Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Matrix metalloproteinase 9 mRNA: An early prognostic marker for patients with acute stroke

Graham, Colin A., Chan, Rebecca W.Y., Chan, Dexter Y.S., Chan, Cangel P.Y., Wong, Lawrence K.S. and Rainer, Timothy 2011. Matrix metalloproteinase 9 mRNA: An early prognostic marker for patients with acute stroke. Clinical Biochemistry 45 (4-5) , pp. 352-355. 10.1016/j.clinbiochem.2011.12.006

Full text not available from this repository.

Abstract

To investigate matrix metalloproteinase 9 (MMP9) mRNA as a prognostic marker in stroke. Design and methods MMP9 mRNA concentrations in 126 stroke patients were analyzed using quantitative reverse transcription-polymerase chain reaction. Results The normalized MMP9 mRNA concentration was almost 3 times higher in non-survival patients compared to survival patients (P = 0.0002); and 1.9-fold higher in patients with post-stroke modified Rankin score (mRS) > 2 than patients with mRS ≤ 2 (P < 0.05). Conclusions MMP9 mRNA was a predictor of poor outcome and mortality in stroke.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Uncontrolled Keywords: Blood–brain barrier; Messenger RNA (mRNA); Matrix metalloproteinase 9 (MMP9); Prognostic; Stroke
Publisher: Elsevier
ISSN: 0009-9120
Date of Acceptance: 6 December 2011
Last Modified: 04 Jun 2017 09:17
URI: http://orca-mwe.cf.ac.uk/id/eprint/93028

Citation Data

Cited 22 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item