Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Role of the medial prefrontal cortex in acquired distinctiveness and equivalence of cues

Iordanova, Mihaela D., Killcross, Andrew Simon and Honey, Robert Colin ORCID: https://orcid.org/0000-0001-6870-1880 2007. Role of the medial prefrontal cortex in acquired distinctiveness and equivalence of cues. Behavioral Neuroscience 121 (6) , pp. 1431-1436. 10.1037/0735-7044.121.6.1431

Full text not available from this repository.

Abstract

In the present study, the authors examined the role of the medial prefrontal cortex in acquired equivalence and distinctiveness of cues. Rats were placed in 4 experimental contexts (A, B, C, and D) where they received presentations of 2 auditory stimuli (X and Y). In Contexts A and B, X was paired with food and Y was not, whereas in Contexts C and D, Y was paired with food and X was not. Rats that received sham lesions and those with lesions of the medial prefrontal cortex acquired this configural discrimination equally readily. Rats then received many pellets in A but not in C. After this training, sham-lesion rats exhibited more magazine activity in B than in D (an acquired distinctiveness/acquired equivalence effect), whereas those with medial prefrontal cortex lesions did not. These results indicate that the medial prefrontal cortex is involved in the process by which experience with stimuli influences the degree of generalization between them.

Item Type: Article
Status: Published
Schools: Psychology
Publisher: American Psychological Association
ISSN: 1939-0084
Last Modified: 20 Oct 2022 09:46
URI: https://orca.cardiff.ac.uk/id/eprint/33044

Citation Data

Cited 19 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item