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Number of items: 21.

Pepper, Christopher John, Majid, Aneela, Lin, Thet Thet, Hewamana, Saman, Pratt, Guy, Walewska, Renata, Gesk, Stefan, Siebert, Reiner, Wagner, Simon, Kennedy, Ben, Miall, Fiona, Davis, Zadie A., Tracy, Ian, Gardiner, Anne C., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Dyer, Martin J. S., Oscier, David and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621 2012. Defining the prognosis of early stage chronic lymphocytic leukaemia patients. British Journal of Haematology 156 (4) , pp. 499-507. 10.1111/j.1365-2141.2011.08974.x

Majid, Aneela, Lin, Thet Thet, Best, Giles, Fishlock, Keith, Hewamana, Saman, Pratt, Guy, Yallop, Deborah, Buggins, Andrea G. S., Wagner, Simon, Kennedy, Ben J., Miall, Fiona, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Devereux, Stephen, Oscier, David G., Dyer, Martin J. S., Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621 and Pepper, Christopher John 2011. CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL. Leukemia Research 35 (6) , pp. 750-756. 10.1016/j.leukres.2010.10.022

Jenkins, Christopher, Hewamana, Saman, Krige, David, Pepper, Christopher John and Burnett, Alan Kenneth 2011. Aminopeptidase inhibition by the novel agent CHR-2797 (tosedostat) for the therapy of acute myeloid leukemia. Leukemia Research 35 (5) , pp. 677-681. 10.1016/j.leukres.2010.10.030

Pepper, Christopher John, Mahdi, J. G., Buggins, A. G. S., Hewamana, Saman, Walsby, Elisabeth Jane ORCID: https://orcid.org/0000-0001-8523-5017, Mahdi, Eamon, Al-Haza'a, A., Mahdi, Ali J., Lin, Thet Thet, Pearce, Laurence, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Bowen, Ivor D., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621 2011. Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2. Cell Proliferation 44 (4) , pp. 380-390. 10.1111/j.1365-2184.2011.00760.x

Buggins, Andrea G. S., Pepper, Christopher John, Patten, Piers E. M., Hewamana, Saman, Gohil, Satyen, Moorhead, Jane, Folarin, Najeem'deen, Yallop, Deborah, Thomas, N. Shaun B., Mufti, Ghulam J., Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621 and Devereux, Stephen 2010. Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cells via NF-κB activation and De novo gene transcription. Cancer Research 70 (19) , pp. 7523-7534. 10.1158/0008-5472.CAN-10-1634

Lin, Thet Thet, Letsolo, Boitelo Theresiah, Robinson, Rhiannon Elizabeth, Rowson, Janet Maud, Pratt, Guy, Hewamana, Saman, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 2010. Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis. Blood 116 (11) , pp. 1899-1907. 10.1182/blood-2010-02-272104

Pearce, Laurence, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Lin, Thet Thet, Hewamana, Saman, Matthews, Reginald James, Deaglio, Silvia, Rowntree, Clare, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 2010. Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38. Haematologica 95 (3) , pp. 514-517. 10.3324/haematol.2009.014381

Walsby, Elisabeth Jane ORCID: https://orcid.org/0000-0001-8523-5017, Pratt, G., Hewamana, Saman, Crooks, P. A., Burnett, Alan Kenneth, Fegan, Christopher Daniel. ORCID: https://orcid.org/0000-0001-9685-0621 and Pepper, Christopher John 2010. The NF- B inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib. Molecular Cancer Therapeutics 9 (6) , pp. 1574-1582. 10.1158/1535-7163.MCT-10-0104

Pepper, Christopher John, Hewamana, Saman, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621 2009. NF-κB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia. Future Oncology 5 (7) , pp. 1027-1037. 10.2217/fon.09.72

Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Shore, Angharad M., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Hewamana, Saman, Jones, Catrin M., Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Brewis, Ian Andrew 2009. Quantitative nuclear proteomics reveals new phenotypes altered in lymphoblastoid cells. Proteomics - Clinical Applications 3 (3) , pp. 359-369. 10.1002/prca.200800137

