Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Synthesis and substrate-controlled reactions of 2,2′-unsaturated biquinazolinones

Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101, Nutz, Eva, Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897 and Coogan, Michael P. 2017. Synthesis and substrate-controlled reactions of 2,2′-unsaturated biquinazolinones. Tetrahedron 73 (1) , pp. 55-63. 10.1016/j.tet.2016.11.060

[thumbnail of Synthesis%20and%20Substrate-Controlled%20Reactions%20of%202,2_-Unsaturated%20Biquinazolinones.%20[1].pdf]
Preview
PDF - Accepted Post-Print Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (971kB) | Preview

Abstract

A series of BiQuinazolinones bearing either double or triple bonds in their lateral chains have been synthesized. These compounds were then subjected to substrate-controlled reactions such as Diels-Alder, epoxidation and Pauson-Khand reactions. The stereoselective outcome observed in these transformations is very promising for the future application of BiQuinazolinones as chiral auxiliaries.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Subjects: R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Uncontrolled Keywords: BiQuinazolinone; Atropisomers; Diastereoselectivity; Chiral induction
Publisher: Elsevier
ISSN: 0040-4020
Date of First Compliant Deposit: 23 January 2017
Date of Acceptance: 21 November 2016
Last Modified: 12 Nov 2023 09:25
URI: https://orca.cardiff.ac.uk/id/eprint/97657

Citation Data

Cited 1 time in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics