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Number of items: 22.

Derudas, Marco, Vanpouille, Christophe, Carta, Davide, Zicari, Sonia, Andrei, Graciela, Snoeck, Robert, Brancale, Andrea, Margolis, Leonid, Balzarini, Jan and McGuigan, Christopher 2017. Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis, and biological evaluation of new acyclic nucleoside protides. Journal of Medicinal Chemistry 60 (18) , pp. 7876-7896. 10.1021/acs.jmedchem.7b01009

McGuigan, Christopher, Serpi, Michaela, Slusarczyk, Magdalena, Ferrari, Valentina, Pertusati, Fabrizio, Meneghesso, Silvia, Derudas, Marco, Farleigh, Laura, Zanetta, Paola and Bugert, Joachim 2016. Anti-flavivirus activity of different tritylated pyrimidine and purine nucleoside analogues. ChemistryOpen 5 (3) , pp. 227-235. 10.1002/open.201500216

Toti, Kiran S., Derudas, Marco, Pertusati, Fabrizio, Sinnaeve, Davy, Van den Broeck, Freya, Margamuljana, Lia, Martins, José C., Herdewijn, Piet, Balzarini, Jan, McGuigan, Christopher and Van Calenbergh, Serge 2014. Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity. Journal of Organic Chemistry 79 (11) , pp. 5097-5112. 10.1021/jo500659e

McGuigan, Christopher, Derudas, Marco, Gonczy, Blanka, Hinsinger, Karen, Kandil, Sahar, Pertusati, Fabrizio, Serpi, Michaela, Snoeck, Robert, Andrei, Graciela, Balzarini, Jan, McHugh, Timothy D., Maitra, Arundhati, Akorli, Ernest, Evangelopoulos, Dimitrios and Bhakta, Sanjib 2014. ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents. Bioorganic and Medicinal Chemistry 22 (9) , pp. 2816-2824. 10.1016/j.bmc.2014.02.056

McGuigan, Christopher, Bourdin, Claire, Derudas, Marco, Hamon, Nadege, Hinsinger, Karen, Kandil, Sahar, Madela, Karolina, Meneghesso, Silvia, Pertusati, Fabrizio, Serpi, Michaela, Slusarczyk, Magdalena, Chamberlain, Stanley, Kolykhalov, Alexander, Vernachio, John, Vanpouille, Christophe, Introini, Andrea, Margolis, Leonid and Balzarini, Jan 2013. Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides. European Journal of Medicinal Chemistry 70 , pp. 326-340. 10.1016/j.ejmech.2013.09.047

Vanpouille, Christopher, Lisco, Andrea, Introini, Andrea, Grivel, Jean-Charles, Munawwar, Arshi, Merbah, Melanie, Schinazi, Raymond F., Derudas, Marco, McGuigan, Christopher, Balzarini, Jan and Margolis, Leonid 2012. Exploiting the Anti-HIV-1 activity of acyclovir: Suppression of primary and drug-resistant HIV isolates and potentiation of the activity by Ribavirin. Antimicrobial Agents and Chemotherapy 56 (5) , pp. 2604-2611. 10.1128/AAC.05986-11

Derudas, Marco and McGuigan, Christopher 2012. Serendipity and VZV drug discovery. Drug Discovery Today: Technologies 9 (3) , e177-e181. 10.1016/j.ddtec.2011.11.001

Toti, K. S., Derudas, Marco, McGuigan, Christopher, Balzarini, J and Van Calenbergh, S 2011. Synthesis and antiviral evaluation of α-l-2'-deoxythreofuranosyl nucleosides. European Journal of Medicinal Chemistry

Vanpouille, C., Lisco, A., Derudas, Marco, Saba, E., Grivel, J. C., Brichacek, B., Scrimieri, F., Schinazi, R., Schols, D., McGuigan, Christopher, Balzarini, J. and Margolis, L. 2010. A New Class of Dual-Targeted Antivirals: Monophosphorylated Acyclovir Prodrug Derivatives Suppress Both Human Immunodeficiency Virus Type 1 and Herpes Simplex Virus Type 2. International Journal of Infectious Diseases 201 (4) , pp. 635-643. 10.1086/650343

Derudas, Marco, Brancale, Andrea, Naesens, L., Neyts, J., Balzarini, J. and McGuigan, Christopher 2010. Application of the phosphoramidate ProTide approach to the antiviral drug ribavirin. Bioorganic & Medicinal Chemistry 18 (7) , pp. 2748-2755. 10.1016/j.bmc.2010.02.015