Hewamana, Saman, Lin, Thet Thet, Rowntree, Clare, Karunanithi, Kamaraj, Pratt, Guy, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Pepper, Christopher John 2009. Rel A is an independent biomarker of clinical outcome in chronic lymphocytic leukemia. Journal of Clinical Oncology 27 (5) , pp. 763-769. 10.1200/JCO.2008.19.1114

Hewamana, Saman, Pepper, Christopher John, Karunanithi, Kamaraj, Jenkins, Christopher and Rowntree, Clare 2009. Durable response to a single dose of Anti D in immune thrombocytopenic purpura in an adult with underlying human immunodeficiency viral infection [Letter]. Annals of Hematology 88 (11) , pp. 1155-1156. 10.1007/s00277-009-0744-4

Hewamana, Saman, Pepper, Christopher John, Jenkins, Chris and Rowntree, Clare 2009. Acute renal failure as the presenting feature of leukaemic infiltration in chronic lymphocytic leukaemia. Clinical and Experimental Nephrology 13 (2) , pp. 179-181. 10.1007/s10157-009-0129-y

Hewamana, Saman, Lin, Thet Thet, Jenkins, Chris, Burnett, Alan Kenneth, Jordan, Craig T., Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Rowntree, Clare and Pepper, Christopher John 2008. The novel nuclear factor- B inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine. Clinical Cancer Research 14 (24) , pp. 8102-8111. 10.1158/1078-0432.CCR-08-1673

Pepper, Christopher John, Lin, Thet Thet, Pratt, Guy, Hewamana, Saman, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Hiller, Louise, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Ward, Rachel, Starczynski, Jane, Austen, Belinda, Hooper, Laura, Stankovic, Tatjana and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621 2008. Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 112 (9) , pp. 3807-3817. 10.1182/blood-2008-05-157131

Hewamana, Saman, Alghazal, Suhair Alkailani, Lin, Thet Thet, Clement, Matthew ORCID: https://orcid.org/0000-0002-9280-5281, Jenkins, Christopher, Guzman, Monica L., Jordan, Craig T., Neelakantan, Sundar, Crooks, Peter A., Burnett, Alan Kenneth, Pratt, Guy, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Rowntree, Clare, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Pepper, Christopher John 2008. The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target. Blood 111 (9) , pp. 4681-4689. 10.1182/blood-2007-11-125278

Lin, Thet Thet, Hewamana, Saman, Ward, Rachel Mary, Taylor, Hannah, Payne, Tammy, Pratt, Guy, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Fegan, Christopher D. ORCID: https://orcid.org/0000-0001-9685-0621 and Pepper, Christopher John 2008. Highly purified CD38+ sub-populations show no evidence of preferential clonal evolution despite having increased proliferative activity when compared with CD38+ sub-populations derived from the same chronic lymphocytic leukaemia patient. British Journal of Haematology 142 (4) , pp. 595-605. 10.1111/j.1365-2141.2008.07236.x

Hewamana, Saman, Pepper, Christopher John, Couzens, Stephen, Thomas, Alun and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2008. IgM multiple myeloma: a diagnostic challenge in a patient with coexisting chronic lymphocytic leukaemia. International Journal of Hematology 88 (4) , pp. 424-427. 10.1007/s12185-008-0179-z

Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Donev, Rossen Mintchev and Hewamana, Saman 2008. Targeting transcription factors for therapeutic benefit. Molecular Biosystems 4 (9) , pp. 909-919. 10.1039/b801920g

Jenkins, Christopher, Hewamana, Saman, Gilkes, Amanda F., Neelakantan, Sundar, Crooks, Peter, Mills, Ken, Pepper, Christopher John and Burnett, Alan Kenneth 2008. Nuclear factor-kappaB as a potential therapeutic target for the novel cytotoxic agent LC-1 in acute myeloid leukaemia. British Journal of Haematology 143 (5) , pp. 661-671. 10.1111/j.1365-2141.2008.07392.x

Hewamana, Saman. 2008. Prospective analysis of NF-kappaB as a superior prognostic marker in chronic lymphocytic leukaemia. PhD Thesis, Cardiff University.
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