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Number of items: 22.

Derudas, Marco, Vanpouille, Christophe, Carta, Davide, Zicari, Sonia, Andrei, Graciela, Snoeck, Robert, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Margolis, Leonid, Balzarini, Jan and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2017. Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis, and biological evaluation of new acyclic nucleoside protides. Journal of Medicinal Chemistry 60 (18) , pp. 7876-7896. 10.1021/acs.jmedchem.7b01009
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McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Slusarczyk, Magdalena ORCID: https://orcid.org/0000-0002-4707-7190, Ferrari, Valentina ORCID: https://orcid.org/0000-0003-1895-8906, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Meneghesso, Silvia, Derudas, Marco, Farleigh, Laura, Zanetta, Paola and Bugert, Joachim ORCID: https://orcid.org/0000-0002-0556-3211 2016. Anti-flavivirus activity of different tritylated pyrimidine and purine nucleoside analogues. ChemistryOpen 5 (3) , pp. 227-235. 10.1002/open.201500216
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Toti, Kiran S., Derudas, Marco, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Sinnaeve, Davy, Van den Broeck, Freya, Margamuljana, Lia, Martins, José C., Herdewijn, Piet, Balzarini, Jan, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Van Calenbergh, Serge 2014. Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity. Journal of Organic Chemistry 79 (11) , pp. 5097-5112. 10.1021/jo500659e
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McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Derudas, Marco, Gonczy, Blanka, Hinsinger, Karen, Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Snoeck, Robert, Andrei, Graciela, Balzarini, Jan, McHugh, Timothy D., Maitra, Arundhati, Akorli, Ernest, Evangelopoulos, Dimitrios and Bhakta, Sanjib 2014. ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents. Bioorganic and Medicinal Chemistry 22 (9) , pp. 2816-2824. 10.1016/j.bmc.2014.02.056
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McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Bourdin, Claire, Derudas, Marco, Hamon, Nadege, Hinsinger, Karen, Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Madela, Karolina, Meneghesso, Silvia, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Slusarczyk, Magdalena ORCID: https://orcid.org/0000-0002-4707-7190, Chamberlain, Stanley, Kolykhalov, Alexander, Vernachio, John, Vanpouille, Christophe, Introini, Andrea, Margolis, Leonid and Balzarini, Jan 2013. Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides. European Journal of Medicinal Chemistry 70 , pp. 326-340. 10.1016/j.ejmech.2013.09.047
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Vanpouille, Christopher, Lisco, Andrea, Introini, Andrea, Grivel, Jean-Charles, Munawwar, Arshi, Merbah, Melanie, Schinazi, Raymond F., Derudas, Marco, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Balzarini, Jan and Margolis, Leonid 2012. Exploiting the Anti-HIV-1 activity of acyclovir: Suppression of primary and drug-resistant HIV isolates and potentiation of the activity by Ribavirin. Antimicrobial Agents and Chemotherapy 56 (5) , pp. 2604-2611. 10.1128/AAC.05986-11
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Derudas, Marco and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2012. Serendipity and VZV drug discovery. Drug Discovery Today: Technologies 9 (3) , e177-e181. 10.1016/j.ddtec.2011.11.001

Toti, K. S., Derudas, Marco, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Balzarini, J and Van Calenbergh, S 2011. Synthesis and antiviral evaluation of α-l-2'-deoxythreofuranosyl nucleosides. European Journal of Medicinal Chemistry

Derudas, Marco, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Naesens, L., Neyts, J., Balzarini, J. and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2010. Application of the phosphoramidate ProTide approach to the antiviral drug ribavirin. Bioorganic & Medicinal Chemistry 18 (7) , pp. 2748-2755. 10.1016/j.bmc.2010.02.015

Vanpouille, C., Lisco, A., Derudas, Marco, Saba, E., Grivel, J. C., Brichacek, B., Scrimieri, F., Schinazi, R., Schols, D., McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Balzarini, J. and Margolis, L. 2010. A New Class of Dual-Targeted Antivirals: Monophosphorylated Acyclovir Prodrug Derivatives Suppress Both Human Immunodeficiency Virus Type 1 and Herpes Simplex Virus Type 2. International Journal of Infectious Diseases 201 (4) , pp. 635-643. 10.1086/650343

