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Number of items: 38.

Davis, Terence, Rokicki, Michal Jaroslaw, Bagley, Mark C. and Kipling, David Glyn 2013. The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome. Chemistry Central Journal 7 , 18. 10.1186/1752-153X-7-18
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Tivey, Hannah S. E., Rokicki, Michal Jaroslaw, Barnacle, James R., Rogers, Mathew James, Bagley, Mark C., Kipling, David Glyn and Davis, Terence 2013. Small molecule inhibition of p38 MAP kinase extends the replicative life span of human ATR-Seckel syndrome fibroblasts. The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 68 (9) , pp. 1001-1009. 10.1093/gerona/gls336
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Weekes, Ashley Ann, Bagley, Mark Christopher and Westwell, Andrew D. 2011. An efficient synthetic route to biologically relevant 2-phenylbenzothiazoles substituted on the benzothiazole ring. Tetrahedron 67 (40) , pp. 7743-7747. 10.1016/j.tet.2011.08.004

United States of America as represented by the Secretary of the Department of Health and Human Services; Centers for Disease Control and Prevention; Creare Inc. 2011. Aerosol delivery systems and methods. Patent US 07954486. [Patent].

Davis, Terence, Dix, Matthew Charles, Rokicki, Michal Jaroslaw, Brook, Amy Jayne Chedzoy, Widdowson, Caroline Susan, Kipling, David Glyn and Bagley, Mark Christopher 2011. Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors. Chemistry Central Journal 5 (1) , pp. 83-88. 10.1186/1752-153X-5-83

Pradal, J., Jordan, O., Gabay, C., Guerne, P. A., Bagley, Mark Christopher, Doelker, E., Allemann, E. and Waldburger, J. M. 2011. In vitro activity of P38 MAPK inhibitor-loaded particles for the long term intra-articular treatment of osteoarthritis [Abstract]. Annals of the Rheumatic Diseases 70 (S2) , A78-A79. 10.1136/ard.2010.149013.26

Arshad, Afsheen, Osman, Hasnah, Bagley, Mark Christopher, Lam, Chan Kit, Mohamad, Suriyati and Zahariluddin, Anis Safirah Mohd 2011. Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives. European Journal of Medicinal Chemistry 46 (9) , pp. 3788-3794. 10.1016/j.ejmech.2011.05.044

Gaber, H. M. and Bagley, Mark Christopher 2011. Regioselective synthesis and biological evaluation of some novel thiophene-containing heterocyclic scaffolds as potential chemotherapeutic agents. European Journal of Chemistry 2 (2) , pp. 214-222. 10.5155/eurjchem.2.2.214-222.411

Gaber, H. M., Bagley, Mark Christopher, Sherif, S. M. and Sayed, M. A. 2011. Novel phenylazo derivatives of condensed and uncondensed thiophene: synthesis, characterization, and antimicrobial studies. Zeitschrift fur Naturforschung B - A Journal of Chemical Sciences 66 (6) , pp. 585-596. 10.1002/chin.201143098

Bagley, Mark Christopher 2011. Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome (vol 2, pg 193, 2010) [Corrigendum]. Future Medicinal Chemistry 3 (1) , p. 138.

Bagley, Mark Christopher, Davis, Terence, Latimer, Joanna Elizabeth and Kipling, David Glyn 2011. The contribution of biogerontology to quality ageing. Quality in Ageing and Older Adults 12 (1) , pp. 26-32. 10.5042/qiaoa.2011.0142

Latimer, Joanna Elizabeth, Davis, Terence, Bagley, Mark Christopher and Kipling, David Glyn 2011. Ageing science, health care and social inclusion of older people. Quality in Ageing and Older Adults 12 (1) , pp. 11-16. 10.5042/qiaoa.2011.0140

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew, Fusillo, Vincenzo, Pigeaux, Morgane, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2010. Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome. Future Medicinal Chemistry 2 (9) , pp. 1417-1427. 10.4155/fmc.10.217

