Browse by All Cardiff Authors

Midgley, Adam C., Woods, Emma, Jenkins, Robert, Brown, Charlotte, Khalid, Usman, Chavez, Rafael, Hascall, Vincent, Steadman, Robert, Phillips, Aled O. and Meran, Soma 2020. Hyaluronidase-2 regulates RhoA signalling, myofibroblast contractility and other key pro-fibrotic myofibroblast functions. American Journal of Pathology 190 (6) , pp. 1236-1255. 10.1016/j.ajpath.2020.02.012

Holmes, Jennifer, Donovan, Kieron, Geen, John, Williams, John and Phillips, Aled O. 2020. Acute kidney injury demographics and outcomes: changes following introduction of electronic acute kidney injury alerts—an analysis of a national dataset. Nephrology Dialysis Transplantation , gfaa071. 10.1093/ndt/gfaa071 Item availability restricted.

Foxwell, David A, Pradhan, Sara, Zouwail, Soha, Rainer, Timothy H and Phillips, Aled O 2020. Epidemiology of emergency department acute kidney injury. Nephrology 25 (6) , pp. 457-466. 10.1111/nep.13672 Item availability restricted.

Gubb, Samuel, Holmes, Jennifer, Smith, Graham, Geen, John, Williams, John, Donovan, Kieron and Phillips, Aled O. 2020. Acute kidney injury in children based on electronic alerts. Journal of Pediatrics 220 , 4-6.e1. 10.1016/j.jpeds.2019.11.019 Item availability restricted.

Allen, Lowri A, Pyart, Rhodri D, Holmes, Jennifer, Donovan, Kieron L, Anderson, Richard A and Phillips, Aled O 2019. Cardiovascular and renal outcomes following percutaneous coronary intervention in a population with renal disease: a case-control study. QJM: An International Journal of Medicine 112 (9) , pp. 669-674. 10.1093/qjmed/hcz130

Holmes, Jennifer, Geen, John, Williams, John D and Phillips, Aled O 2019. Recurrent acute kidney injury: predictors and impact in a large population-based cohort. Nephrology Dialysis Transplantation 10.1093/ndt/gfz155 Item availability restricted.

Phillips, Dafydd, Holmes, Jennifer, Davies, Richard, Geen, John, Williams, John D and Phillips, Aled O 2018. The influence of socioeconomic status on presentation and outcome of acute kidney injury. QJM: An International Journal of Medicine 111 (12) , pp. 849-857. 10.1093/qjmed/hcy180

Wang, Junqiao, Nie, Shaoping, Chen, Shuping, Phillips, Aled O., Phillips, Glyn O., Li, Yajing, Xie, Mingyong and Cui, Steve W. 2018. Structural characterization of an α-1, 6-linked galactomannan from natural Cordyceps 2 sinensis. Food Hydrocolloids 78 , pp. 77-91. 10.1016/j.foodhyd.2017.07.024

Huang, Danfei, Meran, Soma, Nie, Shao-Ping, Midgley, Adam C., Wang, Junqiao, Cui, Steve W., Xie, Mingyong, Phillips, Glyn O. and Phillips, Aled O. 2018. Cordyceps Sinensis: anti-fibrotic and inflammatory effects of a cultured polysaccharide extract. Bioactive Carbohydrates and Dietary Fibre 14 , pp. 2-8. 10.1016/j.bcdf.2017.07.012

Midgley, Adam C., Oltean, Sebastian, Hascall, Vincent, Woods, Emma L., Steadman, Robert, Phillips, Aled O. and Meran, Soma 2017. Nuclear hyaluronidase 2 drives alternative splicing of CD44 pre-mRNA to determine profibrotic or antifibrotic cell phenotype. Science Signaling 10 (506) , eaao1822. 10.1126/scisignal.aao1822

