140507
file

Dolton, Garry Michael, Lissina, A., Skowera, A., Ladell, Kristin Ingrid, Tungatt, Katie, Jones, Emma, Kronenberg-Versteeg, D., Akpovwa, Hephzibah, Pentier, Johanne, Holland, C. J., Godkin, Andrew James, Cole, David, Neller, M. A., Miles, John James, Price, David, Peakman, M. and Sewell, Andrew K. 2014. Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells. Clinical and Experimental Immunology 177 (1) , pp. 47-63. 10.1111/cei.12339
file

Laydon, Daniel J., Melamed, Anat, Sim, Aaron, Gillet, Nicolas A., Sim, Kathleen, Darko, Sam, Kroll, J. Simon, Douek, Daniel C., Price, David, Bangham, Charles R. M. and Asquith, Becca 2014. Quantification of HTLV-1 clonality and TCR diversity. PLoS Computational Biology 10 (6) , e1003646. 10.1371/journal.pcbi.1003646
file

Ondondo, Beatrice, Jones, Emma, Hindley, James, Cutting, Scott, Smart, Kathryn, Bridgeman, Hayley, Matthews, Katherine K., Ladell, Kristin Ingrid, Price, David, Jackson, David G., Godkin, Andrew James, Ager, Ann and Gallimore, Awen Myfanwy 2014. Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cellsviablood vessels and lymphatics. International Journal of Cancer 134 (9) , pp. 2156-2167. 10.1002/ijc.28556
file

Flecken, Tobias, Schmidt, Nathalie, Hild, Sandra, Gostick, Emma, Drognitz, Oliver, Zeiser, Robert, Schemmer, Peter, Bruns, Helge, Eiermann, Thomas, Price, David, Blum, Hubert E., Neumann-Haefelin, Christoph and Thimme, Robert 2014. Immunodominance and functional alterations of tumor-associated antigen-specific CD8+T-cell responses in hepatocellular carcinoma. Hepatology 59 (4) , pp. 1415-1426. 10.1002/hep.26731
file

O'Connor, G. M., Vivian, J. P., Widjaja, J. M., Bridgeman, John S., Gostick, Emma, Lafont, B. A. P., Anderson, S. K., Price, David, Brooks, A. G., Rossjohn, Jamie and McVicar, D. W. 2014. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. The Journal of Immunology 192 (6) , pp. 2875-2884. 10.4049/jimmunol.1303142
file

Melamed, Anat, Witkover, Aviva D., Laydon, Daniel J., Brown, Rachael, Ladell, Kristin, Miners, Kelly, Rowan, Aileen G., Gormley, Niall, Price, David, Taylor, Graham P., Murphy, Edward L. and Bangham, Charles R. M. 2014. Clonality of HTLV-2 in natural infection. PLoS Pathogens 10 (3) , e1004006. 10.1371/journal.ppat.1004006
file

Lissina, Anna, Fastenackels, Solène, Inglesias, Maria C., Ladell, Kristin, McLaren, James, Briceño, Olivia, Gostick, Emma, Papagno, Laura, Autran, Brigitte, Sauce, Delphine, Price, David, Saez-Cirion, Asier and Appay, Victor 2014. The link between CD8+ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate. AIDS 28 (4) , pp. 477-486. 10.1097/QAD.0000000000000175

Bridgeman, John S., Ladell, Kristin Ingrid, Sheard, V. E., Miners, Kelly Louise, Hawkins, R. E., Price, David and Gilham, D. E. 2014. CD3ζ-based chimeric antigen receptors mediate T cell activation viacis- andtrans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy. Clinical and Experimental Immunology 175 (2) , pp. 258-267. 10.1111/cei.12216
file

Scurr, Martin John, Ladell, Kristin Ingrid, Besneux, Matthieu, Christian, Adam, Hockey, T., Smart, Kathryn, Bridgeman, Hayley, Hargest, Rachel, Phillips, S., Davies, M., Price, David, Gallimore, Awen Myfanwy and Godkin, Andrew James 2013. Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3- T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells. Mucosal Immunology n/a 10.1038/mi.2013.62
file

van den Berg, Hugo A., Ladell, Kristin, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew, Cole, David, Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Bridgeman, John S. and Price, David 2013. Cellular-level versus receptor-level response threshold hierarchies in T-cell activation. Frontiers in Immunology 4 , 250. 10.3389/fimmu.2013.00250
file

Harris, M., Burns, C., Becker, E., Braasch, A., Gostick, Emma, Johnson, R., Broman, K., Price, David, Friedrich, T. and O'Connor, S. 2013. Acute-Phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus. Journal of Virology 87 (16) , pp. 9353-9364. 10.1128/JVI.00909-13
file

Roux, Antoine, Mourin, Gisèle, Fastenackels, Solène, Almeida, Jorge R., Iglesias, Maria Candela, Boyd, Anders, Gostick, Emma, Larsen, Martin, Price, David, Sacre, Karim, Douek, Daniel C., Autran, Brigitte, Picard, Clément, Miranda, Sandra de, Sauce, Delphine, Stern, Marc and Appay, Victor 2013. CMV driven CD8+ T-cell activation is associated with acute rejection in lung transplantation. Clinical Immunology 148 (1) , pp. 16-26. 10.1016/j.clim.2013.03.012

Casazza, J., Bowman, K., Adzaku, S., Smith, E., Enama, M., Bailer, R., Price, David, Gostick, E., Gordon, I., Ambrozak, D., Nason, M., Roederer, M., Andrews, C., Maldarelli, F., Wiegand, A., Kearney, M., Persaud, D., Ziemniak, C., Gottardo, R., Ledgerwood, J., Graham, B. and Koup, R. 2013. Therapeutic vaccination expands and improves the function of the HIV-specific memory T-Cell repertoire. International Journal of Infectious Diseases 207 (12) , pp. 1829-1840. 10.1093/infdis/jit098

Liu, Y., Miles, John James, Neller, M., Gostick, E., Price, David, Purcell, A., McCluskey, J., Burrows, S., Rossjohn, Jamie and Gras, S. 2013. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. Journal of Biological Chemistry 288 (22) , pp. 15442-15454. 10.1074/jbc.M112.447185
file

Motozono, Chihiro, Miles, John J., Hasan, Zafrul, Gatanaga, Hiroyuki, Meribe, Stanley C., Price, David, Oka, Shinichi, Sewell, Andrew K. and Ueno, Takamasa 2013. CD8+ T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope. PLoS ONE 8 (6) , e66152. 10.1371/journal.pone.0066152
file

Budimir, Natalija, de Haan, Aalzen, Meijerhof, Tjarko, Waijer, Simke, Boon, Louis, Gostick, Emma, Price, David, Wilschut, Jan and Huckriede, Anke 2013. Critical role of TLR7 signaling in the priming of cross-protective Cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine. PLoS ONE 8 (5) , e63163. 10.1371/journal.pone.0063163
file

Ladell, Kristin Ingrid, Hashimoto, Masao, Iglesias, Maria Candela, Wilmann, Pascal G., McLaren, James Edward, Gras, Stéphanie, Chikata, Takayuki, Kuse, Nozomi, Fastenackels, Solène, Gostick, Emma, Bridgeman, John S., Venturi, Vanessa, Arkoub, Zaïna Aït, Agut, Henri, van Bockel, David J., Almeida, Jorge R., Douek, Daniel C., Meyer, Laurence, Venet, Alain, Takiguchi, Masafumi, Rossjohn, Jamie, Price, David and Appay, Victor 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38 (3) , pp. 425-436. 10.1016/j.immuni.2012.11.021

Quinn, K. M., Da Costa, A., Yamamoto, A., Berry, D., Lindsay, R. W. B., Darrah, P. A., Wang, L., Cheng, C., Kong, W.-P., Gall, J. G. D., Nicosia, A., Folgori, A., Colloca, S., Cortese, R., Gostick, Emma, Price, David, Gomez, C. E., Esteban, M., Wyatt, L. S., Moss, B., Morgan, C., Roederer, M., Bailer, R. T., Nabel, G. J., Koup, R. A. and Seder, R. A. 2013. Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization. The Journal of Immunology 190 (6) , pp. 2720-2735. 10.4049/jimmunol.1202861

Lugli, Enrico, Dominguez, Maria H., Gattinoni, Luca, Chattopadhyay, Pratip K., Bolton, Diane L., Song, Kaimei, Klatt, Nichole R., Brenchley, Jason M., Vaccari, Monica, Gostick, Emma, Price, David, Waldmann, Thomas A., Restifo, Nicholas P., Franchini, Genoveffa and Roederer, Mario 2013. Superior T memory stem cell persistence supports long-lived T cell memory. The Journal of Clinical Investigation 123 (2) , pp. 594-599. 10.1172/JCI66327
file

Chattopadhyay, P., Chelimo, K., Embury, P., Mulama, D., Sumba, P., Gostick, Emma, Ladell, Kristin Ingrid, Brodie, T., Vulule, J., Roederer, M., Moormann, A. and Price, David 2013. Holoendemic malaria exposure is associated with altered epstein-barr virus-specific CD8+ T-cell differentiation. Journal of Virology 87 (3) , pp. 1779-1788. 10.1128/JVI.02158-12
file

Greenaway, Hui Yee, Ng, Benedict, Price, David, Douek, Daniel C., Davenport, Miles P. and Venturi, Vanessa 2013. NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination. Immunobiology 218 (2) , pp. 213-224. 10.1016/j.imbio.2012.04.003

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David, Burrows, Scott R., Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Koning, D., Costa, A. I., Hoof, I., Miles, John James, Nanlohy, N. M., Ladell, Kristin Ingrid, Matthews, Katherine K., Venturi, V., Schellens, I. M. M., Borghans, J. A. M., Kesmir, C., Price, David and van Baarle, D. 2013. CD8+ TCR repertoire formation is guided primarily by the peptide component of the antigenic complex. The Journal of Immunology 190 (3) , pp. 931-939. 10.4049/jimmunol.1202466

Iglesias, Maria Candela, Briceno, Olivia, Gostick, Emma, Moris, Arnaud, Meaudre, Céline, Price, David, Ungeheuer, Marie-Noëlle, Saez-Cirion, Asier, Mallone, Roberto and Appay, Victor 2013. Immunodominance of HLA-B27-restricted HIV KK10-specific CD8+ T-cells is not related to naïve precursor frequency [Letter]. Immunology Letters 149 (1-2) , pp. 119-122. 10.1016/j.imlet.2012.10.002
file

Petrovas, C., Yamamoto, T., Price, David, Rao, S., Klatt, N., Brenchley, J., Douek, D., Gostick, Emma, Angermann, B., Grossman, Z., Macallan, D., Meier-Schellersheim, M. and Koup, R. 2013. High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance. Journal of Virology 87 (17) , pp. 9836-9844. 10.1128/JVI.01001-13
file

Beziat, V., Liu, L. L., Malmberg, J.-A., Ivarsson, M. A., Sohlberg, E., Bjorklund, A. T., Retiere, C., Sverremark-Ekstrom, E., Traherne, J., Ljungman, P., Schaffer, M., Price, David, Trowsdale, J., Michaelsson, J., Ljunggren, H.-G. and Malmberg, K.-J. 2013. NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRS. Blood 121 (14) , pp. 2678-2688. 10.1182/blood-2012-10-459545