Bagley, Mark C., Davis, Terence, Murziani, Paola G. S., Widdowson, Caroline and Kipling, David Glyn 2010. Use of p38 MAPK inhibitors for the treatment of Werner Syndrome. Pharmaceuticals 3 (6) , pp. 1842-1872. 10.3390/ph3061842
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Bagley, Mark Christopher, Fusillo, Vincenzo, Jenkins, Robert Leyshon, Lubinu, M. Caterina and Mason, Christopher 2010. Continuous flow processing from microreactors to mesoscale: the Bohlmann-Rahtz cyclodehydration reaction. Organic and Biomolecular Chemistry 8 (9) , pp. 2245-2251. 10.1039/b926387j

Bagley, Mark Christopher, Lin, Zhifan and Pope, Simon J. A. 2010. Microwave-assisted synthesis and complexation of luminescent cyanobipyridyl-zinc(ii) bis(thiolate) complexes with intrinsic and ancillary photophysical tunability. Dalton Transactions 39 (13) , pp. 3163-3166. 10.1039/c001898h

Weekes, Ashley Ann, Dix, Matthew C., Bagley, Mark Christopher and Westwell, Andrew D. 2010. Rapid and convenient thermal or microwave-assisted synthesis of substituted 2-Phenylbenzothiazoles. Synthetic Communications 40 (20) , pp. 3027-3032. 10.1080/00397910903353739

Bagley, Mark Christopher and Glover, Christian C. F. 2010. Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide. Molecules 15 (5) , pp. 3211-3227. 10.3390/molecules15053211
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Gaber, Hatem M., Bagley, Mark Christopher, Sherif, Sherif M. and Abdul-Raouf, Usama M. 2010. Promising antimicrobial agents: Synthetic approaches to novel tricyclic and tetracyclic pyrimidinones with antimicrobial properties. Journal of Heterocyclic chemistry 47 (5) , pp. 1162-1170. 10.1002/jhet.446

Davis, Terence, Bachler, Marcus Aurelius, Wyllie, Fiona Sandra, Bagley, Mark Christopher and Kipling, David 2010. Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts. Annals of the New York Academy of Sciences 1197 (1) , pp. 45-48. 10.1111/j.1749-6632.2010.05195.x

Bagley, Mark Christopher, Davis, Terence, Rokicki, Michal Jaroslaw, Widdowson, Caroline Susan and Kipling, David Glyn 2010. Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome. Future Medicinal Chemistry 2 (2) , pp. 193-201. 10.4155/fmc.09.163

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2010. Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells. Future Medicinal Chemistry 2 (2) , pp. 203-213. 10.4155/fmc.09.160

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Fusillo, Vincenzo, Pigeaux, Morgane, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2009. Microwave-assisted Ullmann C-S bond formation: synthesis of the P38 alpha MAPK clinical candidate VX-745. Journal of Organic Chemistry 74 (21) , pp. 8336-8342. 10.1021/jo9017155

Bagley, Mark Christopher, Dix, M. C. and Fusillo, V. 2009. Rapid Ullmann-type synthesis of aryl sulfides using a copper(I) catalyst and ligand under microwave irradiation. Tetrahedron Letters 50 (26) , pp. 3661-3664. 10.1016/j.tetlet.2009.03.115

Bagley, Mark Christopher, Lin, Z. F. and Pope, Simon J. A. 2009. Rapid synthesis of 3-cyanopyridine-derived chromophores with two-dimensional tunability and solvatochromic photophysical properties. Chemical Communications (34) , pp. 5165-5167. 10.1039/b910664b

Gaber, H. M. and Bagley, Mark Christopher 2009. Unlocking the Chemotherapeutic Potential of beta-Aminovinyl Ketones and Related Compounds. Chemmedchem 4 (7) , pp. 1043-1050. 10.1002/cmdc.200900006