Holmes, Jennifer, Geen, John, Phillips, Bethan, Williams, John and Phillips, Aled 2017. Community acquired acute kidney injury: findings from a large population cohort. QJM: An International Journal of Medicine 110 (11) , pp. 741-746. 10.1093/qjmed/hcx151

Phillips, Dafydd, Young, Oliver, Holmes, Jennifer, Allen, Lowri, Roberts, Gethin, Geen, John, Williams, John and Phillips, Aled 2017. Seasonal pattern of incidence and outcome of acute kidney injury: A national study of Welsh AKI electronic alerts. International Journal of Clinical Practice 71 (9) , e13000. 10.1111/ijcp.13000

Holmes, Jennifer, Allen, Nicholas, Roberts, Gethin, Geen, John, Williams, John D. and Phillips, Aled Owain 2017. Acute kidney injury: electronic alerts in primary care - findings from a large population cohort. QJM: An International Journal of Medicine 110 (9) , pp. 577-582. 10.1093/qjmed/hcx080

Holmes, Jennifer, Roberts, Gethin, May, Kate, Tyerman, Kay, Geen, John, Williams, John D. and Phillips, Aled O. 2017. The incidence of pediatric acute kidney injury is increased when identified by a change in a creatinine-based electronic alert. Kidney International 92 (2) , pp. 432-439. 10.1016/j.kint.2017.03.009

Wang, Junqiao, Nie, Shaoping, Cui, Steve W., Wang, Zhijun, Phillips, Aled O., Phillips, Glyn O., Li, Yajing and Xie, Mingyong 2017. Structural characterization and immunostimulatory activity of a glucan from natural Cordyceps sinensis. Food Hydrocolloids 67 , pp. 139-147. 10.1016/j.foodhyd.2017.01.010

Wang, Junqiao, Nie, Shaoping, Kan, Lijiao, Chen, Haihong, Cui, Steve W., Phillips, Aled O., Phillips, Glyn O. and Xie, Mingyong 2017. Comparison of structural features and antioxidant activity of polysaccharides from natural and cultured Cordyceps sinensis. Food Science and Biotechnology 26 (1) , 55. 10.1007/s10068-017-0008-3

Holmes, J, Rainer, Timothy, Geen, J, Roberts, G, May, K, Wilson, N, Williams, JD and Phillips, Aled 2016. Acute kidney injury in the era of the AKI E-Alert. Clinical Journal of the American Society of Nephrology 11 10.2215/CJN.05170516

Johnson, Faye, Phillips, Dafydd, Talabani, Bnar, Wonnacott, Alexa, Meran, Soma and Phillips, Aled 2016. The impact of acute kidney injury in diabetes mellitus. Journal of Thrombosis and Haemostatis 21 (6) , pp. 506-511. 10.1111/nep.12649

Midgley, Adam C., Morris, Glyn, Phillips, Aled O. and Steadman, Robert 2016. 17{beta}-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-{gamma}/STAT1-dependent miR-7 upregulation. Aging Cell 15 (3) , pp. 531-541. 10.1111/acel.12462

Martin, John, Midgley, Adam, Meran, Soma, Woods, Emma, Bowen, Timothy, Phillips, Aled O. and Steadman, Robert 2016. Tumour necrosis factor-stimulated gene (TSG)-6-mediated interactions with the inter-alpha-inhibitor heavy chain 5 facilitate TGF beta1-dependent fibroblast to myofibroblast differentiation. Journal of Biological Chemistry 291 , pp. 13789-13801. 10.1074/jbc.M115.670521

El-hassan, El-hussein E A, Ghalib, Mohamed B, Ibrahim, Azam I S, Phillips, Bethan and Phillips, Aled 2016. Glomerular disease and acute kidney injury in Sudan: Demographics, histological diagnosis and outcome. South African Medical Journal 106 (7) , pp. 704-708. 10.7196/SAMJ.2016.v106i7.10392