Vavassori, Stefano, Kumar, Anil, Wan, Gan Siok, Ramanjaneyulu, Gundimeda S., Cavallari, Marco, El Daker, Sary, Beddoe, Travis, Theodossis, Alex, Williams, Neal K., Gostick, Emma, Price, David, Soudamini, Dinish U., Voon, Kong Kien, Olivo, Malini, Rossjohn, Jamie, Mori, Lucia and De Libero, Gennaro 2013. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nature Immunology 14 (9) , pp. 908-916. 10.1038/ni.2665

Budimir, Natalija, de Haan, Aalzen, Meijerhof, Tjarko, Gostick, Emma, Price, David, Huckriede, Anke and Wilschut, Jan 2013. Heterosubtypic cross-protection induced by whole inactivated influenza virus vaccine in mice: influence of the route of vaccine administration. Influenza and Other Respiratory Viruses 7 (6) , pp. 1202-1209. 10.1111/irv.12142
file

Price, David 2012. Horizons in Medicine 24: molecules, mechanisms and medicines [Editorial]. Clinical Medicine 12 (Supp 6) , s1. 10.7861/clinmedicine.12-6-s1
file

Humphreys, Ian R., Clement, Mathew, Marsden, Morgan, Ladell, Kristin Ingrid, McLaren, James Edward, Smart, Kathryn, Hindley, James Philip, Bridgeman, Hayley, van den Berg, Hugo A., Price, David, Ager, Ann, Wooldridge, Linda, Godkin, Andrew James and Gallimore, Awen Myfanwy 2012. Avidity of influenza-specific memory CD8+T-cell populations decays over time compromising antiviral immunity. European Journal of Immunology 42 (12) , pp. 3235-3242. 10.1002/eji.201242575

McCully, Michelle L., Ladell, Kristin Ingrid, Hakobyan, Svetlana, Mansel, Robert Edward, Price, David and Moser, Bernhard 2012. Epidermis instructs skin homing receptor expression in human T cells. Blood 120 (23) , pp. 4591-4598. 10.1182/blood-2012-05-433037

Baum, Paul D., Venturi, Vanessa and Price, David 2012. Wrestling with the repertoire: the promise and perils of next generation sequencing for antigen receptors. European Journal of Immunology 42 (11) , pp. 2834-2839. 10.1002/eji.201242999

Hindley, James Phillip, Jones, Emma, Smart, Kathryn, Bridgeman, Hayley, Lauder, Sarah Nicol, Ondondo, Beatrice Omusiro, Cutting, Scott, Ladell, Kristin Ingrid, Wynn, Katherine Kay, Withers, David, Price, David, Ager, Ann, Godkin, Andrew James and Gallimore, Awen Myfanwy 2012. T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T cell depletion. Cancer Research 72 (21) , pp. 5473-5482. 10.1158/0008-5472.CAN-12-1912

Ekeruche, Julia, Clement, Mathew, Cole, David, Edwards, Emily S. J., Ladell, Kristin Ingrid, Miles, John James, Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry Michael, Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre, Price, David, Wooldridge, Linda and Sewell, Andrew K. 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44) , pp. 37269-37281. 10.1074/jbc.M112.386409

Ekeruche-Makinde, Julia, Clement, Mathew, Cole, David K., Edwards, Emily S. J., Ladell, Kristin, Miles, John J., Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry M., Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre J., Price, David A., Wooldridge, Linda and Sewell, Andrew K. 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44) , pp. 37269-37281. 10.1074/jbc.M112.386409
file

Cole, David K., Laugel, Bruno, Clement, Mathew, Price, David A., Wooldridge, Linda and Sewell, Andrew K. 2012. The molecular determinants of CD8 co-receptor function. Immunology 137 (2) , pp. 139-148. 10.1111/j.1365-2567.2012.03625.x

Cole, David, Laugel, Bruno Frederic, Clement, Mathew, Price, David, Wooldridge, Linda and Sewell, Andrew K. 2012. The molecular determinants of CD8 co-receptor function. Immunology 137 (2) , pp. 139-148. 10.1111/j.1365-2567.2012.03625.x

Li, H., Ye, C., Ji, G., Wu, X., Xiang, Z., Li, Y., Cao, Y., Liu, X., Douek, D. C., Price, D. A. and Han, J. 2012. Recombinatorial biases and convergent recombination determine interindividual TCRβ sharing in murine thymocytes. Journal of Immunology 189 (5) , pp. 2404-2413. 10.4049/jimmunol.1102087

Li, Hanjie, Ye, Congting, Ji, Guoli, Wu, Xiaohui, Xiang, Zhe, Li, Yuanyue, Cao, Yonghao, Liu, Xiaolong, Douek, Daniel C., Price, David and Han, Jiahuai 2012. Recombinatorial biases and convergent recombination determine interindividual TCR  sharing in murine thymocytes. The Journal of Immunology 189 (5) , pp. 2404-2413. 10.4049/jimmunol.1102087

Budde, Melisa L., Greene, Justin M., Chin, Emily N., Ericsen, Adam J., Scarlotta, Matthew, Cain, Brian T., Pham, Ngoc H., Becker, Ericka A., Harris, Max, Weinfurter, Jason T., O'Connor, Shelby L., Piatak Jr., Michael, Lifson, Jeffrey D., Gostick, Emma, Price, David, Friedrich, Thomas C. and O'Connor, David H. 2012. Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques. Journal of Virology 86 (14) , pp. 7596-7604. 10.1128/JVI.00716-12
file

Johnson, M. J., Petrovas, C., Yamamoto, T., Lindsay, R. W. B., Lore, K., Gall, J. G. D., Gostick, E., Lefebvre, F., Cameron, M. J., Price, D. A., Haddad, E., Sekaly, R.-P., Seder, R. A. and Koup, R. A. 2012. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. Journal of Immunology 188 (12) , pp. 6109-6118. 10.4049/jimmunol.1103717

Johnson, Matthew J., Petrovas, Constantinos, Yamamoto, Takuya, Lindsay, Ross W. B., Lore, Karin, Gall, Jason G. D., Gostick, Emma, Lefebvre, François, Cameron, Mark J., Price, David, Haddad, Elias, Sekaly, Rafick-Pierre, Seder, Robert A. and Koup, Richard A. 2012. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. The Journal of Immunology 188 (12) , pp. 6109-6118. 10.4049/jimmunol.1103717

Liddy, Nathaniel, Bossi, Giovanna, Adams, Katherine J., Lissina, Anna, Mahon, Tara M., Hassan, Namir J., Gavarret, Jessie, Bianchi, Frayne C., Pumphrey, Nicholas J., Ladell, Kristin Ingrid, Gostick, Emma, Sewell, Andrew K., Lissin, Nikolai M., Harwood, Naomi E., Molloy, Peter E., Li, Yi, Cameron, Brian J., Sami, Malkit, Baston, Emma E., Todorov, Penio T., Paston, Samantha J., Dennis, Rebecca E., Harper, Jane V., Dunn, Steve M., Ashfield, Rebecca, Johnson, Andy, McGrath, Yvonne, Plesa, Gabriela, June, Carl H., Kalos, Michael, Price, David, Vuidepot, Annelise, Williams, Daniel D., Sutton, Deborah H. and Jakobsen, Bent K 2012. Monoclonal TCR-redirected tumor cell killing. Nature Medicine 18 (6) , pp. 980-987. 10.1038/nm.2764

Chattopadhyay, Pratip K., Gaylord, Brent, Palmer, Adrian, Jiang, Nan, Raven, Mary A., Lewis, Geoff, Reuter, Morgan A., Nur-ur Rahman, A. K. M., Price, David, Betts, Michael R. and Roederer, Mario 2012. Brilliant violet fluorophores: A new class of ultrabright fluorescent compounds for immunofluorescence experiments. Cytometry Part A 81A (6) , pp. 456-466. 10.1002/cyto.a.22043

Yamamoto, Takuya, Johnson, Matthew J., Price, David, Wolinsky, David I., Almeida, Jorge R., Petrovas, Constantinos, Nason, Martha, Yeh, Wendy W., Shen, Ling, Roederer, Mario, Rao, Srinivas S., McDermott, Adrian B., Lefebvre, Francois, Nabel, Gary J., Haddad, Elias K., Letvin, Norman L., Douek, Daniel C. and Koup, Richard A. 2012. Virus inhibition activity of effector memory CD8+ T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. Journal of Virology 86 (10) , pp. 5877-5884. 10.1128/JVI.00315-12
file

Mendoza, Daniel, Royce, Cassandra, Ruff, Laura E., Ambrozak, David R., Quigley, Maire F., Dang, Thurston, Venturi, Vanessa, Price, David, Douek, Daniel C., Migueles, Stephen A. and Connors, Mark 2012. HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells. Journal of Virology 86 (7) , pp. 4014-4018. 10.1128/JVI.06982-11
file

Bulek, Anna, Cole, David, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John, Gostick, Emma, Price, David, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre and Sewell, Andrew 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Bulek, Anna Marta, Cole, David, Skowera, Ania, Dolton, Garry Michael, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John James, Gostick, Emma, Price, David, Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre and Sewell, Andrew K. 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Cole, David, Gallagher, Kathleen, Lemercier, Brigitte, Holland, Christopher J., Junaid, Sayed, Hindley, James Phillip, Wynn, Katherine Kay, Gostick, Emma, Sewell, Andrew K., Gallimore, Awen Myfanwy, Ladell, Kristin Ingrid, Price, David, Gougeon, Marie-Lise and Godkin, Andrew James 2012. Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection. Nature Communications 3 , 665. 10.1038/ncomms1665

Janbazian, Loury, Price, David, Canderan, Glenda, Filali-Mouhim, Abdelali, Asher, Tedi E., Ambrozak, David R., Scheinberg, Phillip, Boulassel, Mohamad Rachid, Routy, Jean-Pierre, Koup, Richard A., Douek, Daniel C., Sekaly, Rafick-Pierre and Trautmann, Lydie 2012. Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation. The Journal of Immunology 188 (3) , pp. 1156-1167. 10.4049/jimmunol.1102610

Wooldridge, Linda, Ekeruche, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John James, Tan, Mai Ping, Dolton, Garry Michael, Clement, Mathew, Llewellyn-Lacey, Sian, Price, David, Peakman, Mark and Sewell, Andrew K. 2012. A single autoimmune T cell receptor recognizes more than a million different peptides. Journal of Biological Chemistry 287 (2) , pp. 1168-1177. 10.1074/jbc.M111.289488
file

Budimir, Natalija, Huckriede, Anke, Meijerhof, Tjarko, Boon, Louis, Gostick, Emma, Price, David, Wilschut, Jan and de Haan, Aalzen 2012. Induction of heterosubtypic cross-protection against influenza by a whole inactivated virus vaccine: the role of viral membrane fusion activity. PLoS ONE 7 (1) , e30898. 10.1371/journal.pone.0030898
file

Walker, Christopher M., Schmidt, Julia, Iversen, Astrid K. N., Tenzer, Stefan, Gostick, Emma, Price, David, Lohmann, Volker, Distler, Ute, Bowness, Paul, Schild, Hansjörg, Blum, Hubert E., Klenerman, Paul, Neumann-Haefelin, Christoph and Thimme, Robert 2012. Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted Hepatitis C virus-specific CD8+ T-cell epitope. PLoS Pathogens 8 (11) , e1003042. 10.1371/journal.ppat.1003042
file

Bridgeman, John S., Sewell, Andrew K., Miles, John James, Price, David A. and Cole, David K. 2012. Structural and biophysical determinants of ab T-cell antigen recognition. Immunology 135 (1) , pp. 9-18. 10.1111/j.1365-2567.2011.03515.x