Bagley, Mark Christopher, Lin, Zhifan, Phillips, David J. and Graham, Andy 2009. Barium manganate in microwave-assisted oxidation reactions: synthesis of lactones by oxidative cyclization of diols. Tetrahedron Letters 50 (49) , pp. 6823-6825. 10.1016/j.tetlet.2009.09.117

Bagley, Mark Christopher, Lin, Zhifan and Pope, Simon J. A. 2009. Barium manganate in microwave-assisted oxidation reactions: synthesis of solvatochromic 2,4,6-triarylpyrimidines. Tetrahedron Letters 50 (49) , pp. 6818-6822. 10.1016/j.tetlet.2009.09.116

Bagley, Mark Christopher, Davis, Terence, Dix, M. C., Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2008. Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 18 (13) , pp. 3745-3748. 10.1016/j.bmcl.2008.05.037

Torborg, C., Hughes, D. D., Buckle, R., Robinson, M. W. C., Bagley, Mark Christopher and Graham, A. E. 2008. Rapid ring-opening reactions of epoxides using microwave irradiation. Synthetic Communications 38 (2) , pp. 205-211. 10.1080/00397910701738982

John, Oliver R. S., Killeen, Niall M., Knowles, Deborah A., Yau, Sze Chak, Bagley, Mark Christopher and Tomkinson, Nicholas Charles Oliver 2007. Direct α-Oxytosylation of carbonyl compounds: One-pot synthesis of heterocycles. Organic Letters 9 (20) , pp. 4009-4012. 10.1021/ol701774y

Davis, Terence, Wyllie, Fiona Sandra, Rokicki, Michal J., Bagley, Mark C. and Kipling, David Glyn 2007. The Role of Cellular Senescence in Werner Syndrome: Toward Therapeutic Intervention in Human Premature Aging. Annals of the New York Academy of Sciences 1100 , pp. 455-469. 10.1196/annals.1395.051

Davis, Terence., Bagley, Mark Christopher, Dix, M. C., Murziani, Paola G. S., Rokicki, M. J., Widdowson, C. S., Zayed, J. M., Bachler, M. A. and Kipling, David Glyn 2007. Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38 alpha(MAPK) inhibitors in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 17 (24) , pp. 6832-6835. 10.1016/j.bmcl.2007.10.036

Merritt, E. A. and Bagley, Mark Christopher 2007. Holzapfel-Meyers-Nicolaou modification of the Hantzsch thiazole synthesis. Synthesis 22 , pp. 3535-3541. 10.1055/s-2007-990851

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Widdowson, Caroline S. and Kipling, David Glyn 2006. Microwave-assisted synthesis of N-pyrazole ureas and the p38 inhibitor BIRB 796 for study into accelerated cell ageing. Organic & biomolecular chemistry 4 (22) , pp. 4158-4164. 10.1039/b611493h

Bagley, Mark Christopher, Jenkins, Robert Leyshon, Lubinu, M. Caterina, Mason, Christopher and Wood, Robin 2005. A simple continuous flow microwave reactor. Journal of organic chemistry 70 (17) , pp. 7003-7006. 10.1021/jo0510235

Bagley, Mark Christopher, Chapaneri, Krishna, Dale, James W., Xiong, Xin and Bower, Justin 2005. One-Pot Multistep Bohlmann-Rahtz Heteroannulation Reactions: Synthesis of Dimethyl Sulfomycinamate. The Journal of Organic Chemistry 70 (4) , pp. 1389-1399. 10.1021/jo048106q

Bagley, Mark Christopher, Dale, James W., Ohnesorge, Maren, Xiong, Xin and Bower, Justin 2003. A Facile Solution Phase Combinatorial Synthesis of Tetrasubstituted Pyridines Using the Bohlmann-Rahtz Heteroannulation Reaction. Journal of Combinatorial Chemistry 5 (1) , pp. 41-44. 10.1021/cc020067d

This list was generated on Sun Dec 15 09:00:26 2019 GMT.