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Early predictors of good health-related quality of life in patients with moderate and severe trauma: a 12-month prospective cohort study in Hong Kong [Abstract]

Graham, C. A., Rainer, Timothy, Yeung, J. H. and Poon, W. S. 2012. Early predictors of good health-related quality of life in patients with moderate and severe trauma: a 12-month prospective cohort study in Hong Kong [Abstract]. Annals of Emergency Medicine 60 (4) , S152. 10.1016/j.annemergmed.2012.06.463

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Abstract

Study Objective: There is very little published data on post-trauma health status, functional outcome and return to work in the developed world, including Hong Kong. The aim of this prospective multicentre, cohort study is to identify predictors of good health-related quality of life (HRQOL) 12 month post-injury in patients with moderate and major trauma in Hong Kong. Methods: Ethical approval was obtained to conduct a multi-centre prospective cohort study of trauma patients in Hong Kong. Four hundred trauma patients admitted to the Prince of Wales Hospital (PWH), Queen Elizabeth Hospital (QEH) and Tuen Mun Hospital (TMH) were recruited to follow-up for 12 months. Adult patients aged ≥18 years with moderate or major trauma (defined as an ISS >8) who were entered into the Hong Kong Trauma Registry were included. Health-related quality of life (HRQOL) was measured by SF36 at baseline, 1-month and 12-month post-injury. Good outcomes at 12-months were defined as the upper 25th centile of the PCS element of SF36. Results: During January 2010 - December 2011, In the 400 patients recruited to the study (mean age 53.3 years; range 18-106; 69.5% male), only 35.2% of patients' physical component summary (PCS) score were back to the HK norm at 12 months. In a univariate analysis, age <50 years (OR 2.4, P<0.05), no admission to ICU (OR 2.5, p<0.05), one month PCS (PCS Q3: OR 4.6, p<0.05; PCS Q4: OR 11.6, p<0.0001) and one month mental component summary (MCS Q4: OR 3.4, p<0.05) were significantly associated with 12 month better outcome of quality of life. However, after multivariate analysis only age <50 years (OR 3.3, p<0.001) and one month PCS (OR 9.7, p=0.001) persisted as significant predictors for the better outcome of quality of life at 12 month post injury. Conclusion: Moderate to severely injured patients have a 35% chance at one year of reaching the HK population norm. One year physical health status may be predicted by age and PCS at one month.

Item Type: Article
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Additional Information: ACEP Research Forum 2012
Publisher: Elsevier
ISSN: 0196-0644
Last Modified: 04 Jun 2017 09:15
URI: http://orca-mwe.cf.ac.uk/id/eprint/92660

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