Doherty, T. Mark, Antrobus, Richard D., Lillie, Patrick J., Berthoud, Tamara K., Spencer, Alexandra J., McLaren, James E., Ladell, Kristin Ingrid, Lambe, Teresa, Milicic, Anita, Price, David, Hill, Adrian V. S. and Gilbert, Sarah C. 2012. A T Cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years. PLoS ONE 7 (10) , e48322. 10.1371/journal.pone.0048322
file

Lugli, Enrico, Gattinoni, Luca, Roberto, Alessandra, Mavilio, Domenico, Price, David, Restifo, Nicholas P and Roederer, Mario 2012. Identification, isolation and in vitro expansion of human and nonhuman primate T stem cell memory cell. Nature Protocols 8 (1) , pp. 33-42. 10.1038/nprot.2012.143
file

Maloveste, Sebastien M., Chen, Dan, Gostick, Emma, Vivian, Julian P., Plishka, Ronald J., Iyengar, Ranjini, Kruthers, Robin L., Buckler-White, Alicia, Brooks, Andrew G., Rossjohn, Jamie, Price, David and Lafont, Bernard A. P. 2012. Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells. The Journal of Immunology 189 (9) , pp. 4338-4348. 10.4049/jimmunol.1201360

Wu, Y., Gao, F., Liu, J., Qi, J., Gostick, E., Price, David and Gao, G. F. 2011. Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus. The Journal of Immunology 187 (12) , pp. 6382-6392. 10.4049/jimmunol.1101726

Vivian, Julian P., Duncan, Renee C., Berry, Richard, O'Connor, Geraldine M., Reid, Hugh H., Beddoe, Travis, Gras, Stephanie, Saunders, Philippa M., Olshina, Maya A., Widjaja, Jacqueline M. L., Harpur, Christopher M., Lin, Jie, Maloveste, Sebastien M., Price, David, Lafont, Bernard A. P., McVicar, Daniel W., Clements, Craig S., Brooks, Andrew G. and Rossjohn, Jamie 2011. Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B [Letter]. Nature 479 (7373) , pp. 401-405. 10.1038/nature10517
file

Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M., Quigley, Maire F., Almeida, Jorge R., Gostick, Emma, Yu, Zhiya, Carpenito, Carmine, Wang, Ena, Douek, Daniel C., Price, David, June, Carl H., Marincola, Francesco M., Roederer, Mario and Restifo, Nicholas P. 2011. A human memory T cell subset with stem cell-like properties. Nature Medicine 17 (10) , pp. 1290-1297. 10.1038/nm.2446

Iglesias, M. C., Almeida, J. R., Fastenackels, S., van Bockel, D. J., Hashimoto, M., Venturi, V., Gostick, E., Urrutia, A., Wooldridge, L., Clement, Mathew, Gras, S., Wilmann, P. G., Autran, B., Moris, A., Rossjohn, Jamie, Davenport, M. P., Takiguchi, M., Brander, C., Douek, D. C., Kelleher, A. D., Price, David and Appay, V. 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8) , pp. 2138-2149. 10.1182/blood-2011-01-328781

Quigley, Máire F., Almeida, Jorge R., Price, David and Douek, Daniel C. 2011. Unbiased molecular analysis of T cell receptor expression using template-switch achored RT-PCR. Current Protocols in Immunology , 94:VII:10.33:10.33.1–10.33.16.. 10.1002/0471142735.im1033s94
file

Clement, Mathew, Ladell, Kristin Ingrid, Ekeruche, Julia, Miles, John James, Edwards, Emily, Dolton, Garry Michael, Williams, Tamsin, Schauenburg, Andrea J. A., Cole, David, Lauder, Sarah Nicol, Gallimore, Awen Myfanwy, Godkin, Andrew James, Burrows, Scott R., Price, David, Sewell, Andrew K. and Wooldridge, Linda 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187 (2) , pp. 654-663. 10.4049/jimmunol.1003941

Haney, Danielle, Quigley, Máire F., Asher, Tedi E., Ambrozak, David R., Gostick, Emma, Price, David, Douek, Daniel C. and Betts, Michael R. 2011. Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression. Journal of Immunological Methods 369 (1-2) , pp. 33-41. 10.1016/j.jim.2011.04.003
file

Kreutzman, A., Ladell, Kristin Ingrid, Koechel, C., Gostick, Emma, Ekblom, M., Stenke, L., Melo, T., Einsele, H., Porkka, K., Price, David, Mustjoki, S. and Seggewiss, R. 2011. Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation. Leukemia 25 (10) , pp. 1587-1597. 10.1038/leu.2011.135

Hindley, James Philip, Ferreira, Cristina, Jones, Emma, Lauder, Sarah Nicol, Ladell, Kristin, Wynn, Katherine, Betts, Gareth James, Singh, Yogesh, Price, David, Godkin, Andrew James, Dyson, Julian and Gallimore, Awen Myfanwy 2011. Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors. Cancer Research 71 (3) , pp. 736-746. 10.1158/0008-5472.CAN-10-1797

Burwitz, Benjamin J., Ende, Zachary, Sudolcan, Benjamin, Reynolds, Matthew, Greene, Justin M., Bimber, Benjamin N., Almeida, Jorge R., Kurniawan, Monica, Venturi, Vanessa, Gostick, Emma, Wiseman, Roger W., Douek, Daniel C., Price, David and O'Connor, David H. 2011. Simian immunodeficiency virus SIVmac239 nef vaccination elicits different tat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques. Journal of Virology 85 (7) , pp. 3683-3689. 10.1128/JVI.02112-10
file

Nagai, Kozo, Ochi, Toshiki, Fujiwara, Hiroshi, An, Jun, Shirakata, Toshiaki, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Melenhorst, J. Joseph, Gostick, Emma, Price, David, Ishii, Eiichi and Yasukawa, Masaki 2011. Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity. Blood 119 (2) , pp. 368-376. 10.1182/blood-2011-06-360354

Minassian, A. M., Rowland, R., Beveridge, N. E. R., Poulton, I. D., Satti, I., Harris, S., Poyntz, H., Hamill, M., Griffiths, K., Sander, C. R., Ambrozak, D. R., Price, David, Hill, B. J., Casazza, J. P., Douek, D. C., Koup, R. A., Roederer, M., Winston, A., Ross, J., Sherrard, J., Rooney, G., Williams, N., Lawrie, A. M., Fletcher, H. A., Pathan, A. A. and McShane, H. 2011. A phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults. BMJ Open 1 (2) , e000223. 10.1136/bmjopen-2011-000223
file

Schmidt, Julia, Neumann-Haefelin, Christoph, Altay, Tayibe, Gostick, Emma, Price, David, Lohmann, Volker, Blum, Hubert E. and Thimme, Robert 2011. Immunodominance of HLA-A2-restricted hepatitis C virus-specific CD8+ T cell responses is linked to naive-precursor frequency. Journal of Virology 85 (10) , pp. 5232-5236. 10.1128/JVI.00093-11
file

Berger, Christoph T., Frahm, Nicole, Price, David, Mothe, Beatriz, Ghebremichael, Musie, Hartman, Kari L., Henry, Leah M., Brenchley, Jason M., Ruff, Laura E., Venturi, Vanessa, Pereyra, Florencia, Sidney, John, Sette, Alessandro, Douek, Daniel C., Walker, Bruce D., Kaufmann, Daniel E. and Brander, Christian 2011. High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted gag-derived epitopes associated with relative HIV control. Journal of Virology 85 (18) , pp. 9334-9345. 10.1128/JVI.00460-11
file

O'Connor, Shelby L., Becker, Ericka A., Weinfurter, Jason T., Chin, Emily N., Budde, Melisa L., Gostick, Emma, Correll, Michael, Gleicher, Michael, Hughes, Austin L., Price, David, Friedrich, Thomas C. and O'Connor, David H. 2011. Conditional CD8+ T cell escape during acute simian immunodeficiency virus infection. Journal of Virology 86 (1) , pp. 605-609. 10.1128/JVI.05511-11
file

Sloand, Elaine M., Melenhorst, J. Joseph, Tucker, Zachary C. G., Pfannes, Loretta, Brenchley, Jason M., Yong, Agnes, Visconte, Valeria, Wu, Colin, Gostick, Emma, Scheinberg, Phillip, Olnes, Matthew J., Douek, Daniel C., Price, David, Barrett, A. John and Young, Neal S. 2011. T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy. Blood 117 (9) , pp. 2691-2699. 10.1182/blood-2010-04-277921

Yamamoto, Takuya, Price, David, Casazza, Joseph P., Ferrari, Guido, Nason, Martha, Chattopadhyay, Pratip K., Roederer, Mario, Gostick, Emma, Katsikis, Peter D., Douek, Daniel C., Haubrich, Richard, Petrovas, Constantinos and Koup, Richard A. 2011. Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood 117 (18) , pp. 4805-4815. 10.1182/blood-2010-11-317297

Laugel, Bruno Frederic, Cole, David, Clement, Mathew, Wooldridge, Linda, Price, David and Sewell, Andrew K. 2011. The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells. Journal of Leukocyte Biology 90 (6) , pp. 1089-1099. 10.1189/jlb.0611316

Iglesias, Maria Candela, Almeida, Jorge R., Fastenackels, Solene, van Bockel, David J., Hashimoto, Masao, Venturi, Vanessa, Gostick, Emma, Urrutia, Alejandra, Wooldridge, Linda, Clement, Mathew, Gras, Stephanie, Wilmann, Pascal G., Autran, Brigitte, Moris, Arnaud, Rossjohn, Jamie, Davenport, Miles P., Takiguchi, Masafumi, Brander, Christian, Douek, Daniel C., Kelleher, Anthony D., Price, David and Appay, Victor 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8) , pp. 2138-2149. 10.1182/blood-2011-01-328781

Vojnov, Lara, Martins, Mauricio A., Almeida, Jorge R., Ende, Zachary, Rakasz, Eva G., Reynolds, Matthew R., Leon, Enrique J., Weisgrau, Kim L., Burwitz, Benjamin J., Folkvord, Joy M., Veloso de Santana, Marlon G., Costa Neves, Patrícia C., Connick, Elizabeth, Skinner, Pamela J., Gostick, Emma, O'Connor, David H., Wilson, Nancy A., Bonaldo, Myrna C., Galler, Ricardo, Price, David, Douek, Danny C. and Watkins, David I. 2011. GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo. PLoS ONE 6 (8) , e23515. 10.1371/journal.pone.0023515
file

Ruckwardt, Tracy J., Malloy, Allison M. W., Gostick, Emma, Price, David, Dash, Pradyot, McClaen, Jennifer L., Thonas, Paul G. and Graham, Barney S. 2011. Neonatal cd8 t-cell hierarchy is distinct from adults and is influenced by intrinsic t cell properties in respiratory syncytial virus infected mice. PLoS Pathogens 7 (12) , e1002377. 10.1371/journal.ppat.1002377
file

Venturi, Vanessa, Quigley, Maire F., Greenaway, Hui Yee, Ng, Pauline C., Ende, Zachary S., McIntosh, Tina, Asher, Tedi E., Almeida, Jorge R., Levy, Samuel, Price, David, Davenport, Miles P. and Douek, Daniel C. 2011. A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing. The Journal of Immunology 186 (7) , pp. 4285-4294. 10.4049/jimmunol.1003898