Beltrami, Cristina, Clayton, Aled, Newbury, Lucy, Corish, Peter, Jenkins, Robert Hywel, Phillips, Aled Owain, Fraser, Donald James and Bowen, Timothy 2015. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1 (2) , pp. 151-166. 10.3390/ncrna1020151

Roberts, Gareth, Phillips, Dafydd, McCarthy, Rowan, Bolusani, Hemanth, Mizen, Paul, Hassan, Mohamed, Hooper, Rachel, Saddler, Kimberly, Hu, Mo, Lodhi, Sonal, Toynton, Ella, Geen, John, Lodhi, Vikas, Grose, Catherine and Phillips, Aled 2015. Acute kidney injury risk assessment at the hospital front door: what is the best measure of risk? Clinical Kidney Journal 8 (6) , pp. 673-680. 10.1093/ckj/sfv080

Midgley, Adam C., Druggal, Lucy, Jenkins, Robert, Hascall, Vincent, Steadman, Robert, Phillips, Aled O. and Meran, Soma 2015. Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype. Journal of Biological Chemistry 290 (18) , pp. 11218-11234. 10.1074/jbc.M114.625939

Wonnacott, Alexa, Meran, Soma, Amphlett, Bethan, Talabani, Bnar and Phillips, Aled 2014. Epidemiology and outcomes in community-acquired versus hospital-acquired AKI. Clinical Journal of the American Society of Nephrology 9 (6) , pp. 1007-1014. 10.2215/CJN.07920713

Talabani, Bnar, Zouwail, Soha, Pyart, Rhodri, Meran, Soma, Riley, Stephen and Phillips, Aled 2014. Epidemiology and outcome of community-acquired acute kidney injury. Nephrology 19 (5) , pp. 282-287. 10.1111/nep.12221

Jenkins, Robert H., Davies, Luke C., Taylor, Philip R., Akiyama, Hideo, Cumbes, Bevan, Beltrami, Cristina, Carrington, Christopher P., Phillips, Aled O., Bowen, Timothy and Fraser, Donald J. 2014. miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. American Journal of Pathology 184 (4) , pp. 996-1009. 10.1016/j.ajpath.2013.12.028

Midgley, Adam C., Bowen, Timothy, Phillips, Aled O. and Steadman, Robert 2014. MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell 13 (2) , pp. 235-244. 10.1111/acel.12167

Yao, Xiaolin, Meran, Soma, Fang, Yapeng, Martin, John, Midgley, Adam, Pan, Ming-Ming, Liu, Bi-Cheng, Cui, Steve W., Phillips, Glyn O. and Phillips, Aled 2014. Cordyceps sinensis: in vitro anti-fibrotic bioactivity of natural and cultured preparations. Food Hydrocolloids 35 , pp. 444-452. 10.1016/j.foodhyd.2013.06.023

Meran, Soma, Wonnacott, Alexa, Amphlett, Bethan and Phillips, Aled 2014. How good are we at managing acute kidney injury in hospital? Clinical Kidney Journal 7 (2) , pp. 144-150. 10.1093/ckj/sfu010

Phillips, B M., Milner, S, Zouwail, S, Roberts, G, Cowan, M, Riley, Stephen and Phillips, Aled 2014. Severe hyperkalaemia: demographics and outcome. Clinical Kidney Journal 7 (2) , pp. 127-133. 10.1093/ckj/sft158

Phillips, L.A., Phillips, Bethan, Meran, Soma, Russell, J., Zouwail, S., Riley, Stephen and Phillips, Aled 2014. The long-term impact of eGFR reporting on referral patterns. European Journal of Internal Medicine 25 (1) , pp. 97-101. 10.1016/j.ejim.2013.08.001

Jones, Nia J., Chess, James Anthony, Cawley, Scott, Phillips, Aled Owain and Riley, Stephen George 2013. Prevalence of risk factors for foot ulceration in a general haemodialysis population. International Wound Journal 10 (6) , pp. 683-688. 10.1111/j.1742-481X.2012.01044.x

