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Validation of the APLS age-based vital signs reference ranges in a Chinese population

Chan, S.S.W., Cattermole, G.N., Leung, P.Y.M., Mak, P.S.K., Graham, C.A. and Rainer, Timothy Hudson 2011. Validation of the APLS age-based vital signs reference ranges in a Chinese population. Resuscitation 82 (7) , pp. 891-895. 10.1016/j.resuscitation.2011.02.039

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Reference ranges for vital signs may differ significantly among children of different ethnic origins. Aim (1) To validate the Advanced Paediatric Life Support (APLS) age-based vital signs reference ranges in Chinese children in Hong Kong. (2) To derive age-based centile curves for systolic blood pressure, heart rate and respiratory rate for Chinese children. (3) To summarize the reference ranges in a table format appropriate for applying APLS to ethnic Chinese patients. Method A cross-sectional study was performed on a population of healthy Chinese children recruited from 8 kindergartens and 6 primary schools in Hong Kong. Trained operators visit the sites to obtain measurements. Age-groups: small toddlers (12–23 months); pre-school (24–59 months); and school (60–143 months). Z-test was used to assess statistical significance for proportions of each parameter falling outside the APLS reference range. One-sample t-test was used for comparison with APLS means according to age-groups. LMS Chartmaker Pro v2.3 software was used to describe the data in centile curves. Results A total of 1353 patients (55.1% boys) were included. For heart rate, systolic blood pressure and respiratory rate respectively, 34.1%, 55.9% and 55.7% of corresponding measurements were outside the APLS age-based reference ranges. In the ‘pre-school’ and ‘school’ age-groups, the mean value for blood pressure is significantly higher, and the mean values for heart rate and respiratory rate significantly lower, in comparison to APLS mean values. Conclusion Independently derived vital signs reference ranges are more appropriate for use when applying APLS to Chinese patients in Hong Kong.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Uncontrolled Keywords: APLS; Vital signs; Reference standard; Ethnicity; Paediatrics; Resuscitation
Publisher: Elsevier
ISSN: 0300-9572
Date of Acceptance: 24 February 2011
Last Modified: 04 Jun 2017 09:15

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