Falkenburg, Willem J. J., Melenhorst, J. Joseph, van de Meent, Marian, Kester, Michel, Hombrink, Pleun, Heemskerk, Mirjam H. M., Hagedoorn, Renate S., Gostick, Emma, Price, David, Falkenburg, J. H. Frederik, Barrett, A. John and Jedema, Inge 2011. Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity. The Journal of Immunology 187 (5) , pp. 2824-2833. 10.4049/jimmunol.1100852

Miles, John James, Douek, Daniel C. and Price, David 2011. Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination. Immunology and Cell Biology 89 (3) , pp. 375-387. 10.1038/icb.2010.139

van Bockel, David J., Price, David, Munier, Mee Ling, Venturi, Vanessa, Asher, Tedi E., Ladell, Kristin Ingrid, Greenaway, Hui Yee, Zaunders, John, Douek, Daniel C., Cooper, David A., Davenport, Miles P. and Kelleher, Anthony D. 2010. Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response. The Journal of Immunology 186 (1) , pp. 359-371. 10.4049/jimmunol.1001807

Quigley, Maire F., Greenaway, Hui Yee, Venturi, Vanessa, Lindsay, Ross, Quinn, Kylie M., Seder, Robert A., Douek, Daniel C., Davenport, Miles P. and Price, David 2010. Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire. Proceedings of the National Academy of Sciences of the United States of America 107 (45) , pp. 19414-19419. 10.1073/pnas.1010586107

Humphreys, Ian R., Lee, Seung-Woo, Jones, Morgan, Loewendorf, Andrea, Gostick, Emma, Price, David A., Benedict, Chris A., Ware, Carl F. and Croft, Michael 2010. Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells. European Journal of Immunology 40 (10) , pp. 2762-2768. 10.1002/eji.200940256

Jones, Morgan, Ladell, Kristin Ingrid, Wynn, Katherine, Stacey, Maria A., Quigley, Maire F., Gostick, Emma, Price, David and Humphreys, Ian R. 2010. IL-10 restricts memory T cell inflation during cytomegalovirus infection. The Journal of Immunology 185 (6) , pp. 3583-3592. 10.4049/jimmunol.1001535

Cole, David, Edwards, Emily, Wynn, Katherine, Clement, Mathew, Miles, John James, Ladell, Kristin Ingrid, Ekeruche, Julia, Gostick, Emma, Adams, Katherine J., Skowera, Ania, Peakman, Mark, Wooldridge, Linda, Price, David A. and Sewell, Andrew K. 2010. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. The Journal of Immunology 185 (4) , pp. 2600-2610. 10.4049/jimmunol.1000629

Rosario, Maximillian, Bridgeman, Anne, Quakkelaar, Esther D., Quigley, Maire F., Hill, Brenna J., Knudsen, Maria L., Ammendola, Virginia, Ljungberg, Karl, Borthwick, Nicola, Im, Eung-Jun, McMichael, Andrew J., Drijfhout, Jan W., Greenaway, Hui Yee, Venturi, Vanessa, Douek, Daniel C., Colloca, Stefano, Liljeström, Peter, Nicosia, Alfredo, Price, David A., Melief, Cornelis J. M. and Hanke, Tomás 2010. Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques. European Journal of Immunology 40 (7) , pp. 1973-1984. /10.1002/eji.201040344

Wooldridge, Linda, Laugel, Bruno Frederic, Ekeruche, Julia, Clement, Mathew, van den Berg, Hugo A., Price, David and Sewell, Andrew K. 2010. CD8 controls T cell cross-reactivity. The Journal of Immunology 185 (8) , pp. 4625-4632. 10.4049/jimmunol.1001480

Greene, Justin M., Lhost, Jennifer J., Burwitz, Benjamin J., Budde, Melisa L., Macnair, Caitlin E., Weiker, Madelyn K., Gostick, Emma, Friedrich, Thomas C., Broman, Karl W., Price, David, O'Connor, Shelby L. and O'Connor, David H. 2010. Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239 nef-vaccinated macaques suppress SIVmac239 replication ex vivo. Journal of Virology 84 (7) , pp. 3362-3372. 10.1128/JVI.02028-09
file

Chattopadhyay, Pratip K., Roederer, Mario and Price, David A. 2010. OMIP-002: Phenotypic analysis of specific human CD8+ T-cells using peptide-MHC class I multimers for any of four epitopes. Cytometry Part A 77A (9) , pp. 821-822. 10.1002/cyto.a.20945

Schaubert, Keri L., Price, David A., Salkowitz, Janelle R., Sewell, Andrew K., Sidney, John, Asher, Tedi, Blondelle, Sylvie E., Adams, Sharon, Marincola, Francesco M., Joseph, Aviva, Sette, Alessandro, Douek, Daniel C., Ayyavoo, Velpandi, Storkus, Walter, Leung, Ming-Ying, Ng, Hwee, Yang, Otto O., Goldstein, Harris, Wilson, Darcy B. and Kan-Mitchell, June 2010. Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes. European Journal of Immunology 40 (7) , pp. 1950-1962. 10.1002/eji.200940079

Wooldridge, Linda, Clement, Mathew, Lissina, Anna, Edwards, Emily, Ladell, Kristin Ingrid, Ekeruche, Julia, Hewitt, R. E., Laugel, Bruno Frederic, Gostick, Emma, Cole, David, Debets, R., Berrevoets, C., Miles, John James, Burrows, S. R., Price, David A. and Sewell, Andrew K. 2010. MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. Journal of Immunology 184 (7) , pp. 3357-3366. 10.4049/jimmunol.0902398

Van Tendeloo, V. F., Van de Velde, A., Van Driessche, A., Cools, N., Anguille, S., Ladell, Kristin Ingrid, Gostick, Emma, Vermeulen, K., Pieters, K., Nijs, G., Stein, B., Smits, E. L., Schroyens, W. A., Gadisseur, A. P., Vrelust, I., Jorens, P. G., Goossens, H., de Vries, I. J., Price, David A., Oji, Y., Oka, Y., Sugiyama, H. and Berneman, Z. N. 2010. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proceedings of the National Academy of Sciences of the United States of America 107 (31) , pp. 13824-13829. 10.1073/pnas.1008051107

Giannopoulos, K., Dmoszynska, A., Kowal, M., Rolinski, J., Gostick, Emma, Price, David, Greiner, J., Rojewski, M., Stilgenbauer, S., Döhner, H. and Schmitt, M. 2010. Peptide vaccination elicits leukemia-associated antigen-specific cytotoxic CD8+ T-cell responses in patients with chronic lymphocytic leukemia. Leukemia 24 (4) , pp. 798-805. 10.1038/leu.2010.29

Rosario, Maximillian, Hopkins, Richard, Fulkerson, John, Borthwick, Nicola, Quigley, Maire F., Joseph, Joan, Douek, Daniel C., Greenaway, Hui Yee, Venturi, Vanessa, Gostick, Emma, Price, David, Both, Gerald W., Sadoff, Jerald C. and Hanke, Tomas 2010. Novel recombinant mycobacterium bovis BCG, ovine atadenovirus, and modified vaccinia virus ankara vaccines combine to induce robust human immunodeficiency virus-specific CD4 and CD8 T-cell responses in rhesus macaques. Journal of Virology 84 (12) , pp. 5898-5908. 10.1128/JVI.02607-09
file

Harris, L. D., Klatt, N. R., Vinton, C., Briant, J. A., Tabb, B., Ladell, Kristin Ingrid, Lifson, Jeffrey, Estes, J. D., Price, David, Hirsch, V. M. and Brenchley, J. M. 2010. Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques. Blood 116 (20) , pp. 4148-4157. 10.1182/blood-2010-05-283549

Melenhorst, J. Joseph, Leen, Ann M., Bollard, Catherine M., Quigley, Maire F., Price, David, Rooney, Cliona M., Brenner, Malcolm K., Barrett, A. John and Heslop, Helen E. 2010. Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects. Blood 116 (22) , pp. 4700-4702. 10.1182/blood-2010-06-289991

Miles, John James, Bulek, Anna Marta, Cole, David, Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry Michael, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David, Rizkallah, Pierre and Sewell, Andrew K. 2010. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathogens 6 (11) , e1001198. 10.1371/journal.ppat.1001198
file

Subramanya, Sandesh, Armant, Myriam, Salkowitz, Janelle R., Nyakeriga, Alice M., Haridas, Viraga, Hasan, Maroof, Bansal, Anju, Goepfert, Paul A., Wynn, Katherine, Ladell, Kristin Ingrid, Price, David, N, Manjunath, Kan-Mitchell, June and Shankar, Premlata 2010. Enhanced induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic cell-targeted delivery of SOCS-1 siRNA. Molecular Therapy 18 (11) , pp. 2028-2037. 10.1038/mt.2010.148

Burwitz, B. J., Bimber, B. N., O'Connor, S., Detmer, A., Gostick, Emma, Lank, S. M., Price, David A., Hughes, A. and O'Connor, D. 2009. P20-16. Ultra-deep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in SIV-infected macaques. Retrovirology 6 (S3) , P386. 10.1186/1742-4690-6-S3-P386
file

Price, David A., Asher, Tedi E., Wilson, Nancy A., Nason, Martha C., Brenchley, Jason M., Metzler, Ian S., Venturi, Vanessa, Gostick, Emma, Chattopadhyay, Pratip K., Roederer, Mario, Davenport, Miles P., Watkins, David I. and Douek, Daniel C. 2009. Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection. Journal of Experimental Medicine 206 (4) , pp. 923-936. 10.1084/jem.20081127
file

Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Gostick, Emma, Ladell, Kristin Ingrid, Roederer, Mario, Hensel, Nancy F., Douek, Daniel C., Barrett, A. John and Price, David 2009. High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow. Blood 113 (10) , pp. 2238-2244. 10.1182/blood-2008-04-151969

Bimber, Benjamin N., Burwitz, Benjamin J., O'Connor, Shelby, Detmer, Ann, Gostick, Emma, Lank, Simon M., Price, David, Hughes, Austin and O'Connor, David 2009. Ultradeep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in simian immunodeficiency virus-infected macaques. Journal of Virology 83 (16) , pp. 8247-8253. 10.1128/JVI.00897-09
file

Lissina, Anna, Ladell, Kristin Ingrid, Skowera, Ania, Clement, Mathew, Edwards, Emily, Seggewiss, Ruth, van den Berg, Hugo A., Gostick, Emma, Gallagher, Kathleen, Jones, Emma, Melenhorst, J. Joseph, Godkin, Andrew James, Peakman, Mark, Price, David, Sewell, Andrew K. and Wooldridge, Linda 2009. Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. Journal of Immunological Methods 340 (1) , pp. 11-24. 10.1016/j.jim.2008.09.014
file

Almeida, J., Sauce, D., Price, David A., Papagno, L., Shin, S., Moris, A., Larsen, M., Pancino, G., Douek, D., Autran, B., Saez-Cirion, A. and Appay, V. 2009. P16-17. Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV suppressive activity. Retrovirology 6 (3) , P246. 10.1186/1742-4690-6-S3-P246
file

Cole, David, Yuan, Fang, Rizkallah, Pierre, Miles, John James, Gostick, Emma, Price, David, Gao, George F., Jakobsen, Bent K. and Sewell, Andrew K. 2009. Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. Journal of Biological Chemistry 284 (40) , 27281-27289. 10.1074/jbc.M109.022509

