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Number of items: 16.

Hole, Paul Spencer, Zabkiewicz, Joanna, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul Charles, Marquez, Nuria, Hills, Robert Kerrin, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2013. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 122 (19) , pp. 3322-3330. 10.1182/blood-2013-04-491944

Morgan, Rhys G., Pearn, Lorna, Liddiard, Kate, Pumford, Sara Louise, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2013. γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia 27 (2) , pp. 336-343. 10.1038/leu.2012.221
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Zabkiewicz, Joanna, Pearn, Lorna, Hills, Robert Kerrin, Morgan, Rhys G., Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2010. PDK1 overexpression in acute myeloid leukemia; Clinical significance and potential as a therapeutic target [Abstract]. Blood 116 (21) , pp. 892-893.

Morgan, Rhys Gareth, Pearn, Lorna, Liddiard, Kate, Hills, Robert Kerrin, Burnett, Alan Kenneth, Tonks, Alex and Darley, Richard Lawrence 2010. Distinct regulation of beta- and gamma-Catenin throughout hematopoietic development contrasts with their cooperative roles in acute myeloid leukemia [Abstract]. Blood 116 (21) , 1573.

Hole, Paul Spencer, Pearn, Lorna, Tonks, Amanda Jayne, James, Philip Eurig, Burnett, Alan Kenneth, Darley, Richard Lawrence and Tonks, Alex 2010. Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells. Blood 115 (6) , pp. 1238-1246. 10.1182/blood-2009-06-222869

Tonks, Alex, Pearn, Lorna, Musson, Megan, Gilkes, Amanda F., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2007. Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia. Leukemia 21 (12) , pp. 2495-2505. 10.1038/sj.leu.2404961

Pearn, Lorna, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence 2007. The role of PKC and PDK1 in monocyte lineage specification by Ras. Blood 109 (10) , pp. 4461-9. 10.1182/blood-2006-09-047217

Tonks, Alex, Pearn, Lorna, Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence 2006. The sensitivity of human cells expressing RUNX1-RUNX1T1 to chemotherapeutic agents. Leukemia 20 (10) , pp. 1883-5. 10.1038/sj.leu.2404364

Omidvar, Nader, Pearn, Lorna, Burnett, Alan Kenneth and Darley, Richard Lawrence 2006. Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by Ras. Molecular and cellular biology 26 (10) , pp. 3966-75. 10.1128/MCB.26.10.3966-3975.2006
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Tonks, Alex, Tonks, Amanda Jayne, Pearn, Lorna, Mohamad, Zulkhairi, Burnett, Alan Kenneth and Darley, Richard Lawrence 2005. Optimized retroviral transduction protocol which preserves the primitive subpopulation of human hematopoietic cells. Biotechnology Progress 21 (3) , pp. 953-958. 10.1021/bp0500314

Tonks, Alex, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, Laurence, Hoy, Terence George, Couzens, Stephen, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, L., Hoy, T., Couzens, Stephen, Fisher, J., Burnett, Alan Kenneth and Darley, Richard Lawrence 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence 2003. The AML-1 fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Tonks, Alex, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence 2003. The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Darley, Richard Lawrence, Pearn, Lorna, Omidvar, Nader, Sweeney, Marion Carol, Fisher, Janet, Phillips, Sarah, Hoy, Terence George and Burnett, Alan Kenneth 2002. Protein kinase C mediates mutant N-Ras-induced developmental abnormalities in normal human erythroid cells. Blood 100 (12) , pp. 4185-92. 10.1182/blood-2002-05-1358

Darley, Richard Lawrence, Pearn, Lorna and Burnett, Alan Kenneth 2000. Mutant RAS promotes amplification of primitive human erythroid cells. Blood 96 (11) , 92A-92A.

This list was generated on Fri Dec 13 09:18:25 2019 GMT.