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A pilot study on the stability of the human nasal cycle

Williams, Mark Robert 2016. A pilot study on the stability of the human nasal cycle. MPhil Thesis, Cardiff University.
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It is well recognised that nasal airflow (secondary to patency) is not constant and can be influenced factors such as exercise and disease. There are also periodic fluctuations, which occur termed the nasal cycle. The term “classical” nasal cycle has been applied to the periodic and reciprocal changes in nasal airflow and has been defined by Flanagan and Eccles numerically [1]. Nasal airflow data was collected using anterior rhinomanometry for 30 subjects over an eight hour period on two study days at an approximately 1 week interval. Subjects also used the Subjective Ordinal Scale to self assess prior to each set of nasal airflow measurements. All data was analysed using the r-value (correlation coefficient comparing left and right nasal airflow) and the Airflow Distribution Ratio, the Nasal Partitioning Ratio was also used for the comparison of objective and subjective data. The frequency of a “classical” nasal cycle within the subject group was comparable with that reported by Flanagan and Eccles at the first study day. The nasal cycle was demonstrated to be unstable for most subjects with only 37.5% of the subjects with a “classical” nasal cycle at study day 1 continuing in this group at study day 2. However a tendency towards reciprocity was demonstrated as overall r-values were seen to become more negative from study day 1 to study day 2 this was demonstrated by a correlation coefficient of -0.73 (p <0.001). The r-value was not found to be useful in conjunction with the Subjective Ordinal Scale as no correlation was found between subjective and objective values. A good correlation was found for the Airflow Distribution Ratio and the Nasal Partitioning Ratio (NPR) since the NPR can be used independently it may be useful as a tool in the subjective assessment of the nasal cycle.

Item Type: Thesis (MPhil)
Date Type: Publication
Status: Unpublished
Schools: Biosciences
Subjects: Q Science > QP Physiology
R Medicine > RF Otorhinolaryngology
Uncontrolled Keywords: Nasal Cycle; Rhinomanometry; Nasal Airflow; Reciprocal airflow patterns; Reciprocity; Central control; correlation coefficient; Airflow Distribution Ratio; Nasal Partitioning Ratio; Subjective assessment
Date of First Compliant Deposit: 28 September 2016
Last Modified: 10 Oct 2017 17:12

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