Wooldridge, Linda, Lissina, Anna, Cole, David, van den Berg, Hugo A., Price, David and Sewell, Andrew K. 2009. Tricks with tetramers: how to get the most from multimeric peptide-MHC. Immunology 126 (2) , pp. 147-164. 10.1111/j.1365-2567.2008.02848.x

Geldmacher, Christof, Metzler, Ian S., Tovanabutra, Sodsai, Asher, Tedi E., Gostick, Emma, Ambrozak, David R., Petrovas, Constantinos, Schuetz, Alexandra, Ngwenyama, Njabulo, Kijak, Gustavo, Maboko, Leonard, Hoelscher, Michael, McCutchan, Francine, Price, David, Douek, Daniel C. and Koup, Richard A. 2009. Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response. Blood 114 (8) , pp. 1553-1562. 10.1182/blood-2009-02-206193

Almeida, Jorge R., Sauce, Delphine, Price, David, Papagno, Laura, Shin, So Youn, Moris, Arnaud, Larsen, Martin, Pancino, Gianfranco, Douek, Daniel C., Autran, Brigitte, Saez-Cirion, Asier and Appay, Victor 2009. Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 113 (25) , pp. 6351-6360. 10.1182/blood-2009-02-206557

Scheinberg, Phillip, Melenhorst, Jan J., Brenchley, Jason M., Hill, Brenna J., Hensel, Nancy F., Chattopadhyay, Pratip K., Roederer, Mario, Picker, Louis J., Price, David, Barrett, A. John and Douek, Daniel C. 2009. The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor. Blood 114 (24) , pp. 5071-5080. 10.1182/blood-2009-04-214684

Chattopadhyay, Pratip K., Betts, Michael R., Price, David, Gostick, Emma, Horton, Helen, Roederer, Mario and De Rosa, Stephen C. 2009. The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression. Journal of Leukocyte Biology 85 (1) , pp. 88-97. 10.1189/jlb.0208107

Nakamoto, Nobuhiro, Cho, Hyosun, Shaked, Abraham, Olthoff, Kim, Valiga, Mary E., Kaminski, Mary, Gostick, Emma, Price, David, Freeman, Gordon J., Wherry, E. John and Chang, Kyong-Mi 2009. Synergistic reversal of intrahepatic hcv-specific cd8 t cell exhaustion by combined pd-1/ctla-4 blockade. PLoS Pathogens 5 (2) , e1000313. 10.1371/journal.ppat.1000313
file

Petrovas, Constantinos, Chaon, Benjamin, Ambrozak, David R., Price, David, Melenhorst, J. Joseph, Hill, Brenna J., Geldmacher, Christof, Casazza, Joseph P., Chattopadhyay, Pratip K., Roederer, Mario, Douek, Daniel C., Mueller, Yvonne M., Jacobson, Jeffrey M., Kulkarni, Viraj, Felber, Barbara K., Pavlakis, George N., Katsikis, Peter D. and Koup, Richard A. 2009. Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection. The Journal of Immunology 183 (2) , pp. 1120-1132. 10.4049/jimmunol.0900182

Honda, Mitsuo, Wang, Rui, Kong, Wing-Pui, Kanekiyo, Masaru, Akahata, Wataru, Xu, Ling, Matsuo, Kazuhiro, Natarajan, Kannan, Robinson, Howard, Asher, Tedi E., Price, David, Douek, Daniel C., Margulies, David H. and Nabel, Gary J. 2009. Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity. The Journal of Immunology 183 (4) , pp. 2425-2434. 10.4049/jimmunol.0900581

Greenaway, Hui Yee, Kurniawan, Monica, Price, David, Douek, Daniel C., Davenport, Miles P. and Venturi, Vanessa 2009. Extraction and characterization of the rhesus macaque T-cell receptor β-chain genes. Immunology and Cell Biology 87 (7) , pp. 546-553. 10.1038/icb.2009.38

Venturi, Vanessa, Chin, Hui Yee, Tedi, E. Asher, Ladell, Kristin Ingrid, Scheinberg, Phillip, Bornstein, Ethan, van Bockel, David, Kelleher, Anthony D., Douek, Daniel C., Price, David A. and Davenport, Miles P. 2008. TCR β-Chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV. Journal of Immunology 181 (11) , pp. 7853-7862. 10.4049/​jimmunol.181.11.7853

Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Lissina, Anna, Gostick, Emma, Cole, David, Wooldridge, Linda, van den Berg, Hugo A., Bornstein, Ethan, Hensel, Nancy F., Douek, Daniel C., Roederer, Mario, Sewell, Andrew K., Barrett, A. John and Price, David 2008. Detection of low avidity CD8+ T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers. Journal of Immunological Methods 338 (1-2) , pp. 31-39. 10.1016/j.jim.2008.07.008

Ebinuma, Hirotoshi, Nakamoto, Nobuhiro, Li, Yun, Price, David, Gostick, Emma, Levine, Bruce L., Tobias, J., Kwok, William W. and Chang, Kyong-Mi 2008. Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection. Journal of Virology 82 (10) , pp. 5043-5053. 10.1128/JVI.01548-07
file

Rehr, Manuela, Cahenzli, Julia, Haas, Anna, Price, David, Gostick, Emma, Huber, Milo, Karrer, Urs and Oxenius, Annette 2008. Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. Journal of Virology 82 (7) , pp. 3391-3404. 10.1128/JVI.02383-07
file

Seggewiss, R., Price, David and Purbhoo, Ma 2008. Immunomodulatory effects of imatinib and second-generation tyrosine kinase inhibitors on T cells and dendritic cells: an update. Cytotherapy 10 (6) , pp. 633-641. 10.1080/14653240802317639

Melenhorst, J.J, Scheinberg, P., Lu, J., Ambrozak, D.R, Sosa, E., Zhao, L., Hensel, N.F., Savani, B.N., Douek, D.C., Price, David and Barrett, A.J. 2008. Regulatory T-cell depletion does not prevent emergence of new CD25+ FOXP3+ lymphocytes after antigen stimulation in culture. Cytotherapy 10 (2) , pp. 152-164. 10.1080/14653240701853536

Weichsel, Ralf, Dix, Carolin, Wooldridge, Linda, Clement, Mathew, Fenton-May, Angharad, Sewell, Andrew K., Zezula, Josef, Greiner, Elizabeth, Gostick, Emma, Price, David, Einsele, Hermann and Seggewiss, Ruth 2008. Profound inhibition of antigen-specific T-cell effector functions by dasatinib. Clinical Cancer Research 14 (8) , pp. 2484-2491. 10.1158/1078-0432.CCR-07-4393

Price, David, Bitmansour, Arlene D., Edgar, John B., Walker, Joshua M., Axthelm, Michael K., Douek, Daniel C. and Picker, Louis J. 2008. Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques. Journal of Immunology 180 (1) , pp. 269-280. 10.4049/jimmunol.180.1.269

Melenhorst, J. Joseph, Lay, Matthew D. H., Price, David A., Adams, Sharon D., Zeilah, Joseph, Sosa, Edgardo, Hensel, Nancy F., Follmann, Dean, Douek, Daniel C., Davenport, Miles P. and Barrett, A. John 2008. Contribution of TCR-beta locus and HLA to the shape of the mature human Vbeta repertoire. Journal of Immunology 180 (10) , pp. 6484-6489.

Venturi, Vanessa, Chin, Hui Yee, Price, David A., Douek, Daniel C. and Davenport, Miles P. 2008. The role of production frequency in the sharing of simian immunodeficiency virus-specific CD8+ TCRs between macaques. Journal of Immunology 181 (4) , pp. 2597-2609. 10.4049/jimmunol.181.4.2597

Chattopadhyay, Pratip K., Melenhorst, J. Joseph, Ladell, Kristin Ingrid, Gostick, Emma, Scheinberg, Phillip, Barrett, A. John, Wooldridge, Linda, Roederer, Mario, Sewell, Andrew K. and Price, David A. 2008. Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+T cells with peptide-major histocompatibility complex class I tetramers. Cytometry Part A 73A (11) , pp. 1001-1009. 10.1002/cyto.a.20642

Reynolds, M. R., Weiler, A. M., Weisgrau, K. L., Piaskowski, S. M., Furlott, J. R., Weinfurter, J. T., Kaizu, M., Soma, T., Leon, E. J., MacNair, C., Leaman, D. P., Zwick, M. B., Gostick, Emma, Musani, S. K., Price, David, Friedrich, T. C., Rakasz, E. G., Wilson, N. A., McDermott, A. B., Boyle, R., Allison, D. B., Burton, D. R., Koff, W. C. and Watkins, D. I. 2008. Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. Journal of Experimental Medicine 205 (11) , pp. 2537-2550. 10.1084/jem.20081524
file

Nakamoto, Nobuhiro, Kaplan, David E., Coleclough, Jennifer, Li, Yun, Valiga, Mary E., Kaminski, Mary, Shaked, Abraham, Olthoff, Kim, Gostick, Emma, Price, David, Freeman, Gordon J., Wherry, E. John and Chang, Kyong-Mi 2008. Functional restoration of HCV-specific CD8 T Cells by PD-1 blockade is defined by PD-1 expression and compartmentalization. Gastroenterology 134 (7) , pp. 1927-1937. 10.1053/j.gastro.2008.02.033

Smith, Miranda Z., Asher, Tedi E., Venturi, Vanessa, Davenport, Miles P., Douek, Daniel C., Price, David and Kent, Stephen J. 2008. Limited maintenance of vaccine-induced simian immunodeficiency virus-specific CD8 T-cell receptor clonotypes after virus challenge. Journal of Virology 82 (15) , pp. 7357-7368. 10.1128/JVI.00607-08
file

Daucher, Marybeth, Price, David, Brenchley, Jason M., Lamoreaux, Laurie, Metcalf, Julia A., Rehm, Catherine, Nies-Kraske, Elizabeth, Urban, Elizabeth, Yoder, Christian, Rock, Diane, Gumkowski, Julie, Betts, Michael R., Dybul, Mark R. and Douek, Daniel C. 2008. Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. Journal of Virology 82 (8) , pp. 4102-4114. 10.1128/JVI.02212-07
file

Mielke, Stephan, Nunes, Raquel, Rezvani, Katayoun, Fellowes, Vicki S., Venne, Annie, Solomon, Scott R., Fan, Yong, Gostick, Emma, Price, David, Scotto, Christian, Read, Elizabeth J. and Barrett, A. John 2008. A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique. Blood 111 (8) , pp. 4392-4402. 10.1182/blood-2007-08-104471

Brenchley, Jason M., Paiardini, Mirko, Knox, Kenneth S., Asher, Ava I., Cervasi, Barbara, Asher, Tedi E., Scheinberg, Phillip, Price, David, Hage, Chadi A., Kholi, Lisa M., Khoruts, Alexander, Frank, Ian, Else, James, Schacker, Timothy, Silvestri, Guido and Douek, Daniel C. 2008. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112 (7) , pp. 2826-2835. 10.1182/blood-2008-05-159301

Hestvik, A. L. K., Skorstad, G., Price, David, Vartdal, F. and Holmoy, T. 2008. Multiple sclerosis: glatiramer acetate induces anti-inflammatory T cells in the cerebrospinal fluid. Multiple Sclerosis Journal 14 (6) , pp. 749-758. 10.1177/1352458508089411

Appay, Victor, Douek, Daniel C. and Price, David 2008. CD8+ T cell efficacy in vaccination and disease. Nature Medicine 14 (6) , pp. 623-628. 10.1038/nm.f.1774