Jones, Ruth K., Hampton, D., O'Sullivan, D. J. and Phillips, Aled Owain 2013. Diabetes and renal disease: who does what? Clinical Medicine 13 (5) , pp. 460-464. 10.7861/clinmedicine.13-5-460

Pan, M., Zhang, M., Ni, H., Chen, J., Xu, M., Phillips, Aled Owen and Liu, B. 2013. Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats. Food and Chemical Toxicology 58 , pp. 487-494. 10.1016/j.fct.2013.04.037

Meran, Soma, Martin, John, Luo, Dong Dong, Steadman, Robert and Phillips, Aled Owain 2013. Interleukin-1β induces hyaluronan and CD44-dependent cell protrusions that facilitate fibroblast-monocyte binding. American Journal of Pathology 182 (6) , pp. 2223-2240. 10.1016/j.ajpath.2013.02.038

Midgley, Adam Christopher, Rogers, Mathew James, Hallett, Maurice Bartlett, Clayton, Aled, Bowen, Timothy, Phillips, Aled Owain and Steadman, Robert 2013. Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation Is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. Journal of Biological Chemistry 288 (21) , pp. 14824-14838. 10.1074/jbc.M113.451336

Phillips, Lowri Angharad, Allen, Nicholas, Phillips, Bethan, Abera, Ammanuel, Diro, Ermias, Riley, Stephen George, Tadesse, Yewondwossen, Williams, John David and Phillips, Aled Owain 2013. Acute kidney injury risk factor recognition in three teaching hospitals in Ethiopia. South African Medical Journal 103 (6) , pp. 413-418. 10.7196/samj.6424

Nie, Shaoping, Cui, Steve W., Xie, Mingyong, Phillips, Aled Owain and Phillips, Glyn O. 2013. Bioactive polysaccharides from Cordyceps sinensis: Isolation, structure features and bioactivities [Review]. Bioactive Carbohydrates and Dietary Fibre 1 (1) , pp. 38-52. 10.1016/j.bcdf.2012.12.002

Riley, Stephen George, Diro, E., Batchelor, P., Abebe, A., Amsalu, A., Tadesse, T., Williams, John David and Phillips, Aled Owain 2013. Renal impairment amongst acute hospital admissions in a rural Ethiopian hospital. Nephrology 18 (2) , pp. 92-96. 10.1111/nep.12002

Wonnacott, Alexa, Meran, Soma, Roberts, Gareth Wyn, Donovan, Kieron, Riley, Stephen George and Phillips, Aled Owain 2012. Applying estimated glomerular filtration rate to an ageing population: are we in danger of becoming ageist? European Journal of Internal Medicine 23 (8) , pp. 705-710. 10.1016/j.ejim.2012.08.012

Zhang, Xiao Liang, Bi-Cheng, Liu, Al-Assaf, Saphwan, Phillips, Glyn O. and Phillips, Aled Owain 2012. Cordyceps sinensis decreases TGF-β1 dependent epithelial to mesenchymal transdifferentiation and attenuates renal fibrosis. Food Hydrocolloids 28 (1) , pp. 200-212. 10.1016/j.foodhyd.2011.12.016

Jenkins, Robert Hywel, Martin, John, Phillips, Aled Owain, Bowen, Timothy and Fraser, Donald James 2012. Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding. Biochemical Journal 443 (2) , pp. 407-416. 10.1042/BJ20111861

Zheng, Min, Lv, Lin-Li, Cao, Yu-Han, Zhang, Jian-Dong, Wu, Min, Ma, Kun-Ling, Phillips, Aled Owain and Liu, Bi-Cheng 2012. Urinary mRNA markers of epithelial-mesenchymal transition correlate with progression of diabetic nephropathy. Clinical Endocrinology 76 (5) , pp. 657-664. 10.1111/j.1365-2265.2011.04192.x

