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Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility

Ho, Anthony M.-H., Dion, Peter W., Yeung, Janice H.H., Ng, Calvin S.H., Karmakar, Manoj K., Critchley, Lester A.H., Rainer, Timothy Hudson, Cheung, Chi Wai and Tay, Beng A. 2010. Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility. Resuscitation 81 (9) , pp. 1079-1081. 10.1016/j.resuscitation.2010.02.030

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Abstract

During trauma resuscitation involving massive transfusion, the best fresh-frozen plasma to packed red blood cells ratio is unknown. No randomised controlled trial (RCT) is available on this subject, although there are plenty of observational studies suggesting that the ratio should be about 1:1. This ratio also makes more physiological sense, and we suggest that in patients with massive and ongoing bleeding, it is a sensible strategy with which to start resuscitation.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Uncontrolled Keywords: Coagulopathy; Fresh-frozen plasma; Red blood cells; Transfusion; Trauma
Publisher: Elsevier
ISSN: 0300-9572
Date of Acceptance: 3 February 2010
Last Modified: 04 Jun 2017 09:15
URI: http://orca-mwe.cf.ac.uk/id/eprint/92713

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