Venturi, Vanessa, Price, David, Douek, Daniel C. and Davenport, Miles P. 2008. The molecular basis for public T-cell responses? Nature Reviews Immunology 8 (3) , pp. 231-238. 10.1038/nri2260

Brenchley, J. M., Knox, K. S., Asher, A. I., Price, David, Kohli, L. M., Gostick, Emma, Hill, B. J., Hage, C. A., Brahmi, Z., Khoruts, A., Twigg, H. L., Schacker, T. W. and Douek, D. C. 2008. High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage. Mucosal Immunology 1 (1) , pp. 49-58. 10.1038/mi.2007.5

Melenhorst, J. J., Lay, M. D. H., Price, David, Adams, S. D., Zeilah, J., Sosa, E., Hensel, N. F., Follmann, D., Douek, D. C., Davenport, M. P. and Barrett, A. J. 2008. Contribution of TCR- locus and HLA to the shape of the mature human V repertoire. The Journal of Immunology 180 (10) , pp. 6484-6489. 10.4049/jimmunol.180.10.6484

Loffredo, John T., Friedrich, Thomas C., León, Enrique J., Stephany, Jason J., Rodrigues, Denise S., Spencer, Sean P., Bean, Alex T., Beal, Dominic R., Burwitz, Benjamin J., Rudersdorf, Richard A., Wallace, Lyle T., Piaskowski, Shari M., May, Gemma E., Sidney, John, Gostick, Emma, Wilson, Nancy A., Price, David, Kallas, Esper G., Piontkivska, Helen, Hughes, Austin L., Sette, Alessandro and Watkins, David I. 2007. Cd8+ T cells from siv elite controller macaques recognize mamu-b*08-bound epitopes and select for widespread viral variation. PLoS ONE 2 (11) , e1152. 10.1371/journal.pone.0001152
file

Laugel, Bruno Frederic, Berg, Hugo A. van den, Gostick, Emma, Cole, David, Wooldridge, Linda, Boulter, Jonathan M, Milicic, Anita, Price, David and Sewell, Andrew 2007. Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotxic T lymphocyte activation and tetramer properties. The Journal of Biological Chemistry 282 (33) , pp. 23799-22810. 10.1074/jbc.M700976200
file

Cole, David, Pumphrey, Nicholas J., Boulter, Jonathan M., Sami, Malkit, Bell, John I., Gostick, Emma, Price, David, Gao, George F., Sewell, Andrew K. and Jakobsen, Bent K. 2007. Human TCR-binding affinity is governed by MHC class restriction. The Journal of Immunology 178 (9) , pp. 5727-5734. 10.4049/​jimmunol.178.9.5727

Wooldridge, Linda, Lissina, Anna, Vernazza, Jonathan, Gostick, Emma, Laugel, Bruno Frederic, Hutchinson, Sarah L., Mirza, Fareed, Dunbar, P. Rod, Boulter, Jonathan M., Glick, Meir, Cerundolo, Vincenzo, Berg, Hugo A. van den, Price, David and Sewell, Andrew 2007. Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region. European Journal of Immunology 37 (5) , pp. 1323-1333. 10.1002/eji.200636765

Scheinberg, Phillip, Melenhorst, Jan J., Hill, Brenna J., Keyvanfar, Keyvan, Barrett, A. John, Price, David and Douek, Daniel C. 2007. The clonal composition of human CD4+CD25+Foxp3+ cells determined by a comprehensive DNA-based multiplex PCR for TCRB gene rearrangements. Journal of Immunological Methods 321 (1-2) , pp. 107-120. 10.1016/j.jim.2007.01.005
file

Gostick, Emma, Cole, David, Hutchinson, Sarah L., Wooldridge, Linda, Tafuro, Sabrina, Laugel, Bruno Frederic, Lissina, A., Oxenius, Annette, Boulter, Jonathan M., Price, David and Sewell, Andrew K. 2007. Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor. European Journal of Immunology 37 (2) , pp. 479-486. 10.1002/eji.200636243

Maness, Nicholas J., Valentine, Laura E., May, Gemma E., Reed, Jason, Piaskowski, Shari M., Soma, Taeko, Furlott, Jessica, Rakasz, Eva G., Friedrich, Thomas C., Price, David, Gostick, Emma, Hughes, Austin L., Sidney, John, Sette, Alessandro, Wilson, Nancy A. and Watkins, David I. 2007. AIDS virus-specific CD8+T lymphocytes against an immunodominant cryptic epitope select for viral escape. Journal of Experimental Medicine 204 (11) , pp. 2505-2512. 10.1084/jem.20071261
file

Beveridge, Natalie, Price, David, Casazza, Joseph, Pathan, Ansar, Sander, Clare, Asher, Tedi, Ambrozak, David, Precopio, MelissaL., Scheinberg, Phillip, Alder, Nicola C., Roederer, Mario, Koup, Richard A., Douek, Daniel C., Hill, Adrian V. S. and McShane, Helen 2007. Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctionalMycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations. European Journal of Immunology 37 (11) , pp. 3089-3100. 10.1002/eji.200737504

Almeida, Jorge R., Price, David, Papagno, Laura, Arkoub, Zaïna Aït, Sauce, Delphine, Bornstein, Ethan, Asher, Tedi E., Samri, Assia, Schnuriger, Aurélie, Theodorou, Ioannis, Costagliola, Dominique, Rouzioux, Christine, Agut, Henri, Marcelin, Anne-Geneviève, Douek, Daniel, Autran, Brigitte and Appay, Victor 2007. Superior control of HIV-1 replication by CD8+T cells is reflected by their avidity, polyfunctionality, and clonal turnover. Journal of Experimental Medicine 204 (10) , pp. 2473-2485. 10.1084/jem.20070784
file

Yuan, Fang, Georgiou, Theonie, Hillon, Theresa, Gostick, Emma, Price, David, Sewell, Andrew K., Moysey, Ruth, Gavarret, Jessie, Vuidepot, Annelise, Sami, Malkit, Bell, John I., Gao, George F., Rizkallah, Pierre J. and Jakobsen, Bent K. 2007. Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 63 (9) , pp. 758-760. 10.1107/S1744309107037244
file

van Bockel, David, Price, David, Asher, Tedi E., Venturi, Vanessa, Suzuki, Kazuo, Warton, Kristina, Davenport, Miles P., Cooper, David A., Douek, Daniel C. and Kelleher, Anthony D. 2007. Validation of RNA-based molecular clonotype analysis for virus-specific CD8+ T-cells in formaldehyde-fixed specimens isolated from peripheral blood. Journal of Immunological Methods 326 (1-2) , pp. 127-138. 10.1016/j.jim.2007.07.016

Rezvani, K., Yong, A. S. M., Savani, B. N., Mielke, S., Keyvanfar, K., Gostick, E., Price, David, Douek, D. C. and Barrett, A. J. 2007. Graft-versus-leukemia effects associated with detectable Wilms tumor-1-specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia. Blood 110 (6) , pp. 1924-1932. 10.1182/blood-2007-03-076844

Purbhoo, M. A., Li, Y., Sutton, D. H., Brewer, J. E., Gostick, E., Bossi, G., Laugel, B., Moysey, R., Baston, E., Liddy, N., Cameron, B., Bennett, A. D., Ashfield, R., Milicic, A., Price, David, Classon, B. J., Sewell, A. K. and Jakobsen, B. K. 2007. The HLA A*0201-restricted hTERT540-548 peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor. Molecular Cancer Therapeutics 6 (7) , pp. 2081-2091. 10.1158/1535-7163.MCT-07-0092

Petrovas, C., Price, David, Mattapallil, J., Ambrozak, D. R., Geldmacher, C., Cecchinato, V., Vaccari, M., Tryniszewska, E., Gostick, E., Roederer, M., Douek, D. C., Morgan, S. H., Davis, S. J., Franchini, G. and Koup, R. A. 2007. SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection. Blood 110 (3) , pp. 928-936. 10.1182/blood-2007-01-069112

Schaubert, K. L., Price, David, Frahm, N., Li, J., Ng, H. L., Joseph, A., Paul, E., Majumder, B., Ayyavoo, V., Gostick, E., Adams, S., Marincola, F. M., Sewell, Andrew K., Altfeld, M., Brenchley, J. M., Douek, D. C., Yang, O. O., Brander, C., Goldstein, H. and Kan-Mitchell, J. 2007. Availability of a diversely Avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 gag p2419-27 epitope. The Journal of Immunology 178 (12) , pp. 7756-7766. 10.4049/jimmunol.178.12.7756

Precopio, Melissa L., Betts, Michael R., Parrino, Janie, Price, David, Gostick, Emma, Ambrozak, David R., Asher, Tedi E., Douek, Daniel C., Harari, Alexandre, Pantaleo, Giuseppe, Bailer, Robert, Graham, Barney S., Roederer, Mario and Koup, Richard A. 2007. Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+T cell responses. Journal of Experimental Medicine 204 (6) , p. 1405. 10.1084/jem.20062363
file

Davenport, M., Price, David and McMichael, A. 2007. The T cell repertoire in infection and vaccination: implications for control of persistent viruses. Current Opinion in Immunology 19 (3) , pp. 294-300. 10.1016/j.coi.2007.04.001

Laugel, Bruno, Price, David, Milicic, Anita and Sewell, Andrew K. 2007. CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions. European Journal of Immunology 37 (4) , pp. 905-913. 10.1002/eji.200636718

Hryniewicz, A., Price, David, Moniuszko, M., Boasso, A., Edghill-Spano, Y., West, S. M., Venzon, D., Vaccari, M., Tsai, W.-P., Tryniszewska, E., Nacsa, J., Villinger, F., Ansari, A. A., Trindade, C. J., Morre, M., Brooks, D., Arlen, P., Brown, H. J., Kitchen, C. M. R., Zack, J. A., Douek, D. C., Shearer, G. M., Lewis, M. G., Koup, R. A. and Franchini, G. 2007. Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virusmac251-infected macaques. The Journal of Immunology 178 (6) , pp. 3492-3504. 10.4049/jimmunol.178.6.3492

Price, David, Silvestri, G., Brenchley, J.M. and Asher, T.W. 2006. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Medicine 12 (12) , pp. 1365-71. 10.1038/nm1511

Chattopadhyay, Pratip K., Price, David, Harper, Theresa F., Betts, Michael R., Yu, Joanne, Gostick, Emma, Perfetto, Stephen P., Goepfert, Paul, Koup, Richard A., De Rosa, Stephen C., Bruchez, Marcel P. and Roederer, Mario 2006. Quantum dot semiconductor nanocrystals for immunophenotyping by polychomatic flow cytometry. Nature Medicine 12 (8) , pp. 972-7. 10.1038/nm1371

Wooldridge, Linda, Scriba, Thomas J., Milicic, Anita, Laugel, Bruno Frederic, Gostick, Emma, Price, David, Phillips, Rodney E. and Sewell, Andrew 2006. Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers. European Journal of Immunology 36 (7) , pp. 1847-1855. 10.1002/eji.200635886

Casazza, Joseph P., Betts, Michael R., Price, David, Precopio, Melissa L., Ruff, Laura E., Brenchley, Jason M., Hill, Brenna J., Roederer, Mario, Douek, Daniel C. and Koup, Richard A. 2006. Acquisition of direct antiviral effector functions by CMV-specific CD4+T lymphocytes with cellular maturation. Journal of Experimental Medicine 203 (13) , pp. 2865-2877. 10.1084/jem.20052246
file

Venturi, V., Kedzierska, K., Price, David, Doherty, P. C., Douek, D. C., Turner, S. J. and Davenport, M. P. 2006. Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination. Proceedings of the National Academy of Sciences of the United States of America 103 (49) , pp. 18691-18696. 10.1073/pnas.0608907103
file

Leslie, A., Price, David, Mkhize, P., Bishop, K., Rathod, A., Day, C., Crawford, H., Honeyborne, I., Asher, T. E., Luzzi, G., Edwards, A., Rosseau, C. M., Mullins, J. I., Tudor-Williams, G., Novelli, V., Brander, C., Douek, D. C., Kiepiela, P., Walker, B. D. and Goulder, P. J. R. 2006. Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. The Journal of Immunology 177 (7) , pp. 4699-4708. 10.4049/jimmunol.177.7.4699

Petrovas, Constantinos, Casazza, Joseph P., Brenchley, Jason M., Price, David, Gostick, Emma, Adams, William C., Precopio, Melissa L., Schacker, Timothy, Roederer, Mario, Douek, Daniel C. and Koup, Richard A. 2006. PD-1 is a regulator of virus-specific CD8+T cell survival in HIV infection. Journal of Experimental Medicine 203 (10) , pp. 2281-2292. 10.1084/jem.20061496
file

Brenchley, J. M., Ruff, L. E., Casazza, J. P., Koup, R. A., Price, David and Douek, D. C. 2006. Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo. Journal of Virology 80 (14) , pp. 6801-6809. 10.1128/JVI.00070-06
file

Laugel, Bruno, Price, David and Sewell, Andrew K. 2006. On the path to TCR-directed therapeutics. Nature Biotechnology 24 (6) , pp. 615-616. 10.1038/nbt0606-615b

Scheinberg, Phillip, Price, David, Ambrozak, David R., Barrett, A. John and Douek, Daniel C. 2006. Alloreactive T cell clonotype recruitment in a mixed lymphocyte reaction: Implications for graft engineering. Experimental Hematology 34 (6) , pp. 788-795. 10.1016/j.exphem.2006.03.001

Kan-Mitchell, J., Bajcz, M., Schaubert, K. L., Price, David, Brenchley, J. M., Asher, T. E., Douek, D. C., Ng, H. L., Yang, O. O., Rinaldo, C. R., Benito, J. M., Bisikirska, B., Hegde, R., Marincola, F. M., Boggiano, C., Wilson, D., Abrams, J., Blondelle, S. E. and Wilson, D. B. 2006. Degeneracy and repertoire of the Human HIV-1 Gag p1777-85 CTL Response. The Journal of Immunology 176 (11) , pp. 6690-6701. 10.4049/jimmunol.176.11.6690

Brenchley, Jason M, Price, David and Douek, Daniel C 2006. HIV disease: fallout from a mucosal catastrophe? Nature Immunology 7 (3) , pp. 235-239. 10.1038/ni1316

Price, David, Brenchley, Jason M., Ruff, Laura E., Betts, Michael R., Hill, Brenna J., Roederer, Mario, Koup, Richard A., Migueles, Steven A., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew, Connors, Mark and Douek, Daniel C. 2005. Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. Journal of Experimental Medicine 202 (10) , pp. 1349-61. 10.1084/jem.20051357
file

Wooldridge, Linda, Berg, Hugo A. van den, Glick, Meir, Gostick, Emma, Laugel, Bruno Frederic, Hutchinson, Sarah L., Milicic, Anita, Brenchley, Jason M., Douek, Daniel C., Price, David and Sewell, Andrew 2005. Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface. The Journal of Biological Chemistry 280 (30) , pp. 27491-27501. 10.1074/jbc.M500555200

Laugel, B., Boulter, J. M., Lissin, N., Vuidepot, A., Gostick, E., Crotty, L. E., Douek, D. C., Hemelaar, J., Price, David, Jakobsen, B. and Sewell, Andrew K. 2005. Design of soluble recombinant T Cell receptors for antigen targeting and T cell inhibition. Journal of Biological Chemistry 280 (3) , pp. 1882-1892. 10.1074/jbc.M409427200

Milicic, A., Price, David, Zimbwa, P., Booth, B. L., Brown, H. L., Easterbrook, P. J., Olsen, K., Robinson, N., Gileadi, U., Sewell, A. K., Cerundolo, V. and Phillips, R. E. 2005. CD8+ T cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef. The Journal of Immunology 175 (7) , pp. 4618-4626. 10.4049/jimmunol.175.7.4618

Rezvani, K., Brenchley, J. M., Price, David, Kilical, Y., Gostick, E., Sewell, Andrew K., Li, J., Mielke, S., Douek, D. C. and Barrett, A. J. 2005. T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization. Clinical Cancer Research 11 (24) , pp. 8799-8807. 10.1158/1078-0432.CCR-05-1314

Joos, B., Trkola, A., Fischer, M., Kuster, H., Rusert, P., Leemann, C., Boni, J., Oxenius, A., Price, David, Phillips, R. E., Wong, J. K., Hirschel, B., Weber, R. and Gunthard, H. F. 2005. Low human immunodeficiency virus envelope diversity correlates with low in vitro replication capacity and predicts spontaneous control of plasma viremia after treatment interruptions. Journal of Virology 79 (14) , pp. 9026-9037. 10.1128/JVI.79.14.9026-9037.2005
file

Fujiwara, H., Melenhorst, J. J., El Ouriaghli, F., Kajigaya, S., Grube, M., Sconocchia, G., Rezvani, K., Price, David, Hensel, N. F., Douek, D. C. and Barrett, A. J. 2005. In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins. Clinical Cancer Research 11 (12) , pp. 4495-4503. 10.1158/1078-0432.CCR-04-2363

Betts, M. R., Exley, B., Price, David, Bansal, A., Camacho, Z. T., Teaberry, V., West, S. M., Ambrozak, D. R., Tomaras, G., Roederer, M., Kilby, J. M., Tartaglia, J., Belshe, R., Gao, F., Douek, D. C., Weinhold, K. J., Koup, R. A., Goepfert, P. and Ferrari, G. 2005. Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America 102 (12) , pp. 4512-4517. 10.1073/pnas.0408773102
file

Seggewiss, R., Lore, K., Greiner, E., Magnusson, M. K., Price, David, Douek, D. C., Dunbar, D. C. and Wiestner, A. 2005. Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. Blood 105 (6) , pp. 2473-2479. 10.1182/blood-2004-07-2527

Casazza, J. P., Betts, M. R., Hill, B. J., Brenchley, J. M., Price, David, Douek, D. C. and Koup, R. A. 2005. Immunologic pressure within class I-restricted cognate human immunodeficiency virus epitopes during highly active antiretroviral therapy. Journal of Virology 79 (6) , pp. 3653-3663. 10.1128/JVI.79.6.3653-3663.2005
file

Hewitt, R. E., Lissina, A., Green, A. E., Slay, E. S., Price, David and Sewell, Andrew K. 2005. The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins. Clinical and Experimental Immunology 139 (1) , pp. 101-111. 10.1111/j.1365-2249.2005.02665.x

Ellmerich, S., Mycko, M., Takacs, K., Waldner, H., Wahid, F. N., Boyton, R. J., King, R. H. M., Smith, P. A., Amor, S., Herlihy, A. H., Hewitt, R. E., Jutton, M., Price, David, Hafler, D. A., Kuchroo, V. K. and Altmann, D. M. 2005. High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model. The Journal of Immunology 174 (4) , pp. 1938-1946. 10.4049/jimmunol.174.4.1938

Price, David, West, Sadie M., Betts, Michael R., Ruff, Laura E., Brenchley, Jason M., Ambrozak, David R., Edghill-Smith, Yvette, Kuroda, Marcelo J., Bogdan, Derek, Kunstman, Kevin, Letvin, Norman L., Franchini, Genoveffa, Wolinsky, Steven M., Koup, Richard A. and Douek, Daniel C. 2004. T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 21 (6) , pp. 793-803. 10.1016/j.immuni.2004.10.010

Green, A. E., Lissina, A., Hutchinson, S. L., Hewitt, R. E., Temple, B., James, D., Boulter, J. M., Price, David and Sewell, Andrew K. 2004. Recognition of nonpeptide antigens by human Vγ9Vδ2 T cells requires contact with cells of human origin. Clinical & Experimental Immunology 136 (3) , pp. 472-482. 10.1111/j.1365-2249.2004.02472.x

Brenchley, J. M., Hill, B. J., Ambrozak, D. R., Price, David, Guenaga, F. J., Casazza, J. P., Kuruppu, J., Yazdani, J., Migueles, S. A., Connors, M., Roederer, M., Douek, D. C. and Koup, R. A. 2004. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. Journal of Virology 78 (3) , pp. 1160-1168. 10.1128/JVI.78.3.1160-1168.2004
file

Brenchley, Jason M., Schacker, Timothy W., Ruff, Laura E., Price, David, Taylor, Jodie H., Beilman, Gregory J., Nguyen, Phuong L., Khoruts, Alexander, Larson, Matthew, Haase, Ashley T. and Douek, Daniel C. 2004. CD4+T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. Journal of Experimental Medicine 200 (6) , pp. 749-759. 10.1084/jem.20040874
file

Scherer, A., Frater, J., Oxenius, A., Agudelo, J., Price, David, Gunthard, H. F., Barnardo, M., Perrin, L., Hirschel, B., Phillips, R. E. and McLean, A. R. 2004. Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS. Proceedings of the National Academy of Sciences of the United States of America 101 (33) , pp. 12266-12270. 10.1073/pnas.0404091101
file

Oxenius, Annette, Price, David, Trkola, Alexandra, Edwards, Charles, Gostick, Emma, Zhang, Hua-Tang, Easterbrook, Philippa J., Tun, Tin, Johnson, Andrew, Waters, Anele, Holmes, Edward C. and Phillips, Rodney E. 2004. Loss of viral control in early HIV-1 infection Is temporally associated with sequential escape from CD8+ T cell responses and decrease in HIV-1-specific CD4+ and CD8+ T cell frequencies. International Journal of Infectious Diseases 190 (4) , pp. 713-721. 10.1086/422760

Crawford, M. P., Yan, S., Ortega, S. B., Mehta, R. S., Hewitt, R. E., Price, David, Statsny, P., Douek, D. C., Koup, R. A., Racke, M. K. and Karandikar, N. J. 2004. High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood 103 (11) , pp. 4222-4231. 10.1182/blood-2003-11-4025

Betts, M. R., Price, David, Brenchley, J. M., Lore, K., Guenaga, F. J., Smed-Sorensen, A., Ambrozak, D. R., Migueles, S. A., Connors, M., Roederer, M., Douek, D. C. and Koup, R. A. 2004. The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration. The Journal of Immunology 172 (10) , pp. 6407-6417. 10.4049/jimmunol.172.10.6407

Fujiwara, H., El Ouriaghli, F., Grube, M., Price, David, Rezvani, K., Gostick, E., Sconocchia, G., Melenhorst, J., Hensel, N., Douek, D. C. and Barrett, A. J. 2004. Identification and in vitro expansion of CD4+ and CD8+ T cells specific for human neutrophil elastase. Blood 103 (8) , pp. 3076-3083. 10.1182/blood-2003-07-2424

Oxenius, Annette, Price, David, Hersberger, Martin, Schlaepfer, Erika, Weber, Rainer, Weber, Markus, Kundig, Thomas M., Böni, Jürg, Joller, Helen, Phillips, Rodney E., Flepp, Markus, Opravil, Milos and Speck, Roberto F. 2004. HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+T cells in relation to HIV RNA load. International Journal of Infectious Diseases 189 (7) , pp. 1199-1208. 10.1086/382028

Wooldridge, Linda, Hutchinson, Sarah L., Choi, Ed M., Lissina, Anna, Jones, Emma, Mirza, Fareed, Dunbar, P. Rod, Price, David, Cerundolo, Vincenzo and Sewell, Andrew 2003. Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface. J Immunol 171 , pp. 6650-60.

Jones, Emma, Price, David, Dahm-Vicker, Michaela, Cerundolo, Vincenzo, Klenerman, Paul and Gallimore, Awen 2003. The influence of macrophage inflammatory protein-1alpha on protective immunity mediated by antiviral cytotoxic T cells. Immunology 109 (1) , pp. 68-75. 10.1046/j.1365-2567.2003.01636.x

Price, David, Scullard, G., Oxenius, A., Braganza, R., Beddows, S. A., Kazmi, S., Clarke, J. R., Johnson, G. E., Weber, J. N. and Phillips, R. E. 2003. Discordant outcomes following failure of antiretroviral therapy are associated with substantial differences in human immunodeficiency virus-specific cellular immunity. Journal of Virology 77 (10) , pp. 6041-6049. 10.1128/JVI.77.10.6041-6049.2003

Brookes, Roger H., Pathan, Ansar A., McShane, Helen, Hensmann, Meike, Price, David and Hill, Adrian V. S. 2003. CD8+ T cell-mediated suppression of intracellularMycobacterium tuberculosis growth in activated human macrophages. European Journal of Immunology 33 (12) , pp. 3293-3302. 10.1002/eji.200324109

Betts, Michael R., Brenchley, Jason M., Price, David, De Rosa, Stephen C., Douek, Daniel C., Roederer, Mario and Koup, Richard A. 2003. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. Journal of Immunological Methods 281 (1-2) , pp. 65-78. 10.1016/S0022-1759(03)00265-5

Rezvani, K., Grube, M., Benchley, J. M., Sconocchia, G., Fujiwara, H., Price, David, Gostick, E., Yamada, K., Melenhorst, J., Childs, R., Hensel, N., Douek, D. C. and Barrett, A. J. 2003. Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. Blood 102 (8) , pp. 2892-2900. 10.1182/blood-2003-01-0150

Hutchinson, S. L., Wooldridge, L., Tafuro, S., Laugel, B., Glick, M., Boulter, J. M., Jakobsen, B. K., Price, David and Sewell, A. K. 2003. The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. Journal of Biological Chemistry 278 (27) , pp. 24285-24293. 10.1074/jbc.M300633200
file

Fagard, C., Oxenius, A., Günthard, H., Garcia, F., Le Braz, M., Mestre, G., Battegay, M., Furrer, H., Vernazza, P., Bernasconi, E., Telenti, A., Weber, R., Leduc, D., Yerly, S., Price, David, Dawson, S., Klimkait, T., Perneger, T. V., McLean, A., Clotet, B., Gatell, J. M., Perrin, L., Plana, M., Phillips, R. and Hirschel, B. 2003. A prospective trial of structured treatment interruptions in human immunodeficiency virus infection. Archives of Internal Medicine 163 (10) , pp. 1220-1226. 10.1001/archinte.163.10.1220
file

Oxenius, A., Price, David, Gunthard, H. F., Dawson, S. J., Fagard, C., Perrin, L., Fischer, M., Weber, R., Plana, M., Garcia, F., Hirschel, B., McLean, A. and Phillips, R. E. 2002. Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proceedings of the National Academy of Sciences of the United States of America 99 (21) , pp. 13747-13752. 10.1073/pnas.202372199

Oxenius, A., McLean, A. R., Fischer, M., Price, David, Dawson, S. J., Hafner, R., Schneider, C., Joller, H., Hirschel, B., Phillips, R. E., Weber, R. and Gunthard, H. F. 2002. Human Immunodeficiency Virus-specific CD8+ T-Cell responses do not predict viral growth and clearance rates during structured intermittent antiretroviral therapy. Journal of Virology 76 (20) , pp. 10169-10176. 10.1128/JVI.76.20.10169-10176.2002

Glick, M., Price, David, Vuidepot, A.-L., Andersen, T. B., Hutchinson, S. L., Laugel, B., Sewell, Andrew K., Boulter, J. M., Dunbar, P. R., Cerundolo, V., Oxenius, A., Bell, J. I., Richards, W. G. and Jakobsen, B. K. 2002. Novel CD8+ T cell antagonists based on 2-Microglobulin. Journal of Biological Chemistry 277 (23) , pp. 20840-20846. 10.1074/jbc.M201819200

Douek, Daniel C., Brenchley, Jason M., Betts, Michael R., Ambrozak, David R., Hill, Brenna J., Okamoto, Yukari, Casazza, Joseph P., Kuruppu, Janaki, Kunstman, Kevin, Wolinsky, Steven, Grossman, Zvi, Dybul, Mark, Oxenius, Annette, Price, David, Connors, Mark and Koup, Richard A. 2002. HIV preferentially infects HIV-specific CD4+ T cells. Nature 417 (6884) , pp. 95-98. 10.1038/417095a

Kelleher, Anthony D., Sewell, Andrew K. and Price, David 2002. Dyslipidemia due to retroviral protease inhibitors [Letter]. Nature Medicine 8 (4) , p. 308. 10.1038/nm0402-308a

Altes, Hester Korthals, Price, David and Jansen, Vincent A.A. 2001. Effector cytotoxic T lymphocyte numbers induced by vaccination should exceed levels in chronic infection for protection from HIV. Vaccine 20 (1-2) , pp. 3-6. 10.1016/S0264-410X(01)00318-8

Oxenius, Annette, Price, David, Dawson, Sara J., Tun, Tin, Easterbrook, Philippa J., Phillips, Rodney E. and Sewell, Andrew K. 2001. Cross-staining of cytotoxic T lymphocyte populations with peptide-MHC class I multimers of natural HIV-1 variant antigens. AIDS 15 (1) , pp. 121-122. 10.1097/00002030-200101050-00018

Purbhoo, M. A., Boulter, J. M., Price, David, Vuidepot, A.-L., Hourigan, C. S., Dunbar, P. R., Olson, K., Dawson, S. J., Phillips, R. E., Jakobsen, B. K., Bell, J. I. and Sewell, Andrew K. 2001. The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor chain. Journal of Biological Chemistry 276 (35) , pp. 32786-32792. 10.1074/jbc.M102498200

Karadimitris, A., Gadola, S., Altamirano, M., Brown, D., Woolfson, A., Klenerman, P., Chen, J.-L., Koezuka, Y., Roberts, I. A. G., Price, David, Dusheiko, G., Milstein, C., Fersht, A., Luzzatto, L. and Cerundolo, V. 2001. Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography. Proceedings of the National Academy of Sciences of the United States of America 98 (6) , pp. 3294-3298. 10.1073/pnas.051604498

Sewell, Andrew K. and Price, David 2001. Dendritic cells and transmission of HIV-1. Trends in Immunology 22 (4) , pp. 173-175. 10.1016/S1471-4906(01)01866-X

Phillips, Rodney E, Oxenius, Annette, Price, David and Bangham, Charles R.M 2000. AIDS: the evolving story. Trends in Microbiology 8 (4) , pp. 147-148. 10.1016/S0966-842X(00)01706-6

Oxenius, A., Price, David, Easterbrook, P. J., O'Callaghan, C. A., Kelleher, A. D., Whelan, J. A., Sontag, G., Sewell, Andrew K. and Phillips, R. E. 2000. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America 97 (7) , pp. 3382-3387. 10.1073/pnas.97.7.3382

Price, David, Klenerman, Paul, Booth, Bruce L, Phillips, Rodney E and Sewell, Andrew K 1999. Cytotoxic T lymphocytes, chemokines and antiviral immunity. Immunology Today 20 (5) , pp. 212-216. 10.1016/S0167-5699(99)01447-4

Sewell, Andrew K., Gerth, U. C., Price, David, Purbhoo, M. A., Boulter, J. M., Gao, G. F., Bell, J. I., Phillips, R. E. and Jakobsen, B. K. 1999. Antagonism of cytotoxic T-lymphocyte activation by soluble CD8. Nature Medicine 5 , pp. 399-404. 10.1038/7398

Lewis, J. W., Sewell, Andrew K., Price, David and Elliot, T. 1998. HLA-A*0201 presents TAP-dependent peptide epitopes to cytotoxic T lymphocytes in the absence of tapasin. European Journal of Immunology 28 , pp. 3214-3220.

Price, David, Sewell, Andrew K., Dong, Tao, Tan, Rusung, Goulder, Philip J. R., Rowland-Jones, Sarah L. and Phillips, Rodney E. 1998. Antigen-specific release of b-chemokines by anti-HIV-1 cytotoxic T lymphocytes. Current Biology 8 (6) , pp. 355-358. 10.1016/S0960-9822(98)70138-1

Goulder, Philip, Price, David, Nowak, Martin, Rowland-Jones, Sarah, Phillips, Rodney and McMichael, Andrew 1997. Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses. Immunological Reviews 159 (1) , pp. 17-29. 10.1111/j.1600-065X.1997.tb01004.x

Sewell, Andrew K., Harcourt, Gillian C., Goulder, Philip J. R., Price, David and Phillips, Rodney E. 1997. Antagonism of cytotoxic T lymphocyte-mediated lysis by natural HIV-1 altered peptide ligands requires simultaneous presentation of agonist and antagonist peptides. European Journal of Immunology 27 (9) , pp. 2323-2329. 10.1002/eji.1830270929

Goulder, Philip J. R., Reid, Scott W., Price, David, O'Callaghan, Chris A., McMichael, Andrew J., Phillips, Rodney E. and Jones, E. Yvonne 1997. Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes. European Journal of Immunology 27 (6) , pp. 1515-1521. 10.1002/eji.1830270630

Price, David, PJ, Goulder, P, Klenerman, Sewell, Andrew, PJ, Easterbrook, M, Troop, CR, Bangham and RE, Phillips 1997. Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection. Proceedings of the National Academy of Sciences 94 (5) , pp. 1890-1895. 10.1073/pnas.94.5.1890
file

Goulder, P.J.R., Sewell, A.K., Lalloo, D.G., Price, David, Whelan, J.A., Evans, J., Taylor, G.P., Luzzi, G., Giangrande, P., Phillips, R.E. and McMichael, A.J. 1997. Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation. Journal of Experimental Medicine 185 (8) , pp. 1423-1433. 10.1084/jem.185.8.1423
file

Teare, Julian P., Price, David, Foster, Graham R., McBride, Michael, Goldin, Robert D. and Main, Janice 1995. Reversible AIDS-related sclerosing cholangitis. Journal of Hepatology 23 (2) , pp. 209-211. 10.1016/0168-8278(95)80337-8

Price, David, Hollings, N. P., Janes, S. M., Main, J. and Coker, R. J. 1994. Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole. Journal of Antimicrobial Chemotherapy 34 (2) , p. 303. 10.1093/jac/34.2.303

This list was generated on Thu Dec 12 09:12:12 2019 GMT.