Jenkins, Robert Hywel, Martin, John, Phillips, Aled Owain, Bowen, Timothy and Fraser, Donald James 2012. Pleiotropy of microRNA-192 in the kidney. Biochemical Society Transactions 40 (4) , pp. 762-767. 10.1042/BST20120085

Beltrami, Cristina, Clayton, Aled, Phillips, Aled Owain, Fraser, Donald James and Bowen, Timothy 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40 (4) , pp. 875-879. 10.1042/BST20120090

Beltrami, Cristina, Clayton, Aled, Phillips, Aled Owain, Fraser, Donald James and Bowen, Timothy 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40 (4) , pp. 875-879. 10.1042/BST20120090

Bommayya, Girish, Meran, Soma, Krupa, Aleksandra, Phillips, Aled Owain and Steadman, Robert 2011. Tumour necrosis factor-stimulated gene (TSG)-6 controls epithelial–mesenchymal transition of proximal tubular epithelial cells. International Journal of Biochemistry & Cell Biology 43 (12) , pp. 1739-1746. 10.1016/j.biocel.2011.08.009

Michael, Daryn Robert, Phillips, Aled Owain, Krupa, Aleksandra, Martin, John, Redman, James Edward, Altaher, Abdalsamed, Neville, Rachel Dawn, Webber, Jason P., Kim, Min-Young and Bowen, Timothy 2011. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. Journal of Biological Chemistry 286 (22) , pp. 19523-19532. 10.1074/jbc.M111.233916

Li, Qing, Liu, Bi-Cheng, Lv, Lin-Li, Ma, Kun-Ling, Zhang, Xiao-Liang and Phillips, Aled Owain 2011. Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1. Journal of Cellular Biochemistry 112 (6) , pp. 1585-1592. 10.1002/jcb.23074

Meran, Soma, Luo, Dong Dong, Simpson, Russell M. L., Martin, John, Wells, Alan, Steadman, Robert and Phillips, Aled Owain 2011. Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction. Journal of Biological Chemistry 286 (20) , pp. 17618-17630. 10.1074/jbc.M111.226563

Martin, John, Jenkins, Robert Hywel, Bennagi, Rasha, Krupa, Aleksandra, Phillips, Aled Owain, Bowen, Timothy and Fraser, Donald James 2011. Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744. PLoS ONE 6 (10) , e25044. 10.1371/journal.pone.0025044

Asderakis, Argiris, Chaudhry, Aisha, Ilham, Mohamed Adel, Stephens, Michael and Phillips, Aled Owain 2011. RO-101 Nitric oxide post-perfusion levels differ in DCD and DBD donor transplants [Abstract]. Transplant International 24 (s2) , p. 157. 10.1111/j.1432-2277.2011.01350.x

Nie, Shao-Ping, Cui, Steve W., Phillips, Aled Owain, Xie, Ming-Yong, Phillips, Glyn O., Al-Assaf, Saphwan and Zhang, Xiao-Liang 2011. Elucidation of the structure of a bioactive hydrophilic polysaccharide from Cordyceps sinensis by methylation analysis and NMR spectroscopy. Carbohydrate Polymers 84 (3) , pp. 894-899. 10.1016/j.carbpol.2010.12.033

Phillips, Aled Owain and Phillips, Glyn O. 2011. Biofunctional behaviour and health benefits of a specific gum arabic. Food Hydrocolloids 25 (2) , pp. 165-169. 10.1016/j.foodhyd.2010.03.012

Tian, Ya-Chung, Hung, Cheng-Chieh, Li, Yi-Jung, Chen, Yung-Chang, Chang, Ming-Yang, Yen, Tzung-Hai, Hsu, Hsiang-Hao, Wu, Mai-Szu, Phillips, Aled Owain and Yang, Chih-Wei 2011. Leptospira santorosai serovar shermani detergent extract induces an increase in fibronectin production through a toll-like receptor 2-mediated pathway. Infection and Immunity 79 (3) , pp. 1134-1142. 10.1128/IAI.01287-09

