Slusarczyk, Magdalena ORCID: https://orcid.org/0000-0002-4707-7190, De Borggraeve, Wim M., Hoornaert, Georges, Deroose, Frederik and Linders, Joannes T. M. 2008. Synthesis and biological evaluation of methylene-bridged analogs of the potent cannabinoid receptor antagonist rimonabant. European Journal of Organic Chemistry 2008 (8) , pp. 1350-1357. 10.1002/ejoc.200700960 |
Official URL: http://dx.doi.org/10.1002/ejoc.200700960
Abstract
Methylene-bridged analogs of rimonabant were synthesized and evaluated for their activity on CB1 receptors. The pyrazine derivative showed some activity as a CB1 antagonist.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Pharmacy |
Subjects: | R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
Uncontrolled Keywords: | Heterocycles ; Cyclocondensation ; Diels–Alder reaction |
Publisher: | Wiley |
ISSN: | 1434-193X |
Last Modified: | 21 Oct 2022 09:33 |
URI: | https://orca.cardiff.ac.uk/id/eprint/36853 |
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