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Number of items: 14.

Young, Madeleine A., May, Stephanie, Damo, Angelos, Yoon, Young So, Hur, Man-Wook, Swat, Wojiech and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2019. Epigenetic regulation of Dlg1, via Kaiso, alters mitotic spindle polarity and promotes intestinal tumourigenesis. Molecular Cancer Research 17 (3) , pp. 686-696. 10.1158/1541-7786.MCR-18-0280
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Young, Madeleine, Daly, Carl, Taylor, Elaine, James, Rhiannon, Clarke, Alan and Reed, Karen ORCID: https://orcid.org/0000-0002-7467-1718 2018. Subtle deregulation of the Wnt-signalling pathway through loss of Apc2 reduces the fitness of intestinal stem cells. Stem Cells 36 (1) , pp. 114-122. 10.1002/stem.2712
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Young, Madeleine and Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718 2016. Organoids as a model for colorectal cancer. Current Colorectal Cancer Reports 12 (5) , pp. 281-287. 10.1007/s11888-016-0335-4
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Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Song, Fei, Young, Madeleine, Hassan, N., Antoine, A. J., Gemici, Nesibe-Princess B, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Jenkins, J. R. 2016. Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. Oncotarget 7 (32) , pp. 51665-51673. 10.18632/oncotarget.10076
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Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Protocols for analyzing the role of Paneth cells in regenerating the murine intestine using conditional cre-lox mouse models. Journal of Visualized Experiments (105) , e53429. 10.3791/53429
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Meniel, Valerie, Megges, M., Young, Madeleine, Cole, A., Sansom, O. J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Apc and p53 interaction in DNA damage and genomic instability in hepatocytes. Oncogene 34 , pp. 4118-4129. 10.1038/onc.2014.342

Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Metzger, Daniel, Shorning, Boris Y. and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453
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Holik, Aliaksei, Krzystyniak, Joanna, Young, Madeleine, Richardson, Kirsty, Jarde, Thierry, Chambon, Pierre, Shorning, Boris and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner. Stem Cells 31 (11) , pp. 2457-2466. 10.1002/stem.1498

Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Evidence for a crucial role of Paneth Cells in mediating the intestinal response to injury. Stem Cells 31 (4) , pp. 776-785. 10.1002/stem.1326
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Young, Madeleine, Ordonez, Liliana and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. What are the best routes to effectively model human colorectal cancer? Molecular Oncology 7 (2) , pp. 178-189. 10.1016/j.molonc.2013.02.006

Meniel, Valerie, Song, Fei, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Young, Madeleine, Poetz, Oliver, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Jenkins, John R., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Dunwoodie, Sally L., Watson, Alastair and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Cited1 deficiency suppresses intestinal tumorigenesis. PLoS Genetics 9 (8) , e1003638. 10.1371/journal.pgen.1003638
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Young, Madeleine 2013. The effects of aberrant Wnt signalling on the murine intestinal stem cell compartment. PhD Thesis, Cardiff University.
Item availability restricted.
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Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Tunster, Simon James ORCID: https://orcid.org/0000-0002-2242-9452, Young, Madeleine, Carrico, Adam Stephen, John, Rosalind Margaret ORCID: https://orcid.org/0000-0002-3827-7617 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice. Gut 61 (10) , pp. 1435-1438. 10.1136/gutjnl-2011-300842

Young, Madeleine and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. Expanding the p53 toolkit: A new platform for rapid engineering of the p53 locus in vivo [Note]. Cell Cycle 10 (14) , p. 2249. 10.4161/cc.10.14.16205

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