Khammas, Hassan, Bowen, Timothy, Williams, John David, Phillips, Aled Owain, Steadman, Robert and Martin, John 2011. Characterisation of the human ADAM15 promoter. Nephron Experimental Nephrology 118 (2) , e27-e38. 10.1159/000320698

Jenkins, Robert Hywel, Bennagi, Rasha, Martin, John, Phillips, Aled Owain, Redman, James Edward and Fraser, Donald James 2010. A conserved stem loop motif in the 5'Untranslated Region regulates transforming growth factor-β1 translation. PLoS One 5 (8) , e12283. 10.1371/journal.pone.0012283

Simpson, Russell M. L., Wells, Alan, Thomas, David William, Stephens, Philip, Steadman, Robert and Phillips, Aled Owain 2010. Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling. American Journal of Pathology 176 (3) , pp. 1215-1228. 10.2353/ajpath.2010.090802

Krupa, Aleksandra, Jenkins, Robert Hywel, Luo, Dong Dong, Lewis, Aled G., Phillips, Aled Owain and Fraser, Donald James 2010. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. Journal of the American Society of Nephrology 21 (3) , pp. 438-447. 10.1681/ASN.2009050530

Meran, Soma, Don, K, Shah, Nilesh, Donovan, Kieron, Riley, Stephen George and Phillips, Aled Owain 2010. Impact of chronic kidney disease management in primary care. QJM 104 (1) , pp. 27-34. 10.1093/qjmed/hcq151

Phillips, Aled Owain and Fraser, Donald James 2010. BMP-7 stops TGF-β in peritoneal fibrosis. Nephrology Dialysis Transplantation 25 (4) , pp. 1036-1038. 10.1093/ndt/gfq032

Luo, Dong Dong, Phillips, Aled Owain and Fraser, Donald James 2010. Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell smad3 signaling via increased SnoN expression. American Journal of Pathology 176 (3) , pp. 1139-1147. 10.2353/ajpath.2010.090459

Simpson, Russell M. L., Meran, Soma, Thomas, David William, Stephens, Philip, Bowen, Timothy, Steadman, Robert and Phillips, Aled Owain 2009. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. American Journal of Pathology 175 (5) , pp. 1915-1928. 10.2353/ajpath.2009.090045

Webber, Jason P., Jenkins, Robert Hywel, Meran, Soma, Phillips, Aled Owain and Steadman, Robert 2009. Modulation of TGFβ1-dependent myofibroblast differentiation by hyaluronan. American Journal of Pathology 175 (1) , pp. 148-160. 10.2353/ajpath.2009.080837

Webber, Jason P., Meran, Soma, Steadman, Robert and Phillips, Aled Owain 2009. Hyaluronan orchestrates transforming growth factor-β1-dependent maintenance of myofibroblast phenotype. Journal of Biological Chemistry 284 (14) , pp. 9083-9092. 10.1074/jbc.M806989200

Simpson, Russell M.L., Stephens, Philip, Thomas, David, Webber, J. P., Meran, Soma, Steadman, Robert and Phillips, Aled Owain 2009. Age related changes in pericellular hyaluronan leads to impaired dermal fibroblast to myofibroblast differentiation. International Journal of Experimental Pathology 90 (2) , A128-A129.

Luo, Dong Dong, Fielding, Ceri Alan, Phillips, Aled Owain and Fraser, Donald James 2009. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrology Dialysis Transplantation 24 (9) , pp. 2655-2665. 10.1093/ndt/gfp208

Glover, David A., Ushida, Kazunari, Phillips, Aled Owain and Riley, Stephen George 2009. Acacia(sen) SUPERGUM™ (gum arabic): an evaluation of potential health benefits in human subjects. Food Hydrocolloids 23 (8) , pp. 2410-2415. 10.1016/j.foodhyd.2009.06.020

