McNulty, Paul, Pilcher, Richard, Ramesh, Raviram, Necuiniate, Renata, Hughes, Alis, Farewell, Daniel ORCID: https://orcid.org/0000-0002-8871-1653, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412 and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2018. Reduced cancer incidence in Huntington's disease: analysis in the Registry study. Journal of Huntington's Disease 7 (3) , pp. 209-222. 10.3233/JHD-170263 |
Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X, Rushton, David J., Yarova, Polina, Schnell, Christian, Geater, Charlene, Hancock, Jane M., Wieland, Annalena, Hughes, Alis, Badder, Luned, Cope, Emma Louise, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Randall, Andrew, Brown, Jonathan T., Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X and Telezhkin, Vsevolod ORCID: https://orcid.org/0000-0002-5054-8774 2016. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology 594 (22) , pp. 6583-6594. 10.1113/JP270655 |
Bowles, Kathryn R., Brooks, Simon P., Hughes, Alis, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2016. Correction: Huntingtin Subcellular localisation is regulated by kinase signalling activity in the StHdhQ111 model of HD. PLoS ONE 11 (10) , e0165069. 10.1371/journal.pone.0165069 |
Townhill, Jenny, Hughes, Alis, Thomas, Benny, Busse, Monica ORCID: https://orcid.org/0000-0002-5331-5909, Price, Kathryn, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Hastings, Michael H. and Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 2016. Using Actiwatch to monitor circadian rhythm disturbance in Huntington' disease: A cautionary note. Journal of Neuroscience Methods 265 , pp. 13-18. 10.1016/j.jneumeth.2016.01.009 |
Telezhkin, Vsevolod, Schnell, Christian, Yarova, Polina L., Yung, Sun, Sanders, Philip, Cope, Emma, Hughes, Alis, Thompson, Belinda A, Geater, Charlene, Hancock, Jane M., Joy, Shona, Badder, Luned, Connor-Robson, Natalie ORCID: https://orcid.org/0000-0001-8350-6928, Comella, Andrea, Straccia, Marco, Bombau, Georgina, Brown, Jon T, Canals, Josep M., Randall, Andrew D., Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2016. Forced cell-cycle exit and modulation of GABAA, CREB and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology - Cell Physiology , ajpcell.00166.2015. 10.1152/ajpcell.00166.2015 |
Mort, Matthew Edwin, Carlisle, Francesca ORCID: https://orcid.org/0000-0002-9734-113X, Waite, Adrian, Elliston, Lyn, Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 and Hughes, Alis 2015. Huntingtin exists as multiple splice forms in human brain. Journal of Huntington's Disease 4 (2) , pp. 161-171. 10.3233/JHD-150151 |
Hughes, Alis, Mort, M., Carlisle, F. and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2014. B04 Alternative Splicing In Htt [Conference abstract]. Journal of Neurology, Neurosurgery & Psychiatry 85 (Suppl) , A10. 10.1136/jnnp-2014-309032.32 |
Hughes, Alis, Mort, Matthew Edwin, Elliston, Linda Anne, Thomas, Rhian M., Brooks, Simon Philip ORCID: https://orcid.org/0000-0001-9853-6177, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2014. Identification of novel alternative splicing events in the Huntingtin gene and assessment of the functional consequences using structural protein homology modelling. Journal of Molecular Biology 426 (7) , pp. 1428-1438. 10.1016/j.jmb.2013.12.028 |
Hughes, Alis and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2014. Pathogenic mechanisms in Huntington's disease. Bates, G., Tabrizi, S. and Jones, Lesley, eds. Huntington's Disease, 4th Edition, Oxford University Press, |
Grosset, Donald, Naveed, Malek, Aquino, Camila Catherine, Fox, Susan H., Williams, Susannah, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 and Hughes, Alis 2013. Journal Watch: Our panel of experts highlight the most important research articles across the spectrum of topics relevant to the field of neurodegenerative disease management. Neurodegenerative Disease Management 3 (4) , pp. 303-305. 10.2217/nmt.13.39 |
Hughes, Alis, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2012. E06 Family history curation in Huntington's disease: a survey of the data so far. Journal of Neurology, Neurosurgery & Psychiatry 83 (Suppl) , A21-A21. 10.1136/jnnp-2012-303524.65 |
Ho, A. K., Hocaoglu, M. B. and Hughes, Alis 2011. Impact of Huntington's across the entire disease spectrum: the phases and stages of disease from the patient perspective. Clinical Genetics 80 (3) , pp. 235-239. 10.1111/j.1399-0004.2011.01748.x |
Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 and Hughes, Alis 2011. Pathogenic mechanisms in Huntington's Disease. International Review of Neurobiology 98 , pp. 373-418. 10.1016/B978-0-12-381328-2.00015-8 |
Hughes, Alis and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2011. Huntingtin localisation studies - a technical review. Plos Currents 3 , RRN1211. 10.1371/currents.RRN1211 |
Hughes, Alis, Ersoy, N., Elliston, Linda Anne and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2010. Protein localisation studies: Where is Huntingtin hiding? [Meeting abstract]. Journal of Neurology, Neurosurgery and Psychiatry 81 (1) , A1. 10.1136/jnnp.2010.222570.3 |
Hughes, Alis, Price, Kathy, Mason, D, Evans, B, Pettit, R, Evans, W and Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 2010. F21 Is bone density altered in early stage huntington's disease patients? - a pilot study [Conference Abstract]. Journal of Neurology, Neurosurgery & Psychiatry 81 (Suppl) , A29-A29. 10.1136/jnnp.2010.222620.21 |
Creighton, S., Semaka, A., Hughes, Alis, Collins, J. A. and Hayden, M. R. 2009. The Huntington disease predictive testing experience in British Columbia, Canada [Conference Abstract]. Clinical Genetics 76 , p. 118. 10.1111/j.1399-0004.2009.01267.x |
Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Elford, Carole, Pexa, Annette, Francis, Karen, Hughes, Alis, Deussen, Andreas and Ham, Jack 2006. Human osteoblast precursors produce extracellular adenosine, which modulates their secretion of IL-6 and osteoprotegerin. Journal of Bone and Mineral Research 21 (2) , pp. 228-36. 10.1359/JBMR.051021 |
Hughes, Alis, Evans, B. A. J., Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753 and Mason, D. J. 2006. Do polyglutamine tracts in huntingtin influence glutamate signalling in bone? [Conference Abstract]. Calcified Tissue International 78 (S1) , S58-S58. |
Hughes, Alis, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Fricker-Gates, Rosemary and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612 2004. Endophilin A3 forms filamentous structures that colocalise with microtubules but not with actin filaments. Molecular Brain Research 128 (2) , pp. 182-192. 10.1016/j.molbrainres.2004.06.016 |