Derudas, Marco, Quintiliani, Maurizio, Brancale, Andrea, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan and McGuigan, Christopher 2010. Evaluation of novel phosphoramidate ProTides of the 2′-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue. Antiviral Chemistry and Chemotherapy 21 (1) , pp. 15-31. 10.3851/IMP1661

McGuigan, Christopher, Derudas, Marco, Quintiliani, Maurizio, Andrei, Graciela, Snoeck, Robert, Henson, Geoffrey and Balzarini, Jan 2009. 2 '-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Biorganic and Medicinal Chemistry Letters 19 (22) , pp. 6264-6267. 10.1016/j.bmcl.2009.09.116

Derudas, Marco, Carta, Davide, Brancale, Andrea, Vanpouille, Christophe, Lisco, Andrea, Margolis, Leonid, Balzarini, Jan and McGuigan, Christopher 2009. The application of phosphoramidate ProTide technology to acyclovir confers anti-HIV inhibition. Journal of Medicinal Chemistry 52 (17) , pp. 5520-5530. 10.1021/jm9007856

Derudas, Marco, McGuigan, Christopher, Brancale, Andrea, Margolis, L. and Balzarini, J. 2009. The Application of Phosphoramidate Protide Technology to Acyclovir confers Novel Anti-HIV Inhibition. Antiviral Research 82 (2) , A57. 10.1016/j.antiviral.2009.02.134

Derudas, Marco, Quintiliani, Maurizio, McGuigan, Christopher, Brancale, Andrea, Henson, G. and Balzarini, J. 2009. Design, Synthesis, and Biological Evaluation of Novel Fluoro Derivatives of BCNA. Antiviral Research 82 (2) , A57. 10.1016/j.antiviral.2009.02.135

Tchesnokov, E. P., Obikhod, A., Massud, I., Lisco, A., Vanpouille, C., Brichacek, B., Balzarini, J., McGuigan, Christopher, Derudas, Marco, Margolis, L., Schinazi, R. F. and Gotte, M. 2009. Mechanisms Associated with HIV-1 Resistance to Acyclovir by the V75I Mutation in Reverse Transcriptase. Journal of Biological Chemistry 284 (32) , pp. 21496-21504. 10.1074/jbc.M109.024026

McGuigan, Christopher, Bidet, O., Derudas, Marco, Andrei, G., Snoeck, R. and Balzarini, J. 2009. Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus. Biorganic and Medicinal Chemistry 17 (8) , pp. 3025-3027. 10.1016/j.bmc.2009.03.022

Lisco, Andrea, Vanpouille, Christophe, Tchesnokov, Egor P., Grivel, Jean Charles, Biancotto, Angélique, Brichacek, Beda, Elliott, Julie, Fromentin, Emilie, Shattock, Robert, Anton, Peter, Gorelick, Robert, Balzarini, Jan, McGuigan, Christopher, Derudas, Marco, Gotte, Matthias, Schinazi, Raymond F. and Margolis, Leonid. 2008. Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues. Cell Host & Microbe 4 (3) , pp. 260-270. 10.1016/j.chom.2008.07.008

Derudas, Marco, McGuigan, Christopher, Brancale, Andrea, Neyts, J. and Balzarini, J. 2008. Application of the phosphoramidate protide approach to the antiviral drug ribavirin. Antiviral Research 78 (2) , 55. 10.1016/j.antiviral.2008.01.115

McGuigan, Christopher, Derudas, Marco, Bugert, Joachim Jakob, Andrei, G., Snoeck, R. and Balzarini, J. 2008. Successful kinase bypass with new acyclovir phosphoramidate prodrugs. Biorganic and Medicinal Chemistry Letters 18 (15) , pp. 4364-4367. 10.1016/j.bmcl.2008.06.069

Derudas, Marco, McGuigan, Christopher, Brancale, Andrea, Bugert, Joachim Jakob, Andrei, G., Snoeck, R. and Balzarini, J. 2008. Design, synthesis and biological evaluation of novel acyclovir ProTides. Antiviral Research 78 (2) , A55-A56. 10.1016/j.antiviral.2008.01.116

Derudas, Marco, McGuigan, Christopher, Snoeck, R., Andrei, G., De Clercq, E. and Balzarini, J. 2007. Design, synthesis, and biological evaluation of novel anti-VZV agents. Antiviral Research 74 (3) , A72. 10.1016/j.antiviral.2007.01.116

This list was generated on Thu Jul 9 06:32:25 2020 BST.