Phillips, L. A., Donovan, Kieron and Phillips, Aled Owain 2009. Renal quality outcomes framework and eGFR: impact on secondary care. QJM 102 (6) , pp. 415-423. 10.1093/qjmed/hcp030

Meran, Soma, Thomas, David William, Stephens, Philip, Enoch, Stuart, Martin, John, Steadman, Robert and Phillips, Aled Owain 2008. Hyaluronan facilitates transforming growth factor-β1-mediated fibroblast proliferation. Journal of Biological Chemistry 283 (10) , pp. 6530-6545. 10.1074/jbc.M704819200

Fraser, Donald James, Phillips, Aled Owen, Zhang, Xiao Liang, van Roeyen, C. R., Muehlenberg, P., En-Nia, A. and Mertens, P. R. 2008. Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells. Kidney International 73 (6) , pp. 724-732. 10.1038/sj.ki.5002719

Lewis, Aled G., Steadman, Robert, Manley, Paul, Craig, Kathrine Jane, de la Motte, Carol, Hascall, Vincent and Phillips, Aled Owain 2008. Diabetic nephropathy, inflammation, hyaluronan and interstitial fibrosis. Histology and Histopathology 23 (6) , pp. 731-739.

Chang, Chiz-Tzung, Hung, Cheng-Chieh, Chen, Yung-Chang, Yen, Tzung-Hai, Wu, Mai-Szu, Yang, Chih-Wei, Phillips, Aled Owain and Tian, Ya-Chung 2008. Transforming growth factor-β1 decreases epithelial sodium channel functionality in renal collecting duct cells via a Smad4-dependent pathway. Nephrology Dialysis Transplantation 23 (4) , pp. 1126-1134. 10.1093/ndt/gfm786

Liu, B. C., Li, M. X., Zhang, J. D., Liu, X. C., Zhang, X. L. and Phillips, Aled Owain 2008. Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition. American Journal of Nephrology 28 (1) , pp. 143-151. 10.1159/000110019

Nair, S., Phillips, Aled Owain, Norton, Nadine, Spurlock, Gillian, Williams, Hywel John, Craig, Kathrine Jane, Williams, John David, Williams, Nigel Melville and Bowen, Timothy 2008. Further evidence for the association of MMP9 with nephropathy in type 2 diabetes and application of DNA pooling technology to candidate gene screening. Journal of Nephology 21 (3) , pp. 400-405.

Meran, Soma, Steadman, Robert, Phillips, Aled Owain, Thomas, David William and Stephens, Philip 2008. Hyaluronan facilitates TGF beta 1 mediated myofibroblastic differentiation [Abstract]. Wound Repair and Regeneration 16 (2) , A12. 10.1111/j.1524-475X.2008.00371.x

Zhang, M., Lee, C., Luo, D. D., Krupa, A., Fraser, Donald James and Phillips, Aled Owain 2007. Polarity of response to transforming growth factor-beta1 in proximal tubular epithelial cells is regulated by beta-catenin. Journal of Biological Chemistry 282 (39) , pp. 28639-28647. 10.1074/jbc.m700594200

Meran, Soma, Thomas, David William, Stephens, Philip, Martin, John, Bowen, Timothy, Phillips, Aled Owain and Steadman, Robert 2007. Involvement of hyaluronan in regulation of fibroblast phenotype. The Journal of Biological Chemistry 282 (35) , pp. 25687-25697. 10.1074/jbc.M700773200

Zhang, M., Fraser, Donald James and Phillips, Aled Owain 2006. ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. American Journal of Pathology 169 (4) , pp. 1282-1293. 10.2353/ajpath.2006.050921

Rashid Selbi, Wisam, de la Motte, C. A., Hascall, V. C., Day, A. J., Bowen, Timothy and Phillips, Aled Owain 2006. Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells. Kidney International 70 (7) , pp. 1287-1295. 10.1038/sj.ki.5001760

Khera, Tarnjit, Martin, John, Riley, Stephen George, Steadman, Robert and Phillips, Aled Owain 2006. Glucose enhances mesangial cell apoptosis. Laboratory Investigation 86 (6) , pp. 566-577. 10.1038/labinvest.3700418

Matsumoto, N., Riley, Stephen George, Fraser, Donald James, Al-Assaf, S., Ishimura, E., Wolever, T., Phillips, G. O. and Phillips, Aled Owain 2006. Butyrate modulates TGF-beta1 generation and function: potential renal benefit for Acacia(sen) SUPERGUM (gum arabic)? Kidney International 69 (2) , pp. 257-65. 10.1038/sj.ki.5000028

Craig, Kathrine Jane, Williams, John David, Riley, Stephen George, Smith, Hilary, Owens, David Raymond, Worthing, Debbie, Cavill, Ivor and Phillips, Aled Owain 2005. Anemia and diabetes in the absence of nephropathy. Diabetes Care 28 (5) , pp. 1118-1123. 10.2337/diacare.28.5.1118

Zhang, Xiao Liang, Topley, Nicholas, Ito, Takafumi and Phillips, Aled Owain 2005. Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling. The Journal of Biological Chemistry 280 (13) , pp. 12239-12245. 10.1074/jbc.M413284200

Zhang, Xiao Liang, Rashid Selbi, Wisam Dhafir, Motte, Carol de la, Hascall, Vincent and Phillips, Aled Owain 2005. Bone morphogenic protein-7 inhibits monocyte-stimulated TGF-beta1 generation in renal proximal tubular epithelial cells. Journal of the American Society of Nephrology 16 (1) , pp. 79-89. 10.1681/ASN.2004050395

Craig, K. L., Riley, Stephen George, Thomas, B., Penney, M., Donovan, Kieron and Phillips, Aled Owain 2005. The impact of an out-reach clinic on referral of patients with renal impairment. Nephron Clinical Practice 101 (4) , c168-c173. 10.1159/000087392

Zhang, Xiao Liang, Rashid Selbi, Wisam Dhafir, Motte, Carol de la, Hascall, Vincent and Phillips, Aled Owain 2004. Renal proximal tubular epithelial cell transforming growth factor-beta1 generation and monocyte binding. American Journal of Pathology 165 (3) , pp. 763-773.

Ito, Takafumi, Williams, John David, Fraser, Donald James and Phillips, Aled Owain 2004. Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization. The Journal of Biological Chemistry 279 (24) , pp. 25326-25332. 10.1074/jbc.M403135200

Ito, T., Williams, J. D., Fraser, Donald and Phillips, Aled Owen 2004. Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. American Journal of Pathology 164 (6) , pp. 1979-1988. 10.1016/s0002-9440(10)63758-3

Fraser, Donald James, Brunskill, Nigel, Ito, Takafumi and Phillips, Aled Owain 2003. Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop. American Journal of Pathology 163 (6) , pp. 2565-2574.

Tian, Ya-Chung, Fraser, Donald James, Attisano, Liliana and Phillips, Aled Owain 2003. TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype. American Journal of Physiology - Renal Physiology 285 (1) , F130-142. 10.1152/ajprenal.00408.2002

Craig, Kathrine Jane, Donovan, Kieron, Munnery, Margaret, Owens, David Raymond, Williams, John David and Phillips, Aled Owain 2003. Identification and management of diabetic nephropathy in the diabetes clinic. Diabetes Care 26 (6) , pp. 1806-1811. 10.2337/diacare.26.6.1806

Wong, Teresa Y. H., Phillips, Aled Owain, Witowski, Janusz and Topley, Nicholas 2003. Glucose-mediated induction of TGF-beta 1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent. Kidney International 63 (4) , pp. 1404-1416. 10.1046/j.1523-1755.2003.00883.x

Fraser, Donald James, Phillips, Aled Owain and Wakefield, Lalage 2002. Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. American Journal of Pathology 161 (3) , pp. 1039-1049.