Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Stereoselective ketone rearrangements with hypervalent iodine reagents

Malmedy, Florence and Wirth, Thomas 2016. Stereoselective ketone rearrangements with hypervalent iodine reagents. Chemistry - a European Journal 22 (45) 10.1002/chem.201603022

[img]
Preview
PDF - Accepted Post-Print Version
Download (857kB) | Preview

Abstract

The first stereoselective version of an iodine(III)-mediated rearrangement of arylketones in the presence of orthoesters is described. The reaction products, α-arylated esters, are very useful intermediates in the synthesis of bioactive compounds such as ibuprofen. With chiral lactic acid-based iodine(III) reagents product selectivities of up to 73 % ee have been achieved.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Publisher: WileyBlackwell
ISSN: 0947-6539
Date of First Compliant Deposit: 9 September 2016
Date of Acceptance: 26 July 2016
Last Modified: 12 Oct 2017 03:37
URI: http://orca-mwe.cf.ac.uk/id/eprint/94392

Citation Data

Cited 16 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics