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Number of items: 13.

Ordonez, Liliana D, Hay, Trevor, McEwen, Robert, Polanska, Urszula M, Hughes, Adina, Delpuech, Oona, Cadogan, Elaine, Powell, Steve, Dry, Jonathan, Tornillo, Giusy, Silcock, Lucy, Leo, Elisabetta, O'Connor, Mark J, Clarke, Alan R and Smalley, Matthew J. 2019. Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours. Oncotarget 10 (27) , pp. 2586-2606. 10.18632/oncotarget.26830
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Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R., Smalley, Matthew J. and Clarke, Alan R. 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19 , 677. 10.1186/s12885-019-5867-y
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Bird, Thomas G., Müller, Miryam, Boulter, Luke, Vincent, David F., Ridgway, Rachel A., Lopez-Guadamillas, Elena, Lu, Wei-Yu, Jamieson, Thomas, Govaere, Olivier, Campbell, Andrew D., Ferreira-Gonzalez, Sofía, Cole, Alicia M., Hay, Trevor, Simpson, Kenneth J., Clark, William, Hedley, Ann, Clarke, Mairi, Gentaz, Pauline, Nixon, Colin, Bryce, Steven, Kiourtis, Christos, Sprangers, Joep, Nibbs, Robert J. B., Van Rooijen, Nico, Bartholin, Laurent, McGreal, Steven R., Apte, Udayan, Barry, Simon T., Iredale, John P., Clarke, Alan R., Serrano, Manuel, Roskams, Tania A., Sansom, Owen J. and Forbes, Stuart J. 2018. TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Science Translational Medicine 10 (454) , eaan1230. 10.1126/scitranslmed.aan1230

Johnson, Charlotte E., Dunlop, Elaine A., Seifan, Sara, McCann, Henry D., Hay, Trevor, Parfitt, Geraint J., Jones, Ashley T., Giles, Peter J., Shen, Ming H., Sampson, Julian R., Errington, Rachel J., Davies, David Mark and Tee, Andrew R. 2018. Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir−bortezomib therapy to intensify endoplasmic reticulum stress-induced cell death. Oncogene 37 , pp. 5913-5925. 10.1038/s41388-018-0381-2
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Lu, Wei-Yu, Bird, Thomas G., Boulter, Luke, Tsuchiya, Atsunori, Cole, Alicia M., Hay, Trevor, Guest, Rachel V., Wojtacha, Davina, Man, Tak Yung, Mackinnon, Alison, Ridgway, Rachel A., Kendall, Timothy, Williams, Michael J., Jamieson, Thomas, Raven, Alex, Hay, David C., Iredale, John P., Clarke, Alan Richard, Sansom, Owen J. and Forbes, Stuart J. 2015. Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nature Cell Biology 17 (8) , pp. 971-983. 10.1038/ncb3203

Tangudu, N. K., Verma, V. K., Clemons, T. D., Beevi, S. S., Hay, Trevor, Mahidhara, G., Raja, Meera, Nair, R. A., Alexander, L. E., Patel, A. B., Jose, J., Smith, N. M., Zdyrko, B., Bourdoncle, A., Luzinov, I., Iyer, K. S., Clarke, Alan Richard and Dinesh Kumar, L. 2015. RNA interference using c-Myc-conjugated nanoparticles suppresses breast and colorectal cancer models. Molecular Cancer Therapeutics 14 (5) , pp. 1259-1269. 10.1158/1535-7163.MCT-14-0970

Bird, T., Cole, A., Hay, Trevor James, Iredale, J. P., Clarke, Alan Richard, Sansom, O. J. and Forbes, S. J. 2009. A novel inducible genetic murine model of hepatocyte senescence causes a massive hepatic oval cell response and complete hepatocyte replacement from endogenous progenitor cells [Abstract]. Journal of Hepatology 50 (S1) , S3.

Hay, Trevor James, Matthews, J. R., Pietzka, Lucie Charlotte, Lau, A., Cranston, A., Nygren, A. O. H., Douglas-Jones, A., Smith, G. C. M., Martin, N. M. B., O'Connor, M. and Clarke, Alan Richard 2009. Poly(ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin. Cancer Research 69 (9) , pp. 3850-3855. 10.1158/0008-5472.CAN-08-2388

Meniel, Valerie, Hay, Trevor, Douglas-Jones, Anthony Gordon, Sansom, Owen J. and Clarke, Alan R. 2005. Mutations in Apc and p53 synergize to promote mammary neoplasia. Cancer Research 65 (24) , pp. 410-6.

Hay, Trevor, Jenkins, Helen, Sansom, Owen J, Martin, Niall M. B., Smith, Graeme C. M. and Clarke, Alan Richard 2005. Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy. Cancer Research 65 (22) , p. 10145. 10.1158/0008-5472.CAN-05-1186

Clarke, Alan Richard and Hay, Trevor 2005. DNA damage hypersensitivity in cells lacking BRCA2: a review of in vitro and in vivo data. Biochemical Society Transactions 33 (4) , pp. 715-717. 10.1042/BST0330715

Hay, Trevor, Patrick, Teresa, Winton, Douglas, Sansom, Owen J. and Clarke, Alan Richard 2005. Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells. Oncogene 24 (23) , pp. 3842-3846. 10.1038/sj.onc.1208533

Gallagher, Ronald C. J., Hay, Trevor, Meniel, Valerie, Naughton, Catherine, Anderson, Thomas J., Shibata, Hiroyuki, Ito, Masaki, Clevers, Hans, Noda, Tetsuo, Sansom, Owen J., Mason, John O. and Clarke, Alan Richard 2002. Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. Oncogene 21 (42) , pp. 6446-6457. 10.1038/sj.onc.1205892

This list was generated on Sun Dec 15 08:40:41 2019 GMT.