Derudas, Marco, Quintiliani, Maurizio, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2010. Evaluation of novel phosphoramidate ProTides of the 2′-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue. Antiviral Chemistry and Chemotherapy 21 (1) , pp. 15-31. 10.3851/IMP1661

McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Derudas, Marco, Quintiliani, Maurizio, Andrei, Graciela, Snoeck, Robert, Henson, Geoffrey and Balzarini, Jan 2009. 2 '-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Biorganic and Medicinal Chemistry Letters 19 (22) , pp. 6264-6267. 10.1016/j.bmcl.2009.09.116

Derudas, Marco, Carta, Davide, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Vanpouille, Christophe, Lisco, Andrea, Margolis, Leonid, Balzarini, Jan and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2009. The application of phosphoramidate ProTide technology to acyclovir confers anti-HIV inhibition. Journal of Medicinal Chemistry 52 (17) , pp. 5520-5530. 10.1021/jm9007856

Derudas, Marco, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Margolis, L. and Balzarini, J. 2009. The Application of Phosphoramidate Protide Technology to Acyclovir confers Novel Anti-HIV Inhibition. Antiviral Research 82 (2) , A57. 10.1016/j.antiviral.2009.02.134

Derudas, Marco, Quintiliani, Maurizio, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Henson, G. and Balzarini, J. 2009. Design, Synthesis, and Biological Evaluation of Novel Fluoro Derivatives of BCNA. Antiviral Research 82 (2) , A57. 10.1016/j.antiviral.2009.02.135

McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Bidet, O., Derudas, Marco, Andrei, G., Snoeck, R. and Balzarini, J. 2009. Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus. Biorganic and Medicinal Chemistry 17 (8) , pp. 3025-3027. 10.1016/j.bmc.2009.03.022

Tchesnokov, E. P., Obikhod, A., Massud, I., Lisco, A., Vanpouille, C., Brichacek, B., Balzarini, J., McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Derudas, Marco, Margolis, L., Schinazi, R. F. and Gotte, M. 2009. Mechanisms Associated with HIV-1 Resistance to Acyclovir by the V75I Mutation in Reverse Transcriptase. Journal of Biological Chemistry 284 (32) , pp. 21496-21504. 10.1074/jbc.M109.024026

Lisco, Andrea, Vanpouille, Christophe, Tchesnokov, Egor P., Grivel, Jean Charles, Biancotto, Angélique, Brichacek, Beda, Elliott, Julie, Fromentin, Emilie, Shattock, Robert, Anton, Peter, Gorelick, Robert, Balzarini, Jan, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Derudas, Marco, Gotte, Matthias, Schinazi, Raymond F. and Margolis, Leonid. 2008. Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues. Cell Host & Microbe 4 (3) , pp. 260-270. 10.1016/j.chom.2008.07.008

Derudas, Marco, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Neyts, J. and Balzarini, J. 2008. Application of the phosphoramidate protide approach to the antiviral drug ribavirin. Antiviral Research 78 (2) , 55. 10.1016/j.antiviral.2008.01.115

Derudas, Marco, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Bugert, Joachim Jakob ORCID: https://orcid.org/0000-0002-0556-3211, Andrei, G., Snoeck, R. and Balzarini, J. 2008. Design, synthesis and biological evaluation of novel acyclovir ProTides. Antiviral Research 78 (2) , A55-A56. 10.1016/j.antiviral.2008.01.116

McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Derudas, Marco, Bugert, Joachim Jakob ORCID: https://orcid.org/0000-0002-0556-3211, Andrei, G., Snoeck, R. and Balzarini, J. 2008. Successful kinase bypass with new acyclovir phosphoramidate prodrugs. Biorganic and Medicinal Chemistry Letters 18 (15) , pp. 4364-4367. 10.1016/j.bmcl.2008.06.069

Derudas, Marco, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Snoeck, R., Andrei, G., De Clercq, E. and Balzarini, J. 2007. Design, synthesis, and biological evaluation of novel anti-VZV agents. Antiviral Research 74 (3) , A72. 10.1016/j.antiviral.2007.01.116

This list was generated on Tue Apr 23 08:56:04 2024 BST.


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